This study explores the experiences of palliative and end of life care for patients with mesothelioma from the perspective of bereaved family caregivers. It concludes that greater opportunity for open, one-to-one communication between family caregivers and healthcare professionals is vital to enable the caregiver to prepare for what lies ahead at the end of life and prevent feelings of abandonment after the death of the patient. Improved care co-ordination and partnership working are essential for supporting both patient and caregiver at the end of life.