Dr Xinshan Li

School of Mechanical, Aerospace and Civil Engineering

Senior Lecturer

xinshan.li@sheffield.ac.uk
+44 114 222 7786

Sir Frederick Mappin Building

Full contact details

Dr Xinshan Li
School of Mechanical, Aerospace and Civil Engineering
Sir Frederick Mappin Building
Mappin Street
Sheffield
S1 3JD

Profile

Dr Xinshan (Shannon) Li obtained her PhD in Bioengineering from the Auckland Bioengineering Institute in 2011. Her thesis focused on the biomechanics of pelvic floor muscles during childbirth.

Xinshan joined the Department of Computer Science at the University of Sheffield in 2011, working on cell-based modelling for skin inflammation in collaboration with P&G. In 2013, Xinshan joined the Department of Mechanical Engineering as a lecturer.

Xinshan's main research interest is in continuum modelling of the musculoskeletal system. She has extensive experience in creating computer models of bones and skeletal muscles based on medical images. These models are used in a wide range of applications from investigating children’s bone mechanics, to predicting the risk of fracture in elderly, and obstetrics and gynaecology.

Research interests

Biomechanics of paediatric bone in the application of child abuse
Risk of fracture prediction in adults using finite element approach
Biomechanics of the female pelvic floor muscles and the cervix

Publications

Books

(2022) Computational Biomechanics for Medicine. Springer International Publishing.
Nielsen PMF, Nash MP, Miller K, Wittek A & Li X (2022) Preface.

Journal articles

Henson WH, Li X, Lin Z, Guo L, Mazzá C & Dall’Ara E (2024) Automatic segmentation of lower limb muscles from MR images of post-menopausal women based on deep learning and data augmentation. PLOS ONE, 19(4). View this article in WRRO
Li J, Viceconti M, Li X, Bhattacharya P, Naimark DMJ & Osseyran A (2023) Cost-Effectiveness Analysis of CT-Based Finite Element Modeling for Osteoporosis Screening in Secondary Fracture Prevention: An Early Health Technology Assessment in the Netherlands. MDM Policy & Practice, 8(2).
Altai Z, Montefiori E & Li X (2023) Effect of muscle forces on femur during level walking using a virtual population of older women. Methods in molecular biology (Clifton, N.J.), MIMB 2716, 335-349. View this article in WRRO
Benemerito I, Griffiths W, Allsopp J, Furnass W, Bhattacharya P, Li X, Marzo A, Wood S, Viceconti M & Narracott A (2021) Delivering computationally-intensive Digital Patient applications to the clinic: an exemplar solution to predict femoral bone strength from CT data. Computer Methods and Programs in Biomedicine, 106200-106200.
Taylor M, Viceconti M, Bhattacharya P & Li X (2021) Finite element analysis informed variable selection for femoral fracture risk prediction. Journal of the Mechanical Behavior of Biomedical Materials. View this article in WRRO
Altai Z, Montefiori E, van Veen B, A. Paggiosi M, McCloskey EV, Viceconti M, Mazzà C & Li X (2021) Femoral neck strain prediction during level walking using a combined musculoskeletal and finite element model approach. PLoS ONE, 16(2). View this article in WRRO
Winsor C, Li X, Qasim M, Henak CR, Pickhardt PJ, Ploeg H & Viceconti M (2021) Evaluation of patient tissue selection methods for deriving equivalent density calibration for femoral bone quantitative CT analyses. Bone, 143.
Barbone AS, Li X, Arabin B, Kira Y, Jani JC & Cannie MM (2020) Preliminary modeling of effective positioning of Arabin cerclage pessary in women at high risk of preterm birth. Ultrasound in Obstetrics & Gynecology, 55(4), 557-558.
Altai Z, Qasim M, Li X & Viceconti M (2019) The effect of boundary and loading conditions on patient classification using finite element predicted risk of fracture. Clinical Biomechanics, 68, 137-143. View this article in WRRO
Castro APG, Altai Z, Offiah AC, Shelmerdine SC, Arthurs OJ, Li X & Lacroix D (2019) Finite element modelling of the developing infant femur using paired CT and MRI scans. PLoS ONE, 14(6). View this article in WRRO
Altai Z, Viceconti M, Offiah AC & Li X (2018) Investigating the mechanical response of paediatric bone under bending and torsion using finite element analysis. Biomechanics and Modeling in Mechanobiology, 17(4), 1001-1009. View this article in WRRO
Viceconti M, Qasim M, Bhattacharya P & Li X (2018) Correction to: Are CT-Based Finite Element Model Predictions of Femoral Bone Strength Clinically Useful?. Current Osteoporosis Reports.
Viceconti M, Qasim M, Bhattacharya P & Li X (2018) Are CT-Based Finite Element Model Predictions of Femoral Bone Strengthening Clinically Useful?. Current Osteoporosis Reports, 16(3), 216-223. View this article in WRRO
Yan X, Kruger JA, Li X, Nielsen PMF & Nash MP (2016) Modeling the second stage of labor. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 8(6), 506-516.
Scarton A, Sawacha Z, Cobelli C & Li X (2016) Towards the generation of a parametric foot model using principal component analysis: A pilot study. Medical Engineering & Physics, 38(6), 547-559.
Qasim M, Farinella G, Zhang J, Li X, Yang L, Eastell R & Viceconti M (2016) Patient-specific finite element estimated femur strength as a predictor of the risk of hip fracture: the effect of methodological determinants. Osteoporosis International, 27(9), 2815-2822. View this article in WRRO
Li X, Viceconti M, Cohen MC, Reilly GC, Carré MJ & Offiah AC (2015) Developing CT based computational models of pediatric femurs. Journal of Biomechanics, 48(10), 2034-2040. View this article in WRRO
Chen Y, Pani M, Taddei F, Mazzà C, Li X & Viceconti M (2014) Large-Scale Finite Element Analysis of Human Cancellous Bone Tissue Micro Computer Tomography Data: A Convergence Study. Journal of Biomechanical Engineering, 136(10). View this article in WRRO
Li X, Upadhyay AK, Bullock AJ, Dicolandrea T, Xu J, Binder RL, Robinson MK, Finlay DR, Mills KJ, Bascom CC , Kelling CK et al (2013) Skin stem cell hypotheses and long term clone survival--explored using agent-based modelling.. Sci Rep, 3, 1904. View this article in WRRO
Li X, Kruger JA, Nash MP & Nielsen PMF (2011) Anisotropic effects of the levator ani muscle during childbirth.. Biomech Model Mechanobiol, 10(4), 485-494.
Li X, Kruger JA, Nash MP & Nielsen PMF (2010) Effects of nonlinear muscle elasticity on pelvic floor mechanics during vaginal childbirth.. J Biomech Eng, 132(11), 111010.
Li X, Kruger JA, Nash MP & Nielsen PMF (2010) Modeling childbirth: elucidating the mechanisms of labor.. Wiley Interdiscip Rev Syst Biol Med, 2(4), 460-470.
Li X, Kruger JA, Nash MP & Nielsen PMF (2010) Effects of fetal head motion on pelvic floor mechanics, 129-137.
Li X, Kruger JA, Chung J-H, Nash MP & Nielsen PMF (2008) Modelling childbirth: comparing athlete and non-athlete pelvic floor mechanics.. Med Image Comput Comput Assist Interv, 11(Pt 2), 750-757.
Li X, Kruger JA, Chung JH, Nash MP & Nielsen PMF (2008) Modelling the pelvic floor for investigating difficulties during childbirth. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 6916.
Sadeghian SM, Arthurs OJ, Li X, Lewis CL & Shefelbine SJ () Neonatal Hip Loading in Developmental Dysplasia: Finite Element Simulation of Proximal Femur Growth and Treatment. HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery.
Altai Z, Viceconti M, Li X & Offiah AC () Investigating rolling as mechanism for humeral fractures in non-ambulant infants : a preliminary finite element study. Clinical Radiology. View this article in WRRO
Anumba DOC, Gillespie S, Jha S, Abdi S, Kruger J, Taberner A, Nielsen PMF & Li X () Postnatal pelvic floor muscle stiffness measured by vaginal elastometry in women with obstetric anal sphincter injury : a pilot study. International Urogynecology Journal. View this article in WRRO

