SITraN's donor-powered timeline of hope

A vision. A community. A decade of breakthroughs. See how donor support turned one Professor's ambition into a world-leading neuroscience research hub.

Architect's design of the new SITraN expansion
The new expansion to SITraN will increase lab space to speed up treatments for devastating conditions like MND
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Explore how Sheffield Institute for Translational Neuroscience (SITraN) grew from an ambitious idea into a global force in neuroscience — and how your support is shaping the breakthroughs ahead.

2008–2010: Making the vision a reality 

Neuroscientist Professor Dame Pamela Shaw provided the vision, but it was Sheffield's donor community who made SITraN a reality. Gifts from individuals and organisations, as well as fundraising challenges, including sailing the Atlantic and trekking across the Antarctic, helped fund the new facility. 

2017–2020: Funding a window into the human body

Together you helped to raise £2m to fund the Sheffield Scanner. Determined fundraisers even took on a 50-mile  Big Walk challenge to help our researchers see inside the body like never before. This transformative tool has changed how we diagnose and track conditions like dementia and Parkinson’s, turning your support into real-time discovery. 

2024–2026: Expanding neuroscience research 

 Right now, building work is underway for a much-needed  expansion that will double SITraN's teaching and research capabilities. This is only happening because of donor support! Five incredible individuals and charitable trusts made gifts of over £1m. And, in total, over 27,000 gifts were made; including sponsors backing the Big Walk in 2024 and 2025. We're thrilled so many people were part of raising the £14m needed to power this transformation.

2027 and beyond:  Leading the way

Early next year, the next chapter of SITraN begins — thanks to you. This isn’t just about more space; it’s about more breakthroughs. By funding facilities for discovery research, drug screening and clinical trials you will directly accelerate new treatments. Because of your commitment, Sheffield will continue to lead the way in neuroscience research, bringing the reality of life-changing therapies one step closer. 

Pamela Shaw portrait

Over 20 years ago a lady with MND asked me what I would do with £20 million of funding for MND research. I didn’t think it was a serious question, but I described SITraN - a dedicated facility to bring together scientists, doctors and patients from all over the world under one roof with a shared ambition to improve the lives of people living with neurodegenerative diseases.

Dame Professor Pamela Shaw

Director of SITraN

SITraN in brief

  • Transforms laboratory breakthroughs into real-world treatments.
  • MND, Parkinson's, dementia, stroke and multiple sclerosis are just some of the conditions being studied.
  • Unique ‘Bench-to-bedside’ approach offers patients and their families the hope of a path toward a cure. 

Learn more about SITraN

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United in your passion for Sheffield and how it can shape the world, together you'll help bright minds thrive. 

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