Saleema Selwiyn Rex

Population Health, School of Medicine and Population Health

PGR student

ssrex1@sheffield.ac.uk
07904206248

+44 114 273 0870 (Fax)

Room 3.04, -none-

Profile

I am a PhD student, evaluating statistical methods that can be used to obtain treatment effect estimates from complex causal mechanisms using cancer registry data by emulating target trial(s). This PhD is jointly funded by Yorkshire Cancer Research (YCR) and BresMed Health Solutions Ltd. My supervisors are Dr Nick Latimer, Prof Ron Akehurst and Mr Mike Bradburn.

I worked as a Statistician/Research Associate in the Clinical Trials Research Unit (CTRU), University of Sheffield and as a Research Fellow - Statistician in York Trials Unit after completing an MSc in Medical Statistics from the London School of Hygiene and Tropical Medicine in Oct 2018. Prior to that, I worked in Sheffield CTRU as a Data Specialist for three years and preceding that as Data Management Officer for three years. I also have experience working as a Data Analyst Programmer for five years. In addition to my master’s degree, my qualifications include a Graduate Certificate in Statistics, P.G. Diploma in Computing, and a B.A. in Communicative English.

Qualifications

MSc in Medical Statistics, London School of Hygiene and Tropical Medicine (LSHTM), London. Oct 2018.

Graduate Certificate in Statistics, The University of Sheffield, UK. Jun 2014

PG Diploma in Computing for Commerce and Industry, The Open university, UK. Jul 2008

BA Communicative English, Mahatma Gandhi University, Kerala, India. Jun 1998

Research interests

PhD title: Evaluating the use of causal inference methods for the analysis of cancer registry data.

I have an interest in causal inference and the use of routine data in clinical research.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Horner D, Rex S, Reynard C, Bursnall M, Bradburn M, de Wit K, Goodacre S & Hunt BJ (2023) Accuracy of efficient data methods to determine the incidence of hospital-acquired thrombosis and major bleeding in medical and surgical inpatients: a multicentre observational cohort study in four UK hospitals. BMJ Open, 13(2).
Thornhill M, Crum A, Rex S, Campbell R, Stone T, Bradburn M, Fibisan V, Dayer M, Prendergast B, Lockhart P , Baddour P et al (2022) Infective endocarditis following invasive dental procedures: IDEA case-crossover study. Health Technology Assessment, 26(28).
Thornhill M, Crum A, Rex S, Stone T, Campbell R, Bradburn M, Fibisan V, Lockhart P, Springer B, Baddour L & Nicholl J (2022) Analysis of prosthetic joint infections following invasive dental procedures in England. JAMA Network Open, 5(1). View this article in WRRO
Rex SS, Kottam L, McDaid C, Brealey S, Dias J, Hewitt CE, Keding A, Lamb SE, Wright K & Rangan A (2021) Effectiveness of interventions for the management of primary frozen shoulder. Bone & Joint Open, 2(9), 773-784.
Rangan A, Brealey SD, Keding A, Corbacho B, Northgraves M, Kottam L, Goodchild L, Srikesavan C, Rex S, Charalambous CP , Hanchard N et al (2020) Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial. The Lancet, 396(10256), 977-989.
Hind D, Parkin J, Whitworth V, Rex S, Young T, Hampson L, Sheehan J, Maguire C, Cantrill H, Scott E , Epps H et al (2017) Aquatic therapy for children with Duchenne muscular dystrophy: a pilot feasibility randomised controlled trial and mixed-methods process evaluation. HEALTH TECHNOLOGY ASSESSMENT, 21(27).
Julious SA, Horspool MJ, Davis S, Bradburn M, Norman P, Shephard N, Cooper CL, Smithson WH, Boote J, Elphick H , Loban A et al (2016) PLEASANT: Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term - a cluster randomised controlled trial and economic evaluation.. Health Technology Assessment, 20(93), 1-154.
Mountain GA, Hind D, Gossage-Worrall R, Walters SJ, Duncan R, Newbould L, Rex S, Jones C, Bowling A, Cattan M , Cairns A et al (2014) ‘Putting Life in Years’ (PLINY) telephone friendship groups research study: pilot randomised controlled trial. Trials, 15(1).
Sharples L, Papachristofi O, Rex S & Landau S () Exploring mechanisms of action in clinical trials of complex surgical interventions using mediation analysis. Clinical Trials, 174077452094764-174077452094764.
Brealey S, Northgraves M, Kottam L, Keding A, Corbacho B, Goodchild L, Srikesavan C, Rex S, Charalambous CP, Hanchard N , Armstrong A et al () Surgical treatments compared with early structured physiotherapy in secondary care for adults with primary frozen shoulder: the UK FROST three-arm RCT. Health Technology Assessment, 24(71), 1-162.

