Dr Ahmed Iqbal

All publications

Journal articles

• Iqbal A, Storey RF & Ajjan RA (2022) Prolonged Inflammatory Response Post-Hypoglycemia: Mechanistic Insights Into the Relationship Between Low Glucose and Cardiovascular Risk. Diabetes, 71(12), 2483-2485.
• Arshad MF, Iqbal A, Weeks J, Fonseca I, Munir A & Bennet W (2022) Hypertonic saline for severe symptomatic hyponatraemia: real-world findings from the UK.. Endocr Connect.
• Dowey R, Cole J, Roger Thompson AA, Hull RC, Huang C, Whatmore J, Iqbal A, Bradley KL, McKenzie J, Lawrie A , Condliffe AM et al (2022) Enhanced neutrophil extracellular trap formation in COVID-19 is inhibited by the PKC inhibitor ruboxistaurin. ERJ Open Research. View this article in WRRO
• Heller SR, Geybels MS, Iqbal A, Liu L, Wagner L & Chow E (2022) A higher non-severe hypoglycaemia rate is associated with an increased risk of subsequent severe hypoglycaemia and major adverse cardiovascular events in individuals with type 2 diabetes in the LEADER study. Diabetologia, 65(1), 55-64. View this article in WRRO
• Mubarak Mohamed AS, Iqbal A, Prasad S, Hoggard N & Blackburn D (2021) Cushing’s disease presenting with psychosis. Practical Neurology, 21(4), 351-353.
• Iqbal A, Greig M, Fahad Arshad M, Julian TH, Ee Tan S & Elliott J (2021) Higher admission activated partial thromboplastin time, neutrophil-lymphocyte ratio, serum sodium, and anticoagulant use predict in-hospital COVID-19 mortality in people with Diabetes: Findings from Two University Hospitals in the U.K. Diabetes Research and Clinical Practice, 108955-108955.
• Dowey R, Iqbal A, Heller SR, Sabroe I & Prince LR (2021) A bittersweet response to infection in diabetes ; targeting neutrophils to modify inflammation and improve host immunity. Frontiers in Immunology, 12.
• Ruan Y, Ryder REJ, De P, Field BCT, Narendran P, Iqbal A, Gandhi R, Harris S, Nagi D, Aziz U , Karra E et al (2021) A UK nationwide study of people with type 1 diabetes admitted to hospital with COVID-19 infection. Diabetologia, 64(8), 1717-1724. View this article in WRRO
• Bernjak A, Novodvorsky P, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Marques JLB, Jacques RM, Campbell MJ , Sheridan PJ et al (2021) Cardiac arrhythmias and electrophysiologic responses during spontaneous hyperglycaemia in adults with type 1 diabetes mellitus. Diabetes & Metabolism, 101237-101237.
• Dhami A, Iqbal A, Novodvorsky P & Grech ED (2020) Coronary Artery Spasm–Induced Cardiac Arrest Precipitated by Iodine Contrast Load in Unknown Pre-Existing Graves’ Disease. JACC: Cardiovascular Interventions, 13(16), e147-e149.
• Kelsall A, Iqbal A & Newell-Price J (2020) Adrenal incidentaloma: cardiovascular and metabolic effects of mild cortisol excess. Gland Surgery, 9(1), 94-104.
• Iqbal A & Newell-Price J (2019) Therapy of mild cortisol excess. Current Opinion in Endocrine and Metabolic Research, 8, 183-188.
• Novodvorsky P, Hussein Z, Arshad MF, Iqbal A, Fernando M, Munir A & Balasubramanian SP (2019) Two cases of spontaneous remission of primary hyperparathyroidism due to auto-infarction : different management and their outcomes. Endocrinology Diabetes and Metabolism Case Reports, 2019(1). View this article in WRRO
• Iqbal A, Prince LR, Novodvorsky P, Bernjak A, Thomas MR, Birch L, Lambert D, Kay LJ, Wright FJ, Macdonald IA , Jacques RM et al (2019) Effect of Hypoglycemia on Inflammatory Responses and the Response to Low Dose Endotoxemia in Humans.. Journal of Clinical Endocrinology and Metabolism, 104(4), 1187-1199. View this article in WRRO
• Chow E, Iqbal A, Walkinshaw E, Phoenix F, Macdonald IA, Storey RF, Ajjan R & Heller SR (2018) Prolonged Prothrombotic Effects of Antecedent Hypoglycemia in Individuals With Type 2 Diabetes. Diabetes Care, 41(12), 2625-2633. View this article in WRRO
• Novodvorsky P, Bernjak A, Robinson EJ, Iqbal A, Macdonald IA, Jacques RM, Marques JLB, Sheridan PJ & Heller SR (2018) Salbutamol-induced electrophysiological changes show no correlation with electrophysiological changes during hyperinsulinaemic-hypoglycaemic clamp in young people with Type 1 diabetes.. Diabetic Medicine, 35(9), 1264-1272. View this article in WRRO
• Iqbal A, Novodvorsky P & Heller SR (2018) Corrigendum: Recent updates on type 1 diabetes mellitus management for clinicians [Diabetes Metab J 2018;42:3-18] doi 10.4093/dmj.2018.42.1.3. Diabetes and Metabolism Journal, 42(2), 177-177. View this article in WRRO
