Professor Steve Goodacre
MB, ChB, MRCP, DipIMC, FRCEM, MSc, PhD
Population Health, School of Medicine and Population Health
Professor of Emergency Medicine
Emeritus NIHR Senior Investigator
Senior Associate Editor, Annals of Emergency Medicine
+44 114 222 0842
Full contact details
Population Health, School of Medicine and Population Health
3023
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
- Profile
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I am a clinical academic in emergency medicine and researcher in emergency care.
- Research interests
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My research interests include organisation of emergency care, economic analysis, clinical trials, and clinical risk prediction in emergency care.
Current and recent projects:
- Evaluation of NEWS2 in the initial assessment of adults attending the emergency department. Funded by the NIHR Research for Patient Benefit Programme, £148,090, November 2023 to October 2024.
- ASES: Aortic Syndrome Evidence Synthesis. Funded by the NIHR Health Technology Assessment Programme, £200,759, January 2023 to December 2023.
- The VTEAM study: Venous Thromboembolism risk Assessment Models for hospital inpatients. Funded by the NIHR Health Technology Assessment Programme, £548,794, June 2019 to May 2021.
- The PHEWS study: Pre-Hospital Early Warning for Sepsis. Funded by the NIHR Health Technology Assessment Programme, £561,164, June 2019 to May 2021.
- The PRIEST study: Pandemic Respiratory Infection Emergency System Triage. Funded by the NIHR Health Technology Assessment Programme, £795,348, August 2012 to March 2021.
Co-investigator
- EnSygN: Evidence S(heffield)ynthesis group for NIHR. Funded by the NIHR Evidence Synthesis Groups, £2,500,000, April 2023 to March 2028.
- TiLLI: Thromboprophylaxis in Lower Limb Immobilisation. Funded by the NIHR Health Technology Assessment Programme, £3,058,779 (Queen Mary University of London), September 2023 to September 2028.
- BE SURE: Building an understanding of Ethnic minority people's Service Use Relating to Emergency care for injuries, funded by NIHR Health Service & Delivery, £729,226 (Swansea University), October 2021 to October 2023
- ASPIRED: RCT of immediate enhanced ambulatory ECG monitoring versus standard monitoring in acute unexplained syncope, funded by the British Heart Foundation, £1,303,649 (Edinburgh Royal Infirmary), August 2021 to July 2025
- PRIEST (Pandemic Respiratory Infection Emergency System Triage) study for low resource settings, Bill & Melinda Gates Foundation, £98,723, July 2021 to June 2022
- Pre-alerts: Exploring the use of pre-hospital pre-alerts and their impact on patients, Ambulance Service and Emergency Department staff, funded by NIHR Health Service & Delivery Research, £555,705, April 2021 to August 2023
- IPEP: Development of a clinical decision aid for the differential diagnosis of transient loss of consciousness, funded by NIHR Research for Patient Benefit , £145,355, March 2021 to October 2022
- VTEP: Venous thromboembolism prophylaxis for women during pregnancy and after delivery, funded by NIHR Health Technology Assessment, £189,896, January 2021 to March 2022
- TARGET-CTCA: Troponin in Acute chest pain to Risk stratify and Guide EffecTive use of Computed Tomography Coronary Angiography. Funded by the British Heart Foundation, £1,115,723, August 2018 to July 2023.
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Composite outcomes in clinical prediction modeling: are we trying to predict apples and oranges?. Annals of Emergency Medicine. View this article in WRRO
- Early computed tomography coronary angiography in patients with suspected acute coronary syndrome: randomised controlled trial. BMJ: British Medical Journal, 374. View this article in WRRO
- Do not attempt cardiopulmonary resuscitation (DNACPR) decisions in people admitted with suspected COVID-19 : secondary analysis of the PRIEST observational cohort study. Resuscitation, 164, 130-138. View this article in WRRO
- Which is the best model to assess risk for venous thromboembolism in hospitalised patients?. BMJ: British Medical Journal, 373. View this article in WRRO
- Derivation and validation of a clinical severity score for acutely ill adults with suspected COVID-19: The PRIEST observational cohort study. PLoS ONE, 16(1). View this article in WRRO
- Early noninvasive cardiac testing after emergency department evaluation for suspected acute coronary syndrome. JAMA Internal Medicine, 180(12), 1621-1629. View this article in WRRO
- Delirium detection in older acute medical inpatients : a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method. BMC Medicine, 17(1). View this article in WRRO
- The Reality of Pain Scoring in the Emergency Department: Findings From a Multiple Case Study Design.. Annals of Emergency Medicine. View this article in WRRO
- Impact of the new medical examiner role on patient safety. BMJ, 363. View this article in WRRO
- Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis. Annals of internal medicine, 166(10), 715-724. View this article in WRRO
- Effectiveness of EDACS Versus ADAPT Accelerated Diagnostic Pathways for Chest Pain: A Pragmatic Randomized Controlled Trial Embedded Within Practice. Annals of Emergency Medicine, 68(1), 93-102.e1. View this article in WRRO
- Cost-effectiveness of Out-of-Hospital Continuous Positive Airway Pressure for Acute Respiratory Failure. Annals of Emergency Medicine, 65(5), 556-563.e6. View this article in WRRO
- A reanalysis of cluster randomized trials showed interrupted time-series studies were valuable in health system evaluation. Journal of Clinical Epidemiology, 68(3), 324-333.
- Comparison of conventional and high-sensitivity troponin in patients with chest pain: A collaborative meta-analysis. American Heart Journal, 169(1), 6-16.e6.
- A 2-hour diagnostic protocol for possible cardiac chest pain in the emergency department: a randomized clinical trial.. JAMA Intern Med, 174(1), 51-58.
- Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): A double-blind, randomised controlled trial. The Lancet Respiratory Medicine, 1(4), 293-300.
- Derivation and validation of a risk adjustment model for predicting seven day mortality in emergency medical admissions: mixed prospective and retrospective cohort study.. BMJ, 344, e2904. View this article in WRRO
- Noninvasive ventilation in acute cardiogenic pulmonary edema. NEW ENGL J MED, 359(2), 142-151.
