Member Publications
Recent publications from members of the Bateson Centre.
Publications
Journal articles
- Risk of bias in machine learning and statistical models to predict height or weight: a systematic review in fetal and paediatric medicine. Diagnostic and Prognostic Research, 9(1). View this article in WRRO
- Re: Rebecca Voelker. What Is Prostate Cancer? JAMA. In press. https://doi.org/10.1001/jama.2025.10177. European Urology.
- Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study. European Urology Focus.
- RESECT: A Randomised Controlled Trial of Audit and Feedback in Non–muscle-invasive Bladder Cancer Surgery. European Urology.
- Additional Cover. Aging Cell, 24(12).
- Exciting Times in Urological Oncology: Rapid Advances and Greater Complexity Are Changing Practice and Improving Outcomes. European Urology Focus.
- Translational readthrough therapy for ADPKD induces polycystin1 expression and partially rescues functional deficits in PKD1 mutant cells. Scientific Reports, 15(1), 42746.
- TRIB3 Links Endoplasmic Reticulum Stress to Impaired Efferocytosis in Atherosclerosis. Circulation Research.
- Team familiarity: Renal, bladder and p;rostate cancer surgery outcomes with respect to team composition. European Urology Open Science, 81, S346-S346.
- Health-related quality of life in muscle invasive bladder cancer patients receiving radical surgery versus those who do not: A real-world survey. European Urology Open Science, 81, S413-S414.
- Non–muscle-invasive Bladder Cancer: Many New Options, If You Can Afford Them. European Urology.
- Evidence for improved DNA repair in long-lived bowhead whale. Nature. View this article in WRRO
- Oncogenic Ras activation in permissive somatic cells triggers rapid-onset phenotypic plasticity and elicits a tumor-promoting neutrophil response. Cell Reports, 44(11), 116478-116478.
- SAT-176 Pilot Data Collection From The New I-HH Registry For Surveillance Of Hypogonadotropic Hypogonadism, Implementation Of Best Practice Management And International Standardisation. Journal of the Endocrine Society, 9(Supplement_1).
- Correction: A subset of neutrophil phagosomes is characterised by pulses of Class I PI3K activity. Disease Models & Mechanisms, 18(10).
- #1977 Deep phenotyping predicts genotype and refines prognosis in lower risk ADPKD genotypes. Nephrology Dialysis Transplantation, 40(Supplement_3).
- EndoCompass project: research roadmap for adrenal and cardiovascular endocrinology. European Journal of Endocrinology, 193(Supplement_2), ii12-ii22. View this article in WRRO
- Revisiting Neoadjuvant Chemotherapy in Cisplatin-eligible Muscle-invasive Bladder Cancer. European Urology Oncology.
- Erdafitinib in Patients with High- and Intermediate-risk Non–muscle-invasive Bladder Cancer: Final Analysis of THOR-2 Study. European Urology.
- Interventions for patients with prostate cancer on active surveillance: a narrative review. BJU International. View this article in WRRO
- REN p.L16del Mutation Is Associated with a Milder In Vitro and Clinical Phenotype Compared with Other Signal Peptide Mutations. Journal of the American Society of Nephrology, 36(10S).
- Ward AdmiSsion of Haematuria, an Observational mUlticentre sTudy: patient-level analysis (WASHOUT). European Urology Open Science, 80, S8-S8.
- Monoallelic IFT140 variants causing childhood-onset autosomal dominant polycystic kidney disease. American Journal of Kidney Diseases. View this article in WRRO
- Genetic susceptibility and environmental risk factors in bladder cancer: evidence from the UK biobank. Bladder Cancer, 11(3). View this article in WRRO
- Fungal infections in focus: accelerating non-invasive imaging from preclinical insights to clinical breakthroughs. npj Imaging, 3(1). View this article in WRRO
- Renal, bladder and prostate cancer surgery outcomes with respect to team familiarity. BJU International. View this article in WRRO
- A guide to consumer-grade wearables in cardiovascular clinical care and population health for non-experts. npj Cardiovascular Health, 2(1). View this article in WRRO
- 3069MO Health-related quality of life (HRQoL) outcomes from the NIAGARA trial of perioperative durvalumab (D) plus neoadjuvant chemotherapy (NAC) in muscle-invasive bladder cancer (MIBC). Annals of Oncology, 36, S1588-S1588.
- LBA111 Randomized comparison of upfront magnetic resonance imaging versus transurethral resection for staging new bladder cancers: Final survival analysis from the BladderPath trial. Annals of Oncology, 36, S1767-S1767.
- Decoding the adaptive survival mechanisms of breast cancer dormancy. Oncogene, 44, 3759-3773. View this article in WRRO
- Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells. The Journal of Physiology. View this article in WRRO
- Microultrasonography-Guided vs MRI-Guided Biopsy for Prostate Cancer Diagnosis. JAMA, 334(7), 641-641.
