Duncan Chambers
BSc, MSc
School of Medicine and Population Health
Research Fellow
d.chambers@sheffield.ac.uk
+44 114 222 5159
+44 114 222 5159
+44 114 222 0749
(Fax)
2037, 2nd Floor, Regent Court (ScHARR)
Full contact details
Duncan Chambers
School of Medicine and Population Health
2037, 2nd Floor
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
School of Medicine and Population Health
2037, 2nd Floor
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
- Profile
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I joined the University of Sheffield in September 2014 to support a rapid evidence synthesis programme commissioned by the National Institute for Health Research (NIHR) Health and Social Care Delivery Research (HS&DR) Programme. In addition to this programme, I have led or contributed to numerous evidence synthesis and health technology assessment projects. I am an active member of the ScHARR ethics committee.
- Research interests
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My research interests are concerned with supporting the use of systematic reviews in evidence-informed decision-making, particularly around urgent and emergency care and social care. This includes methods for rapid reviews, overviews of systematic reviews and engagement with decision-makers, clinicians, patients and the public.
Current projects:
- Publications
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Show: Featured publications All publications
Featured publications
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All publications
Journal articles
- A systematic review of international performance indicators and metrics relevant to UK general practice. BMJ Open Quality, 14(4). View this article in WRRO
- A rapid review of the causes of diagnostic and treatment delays for tuberculosis in low burden countries. Journal of Public Health. View this article in WRRO
- The acceptability of blood spot screening and genome sequencing in newborn screening: a systematic review examining evidence and frameworks. Health Technology Assessment. View this article in WRRO
- Interventions to minimise hospital winter pressures related to discharge planning and integrated care: a rapid mapping review of UK evidence. Health and Social Care Delivery Research, 12(31). View this article in WRRO
- Signposting services in the UK: enhanced support or service diversion for people with health and social care needs: a rapid realist synthesis. Journal of Integrated Care, 32(5), 99-108. View this article in WRRO
- Pharmacist-led primary care interventions to promote medicines optimisation and reduce overprescribing: a systematic review of UK studies and initiatives. BMJ Open, 14. View this article in WRRO
- Signposting services for people with health and care needs: a rapid realist review. Health and Social Care Delivery Research, 12(26). View this article in WRRO
- Factors within the clinical encounter that impact upon risk assessment within child and adolescent mental health services: a rapid realist synthesis. Health and Social Care Delivery Research, 12(1). View this article in WRRO
- A systematic review case study of urgent and emergency care configuration found citation searching of Web of Science and Google Scholar of similar value. Health Information and Libraries Journal, 41(2), 166-181. View this article in WRRO
- Reducing unplanned hospital admissions from care homes: a systematic review. Health and Social Care Delivery Research, 11(18). View this article in WRRO
- Assessment and management pathways of older adults with mild cognitive impairment : descriptive review and critical interpretive synthesis. Health and Social Care Delivery Research, 10(10), 1-150.
- Recognition of risk and prevention in safeguarding of children and young people: a mapping review and component analysis of service development interventions aimed at health and social care professionals. BMC Health Services Research, 21.
- Synthesis for health services and policy : case studies in the scoping of reviews. Health Services and Delivery Research, 9(15), 1-84. View this article in WRRO
- Effects of increased distance to urgent and emergency care facilities resulting from health services reconfiguration : a systematic review. Health Services and Delivery Research, 8(31), 1-86. View this article in WRRO
- Effects of service changes affecting distance / time to access urgent and emergency care facilities on patient outcomes : a systematic review. BMC Medicine, 18(1). View this article in WRRO
- Implementation of interventions to reduce preventable hospital admissions for cardiovascular or respiratory conditions : an evidence map and realist synthesis. Health Services and Delivery Research, 8(2), 1-148.
- Access to primary and community health-care services for people 16 years and over with intellectual disabilities: a mapping and targeted systematic review. Health Services and Delivery Research, 8(5), 1-142. View this article in WRRO
- Interventions to manage use of the emergency and urgent care system by people from vulnerable groups : a mapping review. Health Services and Delivery Research, 7(33), 1-46.
