Professor David G Kiely
BSc (Hons), MD, FRCP
Clinical Medicine, School of Medicine and Population Health
Honorary Professor of Pulmonary Vascular Medicine
Director of the Sheffield Pulmonary Vascular Disease Unit
Honorary Professor of Pulmonary Vascular Medicine
Full contact details
Clinical Medicine, School of Medicine and Population Health
Room M15, Floor M
Royal Hallamshire Hospital
Glossop Road
Sheffield
S10 2JF
- Profile
-
For enquiries please contact - ClinMed-Operational@sheffield.ac.uk
I graduated from the University of Edinburgh in 1991 and undertook a period of postgraduate research in Dundee examining the effects of hypoxia, hypercapnia and vasoactive peptides on the pulmonary circulation in man. I completed my clinical training in Cambridge and Papworth and was appointed as the Director of the Sheffield Pulmonary Vascular Disease Unit, in 2001.
Our pulmonary hypertension unit is one of the largest in the world and assesses and manages all forms of adult pulmonary hypertension. With colleagues I am also involved in delivering integrated services for patients with pulmonary embolism, managing the respiratory complications of connective disease and assessing fitness for emerging therapies such as autologous haemopoietic stem cell transplantation.
- Research interests
-
I am the Pulmonary Hypertension Research Theme lead on the Sheffield Teaching Hospitals Respiratory Medicine Research Executive and a Co-director of Donald Heath Research where I collaborate closely with Jim Wild and Andrew Swift (Imaging), Allan Lawrie (Pre-clinical models and drug discovery) and my clinical colleagues in pulmonary hypertension Robin Condliffe, Charlie Elliot, , Ian Sabore and Thanos Charalampopoulos.
My research is primarily focused on the assessment and classification of pulmonary hypertension and the use of multimodality imaging and artificial intelligence (AI) approaches to improve the diagnosis and classification of pulmonary hypertension.
I have participated in multiple randomised controlled trials in pulmonary hypertension leading to the licensing of new treatments and have helped translate new imaging techniques into routine clinical practice.
I currently participate in a number of research studies funded by the NIHR, MRC, Wellcome Trust and BHF and am part of a UK collaboration characterising genes and biomarkers in patients with pulmonary arterial hypertension. In 2017 I received an award from the NIHR and Royal College of Physicians recognising an outstanding contribution to research in the NHS.
- Publications
-
Show: Featured publications All publications
Featured publications
Journal articles
- Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood. Nature Communications, 12. View this article in WRRO
- The REPAIR Study : effects of macitentan on RV structure and function in pulmonary arterial hypertension. JACC: Cardiovascular Imaging.
- Repeatability and sensitivity to change of non-invasive end points in PAH: the RESPIRE study. Thorax, 76(10), 1032-1035.
- Assessing pulmonary hypertension severity in lung disease is a key step to improving outcomes: embrace resistance and don't be pressurised to go with the flow. European Respiratory Journal, 58(2), 2102008-2102008.
- A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach. EBioMedicine, 69. View this article in WRRO
- Right ventricular adaptation assessed using cardiac magnetic resonance predicts survival in pulmonary arterial hypertension. JACC: Cardiovascular Imaging, 14(6), 1271-1272. View this article in WRRO
- Pulmonary hypertension in association with lung disease : quantitative CT and artificial intelligence to the rescue? State-of-the-art review. Diagnostics, 11(4). View this article in WRRO
- A machine learning cardiac magnetic resonance approach to extract disease features and automate pulmonary arterial hypertension diagnosis. European Heart Journal - Cardiovascular Imaging, 22(2), 236-245. View this article in WRRO
- Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension. Circulation: Genomic and Precision Medicine, 14(1), 57-70. View this article in WRRO
- Current and future treatments of pulmonary arterial hypertension. British Journal of Pharmacology, 178(1), 6-30. View this article in WRRO
- Cardiac-MRI predicts clinical worsening and mortality in pulmonary arterial hypertension: a systematic review and meta-analysis. JACC: Cardiovascular Imaging. View this article in WRRO
- Maximal exercise testing using the incremental shuttle walking test can be used to risk stratify patients with pulmonary arterial hypertension. Annals of the American Thoracic Society. View this article in WRRO
- Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension. European Radiology, 30(9), 4918-4929. View this article in WRRO
- Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension. Circulation, 142(15), 1464-1484.
- EmPHasis-10 health-related quality of life score predicts outcomes in patients with idiopathic and connective tissue disease-associated pulmonary arterial hypertension: results from a UK multi-centre study. European Respiratory Journal. View this article in WRRO
- Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension. European Respiratory Journal, 55(6). View this article in WRRO
- Identification of Cardiac Magnetic Resonance Imaging Thresholds for Risk Stratification in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 201(4), 458-468. View this article in WRRO
- Screening strategies for pulmonary arterial hypertension. European Heart Journal Supplements, 21(Supplement_K), K9-K20. View this article in WRRO
- Utilising artificial intelligence to determine patients at risk of a rare disease : idiopathic pulmonary arterial hypertension. Pulmonary Circulation, 9(4). View this article in WRRO
- Exploring a physiotherapy well-being review to deliver community-based rehabilitation in patients with pulmonary hypertension. Pulmonary Circulation, 9(4). View this article in WRRO
- EXPRESS: Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI).. Pulmonary Circulation, 9(3). View this article in WRRO
- Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. The Lancet Respiratory Medicine, 7(3), 227-238. View this article in WRRO
- ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension. European Respiratory Journal, 53(2), 1800332-1800332.
- Diagnosis of Pulmonary Hypertension with Cardiac MRI: Derivation and Validation of Regression Models.. Radiology, 290(1). View this article in WRRO
- Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension. Circulation. Genomic and precision medicine, 11(10). View this article in WRRO
- The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension. European Respiratory Journal, 52(3), ---. View this article in WRRO
- CT derived left atrial size identifies left heart disease in suspected pulmonary hypertension: Derivation and validation of predictive thresholds. International Journal of Cardiology, 260, 172-177. View this article in WRRO
- British Thoracic Society Clinical Statement on Pulmonary Arteriovenous Malformations. Thorax, 72(12), 1154-1163.
- Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study. The Lancet Respiratory Medicine, 5(9), 717-726. View this article in WRRO
- Magnetic Resonance Imaging in the Prognostic Evaluation of Patients with Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 196(2). View this article in WRRO
- Cardiopulmonary assessment of patients with systemic sclerosis for hematopoietic stem cell transplantation: recommendations from the European Society for Blood and Marrow Transplantation Autoimmune Diseases Working Party and collaborating partners.. Bone Marrow Transplantation. View this article in WRRO
- Incremental Shuttle Walking Test Distance and Autonomic Dysfunction Predict Survival in Pulmonary Arterial Hypertension. The Journal of Heart and Lung Transplantation. View this article in WRRO
- 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Heart Journal, 37(1), 67-119.
- Statement on Pregnancy in Pulmonary Hypertension from the Pulmonary Vascular Research Institute. Pulmonary Circulation, 5(3), 435-465.
- CT features of pulmonary arterial hypertension and its major subtypes: a systematic CT evaluation of 292 patients from the ASPIRE Registry. Thorax, 70(4), 382-387. View this article in WRRO
- LGE Patterns in Pulmonary Hypertension Do Not Impact Overall Mortality. JACC: Cardiovascular Imaging, 7(12), 1209-1217.
- emPHasis-10: development of a health-related quality of life measure in pulmonary hypertension.. European Respiratory Journal, 43, 1106-1113. View this article in WRRO
- Management dilemmas in acute pulmonary embolism.. Thorax, 69(2), 174-180. View this article in WRRO
- Prognostic value of cardiovascular magnetic resonance imaging measurements corrected for age and sex in idiopathic pulmonary arterial hypertension.. Circ Cardiovasc Imaging, 7(1), 100-106.
- Primary pulmonary artery sarcoma and coexisting chronic thromboembolic pulmonary hypertension.. Am J Respir Crit Care Med, 188(5), e7-e8.
- Noninvasive estimation of PA pressure, flow, and resistance with CMR imaging: derivation and prospective validation study from the ASPIRE registry.. JACC Cardiovasc Imaging, 6(10), 1036-1047.
- Pulmonary hypertension in COPD: results from the ASPIRE registry.. Eur Respir J, 41(6), 1292-1301.
- Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension.. Am J Respir Crit Care Med, 187(3), 294-302.
- Improving safety in autologous HSCT for systemic sclerosis.. Lancet, 381(9872), 1081-1083.
- Pulmonary hypertension: diagnosis and management.. BMJ, 346, f2028.
- Diagnostic accuracy of cardiovascular magnetic resonance imaging of right ventricular morphology and function in the assessment of suspected pulmonary hypertension results from the ASPIRE registry.. J Cardiovasc Magn Reson, 14, 40. View this article in WRRO
- ASPIRE registry: assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre.. Eur Respir J, 39(4), 945-955.
- Black blood MRI has diagnostic and prognostic value in the assessment of patients with pulmonary hypertension. European Radiology, 1-8.
- Connective tissue disease-associated pulmonary arterial hypertension in the modern treatment era.. Am J Respir Crit Care Med, 179(2), 151-157.
- Improved outcomes in medically and surgically treated chronic thromboembolic pulmonary hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 177(10), 1122-1127.
- Initial results of the united kingdom audit of pulmonary arterial hypertension associated with connective tissue disease (CTD-PAH). EUROPEAN HEART JOURNAL, 28, 139-140.
- Inhaled iloprost for severe pulmonary hypertension. NEW ENGL J MED, 347(5), 322-329.
- Volume aspirated is an indicator of the success of manual aspiration in the treatment of spontaneous pneumothorax. THORAX, 55, A74-A74.
- Cardiopulmonary effects of endothelin-1 in man. CARDIOVASCULAR RESEARCH, 33(2), 378-386.
Other
All publications
Journal articles
- The spectrum of systemic sclerosis-associated pulmonary hypertension: Insights from the ASPIRE registry. The Journal of Heart and Lung Transplantation, 43(10), 1629-1639. View this article in WRRO
- Phosphodiesterase-5 Inhibitor Treatment is Associated with Improved Survival in Pulmonary Hypertension Associated with COPD in the PVRI GoDeep Meta-Registry. CHEST.
- Individualized survival predictions using state space model with longitudinal and survival data. Journal of The Royal Society Interface, 21(216). View this article in WRRO
- Association of risk assessment at diagnosis with healthcare resource utilization and health‐related quality of life outcomes in pulmonary arterial hypertension. Pulmonary Circulation, 14(3).
- Two prospective, multicenter studies for the identification of biomarker signatures for early detection of pulmonary hypertension (PH): The CIPHER and CIPHER‐MRI studies. Pulmonary Circulation, 14(2).
- A systematic review of artificial intelligence tools for chronic pulmonary embolism on CT pulmonary angiography. Frontiers in Radiology, 4, 1335349.