- NANOG is repurposed after implantation to repress Sox2 and begin pluripotency extinction. The EMBO Journal, 44(19), 5337-5374. View this article in WRRO
- Ward AdmiSsion of Haematuria: an Observational mUlticentre sTudy (WASHOUT) – study protocol. BMJ Open, 15(8). View this article in WRRO
- Paired and solitary ionocytes in the zebrafish olfactory epithelium. Chemical Senses, 50. View this article in WRRO
- Senataxin regulates cisplatin resistance through an R-loop-mediated mechanism in HPV-associated head and neck cancer. iScience, 28(9). View this article in WRRO
- Steroid 21-hydroxylase deficiency dysregulates essential molecular pathways of metabolism and energy provision. Biology Open, 14(9). View this article in WRRO
- Leptin and adiponectin in children and young persons with congenital adrenal hyperplasia. European Journal of Endocrinology, 193(3), 329-339. View this article in WRRO
- Determining the importance of the stringent response for methicillin-resistant staphylococcus aureus virulence in vivo. The Journal of Infectious Diseases. View this article in WRRO
- Loneliness, social isolation, and effects on cognitive decline in patients with dementia: A retrospective cohort study using natural language processing. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 17(3). View this article in WRRO
- Longitudinal modelling of growth in neonates exposed to antenatal steroids to quantify associations with final height: a cohort study. Archives of Disease in Childhood. View this article in WRRO
- A subset of neutrophil phagosomes is characterised by pulses of Class I PI3K activity. Disease Models & Mechanisms, 18(9). View this article in WRRO
- Neuroprotection in Parkinson disease. Neurology and Therapy, 14(5), 1747-1767. View this article in WRRO
- A conceptual model of factors potentially influencing prescribing decisions for chronic conditions: an overview of systematic reviews. BMC Medicine, 23(1). View this article in WRRO
- Quantifying association of early proteinuria and estimated glomerular filtration rate changes with long-term kidney failure in C3 glomerulopathy and immune-complex membranous proliferative glomerulonephritis using the United Kingdom RaDaR Registry. Kidney International. View this article in WRRO
- A role for class I p21-activated kinases in the regulation of the excitability of the actin cytoskeleton. Journal of Cell Science, 138(12). View this article in WRRO
- Balancing SHH and BMP/FGF10 to specify tuberal hypothalamic neurons and glia. Developmental Biology, 525, 259-269. View this article in WRRO
- ANKHD1 promotes pathogenic proliferation in Autosomal Dominant Polycystic Kidney Disease via the Cyclin D1/CDK4 pathway. Journal of Translational Medicine, 23. View this article in WRRO
- Circulating tumor DNA (ctDNA) in patients with muscle-invasive bladder cancer (MIBC) who received perioperative durvalumab (D) in NIAGARA.. Journal of Clinical Oncology, 43(16_suppl), 4503-4503.
- EPS7.09Verapamil limits inflammatory damage by reducing epithelial calcium activity in preclinical models of cystic fibrosis. Journal of Cystic Fibrosis, 24, S62-S62.
- Donor embryonic stem cells displace host cells of 8-cell stage chimeras to the extraembryonic lineages by spatial crowding and FGF4 signalling. Development, 152(12). View this article in WRRO
- Peto’s paradox’s relevance is off the scale. Aging, 17(6), 1371-1374. View this article in WRRO
- Modelling adrenal steroid profiles to inform monitoring guidance in congenital adrenal hyperplasia. eBioMedicine, 116, 105749-105749.
- ADP-ribosylation of NuMA promotes DNA single-strand break repair and transcription. Cell Reports, 44(6), 115737-115737.
- Subtypes and Sequencing in Bladder Cancer: Powering Personalised Treatment or Extraneous Information?. European Urology, 88(5), 482-483.
- A zebrafish model of acmsd deficiency does not support a prominent role for ACMSD in Parkinson’s disease. npj Parkinson's Disease, 11(1). View this article in WRRO
- PD37-09 THE FIRST REPORT OF DISEASE-FREE SURVIVAL ANALYSES FROM THE NIAGARA TRIAL OF PERIOPERATIVE DURVALUMAB PLUS NEOADJUVANT CHEMOTHERAPY IN MUSCLE-INVASIVE BLADDER CANCER. Journal of Urology, 213(5S).
- MP08-02 INVESTIGATING THE RELATIONSHIP BETWEEN CARDIOPULMONARY EXERCISE METRICS AND POST-OPERATIVE OUTCOMES IN RADICAL CYSTECTOMY: INSIGHTS FROM THE IROC PHASE 3 TRIAL. Journal of Urology, 213(5S).
- Replicating a COVID-19 study in a national England database to assess the generalisability of research with regional electronic health record data. BMJ Open, 15(4).
- Erratum: Randomized Comparison of Magnetic Resonance Imaging Versus Transurethral Resection for Staging New Bladder Cancers: Results From the Prospective BladderPath Trial. Journal of Clinical Oncology, 43(15), 1847-1847.
- Abstract 2600: A human stem cell model of neuroblastoma reveals candidate drivers of tumorigenesis on chromosome 17q. Cancer Research, 85(8_Supplement_1), 2600-2600.
- Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies. Communications Medicine, 5. View this article in WRRO
- Treatment selection and prioritization for the EJS ACT-PD MAMS trial platform. Movement Disorders, 40(7), 1307-1317. View this article in WRRO
- Improving the pathway to correct treatment for patients with muscle‐invasive bladder cancer: exploring the myths around the
BladderPath trial. BJU International, 136(1), 34-37.
- Incidence and prevalence of asthma, chronic obstructive pulmonary disease and interstitial lung disease between 2004 and 2023: harmonised analyses of longitudinal cohorts across England, Wales, South-East Scotland and Northern Ireland. Thorax, 80(7), 466-477.
