Professor Steven A Julious

All publications

Books

• Julious S, Say-Beng T & Machin D (2010) An Introduction to Statistics in Early Phase Trials. Wiley-Blackwell.
• Julious SA (2009) Samples Sizes for Clinical Trials. Chapman & Hall/CRC.
• Julious SA () Sample Sizes for Clinical Trials. Chapman and Hall/CRC.

Journal articles

• Zhang Q, Dimairo M, Julious SA, Lewis J & Yu Z (2024) Reporting and communication of sample size calculations in adaptive clinical trials: a review of trial protocols and grant applications. BMC Medical Research Methodology, 24(1). View this article in WRRO
• Chatters R, Hawksworth O, Julious S & Cook A (2024) The development of a set of key points to aid clinicians and researchers in designing and conducting n-of-1 trials. Trials, 25(1). View this article in WRRO
• Totton N, Waddingham E, Owen R, Julious S, Hughes D & Cook J (2024) A proposal for using benefit-risk methods to improve the prominence of adverse event results when reporting trials. Trials, 25(1), 409.
• Salsbury JA, Oakley JE, Julious SA & Hampson LV (2024) Assurance methods for designing a clinical trial with a delayed treatment effect. Statistics in Medicine. View this article in WRRO
• Totton N, Lin J, Julious S, Chowdhury M & Brand A (2023) A review of sample sizes for UK pilot and feasibility studies on the ISRCTN registry from 2013 to 2020. Pilot and Feasibility Studies, 9(1), 188.
• Alyami RA, Simpson R, Oliver P & Julious SA (2023) Evaluation of the impact of letters to GP practices to promote asthma prescription uptake in school-age children during summer (TRAINS study): a pragmatic cluster-randomised controlled trial. The Lancet, 402, S22-S22.
• Bageta ML, Balboa PL, Glover R, Cooper C, Papaioannou DE, Julious S, Dimairo M, Biggs K, Petrof G & Martinez AE (2023) O08 Mesenchymal stromal cells infusions in children with recessive dystrophic epidermolysis bullosa (MissionEB): a randomized controlled trial. British Journal of Dermatology, 189(3), e42-e43.
• Junqueira DR, Zorzela L, Golder S, Loke Y, Gagnier JJ, Julious SA, Li T, Mayo-Wilson E, Pham B, Phillips R , Santaguida P et al (2023) CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomized trials. Journal of Clinical Epidemiology.
• Edwards JM, Walters SJ & Julious SA (2023) A retrospective analysis of conditional power assumptions in clinical trials with continuous or binary endpoints. Trials, 24.
• Iflaifel M, Sprange K, Bell J, Cook A, Gamble C, Julious SA, Juszczak E, Linsell L, Montgomery A & Partlett C (2023) Developing guidance for a risk-proportionate approach to blinding statisticians within clinical trials: a mixed methods study. Trials, 24.
• Khoo SH, FitzGerald R, Saunders G, Middleton C, Ahmad S, Edwards CJ, Hadjiyiannakis D, Walker L, Lyon R, Shaw V , Mozgunov P et al (2022) Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2 trial. The Lancet Infectious Diseases.
• Alyami RA, Simpson R, Oliver P & Julious SA (2022) TRial to Assess Implementation of New research in a primary care Setting (TRAINS): study protocol for a pragmatic cluster randomised controlled trial of an educational intervention to promote asthma prescription uptake in general practitioner practices. Trials, 23.
• Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Julious S, Rajbhandari S, Sharma S, Rayman G, Gouni R , Alam U et al (2022) Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial. The Lancet, 400(10353), 680-690.
• Duro EM, Julious SA & Ren S (2022) An investigation of the constancy of effect in Cochrane systematic reviews in context with the assumptions for noninferiority trials. BMC Medical Research Methodology, 22(1).
• Iflaifel M, Partlett C, Bell J, Cook A, Gamble C, Julious S, Juszczak E, Linsell L, Montgomery A & Sprange K (2022) Blinding of study statisticians in clinical trials : a qualitative study in UK clinical trials units. Trials, 23(1).
• Flight L & Julious SA (2022) Practical guide to sample size calculations: Installation of the app SampSize.. Pharm Stat.
• Flight L, Julious S, Brennan A & Todd S (2021) Expected value of sample information to guide the design of group sequential clinical trials. Medical Decision Making. View this article in WRRO
• Rothwell JC, Julious SA & Cooper CL (2021) Adjusting for bias in the mean for primary and secondary outcomes when trials are in sequence. Pharmaceutical Statistics.
• Lewis J & Julious SA (2021) Sample sizes for cluster-randomised trials with continuous outcomes: Accounting for uncertainty in a single intra-cluster correlation estimate. Statistical Methods in Medical Research, 30(11), 2459-2470. View this article in WRRO
• Stanley B, Davis A, Jones R, Julious S, Ryan D, Jackson D, Halpin D, Pinnock H, Quint J, Khunti K , Heaney L et al (2021) Characteristics of patients in platform C19, a COVID-19 research database combining primary care electronic health record and patient reported information. PLoS ONE, 16(10). View this article in WRRO
• Jones R, Davis A, Stanley B, Julious S, Ryan D, Jackson DJ, Halpin DMG, Hickman K, Pinnock H, Quint JK , Khunti K et al (2021) Risk predictors and symptom features of long COVID within a broad primary care patient population including both tested and untested patients. Pragmatic and Observational Research, 12, 93-104. View this article in WRRO
• Totton N, Julious S, Hughes D, Cook J, Biggs K, Coates L, Cook A, Hewitt C & Day S (2021) Utilising benefit-risk assessments within clinical trials—a protocol for the BRAINS project. Trials, 22. View this article in WRRO
• Edwards JM, Walters SJ, Kunz C & Julious SA (2020) A systematic review of the “promising zone” design. Trials, 21. View this article in WRRO
• Latimer NR, Bhadhuri A, Alshreef AO, Palmer R, Cross E, Dimairo M, Julious S, Cooper C, Enderby P, Brady MC , Bowen A et al (2020) Self-managed, computerised word finding therapy as an add-on to usual care for chronic aphasia post-stroke : an economic evaluation. Clinical Rehabilitation. View this article in WRRO
• Dimairo M, Pallmann P, Wason J, Todd S, Jaki T, Julious SA, Mander AP, Weir CJ, Koenig F, Walton MK , Nicholl JP et al (2020) The adaptive designs CONSORT extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. Trials, 21(1). View this article in WRRO
• Dimairo M, Pallmann P, Wason J, Todd S, Jaki T, Julious SA, Mander AP, Weir CJ, Koenig F, Walton MK , Nicholl JP et al (2020) The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. BMJ, 369. View this article in WRRO
• Palmer R, Dimairo M, Latimer N, Cross E, Brady M, Enderby P, Bowen A, Julious S, Harrison M, Alshreef A , Bradley E et al (2020) Computerised speech and language therapy or attention control added to usual care for people with long-term post-stroke aphasia : the Big CACTUS three-arm RCT. Health Technology Assessment, 24(19), 1-176. View this article in WRRO
• Flight L, Julious S, Brennan A, Todd S & Hind D (2020) How can health economics be used in the design and analysis of adaptive clinical trials? A qualitative analysis. Trials, 21(1). View this article in WRRO
