Brian Rice
BSc (Hons), MSc, PhD
Population Health, School of Medicine and Population Health
Senior Lecturer
- Profile
-
I am an Epidemiologist with an interest in maximising the strategic potential of health data collected through surveillance and service delivery platforms. I have developed methods that strengthen the infrastructure of national, regional, and global-level public health surveillance platforms.
To maximise the use of data provided by these platforms, I have developed new methods for data linkage, quality improvement, and visualisation, as well as designed new indicators and implemented novel methods to monitor and improve programme performance. I sit on a number of global working and advisory groups, including the UNAIDS Monitoring Technical Advisory Group (to which I have contributed since 2007, and for which I was the inaugural co-chair).
I took up my position at the University of Sheffield in April 2023. I am the Impact lead for ScHARR and Global Health theme lead. I have previously worked at the Communicable Disease Surveillance Centre, the Health Protection Agency, the African Health Research Institute, Public Health England, and the London School of Hygiene and Tropical Medicine (LHSTM).
At LSHTM, I was the director of the Measurement & Surveillance of HIV Epidemics (MeSH) consortium, and co-director of the cross-faculty Centre for Evaluation and the Sustainable Development Goal Health & Wellbeing Research (SDG-HaW) consortium. I retain an honorary position as Associate Professor at LSHTM.
- Qualifications
-
PhD Health Sciences, City University London (2016)
MSc Environmental Epidemiology & Policy, London School of Hygiene and Tropical Medicine (2001)
- Research interests
-
My primary research interest is strengthening the collection, collation, and use of HIV data to inform prevention and care programming in sub-Saharan Africa.
Working towards this broad objective, my key research areas are
- developing epidemiological methods to strengthen the collection and use of data collected through surveillance and service delivery platforms
- characterising the locations, populations and individuals at greatest risk of infectious disease
- designing and implementing frameworks to collect strategic health data
- constructing health indicators / minimum indicator-sets
- implementing continuous data quality improvement
- formative research into the health and wellbeing needs and priorities of communities
- Publications
-
Journal articles
- Effect of a multicomponent, person-centred care intervention on client experience and HIV treatment outcomes in Zambia: a stepped-wedge, cluster-randomised trial. The Lancet HIV.
- Recent infection testing to inform HIV prevention responses and surveillance in a programme context: lessons from implementation within a nationally scaled female sex worker programme in Zimbabwe. Journal of the International AIDS Society, 27(12).
- Interventions to ensure access to and continuity of HIV care for international migrants: an evidence synthesis. The Lancet HIV.
- Population size, HIV prevalence, and antiretroviral therapy coverage among key populations in sub-Saharan Africa: collation and synthesis of survey data, 2010–23. The Lancet Global Health, 12(9), e1400-e1412.
- Characterising HIV acquisition risk, treatment gaps and populations reached through venue-based outreach and clinical services in Blantyre, Malawi: findings from a district-wide CLOVE Study. JAIDS Journal of Acquired Immune Deficiency Syndromes.
- HIV incidence among women engaging in sex work in sub-Saharan Africa: a systematic review and meta-analysis. The Lancet Global Health, 12(8), e1244-e1260. View this article in WRRO
- Moving towards a person-centred HIV care cascade: An exploration of potential biases and errors in routine data in South Africa. PLOS Global Public Health, 4(6), e0002509-e0002509.
- Comparison of Empirically Derived and Model-Based Estimates of Key Population HIV Incidence and the Distribution of New Infections by Population Group in Sub-Saharan Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 95(1S), e46-e58.
- “Sex without fear”: exploring the psychosocial impact of oral HIV pre-exposure prophylaxis on gay men in England. AIDS Research and Therapy, 20(1), 81.
- Comparison of patient exit interviews with unannounced standardised patients for assessing HIV service delivery in Zambia: a study nested within a cluster randomised trial. BMJ Open, 13(7), e069086-e069086.
- Temporal trends in, and risk factors for, HIV seroconversion among female sex workers accessing Zimbabwe's national sex worker programme, 2009–19: a retrospective cohort analysis of routinely collected HIV testing data. The Lancet HIV, 10(7), e442-e452.