- Comparison of Contemporary Risk Scores in All Groups of Pulmonary Hypertension. CHEST.
- Pulmonary Hypertension: Intensification and Personalization of Combination Rx (PHoenix): A phase IV randomized trial for the evaluation of dose‐response and clinical efficacy of riociguat and selexipag using implanted technologies. Pulmonary Circulation, 14(1).
- Improving Prognostication in Pulmonary Hypertension Using AI-quantified Fibrosis and Radiologic Severity Scoring at Baseline CT. Radiology, 310(2).
- Effect of macitentan in pulmonary arterial hypertension and the relationship between echocardiography and cMRI variables: REPAIR echocardiography sub-study results. Cardiology and Therapy. View this article in WRRO
- Comparison of cardiac magnetic resonance imaging, functional and haemodynamic variables in pulmonary arterial hypertension: insights from REPAIR. ERJ Open Research, 10(1), 00547-2023.
- Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension. Nature Communications, 15(1). View this article in WRRO
- Risk assessment and real-world outcomes in chronic thromboembolic pulmonary hypertension: insights from a UK pulmonary hypertension referral service. BMJ Open, 14(1), e080068-e080068.
- Abstract 13918: Improvement of Pulmonary Arterial Hypertension (PAH) Risk Assessment Model Using Cardiac Magnetic Resonance Imaging Variables. Circulation, 148(Suppl_1).
- Multicenter standardization of phase-resolved functional lung MRI in patients with suspected chronic thromboembolic pulmonary hypertension. Journal of Magnetic Resonance Imaging. View this article in WRRO
- Pulmonary hypertension associated with lung disease: new insights into pathomechanisms, diagnosis, and management. The Lancet Respiratory Medicine, 11(9), 820-835.
- Defining the clinical validity of genes reported to cause pulmonary arterial hypertension. Genetics in Medicine, 25(11), 100925-100925.
- Assessment of Right Ventricular Function—a State of the Art. Current Heart Failure Reports, 20(3), 194-207.
- Non-invasive detection of severe PH in lung disease using magnetic resonance imaging. Frontiers in Cardiovascular Medicine, 10.
- 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Giornale italiano di cardiologia (2006), 24(4), 1e-116e.
- Pulmonary Artery Strain Predicts Prognosis in Pulmonary Arterial Hypertension. JACC: Cardiovascular Imaging.
- A transparent artificial intelligence framework to assess lung disease in pulmonary hypertension. Scientific Reports, 13.
- Corrigendum to: 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS). Endorsed by the International Society for Heart and Lung Transplantation (ISHLT) and the European Reference Network on rare respiratory diseases (ERN-LUNG). European Heart Journal, 44(15), 1312-1312.
- Semi-automatic thresholding of RV trabeculation improves repeatability and diagnostic value in suspected pulmonary hypertension. Frontiers in Cardiovascular Medicine, 9.
- Genetic counselling and testing in pulmonary arterial hypertension: a consensus statement on behalf of the International Consortium for Genetic Studies in PAH. European Respiratory Journal, 61(2), 2201471-2201471.
- 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Respiratory Journal, 61(1), 2200879-2200879.
- Abstract 14089: CT Analysis of Small Pulmonary Vessels and Its Association With Pulmonary Function Tests and Prognosis in Pulmonary Hypertension. Circulation, 146(Suppl_1).
- Phenotypes of idiopathic pulmonary arterial hypertension – Authors' reply. The Lancet Respiratory Medicine, 10(10), e90-e91.
- Healthcare resource utilization and quality of life in patients with sarcoidosis‐associated pulmonary hypertension. Pulmonary Circulation, 12(4).
- Atrial flutter and fibrillation in patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension in the ASPIRE registry: Comparison of rate versus rhythm control approaches. International Journal of Cardiology.
- Validation of Artificial Intelligence Cardiac MRI Measurements: Relationship to Heart Catheterization and Mortality Prediction. Radiology, 304(3), E56-E56.
- 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Heart Journal, 43(38), 3618-3731.
- Pulmonary Vascular Research Institute GoDeep: a meta-registry merging deep phenotyping datafrom international PH reference centers. Pulmonary Circulation, 12(3). View this article in WRRO
- Correction to: Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension. BMC Pulmonary Medicine, 22(1).
- First genotype-phenotype study in TBX4 syndrome : gain-of-function mutations causative for lung disease. American Journal of Respiratory and Critical Care Medicine.
- Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 206(1), 81-93.
- Phenotyping of idiopathic pulmonary arterial hypertension : a registry analysis. The Lancet Respiratory Medicine. View this article in WRRO
- Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 205(12), 1449-1460.
- Validation of Artificial Intelligence Cardiac MRI Measurements: Relationship to Heart Catheterization and Mortality Prediction.. Radiology, 212929.
- Right ventricular remodelling in pulmonary arterial hypertension predicts treatment response.. Heart. View this article in WRRO
- Cardiac magnetic resonance identifies raised left ventricular filling pressure: prognostic implications. European Heart Journal. View this article in WRRO
- Machine learning cardiac-MRI features predict mortality in newly diagnosed pulmonary arterial hypertension. European Heart Journal - Digital Health, 3(2), 265-275.
- Haematopoietic stem cell transplantation for severe autoimmune diseases in children : a review of current literature, registry activity and future directions on behalf of the autoimmune diseases and paediatric diseases working parties of the European Society for Blood and Marrow Transplantation. British Journal of Haematology, 198(1), 24-45.
- Examining the impact of pulmonary hypertension on nonprofessional caregivers: A mixed‐methods systematic review. Pulmonary Circulation, 12(2).
- Training and clinical testing of artificial intelligence derived right atrial cardiovascular magnetic resonance measurements. Journal of Cardiovascular Magnetic Resonance, 24(1).
- Imaging and risk stratification in pulmonary arterial hypertension : time to include right ventricular assessment. Frontiers in Cardiovascular Medicine, 9. View this article in WRRO
- Positive Predictors for Response to Ambrisentan Combination Therapy in Pulmonary Arterial Hypertension. International Heart Journal, 63(1), 99-105.
- Computed tomography lung parenchymal descriptions in routine radiological reporting have diagnostic and prognostic utility in patients with idiopathic pulmonary arterial hypertension and pulmonary hypertension associated with lung disease.. ERJ Open Res, 8(1).
- Supplementation with Iron in Pulmonary Arterial Hypertension: Two Randomized Crossover Trials (vol 18, pg 981, 2021). ANNALS OF THE AMERICAN THORACIC SOCIETY, 19(4), 703-703.
- Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood. Nature Communications, 12. View this article in WRRO
- The REPAIR Study : effects of macitentan on RV structure and function in pulmonary arterial hypertension. JACC: Cardiovascular Imaging.
- Repeatability and sensitivity to change of non-invasive end points in PAH: the RESPIRE study. Thorax, 76(10), 1032-1035.
- Positioning imatinib for pulmonary arterial hypertension: A phase I/II design comprising dose finding and single-arm efficacy. Pulmonary Circulation, 11(4). View this article in WRRO
- Mendelian randomisation and experimental medicine approaches to IL-6 as a drug target in PAH.. Eur Respir J.
- Pulmonary hypertension phenotypes in patients with systemic sclerosis. European Respiratory Review, 30(161), 210053-210053.
- Assessing pulmonary hypertension severity in lung disease is a key step to improving outcomes: embrace resistance and don't be pressurised to go with the flow. European Respiratory Journal, 58(2), 2102008-2102008.
- High interstudy repeatability of automatic deep learnt biventricular CMR measurements. European Heart Journal - Cardiovascular Imaging, 22(Supplement_2).
- Fully automated CMR derived stroke volume correlates with right heart catheter measurements in patients with suspected pulmonary hypertension. European Heart Journal - Cardiovascular Imaging, 22(Supplement_2).
- A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach. EBioMedicine, 69. View this article in WRRO
- Current strategies for managing chronic thromboembolic pulmonary hypertension: results of the worldwide prospective CTEPH Registry. ERJ Open Research, 7(3), 00850-2020.
- Right ventricular adaptation assessed using cardiac magnetic resonance predicts survival in pulmonary arterial hypertension. JACC: Cardiovascular Imaging, 14(6), 1271-1272. View this article in WRRO
- Cardiovascular magnetic resonance predicts all-cause mortality in pulmonary hypertension associated with heart failure with preserved ejection fraction. International Journal of Cardiovascular Imaging. View this article in WRRO
- Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. Genome Medicine, 13(1), 80-80. View this article in WRRO
- Outcomes following emergency fixation of torted and non-torted testes. Journal of Pediatric Urology.
- COMPARISON OF STANDARDIZED TREATMENT EFFECT SIZES FOR INVASIVE AND NON-INVASIVE ENDPOINTS IN PULMONARY ARTERIAL HYPERTENSION: INSIGHTS FROM THE REPAIR STUDY. Journal of the American College of Cardiology, 77(18), 1672-1672.
- Pulmonary hypertension in association with lung disease : quantitative CT and artificial intelligence to the rescue? State-of-the-art review. Diagnostics, 11(4). View this article in WRRO
- Correction. JACC: Cardiovascular Imaging, 14(4), 884-884.
- Supplementation with iron in pulmonary arterial hypertension : two randomized crossover trials. Annals of the American Thoracic Society.
- Myocardial T1-mapping and extracellular volume in pulmonary arterial hypertension: A systematic review and meta-analysis. Magnetic Resonance Imaging, 79, 66-75.
- Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement. British Journal of Anaesthesia.
- A machine learning cardiac magnetic resonance approach to extract disease features and automate pulmonary arterial hypertension diagnosis. European Heart Journal - Cardiovascular Imaging, 22(2), 236-245. View this article in WRRO
- Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension. Circulation: Genomic and Precision Medicine, 14(1), 57-70. View this article in WRRO
- Current and future treatments of pulmonary arterial hypertension. British Journal of Pharmacology, 178(1), 6-30. View this article in WRRO
- Cardiac Magnetic Resonance in Pulmonary Hypertension—an Update. Current Cardiovascular Imaging Reports, 13(12).
- Adults’ experiences of living with pulmonary hypertension: a thematic synthesis of qualitative studies. BMJ Open, 10(12). View this article in WRRO
- Mild parenchymal lung disease is still lung disease. The European respiratory journal, 56(5).
- Effect of macitentan on left ventricular (LV) function in pulmonary arterial hypertension (PAH): results from REPAIR. European Heart Journal, 41(Supplement_2).
- Cardiac-MRI predicts clinical worsening and mortality in pulmonary arterial hypertension: a systematic review and meta-analysis. JACC: Cardiovascular Imaging. View this article in WRRO
- Maximal exercise testing using the incremental shuttle walking test can be used to risk stratify patients with pulmonary arterial hypertension. Annals of the American Thoracic Society. View this article in WRRO
- Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension. European Radiology, 30(9), 4918-4929. View this article in WRRO
- Deprivation and prognosis in patients with pulmonary arterial hypertension: missing the effect of deprivation on a rare disease?. European Respiratory Journal, 56(2).
- Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension. Circulation, 142(15), 1464-1484.
- Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature, 584(7819), E2-E2.
- EmPHasis-10 health-related quality of life score predicts outcomes in patients with idiopathic and connective tissue disease-associated pulmonary arterial hypertension: results from a UK multi-centre study. European Respiratory Journal. View this article in WRRO
- BNP/NT-proBNP in pulmonary arterial hypertension: time for point-of-care testing?. European Respiratory Review, 29(156). View this article in WRRO
- Age-associated changes in 4D flow CMR derived tricuspid valvular flow and right ventricular blood flow kinetic energy. Scientific Reports, 10(1). View this article in WRRO
- Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension. European Respiratory Journal, 55(6). View this article in WRRO
- Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature. View this article in WRRO
- Whole blood RNA profiles associated with pulmonary arterial hypertension and clinical outcome. American Journal of Respiratory and Critical Care Medicine. View this article in WRRO
- Intravascular ultrasound pulmonary artery denervation to treat pulmonary arterial hypertension (TROPHY1): multicenter, early feasibility study. JACC: Cardiovascular Interventions, 13(8), 989-999. View this article in WRRO
- Comparison of MRI and VQ-SPECT as a Screening Test for Patients With Suspected CTEPH: CHANGE-MRI Study Design and Rationale. Frontiers in Cardiovascular Medicine, 7. View this article in WRRO
- Partial anomalous pulmonary venous drainage in patients presenting with suspected pulmonary hypertension: A series of 90 patients from the ASPIRE registry. Respirology. View this article in WRRO
- Results from the REPAIR Study Final Analysis: Effects of Macitentan on Right Ventricular (RV) Remodelling in Pulmonary Arterial Hypertension (PAH). The Journal of Heart and Lung Transplantation, 39(4), S16-S17.
- Combination therapy with oral treprostinil for pulmonary arterial hypertension. A double-blind placebo-controlled clinical trial. American Journal of Respiratory and Critical Care Medicine, 201(6), 707-717. View this article in WRRO
- Idiopathic pulmonary arterial hypertension and co-existing lung disease: is this a new phenotype?. Pulmonary Circulation, 10(1), 204589402091485-204589402091485.
- Identification of Cardiac Magnetic Resonance Imaging Thresholds for Risk Stratification in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 201(4), 458-468. View this article in WRRO
- Whole-genome sequencing of patients with rare diseases in a national health system. Nature, 583(7814), 96-102.
- Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 201(5), 575-585.
- A multicenter study of anticoagulation in operable chronic thromboembolic pulmonary hypertension. Journal of Thrombosis and Haemostasis, 18(1), 114-122.
- Screening strategies for pulmonary arterial hypertension. European Heart Journal Supplements, 21(Supplement_K), K9-K20. View this article in WRRO
- The patient experience of pulmonary hypertension : a large cross-sectional study of UK patients. BMC Pulmonary Medicine, 19(1). View this article in WRRO
- A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension. Nature Communications, 10(1). View this article in WRRO
- Utilising artificial intelligence to determine patients at risk of a rare disease : idiopathic pulmonary arterial hypertension. Pulmonary Circulation, 9(4). View this article in WRRO
- Exploring a physiotherapy well-being review to deliver community-based rehabilitation in patients with pulmonary hypertension. Pulmonary Circulation, 9(4). View this article in WRRO
- IodiNe Subtraction mapping in the diagnosis of Pulmonary chronIc thRomboEmbolic disease (INSPIRE) : rationale and methodology of a cross-sectional observational diagnostic study. Contemporary Clinical Trials Communications, 15. View this article in WRRO
- Arrhythmic burden and outcomes in pulmonary arterial hypertension. Frontiers in Medicine, 6. View this article in WRRO
- EXPRESS: Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI).. Pulmonary Circulation, 9(3). View this article in WRRO
- Germline selection shapes human mitochondrial DNA diversity. Science, 364(6442), eaau6520-eaau6520.
- Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia. The American Journal of Human Genetics, 104(5), 948-956.
- The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry. Pulmonary Circulation, 9(2). View this article in WRRO
- Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: A United Kingdom cohort study analysis.. European Respiratory Journal. View this article in WRRO
- A Systematic Review of Right Ventricular Diastolic Assessment by 4D Flow CMR. BioMed Research International, 2019. View this article in WRRO
- Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. The Lancet Respiratory Medicine, 7(3), 227-238. View this article in WRRO
- Decision-making in pulmonary endarterectomy surgery. European Respiratory Journal, 53(1), 1801973-1801973.
- ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension. European Respiratory Journal, 53(2), 1800332-1800332.
- Diagnostic and prognostic significance of cardiovascular magnetic resonance native myocardial T1 mapping in patients with pulmonary hypertension. Journal of Cardiovascular Magnetic Resonance, 20. View this article in WRRO
- Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data. Scientific Reports, 8(1). View this article in WRRO
- Diagnosis of Pulmonary Hypertension with Cardiac MRI: Derivation and Validation of Regression Models.. Radiology, 290(1). View this article in WRRO
- Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension. Circulation. Genomic and precision medicine, 11(10). View this article in WRRO
- Identifying At-Risk Patients with Combined Pre- and Postcapillary Pulmonary Hypertension Using Interventricular Septal Angle at Cardiac MRI. Radiology, 289(1), 180120-180120. View this article in WRRO
- The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension. European Respiratory Journal, 52(3), ---. View this article in WRRO
- High levels of healthcare utilization prior to diagnosis in idiopathic pulmonary arterial hypertension support the feasibility of an early diagnosis algorithm: the SPHInX project.. Pulmonary Circulation, 8(4), 1-9. View this article in WRRO
- Novel imaging techniques in pulmonary hypertension. Current Opinion in Cardiology, 33(6), 587-593.
- Autologous haematopoietic stem cell transplantation (aHSCT) for severe resistant autoimmune and inflammatory diseases – a guide for the generalist. Clinical Medicine, 18(4), 329-334. View this article in WRRO
- De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures. The American Journal of Human Genetics, 103(1), 144-153. View this article in WRRO
- Comprehensive cancer-predisposition gene testing in an adult multiple primary tumor series shows a broad range of deleterious variants and atypical tumor phenotypes. The American Journal of Human Genetics, 103(1), 3-18. View this article in WRRO
- Reversible pulmonary artery perfusion abnormalities in the postpartum period as a precursor to the development of pulmonary arterial hypertension. Pulmonary Circulation, 8(3). View this article in WRRO
- Pulmonary Artery Size in Interstitial Lung Disease and Pulmonary Hypertension: Association with Interstitial Lung Disease Severity and Diagnostic Utility. Frontiers in Cardiovascular Medicine, 5. View this article in WRRO
- Pathophysiology and diagnosis of pulmonary hypertension due to left heart disease. Frontiers in Medicine, 5. View this article in WRRO
- CT derived left atrial size identifies left heart disease in suspected pulmonary hypertension: Derivation and validation of predictive thresholds. International Journal of Cardiology, 260, 172-177. View this article in WRRO
- Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. Nature Communications, 9(1). View this article in WRRO
- i069 Assessment and management of pulmonary vascular manifestations of systemic sclerosis. Rheumatology, 57(suppl_3).
- i091 When to screen patients for pulmonary hypertension and interpreting the results. Rheumatology, 57(suppl_3).
- Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension. BMC Pulmonary Medicine, 18(1). View this article in WRRO
- Current and emerging imaging techniques in the diagnosis and assessment of pulmonary hypertension. Expert Review of Respiratory Medicine, 12(2), 145-160. View this article in WRRO
- Symptom severity and its effect on health-related quality of life over time in patients with pulmonary hypertension: a multisite longitudinal cohort study. BMJ Open Respiratory Research, 5(1), e000263-e000263. View this article in WRRO
- Pulmonary arteriovenous malformations emerge from the shadows. Thorax, 72(12), 1071-1073.
- British Thoracic Society Clinical Statement on Pulmonary Arteriovenous Malformations. Thorax, 72(12), 1154-1163.
- Phenotypic Characterisation of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically with Pulmonary Arterial Hypertension.. Circulation, 136(21), 2022-2033. View this article in WRRO
- Lung perfusion: MRI vs. SPECT for screening in suspected chronic thromboembolic pulmonary hypertension. Journal of Magnetic Resonance Imaging, 46(6), 1693-1697. View this article in WRRO
- Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients.. Sci Transl Med, 9(413).
- A social‐technological epistemology of clinical decision‐making as mediated by imaging. Journal of Evaluation in Clinical Practice, 23(5), 949-958. View this article in WRRO
- The CRASH report: emergency management dilemmas facing acute physicians in patients with pulmonary arterial hypertension. Thorax, 72(11), 1035-1045.
- Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study. The Lancet Respiratory Medicine, 5(9), 717-726. View this article in WRRO
- Septal angle on MRI predicts combined pre- and post-capillary pulmonary hypertension. Clinical Radiology, 72, S1-S2.
- Magnetic Resonance Imaging in the Prognostic Evaluation of Patients with Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 196(2). View this article in WRRO
- Critical care management of pulmonary hypertension. BJA Education, 17(7), 228-234.
- Specific Alleles of CLN7/MFSD8, a Protein That Localizes to Photoreceptor Synaptic Terminals, Cause a Spectrum of Nonsyndromic Retinal Dystrophy. Investigative Opthalmology & Visual Science, 58(7), 2906-2906.
- Combining creative writing and narrative analysis to deliver new insights into the impact of pulmonary hypertension. BMJ Open Respiratory Research, 4(1). View this article in WRRO
- Cardiopulmonary assessment of patients with systemic sclerosis for hematopoietic stem cell transplantation: recommendations from the European Society for Blood and Marrow Transplantation Autoimmune Diseases Working Party and collaborating partners.. Bone Marrow Transplantation. View this article in WRRO
- Incremental Shuttle Walking Test Distance and Autonomic Dysfunction Predict Survival in Pulmonary Arterial Hypertension. The Journal of Heart and Lung Transplantation. View this article in WRRO
- P-131 Meeting the needs of patients with pulmonary arterial hypertension: an important role for a hospital palliative care team. BMJ Supportive & Palliative Care, 7(Suppl 1), A48.3-A49.
- Idiopathic and Systemic Sclerosis associated Pulmonary Arterial Hypertension: A Comparison of Demographic, Haemodynamic and Magnetic Resonance Imaging Characteristics and Outcomes.. Chest.
- Biallelic Mutation of ARHGEF18 , Involved in the Determination of Epithelial Apicobasal Polarity, Causes Adult-Onset Retinal Degeneration. The American Journal of Human Genetics, 100(2), 334-342.
- Plasma Metabolomics Implicate Modified Transfer RNAs and Altered Bioenergetics in the Outcome of Pulmonary Arterial Hypertension.. Circulation, 135, 460-475. View this article in WRRO
- Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease. The American Journal of Human Genetics, 100(1), 75-90.
