News

Nerve signals

Novel treatment for motor neuron disease to be trialled in humans

University of Sheffield researchers are taking part in an investigational drug trial, designed to target one of the most important genetic drivers of MND, the UNC13A protein.

A plastic model of the brain anatomy

Novel clinical trial platform could dramatically speed up search for Motor Neuron Disease treatments

A University of Sheffield researcher was one of the lead investigators into a novel trial design that could mean faster results in the race to find effective treatments for Motor Neuron Disease.
Celebrating Dr Johnathan Cooper-Knock's appointment as the first MND Association Rob Burrow Professor
Credit: MND Association

Sheffield neurologist becomes first MND Association Rob Burrow Professor

A world-leading neurologist and geneticist at the University of Sheffield has been appointed to the first Rob Burrow Professorship in Translational Neurobiology named after the late rugby league legend Rob Burrow CBE.

Architect's rendering of proposed new SITraN sister facility
Architect's rendering of proposed new SITraN sister facility. Credit: Bond Bryan Architects

University of Sheffield reaches £14m to further groundbreaking neuroscience research

Fundraising success as University of Sheffield reaches £14m to further groundbreaking neuroscience research.
Nerve cells

Scientists discover how to prevent death of nerve cells in most common genetic forms of MND and dementia

Scientists have found a novel way to block the transportation of mutant RNA and subsequent production of toxic repeat proteins which lead to the death of nerve cells in the most common subtypes of MND and FTD.
L-R: Professor Sharrack and Professor Snowden at the therapeutic apheresis unit, where stem cells are collected, at Sheffield Teaching Hospitals NHS Foundation Trust

MS patients could be offered stem cell transplants as a first-line treatment in new world-first trial

A world-first trial is investigating if stem cell transplantation could be used in patients with aggressive multiple sclerosis (MS) as a first-line treatment.
Lumbar Puncture - treatment for MND

Promising MND drug helps slow disease progression and benefits patients physically

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.
Photo of the Golden Globe Race 2022 banner

Golden Globe Race 2022 - raising money for SITraN

And they’re off! On Sunday 4th September 23 skippers set sail on the prestigious Golden Globe Race. Fundraising for the University of Sheffield’s Institute for Translational Neuroscience, these skippers won’t return for at least 9 months!
Neurons Cells System - 3d rendered image of Interconnected Neurons with electrical pulses. Conceptual medical animation

Sheffield scientists benefit from £4.25 million to kick start MND research institute

Researchers from the University of Sheffield’s Institute for Translational Neuroscience (SITraN) have been awarded part of a new £4.25 million grant that seeks to discover meaningful MND treatments within years, not decades.