- Brief Report: Adolescent Girls Who Sell Sex in Zimbabwe: HIV Risk, Behaviours, and Service Engagement. JAIDS Journal of Acquired Immune Deficiency Syndromes, 90(3), 263-269.
- Interpreting declines in HIV test positivity: an analysis of routine data from Zimbabwe's national sex work programme, 2009–2019. Journal of the International AIDS Society, 25(7).
- Estimation of HIV incidence from analysis of HIV prevalence patterns among female sex workers in Zimbabwe. AIDS, 36(8), 1141-1150.
- Health and wellbeing needs and priorities in mining host communities in South Africa: a mixed-methods approach for identifying key SDG3 targets. BMC Public Health, 22(1).
- Patterns of engagement in HIV care during pregnancy and breastfeeding: findings from a cohort study in North-Eastern South Africa. BMC Public Health, 21(1).
- Post-migration acquisition of HIV: Estimates from four European countries, 2007 to 2016. Eurosurveillance, 26(33).
- The HIV care cascade in sub‐Saharan Africa: systematic review of published criteria and definitions. Journal of the International AIDS Society, 24(7).
- Experiences and lessons learned from the real-world implementation of an HIV recent infection testing algorithm in three routine service-delivery settings in Kenya and Zimbabwe. BMC Health Services Research, 21(1).
- Influence of evolving HIV treatment guidance on CD4 counts and viral load monitoring: A mixed-methods study in three African countries. Global Public Health, 16(2), 288-304.
- High variability in the measurement of HIV primary prevention activities and outcomes. Journal of the International AIDS Society, 23(12).
- The impact of HIV status on the distance traveled to health facilities and adherence to care. A record-linkage study from rural South Africa. Journal of Global Health, 10(2).
- Consolidating strategic information to monitor progress against the UNAIDS 90–90–90 targets: evaluating the operational feasibility of an electronic HIV testing register in Cape Town, South Africa. BMC Health Services Research, 20(1).
- Can HIV recent infection surveillance help us better understand where primary prevention efforts should be targeted? Results of three pilots integrating a recent infection testing algorithm into routine programme activities in Kenya and Zimbabwe. Journal of the International AIDS Society, 23(S3).
- Outcomes After Being Lost to Follow-up Differ for Pregnant and Postpartum Women When Compared With the General HIV Treatment Population in Rural South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 85(2), 127-137.
- Estimating the Population Size of Female Sex Workers in Zimbabwe: Comparison of Estimates Obtained Using Different Methods in Twenty Sites and Development of a National-Level Estimate. JAIDS Journal of Acquired Immune Deficiency Syndromes, 85(1), 30-38.
- Brief Report: Recent HIV Infection Surveillance in Routine HIV Testing in Nairobi, Kenya: A Feasibility Study. JAIDS Journal of Acquired Immune Deficiency Syndromes, 84(1), 5-9.
- Repositioning Implementation Science in the HIV Response: Looking Ahead From AIDS 2018. JAIDS Journal of Acquired Immune Deficiency Syndromes, 82(3), S299-S304.
- Chemsex is not a barrier to self-reported daily PrEP adherence among PROUD study participants. International Journal of Drug Policy, 74, 246-254.
- Outcomes of patients lost to follow‐up after antiretroviral therapy initiation in rural north‐eastern South Africa. Tropical Medicine & International Health, 24(6), 747-756.
- Changes in patterns of retention in HIV care and antiretroviral treatment in Tanzania between 2008 and 2016: an analysis of routinely collected national programme data. Journal of Global Health, 9(1).
- How Can Programs Better Support Female Sex Workers to Avoid HIV Infection in Zimbabwe? A Prevention Cascade Analysis. JAIDS Journal of Acquired Immune Deficiency Syndromes, 81(1), 24-35.
- Non-disclosure of HIV testing history in population-based surveys: implications for estimating a UNAIDS 90-90-90 target. Global Health Action, 11(1), 1553470-1553470.
- Outcomes of Patients Lost to Follow-up in African Antiretroviral Therapy Programs: Individual Patient Data Meta-analysis. Clinical Infectious Diseases, 67(11), 1643-1652.