Conference proceedings papers

Rex S, Chang JY, Bradburn M, Akehurst R & Latimer N (2022) RWD66 Application of the target trial framework for estimating comparative effectiveness using real-world data-a systematic review. Value in Health, Vol. 25(12 Suppl) (pp S461-S461). Vienna, Austria, 6 November 2022 - 9 November 2022.
Rex SS, White D, Chatters R & Bradburn M (2019) Factors that affect attrition in RCTs for the treatment of depression. Trials, Vol. 20(Suppl 1) (pp 53-54). Brighton, UK, 6 October 2019 - 9 October 2019.
Sharples L, Rex S & Papachristofi O (2019) Exploring mechanisms of action in clinical trials of complex interventions using mediation. TRIALS, Vol. 20

All publications

Journal articles

Horner D, Rex S, Reynard C, Bursnall M, Bradburn M, de Wit K, Goodacre S & Hunt BJ (2023) Accuracy of efficient data methods to determine the incidence of hospital-acquired thrombosis and major bleeding in medical and surgical inpatients: a multicentre observational cohort study in four UK hospitals. BMJ Open, 13(2).
Thornhill M, Crum A, Rex S, Campbell R, Stone T, Bradburn M, Fibisan V, Dayer M, Prendergast B, Lockhart P , Baddour P et al (2022) Infective endocarditis following invasive dental procedures: IDEA case-crossover study. Health Technology Assessment, 26(28).
Thornhill M, Crum A, Rex S, Stone T, Campbell R, Bradburn M, Fibisan V, Lockhart P, Springer B, Baddour L & Nicholl J (2022) Analysis of prosthetic joint infections following invasive dental procedures in England. JAMA Network Open, 5(1). View this article in WRRO
Rex SS, Kottam L, McDaid C, Brealey S, Dias J, Hewitt CE, Keding A, Lamb SE, Wright K & Rangan A (2021) Effectiveness of interventions for the management of primary frozen shoulder. Bone & Joint Open, 2(9), 773-784.
Rangan A, Brealey SD, Keding A, Corbacho B, Northgraves M, Kottam L, Goodchild L, Srikesavan C, Rex S, Charalambous CP , Hanchard N et al (2020) Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial. The Lancet, 396(10256), 977-989.
Hind D, Parkin J, Whitworth V, Rex S, Young T, Hampson L, Sheehan J, Maguire C, Cantrill H, Scott E , Epps H et al (2017) Aquatic therapy for children with Duchenne muscular dystrophy: a pilot feasibility randomised controlled trial and mixed-methods process evaluation. HEALTH TECHNOLOGY ASSESSMENT, 21(27).
Hind D, Parkin J, Whitworth V, Rex S, Young T, Hampson L, Sheehan J, Maguire C, Cantrill H, Scott E , Epps H et al (2017) Aquatic therapy for boys with Duchenne muscular dystrophy (DMD): an external pilot randomised controlled trial. Pilot and Feasibility Studies, 3, 16-16. View this article in WRRO
Julious SA, Horspool MJ, Davis S, Bradburn M, Norman P, Shephard N, Cooper CL, Smithson WH, Boote J, Elphick H , Loban A et al (2016) PLEASANT: Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term - a cluster randomised controlled trial and economic evaluation.. Health Technology Assessment, 20(93), 1-154.
Hind D, Mountain G, Gossage-Worrall R, Walters SJ, Duncan R, Newbould L, Rex S, Jones C, Bowling A, Cattan M , Cairns A et al (2014) Putting Life in Years (PLINY): a pilot randomised controlled trial and mixed-methods process evaluation of telephone friendship groups for community living older adults. Public Health Research, 2(7).
Mountain GA, Hind D, Gossage-Worrall R, Walters SJ, Duncan R, Newbould L, Rex S, Jones C, Bowling A, Cattan M , Cairns A et al (2014) ‘Putting Life in Years’ (PLINY) telephone friendship groups research study: pilot randomised controlled trial. Trials, 15(1).
Horner DE, Davis S, Pandor A, Shulver H, Goodacre S, Hind D, Rex S, Gillett M, Bursnall M, Griffin X , Holland M et al () Evaluation of venous thromboembolism risk assessment models for hospital inpatients: the VTEAM evidence synthesis. Health Technology Assessment, 1-166.
Sharples L, Papachristofi O, Rex S & Landau S () Exploring mechanisms of action in clinical trials of complex surgical interventions using mediation analysis. Clinical Trials, 174077452094764-174077452094764.
Brealey S, Northgraves M, Kottam L, Keding A, Corbacho B, Goodchild L, Srikesavan C, Rex S, Charalambous CP, Hanchard N , Armstrong A et al () Surgical treatments compared with early structured physiotherapy in secondary care for adults with primary frozen shoulder: the UK FROST three-arm RCT. Health Technology Assessment, 24(71), 1-162.

Conference proceedings papers

Rex S, Chang JY, Bradburn M, Akehurst R & Latimer N (2022) RWD66 Application of the target trial framework for estimating comparative effectiveness using real-world data-a systematic review. Value in Health, Vol. 25(12 Suppl) (pp S461-S461). Vienna, Austria, 6 November 2022 - 9 November 2022.
Rex SS, White D, Chatters R & Bradburn M (2019) Factors that affect attrition in RCTs for the treatment of depression. Trials, Vol. 20(Suppl 1) (pp 53-54). Brighton, UK, 6 October 2019 - 9 October 2019.
Sharples L, Rex S & Papachristofi O (2019) Exploring mechanisms of action in clinical trials of complex interventions using mediation. TRIALS, Vol. 20
Elphick H, Horspool M, Davis S, Bradburn M, Norman P, Shephard N, Cooper C, Smithson WH, Boote J, Loban A , Franklin M et al (2016) LATE-BREAKING ABSTRACT: PLEASANT: Preventing and lessening exacerbations of asthma in school-age children associated with a new term. 1.6 General Practice and Primary Care