• Iqbal A, Novodvorsky P & Heller SR (2018) Recent updates on type 1 diabetes mellitus management for clinicians. Diabetes and Metabolism Journal, 42(1), 3-18. View this article in WRRO
• Iqbal A & Heller SR (2017) The role of structured education in the management of hypoglycaemia. Diabetologia. View this article in WRRO
• Novodvorsky P, Bernjak A, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Parekh B, Jacques RM, Marques JLB , Sheridan PJ et al (2017) Diurnal Differences in Risk of Cardiac Arrhythmias During Spontaneous Hypoglycemia in Young People With Type 1 Diabetes. Diabetes Care, 40(5), 655-662. View this article in WRRO
• Iqbal A & Heller S (2016) Managing hypoglycaemia. Best Practice & Research Clinical Endocrinology & Metabolism, 30(3), 413-430. View this article in WRRO
• Iqbal A, Novodvorsky P, Lubina-Solomon A, Kew FM & Webster J (2016) Juvenile granulosa cell tumour of the ovary presenting with hyperprolactinaemic amenorrhoea and galactorrhoea. Endocrinology, Diabetes & Metabolism Case Reports, 2016. View this article in WRRO
• Tauschmann M, Thabit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P , Wilinska ME et al (2015) Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes. Journal of Diabetes Science and Technology, 9(6), 1346-1347. View this article in WRRO
• Thabit H, Elleri D, Leelarathna L, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska ME , Barnard KD et al (2015) Unsupervised home use of an overnight closed-loop system over 3-4 weeks: A pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes. Diabetes, Obesity and Metabolism, 17(5), 452-458. View this article in WRRO
• Barnard KD, Wysocki T, Thabit H, Evans ML, Amiel S, Heller S, Young A & Hovorka R (2015) Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting. Diabetic Medicine, 32(5), 601-608.
• Taylor PN, Minassian C, Rehman A, Iqbal A, Draman MS, Hamilton W, Dunlop D, Robinson A, Vaidya B, Lazarus JH , Thomas S et al (2014) TSH Levels and Risk of Miscarriage in Women on Long-Term Levothyroxine: A Community-Based Study. The Journal of Clinical Endocrinology & Metabolism, 99(10), 3895-3902.
• Thabit H, Lubina-Solomon A, Stadler M, Leelarathna L, Walkinshaw E, Pernet A, Allen JM, Iqbal A, Choudhary P, Kumareswaran K , Nodale M et al (2014) Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study. The Lancet Diabetes & Endocrinology, 2(9), 701-709. View this article in WRRO
• Taylor PN, Iqbal A, Minassian C, Sayers A, Draman MS, Greenwood R, Hamilton W, Okosieme O, Panicker V, Thomas SL & Dayan C (2014) Falling Threshold for Treatment of Borderline Elevated Thyrotropin Levels—Balancing Benefits and Risks. JAMA Internal Medicine, 174(1), 32-32.
• Iqbal AM, Blackburn D, Rafiq M & Sharrack B (2013) Wegener's granulomatosis presenting with multiple cranial nerve palsies and pachymeningitis. Practical Neurology, 13(3), 193-195.
• Taylor PN, Panicker V, Sayers A, Shields B, Iqbal A, Bremner AP, Beilby JP, Leedman PJ, Hattersley AT, Vaidya B , Frayling T et al (2011) A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement. European Journal of Endocrinology, 164(5), 773-780.
• Khorashad JS, Anand M, Marin D, Saunders S, Al-Jabary T, Iqbal A, Margerison S, Melo JV, Goldman JM, Apperley JF & Kaeda J (2006) The presence of a BCR-ABL mutant allele in CML does not always explain clinical resistance to imatinib. Leukemia, 20(4), 658-663.
• Hierons R () Configuration Testing of an Artificial Pancreas System using a Digital Twin: An Evaluative Case Study. Software Testing Verification and Reliability, 35(2).
• Arshad MF & Iqbal A () Use of hypertonic saline in severe symptomatic hyponatraemia; results from a national survey of endocrinologists in the United Kingdom. Endocrine.
• Arshad MF, Walkinshaw E, Solomon AL, Bernjak A, Rombach I, Little SA, Shaw JAM, Heller SR & Iqbal A () Diabetic autonomic neuropathy does not impede improvement in hypoglycaemia awareness in adults: Sub‐study results from the HypoCOMPaSS trial. Diabetic Medicine.
• Bernjak A, Iqbal A, Heller S & Clayton R () Hypoglycaemia combined with mild hypokalaemia reduces the heart rate and causes abnormal pacemaker activity in a computational model of a human sinoatrial cell.. Journal of the Royal Society Interface. View this article in WRRO