- Effectiveness and safety of chest pain assessment to prevent emergency admissions: ESCAPE cluster randomised trial.. BMJ, 335(7621), 659. View this article in WRRO
- Meta-analysis: The value of clinical assessment in the diagnosis of deep venous thrombosis.. Ann Intern Med, 143(2), 129-139.
- Randomised controlled trial and economic evaluation of a chest pain observation unit compared with routine care.. BMJ, 328(7434), 254. View this article in WRRO
- Diagnosis and management of sepsis in the older adult. BMJ, e075585-e075585.
All publications
Journal articles
- Cost-Effectiveness of Early Non-Invasive Cardiac Testing for Suspected Acute Coronary Syndrome. ANNALS OF EMERGENCY MEDICINE, 84(4), S82-S82.
- Scoping review of the effectiveness of 10 high-impact initiatives (HIIs) for recovering urgent and emergency care services. BMJ Open Quality, 13(3), e002906-e002906.
- Acute aortic syndrome. BMJ, 386. View this article in WRRO
- Take-home naloxone administered in emergency settings: feasibility of intervention implementation in a cluster randomized trial. BMC Emergency Medicine, 24. View this article in WRRO
- Triage measurements in the emergency department overestimate blood pressure.. Emerg Med J.
- Diagnostic accuracy of alternative biomarkers for acute aortic syndrome: a systematic review.. Emerg Med J.
- Diagnostic Accuracy of D-Dimer for Acute Aortic Syndromes: Systematic Review and Meta-Analysis. Annals of Emergency Medicine.
- HTA51 Machine learning approaches to reduce economic impact of effective interventions. Value in Health, 27(6), S254-S254. View this article in WRRO
- Major Trauma Triage Tool Study (MATTS) expert consensus-derived injury assessment tool. British Paramedic Journal, 9(1), 10-22.
- Is a randomised controlled trial of take home naloxone distributed in emergency settings likely to be feasible and acceptable? Findings from a UK qualitative study exploring perspectives of people who use opioids and emergency services staff. BMC Emergency Medicine, 24(1). View this article in WRRO
- Service users' preferences and feasibility – which alternative care pathway for adult ambulance users achieves the optimal balance? Workshops for the COLLABORATE project. Seizure: European Journal of Epilepsy, 118, 17-27.
- Developing an alternative care pathway for emergency ambulance responses for adults with epilepsy: A Discrete Choice Experiment to understand which configuration service users prefer. Part of the COLLABORATE project. Seizure: European Journal of Epilepsy, 118, 28-37.
- Diagnostic strategies in postpartum individuals with suspected venous thromboembolism: A scoping review. Thrombosis Research, 236, 108-116.
- Prognostic accuracy of eight triage scores in suspected COVID-19 in an Emergency Department low-income setting: An observational cohort study. African Journal of Emergency Medicine, 14(1), 51-57.
- Effectiveness and cost effectiveness of pharmacological thromboprophylaxis for medical inpatients: decision analysis modelling study. BMJ Medicine, 3(1), e000408-e000408.
- Estimating the value of future research into thromboprophylaxis for women during pregnancy and after delivery: a value of information analysis. Journal of Thrombosis and Haemostasis.
- PB1532 How Can We Improve Recruitment to Trials for Prevention of Venous Thromboembolism during Pregnancy and the Puerperium? A Qualitative Evaluation of the Patients' Perspective. Research and Practice in Thrombosis and Haemostasis, 7, 101939-101939.
- PB1530 Diagnostic Strategies in Postpartum Individuals with Suspected Venous Thromboembolism: A Scoping Review. Research and Practice in Thrombosis and Haemostasis, 7, 101942-101942.
- Training and testing of a gradient boosted machine learning model to predict adverse outcome in patients presenting to emergency departments with suspected covid-19 infection in a middle-income setting. PLOS Digital Health, 2(9). View this article in WRRO
- Early computed tomography coronary angiography and preventative treatment in patients with suspected acute coronary syndrome: A secondary analysis of the RAPID-CTCA trial. American Heart Journal, 266, 138-148.
- Troponin in acute chest pain to risk stratify and guide effective use of computed tomography coronary angiography (TARGET-CTCA): a randomised controlled trial. Trials, 24.
- Building an understanding of Ethnic minority people’s Service Use Relating to Emergency care for injuries: the BE SURE study protocol. BMJ Open, 13(4).
- Decision-analysis modelling of effectiveness and cost-effectiveness of pharmacological thromboprophylaxis for surgical inpatients, using variable risk assessment models or other strategies. Journal of Thrombosis and Haemostasis.
- Multicentre open label randomised controlled trial of immediate enhanced ambulatory ECG monitoring versus standard monitoring in acute unexplained syncope patients: the ASPIRED study. BMJ Open, 13(2).
- Accuracy of efficient data methods to determine the incidence of hospital-acquired thrombosis and major bleeding in medical and surgical inpatients: a multicentre observational cohort study in four UK hospitals. BMJ Open, 13(2).
- 1522 The composite outcome fallacy in the PRIEST COVID-19 clinical prediction score. Emergency Medicine Journal, 39(12), A969.2-A969.
- Pre-hospital prediction of adverse outcomes in patients with suspected COVID-19 : development, application and comparison of machine learning and deep learning methods. Computers in Biology and Medicine. View this article in WRRO
- Clinical and cost-effectiveness of paramedic administered fascia iliaca compartment block for emergency hip fracture (RAPID 2)—protocol for an individually randomised parallel-group trial. Trials, 23(1).
- Early computed tomography coronary angiography in adults presenting with suspected acute coronary syndrome: the RAPID-CTCA RCT.. Health Technol Assess, 26(37), 1-114.
- PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO) : protocol for a multicentre, open-label, randomised controlled trial. BMJ Open, 12(6).
- New guidance on initial antimicrobial treatment of sepsis. British Medical Journal, 377.
- Presentation cardiac troponin and early computed tomography coronary angiography in patients with suspected acute coronary syndrome: a pre-specified secondary analysis of the RAPID-CTCA trial. European Heart Journal: Acute Cardiovascular Care. View this article in WRRO
- Research priorities for prehospital care of older patients with injuries: scoping review. Age and Ageing, 51(5).