- Monitoring the HIV continuum of care in key populations across Europe and Central Asia. HIV Medicine, 19(7), 431-439.
- The HIV Care Cascade from HIV diagnosis to viral suppression in sub-Saharan Africa: a systematic review and meta-regression analysis protocol. Systematic Reviews, 6(1).
- HIV continuum of care in Europe and Central Asia. HIV Medicine, 18(7), 490-499.
- Monitoring of the HIV Epidemic Using Routinely Collected Data: The Case of the United Kingdom. AIDS and Behavior, 21(S1), 83-90.
- Quality assurance and quality improvement in national HIV prevention policies in Europe. European Journal of Public Health, 25(suppl_3).
- CD4+ cell count responses to antiretroviral therapy are not impaired in HIV-infected individuals with tuberculosis co-infection. AIDS, 29(11), 1363-1368.
- A systematic review of post-migration acquisition of HIV among migrants from countries with generalised HIV epidemics living in Europe: mplications for effectively managing HIV prevention programmes and policy. BMC Public Health, 15(1).
- Does antiretroviral therapy reduce HIV-associated tuberculosis incidence to background rates? A national observational cohort study from England, Wales, and Northern Ireland. The Lancet HIV, 2(6), e243-e251.
- Impact of TB on the survival of people living with HIV infection in England, Wales and Northern Ireland. Thorax, 70(6), 566-573.
- Sharp truth: health care workers remain at risk of bloodborne infection. Occupational Medicine, 65(3), 210-214.
- Bloodborne viruses and workplace injury risk. Nursing Times, 111(8), 12-14.
- Universal treatment success among healthcare workers diagnosed with occupationally acquired acute hepatitis C. Journal of Hospital Infection, 89(1), 69-71.
- P1288 HEALTHCARE WORKERS CONTINUE TO BE AT RISK OF OCCUPATIONAL EXPOSURES TO BLOODBORNE VIRUSES IN THE UK. Journal of Hepatology, 60(1), S519-S519.
- Trends in HIV Diagnoses, HIV Care, and Uptake of Antiretroviral Therapy Among Heterosexual Adults in England, Wales, and Northern Ireland. Sexually Transmitted Diseases, 41(4), 257-265.
- S58 TB co-infection is associated with poor survival among HIV infected patients in england and wales. Thorax, 68(Suppl 3), A32.1-A32.
- Ten-year mortality trends among persons diagnosed with HIV infection in England and Wales in the era of antiretroviral therapy: AIDS remains a silent killer. HIV Medicine, 14(10), 596-604.
- Early diagnosis and treatment of HIV infection: magnitude of benefit on short-term mortality is greatest in older adults. Age and Ageing, 42(4), 520-526.
- Decreasing incidence of tuberculosis among heterosexuals living with diagnosed HIV in England and Wales. AIDS, 27(7), 1151-1157.
- HIV incidence in men who have sex with men in England and Wales 2001–10: a nationwide population study. The Lancet Infectious Diseases, 13(4), 313-318.
- HIV testing in black Africans living in England. Epidemiology and Infection, 141(8), 1741-1748.
- A new method to assign country of HIV infection among heterosexuals born abroad and diagnosed with HIV. AIDS, 26(15), 1961-1966.
- Safe travels? HIV transmission among Britons travelling abroad. HIV Medicine, 13(5), 315-317.
- Invasive pneumococcal disease among HIV-positive individuals, 2000–2009. AIDS, 26(1), 87-94.
- Loss to Follow-Up Among Adults Attending Human Immunodeficiency Virus Services in England, Wales, and Northern Ireland. Sexually Transmitted Diseases, 38(8), 685-690.
- Tuberculosis and HIV co-infection in European Union and European Economic Area countries. European Respiratory Journal, 38(6), 1382-1392.
- The burden of TB-HIV in the EU: how much do we know? A survey of surveillance practices and results. European Respiratory Journal, 38(6), 1374-1381.
- Increasing HIV infection among adults aged 50 years and over: a call for heightened awareness. Therapy, 8(2), 201-205.
- Travel for HIV care in England: a choice or a necessity?. HIV Medicine, 12(6), 361-366.
