David

White

All publications

Journal articles

• Griffiths AW, White S, Norman P, Coates E, Hartley H, Williams IA, Halliday V, Beever D, Hackney G, Stavroulakis T , HighCALS Study Group et al (2026) Development of a complex intervention to support high calorie diets for people with amyotrophic lateral sclerosis. Muscle and Nerve, 74(1), 149-158. View this article in WRRO
• Metwally M, McKendrick K, Ridsdale K, Pye C, Walters S, Amer S, Barr A, Chatters R, Cheong Y, Choudhary M , Connor M et al (2026) Removal of small fibroids and polyps in patients with infertility and recurrent miscarriage: The HELP Fertility? RCT.. Health Technol Assess, 1-35.
• Lumley E, O'Cathain A, Ridsdale K, Drabble S, White D, Pye C, Wright J, Drakeley A, Cheong Y, Mathur R , Barr A et al (2026) Views on outpatient paracentesis and GnRH antagonists for ovarian hyperstimulation syndrome: a qualitative study of patients and healthcare professionals.. Health Technol Assess, 1-14.
• Gould RL, Thompson BJ, Rawlinson CV, Bursnall M, Bradburn M, Keetharuth AD, Young T, Lawrence V, White DA, Howard RJ , Serfaty MA et al (2025) Acceptance and Commitment Therapy for people living with motor neuron disease: the COMMEND feasibility study and randomised controlled trial.. Health Technol Assess, 29(51), 1-28.
• Hullock K, O'Cathain A, Sampson F, Woodward J, Coates E, Stavroulakis T, White SM, White D, Norman P & McDermott C (2025) Optimising calorie intake for people with amyotrophic lateral sclerosis: a process evaluation of a complex behaviour change intervention. Health Expectations, 28(5). View this article in WRRO
• Peace A, White DA, Hackney G, Bradburn M, Norman P, White S, Al-Chalabi A, Baird W, Beever D, Cade J , Coates E et al (2025) Randomised controlled trial with parallel process evaluation and health economic analysis to evaluate a nutritional management intervention, OptiCALS, for patients with amyotrophic lateral sclerosis: study protocol. BMJ Open, 15(5). View this article in WRRO
• Burton C, Mooney C, Sutton L, White D, Dawson J, Fryer K, Greco M, Horspool M, Neilson A, Rowlands G , Sanders T et al (2025) Multiple symptoms study 3 – An extended-role general practitioner clinic for patients with persistent physical symptoms: a Randomised Controlled Trial. Health and Social Care Delivery Research, 1-24. View this article in WRRO
• Neilson AR, Mooney C, Sutton L, White D, Dawson J, Rowlands G, Thomas RE, Woodward J, Deary V & Burton C (2025) Cost-effectiveness of an extended-role general practitioner clinic for persistent physical symptoms: results from the Multiple Symptoms Study 3 pragmatic randomized controlled trial. Health and Social Care Delivery Research. View this article in WRRO
• Burton C, Mooney C, Sutton L, White D, Dawson J, Neilson AR, Rowlands G, Thomas S, Horspool M, Fryer K , Greco M et al (2025) Effectiveness of a symptom-clinic intervention delivered by general practitioners with an extended role for people with multiple and persistent physical symptoms in England: the Multiple Symptoms Study 3 pragmatic, multicentre, parallel-group, individually randomised controlled trial. Health and Social Care Delivery Research. View this article in WRRO
• Sanders T, Fryer K, Greco M, Mooney C, Deary V & Burton C (2025) Explanation for symptoms and biographical repair in a clinic for persistent physical symptoms. Health and Social Care Delivery Research. View this article in WRRO
• Fryer K, Sanders T, Greco M, Mooney C, Deary V & Burton C (2025) Recognition, explanation, action, learning: teaching and delivery of a consultation model for persistent physical symptoms. Health and Social Care Delivery Research. View this article in WRRO
• Rawlinson C, Gould RL, McDermott CJ, Thompson B, Weeks K, Gossage-Worrall R, Serfaty MA, Graham CD, McCracken L, White D , Howard RJ et al (2024) Experiences of acceptance and commitment therapy for people living with motor neuron disease (MND): a qualitative study from the perspective of people living with MND and therapists. The Cognitive Behaviour Therapist, 17. View this article in WRRO
• Neilson AR, Mooney C, Sutton L, White D, Dawson J, Rowlands G, Thomas RE, Woodward J, Deary V & Burton C (2024) Cost-effectiveness of an extended-role general practitioner clinic for persistent physical symptoms: results from the multiple symptoms study 3 pragmatic randomized controlled trial. Value in Health, 27(12), 1710-1721. View this article in WRRO