- Accuracy of emergency medical service telephone triage of need for an ambulance response in suspected COVID-19: an observational cohort study.. BMJ Open, 12(5), e058628.
- Accuracy of telephone triage for predicting adverse outcomes in suspected COVID-19: an observational cohort study. BMJ Quality and Safety.
- Composite outcomes in clinical prediction modeling: are we trying to predict apples and oranges?. Annals of Emergency Medicine. View this article in WRRO
- 965 Accuracy of emergency (999) telephone triage for predicting adverse outcomes in suspected COVID-19: an observational cohort study. Emergency Medicine Journal, 39(3), 250.1-25250.
- 798 Accuracy of telephone triage for predicting adverse outcomes in suspected COVID-19: an observational cohort study. Emergency Medicine Journal, 39(3), 256-256.
- Prognostic accuracy of triage tools for adults with suspected COVID-19 in a prehospital setting : an observational cohort study. Emergency Medicine Journal.
- Does hospital admission/observation for chest pain improve patient outcomes after emergency department evaluation for suspected acute coronary syndrome?. Journal of General Internal Medicine, 37(4), 745-752. View this article in WRRO
- Abstract 10157: Incremental medical expenditure and effectiveness of early non-invasive cardiac testing in suspected acute coronary syndrome. Circulation, 144(Suppl 1). View this article in WRRO
- Should prehospital early warning scores be used to identify which patients need urgent treatment for sepsis?. BMJ, 2021(375).
- Early computed tomography coronary angiography in patients with suspected acute coronary syndrome: randomised controlled trial. BMJ: British Medical Journal, 374. View this article in WRRO
- PP25 The take home naloxone intervention multicentre emergency setting feasibility (TIME) trial: an early perspective from one UK ambulance service. Emergency Medicine Journal, 38(9), A11.1-A11.
- Comparison of qSOFA and Hospital Early Warning Scores for prognosis in suspected sepsis in emergency department patients : a systematic review. Emergency Medicine Journal.
- Retrospective single-centre descriptive study of the characteristics, management and outcomes of adult patients with suspected sepsis in the emergency department. Emergency Medicine Journal.
- Do not attempt cardiopulmonary resuscitation (DNACPR) decisions in people admitted with suspected COVID-19 : secondary analysis of the PRIEST observational cohort study. Resuscitation, 164, 130-138. View this article in WRRO
- Risk assessment models for venous thromboembolism in hospitalised adult patients: a systematic review. BMJ Open, 11(7). View this article in WRRO
- Realising the full potential of data-enabled trials in the UK : a call for action. BMJ Open, 11(6).
- Prognostic accuracy of emergency department triage tools for adults with suspected COVID-19: the PRIEST observational cohort study.. Emerg Med J.
- Which is the best model to assess risk for venous thromboembolism in hospitalised patients?. BMJ: British Medical Journal, 373. View this article in WRRO
- Emergency Medicine Journal COVID-19 monthly top five. Emergency Medicine Journal, 38(3), 240-242. View this article in WRRO
- A qualitative exploration of value and waste in a Trinidadian emergency department patient flow process : perspectives of patients and clinicians. Journal of Health Organization and Management.
- Qualitative exploration of the Medical Examiner role in identifying problems with the quality of patient care.. BMJ open, 11(2), e048007.
- Cost-effectiveness of out-of-hospital continuous positive airway pressure for acute respiratory failure: decision analytic modelling using data from a feasibility trial.. BMC Emerg Med, 21(1), 13.
- Derivation and validation of a clinical severity score for acutely ill adults with suspected COVID-19: The PRIEST observational cohort study. PLoS ONE, 16(1). View this article in WRRO
- Post-exertion oxygen saturation as a prognostic factor for adverse outcome in patients attending the emergency department with suspected COVID-19: a substudy of the PRIEST observational cohort study. Emergency Medicine Journal.
- Early noninvasive cardiac testing after emergency department evaluation for suspected acute coronary syndrome. JAMA Internal Medicine, 180(12), 1621-1629. View this article in WRRO
- 356 Comparison of qSOFA, and hospital early warning scores for prognosis in suspected sepsis in emergency department patients: a systematic review. Emergency Medicine Journal, 37(12), 843-843.
- The diagnostic accuracy of pre-hospital assessment of acute respiratory failure. British Paramedic Journal, 5(3), 15-22. View this article in WRRO
- Qualitative exploration of patient flow in a Caribbean emergency department. BMJ Open, 10(12).
- Characterisation of 22445 patients attending UK emergency departments with suspected COVID-19 infection : observational cohort study. PLoS ONE, 15(11).
- Controlled observational study and economic evaluation of the effect of city-centre night-time alcohol intoxication management services on the emergency care system compared with usual care. Emergency Medicine Journal.
- Diagnostic accuracy of the magnetocardiograph for patients with suspected acute coronary syndrome. Emergency Medicine Journal. View this article in WRRO
- PP32 Major trauma triage tools study (MATTS) expert consensus meetings. Emergency Medicine Journal, 37(10), e14.3-e16.
- Seizure first aid training for people with epilepsy attending emergency departments and their significant others: the SAFE intervention and feasibility RCT. Health Services and Delivery Research, 8(39). View this article in WRRO
- Harnessing inter-disciplinary collaboration to improve emergency care in low- and middle-income countries (LMICs): results of research prioritisation setting exercise. BMC Emergency Medicine, 20(1).
