Rachel

Waller

Journal articles

• Vazquez-Villaseñor I, Benson B, Richardson CD, Waller R, Castelli LM, Simpson JE, Matthews FE, Brayne C & Wharton SB (2026) Senescence markers and associated transcriptomic changes are expressed at early stages of Alzheimer’s neuropathology but are not independently related to dementia. International Journal of Molecular Sciences, 27(15). View this article in WRRO
• Almansouri T, Waller R, Wharton SB, Heath PR, Matthews FE, Brayne C, van Eeden F & Simpson JE (2024) The microglial transcriptome of age-associated deep subcortical white matter lesions suggests a neuroprotective response to blood–brain barrier dysfunction. International Journal of Molecular Sciences, 25(8). View this article in WRRO
• Waller R, Bury JJ, Appleby-Mallinder C, Wyles M, Loxley G, Babel A, Shekari S, Kazoka M, Wollff H, Al-Chalabi A , Heath PR et al (2024) Establishing mRNA and microRNA interactions driving disease heterogeneity in amyotrophic lateral sclerosis patient survival. Brain Communications, 6(1). View this article in WRRO
• Waller R, Hase Y, Simpson JE, Heath PR, Wyles M, Kalaria RN & Wharton SB (2023) Transcriptomic profiling reveals discrete poststroke dementia neuronal and gliovascular signatures. Translational Stroke Research, 14(3), 383-396. View this article in WRRO
• Hase Y, Ameen‐Ali KE, Waller R, Simpson JE, Stafford C, Mahesh A, Ryan L, Pickering L, Bodman C, Hase M , Boche D et al (2022) Differential perivascular microglial activation in the deep white matter in vascular dementia developed post‐stroke. Brain Pathology, 32(6). View this article in WRRO
• Waller R, Narramore R, Simpson JE, Heath PR, Verma N, Tinsley M, Barnes J, Haris H, Henderson FE, Matthews FE , Richardson CD et al (2021) Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to alzheimer’s and small vessel disease pathologies. Brain Pathology, 31(3). View this article in WRRO
• Waller R, Mandeya M, Viney E, Simpson JE & Wharton SB (2020) Histological characterization of interneurons in Alzheimer's disease reveals a loss of somatostatin interneurons in the temporal cortex. Neuropathology, 40(4), 336-346. View this article in WRRO
• Fadul MM, Garwood CJ, Waller R, Garrett N, Heath PR, Matthews FE, Brayne C, Wharton SB & Simpson JE (2020) NDRG2 expression correlates with neurofibrillary tangles and microglial pathology in the ageing brain. International Journal of Molecular Sciences, 21(1). View this article in WRRO
• Wharton SB, Verber NS, Wagner BE, Highley JR, Fillingham DJ, Waller R, Strand K, Ince PG & Shaw PJ (2019) Combined FUS+ basophilic inclusion body disease and atypical tauopathy presenting with an ALS/MND-plus phenotype. Neuropathology and Applied Neurobiology, 45(6), 586-596. View this article in WRRO
• Waller R, Baxter L, Fillingham DJ, Coelho S, Pozo JM, Mozumder M, Frangi AF, Ince PG, Simpson JE & Highley JR (2019) Iba-1-/CD68+ microglia are a prominent feature of age-associated deep subcortical white matter lesions.. PLoS One, 14(1). View this article in WRRO
• Waller R, Wyles M, Heath PR, Kazoka M, Wollff H, Shaw P & Kirby J (2018) Small RNA sequencing of sporadic amyotrophic lateral sclerosis cerebrospinal fluid reveals differentially expressed miRNAs related to neural and glial activity. Frontiers in Neuroscience, 11. View this article in WRRO
• Waller R, Goodall EF, Milo M, Cooper-Knock J, Da Costa M, Hobson E, Kazoka M, Wollff H, Heath PR, Shaw P & Kirby J (2017) Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS). Neurobiology of Aging, 55, 123-131. View this article in WRRO
• Waller R, Woodroofe MN, Wharton SB, Ince PG, Francese S, Heath PR, Cudzich-Madry A, Thomas R, Rounding N, Sharrack B & Simpson JE (2016) Gene expression profiling of the astrocyte transcriptome in multiple sclerosis normal appearing white matter reveals a neuroprotective role. Journal of Neuroimmunology, 299, 139-146. View this article in WRRO
• Al Sultan A, Waller R, Heath P & Kirby J (2016) The Genetics of Amyotrophic Lateral Sclerosis: Current Insights. Degenerative Neurological and Neuromuscular Disease, 2016(6), 49-64. View this article in WRRO
• Waller R, Woodroofe MN, Francese S, Heath PR, Wharton SB, Ince PG, Sharrack B & Simpson JE (2012) Isolation of enriched glial populations from post-mortem human CNS material by immuno-laser capture microdissection. Journal of Neuroscience Methods, 208(2), 108-113.
• Waller R, Murphy M, Garwood C, Jennings L, Heath P, Chambers A, Matthews F, Brayne C, Ince P, Wharton S & Simpson J () Metallothionein‐I/II expression associates with the astrocyte DNA damage response and not Alzheimer‐type pathology in the aging brain. Glia. View this article in WRRO

Conference proceedings

• Waller R, Heath PR, Woodroofe MN, Francese S, Wharton SB, Ince PG, Sharrack B & Simpson JE (2012) Microarray analysis of the astrocyte transcriptome in normal appearing white matter in multiple sclerosis. JOURNAL OF NEUROIMMUNOLOGY, Vol. 253(1-2) (pp 54-54)