Research Impact Our reputation for excellence attracts some of the best minds in the world who conduct research that has a real impact. You are here Home School of Medicine and Population Health Research Research Impact The Goldilocks Collar A special collar developed by University scientists has been giving the independence back to motor neurone disease patients all over the world. Our patient-centred approach to transforming lives Dead cells disrupt how immune cells respond to wounds and patrol for infection Our research paves the way for new therapies to manipulate how white blood cells get to and are kept at sites of injuries during healing The study Inhibitor of oxidative DNA repair presents with a new concept for treatment of inflammation A first-in-class OGG1 inhibitor found to decrease lung inflammation in mice and could hold the key to treating lung disorders The discovery Aspirin and omega-3 reduce pre-cancerous bowel polyps Clinical trial found that both aspirin and omega-3 reduced the number of bowel polyps in patients one year on from a screening colonoscopy The trial Promising drug for Parkinson’s disease: Study supports fast track to clinical trials A drug which has already been in use for decades to treat liver disease could be an effective treatment to slow down progression of Parkinson’s disease, scientists from the University of Sheffield have discovered. Learn more Build-up of DNA damage in nerve cells can lead to dementia High levels of DNA damage in nerve cells can lead to dementia, researchers from the University of Sheffield have found. Learn more A new gold standard treatment for the emergency correction of warfarin-induced coagulopathy As a result of research undertaken by the University of Sheffield between 1995-2002, a new gold standard treatment for major bleeding when using warfarin has been established. Learn more Example of a healthy mouth Interleukin-1 gene biomarkers revolutionise personalised dental healthcare in the USA Leading research carried out at the University of Sheffield on how the cytokine, interleukin-1 works in the body was used to justify the introduction of genetic testing by insurance companies for dental healthcare in the USA. Learn more Commercial impact of a Sheffield Spin-out: Asterion Ltd Many drugs require frequent injections, making them inconvenient, unattractive to patients and increasing the risk of infection. Learn more New drug for heart attack victims This case study describes how the trial and introduction of a new clinical treatment for heart attack patients improves their prognosis. Learn more Predicting Preterm Birth—Success with translational research funding applications Read more Diurnal: Developing Circadian Hormone Therapy to Improve Health Read more Investigating a potential treatment for IBS Read more Reducing fracture risk in osteoporosis with Zoledronic Acid Read more Improving health using circadian hormone therapy Read more FRAX® – a tool to assess fracture risk in osteoporosis. Read more It’s in your blood: Links found between blood type and risk of cognitive decline Read more Motor neurone disease: New technologies boost quality of life Read more