- Protocol for Take-home naloxone In Multicentre Emergency (TIME) settings: feasibility study. Pilot and Feasibility Studies, 6(1). View this article in WRRO
- Is a definitive trial of prehospital continuous positive airway pressure versus standard oxygen therapy for acute respiratory failure indicated? The ACUTE pilot randomised controlled trial. BMJ Open, 10(7). View this article in WRRO
- Evaluating alcohol intoxication management services: the EDARA mixed-methods study. Health Services and Delivery Research, 8(24). View this article in WRRO
- Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT) : an international randomised, double-blind, placebo-controlled trial. Lancet, 395(10241), 1927-1936. View this article in WRRO
- The UK hibernated pandemic influenza research portfolio : triggered for COVID-19. The Lancet Infectious Diseases. View this article in WRRO
- Seizure first aid training for people with Epilepsy (SAFE) frequently attending emergency departments and their significant others : results of a UK multi-centre randomised controlled pilot trial. BMJ Open, 10(4). View this article in WRRO
- Accuracy of PE rule-out strategies in pregnancy : secondary analysis of the DiPEP study prospective cohort. Emergency Medicine Journal. View this article in WRRO
- Clinically unnecessary and avoidable emergency health service use for epilepsy: A survey of what English services are doing to reduce it.. Seziure, 76, 156-160. View this article in WRRO
- Implementation of rapid rule out of myocardial infarction using high-sensitivity troponin : cross-sectional survey of English hospitals. Emergency Medicine Journal. View this article in WRRO
- Reply to Thromboprophylaxis in temporary lower limb immobilization : extrapolate with care. Journal of Thrombosis and Haemostasis, 18(2), 519-520. View this article in WRRO
- Pharmacological thromboprophylaxis to prevent venous thromboembolism in patients with temporary lower limb immobilization after injury : systematic review and network meta‐analysis. Journal of Thrombosis and Haemostasis, 18(2), 422-438. View this article in WRRO
- How can pain management in the emergency department be improved? Findings from multiple case study analysis of pain management in three UK emergency departments. Emergency Medicine Journal. View this article in WRRO
- Different strategies for pharmacological thromboprophylaxis for lower-limb immobilisation after injury: systematic review and economic evaluation. Health Technology Assessment, 23(63), 1-190. View this article in WRRO
- The DiPEP study : an observational study of the diagnostic accuracy of clinical assessment, D-dimer and chest x-ray for suspected pulmonary embolism in pregnancy and postpartum. Obstetric Anesthesia Digest, 39(4), 215-216. View this article in WRRO
- Progression criteria in trials with an internal pilot : an audit of publicly funded randomised controlled trials. Trials, 20(1). View this article in WRRO
- Delirium detection in older acute medical inpatients : a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method. BMC Medicine, 17(1). View this article in WRRO
- The acceptability of alcohol intoxication management services to users : a mixed methods study. Drug and Alcohol Review. View this article in WRRO
- Thromboprophylaxis in lower limb immobilisation after injury (TiLLI). Emergency Medicine Journal, 0, 1-6. View this article in WRRO
- Developing patient-centred, feasible alternative care for adult emergency department users with epilepsy : protocol for the mixed-methods observational ‘collaborate’ project. BMJ Open, 9(11). View this article in WRRO
- The Reality of Pain Scoring in the Emergency Department: Findings From a Multiple Case Study Design.. Annals of Emergency Medicine. View this article in WRRO
- PP9 Managing alcohol intoxication in the night-time economy : staff and patient perspectives. Emergency Medicine Journal, 36(10). View this article in WRRO
- The 4 ‘A’s test for detecting delirium in acute medical patients : a diagnostic accuracy study. Health Technology Assessment, 23(40), 1-193. View this article in WRRO
- The UK’s pandemic influenza research portfolio: a model for future research on emerging infections. The Lancet Infectious Diseases, 19(8), e295-e300. View this article in WRRO
- Diagnosis of Pulmonary Embolism During Pregnancy. Annals of Internal Medicine, 171(2), 146-147. View this article in WRRO
- Decision‐analysis modelling of the effects of thromboprophylaxis for people with lower limb immobilisation for injury. British Journal of Haematology, 186(1), 166-168. View this article in WRRO
- Diagnosis of Suspected Pulmonary Embolism in Pregnancy. New England Journal of Medicine, 380(25), e49-e49.
- Developing new ways of measuring the quality and impact of ambulance service care: the PhOEBE mixed-methods research programme. Programme Grants for Applied Research, 7(3). View this article in WRRO
- Individual risk factors predictive of venous thromboembolism in patients with temporary lower limb immobilisation due to injury: a systematic review.. Journal of Thrombosis and Haemostasis, 17(2), 329-344. View this article in WRRO
- The DiPEP study: an observational study of the diagnostic accuracy of clinical assessment, D-dimer and chest x-ray for suspected pulmonary embolism in pregnancy and postpartum. BJOG: An International Journal of Obstetrics & Gynaecology, 126(3), 383-392. View this article in WRRO
- Impact of the new medical examiner role on patient safety. BMJ, 363. View this article in WRRO
- Development and prospective external validation of a tool to predict poor recovery at 9 months after acute ankle sprain in UK emergency departments: the SPRAINED prognostic model. BMJ Open, 8(11). View this article in WRRO
- Prognostic models for identifying risk of poor outcome in people with acute ankle sprains: the SPRAINED development and external validation study. Health Technology Assessment, 22(64). View this article in WRRO
- Do all HEART Scores beat the same: evaluating the interoperator reliability of the HEART Score.. Emergency Medicine Journal. View this article in WRRO
- Selecting pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging: the DiPEP diagnostic study with decision-analysis modelling.. Health Technology Assessment, 22(47). View this article in WRRO
- Interventions to improve patient flow in emergency departments: an umbrella review.. Emergency Medicine Journal. View this article in WRRO
- The ACUTE (Ambulance CPAP: Use, Treatment effect and economics) feasibility study: a pilot randomised controlled trial of prehospital CPAP for acute respiratory failure. Pilot and Feasibility Studies, 4(1). View this article in WRRO
