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close up image of mitochondria in fibroblasts
Mitochondria in fibroblasts

World Alzheimer’s Month - Understanding the mitochondria

As part of World Alzheimer’s Month, we’re shining a light on the Mortiboys Lab, a lab dedicated to understanding the mitochondria in neurodegenerative diseases.
Professor Oliver Bandmann

Professor Oliver Bandmann honoured for Parkinson’s research

Professor Oliver Bandmann, Co-Director of the Neuroscience Institute has been awarded the 2024 Tom Isaacs Award in recognition of his outstanding Parkinson’s research.
brain scan

Ongoing dementia studies at the Neuroscience Institute

Our dementia research is internationally recognised and brings together clinicians, scientists and researchers from multiple disciplines. As part of World Alzheimer’s Month, we’re shining a spotlight on some of our ongoing studies.
image of astrocytes under microscope

Research study identifies a new therapeutic target for Alzheimer’s disease

Research from the Neuroscience Institute identifies the impact of a reduction in astrocytes in the hexokinase 1 (HK1) enzyme in Alzheimer’s disease, paving a new pathway for potential treatments.
Image of genetic testing

Innovative gene therapy programme paves the way for new treatments for neurodegenerative diseases

An innovative gene therapy programme which could pave the way for novel treatments for neurodegenerative diseases, has been launched at the University of Sheffield in collaboration with the Cell and Gene Therapy Catapult.

Neurons

Frequent strenuous exercise increases the chance of developing MND in genetically at risk individuals

Frequent strenuous exercise increases the risk of developing motor neurone disease (MND) in certain people, new research from the University of Sheffield has found.
Neuron cells system. Conceptual medical image. Glowing synapse. Healthcare concept.

Rinri Therapeutics raises £10 million to advance its novel stem cell therapy to restore hearing loss

Rinri Therapeutics, a spin out company based on research undertaken in the Neuroscience Institute at The University of Sheffield, has raised £10m to support the development of novel stem cell therapy to reverse sensorineural hearing loss.
Old and newly made dopamine-producing nerve cells in the zebrafish brain

Parkinson's gene may impair how new neurons are made throughout our lifetime

A gene defect linked to Parkinson’s disease may not only cause the early death of neurons, but also impair the process that generates neurons in the brain throughout our lifetime, a new study has revealed.

Artwork
Artist impression of the new Gene Therapy Innovation Manufacturing Centre

New gene therapy innovation centre to advance scientific discoveries into life-changing treatments

A pioneering gene therapy innovation centre at the University of Sheffield is set to advance scientific discoveries into promising treatment options for millions of patients with life-threatening diseases.