- Survival in portopulmonary hypertension: Outcomes of the united kingdom national pulmonary arterial hypertension registry. The Journal of Heart and Lung Transplantation.
- Bosutinib therapy resulting in severe deterioration of pre-existing pulmonary arterial hypertension. European Respiratory Journal, 48(5), 1514-1514.
- Long-term outcomes of domiciliary intravenous iloprost in idiopathic and connective tissue disease-associated pulmonary arterial hypertension.. Respirology.
- Diagnosis of Pulmonary Hypertension from Magnetic Resonance Imaging–Based Computational Models and Decision Tree Analysis. Pulmonary Circulation, 6(2), 181-190. View this article in WRRO
- Dynamic Risk Stratification of Patient Long-Term Outcome After Pulmonary Endarterectomy: Results From the United Kingdom National Cohort. Circulation, 133(18), 1761-1771.
- Breathlessness in an ex-miner: an unusual consideration. Thorax, 71(5), 481-482.
- Pulmonary Hypertension in Patients with Heart Failure and Preserved Ejection Fraction: Differential Diagnosis and Management. Pulmonary Circulation, 6(1), 3-14.
- Guía ESC/ERS 2015 sobre diagnóstico y tratamiento de la hipertensión pulmonar. Revista Española de Cardiología, 69(2), 177.e1-177.e62.
- Pulmonary arterial hypertension associated with congenital heart disease: Comparison of clinical and anatomic–pathophysiologic classification. The Journal of Heart and Lung Transplantation, 35(5), 610-618. View this article in WRRO
- 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Heart Journal, 37(1), 67-119.
- Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension. Current Cardiovascular Imaging Reports, 8(12).
- Pulmonary Artery Denervation Reduces Pulmonary Artery Pressure and Induces Histological Changes in an Acute Porcine Model of Pulmonary Hypertension. Circulation: Cardiovascular Interventions, 8(11), e002569-e002569. View this article in WRRO
- Management of acute pulmonary embolism. British Journal of Hospital Medicine, 76(10), C150-C155.
- Statement on Pregnancy in Pulmonary Hypertension from the Pulmonary Vascular Research Institute. Pulmonary Circulation, 5(3), 435-465.
- Longitudinal and Transverse Right Ventricular Function in Pulmonary Hypertension: Cardiovascular Magnetic Resonance Imaging Study from the ASPIRE Registry. Pulmonary Circulation, 5(3), 557-564.
- Experimental validation of the hyperpolarized 129 Xe chemical shift saturation recovery technique in healthy volunteers and subjects with interstitial lung disease. Magnetic Resonance in Medicine, 74(1), 196-207. View this article in WRRO
- Right Ventricular Sex Differences in Patients with Idiopathic Pulmonary Arterial Hypertension Characterised by Magnetic Resonance Imaging: Pair-Matched Case Controlled Study. PLOS ONE, 10(5), e0127415-e0127415. View this article in WRRO
- CT features of pulmonary arterial hypertension and its major subtypes: a systematic CT evaluation of 292 patients from the ASPIRE Registry. Thorax, 70(4), 382-387. View this article in WRRO
- Triage for suspected acute Pulmonary Embolism: Think before opening Pandora's Box. European Journal of Radiology, 84(6), 1202-1211.
- LGE Patterns in Pulmonary Hypertension Do Not Impact Overall Mortality. JACC: Cardiovascular Imaging, 7(12), 1209-1217.
- MRI model-based non-invasive differential diagnosis in pulmonary hypertension. Journal of Biomechanics, 47(12), 2941-2947. View this article in WRRO
- Magnetic Resonance Imaging of Ventilation and Perfusion Changes in Response to Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine, 190(5), e18-e19. View this article in WRRO
- Ambrisentan therapy in pulmonary hypertension: clinical use and tolerability in a referral centre.. Ther Adv Respir Dis, 8(3), 71-77.
- emPHasis-10: development of a health-related quality of life measure in pulmonary hypertension.. European Respiratory Journal, 43, 1106-1113. View this article in WRRO
- Dynamic contrast-enhanced magnetic resonance imaging in patients with pulmonary arterial hypertension.. Pulm Circ, 4(1), 61-70. View this article in WRRO
- Quantitative magnetic resonance imaging of pulmonary hypertension: a practical approach to the current state of the art.. J Thorac Imaging, 29(2), 68-79.
- Management dilemmas in acute pulmonary embolism.. Thorax, 69(2), 174-180. View this article in WRRO
- Prognostic value of cardiovascular magnetic resonance imaging measurements corrected for age and sex in idiopathic pulmonary arterial hypertension.. Circ Cardiovasc Imaging, 7(1), 100-106.
- Prognostic value of right ventricular function in patients with severe pulmonary hypertension associated with respiratory disease. EUROPEAN RESPIRATORY JOURNAL, 42.
- Prognostic predictors in younger and older incident idiopathic pulmonary arterial hypertension. EUROPEAN RESPIRATORY JOURNAL, 42.
- Pulmonary hypertension associated with congenital heart disease (PH-CHD): Results from the ASPIRE registry. EUROPEAN RESPIRATORY JOURNAL, 42.
- Primary pulmonary artery sarcoma and coexisting chronic thromboembolic pulmonary hypertension.. Am J Respir Crit Care Med, 188(5), e7-e8.
- Oral treprostinil for the treatment of pulmonary arterial hypertension in patients receiving background endothelin receptor antagonist and phosphodiesterase type 5 inhibitor therapy (The FREEDOM-C2 Study): A randomized controlled trial. Chest, 144(3), 952-958.
- Pregnancy and pulmonary hypertension: a practical approach to management.. Obstetric Medicine(6), 144-154.
- Noninvasive estimation of PA pressure, flow, and resistance with CMR imaging: derivation and prospective validation study from the ASPIRE registry.. JACC Cardiovasc Imaging, 6(10), 1036-1047.
- Pulmonary hypertension in COPD: results from the ASPIRE registry.. Eur Respir J, 41(6), 1292-1301.
- Central venous catheter-related blood stream infections in patients receiving intravenous iloprost for pulmonary hypertension.. Eur J Clin Microbiol Infect Dis, 32(7), 883-889.
- Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension.. Am J Respir Crit Care Med, 187(3), 294-302.
- Improving safety in autologous HSCT for systemic sclerosis.. Lancet, 381(9872), 1081-1083.
- Longitudinal And Transverse Right Ventricular Function In Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187.
- CT Features Of Pulmonary Arterial Hypertension And Its Major Subtypes: A Study Of 292 Patients. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187.
- Supplementation of iron in pulmonary hypertension: Rationale and design of a phase II clinical trial in idiopathic pulmonary arterial hypertension.. Pulmonary Circulation, 1(3), 100-107.
- Supplementation of Iron in Pulmonary Hypertension: Rationale and Design of a Phase II Clinical Trial in Idiopathic Pulmonary Arterial Hypertension. Pulmonary Circulation, 3(1), 100-107.
- Pulmonary hypertension: diagnosis and management.. BMJ, 346, f2028.
- Pulmonary hypertension in renal disease: epidemiology, potential mechanisms and implications.. Am J Nephrol, 37(3), 281-290.
- Changing demographics, epidemiology, and survival of incident pulmonary arterial hypertension: results from the pulmonary hypertension registry of the United Kingdom and Ireland.. Am J Respir Crit Care Med, 186(8), 790-796.
- Inhibition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension.. J Exp Med, 209(11), 1919-1935. View this article in WRRO
- Treat-to-target approach in pulmonary arterial hypertension: a consensus-based proposal.. Eur Respir Rev, 21(125), 259-262.
- Diagnostic accuracy of cardiovascular magnetic resonance imaging of right ventricular morphology and function in the assessment of suspected pulmonary hypertension results from the ASPIRE registry.. J Cardiovasc Magn Reson, 14, 40. View this article in WRRO
- Comparison of the diagnostic utility of cardiac magnetic resonance imaging, computed tomography, and echocardiography in assessment of suspected pulmonary arterial hypertension in patients with connective tissue disease.. J Rheumatol, 39(6), 1265-1274.
- ASPIRE registry: assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre.. Eur Respir J, 39(4), 945-955.
- Lung morphology assessment with balanced steady-state free precession MR imaging compared with CT.. Radiology, 263(2), 569-577.
- Serum osteoprotegerin is increased and predicts survival in idiopathic pulmonary arterial hypertension.. Pulm Circ, 2(1), 21-27. View this article in WRRO
- Black blood MRI has diagnostic and prognostic value in the assessment of patients with pulmonary hypertension.. Eur Radiol, 22(3), 695-702.
- Diagnostic accuracy of contrast-enhanced MR angiography and unenhanced proton MR imaging compared with CT pulmonary angiography in chronic thromboembolic pulmonary hypertension.. Eur Radiol, 22(2), 310-317.
- Improved Survival in Pregnancy and Pulmonary Hypertension Using a Multiprofessional Approach. Obstetric Anesthesia Digest, 31(2), 122-122.
- Survival in Pulmonary Hypertension Registries The Importance of Incident Cases. CHEST, 139(6), 1547-1548.
- CT pulmonary angiography combined with echocardiography in suspected systemic sclerosis-associated pulmonary arterial hypertension.. Rheumatology (Oxford), 50(8), 1480-1486.
- Critical care outcome of pulmonary artery hypertension. Critical Care, 15(Suppl 1), P494-P494.
- Survival Of Incident Cases Of Idiopathic, Heritable And Anorexigen-Associated Pulmonary Arterial Hypertension. Results From Pulmonary Hypertension Registry Of The United Kingdom And Ireland (Proud Registry). D34. PULMONARY HYPERTENSION: ENDPOINTS AND OUTCOMES.
- CT Pulmonary Angiography Combined With Echocardiography In Suspected Systemic Sclerosis-Associated Pulmonary Arterial Hypertension. A60. PULMONARY HYPERTENSION: DIAGNOSIS.
- Black blood MRI has diagnostic and prognostic value in the assessment of patients with pulmonary hypertension. European Radiology, 1-8.
- Paigen diet-fed apolipoprotein E knockout mice develop severe pulmonary hypertension in an interleukin-1-dependent manner.. Am J Pathol, 179(4), 1693-1705. View this article in WRRO
- Computed tomography and magnetic resonance imaging of pulmonary hypertension: Pulmonary vessels and right ventricle. Journal of Magnetic Resonance Imaging, 32(6), 1313-1324.
- Improved survival in pregnancy and pulmonary hypertension using a multiprofessional approach.. BJOG, 117(5), 565-574.
- PULMONARY FUNCTIONAL IMPAIRMENT WITH ISOLATED LOW TRANSFER FACTOR IN SYSTEMIC SCLEROSIS. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 28(2), S150-S151.
- Survival in Systemic Sclerosis-related Pulmonary Arterial Hypertension in the Modern Treatment Era. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 180(12), 1280-1281.