- Blood pressure and its associations in 554 children and young people with CAH. European Journal of Endocrinology, 192(5), 529-539. View this article in WRRO
- Cost-effectiveness of de-escalated molecular subtype dependent use of neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer in a Swedish setting. Frontiers in Oncology, 15. View this article in WRRO
- No evidence for a trade-off between reproduction and survival in a meta-analysis across birds. eLife, 12. View this article in WRRO
- No evidence for a trade-off between reproduction and survival in a meta-analysis across birds. eLife.
- The Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheroma. The Lancet, 405(10486), 1264-1312. View this article in WRRO
- Curcumin-mediated NRF2 induction limits inflammatory damage in, preclinical models of cystic fibrosis. Biomedicine & Pharmacotherapy, 186. View this article in WRRO
- Local anaesthetic transperineal biopsy versus transrectal prostate biopsy in prostate cancer detection (TRANSLATE): a multicentre, randomised, controlled trial. The Lancet Oncology, 26(5), 583-595.
- Insights from ADPedKD, ERKReg and RaDaR registries provide a multi-national perspective on the presentation of childhood autosomal dominant polycystic kidney disease in high- and middle-income countries. Kidney International, 108(1), 105-118. View this article in WRRO
- Expansion of Drosophila haemocytes using a conditional GeneSwitch driver affects larval haemocyte function, but does not modulate adult lifespan or survival after severe infection. Journal of Experimental Biology, 228(9). View this article in WRRO
- Exploring stakeholder perspectives on the barriers and facilitators of implementing digital technologies for heart disease diagnosis: qualitative study. JMIR Cardio, 9. View this article in WRRO
- A0731 – Cardiopulmonary exercise testing and post-operative outcomes in radical cystectomy: Insights from the iROC phase 3 trial. European Urology, 87, S1567-S1567.
- A0086 – A randomised, double-blind phase II study of autogene cevumeran + nivolumab (nivo) vs. nivo as adjuvant therapy for patients with high-risk muscle-invasive urothelial carcinoma (MIUC). European Urology, 87, S885-S885.
- A0737 – Current status of the update of the EORTC health-related quality of life questionnaires for bladder cancer patients. European Urology, 87, S1574-S1574.
- Rare disease gene association discovery in the 100,000 Genomes Project. Nature. View this article in WRRO
- Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-κB pathways. Cardiovascular Research, 121(5), 748-759. View this article in WRRO
- A phase Ib window of opportunity study of atezolizumab administered intravesically or direct injection in patients undergoing radical cystectomy for bladder cancer: Results of the single dose cohorts.. Journal of Clinical Oncology, 43(5_suppl), 773-773.
- Additional efficacy and safety outcomes and an exploratory analysis of the impact of pathological complete response (pCR) on long-term outcomes from NIAGARA.. Journal of Clinical Oncology, 43(5_suppl), 659-659.
- Commentary: Tolvaptan for Autosomal Dominant Polycystic Kidney Disease (ADPKD) - an update. BMC Nephrology, 26(1). View this article in WRRO
- Protocol for a randomised phase 3 trial evaluating the role of Finasteride in active surveillance for men with low and intermediate-risk prostate cancer: the FINESSE study. BMJ Open, 15(2). View this article in WRRO
- Cerebrovascular ageing: how zebrafish can contribute to solving the puzzle. Frontiers in Physiology, 16. View this article in WRRO
- KDIGO 2025 clinical practice guideline for the evaluation, management, and treatment of autosomal dominant polycystic kidney disease (ADPKD): executive summary. Kidney International, 107(2), 234-254. View this article in WRRO
- KDIGO 2025 clinical practice guideline for the evaluation, management, and treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD). Kidney International, 107(2), S1-S239. View this article in WRRO
- morphoHeart: a quantitative tool for integrated 3D morphometric analyses of heart and ECM during embryonic development. PLOS Biology, 23(1). View this article in WRRO
- Development of TAR-200: A novel targeted releasing system designed to provide sustained delivery of gemcitabine for patients with bladder cancer. Urologic Oncology: Seminars and Original Investigations, 43(5), 286-296.
- The significance of isolated de novo red patches in the bladder in patients referred with suspected urinary tract cancer: results from the IDENTIFY study. BJUI Compass, 6(1). View this article in WRRO
- Home urine dipstick screening for bladder and kidney cancer in high-risk populations in England: a microsimulation study of long-term impact and cost-effectiveness. PharmacoEconomics, 43(4), 441-452. View this article in WRRO
- The Fat-Dachsous planar polarity pathway competes with hinge contraction to orient polarized cell behaviors during Drosophila wing morphogenesis. Current Biology, 35(2), 422-430.e3. View this article in WRRO
- Enhanced Recovery After Surgery for patients undergoing radical cystectomy: Surgeons’ perspectives and recommendations ten years after its implementation. European Journal of Surgical Oncology, 51(3), 109543-109543.
- Increasing Life Expectancy in Patients with Genitourinary Malignancies: Impact of Treatment Burden on Disease Management and Quality of Life. European Urology, 88(1), 11-20.
- Addressing the challenges of integrating digital health technologies to measure patient-centred outcomes in clinical registries. The Lancet Digital Health, 7(3), e225-e231.