- Insights into the rise in HIV infections, 2001 to 2008: a Bayesian synthesis of prevalence evidence. AIDS, 24(18), 2849-2858.
- P170 TB-HIV co-infection: how does the UK compare to Europe?. Thorax, 65(Suppl 4), A150-A150.
- HIV type-1 drug resistance in antiretroviral treatment-naive adults infected with non-B subtype virus in the United Kingdom. Antiviral Therapy, 15(7), 985-991.
- HIV transmission and high rates of late diagnoses among adults aged 50 years and over. AIDS, 24(13), 2109-2115.
- HIV infection and suicide in the era of HAART in England, Wales and Northern Ireland. AIDS, 24(11), 1795-1797.
- Trends over calendar time in antiretroviral treatment success and failure in HIV clinic populations. HIV Medicine.
- The impact in the UK of the Central and Eastern European HIV epidemics. Epidemiology and Infection, 137(9), 1266-1271.
- Vertically acquired HIV diagnosed in adolescence and early adulthood in the United Kingdom and Ireland: findings from national surveillance. HIV Medicine, 10(4), 253-256.
- Situation of HIV infections and STIs in the United Kingdom in 2007. Eurosurveillance, 13(49).
- Could male circumcision reduce HIV incidence in the UK?. HIV Medicine, 9(6), 329-331.
- Continuing high levels of HIV diagnoses in men who have sex with men in the United Kingdom. Eurosurveillance, 13(14), 3-4.
- Population and antenatal-based HIV prevalence estimates in a high contracepting female population in rural South Africa. BMC Public Health, 7(1).
- The changing epidemiology of diagnosed prevalent HIV infections in England: greatest impact on the London environs. Epidemiology and Infection, 135(1), 151-158.
- Monitoring the effectiveness of HIV and STI prevention initiatives in England, Wales, and Northern Ireland: where are we now?. Sexually Transmitted Infections, 82(1), 4-10.
- Epidemiology of HIV among black and minority ethnic men who have sex with men in England and Wales. Sexually Transmitted Infections, 81(4), 345-350.
- The changing epidemiology of prevalent diagnosed HIV infections in England, Wales, and Northern Ireland, 1997 to 2003. Sexually Transmitted Infections, 81(3), 223-229.
- No time to wait: how many HIV-infected homosexual men are diagnosed late and consequently die? (England and Wales, 1993–2002). AIDS, 19(5), 513-520.
- Recent trends in diagnoses of HIV and other sexually transmitted infections in England and Wales among men who have sex with men. Sexually Transmitted Infections, 80(6), 492-497.
- Prevalent diagnosed HIV in England, Wales and Northern Ireland. AIDS, 18(6), 927-932.
- Promising results of HIV prevention trials highlight the benefits of collaboration in global health: The perspective of the Forum HIV Recency Assay Working Group. PLOS Global Public Health, 4(10), e0003878-e0003878.
- Use of routinely collected blood donation data for expanded HIV and Syphilis surveillance in Blantyre district, Malawi. PLOS ONE, 19(8), e0300647-e0300647.
- The cyclical cascade of HIV care: Temporal care engagement trends within a population-wide cohort. PLOS Medicine, 21(5), e1004407-e1004407.
- Can routine antenatal data be used to assess HIV antiretroviral therapy coverage among pregnant women? Evaluating the validity of different data sources in the Western Cape, South Africa. PLOS ONE, 19(4), e0291844-e0291844.
- Establishing the health and wellbeing needs of mining host community in Brazil, Chile and Peru: a mixed-method approach to identify priority areas for action to help communities meet their SDG3 targets. BMC Public Health, 23(1).
- Comparison of programmatic data from antenatal clinics with population-based HIV prevalence estimates in the era of universal test and treat in western Kenya. PLOS ONE, 18(6), e0287626-e0287626.
- Facilitating Next‐Generation Pre‐Exposure Prophylaxis Clinical Trials Using
HIV Recent Infection Assays: A Consensus Statement from the ForumHIV Prevention Trial Design Project. Clinical Pharmacology & Therapeutics. - The validity of routine individuated programmatic data in HIV surveillance assessed over a 10-year period.. International Journal of Population Data Science, 7(3).