• Herbert E, Julious SA & Goodacre S (2019) Progression criteria in trials with an internal pilot : an audit of publicly funded randomised controlled trials. Trials, 20(1). View this article in WRRO
• Sones W, Julious SA, Rothwell JC, Ramsay CR, Hampson LV, Emsley R, Walters SJ, Hewitt C, Bland M, Fergusson DA , Berlin JA et al (2019) Correction to: Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial – the development of the DELTA2 guidance. Trials, 20(1).
• Cook JA, Julious SA, Sones W, Hampson LV, Hewitt C, Berlin JA, Ashby D, Emsley R, Fergusson DA, Walters SJ , Wilson ECF et al (2019) Practical help for specifying the target difference in sample size calculations for RCTs : the DELTA2 five-stage study, including a workshop. Health Technology Assessment, 23(60), 1-88. View this article in WRRO
• Palmer R, Dimairo M, Cooper C, Enderby P, Brady M, Bowen A, Latimer N, Julious S, Cross E, Alshreef A , Harrison M et al (2019) Self-managed, computerised speech and language therapy for patients with chronic aphasia post-stroke compared with usual care or attention control (Big CACTUS) : a multicentre, single-blinded, randomised controlled trial. The Lancet Neurology, 18(9), 821-833. View this article in WRRO
• Flight L, Arshad F, Barnsley R, Patel K, Julious S, Brennan A & Todd S (2019) A Review of Clinical Trials with an Adaptive Design and Health Economic Analysis. Value in Health. View this article in WRRO
• Dimairo M, Coates E, Pallmann P, Todd S, Julious SA, Jaki T, Wason J, Mander AP, Weir CJ, Koenig F , Walton MK et al (2018) Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design. BMC Medicine, 16. View this article in WRRO
• Julious SA (2018) Calculation of confidence intervals for a finite population size.. Pharmaceutical Statistics. View this article in WRRO
• Cook JA, Julious SA, Sones W, Hampson LV, Hewitt C, Berlin JA, Ashby D, Emsley R, Fergusson DA, Walters SJ , Wilson ECF et al (2018) DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial. BMJ (Online), 363. View this article in WRRO
• Cook JA, Julious SA, Sones W, Hampson LV, Hewitt C, Berlin JA, Ashby D, Emsley R, Fergusson DA, Walters SJ , Wilson ECF et al (2018) DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial. Trials, 19. View this article in WRRO
• Selvarajah D, Petrie J, White D, Julious S, Bortolami O, Cooper C, Bradburn M, Loban A, Bowler H, Swaby L , Sutherland K et al (2018) Multicentre, double-blind, crossover trial to identify the Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM): study protocol for a randomised controlled trial. Trials, 19(1), 578-578. View this article in WRRO
• Sones W, Julious SA, Rothwell JC, Ramsay CR, Hampson LV, Emsley R, Walters SJ, Hewitt C, Bland M, Fergusson DA , Berlin JA et al (2018) Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA2 guidance.. Trials, 19(542). View this article in WRRO
• Rothwell JC, Julious SA & Cooper CL (2018) A study of target effect sizes in randomised controlled trials published in the Health Technology Assessment journal.. Trials, 19. View this article in WRRO
• Buelo A, McLean S, Julious S, Flores-Kim J, Bush A, Henderson J, Paton JY, Sheikh A, Shields M & Pinnock H (2018) At-risk children with asthma (ARC): A systematic review. Thorax, 73(9), 813-824. View this article in WRRO
• Julious SA, Horspool MJ, Davis S, Franklin M, Smithson WH, Norman P, Simpson RM, Elphick H, Bortolami O & Cooper C (2018) Open-label, cluster randomised controlled trial and economic evaluation of a brief letter from a GP on unscheduled medical contacts associated with the start of the school year: The PLEASANT trial. BMJ Open, 8(4). View this article in WRRO
• Cooper CL, Whitehead A, Pottrill E, Julious SA & Walters SJ (2018) Are pilot trials useful for predicting randomisation and attrition rates in definitive studies: A review of publicly funded trials. Clinical Trials, 15(2), 189-196. View this article in WRRO
• Liu F, Walters SJ & Julious SA (2017) Design considerations and analysis planning of a phase 2a proof of concept study in rheumatoid arthritis in the presence of possible non-monotonicity. BMC Medical Research Methodology, 17(1). View this article in WRRO
• Cook JA, Julious SA, Sones W, Rothwell JC, Ramsay CR, Hampson LV, Emsley R, Walters SJ, Hewitt C, Bland M , Fergusson DA et al (2017) Choosing the target difference ('effect size') for a randomised controlled trial - DELTA² guidance protocol. Trials, 18. View this article in WRRO
• Franklin M, Davis S, Horspool M, Kua WS & Julious S (2017) Economic Evaluations Alongside Efficient Study Designs Using Large Observational Datasets: the PLEASANT Trial Case Study. PharmacoEconomics, 35(5), 561-573. View this article in WRRO
• Tagiyeva N, McLean S, Sheikh A, Julious S, Thomas M, Paton J, Pinnock H & Members of the ARC group (2017) Protocol for a systematic review to identify and weight the indicators of risk of asthma exacerbations in children aged 5-12 years.. NPJ Prim Care Respir Med, 27, 16088-16088. View this article in WRRO
• Posadzki P, Mastellos N, Ryan R, Gunn LH, Felix LM, Pappas Y, Gagnon MP, Julious SA, Xiang L, Oldenburg B & Car J (2016) Automated telephone communication systems for preventive healthcare and management of long-term conditions. Cochrane Database of Systematic Reviews, 2016(12). View this article in WRRO
• Flight L & Julious SA (2016) Corrections: The disagreeable behaviour of the kappa statistic. Pharmaceutical Statistics. View this article in WRRO
• Julious SA, Horspool MJ, Davis S, Bradburn M, Norman P, Shephard N, Cooper CL, Smithson WH, Boote J, Elphick H , Loban A et al (2016) PLEASANT: Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term - a cluster randomised controlled trial and economic evaluation.. Health Technology Assessment, 20(93), 1-154. View this article in WRRO
• Araujo A, Julious S & Senn S (2016) Understanding Variation in Sets of N-of-1 Trials. PLOS ONE, 11(12). View this article in WRRO
• McCleary N, Andrews A, Morrow S, Wiener-Ogilvie S, Fletcher M, Steed L, Taylor SJC, Pinnock H, team OBOTI, Sheikh A , McKinstry B et al (2016) Educating professionals to support self-management in people with asthma or diabetes: protocol for a systematic review and scoping exercise. BMJ Open, 6(10), e011937-e011937. View this article in WRRO
• Flight L, Julious SA & Goodacre S (2016) Can emergency medicine research benefit from adaptive design clinical trials?. Emergency Medicine Journal, 34, 243-248. View this article in WRRO
• Whitehead AL, Julious SA, Cooper CL & Campbell MJ (2016) Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable. Statistical Methods in Medical Research, 25(3), 1057-1073. View this article in WRRO
• Julious SA (2016) Pilot Studies in clinical research. Statistical Methods in Medical Research, 25(3), 995-996. View this article in WRRO