- Heritability and age-dependent changes in genetic variation of telomere length in a wild house sparrow population. Evolution Letters, 9(2), 209-220. View this article in WRRO
- The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells. Developmental Cell, 60(3), 429-446.e6.
- FGFR Inhibition in Urothelial Carcinoma. European Urology, 87(2), 110-122.
- Real-word outcomes for high-risk non-muscle-invasive bladder cancer: screened patients for the BRAVO trial. BJU International, 135(2), 329-338. View this article in WRRO
- Control of tuberal hypothalamic development and its implications in metabolic disorders. Nature Reviews Endocrinology, 21(2), 118-130.
- Clinical spectrum and prognosis of atypical autosomal dominant polycystic kidney disease caused by monoallelic pathogenic variants of IFT140. American Journal of Kidney Diseases. View this article in WRRO
- Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation. Scientific Reports, 14(1). View this article in WRRO
- MT41 The Diagnostic Accuracy of Ultrasound and Genetic Tests for the Diagnosis of Autosomal Dominant Polycystic Kidney Disease: A Systematic Mapping Review. Value in Health, 27(12), S493-S493.
- Tetracycline and oxacillin act synergistically on biofilms and display increased efficacy in vivo against staphylococcus aureus. Current Microbiology, 81. View this article in WRRO
- A novel therapeutic pathway to the human cochlear nerve. Scientific Reports, 14. View this article in WRRO
- Insights into the human cDNA: A descriptive study using library screening in yeast. Journal of Genetic Engineering and Biotechnology, 22(4), 100427-100427.
- Parkinson’s families project: a UK-wide study of early onset and familial Parkinson’s disease. npj Parkinson's Disease, 10. View this article in WRRO
- 540P Assessing the effect of chronic nitrate supplementation on muscle mass and physical function outcomes. Neuromuscular Disorders, 43, 104441.131-104441.131.
- Peroxisomal import stress activates integrated stress response and inhibits ribosome biogenesis. PNAS Nexus, 3(10). View this article in WRRO
- Perioperative durvalumab with neoadjuvant chemotherapy in operable bladder cancer. New England Journal of Medicine, 391(19), 1773-1786. View this article in WRRO
- EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites Through Endothelial Fatty Acid Uptake. Circulation Research, 135(8), 822-837.
- LBA5 A randomized phase III trial of neoadjuvant durvalumab plus chemotherapy followed by radical cystectomy and adjuvant durvalumab in muscle-invasive bladder cancer (NIAGARA). Annals of Oncology, 35, S1271-S1271.
- Second generation lethality in RNAseH2a knockout zebrafish. Nucleic Acids Research, 52(18), 11014-11028. View this article in WRRO
- Pharmacological inhibition of ENT1 enhances the impact of specific dietary fats on energy metabolism gene expression. Proceedings of the National Academy of Sciences, 121(36). View this article in WRRO
- Mating proximity blinds threat perception. Nature, 634(8034), 635-643. View this article in WRRO
- COVID-19 diagnosis, vaccination during pregnancy, and adverse pregnancy outcomes of 865,654 women in England and Wales: a population-based cohort study. The Lancet Regional Health - Europe, 45, 101037-101037.
- Temporal trends in acute adrenal insufficiency events in children with congenital adrenal hyperplasia during 2019-2022. Journal of the Endocrine Society, 8(10). View this article in WRRO
- National audit of patient reported experience of radical cystectomy for bladder cancer pathways. BJUI Compass, 5(10), 1075-1082.
- Controversy in mechanotransduction: the role of endothelial cell-cell junctions in fluid shear stress sensing. Journal of Cell Science, 137(17). View this article in WRRO
- Genomic landscape of hepatocellular carcinoma in Egyptian patients by whole exome sequencing. BMC Medical Genomics, 17. View this article in WRRO
- Image directed redesign of bladder cancer treatment pathways: the BladderPath RCT. Health Technology Assessment, 28(42). View this article in WRRO
- Computational modelling of cardiovascular pathophysiology to risk stratify commercial spaceflight. Nature Reviews Cardiology, 21(10), 667-681.
- Exploring the role of E. faecalis enterococcal polysaccharide antigen (EPA) and lipoproteins in evasion of phagocytosis. Molecular Microbiology, 122(2), 230-242. View this article in WRRO
- Adult telomere length is positively correlated with survival and lifetime reproductive success in a wild passerine. Molecular Ecology, 33(15). View this article in WRRO
- Hypoxia‐responsive prodrug of ATR inhibitor, AZD6738, selectively eradicates treatment‐resistant cancer cells. Advanced Science, 11(34). View this article in WRRO
- A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts. The Lancet Digital Health, 6(7), e507-e519.
- Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle. Development, 151(13). View this article in WRRO
- Making cups and rings: the ‘stalled-wave’ model for macropinocytosis. Biochemical Society Transactions, 52(4), 1785-1794. View this article in WRRO
- Blood transfusion, radical cystectomy, and cancer recurrence: a new look at an old story. Comment on Ladner et al. Perioperative blood transfusion is associated with worse survival in patients undergoing radical cystectomy after neoadjuvant chemotherapy for muscle-invasive bladder cancer. Soc. Int. Urol. J. 2024, 5, 202–213. Société Internationale d’Urologie Journal, 5(3), 244-246. View this article in WRRO
- Tribbles1 is host protective during in vivo mycobacterial infection. eLife, 13. View this article in WRRO
- The DNA repair kinase ATM regulates CD13 expression and cell migration. Frontiers in Cell and Developmental Biology, 12. View this article in WRRO
- Sensory encoding and memory in the mushroom body: signals, noise, and variability. Learning & Memory, 31(5). View this article in WRRO
- WS16.04: When cystic fibrosis triggers a protective immunity against tuberculosis: loss of CFTR confers resistance to Mycobacterium marinum infections in cystic fibrosis zebrafish models. Journal of Cystic Fibrosis, 23(Supp 1), S30-S30. View this article in WRRO
- The psychosocial impact of prostate cancer screening for BRCA1 and BRCA2 carriers. BJU International, 134(3), 484-500. View this article in WRRO
- P207 The longitudinal assessment of anti-virulence gene expression in Pseudomonas aeruginosa grown in cystic fibrosis sputum mimics. Journal of Cystic Fibrosis, 23, S132-S133.
- Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue. Gut, 73(9), 1441-1453. View this article in WRRO
- Use of gene expression patterns to identify unique molecular subtypes in muscle invasive bladder cancer: GUSTO.. Journal of Clinical Oncology, 42(16_suppl), TPS4621-TPS4621.
- A comparative study of different antiviral treatment protocols in HCV related cryoglobulinemic vasculitis. Scientific Reports, 14(1). View this article in WRRO
- #2695 A Polycystin-1-Bicaudal C1 complex regulates focal adhesion function through integrin beta-1, F-actin organisation and local translation in HKE cells. Nephrology Dialysis Transplantation, 39(Supplement_1). View this article in WRRO
- Clinical spectrum and prognosis of the atypical polycystic kidney disease caused by monoallelic loss-of-function IFT140 variants. NEPHROLOGY DIALYSIS TRANSPLANTATION, 39, I213-I214.
- Polygenic risk scores validated in patient‐derived cells stratify for mitochondrial subtypes of Parkinson's disease. Annals of Neurology, 96(1), 133-149. View this article in WRRO
- Stakeholder perspectives on contributors to delayed and inaccurate diagnosis of cardiovascular disease and their implications for digital health technologies: a UK-based qualitative study. BMJ Open, 14. View this article in WRRO
- Macrophage transplantation rescues RNASET2-deficient leukodystrophy by replacing deficient microglia in a zebrafish model. Proceedings of the National Academy of Sciences, 121(21). View this article in WRRO
- Decision Regret Regarding Treatment Choices 1 Year After a New Diagnosis of Bladder Cancer. European Urology, 86(3), 286-288.
- Description and cross-sectional analyses of 25,880 adults and children in the UK National Registry of rare kidney diseases cohort. Kidney International Reports, 9(7), 2067-2083. View this article in WRRO
- A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations. Nature Communications, 15(1). View this article in WRRO
- PD36-04 REMOTE DIGITAL SURVEILLANCE AND MACHINE LEARNING MODELLING TO PREDICT SURVIVAL FOLLOWING RADICAL CYSTECTOMY FOR BLADDER CANCER—A SECONDARY OUTCOME ANALYSIS OF THE IROC TRIAL. Journal of Urology, 211(5S).
- Experimental evolution of Staphylococcus aureus in macrophages: dissection of a conditional adaptive trait promoting intracellular survival. mBio, 15(6). View this article in WRRO
- Relocating coincidence detection for associative learning.. J Physiol, 602(9), 1877-1878.
- Dietary restriction extends lifespan across different temperatures in the fly. Functional Ecology, 38(6), 1357-1363. View this article in WRRO
- Corrigendum to “An Artificial Intelligence Generated Automated Algorithm to Measure Total Kidney Volume in ADPKD” [Kidney International Reports Volume 9, Issue 2, February 2024, Pages 249-256]. Kidney International Reports.
- Aging-related defects in macrophage function are driven by MYC and USF1 transcriptional programs. Cell Reports, 43(4). View this article in WRRO
- Chronic kidney disease and the global public health agenda: an international consensus. Nature Reviews Nephrology, 20(7), 473-485. View this article in WRRO
- Clinical characteristics and kidney outcomes in Chinese patients with autosomal dominant polycystic kidney disease. Kidney360, 5(5), 715-723. View this article in WRRO
- The mechanical influence of densification on epithelial architecture. PLOS Computational Biology, 20(4). View this article in WRRO
- Service evaluation suggests variation in clinical care provision in adults with congenital adrenal hyperplasia in the UK and Ireland. Clinical Endocrinology, 101(4), 386-396. View this article in WRRO
- Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort. The Lancet, 403(10433), 1279-1289. View this article in WRRO
- What can we learn about fish neutrophil and macrophage response to immune challenge from studies in zebrafish. Fish & Shellfish Immunology, 148. View this article in WRRO
- Telomere length is an epigenetic trait – implications for the use of telomerase-deficient organisms to model human disease. Disease Models & Mechanisms, 17(3). View this article in WRRO
- Fabrication and characterisation of random and aligned electrospun scaffolds to investigate hypothalamic stem/progenitor cell behaviour. Engineered Regeneration, 5(1), 11-20.