• Burton C, Mooney C, Sutton L, White D, Dawson J, Neilson AR, Rowlands G, Thomas S, Horspool M, Fryer K , Greco M et al (2024) Effectiveness of a symptom-clinic intervention delivered by general practitioners with an extended role for people with multiple and persistent physical symptoms in England: the Multiple Symptoms Study 3 pragmatic, multicentre, parallel-group, individually randomised controlled trial. The Lancet, 403(10444), 2619-2629. View this article in WRRO
• Gould RL, McDermott CJ, Thompson BJ, Rawlinson CV, Bursnall M, Bradburn M, Kumar P, Turton EJ, White DA, Serfaty MA , Graham CD et al (2024) Acceptance and Commitment Therapy plus usual care for improving quality of life in people with motor neuron disease (COMMEND): a multicentre, parallel, randomised controlled trial in the UK. The Lancet. View this article in WRRO
• Keetharuth AD, Gould R, McDermott C, Thompson B, Rawlinson C, Bradburn M, Bursnall M, Kumar P, Turton E, Tappenden P , White D et al (2024) Cost-effectiveness of acceptance and commitment therapy for people living with motor neuron disease, and their health-related quality of life. European Journal of Neurology, 31(8). View this article in WRRO
• White DA, Pye C, Ridsdale K, Dimairo M, Mooney C, Wright J, Young TA, Cheong YC, Drakeley A, Mathur R , O'Cathain A et al (2024) Outpatient paracentesis for the management of ovarian hyperstimulation syndrome: study protocol for the STOP-OHSS randomised controlled trial. BMJ Open, 14. View this article in WRRO
• Lombardo FL, Spila Alegiani S, Mayer F, Cipriani M, Lo Giudice M, Ludolph AC, McDermott CJ, Corcia P, Van Damme P, Van den Berg LH , Hardiman O et al (2023) A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial. Trials, 24(1). View this article in WRRO
• White D, Sutton L, Mooney C, Dawson J & Burton C (2023) SWAT 137: A 2x2 randomised factorial SWAT of the use of a pen and brief information leaflet to improve recruitment in a randomised controlled trial of a community-based clinic for patients with persistent physical symptoms [version 1; peer review: awaiting peer review]. F1000Research, 12. View this article in WRRO
• Gould RL, Rawlinson C, Thompson B, Weeks K, Gossage-Worrall R, Cantrill H, Serfaty MA, Graham CD, McCracken LM, White D , Howard RJ et al (2023) Acceptance and commitment therapy for people living with motor neuron disease: an uncontrolled feasibility study. Pilot and Feasibility Studies, 9. View this article in WRRO
• Tesfaye S, Sloan G, White D, Bradburn M, Bouhassira D & Selvarajah D (2023) Who really benefits from drug combinations and long titrations for pain? – Authors' reply. The Lancet, 401(10372), 192-193. View this article in WRRO
• Coates E, Zarotti N, Williams I, White S, Halliday V, Beever D, Hackney G, Stavroulakis T, White D, Norman P & McDermott C (2023) Patient, carer and healthcare professional perspectives on increasing calorie intake in Amyotrophic Lateral Sclerosis. Chronic Illness, 19(2), 368-382. View this article in WRRO
• Mooney C, White D, Dawson J, Deary V, Fryer K, Greco M, Horspool M, Neilson AR, Rowlands G, Sanders T , Thomas RE et al (2022) Study protocol for the Multiple Symptoms Study 3: a pragmatic, randomised controlled trial of a clinic for patients with persistent (medically unexplained) physical symptoms. BMJ Open, 12(11). View this article in WRRO
• Gould RL, Thompson BJ, Rawlinson C, Kumar P, White D, Serfaty MA, Graham CD, McCracken LM, Bursnall M, Bradburn M , Young T et al (2022) A randomised controlled trial of acceptance and commitment therapy plus usual care compared to usual care alone for improving psychological health in people with motor neuron disease (COMMEND): study protocol. BMC Neurology, 22(1).
• Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Young T, Rajbhandari S, Sharma S, Rayman G, Gouni R , Alam U et al (2022) Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT. Health Technology Assessment, 26(39).
• Albanese A, Ludolph AC, McDermott CJ, Corcia P, Van Damme P, Van den Berg LH, Hardiman O, Rinaldi G, Vanacore N & Dickie B (2022) Tauroursodeoxycholic acid in patients with amyotrophic lateral sclerosis: the TUDCA-ALS trial protocol. Frontiers in Neurology, 13. View this article in WRRO
• Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Julious S, Rajbhandari S, Sharma S, Rayman G, Gouni R , Alam U et al (2022) Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial. The Lancet, 400(10353), 680-690.
• Metwally M, Chatters R, Pye C, Dimairo M, White D, Walters S, Cohen J, Young T, Cheong Y, Laird S , Mohiyiddeen L et al (2022) Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation : RCT and systematic review. Health Technology Assessment, 26(10), 1-211. View this article in WRRO
• Metwally M, Chatters R, White D, Hall J & Walters S (2022) Endometrial scratch in women undergoing first-time IVF treatment : a systematic review and meta-analysis of randomized controlled trials. Reproductive BioMedicine Online, 44(4), 617-629. View this article in WRRO
• Chatters R, White D, Pye C, Petrovic A, Sizer A, Kumar P & Metwally M (2021) Experiences of trial participants and site staff of participating in and running a large randomised trial within fertility (the endometrial scratch trial): a qualitative interview study. BMJ Open, 11(9). View this article in WRRO
• Metwally M, Chatters R, Dimairo M, Walters S, Pye C, White D, Bhide P, Chater T, Cheong Y, Child T , Choudhary M et al (2021) A randomised controlled trial to assess the clinical effectiveness and safety of the endometrial scratch procedure prior to first-time IVF, with or without ICSI. Human Reproduction, 36(7), 1841-1853. View this article in WRRO
• White S, Zarotti N, Beever D, Bradburn M, Norman P, Coates E, Stavroulakis T, White D, McGeachan A, Williams I , Hackney G et al (2021) The nutritional management of people living with Amyotrophic Lateral Sclerosis (ALS): A national survey of dietitians. Journal of Human Nutrition and Dietetics, 34(6), 1064-1071. View this article in WRRO
• Bradburn MJ, Lee EC, White DA, Hind D, Waugh NR, Cooke DD, Hopkins D, Mansell P & Heller SR (2020) Treatment effects may remain the same even when trial participants differed from the target population. Journal of Clinical Epidemiology, 124, 126-138. View this article in WRRO
• Essat M, Archer R, Williams I, Zarotti N, Coates E, Clowes M, Beever D, Hackney G, White S, Stavroulakis T , White D et al (2020) Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system : a systematic review. Clinical Nutrition, 39(8), 2547-2556. View this article in WRRO
• Biggs K, Hind D, Gossage-Worrall R, Sprange K, White D, Wright J, Chatters R, Berry K, Papaioannou D, Bradburn M , Walters SJ et al (2020) Challenges in the design, planning and implementation of trials evaluating group interventions. Trials, 21. View this article in WRRO
• Zarotti N, Coates E, McGeachan A, Williams I, Beever D, Hackney G, Norman P, Stavroulakis T, White D, White S , Halliday V et al (2019) Health care professionals’ views on psychological factors affecting nutritional behaviour in people with motor neuron disease : a thematic analysis. British Journal of Health Psychology, 24(4), 953-969. View this article in WRRO
• Weeks K, Gould R, McDermott C, Lynch J, Goldstein L, Graham C, McCracken L, Serfaty M, Howard R, Al-Chalabi A , White D et al (2019) Needs and preferences for psychological interventions of people with motor neuron disease. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 20(7-8), 521-531. View this article in WRRO
• Selvarajah D, Petrie J, White D, Julious S, Bortolami O, Cooper C, Bradburn M, Loban A, Bowler H, Swaby L , Sutherland K et al (2018) Multicentre, double-blind, crossover trial to identify the Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM): study protocol for a randomised controlled trial. Trials, 19. View this article in WRRO
• Pollard DJ, Brennan A, Dixon S, Waugh N, Elliott J, Heller S, Lee E, Campbell M, Basarir H & White D (2018) The cost-effectiveness of insulin pumps compared to multiple daily injections, both provided with structured education, for adults with type 1 diabetes: a health economic analysis of the relative effectiveness of pumps over structured education (REPOSE) randomised controlled trial. BMJ Open, 8. View this article in WRRO
• Heller S, White D, Lee E, Lawton J, Pollard D, Waugh N, Amiel S, Barnard K, Beckwith A, Brennan A , Campbell M et al (2017) A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial.. Health Technology Assessment, 21(20), 1-278. View this article in WRRO