Chapters

• Iqbal A, Chow EYK, Jones TW & Heller SR (2024) Hypoglycaemia in Diabetes (pp. 579-601). Wiley
• Iqbal A, Chaudhury T & Heller S (2024) Hypoglycemia, insulin resistance, and cardiovascular disease: A possible link, Metabolic Syndrome (pp. 597-608). Elsevier
• Iqbal A & Heller S () Clinical management of type 1 diabetes, Advanced Nutrition and Dietetics in Diabetes (pp. 60-66). John Wiley & Sons, Ltd

Conference proceedings papers

• Berry S, Iqbal A, Newell-Price JDC & Debono M (2024) 6927 Metyrapone to reset the nocturnal cortisol rhythm in Mild Autonomous Cortisol Secretion (MACS) - safety and impact on cardiometabolic risk factors. Journal of the Endocrine Society, Vol. 8(Supplement_1). Boston, USA, 1 June 2024 - 1 June 2024. View this article in WRRO
• Arshad M & Iqbal A (2024) 5147 Use of hypertonic saline in severe symptomatic hyponatraemia; results from a national survey from United Kingdom. Journal of the Endocrine Society, Vol. 8(Supplement_1). Boston, USA, 1 June 2024 - 1 June 2024. View this article in WRRO
• HAUGHTON S, RILEY D, FAHAD ARSHAD M, AZMI S, MALIK RA, ALAM U & IQBAL A (2024) 946-P: Insulin Pump Therapy in Type 1 Diabetes—a Real-World Study of Mortality and Clinical Outcomes. Diabetes, Vol. 73(Supplement_1)
• Idrissi M, Buchipudi A, Kempegowda P, Choudhary P, Mayhew SS, Persad K, Page C, Yee ALJ, Iqbal A & DEKODE T (2024) Characteristics of presentation and management of people admitted with severe hypoglycaemia highlight the need for targeted educational interventions to mitigate occurrences - Pilot data from DEKODE Hypoglycaemia study. Clinical Medicine, Vol. 24 (pp 100176-100176)
• Iqbal A, Haughton S, Riley D, Arshad MF, Azmi S, Malik RA & Alam U (2024) Insulin pump therapy in type 1 diabetes: a real-world study of mortality and clinical outcomes. DIABETOLOGIA, Vol. 67 (pp S371-S371)
• Forteath C, McNeilly AD, Kerr J, Deyell J, Gallagher J, Iqbal A, Arshad MF, Stienstra R, Evans ML, Thorens B , Pederson-Bjergaard U et al (2023) Recurrent hypoglycaemia induces pro-inflammatory priming of BMDMs and promotes vascular dysfunction in a mouse model of type 2 diabetes and CVD. DIABETOLOGIA, Vol. 66(SUPPL 1) (pp S408-S409)
• Iqbal A, Arshad M, Julian T, Tan S, Greig M & Elliott J (2021) Higher admission activated partial thromboplastin time, neutrophil-lymphocyte ratio, serum sodium, and anticoagulant use predict in-hospital covid-19 mortality in people with diabetes: Findings from two university hospitals in the UK. DIABETIC MEDICINE, Vol. 38
• Novodvorsky P, Bernjak A, Smith A, Downs E, Arshad MF, Oprescu AI, Jacques RM, Lee J, Ahmed I & Heller SR (2020) Electrophysiological responses to hypoglycaemia in people with type 1 diabetes and impaired awareness of hypoglycaemia. DIABETOLOGIA, Vol. 63(SUPPL 1) (pp S359-S360)
• Arshad MF, Kaluarachchi V, Iqbal A, Munir A & Newell-Price JDC (2020) SUN-299 Flash Glucose Sensor Monitoring for Patients with Endogenous Hyperinsulinaemic Hypoglycaemia. Journal of the Endocrine Society, Vol. 4(Supplement_1)