- The DiPEP (Diagnosis of PE in Pregnancy) biomarker study: An observational cohort study augmented with additional cases to determine the diagnostic utility of biomarkers for suspected venous thromboembolism during pregnancy and puerperium. British Journal of Haematology, 180(5), 694-704. View this article in WRRO
- Managing alcohol-related attendances in emergency care: can diversion to bespoke services lessen the burden?. Emergency Medicine Journal, 35(2), 79-82. View this article in WRRO
- Protocol for validation of the 4AT, a rapid screening tool for delirium: a multicentre prospective diagnostic test accuracy study. BMJ Open, 8(2), e015572-e015572. View this article in WRRO
- Bypassing nearest hospital for more distant neuroscience care in head-injured adults with suspected traumatic brain injury: findings of the head injury transportation straight to neurosurgery (HITS-NS) pilot cluster randomised trial.. BMJ Open, 7(10). View this article in WRRO
- Consensus-derived clinical decision rules to guide advanced imaging decisions for pulmonary embolism in pregnancy and the postpartum period. European Journal of Emergency Medicine. View this article in WRRO
- Rapid Rule-out of Acute Myocardial Infarction With a Single High-Sensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis. Annals of internal medicine, 166(10), 715-724. View this article in WRRO
- Developing and assessing the acceptability of an epilepsy first aid training intervention for patients who visit UK emergency departments: A multi-method study of patients and professionals. Epilepsy and Behavior, 68, 177-185. View this article in WRRO
- Informing efficient randomised controlled trials: Exploration of challenges in developing progression criteria for internal pilot studies. BMJ Open, 7(e013537). View this article in WRRO
- AHEAD Study: an observational study of the management of anticoagulated patients who suffer head injury. BMJ Open, 7(1). View this article in WRRO
- The acceptability and feasibility of an anxiety reduction intervention for emergency department patients with non-cardiac chest pain. Psychology, Health & Medicine, 22(1), 1-11. View this article in WRRO
- Paramedics' views on their seizure management learning needs: a qualitative study in England.. BMJ Open, 7(1), e014024-e014024. View this article in WRRO
- Should all anticoagulated patients with head injury receive a CT scan? Decision-analysis modelling of an observational cohort. BMJ Open. View this article in WRRO
- The RAPID-CTCA trial (Rapid Assessment of Potential Ischaemic Heart Disease with CTCA) - a multicentre parallel-group randomised trial to compare early computerised tomography coronary angiography versus standard care in patients presenting with suspected or confirmed acute coronary syndrome: study protocol for a randomised controlled trial.. Trials, 17(1), 579-579. View this article in WRRO
- Qualitative study of paramedics' experiences of managing seizures: a national perspective from England. BMJ Open, 6(11). View this article in WRRO
- Can emergency medicine research benefit from adaptive design clinical trials?. Emergency Medicine Journal, 34, 243-248. View this article in WRRO
- Patient and public involvement in emergency care research. Emergency Medicine Journal, 33, 665-670. View this article in WRRO
- High-sensitivity cardiac troponin at 3 hours: is the cat among the pigeons?. Heart, 102, 1253-1254. View this article in WRRO
- Effectiveness of EDACS Versus ADAPT Accelerated Diagnostic Pathways for Chest Pain: A Pragmatic Randomized Controlled Trial Embedded Within Practice. Annals of Emergency Medicine, 68(1), 93-102.e1. View this article in WRRO
- How do patients feel about taking part in clinical trials in emergency care?. Emergency Medicine Journal, 33(6), 376-380. View this article in WRRO
- Patient expectations of emergency hospital admission. European Journal of Emergency Medicine, 23(3), 203-207.
- The Recognition of STEMI by Paramedics and the Effect of Computer inTerpretation (RESPECT): a randomised crossover feasibility study. Emergency Medicine Journal, 33(7), 471-476. View this article in WRRO
- The problem of pulmonary embolism diagnosis in pregnancy. British Journal of Haematology, n/a-n/a. View this article in WRRO
- Lowering bed occupancy: A life-saving intervention?. Emergency Medicine Journal, 33(2), 84-84. View this article in WRRO
- Variation in avoidable emergency admissions: multiple case studies of emergency and urgent care systems. Journal of Health Services Research & Policy, 21(1), 5-14. View this article in WRRO
- Development and validation of a score to identify in the Emergency Department patients who may benefit from a time-critical intervention: a cohort study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 23(1). View this article in WRRO
- Highlights from this issue. Emergency Medicine Journal, 32(9), 669-669.
- THE RECOGNITION OF STEMI BY PARAMEDICS AND THE EFFECT OF COMPUTER INTERPRETATION (RESPECT): A CLUSTER-RANDOMISED CROSSOVER PILOT STUDY. Emergency Medicine Journal, 32(5), 421.1-421. View this article in WRRO
- Cost-effectiveness of Out-of-Hospital Continuous Positive Airway Pressure for Acute Respiratory Failure. Annals of Emergency Medicine, 65(5), 556-563.e6. View this article in WRRO
- Uncontrolled before-after studies: discouraged by Cochrane and theEMJ. Emergency Medicine Journal, 32(7), 507-508. View this article in WRRO
- Highlights from this issue. Emergency Medicine Journal, 32(3), 173-173.
- A reanalysis of cluster randomized trials showed interrupted time-series studies were valuable in health system evaluation. Journal of Clinical Epidemiology, 68(3), 324-333.
- ‘Seizure First Aid Training’ for people with epilepsy who attend emergency departments, and their family and friends: study protocol for intervention development and a pilot randomised controlled trial. BMJ Open, 5(7), e009040-e009040. View this article in WRRO
- Comparison of conventional and high-sensitivity troponin in patients with chest pain: A collaborative meta-analysis. American Heart Journal, 169(1), 6-16.e6.
- The PAndemic INfluenza Triage in the Emergency Department (PAINTED) pilot study. Health Technology Assessment, 19(3). View this article in WRRO
- The clinical and diagnostic performance characteristics of the high sensitivity Abbott cardiac troponin I assay. Clinical Biochemistry, 48(4-5), 275-281.
- The economics of cardiac biomarker testing in suspected myocardial infarction. Clinical Biochemistry, 48(4-5), 213-217.
- When should we use diagnostic imaging to investigate for pulmonary embolism in pregnant and postpartum women?. Emerg Med J, 32(1), 78-82.
- What do hospital mortality rates tell us about quality of care?. Emerg Med J, 32(3), 244-247.
