Professor Nick Monk

All publications

Books

• Monk NAM & Maroto M (2008) Cellular Oscillatory Mechanisms. Springer.

Journal articles

• Chaffin S, Monk NAM, Rees JM & Zimmerman WB (2024) Dissolved nutrient gas uptake and fluid mixing by bubble-mediated mass transfer in tall fermenters — A theoretical study. Food and Bioproducts Processing, 145, 136-147.
• Jaeger J & Monk N (2021) Dynamical modules in metabolism, cell and developmental biology. Interface Focus, 11(3).
• Economou AD, Monk NAM & Green JBA (2020) Perturbation analysis of a multi-morphogen Turing reaction-diffusion stripe patterning system reveals key regulatory interactions. Development, 147(20).
• Verd B, Monk NAM & Jaeger J (2019) Modularity, criticality, and evolvability of a developmental gene regulatory network. eLife, 8. View this article in WRRO
• Holland BL, Monk NAM, Clayton RH & Osborne CP (2019) A theoretical analysis of how plant growth is limited by carbon allocation strategies and respiration. in silico Plants (isP), 1(1). View this article in WRRO
• Hartwell RD, England SJ, Monk NAM, van Hateren NJ, Baxendale S, Marzo M, Lewis KE & Whitfield TT (2019) Anteroposterior patterning of the zebrafish ear through Fgf- and Hh-dependent regulation of hmx3a expression. PLoS Genetics, 15(4). View this article in WRRO
• Jaeger J & Monk N (2015) Everything flows. EMBO reports, 16(9), 1064-1067.
• Kasprzewska A, Carter R, Swarup R, Bennett M, Monk N, Hobbs JK & Fleming A (2015) Auxin influx importers modulate serration along the leaf margin. The Plant Journal, 83(4), 705-718. View this article in WRRO
• Whitfield TT & Monk N (2014) Julian Hart Lewis, FRS (1946-2014) Obituary. DEVELOPMENTAL CELL, 29(5), 507-509.
• Jaeger J & Monk N (2014) Bioattractors: dynamical systems theory and the evolution of regulatory processes.. J Physiol, 592(11), 2267-2281.
• Shimizu H, Woodcock SA, Wilkin MB, Trubenová B, Monk NAM & Baron M (2014) Compensatory flux changes within an endocytic trafficking network maintain thermal robustness of Notch signaling.. Cell, 157(5), 1160-1174.
• Savage N, Yang TJW, Chen CY, Lin KL, Monk NAM & Schmidt W (2013) Positional Signaling and Expression of ENHANCER OF TRY AND CPC1 Are Tuned to Increase Root Hair Density in Response to Phosphate Deficiency in Arabidopsis thaliana. PLoS ONE, 8(10). View this article in WRRO
• Fischer S, Houston P, Monk NAM & Owen MR (2013) Is a persistent global bias necessary for the establishment of planar cell polarity?. PLoS One, 8(4), e60064. View this article in WRRO
• Jaeger J, Irons D & Monk N (2012) The Inheritance of Process: A Dynamical Systems Approach. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 318(8), 591-612.
• Gaffney EA, Monk NAM, Baker RE & Seirin Lee S (2012) Reply to Correspondence: No Oscillations in Real Activator-Inhibitor Systems in Accomplishing Pattern Formation. Bulletin of Mathematical Biology, 1-4.
• Benitez M, Monk NAM & Alvarez-Buylla ER (2011) Epidermal Patterning in Arabidopsis: Models Make a Difference. J EXP ZOOL PART B, 316B(4), 241-253.
• Kuwabara A, Backhaus A, Malinowski R, Bauch M, Hunt L, Nagata T, Monk N, Sanguinetti G & Fleming A (2011) A shift toward smaller cell size via manipulation of cell cycle gene expression acts to smoothen Arabidopsis leaf shape.. Plant Physiol, 156(4), 2196-2206.
• Lee SS, Gaffney EA & Monk NAM (2010) The Influence of Gene Expression Time Delays on Gierer-Meinhardt Pattern Formation Systems. B MATH BIOL, 72(8), 2139-2160.
• Schamberg S, Houston P, Monk NAM & Owen MR (2010) Modelling and analysis of planar cell polarity.. Bull Math Biol, 72(3), 645-680.
• Backhaus A, Kuwabara A, Bauch M, Monk N, Sanguinetti G & Fleming A (2010) LEAFPROCESSOR: a new leaf phenotyping tool using contour bending energy and shape cluster analysis.. New Phytol, 187(1), 251-261.
• Irons DJ, Wojcinski A, Glise B & Monk NAM (2010) Robustness of positional specification by the Hedgehog morphogen gradient. Developmental Biology, 342(2), 180-193. View this article in WRRO
• Momiji H & Monk NAM (2009) Oscillatory Notch-pathway activity in a delay model of neuronal differentiation.. Phys Rev E Stat Nonlin Soft Matter Phys, 80(2 Pt 1), 021930.
• Marato M & Monk NAM (2008) Advances in Experimental Medicine and Biology: Preface. Advances in Experimental Medicine and Biology, 641.