- Digital and online symptom checkers and assessment services for urgent care to inform a new digital platform : a systematic review. Health Services and Delivery Research, 7(29), 1-88. View this article in WRRO
- Digital and online symptom checkers and health assessment/triage services for urgent health problems: systematic review. BMJ Open, 9(8). View this article in WRRO
- Towards greater understanding of implementation during systematic reviews of complex healthcare interventions: the framework for implementation transferability applicability reporting (FITAR). BMC Medical Research Methodology, 19. View this article in WRRO
- Evidence to support delivery of effective health services: a responsive programme of rapid evidence synthesis. Evidence & Policy, 17(1), 173-187. View this article in WRRO
- Understanding new models of integrated care in developed countries: a systematic review. Health Services and Delivery Research, 6(29). View this article in WRRO
- What Is the Burden of Immunoglobulin Replacement Therapy in Adult Patients With Primary Immunodeficiencies? A Systematic Review. Frontiers in Immunology, 9. View this article in WRRO
- The effects of integrated care: a systematic review of UK and international evidence. BMC Health Services Research, 18(1). View this article in WRRO
- What evidence is there for the identification and management of frail older people in the emergency department? A systematic mapping review. Health Services and Delivery Research, 6(16). View this article in WRRO
- Enhanced recovery after elective caesarean: a rapid review of clinical protocols, and an umbrella review of systematic reviews. BMC Pregnancy and Childbirth, 17(1). View this article in WRRO
- Degarelix for Treating Advanced Hormone-Dependent Prostate Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics , 35(7), 717-726. View this article in WRRO
- Socioeconomic inequalities in mortality, morbidity and diabetes management for adults with type 1 diabetes: a systematic review.. PLoS One, 12(5). View this article in WRRO
- Evolocumab for Treating Primary Hypercholesterolaemia and Mixed Dyslipidaemia: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.. PharmacoEconomics, 35(5), 537-547. View this article in WRRO
- Does access to a demand-led evidence briefing service improve uptake and use of research evidence by health service commissioners? A controlled before and after study.. Implementation Science, 12(1).
- Effects of a demand-led evidence briefing service on the uptake and use of research evidence by commissioners of health services: a controlled before-and-after study. Health Services and Delivery Research, 5(5). View this article in WRRO
- Interventions to improve contact tracing for tuberculosis in specific groups and in wider populations: an evidence synthesis. Health Services and Delivery Research, 5(1), 1-102. View this article in WRRO
- Evidence for models of diagnostic service provision in the community: literature mapping exercise and focused rapid reviews. Health Services and Delivery Research, 4(35), 1-362.
- Cabazitaxel for Hormone-Relapsed Metastatic Prostate Cancer Previously Treated With a Docetaxel-Containing Regimen: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.. Pharmacoeconomics. View this article in WRRO
- Service user engagement in health service reconfiguration: a rapid evidence synthesis. Journal of Health Services Research & Policy, 21(3), 195-205.
- What is the evidence for the effectiveness, appropriateness and feasibility of group clinics for patients with chronic conditions? A systematic review. Health Services and Delivery Research, 3(46). View this article in WRRO
- What evidence is there on the effectiveness of different models of delivering urgent care? A rapid review. Health Services and Delivery Research, 3(43).
- Effects of a demand-led evidence briefing service on the uptake and use of research evidence by commissioners of health services: protocol for a controlled before and after study. Implementation Science, 10. View this article in WRRO
- Effectiveness and implementation of enhanced recovery after surgery programmes: a rapid evidence synthesis. BMJ Open, 4(7), e005015-e005015.
- An overview and methodological assessment of systematic reviews and meta-analyses of enhanced recovery programmes in colorectal surgery. BMJ Open, 4(5), e005014-e005014.
- Behaviour change interventions to promote prescribing of generic drugs: a rapid evidence synthesis and systematic review. BMJ Open, 4(5), e004623-e004623.
- Immediate versus sustained effects: interrupted time series analysis of a tailored intervention. Implementation Science, 8(1).
- Exploring the feasibility of Conjoint Analysis as a tool for prioritizing innovations for implementation. Implementation Science, 8(1).
- Challenges in identifying barriers to adoption in a theory-based implementation study: lessons for future implementation studies. BMC Health Services Research, 12(1).
- A framework for production of systematic review based briefings to support evidence-informed decision-making. Systematic Reviews, 1(1).
- Use of evidence from systematic reviews to inform commissioning decisions: a case study. Evidence & Policy, 8(2), 141-148.
- Maximizing the Impact of Systematic Reviews in Health Care Decision Making: A Systematic Scoping Review of Knowledge-Translation Resources. Milbank Quarterly, 89(1), 131-156.
- Sugammadex for reversal of neuromuscular block after rapid sequence intubation: a systematic review and economic assessment. British Journal of Anaesthesia, 105(5), 568-575.
- Sugammadex compared with neostigmine/glycopyrrolate for routine reversal of neuromuscular block: a systematic review and economic evaluation. British Journal of Anaesthesia, 105(5), 558-567.
- Glycopeptide vs. Non-Glycopeptide Antibiotics for Prophylaxis of Surgical Site Infections: A Systematic Review. Surgical Infections, 11(5), 455-462.
- Translating research into practice in Leeds and Bradford (TRiPLaB): a protocol for a programme of research. Implementation Science, 5(1).
- Use of Non-randomised Evidence Alongside Randomised Trials in a Systematic Review of Endovascular Aneurysm Repair: Strengths and Limitations. Journal of Vascular Surgery, 51(1), 283-283.
- Use of Non-randomised Evidence Alongside Randomised Trials in a Systematic Review of Endovascular Aneurysm Repair: Strengths and Limitations. European Journal of Vascular and Endovascular Surgery, 39(1), 26-34.
- An economic model for the prevention of MRSA infections after surgery: non-glycopeptide or glycopeptide antibiotic prophylaxis?. The European Journal of Health Economics, 11(1), 57-66.