- Investigating clinic transfers among HIV patients considered lost to follow-up to improve understanding of the HIV care cascade: Findings from a cohort study in rural north-eastern South Africa. PLOS Global Public Health, 2(5), e0000296-e0000296.
- The revolving door of HIV care: Revising the service delivery cascade to achieve the UNAIDS 95-95-95 goals. PLOS Medicine, 18(5), e1003651-e1003651.
- Utility of digitising point of care HIV test results to accurately measure, and improve performance towards, the UNAIDS 90-90-90 targets. PLOS ONE, 15(6), e0235471-e0235471.
- Misreporting of Patient Outcomes in the South African National HIV Treatment Database: Consequences for Programme Planning, Monitoring, and Evaluation. Frontiers in Public Health, 8.
- Characterizing a Leak in the HIV Care Cascade: Assessing Linkage Between HIV Testing and Care in Tanzania. Frontiers in Public Health, 7.
- Challenges to the performance of current HIV diagnostic assays and the need for centralized specimen archives: a review of the Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA) repository. Gates Open Research, 3, 1511-1511.
- The Continuing Value of CD4 Cell Count Monitoring for Differential HIV Care and Surveillance. JMIR Public Health and Surveillance, 5(1), e11136-e11136.
- Pluripotency of Wolbachia against Arbovirus: the case of yellow fever. Gates Open Research, 3, 161-161.
- The association between being currently in school and HIV prevalence among young women in nine eastern and southern African countries. PLOS ONE, 13(6), e0198898-e0198898.
- Strengthening Routine Data Systems to Track the HIV Epidemic and Guide the Response in Sub-Saharan Africa. JMIR Public Health and Surveillance, 4(2), e36-e36.
- Know Your Epidemic, Strengthen Your Response: Developing a New HIV Surveillance Architecture to Guide HIV Resource Allocation and Target Decisions. JMIR Public Health and Surveillance, 4(1), e18-e18.
- Authorship Correction: Sampling Key Populations for HIV Surveillance: Results From Eight Cross-Sectional Studies Using Respondent-Driven Sampling and Venue-Based Snowball Sampling. JMIR Public Health and Surveillance, 4(1), e9-e9.
- Sampling Key Populations for HIV Surveillance: Results From Eight Cross-Sectional Studies Using Respondent-Driven Sampling and Venue-Based Snowball Sampling. JMIR Public Health and Surveillance, 3(4), e72-e72.
- Feasibility of Establishing HIV Case-Based Surveillance to Measure Progress Along the Health Sector Cascade: Situational Assessments in Tanzania, South Africa, and Kenya. JMIR Public Health and Surveillance, 3(3), e44-e44.
Chapters
- Chapter 5: Harnessing the strength of routine data for HIV surveillance In Dalal S (Ed.), CONSOLIDATED GUIDELINES ON PERSON-CENTRED HIV STRATEGIC INFORMATION - STRENGTHENING ROUTINE DATA FOR IMPACT Geneva, Switzerland: World Health Organization.
Conference proceedings papers
- Trends in HIV testing yield need to be interpreted within the context of changing testing patterns: analysis of individual-level programme data from Zimbabwe's national sex work programme, 2009 to 2019. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, Vol. 24 (pp 56-56)
- Apples and oranges: Assessment of the care cascade in sub-Saharan Africa. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, Vol. 22 (pp 69-70)
- How can programmes better support female sex workers to avoid HIV infection in Zimbabwe? A prevention cascade analysis. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, Vol. 21 (pp 81-81)
Preprints
- What’s in a name? Consistent definitions of key populations and risk factors could enhance routine HIV surveillance, F1000 Research Ltd.
- Comparing the test performance of dried-blood-spot and plasma HIV recent infection testing samples in a nationally scaled sex worker programme in Zimbabwe, Cold Spring Harbor Laboratory.
- Exploring the validity of routine individuated service data for antenatal HIV surveillance in the Western Cape, Research Square Platform LLC.
- HIV incidence among women engaging in sex work in sub-Saharan Africa: a systematic review and meta-analysis, Cold Spring Harbor Laboratory.
