Nucleic acid biophysics, chemistry and structure
Our research focuses on all aspects of nucleic acid structure, chemistry and function employing state of the art technologies and approaches.
The structure and chemistry of nucleic acids is fundamental to their function, from the DNA double helix discovered by Watson and Crick to the intricate secondary and tertiary structures adopted by RNA molecules. However, nucleic acids are not just static molecules, and modern biophysical, single molecule, structural and computational approaches now allow us to view how nucleic acids move with unprecedented levels of detail. They also allow us to better understand how these processes are affected by mutations and by the molecules that bind to and interact with nucleic acids.
Our research focuses on all aspects of nucleic acid structure, chemistry and function employing state of the art technologies and approaches. Our goal is to generate a better understanding of how nucleic acids function at the molecular level.
This research theme is led by Dr Indrajit Lahiri.