Chapters

Kruger JA, Yan X, Li X, Nielsen PMF & Nash MP (2016) Applications of Pelvic Floor Modeling and Simulation, Biomechanics of the Female Pelvic Floor (pp. 367-382). Elsevier

Conference proceedings papers

Tartarini D, Benemerito I, Narracott A, Li X, Richmond P & Marzo A (2021) pFIRE: parallel Framework for Image REgistration. Compbiomed Conference 2021
Anumba DOC, Gillespie S, Jha S, Abdi S, Kruger J & Li X (2017) High Pelvic Floor Muscle Stiffness Measured by Vaginal Elastometry Is a Risk Factor for Delayed Second Stage of Labour, Instrumental Vaginal Delivery and Pelvic Floor Damage. REPRODUCTIVE SCIENCES, Vol. 24 (pp 124A-124A)
Watton P, Gondwe C & Li X (2016) skeletal muscle mechanics: modelling the interaction between the microstructure and the environmental mechanical envelope. Proceedings of the 7th European Congress on Computational Methods in Applied Sciences and Engineering
Yan X, Kruger J, Li X, Nash M & Nielsen P (2013) MODELLING EFFECT OF BONY PELVIS ON CHILDBIRTH MECHANICS. NEUROUROLOGY AND URODYNAMICS, Vol. 32(6) (pp 531-532)

Datasets

Tai ZA, Viceconti M, Li X & Offiah A Data for the paper "Humeral Fractures in Non-Ambulant Infants: CT-Based Finite Element Investigation Indicates an Unlikely Mechanism ".
Tai ZA, Viceconti M, Offiah A & Li X Data for the paper "Investigating the mechanical response of paediatric bone under bending and torsion using finite element analysis".
Tai ZA, Montefiori E, Veen BV, Paggiosi M, McCloskey E, Viceconti M, Mazza C & Li X Femoral neck strain prediction during level walking using a combined musculoskeletal and finite element model approach.