• Hatfield I, Allison A, Flight L, Julious SA & Dimairo M (2016) Adaptive designs undertaken in clinical research: a review of registered clinical trials. Trials, 17(1). View this article in WRRO
• Boote J, Julious S, Horspool M, Elphick H, Smithson WH & Norman P (2016) PPI in the PLEASANT trial: involving children with asthma and their parents in designing an intervention for a randomised controlled trial based within primary care. Primary Health Care Research & Development, 17(6), 536-548.
• Flight L & Julious SA (2016) Practical guide to sample size calculations: non-inferiority and equivalence trials. Pharmaceutical Statistics, 15(1), 80-89. View this article in WRRO
• Flight L & Julious SA (2016) Practical guide to sample size calculations: superiority trials. Pharmaceutical Statistics, 15(1), 75-79. View this article in WRRO
• Flight L & Julious SA (2016) Practical guide to sample size calculations: an introduction. Pharmaceutical Statistics, 15(1), 68-74. View this article in WRRO
• Palmer R, Cooper C, Enderby P, Brady M, Julious S, Bowen A & Latimer N (2015) Clinical and cost effectiveness of computer treatment for aphasia post stroke (Big CACTUS): study protocol for a randomised controlled trial. Trials, 16(1). View this article in WRRO
• Cameron D, Norman P, Epton T, Sheeran P, Harris PR, Webb TL, Julious SA, Brennan A, Thomas C, Petroczi A , Naughton D et al (2015) A theory-based online health behaviour intervention for new university students (U@Uni:LifeGuide): Results from a repeat randomized controlled trial. Trials, 16. View this article in WRRO
• Dimairo M, Boote J, Julious SA, Nicholl JP & Todd S (2015) Missing steps in a staircase: a qualitative study of the perspectives of key stakeholders on the use of adaptive designs in confirmatory trials. Trials, 16(1). View this article in WRRO
• Horspool MJ, Julious SA, Mooney C, May R, Sully B & Smithson WH (2015) Preventing and Lessening Exacerbations of Asthma in School-aged children Associated with a New Term (PLEASANT): Recruiting Primary Care Research Sites–the PLEASANT experience. npj Primary Care Respiratory Medicine, 25(1). View this article in WRRO
• Jackson L, Cohen J, Sully B & Julious S (2015) NOURISH, Nutritional OUtcomes from a Randomised Investigation of Intradialytic oral nutritional Supplements in patients receiving Haemodialysis: a pilot randomised controlled trial. Pilot and Feasibility Studies, 1(11). View this article in WRRO
• Flight L & Julious SA (2015) The disagreeable behaviour of the kappa statistic. Pharmaceutical Statistics, 14(1), 74-78.
• Dimairo M, Julious SA, Todd S, Nicholl JP & Boote J (2015) Cross-sector surveys assessing perceptions of key stakeholders towards barriers, concerns and facilitators to the appropriate use of adaptive designs in confirmatory trials. Trials, 16(1). View this article in WRRO
• Julious SA & Walters SJ (2014) Estimating effect sizes for health-related quality of life outcomes.. Stat Methods Med Res, 23(5), 430-439.
• Clayton S, Apperley E, Hannon F, Karia A, Baxter V & Julious SA (2014) A survey of birth order status of students studying for medical degree at the University of Sheffield. JRSM Open, 5(9), 205427041453332-205427041453332. View this article in WRRO
• Epton T, Norman P, Dadzie A-S, Harris PR, Webb TL, Sheeran P, Julious SA, Ciravegna F, Brennan A, Meier PS , Naughton D et al (2014) A theory-based online health behaviour intervention for new university students (U@Uni): Results from a randomised controlled trial. Acta Veterinaria Scandinavica, 563-563. View this article in WRRO
• Sully BG, Julious SA & Nicholl J (2014) An investigation of the impact of futility analysis in publicly funded trials. Acta Veterinaria Scandinavica, 61-61. View this article in WRRO
• Lee EC, Whitehead AL, Jacques RM & Julious SA (2014) The statistical interpretation of pilot trials: should significance thresholds be reconsidered?. BMC Med Res Methodol, 14, 41. View this article in WRRO
• Glasziou P, Altman DG, Bossuyt P, Boutron I, Clarke M, Julious S, Michie S, Moher D & Wager E (2014) Reducing waste from incomplete or unusable reports of biomedical research.. Lancet, 383(9913), 267-276.
• Crisp E & Julious SA (2014) The analysis of the use of 'unascertained' for sudden unexpected deaths in infancy from 1988 to 2010. Archives of Disease in Childhood, 99(3), 300-301.
• Julious S & Horspool M (2013) Preventing and lessening exacerbations of asthma in school age children associated with a new term: pleasant. Trials, 14(S1).
• Horspool MJ, Julious SA, Boote J, Bradburn MJ, Cooper CL, Davis S, Elphick H, Norman P, Smithson WH & vanStaa T (2013) Preventing and lessening exacerbations of asthma in school-age children associated with a new term (PLEASANT): Study protocol for a cluster randomised control trial. Trials, 14(1). View this article in WRRO
• Norman P, Epton T, Dadzie A-S, Sheeran P, Harris P, Webb T, Ciravegna F, Julious S, Brennan A, Meier P , Kruger J et al (2013) A theory-based online intervention to promote health behaviour in new university students: One-month follow-up data. PSYCHOLOGY & HEALTH, 28, 132-132.
• Sully BGO, Julious SA & Nicholl J (2013) A reinvestigation of recruitment to randomised, controlled, multicenter trials: a review of trials funded by two UK funding agencies.. Trials, 14, 166. View this article in WRRO
• Julious SA (2013) Meta-analysis in clinical research.. Stat Methods Med Res, 22(2), 115-116.
• Billingham SAM, Whitehead AL & Julious SA (2013) An audit of sample sizes for pilot and feasibility trials being undertaken in the United Kingdom registered in the United Kingdom Clinical Research Network database.. BMC Med Res Methodol, 13, 104. View this article in WRRO
• Epton T, Norman P, Sheeran P, Harris PR, Webb TL, Ciravegna F, Brennan A, Meier P, Julious SA, Naughton D , Petroczi A et al (2013) A theory-based online health behavior intervention for new university students: study protocol.. BMC Public Health, 13, 107. View this article in WRRO
• Julious SA, Dimairo M, Stallard N, Glimm E, Bretz F, Gallo P, Minas G, Aston JAD, Vandemeulebroecke M, Posch M , Gilmour S et al (2013) Discussion on the paper by Hampson and Jennison. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY, 75(1), 40-54.
• Julious SA, Jain R & Mason S (2013) Erratum: Environmental triggers of hospital admissions for school-age children with asthma in two British cities (Emergency Medical Journal (2012) 29, (844-845) DOI: 10.1136/emj.2011.114546). Emergency Medicine Journal, 30(1), 84.
• Julious SA (2013) Efficacy and suicidal risk for antidepressants in paediatric and adolescent patients.. Stat Methods Med Res, 22(2), 190-218.
• Jackson L, Sully B, Cohen J & Julious S (2013) Nutritional outcomes from a randomised investigation of intradialytic oral nutritional supplements in patients receiving haemodialysis, (NOURISH): a protocol for a pilot randomised controlled trial.. Springerplus, 2, 515. View this article in WRRO