• Mohamed AM, Blackburn D, Iqbal A & Prasad S (2019) 047 An unusual cause of psychosis. Journal of Neurology Neurosurgery & Psychiatry, Vol. 90(12) (pp a21)
• Iqbal A, Prince L, Novodvorsky P, Bernjak A, Thomas M, Birch L, Lambert D, Kay L, Wright F, Jacques R , Storey R et al (2018) Acute hypoglycaemia results in increased activation of responses to an inflammatory challenge induced 48 hours later in human subjects. DIABETOLOGIA, Vol. 61 (pp S446-S446)
• Bernjak A, Chow E, Lee J, Iqbal A, Lubina-Solomon A, Walkinshaw E, Macdonald IA, Heller SR, Clayton RH & Sheridan PJ (2017) Pharmacological autonomic blockade during experimental hypoglycaemia exacerbates cardiac repolarisation abnormalities. DIABETOLOGIA, Vol. 60 (pp S74-S74)
• Novodvorsky P, Bernjak A, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Jacques RM, Sheridan PJ & Heller SR (2017) Risk of cardiac arrhythmias and electrophysiological responses during spontaneous hyperglycaemia in young people with type 1 diabetes. DIABETOLOGIA, Vol. 60 (pp S534-S534)
• Iqbal A, Thomas M, Novodvorsky P, Bernjak A, Birch L, Lambert D, Kay L, Wright F, Prince L, Francis S , Storey R et al (2017) Hypoglycaemia increases platelet reactivity and promotes formation of proatherogenic platelet-leucocyte aggregates. DIABETOLOGIA, Vol. 60 (pp S532-S532)
• Iqbal A, Thomas M, Novodvorsky P, Bernjak A, Birch L, Lambert D, Kay L, Wright F, Prince L, Francis S , Storey R et al (2017) Effect of Hypoglycemia on Platelet Reactivity and Platelet-Leukocyte Kinetics. DIABETES, Vol. 66 (pp A41-A41)
• Bernjak A, Chow E, Lee J, Iqbal A, Lubina-Solomon A, Walkinshaw E, Heller SR, Clayton RH & Sheridan PJ (2017) Pharmacological Autonomic Blockade Exacerbates Cardiac Repolarization Abnormalities during Experimental Hypoglycemia. DIABETES, Vol. 66 (pp A95-A95)
• Novodvorsky P, Bernjak A, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Jacques RMJ, Sheridan PJ & Heller S (2017) Risk of cardiac arrhythmias and electrophysiological responses during spontaneous hypoglycaemia and hyperglycaemia in young people with Type 1 diabetes. DIABETIC MEDICINE, Vol. 34 (pp 34-35)
• Thomas MR, Iqbal A, Outteridge SN, Judge HM, Dockrell DH, Sabroe I & Storey RF (2016) Platelet P2Y12 inhibitors enhance expansion of the intermediate monocyte population following systemic inflammation in humans. EUROPEAN HEART JOURNAL, Vol. 37 (pp 904-904)
• Iqbal A, Novodvorksy P, Bernjak A, Chow E, Birch L, Lambert D, Kay L, Wright FJ, Prince L, Francis S , Sabroe I et al (2016) Hypoglycemia Increases Circulating Proatherogenic Intermediate Monocytes in Healthy Volunteers. DIABETES, Vol. 65 (pp A104-A104)
• Novodvorsky P, Bernjak A, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Jacques R, Marques JLB, Sheridan PJ & Heller SR (2016) Risk of Cardiac Arrhythmias during Spontaneous Hypoglycemia in Young People with Type 1 Diabetes. DIABETES, Vol. 65 (pp A101-A101)