- Factors influencing unspecified chest pain admission rates in England. Emergency Medicine Journal. View this article in WRRO
- Disaster management in low- and middle-income countries: Scoping review of the evidence base. Emergency Medicine Journal. View this article in WRRO
- Interventions to improve the management of pain in emergency departments: systematic review and narrative synthesis.. Emerg Med J, 31(e1), e9-e18. View this article in WRRO
- Prediction of unsuccessful treatment in patients with severe acute asthma.. Emerg Med J, 31(e1), e40-e45.
- Prehospital Noninvasive Ventilation for Acute Respiratory Failure: Systematic Review, Network Meta-analysis, and Individual Patient Data Meta-analysis. Academic Emergency Medicine, 21(9), 960-970. View this article in WRRO
- Illness representations, psychological distress and non-cardiac chest pain in patients attending an emergency department.. Psychol Health, 29(11), 1265-1282. View this article in WRRO
- Highlights from the issue. Emergency Medicine Journal, 31(3), 175-175.
- Trial registration: must take place before or at the onset of enrolment.. Emerg Med J, 31(3), 176.
- Highlights from this issue. Emergency Medicine Journal, 31(9), 695-695.
- A 2-hour diagnostic protocol for possible cardiac chest pain in the emergency department: a randomized clinical trial.. JAMA Intern Med, 174(1), 51-58.
- A system-wide approach to explaining variation in potentially avoidable emergency admissions: national ecological study.. BMJ Qual Saf, 23(1), 47-55. View this article in WRRO
- Comparison of contemporary troponin assays with the novel biomarkers, heart fatty acid binding protein and copeptin, for the early confirmation or exclusion of myocardial infarction in patients presenting to the emergency department with chest pain.. Heart, 100(2), 140-145.
- Evaluation of the DAVROS (Development And Validation of Risk-adjusted Outcomes for Systems of emergency care) risk-adjustment model as a quality indicator for healthcare.. Emerg Med J, 31(6), 471-475. View this article in WRRO
- Patient expectations of minor injury care: a cross-sectional survey.. Emerg Med J, 31(7), 567-570.
- Paramedic perceptions of the feasibility and practicalities of prehospital clinical trials: a questionnaire survey.. Emerg Med J, 31(6), 499-504.
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Conference proceedings papers
- 2615 Decision-analytic modelling of strategies for investigating suspected acute aortic syndrome. RCEM Annual Scientific Conference 2024 Abstracts (pp A12.2-A12)
- 2613 Diagnostic accuracy of the aortic dissection detection risk score alone or with D-dimer for acute aortic syndromes: systematic review and meta-analysis. RCEM Annual Scientific Conference 2024 Abstracts (pp A9.1-A9)
- 2553 Diagnostic accuracy of alternative biomarkers for acute aortic syndrome: a systematic review. RCEM Annual Scientific Conference 2024 Abstracts (pp A17.1-A17)
- 2245 Mixed methods study exploring factors influencing ambulance clinician decisions to pre-alert emergency departments (EDs) of a patient’s arrival. RCEM Annual Scientific Conference Glasgow 2023 Meeting Abstracts
- 2109 Prehospital early warning scores for adults with suspected sepsis: retrospective diagnostic cohort study. RCEM Annual Scientific Conference Glasgow 2023 Meeting Abstracts
- PP66 Ethnic differences in injury mortality rates among adult emergency healthcare service users in developed countries – a scoping review. 999 EMS Research Forum 2023 meeting abstracts
- PP33 Which patients receive a prealert? Analysis of linked data in three ambulance services. 999 EMS Research Forum 2023 meeting abstracts
- PP32 What factors affect pre-hospital pre-alerts? Analysis of routine ambulance data. 999 EMS Research Forum 2023 meeting abstracts
- 1482 Prognostic accuracy of triage tools for adults with suspected COVID-19 in a middle-income setting. Emergency Medicine Journal, Vol. 39(12) (pp A976-A977)
- PP26 Exploring the use of pre-hospital pre-alerts and their impact on patients, ambulance service and emergency department staff: protocol for a mixed methods study. Emergency Medicine Journal, Vol. 39(9) (pp e5.19-e5.19)
- Rapid Assessment of Potential Ischaemic Heart Disease With Ctca: The Rapid-ctca Trial. A Randomised Trial of Ctcain the Evaluation, Intervention and Outcome Ofadults With Suspected or Confirmed Acute Coronary Syndrome Presenting to the Emergency Department. CIRCULATION, Vol. 142(24) (pp E471-E472)
- Pre-hospital CPAP for acute respiratory failure : the ACUTE feasibility and pilot randomised controlled trial. British Paramedic Journal, Vol. 4(3) (pp 53-54). Cardiff, Wales, 24 September 2019 - 24 September 2019. View this article in WRRO
- PP25 ‘I wish there was CPAP in every box’ : internet-based survey responses of clinicians recruiting to a pilot randomised controlled trial of continuous positive airway pressure (CPAP) for patients with acute respiratory failure. Emergency Medicine Journal, Vol. 36(10) View this article in WRRO
- PP22 Box randomisation - a novel method for allocation in pre-hospital randomised controlled trials : the ACUTE study experience. Emergency Medicine Journal, Vol. 36(10) View this article in WRRO
- PP28 ‘They are not silly people – they know the difference’ : clinician focus group views on a pilot randomised controlled trial of prehospital continuous positive airway pressure (CPAP). Emergency Medicine Journal, Vol. 36(10) View this article in WRRO
- 22 Public and patient involvement in prehospital care research development – designing the rapid 2 trial. Abstracts