• Julious SA, Jain R & Mason S (2012) Environmental triggers of hospital admissions for school-age children with asthma in two British cities.. Emerg Med J, 29(10), 844-845.
• Palmer R, Enderby P, Cooper C, Latimer N, Julious S, Paterson G, Dimairo M, Dixon S, Mortley J, Hilton R , Delaney A et al (2012) Computer therapy compared with usual care for people with long-standing aphasia poststroke: a pilot randomized controlled trial.. Stroke, 43(7), 1904-1911.
• Julious SA & Campbell MJ (2012) Tutorial in biostatistics: Sample sizes for parallel group clinical trials with binary data. Statistics in Medicine, 31(24), 2904-2936. View this article in WRRO
• Julious SA & McIntyre NE (2012) Sample sizes for trials involving multiple correlated must-win comparisons.. Pharm Stat, 11(2), 177-185.
• Sutton L, Julious SA & Goodacre SW (2012) Influence of adaptive analysis on unnecessary patient recruitment: reanalysis of the RATPAC trial.. Ann Emerg Med, 60(4), 442-8.e1.
• Lai J, Julious S, Mason S & Freeman J (2012) A retrospective case-control study investigating the association between pollutant exposures and childhood asthma. WIT Transactions on Ecology and the Environment, 157, 469-478.
• Julious SA & Whitehead A (2012) Investigating the assumption of homogeneity of treatment effects in clinical studies with application to meta-analysis. Pharmaceutical Statistics, 11(1), 49-56.
• Collinson P, Goodacre S, Gaze D, Gray A & RATPAC Research Team (2012) Very early diagnosis of chest pain by point-of-care testing: comparison of the diagnostic efficiency of a panel of cardiac biomarkers compared with troponin measurement alone in the RATPAC trial.. Heart, 98(4), 312-318.
• Bradburn M, Goodacre SW, Fitzgerald P, Coats T, Gray A, Hassan T, Humphrey J, Kendall J, Smith J, Collinson P & RATPAC Research Team (2012) Interhospital variation in the RATPAC trial (Randomised Assessment of Treatment using Panel Assay of Cardiac markers).. Emerg Med J, 29(3), 233-238.
• Julious SA (2012) Seven useful designs.. Pharm Stat, 11(1), 24-31.
• Julious SA (2011) The ABC of non-inferiority margin setting: an investigation of approaches.. Trials, 12 Suppl 1, A34.
• Julious SA (2011) Statistical issues in drug development.. Stat Methods Med Res, 20(6), 577-578.
• Julious SA, Campbell MJ, Bianchi SM & Murray-Thomas T (2011) Seasonality of medical contacts in school-aged children with asthma: association with school holidays.. Public Health, 125(11), 769-776.
• Lai J, Mason S, Burke D, Julious SA & Freeman JV (2011) 027 Paediatric emergency department attendances between 2000 and 2009: trends in a large UK Children's Hospital. Emergency Medicine Journal, 28(Suppl 1), A12-A12.
• Julious SA (2011) The ABC of non-inferiority margin setting from indirect comparisons.. Pharm Stat, 10(5), 448-453. View this article in WRRO
• Julious SA, Jain R & Mason S (2011) Environmental triggers of hospital admissions for school-age children with asthma in two British cities.. Emerg Med J.
• Parker SG, Oliver P, Pennington M, Bond J, Jagger C, Enderby P, Curless R, Vanoli A, Fryer K, Julious S , John A et al (2011) Rehabilitation of older patients: day hospital compared with rehabilitation at home. Clinical outcomes.. Age Ageing, 40(5), 557-562.
• Fitzgerald P, Goodacre SW, Cross E & Dixon S (2011) Cost-effectiveness of point-of-care biomarker assessment for suspected myocardial infarction: the randomized assessment of treatment using panel Assay of cardiac markers (RATPAC) trial.. Acad Emerg Med, 18(5), 488-495.
• Julious SA (2011) Time to end the non-inferiority complex?. Pharmaceutical Statistics, 10(5), 393-394.
• Julious S (2011) Bioequivalence studies in drug development methods and applications Hauschke D, Steinijans V, Pigeot I (2007) Wiley, Chichester, England, www.wiley.com; $110.00, £61.95. Pharmaceutical Statistics.
• Julious SA, Pyke S & Hughes S (2011) Industry sponsored trials Best practice for statisticians in industry sponsored trials. BRIT MED J, 342.
• O'Kelly M, Julious SA, Pyke S, Day S, Todd S, Seldrup J & Matcham J (2011) Making available information from studies sponsored by the pharmaceutical industry: some current practices.. Pharm Stat, 10(1), 60-69.
• Pyke S, Julious SA, Day S, O'Kelly M, Todd S, Matcham J & Seldrup J (2011) The potential for bias in reporting of industry-sponsored clinical trials.. Pharm Stat, 10(1), 74-79.
• Julious SA & Owen RJ (2011) A comparison of methods for sample size estimation for non-inferiority studies with binary outcomes.. Stat Methods Med Res, 20(6), 595-612.
• Goodacre SW, Bradburn M, Cross E, Collinson P, Gray A, Hall AS & RATPAC Research Team (2011) The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department.. Heart, 97(3), 190-196.
• Senn S, Rolfe K & Julious SA (2011) Investigating variability in patient response to treatment--a case study from a replicate cross-over study.. Stat Methods Med Res, 20(6), 657-666.
• Matcham J, Julious S, Pyke S, O'Kelly M, Todd S, Seldrup J & Day S (2011) Proposed best practice for statisticians in the reporting and publication of pharmaceutical industry-sponsored clinical trials.. Pharm Stat, 10(1), 70-73.
• Senn S & Julious S (2009) Measurement in clinical trials: a neglected issue for statisticians?. Stat Med, 28(26), 3189-3209.
• Senn S & Julious S (2009) Authors' Rejoinder to Commentaries on 'Measurement in clinical trials: A neglected issue for statisticians?'. Statistics in Medicine, 28(26), 3223-3225.
• Parker SG, Oliver P, Pennington M, Bond J, Jagger C, Enderby PM, Curless R, Chater T, Vanoli A, Fryer K , Cooper C et al (2009) Rehabilitation of older patients: day hospital compared with rehabilitation at home. A randomised controlled trial.. Health technology assessment (Winchester, England), 13(39).
• Julious SA & Mullee MA (2008) Issues with using baseline in last observation carried forward analysis.. Pharm Stat, 7(2), 142-146.
• Robinson CN, van Aswegen A, Julious SA, Nunan TO, Thomson WH, Tindale WB, Tout DA & Underwood SR (2008) The relationship between administered radiopharmaceutical activity in myocardial perfusion scintigraphy and imaging outcome.. Eur J Nucl Med Mol Imaging, 35(2), 329-335.
• Julious SA & Wang SJ (2008) How Biased Are Indirect Comparisons, Particularly When Comparisons Are Made Over Time in Controlled Trials?. DRUG INF J, 42(6), 625-633.
• Julious SA & George S (2007) Are hospital league tables calculated correctly? A commentary - Reply. PUBLIC HEALTH, 121(12), 907-908.
• Julious SA & George S (2007) Are hospital league tables calculated correctly?. Public Health, 121(12), 902-904.
• Julious SA, Campbell MJ & Walters SJ (2007) Predicting where future means will lie based on the results of the current trial.. Contemp Clin Trials, 28(4), 352-357.
• Julious SA, Osman LM & Jiwa M (2007) Increases in asthma hospital admissions associated with the end of the summer vacation for school-age children with asthma in two cities from England and Scotland.. Public Health, 121(6), 482-484.