- Not only randomized controlled trials, but also case series should be considered in systematic reviews of rapidly developing technologies. Journal of Clinical Epidemiology, 62(12), 1253-1260.e4.
- Risk factors for chronic fatigue syndrome/myalgic encephalomyelitis: a systematic scoping review of multiple predictor studies. Psychological Medicine, 38(7), 915-926.
- Interventions for the Treatment, Management and Rehabilitation of Patients with Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis: An Updated Systematic Review. Journal of the Royal Society of Medicine, 99(10), 506-520.
- Evolocumab for Treating Primary Hypercholesterolaemia and Mixed Dyslipidaemia: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics.
- Service user engagement and health service reconfiguration: a rapid evidence synthesis. Health Services and Delivery Research, 3(17). View this article in WRRO
- Initiatives to reduce length of stay in acute hospital settings: a rapid synthesis of evidence relating to enhanced recovery programmes. Health Services and Delivery Research, 2(21), 1-118.
- Social Network Analysis in Healthcare Settings: A Systematic Scoping Review. PLoS ONE, 7(8), e41911-e41911.
- Sugammadex for the reversal of muscle relaxation in general anaesthesia: a systematic review and economic assessment. Health Technology Assessment, 14(39).
- Endovascular stents for abdominal aortic aneurysms: a systematic review and economic model. Health Technology Assessment, 13(48).
- Cost-effectiveness of radiofrequency catheter ablation for the treatment of atrial fibrillation in the United Kingdom. Heart, 95(7), 542-549.
- Curative catheter ablation in atrial fibrillation and typical atrial flutter: systematic review and economic evaluation. Health Technology Assessment, 12(34).
- A systematic review and economic model of switching from non-glycopeptide to glycopeptide antibiotic prophylaxis for surgery. Health Technology Assessment, 12(1).
Conference proceedings
- P18 Accuracy of screening tests for mild cognitive impairment or dementia in the general population: a systematic mapping review. Journal of Epidemiology and Community Health, Vol. 79(Suppl 1) (pp A47.1-A47). Bradford, UK, 10 September 2025 - 10 September 2025. View this article in WRRO
- OP34 The acceptability of blood spot screening and genome sequencing in newborn screening: a systematic review of evidence and frameworks*. Journal of Epidemiology and Community Health
- OP34 The acceptability of blood spot screening and genome sequencing in newborn screening: a systematic review of evidence and frameworks*. SSM Annual Scientific Meeting (pp A12.1-A12)
- P27 Evidence gap maps: A policy makers tool for navigating the evidence landscape. A case study of employment and health from the SIPHER (systems science in public health and health economics research) project. SSM Annual Scientific Meeting (pp A66.2-A67)
- Understanding new models of integrated care: a systematic review examining pathways of change, outcomes and impacts. International Journal of Integrated Care, Vol. 18(s2) (pp 2-2). Utrecht, Netherlands, 23 May 2018 - 23 May 2018. View this article in WRRO
- Limitations of Internet searching for understanding the commissioning and delivery of health services: findings from a systematic review of diagnostic ultrasound services. Journal of Epidemiology and Community Health, Vol. 70(Suppl 1) (pp A96-A96). University of York, UK, 14 September 2016 - 14 September 2016. View this article in WRRO
Reports
- How do risk assessments for self harm and suicide in crisis or emergency settings change the clinical encounter and outcomes for children and adolescents?: realist synthesis and mapping review View this article in WRRO
- Organisation-wide interventions to promote the health and well-being of healthcare staff during periods of increased demand: a systematic review
- Rapid evidence review : challenges to implementing digital and data-driven technologies in health and social care View this article in WRRO
- Recognition of risk and prevention in safeguarding of children and young people : a mapping review and component analysis of interventions aimed at health and social care professionals. View this article in WRRO
- ECASS health economic feasibility study View this article in WRRO
- Systematic review of the evidence on housing interventions for ‘housing-vulnerable’ adults and its relationship to wellbeing View this article in WRRO
- The Diversity Dividend: does a more diverse and inclusive research community produce better biomedical and health research? View this article in WRRO
- NIHR HS&DR evidence synthesis centres: achievements and learning from the first three year programme, 2014–2017 View this article in WRRO
- What evidence is there for the identification and management of frail older people in the emergency department? A systematic mapping review View this article in WRRO
- Degarelix for treating advanced hormone-dependent
Prostate cancer [ID590]
Spinal cord compression associated with hormonal
therapy in men with hormone-dependent metastatic
prostate cancer: a systematic review and economic
assessment
Working papers
- Review of diversity and inclusion literature and an evaluation of methodologies and metrics relating to health research. View this article in WRRO
- A systematic review of international performance indicators and metrics relevant to UK general practice. BMJ Open Quality, 14(4). View this article in WRRO
- Teaching interests
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My teaching interests lie in systematic reviews and critical appraisal of research evidence.
- Professional activities and memberships
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Peer reviewer for the Cochrane Wounds Group and various international journals.