• Thabit H, Elleri D, Leelarathna L, Allen J, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska M , Barnard K et al (2015) Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes. The Lancet, Vol. 385 (pp S96-S96)
• Habit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska ME , Heller SR et al (2014) Three to four weeks of overnight closed loop insulin delivery during free living: analysis of randomised crossover studies in adults and adolescents with type 1 diabetes. DIABETOLOGIA, Vol. 57 (pp S89-S89)
• Tauschmann M, Thabit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P , Heller SR et al (2014) Factors predictive of overnight closed loop performance during free living in children and adults with type 1 diabetes. DIABETOLOGIA, Vol. 57 (pp S414-S414)
• Barnard K, Thabit H, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Nisbet C, Pernet A, Leelarathna L, Allen J , Tinati T et al (2014) Overnight Closed-Loop Insulin Delivery: Psychosocial Impact for Adults with Type 1 Diabetes. DIABETES, Vol. 63 (pp A198-A198)
• Thabit H, Lubina-Solomon A, Stadler M, Leelarathna L, Walkinshaw E, Pernet A, Allen JM, Iqbal A, Choudhary P, Kumareswaran K , Nodale M et al (2014) Four Weeks' Home Use of Overnight Closed-Loop Insulin Delivery in Adults with Type 1 Diabetes: A Multicentre, Randomised, Crossover Study. DIABETES, Vol. 63 (pp A61-A61)
• Chow E, Iqbal A, Bernjak A, Ajjan R & Heller SR (2014) Effect of hypoglycaemia on thrombosis and inflammation in patients with type 2 diabetes. The Lancet, Vol. 383 (pp S35-S35)
• Chow EYK, Iqbal A, Phoenix F, Heller SR & Ajjan R (2013) Hypoglycaemia promotes thrombosis and inflammation for at least one week in patients with type 2 diabetes. DIABETOLOGIA, Vol. 56 (pp S243-S243)
• Chow EYK, Iqbal A, Walkinshaw E, Solomon AL, Daly R, Judge HM, Storey RF & Heller SR (2013) Hypoglycemia Increases Platelet Reactivity in Patients With Type 2 Diabetes. DIABETES, Vol. 62 (pp A100-A100)
• Sokhi D, Iqbal A, Randall M & Sarangmat N (2012) I CANNOT SMILE, DOCTOR. Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(Suppl 2) (pp A24.2-A24)
• Iqbal A, Blackburn D, Rafiq M & Sharrack B (2012) MULTIPLE CRANIAL NERVE PALSIES IN A YOUNG SINGER. Journal of Neurology, Neurosurgery & Psychiatry, Vol. 83(Suppl 2) (pp A18.1-A18)
• Berry S, Iqbal A, Newell-Price J & Debono M () Nocturnal metyrapone administration for cortisol suppression in macs: tolerability and impact on metabolic outcomes. Endocrine Abstracts
• Arshad MF, Iqbal A, Bury J, Wadsley J & Munir A () Functional or non-function pancreatic NET; Novel use of a flash glucose monitoring system. Endocrine Abstracts
• Follows J, Iqbal A & Allahabadia A () Four years of tolvaptan: experience from two large teaching hospitals. Endocrine Abstracts

Preprints

• Short E, Adcock IM, Al-Sarireh B, Ager A, Ajjan R, Akbar N, Akeroyd MA, Alsaleh G, Al-Sharbatee G, Alavian K , Amoaku W et al (2024) Defining an Ageing-Related Pathology, Disease or Syndrome: International Consensus Statement, Cold Spring Harbor Laboratory.