• Julious S (2007) A personal perspective on the Royal Statistical Society report of the working party on statistical issues in first-in-man studies.. Pharm Stat, 6(2), 75-78.
• Patterson SD, Carroll K & Julious S (2007) Literature review October–December 2006. Pharmaceutical Statistics, 6(1), 67-68.
• Julious SA, Nicholl J & George S (2006) Why do we continue to use standardised mortality ratios for small area comparisons (vol 23, pg 40, 2001). J PUBLIC HEALTH, 28(4), 399-399.
• George S & Julious S (2006) Are we getting what we pay for?. Public Health, 120(11), 1013-1019.
• Julious SA & Wang SJ (2006) Making an impact. PHARM STAT, 5(3), 157-158.
• Julious S (2006) Data monitoring clinical trials: a case studies approach DeMets DL, Furberg CD, Friedman LM (eds) (2006)ISBN 0387203303; 374 pages; £28.50, ??36.95, $49.95 Springer;. Pharmaceutical Statistics, 5(2), 151-152.
• Julious SA & Wang SJ (2006) Adapt to survive or adapt to succeed?. PHARM STAT, 5(2), 81-81.
• Julious SA, Nicholl J & George S (2006) Erratum: Why do we continue to use standardised mortality ratios for small area comparisons (Journal of Public Health (2001) 23:1 (40-46)). Journal of Public Health, 28(4), 399.
• Furlong L, Julious SA & Wang SJ (2006) Lots achieved, lots more to do. PHARM STAT, 5(1), 1-3.
• Julious SA & Owen RJ (2006) Sample size calculations for clinical studies allowing for uncertainty about the variance.. Pharm Stat, 5(1), 29-37.
• Julious SA (2005) Two-sided confidence intervals for the single proportion: comparison of seven methods by Robert G. Newcombe, Statistics in Medicine 1998; 17:857-872.. Stat Med, 24(21), 3383-3384.
• Julious SA (2005) Issues with number needed to treat.. Stat Med, 24(20), 3233-3235.
• Chuang-Stein C, Furlong L & Julious S (2005) Untitled. PHARM STAT, 4(4), 231-232.
• Julious SA (2005) Sample size of 12 per group rule of thumb for a pilot study. PHARM STAT, 4(4), 287-291.
• Chuang-Stein C, Furlong L & Julious SA (2005) Brainstorming with advisory board members. PHARM STAT, 4(3), 153-154.
• Chuang-Stein C, Furlong L & Julious S (2005) Editorial. Pharmaceutical Statistics, 4(1), 1-2.
• Chuang-Stein C, Furlong L & Julious SA (2005) Editorial. Pharmaceutical Statistics, 4(2), 85-86.
• Julious SA & Swank DJ (2005) Moving statistics beyond the individual clinical trial: applying decision science to optimize a clinical development plan. PHARM STAT, 4(1), 37-46.
• Julious SA (2005) Why do we use pooled variance analysis of variance?. PHARM STAT, 4(1), 3-5.
• Julious S (2004) Meta-analysis of controlled clinical trialsWhitehead A (2002)ISBN 0471983705; 352 pages; £55.00; 82.50; $95.00 Wiley; http://www.wileyeurope.com/WileyCDA/WileyTitle/productCd-0471983705.html. Pharmaceutical Statistics, 3(4), 305-305.
• Julious SA (2004) Designing clinical trials with uncertain estimates of variability. PHARM STAT, 3(4), 261-268.
• Julious SA (2004) Using confidence intervals around individual means to assess statistical significance between two means. PHARM STAT, 3(3), 217-222.
• Julious SA & Patterson SD (2004) Sample sizes for estimation in clinical research. PHARM STAT, 3(3), 213-215.
• Julious SA (2004) Sample sizes for clinical trials with normal data.. Stat Med, 23(12), 1921-1986. View this article in WRRO
• Julious S (2004) Sample size redetermination for repeated measures studies.. Biometrics, 60(1), 284.
• Julious S (2004) Letter to the Editors. Biometrics, 60(1), 284-284.
• Julious SA (2004) A Manager's Guide to the Design and Conduct of Clinical Trials. Phillip I. Good(ed.), Wiley, Chichester, U.K., 2002. No. of pages: xiv+ 228. ISBN: 0471226157. Statistics in Medicine, 23(3), 529-530.
• Julious S (2004) Sample size redetermination for repeated measures studies.. Biometrics, 60(1).
• Julious S & Zariffa NV (2002) The ABC of pharmaceutical trial design: some basic principles. Pharmaceutical Statistics, 1(1), 45-53.
• Campbell MJ, Julious SA, Peterson CK & Tobias A (2001) Atmospheric pressure and sudden infant death syndrome in Cook County, Chicago.. Paediatr Perinat Epidemiol, 15(3), 287-289.
• Julious SA, Nicholl J & George S (2001) Why do we continue to use standardized mortality ratios for small area comparisons?. J Public Health Med, 23(1), 40-46.
• Julious SA (2001) Inference and estimation in a changepoint regression problem. J ROY STAT SOC D-STA, 50, 51-61.
• Woodcock AJ, Julious SA, Kinmonth AL, Campbell MJ & Diabetes Care From Diagnosis Group (2001) Problems with the performance of the SF-36 among people with type 2 diabetes in general practice.. Qual Life Res, 10(8), 661-670.
• Julious SA (2000) Repeated measures in clinical trials: analysis using mean summary statistics and its implications for design by L. Frison and S.J. Pocock, Statistics in Medicine 1992; 12: 1685-1704.. Stat Med, 19(22), 3133-3135.
• Julious SA, Campbell MJ, Walker SJ, George SL & Machin D (2000) Sample sizes for cancer trials where Health Related Quality of Life is the primary outcome.. Br J Cancer, 83(7), 959-963. View this article in WRRO
• Lewis JA, Spiegelhalter DJ, Ashby D, Keene O, Racine-Poon A, Atkinson AC, Grieve AP, Morgan D, Nelder JA, Preece DA , Evans SJW et al (2000) Consensus and controversy in pharmaceutical statistics - Discussion. J ROY STAT SOC D-STA, 49, 156-176.
• Julious SA & Debarnot CA (2000) Why are pharmacokinetic data summarized by arithmetic means?. J Biopharm Stat, 10(1), 55-71.
• Julious SA & Mullee MA (2000) Crude rates of outcome.. Br J Surg, 87(1), 8-9.
• McColm JA, Peck RW, Koch KM, Julious S, Collyer SM & Hulbert R (1999) A study to investigate the tolerability, pharmacokinetics and effects on blood pressure, heart rate and substance p-induced wheal and flare response of single, oral doses of 4991W93 in healthy volunteers.. CEPHALALGIA, 19(4), 406-406.
• McColm JA, Peck RW, Koch KM, Julious S, Collyer SM & Hulbert R (1999) A study to investigate the tolerability, pharmacokinetics and effects on blood pressure of single intravenous doses of 4991W93 in healthy volunteers.. CEPHALALGIA, 19(4), 406-406.
• Julious SA, Campbell MJ & Altman DG (1999) Estimating sample sizes for continuous, binary, and ordinal outcomes in paired comparisons: practical hints.. J Biopharm Stat, 9(2), 241-251.
• Julious SA & Campbell MJ (1998) Sample size calculations for paired or matched ordinal data.. Stat Med, 17(14), 1635-1642.
• Cunningham AF, Johnston SL, Julious SA, Lampe FC & Ward ME (1998) Chronic Chlamydia pneumoniae infection and asthma exacerbations in children.. Eur Respir J, 11(2), 345-349.
• Gibbard NL, Campbell MJ, George S & Julious SA (1997) Measures of quality of life trends over time. QUAL LIFE RES, 6(7-8), 123-123.
• al-Sadi M, Newman B & Julious SA (1997) Acupuncture in the prevention of postoperative nausea and vomiting.. Anaesthesia, 52(7), 658-661.