- View this article in WRRO Seizure First Aid Training for People with Epilepsy who Attend Emergency Departments and Their Family and Friends: Results from a Pilot Randomised Controlled Trial. EPILEPSIA, Vol. 59 (pp S140-S140)
- 10 Decision analysis modelling of diagnostic strategies for suspected pulmonary embolism in pregnancy: the DiPEP economic evaluation. Emergency Medicine Journal, Vol. 34(12) (pp A867-A868)
- 28 Are we measuring what we think we are measuring? Qualitative research exploring the role of the 0–10 pain score within the adult emergency department. Emergency Medicine Journal, Vol. 34(12) (pp A879.1-A879)
- 235 Whose Pain is it Anyway? Qualitative Research Exploring How the 0-10 Pain Score is Used in Practice Within the Adult Emergency Department. Annals of Emergency Medicine, Vol. 70(4) (pp S93-S94)
- Evaluation of the European Society of Cardiology recommended rapid diagnostic algorithms in a challenging low risk cohort. EUROPEAN HEART JOURNAL, Vol. 38 (pp 998-998)
- PROGNOSTIC SIGNIFICANCE OF AN ELEVATED CONVENTIONAL OR HIGH-SENSITIVITY CARDIAC TROPONIN IN PATIENTS WITH CHEST PAIN WITH AND WITHOUT A DIAGNOSIS OF MYOCARDIAL INFARCTION. Journal of the American College of Cardiology, Vol. 65(10) (pp A127-A127)
- Absolute or relative deltas for diagnosis of myocardial infarction and how should they be calculated. EUROPEAN HEART JOURNAL, Vol. 35 (pp 140-140)
- PRE-HOSPITAL CONTINUOUS POSITIVE AIREWAY PRESSURE (CPAP) FOR ACUTE RESPIRATORY FAILURE: AN ECONOMIC ANALYSIS. Emergency Medicine Journal, Vol. 31(9) (pp 780.2-781)
- ADHERENCE TO THE NICE HEAD INJURY GUIDELINES 2007 AND 2014 IN ANTICOAGULATED PATIENTS. Emergency Medicine Journal, Vol. 31(9) (pp 775.2-775)
- THE AHEAD STUDY: MANAGING ANTICOAGULATED PATIENTS WHO SUFFER HEAD INJURY. Emergency Medicine Journal, Vol. 31(9) (pp 775.1-775)
- Prediction of unsuccessful treatment in patients with severe acute asthma: an analysis from the 3mg trial.. Emerg Med J, Vol. 30(10) (pp 872-873). England
- The 3mg trial: a randomised controlled trial of intravenous or nebulised magnesium sulphate versus placebo in adults with severe acute asthma.. Emerg Med J, Vol. 30(10) (pp 866). England
- The Head Injury Transportation Straight To Neurosurgery (HITS-NS) Trial: Introduction To The Study, Challenges Of The Set-Up Phase And Progress. JOURNAL OF NEUROSURGERY, Vol. 119(2) (pp A552-A552)
- The incidence of troponin elevation in non AMI patients in the unselected emergency room population. EUROPEAN HEART JOURNAL, Vol. 34 (pp 73-73)
- COST-EFFECTIVENESS OF PRESENTATION AND DELAYED TROPONIN TESTING FOR ACUTE MYOCARDIAL INFARCTION. VALUE IN HEALTH, Vol. 15(7) (pp A633-A633)
- DIAGNOSTIC ACCURACY OF EARLY BIOMARKERS FOR ACUTE CORONARY SYNDROME (ACS). VALUE IN HEALTH, Vol. 15(7) (pp A361-A361)
- To examine the diagnostic accuracy of highly sensitive troponin assays using diagnosis based on the universal definition of myocardial infarction in the unselected emergency room population. EUROPEAN HEART JOURNAL, Vol. 33 (pp 622-622)
- The diagnostic accuracy of novel biomarkers of myocardial injury in the unselected emergency room population. EUROPEAN HEART JOURNAL, Vol. 33 (pp 911-911)
- Economic analysis of the randomised assessment of treatment using panel assay of cardiac markers - contemporary biomarker evaluation study (RATPAC CBE). EUROPEAN HEART JOURNAL, Vol. 33 (pp 897-897)
- PMD40 Cost-Effectiveness of Presentation and Delayed Troponin Testing for Acute Myocardial Infarction. Value in Health, Vol. 15(4) (pp A69-A69)
- Diagnostic modelling of suspected acute coronary syndrome. 2012 Operational Research Society Simulation Workshop, SW 2012 (pp 25-35)
- Can Illness representations predict psychological morbidity in non-cardiac chest pain patients attending an emergency department?. PSYCHOLOGY & HEALTH, Vol. 27 (pp 139-139)
- The Head Injury Transportation Straight to Neurosurgery (HITS-NS) Trial: An Introduction to the Study and the Challenges of the Set-Up Phase. BRAIN INJURY, Vol. 26(4-5) (pp 534-535)
- CLINICAL DECISION RULES FOR ADULTS WITH MINOR HEAD INJURY: A SYSTEMATIC REVIEW. VALUE IN HEALTH, Vol. 14(7) (pp A244-A244)
- DIAGNOSTIC ACCURACY OF CLINICAL CHARACTERISTICS FOLLOWING MINOR HEAD INJURY: A SYSTEMATIC REVIEW AND META-ANALYSIS. VALUE IN HEALTH, Vol. 14(7) (pp A245-A245)
- BIOCHEMICAL MARKERS FOR THE IDENTIFICATION OF INTRACRANIAL INJURY FOLLOWING MINOR HEAD INJURY: A SYSTEMATIC REVIEW AND META-ANALYSIS. VALUE IN HEALTH, Vol. 14(7) (pp A244-A244)
- The RATPAC Trial (Randomised Assessment of Treatment using Panel Assay of Cardiac markers): a randomised controlled trial of point-of-care cardiac markers in the emergency department. EUROPEAN HEART JOURNAL, Vol. 31 (pp 947-947)
- IT IN THE EMERGENCY DEPARTMENT What is the Impact of Technology?. HEALTHINF 2009: PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON HEALTH INFORMATICS (pp 454-457)
- Non-invasive ventilation in patients with acute cardiogenic pulmonary oedema: The 3CPO trial (a multicentre randomised controlled trial). THORAX, Vol. 62 (pp A8-A8)
Reports
- The RATPAC (Randomised Assessment of Treatment using Panel Assay of Cardiac markers) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. View this article in WRRO
- The ESCAPE multi-centre evaluation of the role of chest pain units in the NHS
- A Review of the costs and benefits of Helicopter Emergency Ambulance Services in England and Wales
Posters
- PP15 Research priorities for prehospital care of older patients with injuries: scoping review.