- Ventricular mass index correlates with pulmonary artery pressure and predicts survival in suspected systemic sclerosis-associated pulmonary arterial hypertension.. Rheumatology (Oxford), 48(9), 1137-1142.
- Prognostic and aetiological factors in chronic thromboembolic pulmonary hypertension. EUROPEAN RESPIRATORY JOURNAL, 33(2), 332-337.
- Connective tissue disease-associated pulmonary arterial hypertension in the modern treatment era.. Am J Respir Crit Care Med, 179(2), 151-157.
- Diagnosis and initial treatment of patients with suspected pulmonary thromboembolism. Continuing Education in Anaesthesia, Critical Care and Pain, 9(4), 119-124.
- Safety experience with bosentan in 146 children 2-11 years old with pulmonary arterial hypertension: Results from the European postmarketing surveillance program. PEDIATRIC RESEARCH, 64(2), 200-204.
- Improved outcomes in medically and surgically treated chronic thromboembolic pulmonary hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 177(10), 1122-1127.
- Consensus statement on the management of pulmonary hypertension in clinical practice in the UK and Ireland. Heart, 94(SUPPL. 1).
- Cavitating lung lesions in chronic thromboembolic pulmonary hypertension.. J Radiol Case Rep, 2(3), 11-21.
- Initial results of the united kingdom audit of pulmonary arterial hypertension associated with connective tissue disease (CTD-PAH). EUROPEAN HEART JOURNAL, 28, 139-140.
- Results of European post-marketing surveillance of bosentan in pulmonary hypertension. EUROPEAN RESPIRATORY JOURNAL, 30(2), 338-344.
- The role of vasopressin in cardiorespiratory arrest and pulmonary hypertension.. QJM, 99(3), 127-133.
- Combination of bosentan with prostanoids or sildenafil in pulmonary arterial hypertension was well tolerated: Results from the TRAX database. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 25(2), S75-S76.
- Pulmonary hypertension. Continuing Education in Anaesthesia, Critical Care and Pain, 6(1), 17-22.
- The use of iloprost in early pregnancy in patients with pulmonary arterial hypertension.. Eur Respir J, 26(1), 168-173.
- Decreased whole body endogenous nitric oxide production in patients with primary pulmonary hypertension.. J Vasc Res, 42(2), 133-136.
- Elevated levels of natriuretic peptides in patients with pulmonary thromboembolism. Respiratory Medicine, 99(10), 1286-1291.
- Pulmonary hypertension: diagnosis and treatment.. Clin Med (Lond), 4(3), 211-215.
- Histological evidence of pulmonary hypertension in normotensive but symptomatic patients. JOURNAL OF PATHOLOGY, 198, 47A-47A.
- Inhaled iloprost for severe pulmonary hypertension. NEW ENGL J MED, 347(5), 322-329.
- Clinical features of bacteraemia complicating IV prostaglandin therapy in patients with pulmonary hypertension. THORAX, 56, 78-78.
- Bedside tracer gas technique accurately predicts outcome in aspiration of spontaneous pneumothorax. THORAX, 56(8), 617-621.
- Latrogenic pneumothorax: Marker gas technique for predicting outcome of manual aspiration. RESPIRATION, 68(2), 165-168.
- Detection of loss of heterozygosity in plasma DNA of patients with lung cancer. Thorax, 55(SUPPL. 3).
- Bedside tracer gas technique accurately predicts outcome of spontaneous pneumothorax. THORAX, 55, A73-A73.
- Volume aspirated is an indicator of the success of manual aspiration in the treatment of spontaneous pneumothorax. THORAX, 55, A74-A74.
- Effects of acute oxygen therapy on left ventricular diastolic filling in hypoxaemic cor pulmonale. ACP-APPLIED CARDIOPULMONARY PATHOPHYSIOLOGY, 9(1), 27-31.
- The effect of nitric oxide inhibition on the renin response to frusemide, in man. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 48(3), 355-360.
- Predicting outcome of manual aspiration in the treatment of pneumothorax using a marker gas technique. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 159(3), A387-A387.
- Improved outcome from Chronic Obstructive Pulmonary Disease (COPD) exacerbations in a district general hospital following introduction of an oxygen prescription and guidance form. Thorax, 53(SUPPL. 4).
- Iatrogenic pneumothorax: Marker gas technique for predicting outcome of manual aspiration. Thorax, 53(SUPPL. 4).
- Nitric oxide: an important role in the maintenance of systemic and pulmonary vascular tone in man. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 46(3), 263-266.
- Use of pulsed-wave Doppler echocardiography to measure changes in MPAP - Is further validation required?. CHEST, 111(5), 1470-1470.
- Effects of frusemide and hypoxia on the pulmonary vascular bed in man. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 43(3), 309-313.
- Cardiopulmonary effects of endothelin-1 in man. CARDIOVASCULAR RESEARCH, 33(2), 378-386.
- Use of Pulsed-Wave Doppler Echocardiography to Measure Changes in MPAP. Chest, 111(5), 1469-1470.
- Haemodynamic and endocrine effects of type 1 angiotensin II receptor blockade in patients with hypoxaemic cor pulmonale. CARDIOVASCULAR RESEARCH, 33(1), 201-208.
- A role for natriuretic peptides in the diagnosis of pulmonary thromboembolism. Thorax, 51(SUPPL. 3).
- Angiotensin II receptor blockade and effects on pulmonary hemodynamics and hypoxic pulmonary vasoconstriction in humans. CHEST, 110(3), 698-703.
- Effects of hypercapnia on hemodynamic, inotropic, lusitropic, and electrophysiologic indices in humans. CHEST, 109(5), 1215-1221.
- Acute Hypoxic Pulmonary Vasoconstriction in Man is Attenuated by Type 1 Angiotensin II Receptor Blockade. Clinical Science, 90(s34), 5P-5P.
- Hypoxaemia and Release of Endothelin-1 in Humans. Clinical Science, 90(s34), 4P-5P.
- Systemic and Pulmonary Haemodynamic Effects of Endothelin-1 in Humans. Clinical Science, 90(s34), 4P-4P.
- HYPOXEMIA AND RELEASE OF ENDOTHELIN-1. THORAX, 50(12), 1308-1310.
- Acute hypoxic pulmonary vasoconstriction in man is attenuated by type I angiotensin II receptor blockade. CARDIOVASCULAR RESEARCH, 30(6), 875-880.
- ABNORMAL MYOCARDIAL REPOLARIZATION IN RESPONSE TO HYPOXEMIA AND FENOTEROL. THORAX, 50(10), 1062-1066.
- CARDIOPULMONARY INTERACTIONS OF SALBUTAMOL AND HYPOXEMIA IN HEALTHY-YOUNG VOLUNTEERS. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 40(4), 313-318.
- LEFT-VENTRICULAR SYSTOLIC PERFORMANCE DURING ACUTE HYPOXEMIA. CHEST, 108(4), 899-902.
- ADVERSE-EFFECTS OF HYPOXEMIA ON DIASTOLIC FILLING IN HUMANS. CLINICAL SCIENCE, 89(2), 165-169.
- Pre-Treatment with Frusemide Augments Hypoxic Pulmonary Vasoconstriction. Clinical Science, 89(s33), 28P-29P.
- HYPOXEMIA AND THE RENIN-ANGIOTENSIN SYSTEM - NEW ANSWERS FOR OLD QUESTIONS. PULMONARY PHARMACOLOGY, 7(5), 279-284.
- Worldwide CTEPH Registry: Long-Term Outcomes With Pulmonary Endarterectomy, Balloon Pulmonary Angioplasty, and Medical Therapy. Circulation.
- Emerging multimodality imaging techniques for the pulmonary circulation. European Respiratory Journal, 2401128-2401128.
- Unenhanced computed tomography as a diagnostic tool in suspected pulmonary hypertension: a retrospective cross-sectional pilot study. Wellcome Open Research, 6, 249-249.
- Initial combination therapy with macitentan and tadalafil in patients with pulmonary arterial hypertension, with and without cardiac comorbidities. European Journal of Heart Failure.
- Attitudes and barriers to pulmonary arterial hypertension screening in systemic sclerosis patients: A survey of UK-based rheumatologists. Journal of Scleroderma and Related Disorders.
- Systematic pulmonary embolism follow-up increases diagnostic rates of chronic thromboembolic pulmonary hypertension and identifies less severe disease: results from the ASPIRE Registry. European Respiratory Journal, 2300846-2300846.
- Pulmonary Embolism (PE) to Chronic Thromboembolic Pulmonary Disease (CTEPD): Findings from a Survey of UK Physicians. Advances in Respiratory Medicine, 92(1), 45-57.
- The Left Atrial Area Derived Cardiovascular Magnetic Resonance Left Ventricular Filling Pressure Equation Shows Superiority over Integrated Echocardiography. Medicina, 59(11), 1952-1952.
- Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. Nature Cardiovascular Research.
- Surgery and Anesthesia in Patients with Pulmonary Hypertension. Seminars in Respiratory and Critical Care Medicine.
- Predictors of outcomes in mild pulmonary hypertension according to 2022 ESC/ERS Guidelines: the EVIDENCE-PAH UK study. European Heart Journal.
- Establishing minimally important differences for cardiac MRI endpoints in pulmonary arterial hypertension. European Respiratory Journal, 2202225-2202225.
- Medical artificial intelligence is as much social as it is technological. Nature Machine Intelligence.
- Computational platform for doctor-AI cooperation in PAH prognostication: a pilot study. ERJ Open Research, 00484-2022.
- Pulmonary hypERtension and measurement of exerciSe caPacIty REmotely: evaluation of the 1-minute sit to stand test (PERSPIRE): a cohort study. ERJ Open Research, 00295-2022.
- Fully automatic cardiac four chamber and great vessel segmentation on CT pulmonary angiography using deep learning. Frontiers in Cardiovascular Medicine, 9.
- Vascular compression and pulmonary hypertension: the occupational context. Occupational and Environmental Medicine.
- GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements. Nature Communications, 13(1).
- Quantitative CT Evaluation of Small Pulmonary Vessels Has Functional and Prognostic Value in Pulmonary Hypertension. Radiology.
- Severe pulmonary hypertension associated with lung disease is characterised by a loss of small pulmonary vessels on quantitative CT. ERJ Open Research, 00503-2021.
- CMR Measures of Left Atrial Volume Index and Right Ventricular Function Have Prognostic Value in Chronic Thromboembolic Pulmonary Hypertension. Frontiers in Medicine, 9.
- Comment on “External validation of the OPALS prediction model for in-hospital mortality in patients with acute decompensated pulmonary hypertension”. ERJ Open Research, 00066-2022.
- Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine.
- Elective lower limb orthopaedic arthroplasty surgery in patients with pulmonary hypertension. Pulmonary Circulation.