• Nott MR, Jameson PM & Julious SA (1997) Diazepam for relief of irrigation pain after transurethral resection of the prostate.. Eur J Anaesthesiol, 14(2), 197-200.
• Julious SA, George S, Machin D & Stephens RJ (1997) Sample sizes for randomized trials measuring quality of life in cancer patients.. Qual Life Res, 6(2), 109-117.
• Julious SA (1997) There is still seasonality in sudden infant death syndrome in England and Wales.. J Epidemiol Community Health, 51(1), 101-102.
• Challiner Y, Julious S, Watson R & Philp I (1996) Quality of care, quality of life and the relationship between them in long-term care institutions for the elderly. INT J GERIATR PSYCH, 11(10), 883-888.
• Rew DA, Karkera R, Mullee MA, Julious SA & Wilson GD (1996) The flow cytometric analysis of total p53 protein content and proliferation indices in colorectal cancer, in relation to clinical outcome.. Eur J Surg Oncol, 22(5), 508-515.
• Campbell MJ, Julious SA & George SL (1996) Estimating sample sizes for studies using the SF-36 health survey - Reply. J EPIDEMIOL COMMUN H, 50(4), 473-474.
• JULIOUS SA & CAMPBELL MJ (1996) LETTER TO THE EDITOR: SAMPLE SIZES CALCULATIONS FOR ORDERED CATEGORICAL DATA by J. Whitehead,Statistics in Medicine, 12, 2257-2272 (1993).. Statistics in Medicine, 15(10), 1065-1066.
• Julious SA & Campbell MJ (1996) Sample sizes calculations for ordered categorical data.. STAT MED, 15(10), 1065-1066.
• CUNNINGHAM A, JOHNSTON S, JULIOUS S, LAMPE F & WARD M (1996) 492 Association between nasal sIGA to chronic Chlamydia pneumoniae infection and asthma exacerbations in children. Journal of Allergy and Clinical Immunology, 97(1), 305-305.
• Cunningham A, Johnston SL, Julious SA, Lampe FC & Ward ME (1996) Association between nasal sIGA to chronic Chlamydia pneumoniae infection and asthma exacerbations in children.. J ALLERGY CLIN IMMUN, 97(1), 492-492.
• Julious SA, George S & Campbell MJ (1995) Sample sizes for studies using the short form 36 (SF-36). J Epidemiol Community Health, 49(6), 642-644.
• Campbell MJ, Julious SA & Altman DG (1995) Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons.. BMJ, 311(7013), 1145-1148.
• JULIOUS SA, CAMPBELL MJ & GEORGE S (1995) STATISTICS WOULD MAKE STALIN PROUD. BRIT MED J, 311(7002), 455-455.
• Mullee MA, Pickering RM, Lampe FC & Julious SA (1995) Statisticians should be coauthors. BMJ, 310(6983), 869-869.
• BRYANT TN & JULIOUS SA (1995) MULTI-VARIATE STATISTICAL-PACKAGE-PLUS VERSION-2.1. COMPUT APPL BIOSCI, 11(2), 227-228.
• Mullee MA, Lampe FC, Pickering RM & Julious SA (1995) Criteria for authorship. Statisticians should be co-authors.. BMJ, 310(6983), 869.
• Bryant TN & Julious SA (1995) CABIOS SOFTWARE REVIEW: Multi-Variate Statistical Package Plus version 2.1. Bioinformatics, 11(2), 227-228.
• MULLEE MA & JULIOUS SA (1995) CONFOUNDING AND SIMPSONS PARADOX - MULTIPLE-REGRESSION WOULD CONFOUND THE CLINICIAN - REPLY. BRIT MED J, 310(6975), 329-329.
• Sarcristan JA & Hernandez JM (1995) Criteria for authorship. BMJ, 310(6983), 869.
• Pollock AM, Vickers N, Charlton J, Dunnell K, Julious SA, Campbell MJ & George S (1995) Measuring NHS activity [6]. British Medical Journal, 311(7002), 454-455.
• Charig CR (1995) Confounding and Simpson's paradox. BMJ, 310(6975), 329.
• Julious SA & Mullee MA (1994) Confounding and Simpson's paradox.. BMJ, 309(6967), 1480-1481.
• Walters DP, Gatling W, Houston AC, Mullee MA, Julious SA & Hill RD (1994) Mortality in diabetic subjects: an eleven-year follow-up of a community-based population.. Diabet Med, 11(10), 968-973.
• CHALLINER Y, WATSON R, JULIOUS S & PHILP I (1994) A POSTAL SURVEY OF THE QUALITY OF LONG-TERM INSTITUTIONAL CARE. INT J GERIATR PSYCH, 9(8), 619-625.
• Rickenbach MA & Julious SA (1994) Assessing fullness of asthma patients' aerosol inhalers.. Br J Gen Pract, 44(384), 317-318.
• Corder AP, Cross M, Julious SA, Mullee MA & Taylor I (1994) The timing of breast cancer surgery within the menstrual cycle.. Postgrad Med J, 70(822), 281-284.
• Challiner YC, Jarrett D, Hayward MJ, al-Jubouri MA & Julious SA (1994) A comparison of intravenous and subcutaneous hydration in elderly acute stroke patients.. Postgrad Med J, 70(821), 195-197.
• Campbell MJ & Julious SA (1994) Statistics in Medicine: citations of papers in the first ten years.. Stat Med, 13(1), 3-10.
• Challiner YCM, Watson R, Julious S & Philip I (1993) A Postal Survey of the Quality of Long-Term Institutional Care. Age and Ageing, 22(suppl 3), P6-P7.
• Sullivan PM, Luff AJ, Julious SA & Canning CR (1993) Patient satisfaction following vitreoretinal surgery.. Eye (Lond), 7 ( Pt 3), 433-435.
• Challiner Y, Hayward M, Al-Jubouri M & Julious S (1992) Is Subcutaneous Rehydration as Effective as Intravenous in Elderly Stroke Patients?. Age and Ageing, 21(suppl 2), P17-P17.
• Chatters R, Hawksworth O, Julious S & Cook A () Correction: The development of a set of key points to aid clinicians and researchers in designing and conducting n-of-1 trials. Trials, 25(1).
• Niederberger M, Schifano J, Deckert S, Hirt J, Homberg A, Köberich S, Kuhn R, Rommel A & Sonnberger M () Delphi studies in social and health sciences—Recommendations for an interdisciplinary standardized reporting (DELPHISTAR). Results of a Delphi study. PLOS ONE, 19(8), e0304651-e0304651.
• Hawksworth O, Chatters R, Julious S, Cook A, Biggs K, Solaiman K, Quah MCH & Cheong SC () A methodological review of randomised n-of-1 trials. Trials, 25(1).
• Totton N, Julious SA, Coates E, Hughes DA, Cook JA, Biggs K, Hewitt C, Day S & Cook A () Appropriate design and reporting of superiority, equivalence and non-inferiority clinical trials incorporating a benefit–risk assessment: the BRAINS study including expert workshop. Health Technology Assessment, 1-58.
• Junqueira DR, Zorzela L, Golder S, Loke Y, Gagnier JJ, Julious SA, Li T, Mayo-Wilson E, Pham B, Phillips R , Santaguida P et al () CONSORT Harms 2022 statement, explanation, and elaboration: updated guideline for the reporting of harms in randomised trials. BMJ, e073725-e073725.
• Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Young T, Rajbhandari S, Sharma S, Rayman G, Gouni R , Alam U et al () Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT. Health Technology Assessment, 26(39), 1-100.
• Han O, Tan HW, Julious S, Sutton L, Jacques R, Lee E, Lewis J & Walters S () A descriptive study of samples sizes used in agreement studies published in the PubMed repository. BMC Medical Research Methodology, 22(1).
• Bell ML, Whitehead AL & Julious SA () Guidance for using pilot studies to inform the design of intervention trials with continuous outcomes. Clinical Epidemiology, Volume 10, 153-157. View this article in WRRO
• Stevely A, Dimairo M, Todd S, Julious SA, Nicholl J, Hind D & Cooper CL () An Investigation of the Shortcomings of the CONSORT 2010 Statement for the Reporting of Group Sequential Randomised Controlled Trials: A Methodological Systematic Review. PLOS ONE, 10(11), e0141104-e0141104. View this article in WRRO