- PRE-HOSPITAL NON-INVASIVE VENTILATION FOR ACUTE RESPIRATORY FAILURE: A SYSTEMATIC REVIEW AND NETWORK META ANALYSIS.
- Clinical Decision Rules for children with minor head injury: A systematic review. European Society of Emergency Medicine,(EuSEM) Stockholm.
- A systematic review of Clinical Decision Rules in the management of adult minor head injury.
- Diagnostic accuracy of individual characteristics following minor head injury in children: A systematic review.
- Management of isolated minor head injury in the United Kingdom.
- Diagnostic accuracy of early biomarkers for acute coronary syndrome (ACS) (2012).
- Diagnostic accuracy of clinical characteristics following minor head injury: a systematic review and meta-analysis.
- Diagnostic accuracy of clinical characteristics following minor head injury: a systematic review and meta-analysis.
- Prognostic accuracy of Exercise ECG and CT Coronary Angiography to predict Major Adverse Cardiac Events (MACE) in patients with suspected Acute Coronary Syndrome (ACS): A systematic review (2012).
- The role of biochemical markers in the identification of intracranial pathology following minor head injury: a systematic review and meta-analysis.
- Clinical decision rules for adults with minor head injury: a systematic review.
- Clinical Decision Rules for children with minor head injury: A systematic review.
- Pre-hospital non-invasive ventilation for acute respiratory failure: a systematic review and network meta-analysis. 999 EMS Research Forum Conference.
Other
- Diagnosis of Suspected Pulmonary Embolism in Pregnancy. Reply.. N Engl J Med, 380(25), e49.
- The importance of journey times to hospital in urban areas - Response. EMERG MED J, 25(9), 618-618.
- Reply. Emergency Medicine Journal, 25(9), 618.
- Response to performance of the Hull Salford Cambridge Decision Rule: the start of the traumatic brain injury (TBI) assessment and recovery journey. Emergency Medicine Journal.
Preprints
- Acceptability and utility of an online patient-completed clinical decision aid for the differential diagnosis of transient loss of consciousness: a qualitative interview study (Preprint), JMIR Publications Inc..
- Accuracy of the National Early Warning Score version 2 (NEWS2) in predicting need for time-critical treatment: Retrospective observational cohort study, Cold Spring Harbor Laboratory.
- What factors predict ambulance pre-alerts to the emergency department? Analysis of routine data from three UK ambulance services., Research Square Platform LLC.
- Is a definitive trial of Take-Home Naloxone in emergency settings indicated? Results of a cluster randomised feasibility study, Research Square Platform LLC.
- What influences women’s decisions to participate in trials for prevention of venous thromboembolism during pregnancy and the puerperium: a qualitative study, Research Square Platform LLC.
- How do Emergency Departments respond to ambulance pre-alert calls? A qualitative exploration of the management of pre-alert in six UK Emergency Departments, Cold Spring Harbor Laboratory.
- Variation in ambulance pre-alert process and practice: Cross-sectional survey of ambulance clinicians, Cold Spring Harbor Laboratory.
- What factors predict ambulance pre-alerts to the emergency department? Analysis of routine data from 3 UK ambulance services, Cold Spring Harbor Laboratory.
- Is a randomised controlled trial of take home naloxone distributed in emergency settings likely to be feasible and acceptable? Findings from a UK qualitative study exploring perspectives of people who use opioids and emergency services staff, Research Square Platform LLC.
- LMIC-PRIEST: Derivation and validation of a clinical severity score for acutely ill adults with suspected COVID-19 in a middle-income setting, Cold Spring Harbor Laboratory.
- Prognostic accuracy of triage tools for adults with suspected COVID-19 in a middle-income setting: an observational cohort study, Cold Spring Harbor Laboratory.
- Pre-Hospital Prediction of Adverse Outcomes in Patients with Suspected COVID-19: Development, Application and Comparison of Machine Learning and Deep Learning Methods.
- Accuracy of emergency medical service telephone triage of need for an ambulance response in suspected COVID-19: An observational cohort study.
- Accuracy of telephone triage for predicting adverse outcome in suspected COVID-19: An observational cohort study, Cold Spring Harbor Laboratory.
- An Economic Evaluation of Triage Tools For Patients With Suspected Severe Injuries In England, Research Square Platform LLC.
- Cost-effectiveness of Out-of-Hospital Continuous Positive Airway Pressure for Acute Respiratory Failure: Decision analytic modelling using data from a feasibility trial, Research Square Platform LLC.
- Cost-effectiveness of Out-of-Hospital Continuous Positive Airway Pressure for Acute Respiratory Failure: Decision analytic modelling using data from a feasibility trial, Research Square Platform LLC.
- Derivation and validation of a clinical severity score for acutely ill adults with suspected COVID-19: The PRIEST observational cohort study, Cold Spring Harbor Laboratory.
- Prognostic accuracy of emergency department triage tools for adults with suspected COVID-19: The PRIEST observational cohort study, Cold Spring Harbor Laboratory.
- Prognostic accuracy of emergency department triage tools for children with suspected COVID-19: The PRIEST observational cohort study, Cold Spring Harbor Laboratory.
- Harnessing Inter-disciplinary Collaboration to Improve Emergency Care in Low- and Middle-income Countries (LMICS): Results of Research Prioritisation Setting Exercise, Research Square Platform LLC.
- Protocol for Take home naloxone In Multicentre Emergency setting (TIME): Feasibility Study, Research Square Platform LLC.
- Protocol for Take home naloxone In Multicentre Emergency setting (TIME): Feasibility Study, Research Square Platform LLC.
- Randomised Controlled Trial of Early CT Coronary Angiography in Patients With Suspected Acute Coronary Syndrome.
- Teaching interests
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My teaching interests are critical appraisal of the scientific literature, promoting evidence-based health care, advanced trauma life support (ATLS) and diagnostic pathways in emergency medicine.
I am interested in supervising students undertaking research in emergency care, such as evaluation of health technologies, changes to service delivery, methods to improve decision-making and methods for evaluating the quality of emergency care.