- UPDATED EFFICACY AND SAFETY OF ORAL ERDAFITINIB IN PATIENTS WITH BACILLUS CALMETTE-GUÉRIN–UNRESPONSIVE, HIGH-RISK NON-MUSCLE–INVASIVE BLADDER CANCER WITH FGFR3/2 ALTERATIONS IN THOR-2 COHORT 2. Urologic Oncology: Seminars and Original Investigations, 42, S53-S53.
- Digital remote monitoring and Machine Learning (ML) modeling to predict survival following radical cystectomy for bladder cancer – a secondary outcome analysis of the iROC trial. European Urology, 85, S929-S930.
- SunRISe-3: TAR-200 plus cetrelimab or TAR-200 versus intravesical Bacillus Calmette–Guérin in patients with BCG-naive high-risk non–muscle-invasive bladder cancer. European Urology, 85, S1505-S1505.
- Clinical Application of Bladder MRI and Vesical Imaging-Reporting And Data System. European Urology, 85, S1874-S1875.
- ASXL3‐related disorder: molecular phenotyping and comprehensive review providing insights into disease mechanism. Clinical Genetics, 105(5), 470-487. View this article in WRRO
- Gene of the month: the uroplakins. Journal of Clinical Pathology, 77(5), 291-296.
- Global analysis of urinary extracellular vesicle small RNAs in autosomal dominant polycystic kidney disease. The Journal of Gene Medicine, 26(2). View this article in WRRO
- HYDROchlorothiazide versus placebo to PROTECT polycystic kidney disease patients and improve their quality of life: study protocol and rationale for the HYDRO-PROTECT randomized controlled trial. Trials, 25(1). View this article in WRRO
- Improved Disease-Free Survival With Adjuvant Chemotherapy After Nephroureterectomy for Upper Tract Urothelial Cancer: Final Results of the POUT Trial. Journal of Clinical Oncology, 42(13), 1466-1471.
- The people behind the papers – Fay Cooper and Anestis Tsakiridis. Development, 151(3).
- Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors. Development, 151(3). View this article in WRRO
- Verification of molecular subtyping of bladder cancer in the GUSTO clinical trial. The Journal of Pathology: Clinical Research, 10(2). View this article in WRRO
- Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Nature Communications, 15. View this article in WRRO
- Correction to “A
p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo”. Aging Cell, 23(3).
- INVEST: A phase Ib window of opportunity study of atezolizumab administered either intravesically or direct tumour injection in patients with bladder cancer prior to radical cystectomy.. Journal of Clinical Oncology, 42(4_suppl), TPS710-TPS710.
- Thromboembolic events associated with neoadjuvant chemotherapy for muscle invasive cancer of the bladder.. Journal of Clinical Oncology, 42(4_suppl), 586-586.
- Real world outcomes for maintenance avelumab treatment in locally advanced/metastatic urothelial cancer after platinum-based chemotherapy.. Journal of Clinical Oncology, 42(4_suppl), 584-584.
- A National Survey of Paediatric Turner Syndrome Services in the United Kingdom: Current Practice and Variability in Care. Hormone Research in Paediatrics, 1-11.
- Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England. Frontline Gastroenterology.
- Resolving forebrain developmental organisation by analysis of differential growth patterns. Nature Communications.
- Twelve-Month Results From the CISTO Study Comparing Radical Cystectomy Versus Bladder-Sparing Therapy for Recurrent High-Grade Non–Muscle-Invasive Bladder Cancer. Journal of Clinical Oncology.
- Author Correction: Evidence for improved DNA repair in the long-lived bowhead whale. Nature.
- EndoCompass Project: Research Roadmap for Adrenal and Cardiovascular Endocrinology. Hormone Research in Paediatrics, 1-13.
- Separating the genetic and environmental drivers of body temperature during the development of endothermy in an altricial bird. Journal of Evolutionary Biology.
- TGF-beta coordinates changes in Keratin gene expression during complex tissue regeneration. Scientific Reports, 15(1).
- Candida albicans
Cells Lacking
AP ‐2 Have Defective Hyphae and Are Avirulent Despite Increased Host Uptake and Intracellular Proliferation in Macrophages. Molecular Microbiology.
- A national survey of paediatric turner syndrome services in the united kingdom: current practice and variability in care. Endocrine Abstracts.
- Pilot data from the I-HH registry: improving management in hypogonadotropic hypogonadism. Endocrine Abstracts.
- Genetic Testing in Autosomal Dominant Polycystic Kidney Disease: Why It Matters in 2025. Clinical Kidney Journal.
- Telomerase Depletion Accelerates Ageing of the Zebrafish Brain. Aging Cell.
- Surgical familiarity: many questions but the benefits are clear. BJU International.
- The Current Treatment Landscape for Congenital Adrenal Hyperplasia. Drugs.
- Bridging Physics and Aging Biology: Insights from the First Physics in Aging Biology Workshop. Aging Biology, 3(1), 20250042-20250042.
- Diagnostic work-up of paediatric adrenocortical tumours - International consensus through a modified Delphi process. Endocrine Abstracts.
- Exploring the role of glucocorticoids and androgens in the regulation of brain immunity using zebrafish models of impaired steroidogenesis. Endocrine Abstracts.