Chapters

• Rothwell J, Cooper C, Julious S & Campbell M (2021) Background to Sample Size Calculations, Handbook of Statistical Methods for Randomized Controlled Trials (pp. 243-274). Chapman and Hall/CRC
• Julious SA, Tan SB & Machin D (2010) Bayesian and Frequentist Methods, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 113-124).
• Julious SA, Tan SB & Machin D (2010) Go/No-Go Criteria, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 231-244).
• Julious SA, Tan SB & Machin D (2010) Phase II Trials with Toxic Therapies, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 211-222).
• Julious SA, Tan SB & Machin D (2010) Interpreting and Applying Early Phase Trial Results, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 223-230).
• Julious SA, Tan SB & Machin D (2010) Dose-Response Studies, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 197-210).
• Julious SA, Tan SB & Machin D (2010) Phase II Trials: General Issues, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 186-196).
• Julious SA, Tan SB & Machin D (2010) Other Phase I Trials, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 169-185).
• Julious SA, Tan SB & Machin D (2010) Bioequivalence Studies, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 139-167).
• Julious SA, Tan SB & Machin D (2010) First-Time-into-New-Population Studies, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 125-138).
• Julious SA, Tan SB & Machin D (2010) First Time into Man, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 87-111).
• Julious SA, Tan SB & Machin D (2010) Introduction to Pharmacokinetics, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 13-35).
• Julious SA, Tan SB & Machin D (2010) Multi-period Crossover Trials, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 71-85).
• Julious SA, Tan SB & Machin D (2010) Sample Size Calculations for Clinical Trials, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 37-53).
• Julious SA, Tan SB & Machin D (2010) Crossover Trial Basics, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 54-69).
• Julious SA, Tan SB & Machin D (2010) Early Phase Trials, INTRODUCTION TO STATISTICS IN EARLY PHASE TRIALS (pp. 1-+).
• Whitehead AL & Julious SA () Pilot Studies in Clinical Research (pp. 1-8). Wiley View this article in WRRO
• Campbell MJ, Julious SA, Walker SJ, George SL & Machin D () A Review of the Use of the Main Quality of Life Measures, and Sample Size Determination for Quality of Life Measures, Particularly in Cancer Clinical Trials, The Advanced Handbook of Methods in Evidence Based Healthcare (pp. 338-351). SAGE Publications Ltd

