Professor Kate Ren

BSc (York), MPhil (Cantab), PhD (Sheffield)

Population Health, School of Medicine and Population Health

Professor of Statistical Health Technology Assessment

s.ren@sheffield.ac.uk
+44 114 222 0696

Full contact details

Professor Kate Ren
Population Health, School of Medicine and Population Health
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
Profile

I joined SCHARR in 2011 after completing a PhD in Probability and Statistics, specialising in Bayesian methods in clinical trial design at the University of Sheffield. My expertise lies in the development and application of Bayesian methods in Health Technology Assessment. My research interests include evidence synthesis methods (in particular indirect treatment comparisons with single-arm trials), survival extrapolation and structured expert elicitation.

I work as a member of SCHARR-TAG (an external assessment group for NICE technology appraisals). I have extensive experience in critiquing statistical methods used in NICE single technology appraisal submissions. I am also a member of NICE Appraisal Committee C.

I am an NIHR Advanced Fellow, currently working on a project titled “Improving the robustness of health technology funding decisions when evidence is from single-arm trials”.

Research interests
  • Network meta-analysis
  • Indirect treatment comparisons
  • Population-adjusted indirect comparisons
  • Survival extrapolation
  • Structured expert elicitation
  • Bayesian statistics in clinical trials and health economics
Publications

Show: Featured publications All publications

Journal articles

All publications

Journal articles

Conference proceedings papers

  • Goodacre S, Ren S, Essat M, Pandor A, Ren S, Clowes M, Bima P, Toyofuku M, McLatchie R, Bossone E & Wilson S (2024) 2613 Diagnostic accuracy of the aortic dissection detection risk score alone or with D-dimer for acute aortic syndromes: systematic review and meta-analysis. RCEM Annual Scientific Conference 2024 Abstracts (pp A9.1-A9) RIS download Bibtex download
  • Srivastava T, Gupta A, Gautam R, Hriday K & Ren S (2024) ARE WE DEALING WITH HETEROGENEITY IN NETWORK META-ANALYSIS APPROPRIATELY? A REVIEW OF NICE SUBMISSIONS. VALUE IN HEALTH, Vol. 27(6) (pp S403-S404) RIS download Bibtex download
  • Shah B, Challagulla S, Xu S, Williams R, Ren S, Srivastava T, Gautam R & Yang K (2024) Indirect Comparison of Efficacy of Zanubrutinib Versus Acalabrutinib in the Treatment of Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL). CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, Vol. 24 (pp S516-S517) RIS download Bibtex download
  • Harnan S, Hamilton J, Simpson E, Clowes M, Biz AN, Whyte S, Ren K, Cooper K, Abulafi M, Ball A , Benton S et al (2024) FAECAL IMMUNOCHEMICAL TESTS FOR PATIENTS IN PRIMARY CARE WITH SYMPTOMS OF COLORECTAL CANCER: SYSTEMATIC REVIEW AND MULTIPLE-THRESHOLD META-ANALYSIS. VALUE IN HEALTH, Vol. 27(12) RIS download Bibtex download
  • Ren K & Forsyth J (2024) ENHANCING EXPERT ELICITATION IN HEALTH TECHNOLOGY ASSESSMENT: PRACTICAL INSIGHTS AND RECOMMENDATIONS. VALUE IN HEALTH, Vol. 27(12) RIS download Bibtex download
  • Knowles M, Kroep S & Ren K (2024) COMPARATIVE EFFICACY OF TREATMENTS IN ADVANCED/METASTATIC PANCREATIC CANCER: DEMONSTRATING THE POWER OF MULTI-LEVEL NETWORK META REGRESSION. VALUE IN HEALTH, Vol. 27(12) RIS download Bibtex download
  • Dunnewind N, Ainsworth C, Ren S & Kroep S (2023) PRIORS ON BETWEEN- STUDY HETEROGENEITY IN BAYESIAN META-ANALYSIS MODELS: A SIMULATION STUDY USING HAMILTONIAN MONTE CARLO SAMPLING. VALUE IN HEALTH, Vol. 26(12) (pp S557-S557) RIS download Bibtex download
  • Ren S (2023) A NOVEL UNANCHORED SIMULATED TREATMENT COMPARISON APPROACH FOR TIME-TO-EVENT DATA. VALUE IN HEALTH, Vol. 26(12) (pp S424-S424) RIS download Bibtex download
  • Sultana N & Ren S (2022) REVIEW OF METHODS USED TO ESTIMATE TREATMENT EFFECTS AGAINST RELEVANT COMPARATORS USING EVIDENCE FROM SINGLE-ARM STUDIES IN NICE SINGLE TECHNOLOGY APPRAISALS. VALUE IN HEALTH, Vol. 25(12) (pp S10-S10) RIS download Bibtex download
  • Zhu D, Ren S, Mills K, Lemp-Hull J, Dhariwal M & Srivastava T (2022) RATE OF COMPLETE SPECTACLE INDEPENDENCE WITH A TRIFOCAL IOL: A SYSTEMATIC LITERATURE REVIEW AND META-ANALYSIS. VALUE IN HEALTH, Vol. 25(12) (pp S378-S378) RIS download Bibtex download
  • Ren S, Strong M & Welton N (2022) AN EXTENDED SIMULATED TREATMENT COMPARISON APPROACH ACCOUNTING FOR UNOBSERVED CONFOUNDING IN INDIRECT COMPARISONS FOR SINGLE-ARM TRIALS. VALUE IN HEALTH, Vol. 25(12) (pp S358-S358) RIS download Bibtex download
  • Thokala P, Stevenson M, Kumar VM, Ren S, Chapman R, Ellis A & Rind D (2019) PRO15 COST-EFFECTIVENESS OF NUSINERSEN AND ONASEMNOGENE ABEPARVOVEC FOR INFANTILE-ONSET SPINAL MUSCULAR ATROPHY (TYPE I SMA) IN THE US. Value in Health, Vol. 22 (pp S337-S338) RIS download Bibtex download
  • Ren S, Oakley JE & Stevens JW (2017) EVIDENCE SYNTHESIS FOR HEALTH TECHNOLOGY ASSESSMENT WITH LIMITED STUDIES. VALUE IN HEALTH, Vol. 20(9) (pp A770-A770) RIS download Bibtex download
  • Harnan S, Ren S, Gomersall T, Everson-Hock E, Sutton A, Dhanasiri S & Kulasekararaj A (2014) Systematic Review and Meta-Analysis of the Association Between Transfusion Independence (TI) and Overall Survival (OS) in Patients (pts) with Myelodysplastic Syndromes (MDS). Blood, Vol. 124(21) (pp 1934-1934) RIS download Bibtex download
  • Almond C, Stevens JW, Ren K & Batty A (2013) The Estimated Survival of Patients with Double Refractory Chronic Lymphocytic Leukaemia; A Reanalysis of NICE TA202 Using Bayesian Methodology to Model Observed Data. Value in Health, Vol. 16(7) (pp A397-A397) RIS download Bibtex download