• Momiji H & Monk NAM (2008) Dissecting the dynamics of the Hes1 genetic oscillator.. J Theor Biol, 254(4), 784-798.
• Jaeger J, Irons D & Monk N (2008) Regulative feedback in pattern formation: towards a general relativistic theory of positional information. DEVELOPMENT, 135(19), 3175-3183.
• Savage NS, Walker T, Wieckowski Y, Schiefelbein J, Dolan L & Monk NAM (2008) A mutual support mechanism through intercellular movement of CAPRICE and GLABRA3 can pattern the Arabidopsis root epidermis.. PLoS Biol, 6(9), e235. View this article in WRRO
• Monk N (2008) Using mathematical models to probe dynamic expression data.. SEB Exp Biol Ser, 61, 93-111.
• Bennett M & Monk N (2008) The flowering of systems approaches in plant and crop biology.. New Phytol, 179(3), 567-568.
• Momiji H & Monk NAM (2008) Oscillatory expression of Hes family transcription factors: insights from mathematical modelling.. Adv Exp Med Biol, 641, 72-87.
• Page KM, Monk NAM & Maini PK (2007) Speed of reaction diffusion in embryogenesis. Physical Review E - Statistical, Nonlinear, and Soft Matter Physics, 76(1).
• Irons DJ & Monk NAM (2007) Identifying dynamical modules from genetic regulatory systems: applications to the segment polarity network.. BMC Bioinformatics, 8, 413. View this article in WRRO
• Gaffney EA & Monk NAM (2006) Gene expression time delays and turing pattern formation systems. Bulletin of Mathematical Biology, 68(1), 99-130.
• Veflingstad SR, Plahte E & Monk NAM (2005) Effect of time delay on pattern formation: Competition between homogenisation and patterning. Physica D: Nonlinear Phenomena, 207(3-4), 254-271.
• Page KM, Maini PK & Monk NAM (2005) Complex pattern formation in reaction-diffusion systems with spatially varying parameters. Physica D: Nonlinear Phenomena, 202(1-2), 95-115.
• Monk N (2004) Development: dissecting the dynamics of segment determination.. Curr Biol, 14(17), R705-R707.
• Monk N (2004) Developmental biology - Asymmetric fixation. NATURE, 427(6970), 111-112.
• Monk NAM (2003) Unravelling Nature's networks.. Biochem Soc Trans, 31(Pt 6), 1457-1461.
• Monk N & Lawrence N (2003) Unravelling Nature's Networks: From Microarray and Proteomic Analysis to Systems Biology: University of Sheffield, 21–22 July 2003. The Biochemist, 25(6), 40-41.
• Monk NAM (2003) Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.. Curr Biol, 13(16), 1409-1413.
• Page K, Maini PK & Monk NAM (2003) Pattern formation in spatially heterogeneous Turing reaction-diffusion models. Physica D: Nonlinear Phenomena, 181(1-2), 80-101.
• Thomas A, Cannings R, Monk NAM & Cannings C (2003) On the structure of protein-protein interaction networks. Biochemical Society Transactions, 31(6), 1491-1496.
• Page KM, Maini PK, Monk NAM & Stern CD (2001) A model of primitive streak initiation in the chick embryo. Journal of Theoretical Biology, 208(4), 419-438.
• Monk NA (2000) Elegant hypothesis and inelegant fact in developmental biology.. Endeavour, 24(4), 170-173.
• Monk NA (1998) Restricted-range gradients and travelling fronts in a model of juxtacrine cell relay.. Bull Math Biol, 60(5), 901-918.
• Monk NAM (1998) Towards a quantum pregeometric description of space-time. Endeavour, 22(1), 27-30.
• Monk NAM & Hiley BJ (1998) A unified algebraic approach to quantum theory. Foundations of Physics Letters, 11(4), 371-377.
• Monk NAM (1997) Cell communities and robustness in development. Bulletin of Mathematical Biology, 59(6), 1183-1189.
• Monk NAM (1997) The community effect and ectoderm-mesoderm interaction inXenopus muscle differentiation. Bulletin of Mathematical Biology, 59(3), 409-425.
• Monk NAM (1997) Conceptions of space-time: Problems and possible solutions. Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics, 28(1), 1-34.
• Collier JR, Monk NAM, Maini PK & Lewis JH (1996) Pattern Formation by Lateral Inhibition with Feedback: a Mathematical Model of Delta-Notch Intercellular Signalling. Journal of Theoretical Biology, 183(4), 429-446.
• Jaeger J & Monk N () The flow of substance: a reply to Horsting & Hartjes. EMBO reports.
• Hale R, Brittle AL, Fisher KH, Monk NAM & Strutt D () Cellular interpretation of the long-range gradient of Four-jointed activity in the Drosophila wing. eLife, 4. View this article in WRRO
• Chaffin S, Monk N, Rees J & Zimmerman W () Re-Entrant Corner for a White-Metzner Fluid. Fluids, 6(7), 241-241.