Conference proceedings papers

• Alyami R, Oliver P, Simpson R & Julious S (2023) Preventing Summer Holiday Drop in Prescription Uptake for School-Age Children with Asthma: A Pragmatic Cluster Randomized Controlled Trial of a Letter to GP Practices (TRAINS). General practice and primary care
• (2020) 41st Annual Meeting of the Society for Medical Decision Making Portland, Oregon, October 20–23, 2019. Medical Decision Making, Vol. 40(1) (pp E1-E379)
• Flight L, Julious S, Brennan A & Todd S (2020) METHODS FOR CHOOSING THE BEST DESIGN OF A CLINICAL TRIAL: IMPLEMENTING EXPECTED VALUE OF SAMPLE INFORMATION AND ADJUSTING FOR BIAS INDUCED BY A GROUP SEQUENTIAL DESIGN. MEDICAL DECISION MAKING, Vol. 40(1) (pp E188-E189)
• Flight L, Hind D, Julious S, Brennan A & Todd S (2019) Considerations concerning the use of health economics in the design and analysis of adaptive clinical trials - a qualitative study. Trials, Vol. 20(Supplement 1) (pp 109-109). Brighton, UK, 6 October 2019 - 9 October 2019. View this article in WRRO
• Totton N, Julious S, Hughes D & Cook J (2019) MRC-NIHR Methodology guideline development on utilising benefit-risk assessments within clinical trials. Trials, Vol. 20(Supplement 1) (pp 93-93). Brighton, UK, 6 October 2019 - 9 October 2019. View this article in WRRO
• Dimairo M, Pallmann P, Wason J, Todd S, Jaki T, Julious SA, Mander AP, Weir CJ, Koenig F, Walton MK , Nicholl JP et al (2019) Introducing the adaptive designs CONSORT extension (ACE) statement to improve reporting of randomised trials that use an adaptive design. Trials, Vol. 20(Supplement 1) (pp 2-3). Brighton, UK, 6 October 2019 - 9 October 2019. View this article in WRRO
• Buelo A, Mclean S, Flores-Kim J, Julious S, Shields M, Paton J, Henderson J, Bush A & Pinnock H (2017) S62 Identifying the child (5–12 years) with asthma at increased risk of attacks: the at-risk child with asthma (arc) systematic review. Paediatric asthma: big and real world data View this article in WRRO
• Buelo A, Mclean S, Flores-Kim J, Julious S, Shields M, Paton J, Henderson J & Pinnock H (2017) A systematic review to identify and weight indicators of risk of asthma exacerbations in children aged 5-12. General Practice and Primary Care
• Dimairo M, Todd S, Julious S, Jaki T, Wason J, Hind D, Mander A, Weir C, Koenig F, Altman D , Hamasaki T et al (2017) Journeying through the development of an adaptive designs reporting guidance: findings from Delphi process. CEN ISBS Vienna 2017 (pp 94-94), 28 August 2017 - 1 September 2017.
• Dimairo M, Todd S, Julious S, Jaki T, Wason J, Mander A, Hind D, Weir C, Koenig F, Altman D , Nicholl J et al (2017) Journeying through the development of an adaptive designs reporting guidance: preliminary findings. Evidence Live 2017 (pp 42-43), 21 June 2017 - 22 June 2017.
• Simpson R, Julious SA & Baird WO (2017) An investigation of the factors which influence children with asthma having unscheduled medical contacts around the start of the new school year in England and Wales: a mixed methods study. TRIALS, Vol. 18
• Rothwell J, Julious SA & Cooper C (2017) Quantifying effect sizes in clinical trials. TRIALS, Vol. 18
• Elphick H, Horspool M, Davis S, Bradburn M, Norman P, Shephard N, Cooper C, Smithson WH, Boote J, Loban A , Franklin M et al (2016) LATE-BREAKING ABSTRACT: PLEASANT: Preventing and lessening exacerbations of asthma in school-age children associated with a new term. 1.6 General Practice and Primary Care
• Dimairo M, Stevely A, Todd S, Julious S, Nicholl J, Hind D & Cooper C (2015) Investigation of the shortcomings of the consort 2010 statement for the reporting of group sequential randomised controlled trials. Trials, Vol. 16(S2) View this article in WRRO
• Dimairo M, Julious S, Todd S & Nicholl J (2015) Meandering journey towards routine trial adaptation: survey results on barriers to use of adaptive designs in confirmatory trials. Trials, Vol. 16(S2) View this article in WRRO
• Dimairo M, Stevely A, Julious S, Todd S, Cooper C, Hind D & Nicholl J (2015) Differential reporting of group sequential RCTs: shortcomings ofthe CONSORT 2010 statement. CPS 11: Group Sequential Methods and Interim Analysis. ARLINGTON, VIRGINIA, USA, 17 May 2015 - 20 May 2015.
• McClung C, Quessy S, Julious S, Segreti A, Blum D & Kline GS (2004) Placebo response rates and geographic location in COX-2 inhibitor trials of rheumatoid arthritis (RA) and osteoarthritis (OA): A meta-analysis.. ARTHRITIS AND RHEUMATISM, Vol. 50(9) (pp S555-S555)
• Cunningham A, Johnson S, Julious SA, Sillis M & Ward ME () The role of Chlamydia pneumoniae and other pathogens in acute episodes of asthma in children. Proceedings of the 8th International Symposium on Human Chlamydial Infections (pp 480-483). 1994

Reports

• Wilson-Smith E, Smith CD, Julious S, Flight L & Reynolds J (2015) Does Menstrual Hygiene Matter?: Investigating the Impact of a Menstrual Hygiene Program (Reusable Sanitary Pad and Menstrual Health Education) on Rural Ugandan Girls' School Absenteeism: study protocol for a cluster randomised control trial

Website content

• Dimairo M, Julious S, Bennett D & Palmer R (2018) Big CACTUS Statistical Analysis Plan v1.2 mar2018.

Posters

• Dimairo M, Todd S, Julious S, Jaki T, Wason J, Hind D, Mander A, Weir C, Koenig F, Altman D , Nicholl J et al (2017) Journeying through the development of a consensus-driven adaptive designs reporting guidance. Global Forum on Bioethics in Research. View this article in WRRO

Other

• Palmer R, Cooper C, Enderby P, Brady M, Julious S, Bowen A, Latimer N, Gossage-Worrall R, Cross E & Harrison M (2018) Big CACTUS study protocol v5.0 31may17.

Preprints

• Totton N, Julious S, Walters S & Coates E (2023) A review of UK publicly funded non-inferiority trials: Is the design more inferior than it should be?, Research Square Platform LLC.
• Salsbury J, Oakley J, Julious S & Hampson L (2023) Assurance Methods for designing a clinical trial with a delayed treatment effect, arXiv.
• Chatters R, Hawksworth L, Julious S & Cook A (2023) The development of a set of key points to aid clinicians and researchers in designing and conducting n-of-1 trials, Research Square Platform LLC.
• Hawksworth O, Chatters R, Julious SA, Cook A, Biggs K & Solaiman K (2023) A Methodological Review of Randomised n-of-1 Trials., Research Square Platform LLC.
• Alyami RA, Simpson R, Oliver P & Julious SA (2022) TRial to Assess Implementation of New research in a primary care Setting (TRAINS): study protocol for a pragmatic cluster randomised controlled trial of an educational intervention to promote asthma prescription uptake in General Practitioner Practices, Research Square.
• Han O, Tan HW, Julious S, Sutton L, Jacques R, Lee E, Lewis J & Walters S (2022) Review of samples sizes used in agreement studies published in the PubMed database, Research Square.
• Duro E, Julious PS & Ren S (2022) An Investigation of the Constancy of Effect in Cochrane Systematic Reviews in Context with the Assumptions for Non-Inferiority trials., Research Square Platform LLC.
• Flight L, Brennan A, Chick SE, Forster M, Julious S & Tharmanathan P () Value-Adaptive Clinical Trial Designs for Efficient Delivery of Research – Actions, Opportunities and Challenges for Publicly Funded Trials.
• Totton N, Julious S, Hughes D, Cook J, Biggs K, Coates L, Cook A, Hewitt C & Day S () Utilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project, Research Square Platform LLC.
• Totton N, Julious S, Hughes D, Cook J, Biggs K, Coates L, Cook A, Hewitt C & Day S () Utilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project, Research Square Platform LLC.
• Totton N, Julious S, Hughes D, Cook J, Biggs K, Coates L, Cook A, Hewitt C & Day S () Utilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project, Research Square Platform LLC.
• Wilson E, Smith C, Herbert E & Julious S () Investigating the Impact of a Menstrual Hygiene Program on School Absenteeism of Rural Ugandan Girls: A Delayed Cluster Randomised Control Trial.
• Cook JA, Julious SA, Sones W, Hampson LV, Hewitt C, Berlin JA, Ashby D, Emsley R, Fergusson DA, Walters SJ , Wilson ECF et al () Choosing the Target Difference (“effect size”) for a Randomised Controlled Trial - DELTA² Guidance, MDPI AG.