• Heller S, Amiel S, Campbell M, Choudhary P, Cooper C, Dimairo M, Elliott J, Hammond P, Lee E, Lindsay R , Waugh N et al (2017) Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE). BMJ, 356. View this article in WRRO
• Gilbody S, Brabyn S, Lovell K, Kessler D, Devlin T, Smith L, Araya R, Barkham M, Bower P, Cooper S , Knowles S et al (2017) Telephone-supported computerised cognitive-behavioural therapy: REEACT-2 large-scale pragmatic randomised controlled trial.. The British Journal of Psychiatry.
• Lawton J, White D, Rankin D, Elliott J, Taylor C, Cooper C, Heller S & Hallowell N (2017) Staff experiences of closing out a clinical trial involving withdrawal of treatment: qualitative study. Trials, 18. View this article in WRRO
• Brabyn S, Araya R, Barkham M, Bower P, Cooper C, Duarte A, Kessler D, Knowles S, Lovell K, Littlewood E , Mattock R et al (2016) The second Randomised Evaluation of the Effectiveness, cost-effectiveness and Acceptability of Computerised Therapy (REEACT-2) trial: does the provision of telephone support enhance the effectiveness of computer-delivered cognitive behaviour therapy? A randomised controlled trial.. Health Technology Assessment, 20(89), 1-64.
• Lawton J, Kirkham J, Rankin D, White DA, Elliott J, Jaap A, Smithson WH, Heller S, Gianfrancesco C, Gordon V , Greaves L et al (2016) Who gains clinical benefit from using insulin pump therapy? A qualitative study of the perceptions and views of health professionals involved in the Relative Effectiveness of Pumps over MDI and Structured Education (REPOSE) trial. Diabetic Medicine, 33(2), 243-251.
• Littlewood E, Duarte A, Hewitt C, Knowles S, Palmer S, Walker S, Andersen P, Araya R, Barkham M, Bower P , Brabyn S et al (2015) A randomised controlled trial of computerised cognitive behaviour therapy for the treatment of depression in primary care: the Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy (REEACT) trial. HEALTH TECHNOLOGY ASSESSMENT, 19(101), 1-+. View this article in WRRO
• White D & Hind D (2015) Projection of participant recruitment to primary care research: a qualitative study.. Trials, 16. View this article in WRRO
• Lawton J, Kirkham J, White D, Rankin D, Cooper C & Heller S (2015) Uncovering the emotional aspects of working on a clinical trial: a qualitative study of the experiences and views of staff involved in a type 1 diabetes trial. Trials, 16. View this article in WRRO
• Gilbody S, Littlewood E, Hewitt C, Brierley G, Tharmanathan P, Araya R, Barkham M, Bower P, Cooper C, Gask L , Kessler D et al (2015) Computerised cognitive behaviour therapy (cCBT) as treatment for depression in primary care (REEACT trial): large scale pragmatic randomised controlled trial.. BMJ, 351. View this article in WRRO
• Lawto J, Kirkham J, Rankin D, Barnard K, Cooper CL, Taylor C, Heller S, Elliott J & the REPOSE Group (2014) Perceptions and experiences of using automated bolus advisors amongst people with type 1 diabetes: A longitudinal qualitative investigation. Diabetes Research and Clinical Practice, 106(3), 443-450. View this article in WRRO
• White D, Waugh N, Elliott J, Lawton J, Barnard K, Campbell MJ, Dixon S, Heller S & REPOSE group (2014) The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled trial. BMJ OPEN, 4(9). View this article in WRRO
• Sotir F, White D, Wheeler G, Rodd H & Marshman Z () Protocol for a feasibility study of a self-help resource based on the principles of cognitive behavioural therapy to reduce needle fear in young people aged 11- to 16 years. Pilot and Feasibility Studies.
• Metwally M, Ridsdale K, Pye C, Dimairo M, Barr A, Cheong Y, Desoysa L, Drabble S, Drakeley A, Evbuomwan I , Flight L et al () Outpatient paracentesis for Ovarian Hyperstimulation Syndrome: STOP-OHSS feasibility study and RCT Synopsis. Health Technology Assessment, 1-34.
• Gould RL, Callaghan T, White D, Wetherell JL, Bursnall M, Bradburn M, Wailoo A, Serfaty MA, Graham CD, Howard RJ , Wilkinson P et al () A randomised controlled trial of Acceptance and Commitment Therapy plus usual care in comparison to usual care alone for reducing anxiety in older people with treatment-resistant generalised anxiety disorder (CONTACT-GAD): trial protocol. BMC Geriatrics.