- Thematic analysis of quality of life in a community-based sample of adults living with congenital adrenal hyperplasia reveals a significant unmet medical need. Endocrine Abstracts.
- Randomized Comparison of Magnetic Resonance Imaging Versus Transurethral Resection for Staging New Bladder Cancers: Results From the Prospective BladderPath Trial. Journal of Clinical Oncology.
- Understanding the long‐term impact of the COVID‐19 pandemic on non‐muscle‐invasive bladder cancer outcomes: 12‐Month follow‐up data from the international, prospective COVIDSurg Cancer study. BJUI Compass.
- National Service Evaluation of the Quality of Care for Children and Young People with Congenital Adrenal Hyperplasia in the UK: Survey Responses from Patients and Clinicians. Hormone Research in Paediatrics, 98(3), 296-306.
Book chapters
- Development of the semicircular canals and otolithic organs of the vertebrate inner ear In Richardson GP & Wu DK (Ed.), Development of Sensory Organs (pp. 125-184). Elsevier View this article in WRRO
- Drosophila as a Model for Metastasis, Advances in Experimental Medicine and Biology (pp. 135-154). Springer Nature Switzerland
- Light-Sheet Microscopy Enables Three-Dimensional Fluorescence Imaging and Live Imaging of Satellite Cells on Skeletal Muscle Fibers, Methods in Molecular Biology (pp. 89-101). Springer US
- Adult zebrafish as a vertebrate model of ageing, Zebrafish (pp. 159-181). CABI
Conference proceedings
- 178 EJS ACT-PD: launching a multi-arm multi-stage platform trial for potential disease-modifying approaches in parkinsons disease. 178 EJS ACT-PD: launching a multi-arm multi-stage platform trial for potential disease-modifying approaches in parkinsons disease (pp A55.1-A55)
- Body Size and Non-Muscle Invasive Bladder Cancer Outcome: What Do the Genes Say?. GENETIC EPIDEMIOLOGY, Vol. 49(7)
- In-depth characterization of the colonic pathology of the B6;129-Ednrbtm1Ywa/J mouse model of Hirschsprung disease and stem cell-based rescue. NEUROGASTROENTEROLOGY AND MOTILITY, Vol. 37
- The diagnostic accuracy of ultrasound and genomic tests for the diagnosis of autosomal-dominant polycystic kidney disease: a systematic mapping review. Clinical Kidney Journal, Vol. 18(7) View this article in WRRO
- 6 Assessing the role of PET-CT in diagnosing cardiac sarcoid: a retrospective review of referral pathways and diagnostic outcomes in a newly established tertiary centre service. BSCI BSCCT Abstracts Conference 2–4 April (pp A2.3-A2)
- A randomised, double-blind phase II study of autogene cevumeran plus nivolumab (nivo) vs. nivo as adjuvant therapy for patients with high-risk muscle-invasive urothelial carcinoma (MIUC). EUROPEAN UROLOGY, Vol. 87
- Current status of the update of the EORTC health-related quality of life questionnaires for bladder cancer patients. EUROPEAN UROLOGY, Vol. 87
- Cost-effectiveness of de-escalated molecular subtype dependent use of neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer. EUROPEAN UROLOGY, Vol. 87
- Cardiopulmonary exercise testing and post-operative outcomes in radical cystectomy: Insights from the iROC phase 3 trial. EUROPEAN UROLOGY, Vol. 87
- Lessons from CAH service evaluation and real-world data. HORMONE RESEARCH IN PAEDIATRICS, Vol. 97 (pp 15-16)
- Real world data analysis of contemporary therapy and its association to anthropometric outcomes in 1500 patients with congenital adrenal hyperplasia (CAH). HORMONE RESEARCH IN PAEDIATRICS, Vol. 97 (pp 43-44)
- Non-invasive biochemical monitoring for Congenital Adrenal Hyperplasia: use of urinary steroid metabolites and salivary 17α-Hydroxyprogesterone. HORMONE RESEARCH IN PAEDIATRICS, Vol. 97 (pp 209-210)
- Variation in Blood Pressure in Young Adults with 21a-Hydroxylase Deficiency: Longitudinal Multilevel Modelling of Data from the I-CAH Registry. HORMONE RESEARCH IN PAEDIATRICS, Vol. 97 (pp 154-155)
- I026 Screening for mitochondrial therapeutics in Huntington’s disease using patient-derived cells. I: Experimental therapeutics – preclinical (pp A152.1-A152)
- Pubertal induction in girls with turner syndrome: updated retrospective data from the international TS registry. Endocrine Abstracts
Posters
- SAT-420 First insights into the health status of adults with CAH in the UK and Ireland - CaHASE2. ENDO 2025 Annual Meeting of the Endocrine Society. View this article in WRRO
Preprints
- During an inflammatory response, zebrafish
tnfa
and
tnfb
are expressed by different cell types and have distinct expression kinetics, Cold Spring Harbor Laboratory.
- Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England, Cold Spring Harbor Laboratory.
- BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD, eLife Sciences Publications, Ltd.
- BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD, eLife Sciences Publications, Ltd.
- Functional and molecular rescue of aganglionic colon by human enteric nervous system progenitor transplantation in Hirschsprung disease, Cold Spring Harbor Laboratory.
- Verapamil limits inflammation by restoring VGCC-driven epithelial Ca2+ in models of cystic fibrosis, Cold Spring Harbor Laboratory.