Chapters

• Jaeger J & Monk N (2021) Dynamical Modularity of the Genotype-Phenotype Map, Evolutionary Systems Biology (pp. 245-280). Springer International Publishing
• Jaeger J & Monk NA (2013) Keeping the gene in its place In Lambert D & Chetland C (Ed.), The Intuitive Way of Knowing. A Tribute to Brian Goodwin Floris Books
• Monk N (2004) Spatial Patterning in Explicitly Cellular Environments: Activity-Regulated Juxtacrine Signalling, Natural Computing Series (pp. 211-225). Springer Berlin Heidelberg
• Monk NAM, Sherratt JA & Owen MR (2001) Spatiotemporal Patterning in Models of Juxtacrine Intercellular Signalling with Feedback, Mathematical Models for Biological Pattern Formation (pp. 165-192). Springer New York

Conference proceedings papers

• Irons D & Monk N (2009) Glypicans enhance robustness in Hedgehog gradient formation. MECHANISMS OF DEVELOPMENT, Vol. 126 (pp S285-S285)
• Monk N & Momiji H (2009) Delay-driven oscillations in the Notch signalling network. MECHANISMS OF DEVELOPMENT, Vol. 126 (pp S287-S287)
• Monk N (2008) Modelling the mutual support of differential cell fates in the Arabidopsis root epidermis. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, Vol. 150(3) (pp S45-S45)

Preprints

• Holland BL, Monk NAM, Clayton RH & Osborne CP (2023) Implementing a framework of carbon and nitrogen feedback responses into a plant resource allocation model, Cold Spring Harbor Laboratory.
• Petangoda J, Deisenroth MP & Monk NAM (2021) Learning to Transfer: A Foliated Theory, arXiv.
• Momiji H & Monk NAM (2009) Oscillatory Notch pathway activity in a delay model of neuronal differentiation, arXiv.
• Thomas A, Cannings R, Monk NAM & Cannings C (2003) On the structure of proten-protein interaction networks, arXiv.
• Economou AD, Monk NAM & Green JBA () Perturbation analysis of a multi-morphogen Turing Reaction-Diffusion stripe patterning system reveals key regulatory interactions.
• Hartwell RD, England SJ, Monk NAM, van Hateren NJ, Baxendale S, Marzo M, Lewis KE & Whitfield TT () Anteroposterior patterning of the zebrafish ear through Fgf- and Hh-dependent regulation of hmx3a expression.