Conference proceedings

• White S, Zarotti N, Beever D, Bradburn M, Norman P, Coates E, Stavroulakis T, White D, McGeachan A, Williams IA , Hackney G et al (2022) The nutritional management of people living with Amyotrophic Lateral Sclerosis (ALS): a cross-sectional survey of UK dietitians’. Clinical Nutrition ESPEN, Vol. 48 (pp 510-510). Brighton, UK, 30 November 2021 - 30 November 2021. View this article in WRRO
• White S, Baird O, Beever D, Brading L, Coates E, Hackney G, Hartley H, Quinn A, Stavroulakis T, White D , Norman P et al (2021) CMS-55 Development of the OptiCALS nutritional support intervention for people with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Vol. 22(sup2) (pp 232-233). Virtual conference, 7 December 2021 - 7 December 2021. View this article in WRRO
• Metwally M, Chatters R, Pye C, Dimairo M, White D, Walters S, Cohen J, Chater T, Pemberton K, Young T , Lomas R et al (2020) O-309 Endometrial scratching in women undergoing their first In Vitro Fertilisation (IVF) cycle: results from the UK Multicentre Endometrial Scratch Randomised Controlled Trial. Human Reproduction, Vol. 35(Supplement 1) (pp 140-141). Virtual, 5 July 2020 - 5 July 2020. View this article in WRRO
• Bradburn M, Lee E, White D, Hind D & Heller S (2019) Do RCTs reflect patient populations and does it matter? Considerations and a case study. Trials, Vol. 20(Supplement 1) (pp 124-124). Brighton, UK, 6 October 2019 - 6 October 2019. View this article in WRRO
• Rex SS, White D, Chatters R & Bradburn M (2019) Factors that affect attrition in RCTs for the treatment of depression. Trials, Vol. 20(Suppl 1) (pp 53-54). Brighton, UK, 6 October 2019 - 6 October 2019. View this article in WRRO
• White D, Lawton J, Rankin D, Elliott J, Taylor C, Cooper C, Heller S & Hallowell N (2017) Staff experiences of closing out a clinical trial involving withdrawal of treatment : qualitative study. Trials, Vol. 18(Suppl 1) (pp 91-91). Liverpool, UK, 7 May 2017 - 7 May 2017. View this article in WRRO
• White D, Lawton J, Rankin D, Elliott J, Taylor C, Cooper C, Heller S & Hallowell N (2017) Staff experiences of closing out a clinical trial involving withdrawal of treatment: qualitative study. TRIALS, Vol. 18
• White D & Hind D (2015) Projection of participant recruitment to primary care research. Trials, Vol. 16(S2)

Posters

• Biggs K, Hind D, Gossage-Worrall R, Sprange K, White D, Wright J, Chatters R, Berry K, Papaioannou D, Bradburn M , Walters SJ et al (2019) Challenges in the design, planning and implementation of trials evaluating group interventions. 5th International Clinical Trials Methodology Conference (ICTMC 2019). View this article in WRRO

Datasets

• White D, Sutton L, Mooney C, Dawson J & Burton C MSS3 SWAT data.
• White D, Sutton L, Mooney C, Dawson J & Burton C MSS3 aggregate SWAT data.

Preprints

• Williams IA, Essat M, Beever D, Clowes M, Coates E, Halliday V, White S, White D, Stavroulakis T, Zarotti N , Norman P et al (2026) Factors associated with oral nutritional behaviours in Neurodegenerative Disorders of the motor system: A systematic review, Center for Open Science.
• Metwally M, Ridsdale K, Dimairo M, Pye C, Cheong Y, Desoysa L, Drakely A, Evbuomwan I, Hughes J, Loban A , Mathur R et al (2025) Ovarian Hyperstimulation Syndrome: The STOP-OHSS RCT of outpatient paracentesis and survey on preventive practices, Cold Spring Harbor Laboratory.