- Hematopoietic stem cell transplantation in autoimmune diseases: update from EBMT Autoimmune Diseases Working Party with special reference to Poland. Acta Haematologica Polonica, 52(4), 217-224.
- Establishing expert consensus for the optimal approach to holistic risk-management in pulmonary arterial hypertension: a Delphi process and narrative review. Expert Review of Respiratory Medicine, 1-11.
- Feasibility and safety of a telemetric pulmonary artery pressure monitoring system in acute and chronic porcine models of pulmonary hypertension.
- Outcome Measures Used in Studies of Rehabilitation in Pulmonary Hypertension: A Systematic Review. Annals of the American Thoracic Society.
- Incremental Shuttle Walking Test Distance Is Reduced in Patients With Pulmonary Hypertension in World Health Organisation Functional Class I. Frontiers in Medicine, 5. View this article in WRRO
- Elevated Plasma CXCL12α Is Associated with a Poorer Prognosis in Pulmonary Arterial Hypertension. PLOS ONE, 10(4), e0123709-e0123709. View this article in WRRO
- Management of Suspected Chronic Thromboembolic Pulmonary Hypertension, 405-420.
- Critical care outcomes in patients with pre-existing pulmonary hypertension: insights from the ASPIRE registry. ERJ Open Research, 00046-2021.
- EXPRESS: Patterns of Thromboembolic Pulmonary Vascular Disease in COVID-19. Pulmonary Circulation, 204589402097919-204589402097919.
- Unenhanced computed tomography as a diagnostic tool in suspected pulmonary hypertension: a retrospective cross-sectional pilot study. Wellcome Open Research, 6, 249-249.
- Editorial : pulmonary hypertension : mechanisms and management, history and future. Frontiers in Medicine, 7. View this article in WRRO
- Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases : updated guidelines and recommendations from the EBMT autoimmune diseases working party (ADWP) and the joint accreditation committee of EBMT and ISCT (JACIE). Bone Marrow Transplantation. View this article in WRRO
- Integrated Cardiopulmonary MRI Assessment of Pulmonary Hypertension. Journal of Magnetic Resonance Imaging.
Chapters
- Systemic Sclerosis and the Lung, Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases (pp. 463-478). CRC Press
- Pulmonary Hypertension and Pregnancy, Respiratory Disease in Pregnancy (pp. 99-112). Cambridge University Press
- Pulmonary Hypertension and pregnancy In lapinski & plante (Ed.), Respiratory Disease in Pregnancy Cambridge University Press
- Pulmonary Hypertension, Foundations of Respiratory Medicine (pp. 315-330). Springer International Publishing
- Management of pulmonary hypertension in pregnancy In steer & gatzoulis (Ed.), Heart Disease and Pregnancy RCOG
- Deep Vein Thrombosis and Pulmonary Embolism In Beek EJRV, Büller HR & Oudkerk M (Ed.), Deep Vein Thrombosis and Pulmonary Embolism (pp. 405-420). Wiley
- Heart Disease and Pregnancy In Steer PJ, Gatzoulis MA & Baker P (Ed.), Heart Disease and Pregnancy (pp. 211-229). Rcog
- Management of pulmonary hypertension in pregnancy, Heart Disease and Pregnancy (pp. 144-159). Cambridge University Press
Conference proceedings papers
- Left ventricular diastolic dysfunction attenuates outcomes in CTEPH. Pulmonary hypertension
- Artificial Intelligence and Computed Tomography to improve quantification and prognostication of lung disease in precapillary pulmonary hypertension. Pulmonary hypertension
- An open-source tool for risk prediction in operable CTEPH. Pulmonary hypertension
- A real-word evidence study of PH-LD, PH-ILD and PAH in France, Germany, and the UK. Pulmonary hypertension
- P10 Defining cardiac MRI change thresholds based on how a patient feels, functions and survives post pulmonary arterial hypertension treatment. Scientific poster abstracts
- 196 The relationship of physical activity, heart rate variability, and night heart rate to established measures of clinical risk in patients with pulmonary arterial hypertension (pah). Stable IHD/Prevention/Hypertension/Lipids
- 158 Remote personalisation of pulmonary arterial hypertension therapy and application of a remote physiological risk score. Heart Failure
- 155 Effect of covid-19 infection and preventive public health measures on haemodynamics, activity and quality of life in patients with pulmonary arterial hypertension. Heart Failure
- 154 Stability of daily physical activity as a remote measure of clinical risk in pulmonary arterial hypertension (pah). Heart Failure
- 153 Differences in physical activity, heart rate and heart variability during clinical worsening events in patients with pulmonary arterial hypertension (pah). Heart Failure
- 138 Physiological detection of clinical worsening and therapeutic response using implanted remote technologies in pah. Heart Failure
- 137 Design and validation of a physiological risk score for pulmonary arterial hypertension (pah). Heart Failure
- Systematic Follow-up of Patients Following Acute Pulmonary Embolism Identifies High Incidence of Chronic Thromboembolic Pulmonary Hypertension: ASPIRE CTEPH. D106. HOT OFF THE PRESSES! LATE BREAKERS IN PULMONARY VASCULAR DISEASE
- Quantitative Computed Tomography Lung Parenchymal Features Can Aid in Phenotyping of Group 1 and Group 3 Pulmonary Hypertension. B60. LIFE MOVES FAST! LATE BREAKERS IN PULMONARY HYPERTENSION
- Assessing the Repeatability of NT-proBNP Testing Using Laboratory and Point of Care Testing in PAH (REPEAT-PAH). B57. INTERMEDIATES, CORRELATES, AND SURROGATES, OH MY!: NOVEL END POINTS AND ASSESSMENTS IN PVD
- 33 Cardiac MRI thresholds for improvement in pulmonary arterial hypertension. Abstracts
- The effect of parenchymal lung disease on patient characteristics and outcome in SSc-PH: Insights from the ASPIRE registry. 13.01 - Pulmonary hypertension
- Fully automatic deep learning pulmonary hypertension diagnosis using CT pulmonary angiography. 13.01 - Pulmonary hypertension
- Correlation of emPHasis-10 with clinical tests: insights from the ASPIRE registry. 13.01 - Pulmonary hypertension
- Prognostic importance of centrilobular ground glass changes in patients with Idiopathic Pulmonary Arterial Hypertension. 13.01 - Pulmonary hypertension
- New diagnostic criteria and PVR thresholds in SSc-associated PH: Insights from the ASPIRE registry. 13.01 - Pulmonary hypertension
- CMR assessed maladaptive right ventricular remodelling predicts treatment failure in pulmonary arterial hypertension. 13.01 - Pulmonary hypertension
- Pulmonary Hypertension and measurement of exercise capacity remotely: the PERSPIRE study. 01.05 - Clinical respiratory physiology, exercise and functional imaging
- Efficacy of oral treprostinil as an add-on therapy for PAH. 13.01 - Pulmonary hypertension
- S91 Remote monitored physical activity is related to established measures of clinical risk in patients with pulmonary arterial hypertension. ‘The Sixth Sense’ – Prognostication in pulmonary vascular disease
- P37 Correlation of emPHasis-10 with clinical tests: insights from the ASPIRE registry. ‘Mission (Im)possible I’ – Pulmonary vascular disease
- P81 Effect of COVID-19 infection and preventive public health measures on haemodynamics, activity and quality of life in patients with pulmonary arterial hypertension. ‘Contagion’ – The impact of COVID-19
- P38 Assessing the repeatability of NT-proBNP testing using laboratory and point of care testing in PAH (REPEAT-PAH). ‘Mission (Im)possible I’ – Pulmonary vascular disease
- S90 Right ventricular remodelling assessed using cardiac magnetic resonance predicts survival and treatment response in pulmonary arterial hypertension. Thorax, Vol. 77(Suppl 1) (pp a55-a56). Westminster, London, United Kingdom, 23 November 2022 - 23 November 2022. View this article in WRRO
- P39 Establishing minimally important differences for cardiac MRI endpoints in pulmonary arterial hypertension. Thorax, Vol. 77(Suppl 1) (pp A101-A102). Westminster, London, United Kingdom, 23 November 2022 - 23 November 2022. View this article in WRRO
- P41 CT lung parenchymal appearances in chronic thromboembolic pulmonary hypertension (CTEPH). ‘Mission (Im)possible I’ – Pulmonary vascular disease
- P42 Pulmonary embolism (PE) to chronic thromboembolic pulmonary disease (CTEPD): Findings from a survey of UK physicians. ‘Mission (Im)possible I’ – Pulmonary vascular disease
- S92 Remote monitoring enabled evaluation of risk and physiological response to therapeutic escalation and clinical worsening in patients with pulmonary hypertension. ‘The Sixth Sense’ – Prognostication in pulmonary vascular disease
- S93 Systematic follow-up of patients following acute pulmonary embolism is associated with an increased incidence of chronic thromboembolic pulmonary hypertension and less severe disease. Thorax, Vol. 77(Suppl 1) (pp a58-a59). Westminster, London, United Kingdom, 23 November 2022 - 23 November 2022. View this article in WRRO
- Abstract 13553: Remote Monitoring of the Haemodynamic Response to Clinically Indicated Therapeutic Escalation and Clinical Worsening Events in Patients With Pulmonary Arterial Hypertension. Circulation, Vol. 146(Suppl_1)
- Abstract 13527: The Development of a Remote Pulmonary Arterial Hypertension Risk Score Utilising Remote Monitoring Technology to Monitor Parameters Associated With Mortality in Pulmonary Arterial Hypertension. Circulation, Vol. 146(Suppl_1)
- Fully Automatic Cardiac and Great Vessel Segmentation on CT Pulmonary Angiography (CTPA) Using Deep Learning. D106. NOE VALLEY: CLOTS, COVID, AND LUNG VASCULAR DISEASES
- Training and clinical validation of artificial intelligence derived right atrial cardiovascular magnetic resonance measurements. American Journal of Respiratory and Critical Care Medicine, Vol. 205 (pp a2285-a2285). American Thoracic Society 2022 International Conference, 13 May 2022 - 13 May 2022. View this article in WRRO
- Deep Learning Approaches to Classify Lung Parenchymal Disease on CT Images. D106. NOE VALLEY: CLOTS, COVID, AND LUNG VASCULAR DISEASES
- Computed Tomography (CT) features are of diagnostic utility in pre diagnosis Idiopathic Pulmonary Arterial Hypertension (IPAH): a case controlled study. American Journal of Respiratory and Critical Care Medicine, Vol. 205 (pp a3605-a3605). San Francisco, CA, 13 May 2022 - 13 May 2022. View this article in WRRO
- Longitudinal Analysis of Three Major Risk-Associated Transcriptomic Subgroups Within the IPAH Classification. C55. NOB HILL: CELLULAR ORIGINS OF PULMONARY VASCULAR DISEASE
- CARE PAH study design: an international, prospective real-world cohort of PAH patients. EUROPEAN RESPIRATORY JOURNAL, Vol. 60
- Remote Monitoring of the Haemodynamic Response to Clinically Indicated Therapeutic Escalation and Clinical Worsening Events in Patients With Pulmonary Arterial Hypertension. CIRCULATION, Vol. 146
- The Development of a Remote Pulmonary Arterial Hypertension Risk Score Utilising Remote Monitoring Technology to Monitor Parameters Associated With Mortality in Pulmonary Arterial Hypertension. CIRCULATION, Vol. 146