- Beyond pulling: microtubule pushing forces contribute to robust spindle orientation in regular and irregular cell shapes, Cold Spring Harbor Laboratory.
- Secondary nucleation of α-Synuclein drives Mitochondria dysfunctions and Lewy body formation in Parkinson’s Disease, Springer Science and Business Media LLC.
- The evolution of asymmetrical regulation of physiology is central to aging, arXiv.
- Secondary nucleation of α-Synuclein drives Mitochondria dysfunctions and Lewy body formation in Parkinson’s Disease, Cold Spring Harbor Laboratory.
- Suppression rather than activation of the integrated-stress-response (GCN2-ATF4) pathway extends lifespan in the fly, Cold Spring Harbor Laboratory.
- Open Benchmarking for Cell-Based Multiscale Models: Lessons from a Community Initiative, Cold Spring Harbor Laboratory.
- Type I interferon responses contribute to immune protection against mycobacterial infection, eLife Sciences Publications, Ltd.
- Type I interferon responses contribute to immune protection against mycobacterial infection, eLife Sciences Publications, Ltd.
- TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques, Cold Spring Harbor Laboratory.
- Polycystin-1 acts as an atypical adhesion GPCR that responds to novel Wnt signaling and mechanical stimuli, Cold Spring Harbor Laboratory.
- Telomerase reverse transcriptase is required for resistance to mycobacterial infection, Cold Spring Harbor Laboratory.
- Examining the genetic and phenotypic correlation between survival and fecundity in a wild bird, Cold Spring Harbor Laboratory.
- Artificial Intelligence Remote Patient Monitoring (AI RPM) for predicting overall survival for patients undergoing radical cystectomy for bladder cancer: an exploratory analysis of the prospective trial iROC (Preprint), JMIR Publications Inc..
- Dietary restriction is evolutionary conserved on the phenotypic and mechanistic level, Cold Spring Harbor Laboratory.
- Mechanical fracturing of the extracellular matrix patterns the vertebrate heart, Cold Spring Harbor Laboratory.
- The optimal clutch size revisited: separating individual quality from the parental survival costs of reproduction, eLife Sciences Publications, Ltd.
- Loneliness, Social Isolation, and Effects on Cognitive Decline in Patients with Dementia: A Retrospective Cohort Study Using Natural Language Processing, Cold Spring Harbor Laboratory.
- Endoplasmic Reticulum Stress Impairs Macrophage Efferocytosis via TRIB3-Rab27a Signaling and Exacerbates Atherosclerotic Plaque Necrosis, Springer Science and Business Media LLC.
- Resolving forebrain developmental organisation by analysis of differential growth patterns, Cold Spring Harbor Laboratory.
- Donor embryonic stem cells impede host epiblast specification in 8-cell stage chimeras by crowding and FGF4 signalling, Cold Spring Harbor Laboratory.
- Paired and solitary ionocytes in the zebrafish olfactory epithelium, Cold Spring Harbor Laboratory.
- A role for class I PAKs in the regulation of the excitability of the actin cytoskeleton, Cold Spring Harbor Laboratory.
- The optimal clutch size revisited: separating individual quality from the parental survival costs of reproduction, eLife Sciences Publications, Ltd.
- Expansion ofDrosophilahaemocytes using a conditionalGeneSwitchdriver affects larval haemocyte function, but does not modulate adult lifespan or survival from infection, Cold Spring Harbor Laboratory.
- Exploring Stakeholder Perspectives on the Barriers and Facilitators of Implementing Digital Technologies for Heart Disease Diagnosis: Qualitative Study (Preprint), JMIR Publications Inc..
- BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD, Cold Spring Harbor Laboratory.
- Separating the genetic and environmental drivers of body temperature during the development of endothermy in an altricial bird, Cold Spring Harbor Laboratory.
- Type I interferon responses contribute to immune protection against mycobacterial infection, Cold Spring Harbor Laboratory.
- Exploring the role ofE. faecalisEnterococcal Polysaccharide Antigen (EPA) and lipoproteins in evasion of phagocytosis, Cold Spring Harbor Laboratory.
- The optimal clutch size revisited: separating individual quality from the parental survival costs of reproduction, eLife Sciences Publications, Ltd.
- Exploring the role of E. faecalis Enterococcal Polysaccharide Antigen (EPA) and lipoproteins in evasion of phagocytosis, Wiley.
- Biallelic mutations in SUPV3L1 cause an inherited neurodevelopmental disorder with variable leukodystrophy due to aberrant mitochondrial double stranded RNA processing, Springer Science and Business Media LLC.
- Mating proximity blinds threat perception., Cold Spring Harbor Laboratory.
- Curcumin-mediated NRF2 induction limits inflammatory damage in preclinical models of cystic fibrosis, Cold Spring Harbor Laboratory.
- Pulses of Class I PI3kinase activity identify the release and recapture of prey from neutrophil phagosomes, Cold Spring Harbor Laboratory.
- Senataxin modulates resistance to cisplatin through an R-loop mediated mechanism in HPV-associated Head and Neck Squamous Cell Carcinoma, Cold Spring Harbor Laboratory.
- Sleep Facilitates Pattern Separation through SK Channel-Mediated Sparse Coding, bioRxiv.