SCOTI
Sheffield Clinical Oncology Trials Infrastructure (SCOTI)
Background
Before a new test or treatment can be used within the NHS for routine cancer care, it must be shown to be safe and better than the current option. This is often done through clinical trials.
Sheffield’s Clinical Trials Research Unit (CTRU) has a proven track record of running large, multi-centre clinical trials. Still, it doesn’t yet have the capacity to run many cancer trials. This means that many cancer patients across Yorkshire are disadvantaged as they don’t get a chance to get involved in locally led trials addressing regional priorities and local needs.
The £4.7M SCOTI grant funded by the Yorkshire Cancer Research Sheffield Pioneers Fund will be used to build a specialist team in Sheffield to support cancer trials.
Our aim is to offer research opportunities to more patients in Yorkshire by increasing Sheffield’s capacity and skills while focusing on local needs.
We will employ new staff with required clinical and methodological expertise and develop our existing staff through collaboration, mentoring, and training. We will also develop the CTRU’s processes and functionality needed to run cancer trials, including trial design, quality assurance, data management, and database systems.
We will work alongside our public involvement panel, cancer researchers, and our regional and community healthcare partners to determine the best ways to treat patients and collect the evidence needed to change NHS practice. To ensure our research is relevant to the region, our public involvement panel will include members from diverse backgrounds.
Project Leadership Group
Name | Role | Organisation |
|---|---|---|
| Prof Matt Hammond | Chief Investigator and CRTU Director | University of Sheffield |
Prof Stephen Walters | Chief Investigator and Professor of Medical Statistics | University of Sheffield |
Prof Deepak Parashar | Academic Lead for Oncology Trials | University of Sheffield |
Hannah Berntsson | Senior Study Manager for Oncology | University of Sheffield |
David White | Co-Applicant/Quality Assurance | University of Sheffield |
Katie Biggs | Co-Applicant/PPI & EDI | University of Sheffield |
Diana Papaioannou | Co-Applicant | University of Sheffield |
Dr Amanda Loban | Co-Applicant/CTRU Data Management | University of Sheffield |
David Hook | PPI Co-Applicant | N/A |
| Ceri Steel | PPI Collaborator | N/A |
Dr Brindley Hapuarchi | Co-Applicant | Sheffield Teaching Hospitals |
Dr Kate Fryer | Co-Applicant/PPI & EDI | University of Sheffield |
Prof Jonathan Wadsley | Co-Applicant | Sheffield Teaching Hospitals |
Prof Jim Wild | Co-Applicant | University of Sheffield |
Prof Caroline Mitchell | Co-Applicant/PPI & EDI | Keele University |
Prof Wendy Baird | Co-Applicant/CCRA | University of Sheffield |
Prof Syed Hussain | Co-Applicant/Clinician | University of Sheffield |
Prof Sarah Danson | Co-Applicant/School Director of Research | University of Sheffield |
Prof Nicholas Latimer | Co-Applicant/Methodology | University of Sheffield |
Prof Lynda Wyld | Co-Applicant/Clinician | University of Sheffield |
Prof Janet Brown | Co-Applicant/Clinician | University of Sheffield |
Prof James Catto | Co-Applicant/Clinician | University of Sheffield |
Prof Syed Ali Khurram | Co-Applicant/Clinician | University of Sheffield |
Prof Mark Strong | Dean of School | University of Sheffield |
Jessica Welburn | CTRU Assistant Manager | University of Sheffield |
Chris Turtle | CTRU Data Manager | University of Sheffield |