- Efficacy and dose-response relationship of oral treprostinil in PAH patients on monotherapy or dual background therapy. EUROPEAN HEART JOURNAL, Vol. 43 (pp 1920-1920)
- Mortality rates and cause of mortality in patients with mildly elevated pulmonary pressures versus PH: insights from the retrospective EVIDENCE-PAH study. EUROPEAN HEART JOURNAL, Vol. 43 (pp 1927-1927)
- A fully automated cardiac magnetic resonance (CMR) assessment improves the evaluation of patients with pulmonary arterial hypertension (PAH). Imaging
- MRI metric lung parenchyma T1 indicates lung pathology in patients with pulmonary hypertension. Pulmonary hypertension
- Critical care outcomes in patients with pre-existing pulmonary hypertension: insights from the ASPIRE registry. Pulmonary hypertension
- The lived experiences of people shielding with pulmonary hypertension during the first wave of the COVID-19 pandemic. Pulmonary hypertension
- Abstract 13581: Heart Rhythm versus Heart Rate Control Strategy in Patients With Pre-Capillary Pulmonary Hypertension and Atrial Arrhythmias. Circulation, Vol. 144(Suppl_1)
- 19 Cardiac magnetic resonance to identify raised left ventricular filling pressure. Heart, Vol. 107(Suppl 3) (pp a17-a18). Virtual conference, 12 October 2021 - 12 October 2021. View this article in WRRO
- 124 Comparing the safety and feasibility of implanting pulmonary artery pressure monitors via the internal jugular vein compared to standard femoral venous access in patients with pulmonary arterial hypertension. Heart failure
- 121 Effect of UK COVID-19 public health measures on activity and quality of life in patients with pulmonary arterial hypertension. Heart failure
- S93 REPAIR: long-term effects of macitentan on the right ventricle (RV) in pulmonary arterial hypertension (PAH). Pulmonary arterial hypertension: drugs, sox and cytokines
- P140 Comparison of different measures of diffusion capacity in suspected systemic sclerosis associated pulmonary arterial hypertension. The nuts and bolts of ILD clinical management
- Heart Rhythm versus Heart Rate Control Strategy in Patients With Pre-Capillary Pulmonary Hypertension and Atrial Arrhythmias. CIRCULATION, Vol. 144
- Abstract 15636: Effect of COVID-19 Public Health Measures on Activity and Quality of Life in Patients With Pulmonary Arterial Hypertension. Circulation, Vol. 142(Suppl_3) View this article in WRRO
- Lung perfusion in pulmonary hypertension – results from the RESPIRE study. Pulmonary hypertension
- REPAIR: long-term effects of macitentan on the right ventricle (RV) in pulmonary arterial hypertension (PAH). Pulmonary hypertension
- Outcomes measures used in studies of exercise rehabilitation in pulmonary hypertension: a systematic review. Physiotherapists
- CIPHER: a prospective, multicentre study for the identification of biomarker signatures for early detection of pulmonary hypertension. Pulmonary hypertension
- Cardiac MRI right atrial area measurement thresholds for risk stratification in patients with PAH. Pulmonary hypertension
- Percent-predicted incremental shuttle walking test distance stratifies risk in pulmonary arterial hypertension. Pulmonary hypertension
- Sex bias exists in diagnosing pulmonary arterial hypertension via machine learning. Pulmonary hypertension
- EmPHasis-10 health-related quality of life score predicts outcomes in patients with idiopathic and connective tissue disease-associated pulmonary arterial hypertension: results from a UK multi-centre study. Pulmonary hypertension
- Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension. Pulmonary hypertension
- Cardiac MRI for Prognosis in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis. Imaging
- Serial cardiac MRI for assessment of cardiac morphology and function in CTEPH patients after PEA or vasodilator therapy. Pulmonary hypertension
- Perioperative management of patients with Pulmonary Hypertension undergoing Non-Cardiac Surgery: A Systemic Review and UK Consensus Statement. Pulmonary hypertension
- Multi-omic profiling in pulmonary arterial hypertension. Pulmonary hypertension
- Identification of Circulating Long Non-Coding RNA H19 as a Novel Biomarker for Right Ventricular Failure Associated with Pulmonary Arterial Hypertension. C105. WITH ALL MY HEART: SEX, ESTROGEN, AND RIGHT VENTRICLE IN PULMONARY VASCULAR DISEASE AND BEYOND
- Percutaneous Endovascular Ultrasound Pulmonary Artery Denervation for the Treatment of Pulmonary Arterial Hypertension: 12-Month Results of the Trophy 1 Study. D63. PULMONARY EMBOLISM: CASE REPORTS AND LATE BREAKING
- Long Non-Coding RNA H19 Promotes Right Ventricular Failure in PAH. A93. TRANSLATIONAL RESEARCH; EARLY CLINICAL FINDINGS AND OMICS ADVENTURE IN PULMONARY HYPERTENSION: FROM BIOMARKERS TO NEW THERAPEUTIC TARGETS
- P117 Machine learning tool provides new insights into risk assessment in pulmonary endarterectomy. Pulmonary hypertension: advances in diagnosis and treatment
- P119 Evolving surgical expertise and patient choice in pulmonary endarterectomy. Pulmonary hypertension: advances in diagnosis and treatment
- Late Breaking Abstract - Supplementation of iron in pulmonary hypertension (SIPHON): results from a randomised controlled crossover trial. Right ventricle
- P116 Effects of macitentan on right ventricular remodeling in pulmonary arterial hypertension – results from the REPAIR study interim analysis. Pulmonary hypertension: advances in diagnosis and treatment
- A prospective study comparing the repeatability and sensitivity to change of non-invasive endpoints in pulmonary arterial hypertension: the RESPIRE study. Pulmonary hypertension
- CT pulmonary angiography-derived right atrial area can risk stratify patients with PAH and PH. Imaging
- Repeatability and Sensitivity to change of right ventricular analysis methods using cardiac magnetic resonance imaging in PAH: results from the RESPIRE Study. Imaging
- Thoracic CT features of patients with BMPR2 mutation: preliminary analysis from the UK National Cohort Study of Idiopathic and Heritable PAH. Pulmonary hypertension
- Risk stratification of pulmonary arterial hypertension (PAH) associated with adult congenital heart disease (ACHD). Pulmonary hypertension
- Diagnostic and prognostic value of a diagnostic CT regression model in suspected pulmonary hypertension. Pulmonary hypertension
- Diagnostic accuracy of right ventricular trabecular mass measurements as measured on cardiac MRI in suspected pulmonary hypertension. Pulmonary hypertension
- 284An accurate, multi-parametric cardiovascular magnetic resonance model to predict mean pulmonary artery pressure in pulmonary hypertension. European Heart Journal - Cardiovascular Imaging, Vol. 20(Supplement_2) View this article in WRRO
- P165A novel cardiac magnetic resonance imaging model to predict level of mixed venous oxygen levels in pulmonary hypertension. European Heart Journal - Cardiovascular Imaging, Vol. 20(Supplement_2) View this article in WRRO
- P612Averaged, diastolic mitral inflow velocity mapping versus peak velocity for the assessment of left ventricular haemodynamics. European Heart Journal - Cardiovascular Imaging, Vol. 20(Supplement_2) View this article in WRRO
- A Multicentre Study of Anticoagulation in Operable Chronic Thromboembolic Pulmonary Hypertension. A56. SYMPATHY FOR THE CLOT: UPDATE ON PULMONARY EMBOLISM AND CTEPH
- The Incremental Shuttle Walking Test Can Be Used to Risk Stratify Patients with Pulmonary Hypertension as Per the European Respiratory/Cardiac Society Guidelines. A105. GLORY DAYS: THE LATEST CLINICAL RESEARCH IN PAH
- Cardiac MRI: Identifying Thresholds to Predict Mortality in Pulmonary Arterial Hypertension. B27. HEARTBREAKER: HEART FAILURE AND PULMONARY HYPERTENSION
- A novel cardiac magnetic resonance imaging model to predict level of mixed venous oxygen levels in pulmonary hypertension. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol. 20 (pp 121-121)
- Averaged, diastolic mitral inflow velocity mapping versus peak velocity for the assessment of left ventricular haemodynamics. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol. 20 (pp 494-495)
- P16 Identifying partial anomalous pulmonary venous drainage (PAPVD) in patients presenting with suspected pulmonary hypertension (PH). Under pressure: an update in pulmonary vascular disease
- S40 Phenotypic characterisation of GDF2 mutation carriers in a large cohort of patients with pulmonary arterial hypertension. Fundamental mechanisms of pulmonary arterial hypertension
- P18 Community-based pulmonary rehabilitation in patients with pulmonary hypertension: a feasibility study. Under pressure: an update in pulmonary vascular disease
- S43 Circulatory levels of microrna-34a expression identify patients with poor clinical outcome, and regulate pulmonary vascular cell phenotype. Fundamental mechanisms of pulmonary arterial hypertension
- Assessing the financial impact of pulmonary hypertension: a survey by the UK Pulmonary Hypertension Association (PHA-UK). Pulmonary hypertension
- Real world data from hospital episode statistics can be used to determine patients at risk of idiopathic pulmonary arterial hypertension. Pulmonary hypertension
- Anomalous pulmonary venous drainage (APVD) in patients with suspected pulmonary hypertension (PH). Pulmonary hypertension
- Good outcomes following elective lower limb orthopaedic surgery in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Pulmonary hypertension
- Incremental shuttle walking test distance is reduced in patients with pulmonary hypertension in WHO Functional Class I. Pulmonary hypertension
- Incremental Shuttle Walk Test predicts survival in non-Group 1 Pulmonary Hypertension without a ceiling effect. Pulmonary hypertension
- Prognostic Value of T1 Mapping in Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Transform-UK: A Phase 2 Trial of Tocilizumab in Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Diastolic Septal Angle Is an Independent Predictor of Right Ventricular Insertion Point T1 in Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Diagnostic Accuracy and Reproducibility of Unenhanced Computed Tomography in Suspected Pulmonary Hypertension: Pulmonary Arterial and Cardiac Metrics. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- European Respiratory Society Task Force: Exercise Training and Rehabilitation in Patients with Severe Chronic Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Cardiac MRI Measured Left Atrial Function Can Identify Patient with Pulmonary Hypertension Due to Left Heart Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Development of a Predictive Algorithm Based on Healthcare Behaviour to Support Earlier Diagnosis of Idiopathic Pulmonary Arterial Hypertension: Results of a Feasibility Study in the UK. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Sinus Rhythm Restoration is Safe and Leads to Clinical Improvement in Patients With Severe Pulmonary Hypertension.. CIRCULATION, Vol. 138
- Septal angle on MRI predicts combined pre and post capillary pulmonary hypertension. Thorax, Vol. 72(Suppl 3) (pp A31-A32), 6 December 2017 - 8 December 2017. View this article in WRRO