Posters

  • Zhu D, Ren S, Mills K, Lemp-Hull J, Dhariwal M & Srivastava T (2022) MT2 Rate of Complete Spectacle Independence With a Trifocal IOL: A Systematic Literature Review and Meta-Analysis. RIS download Bibtex download
  • Ghabri S, Simpson EL, Ren S, Hock E, Archer R, Binard A, Pers Y, Stevens JW, Herpin C & Stevenson M (2018) PMS4 - RHEUMATOID ARTHRITIS TREATED WITH SIX-MONTHS OF FIRST-LINE BIOLOGIC OR BIOSIMILAR THERAPY: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS. RIS download Bibtex download
  • Ren S, Oakley J & Stevens JW (2018) Evidence synthesis with limited studies. HTAi 2018, Vancouver, Canada. RIS download Bibtex download
  • Ren S, Oakley J & Stevens JW (2017) Evidence synthesis for health technology assessment with limited studies.. . ISPOR Glasgow 2017. RIS download Bibtex download
  • Goodacre S (2014) PRE-HOSPITAL NON-INVASIVE VENTILATION FOR ACUTE RESPIRATORY FAILURE: A SYSTEMATIC REVIEW AND NETWORK META ANALYSIS. RIS download Bibtex download
  • Ren S, Cooper K, Cooper J, Smith H & Shaikh S A systematic review and network meta - analysis of pharmacological therapies used for patients with advanced Parkinson's disease (2014). RIS download Bibtex download
  • Goodacre S, Pandor A, Poku E, Stevens JW, Ren S & Cantrell A Pre-hospital non-invasive ventilation for acute respiratory failure: a systematic review and network meta-analysis. 999 EMS Research Forum Conference. RIS download Bibtex download

Preprints

Grants
  • NIHR Evidence Synthesis Group (2023-2028, £4,507,538) Co-investigator.
  • NIHR Technology Assessment Reviews (2022-2027, £6,999,908) Co-investigator.
  • NIHR Advanced Fellowship (2021-2025, £368,269) Principal investigator.
  • NIHR HTA Programme: Effectiveness of interventions for fatigue in long-term conditions (2023-2025, £332,575) Co-investigator.
  • NIHR HTA Programme: Diagnostic strategies for suspected acute aortic syndrome (2023-2024, £184,095) Co-investigator.
  • NIHR HTA Programme: Medically unexplained symptoms: primary care intervention (2015-2017, £171,405) Co-investigator.
Teaching interests

Evidence synthesis, survival analysis