- Can routine antenatal data be used to assess HIV antiretroviral therapy coverage among pregnant women? Evaluating the validity of different data sources in the Western Cape, South Africa, Cold Spring Harbor Laboratory.
- Establishing the health and wellbeing needs of mining host community in Brazil, Chile and Peru: a mixed-method approach to identify priority areas for action to help communities meet their SDG3 targets, Research Square Platform LLC.
- Use of Routinely Collected Blood Donation Data for Expanded Hiv and Syphilis Surveillance in Blantyre District, Malawi, Research Square Platform LLC.
- Key population size, HIV prevalence, and ART coverage in sub-Saharan Africa: systematic collation and synthesis of survey data, Cold Spring Harbor Laboratory.
- Health and Wellbeing Needs and Priorities in Mining Host Communities in South Africa: A Mixed-Methods Approach For Identifying Key SDG3 Targets, Research Square Platform LLC.
- Consolidating strategic information to monitor progress against the UNAIDS 90-90-90 targets: evaluating the operational feasibility of an electronic HIV testing register in Cape Town, South Africa, Research Square Platform LLC.
- Consolidating strategic information to monitor progress against the UNAIDS 90-90-90 targets: evaluating the operational feasibility of an electronic HIV testing register in Cape Town, South Africa, Research Square Platform LLC.
- Consolidating Strategic Information to Monitor Progress Against the UNAIDS 90-90-90 Targets: Evaluating the Operational Feasibility of an Electronic HIV Testing Register in Cape Town, South Africa, Research Square Platform LLC.
- Digitising point of care HIV test results to accurately measure, and improve performance towards, the UNAIDS 90-90-90 targets, Cold Spring Harbor Laboratory.
- The Continuing Value of CD4 Cell Count Monitoring for Differential HIV Care and Surveillance (Preprint), JMIR Publications Inc..
- Authorship Correction: Sampling Key Populations for HIV Surveillance: Results From Eight Cross-Sectional Studies Using Respondent-Driven Sampling and Venue-Based Snowball Sampling (Preprint), JMIR Publications Inc..
- Know Your Epidemic, Strengthen Your Response: Developing a New HIV Surveillance Architecture to Guide HIV Resource Allocation and Target Decisions (Preprint), JMIR Publications Inc..
- Strengthening Routine Data Systems to Track the HIV Epidemic and Guide the Response in Sub-Saharan Africa, JMIR Publications Inc..
- Strengthening Routine Data Systems to Track the HIV Epidemic and Guide the Response in Sub-Saharan Africa (Preprint), JMIR Publications Inc..
- Know Your Epidemic, Strengthen Your Response: Developing a New HIV Surveillance Architecture to Guide HIV Resource Allocation and Target Decisions, JMIR Preprints.
- Research group
-
Research projects
Measurement and Surveillance of HIV Epidemics (MeSH) consortium funded by the Bill & Melinda Gates Foundation. Deputy Director and then Director. Approx. $10.5 million US 2015 to 2023.
Sustainable Development Goals Health and Wellbeing (SDG-HaW) consortium funded by Anglo American Group Foundation. Co-director. Approx. $2.3 million US 2018 to 2023.
Current PhD students
Blake Hansen (LSHTM): The DREAMS Partnership: who was reached with a specific combination of interventions and what was the resulting impact on HIV-related, behavioural and social outcomes?
Kombatende Sikombe (LSHTM): Evaluating HIV care and treatment outcomes among adolescents living with HIV in Zambia.
Nisha Jacob (University of Cape Town): Feasibility, validity and utility of digitised HIV testing data as key components of HIV case-based surveillance in South Africa.
Advisory group member to Harriet Jones (LSHTM): The analysis and use of the Zimbabwe Sister’s programme data.
- Teaching activities
-
I am the module lead for Key Issues in Global Public Health (HAR675).
- Professional activities and memberships
-
- ScHARR Impact Lead
- Global Health Theme Lead
- Member of the UNAIDS M-TAG
- Member of the International AIDS Society
- Academic reviewer for a wide range of journals, including Nature, Nature Communications, and JAMA Network Open