- P180 Managing pregnancy in pulmonary hypertension using a multi-professional approach: a 16-year experience in a specialist referral centre. Pulmonary vascular disease: monitoring and managing
- S108 Genome-wide association study in chronic thromboembolic pulmonary hypertension reveals new insights into aetiology. Advances in understanding chronic thrombo-embolic disease and pulmonary hypertension
- P183 Impact of patient choice on survival in patients with chronic thromboembolic pulmonary hypertension offered pulmonary endarterectomy. Pulmonary vascular disease: monitoring and managing
- S52 Computed tomography in the diagnosis of left heart disease in patients with suspected pulmonary hypertension. Diagnosing and treating pulmonary vascular disease
- P177 Computed tomography diagnostic model for diagnosis of pulmonary hypertension. Pulmonary vascular disease: monitoring and managing
- S111 Altered neutrophil phenotypes in pulmonary arterial hypertension. Advances in understanding chronic thrombo-embolic disease and pulmonary hypertension
- Development of a Novel Human Anti-OPG Antibody That Attenuates Experimental Pulmonary Arterial Hypertension. CIRCULATION, Vol. 136
- Managing pregnancy in pulmonary hypertension using a multi-professional approach: a 16-year experience in a specialist referral centre. Pulmonary Circulation and Pulmonary Vascular Disease
- Safe delivery of parturients with pulmonary hypertension: 16 years' experience in a national specialist referral centre. ANAESTHESIA, Vol. 72 (pp 56-56)
- Three Element Windkessel Model to Non-Invasively Assess PAH Patients: One Year Follow-up (pp 151-154)
- Loss of Function ABCC8 Mutations Are Associated With Pulmonary Arterial Hypertension. CIRCULATION, Vol. 136
- S107 Genotype-phenotype associations in pulmonary arterial hypertension caused by BMPR2 and EIF2AK4 variants. Thorax, Vol. 71(Suppl 3) (pp A63-A64)
- Non-invasive methods for the estimation of MPAP in COPD patients using cardiac MRI. Thorax, Vol. 71(Suppl 3) (pp A106-A107), 7 December 2016 - 9 December 2016. View this article in WRRO
- P245 Whole blood levels of microrna-34a predict survival and regulate genes associated with pulmonary arterial hypertension. Thorax, Vol. 71(Suppl 3) (pp A220.2-A221)
- P28 Chronic thromboembolic pulmonary hypertension: long term outcomes in surgical and non-surgical patients. Thorax, Vol. 71(Suppl 3) (pp A98.1-A98)
- S111 Differences in characteristics and outcomes in systemic sclerosis-associated and idiopathic pulmonary arterial hypertension. Thorax, Vol. 71(Suppl 3) (pp A66-A67)
- Response to treatment assessment in patients with PAH by MRI based computational modelling. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Idiopathic and systemic sclerosis-associated PAH: A comprehensive haemodynamic and radiological comparison. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Gas transfer measurement in systemic sclerosis associated pulmonary hypertension. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Change in right atrial minimal volume is a prognostic marker in pulmonary arterial hypertension (PAH). 1.3 Imaging
- Gas transfer measurement in systemic sclerosis associated pulmonary hypertension. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- Idiopathic and systemic sclerosis-associated PAH: A comprehensive haemodynamic and radiological comparison. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- MRI derived left atrial volume index predicts treatment response in patients with PAH. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Chronic thrombo-embolic pulmonary hypertension: Long-term outcomes in operated and non-operated patients. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Utility Of Deep Phenotyping In The Identification And Validation Of Novel Causal Whole Genome Sequencing Variation In Patients With Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 193
- Whole Genome Sequencing In Idiopathic And Heritable Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 193
- The Uk National Cohort Study Of Idiopathic And Heritable Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 193
- Extended Evaluation Of Emphasis-10 Quality Of Life Questionnaire In Ph. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 193
- Investigating The Diagnostic Potential Of Circulating Mirna Signatures In Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 193
- Plasma Proteome Analysis In Idiopathic Pulmonary Arterial Hypertension Identifies A Panel Of Prognostic Proteins. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 193
- Genome Wide Association Studies In Chronic Thromboembolic Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 193
- Deficiency Of Toll-Like Receptor 3 (tlr3) Exacerbates Pulmonary Hypertension In Mice. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 193
- Response to treatment assessment in patients with PAH by MRI based computational modelling. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- Assessment of lung microstructure in ILD with3He and129Xe MRI. 4.1 Clinical respiratory physiology, exercise and functional imaging
- Macitentan for pulmonary arterial hypertension (PAH): Early clinical experience of 94 patients. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Estimation of mPAP with MRI in pulmonary hypertension subgroups: Comparison with echocardiography. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Improved diagnostic accuracy of MRI in patients with suspected pulmonary hypertension with combined right ventricle and pulmonary artery metrics. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Diagnosis of pulmonary hypertension from MR image based computational models of pulmonary vascular haemodynamics and decision tree analysis. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Myocardial T1 mapping MRI in patients with PH and age-matched healthy volunteers. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- SAT0477 Rituximab Treatment for Connective Tissue Disease Associated Interstitial Lung Disease: A Retrospective Case Series. Annals of the Rheumatic Diseases, Vol. 74(Suppl 2) (pp 833.1-833)
- P170 Heart Rate Recovery At One Minute Following Incremental Shuttle Walk Test Predicts Outcome In Pulmonary Hypertension. Thorax, Vol. 69(Suppl 2) (pp A148-A149)
- P273 Assessment Of Lung Microstructure In Interstitial Lung Disease With Hyperpolarised Gas Mri. Thorax, Vol. 69(Suppl 2) (pp A192-A193)
- S121 The Utility Of The Incremental Shuttle Walking Test In Pulmonary Hypertension: Results From The Aspire Registry. Thorax, Vol. 69(Suppl 2) (pp A65-A65)
- S120 Right Ventricular Dysfunction In Pulmonary Hypertension With Combined Pulmonary Fibrosis And Emphysema Syndrome. Thorax, Vol. 69(Suppl 2) (pp A64-A65)
- P168 Reduced Gas Transfer (tlco) Predicts Poor Outcome In Patients With Pulmonary Hypertension And Heart Failure With Preserved Ejection Fraction. Thorax, Vol. 69(Suppl 2) (pp A148-A148)
- S118 Incidence And Severity Of Chronic Thromboembolic Pulmonary Hypertension Following The Introduction Of A One-stop Clinic For Acute Pulmonary Embolism. Thorax, Vol. 69(Suppl 2) (pp A63-A64)
- Age-dependent changes in whole-lung septal thickness measured by Xe-129 MRI: A comparison of healthy volunteers and subjects with IPF. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- Portopulmonary hypertension in United Kingdom; A contemporary, national, observational study. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- Age-dependent changes in whole-lung septal thickness measured by Xe-129 MRI: A comparison of healthy volunteers and subjects with IPF. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- Dissolved 129xe Mri - Delayed Gas Uptake Indicates Septal Thickening In Patients With Idiopathic Pulmonary Fibrosis And Systemic Sclerosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
- Automatic, Simultaneous, Non-invasive Measurements of Flow and Area in the Human Pulmonary Arteries from MRI Images (pp 259-264)
- Radio-Frequency Denervation Of The Pulmonary Artery Reduces Pulmonary Hypertension In An Acute Porcine Model. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
- HEPATOCYTE GROWTH FACTOR CONCENTRATION CORRELATES WITH HAEMODYNAMIC SEVERITY IN CONNECTIVE TISSUE DISEASE-ASSOCIATED PULMONARY ARTERIAL HYPERTENSION. THORAX, Vol. 68 (pp A146-A147)
- Analysis of flow vortices in the pulmonary artery of healthy volunteers and patients with pulmonary hypertension. EUROPEAN RESPIRATORY JOURNAL, Vol. 42
- Tumour necrosis factor-related apoptosis-inducing ligand is a novel therapeutic target in pulmonary arterial hypertension. The Lancet, Vol. 381, Supplement 1 (pp S47 --S47 -)
- MRI assessment of right atrial volume and function in pulmonary hypertension. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Prognostic value of ventricular volumes and function in patients with pulmonary hypertension due to chronic obstructive pulmonary disease. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- 'Idiopathic' pulmonary arterial hypertension with preserved lung function but co-existing parenchymal abnormalities: Response to treatment and survival. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Evaluation Of MR Lung Perfusion In The Assessment Of Chronic Thromboembolic Pulmonary Hypertension. C28. DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION
- Ambrisentan For Pulmonary Arterial Hypertension: Clinical Experience Of 101 Patients. C63. MANAGEMENT OF PULMONARY HYPERTENSION
- Prognostic Significance Of Change In Functional Class In Incident Idiopathic Pulmonary Arterial Hypertension. Results From The Pulmonary Hypertension Registry Of The United Kingdom And Ireland. B107. BIOMARKERS AND PREDICTORS OF OUTCOMES IN PULMONARY HYPERTENSION
- Imaging V/Q In Chronic Thromboembolic Pulmonary Hypertension With 3He And 1H MRI. B98. NOVEL APPROACHES TO LUNG IMAGING
- Characterising Peripheral Blood Lymphocyte Subpopulations In Clinical And Experimental Pulmonary Hypertension. C28. DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION
- Characteristics And Outcomes In Pulmonary Hypertension Associated With COPD/ Emphysema: Results From The ASPIRE Registry. B107. BIOMARKERS AND PREDICTORS OF OUTCOMES IN PULMONARY HYPERTENSION
- Elucidating The Mechanism By Which Monocytes Can Inhibit Hypoxic PA-SMC Proliferation. D33. ASTHMA PATHOGENESIS
- MR LV Systolic Eccentricity Index (SEI) Compared To Established Cardiac Mr Parameters For The Diagnosis Of PH: Correlation With Right Heart Catheterization. D26. PULMONARY VASCULAR AND RIGHT HEART PHYSIOLOGY
- INFLUENCE OF AGE ON CLINICAL PHENOTYPES OF INCIDENT IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION. RESULTS FROM THE PULMONARY HYPERTENSION REGISTRY OF THE UK AND IRELAND. THORAX, Vol. 66 (pp A34-A35)
- SERUM OSTEOPROTEGERIN PREDICTS MORTALITY IN A PROSPECTIVE STUDY ON INCIDENT CASES OF PULMONARY ARTERIAL HYPERTENSION. THORAX, Vol. 66 (pp A34-A34)
- PREDICTION OF SURVIVAL IN PULMONARY ARTERIAL HYPERTENSION USING SURVIVAL EQUATIONS. RESULTS FROM THE PULMONARY HYPERTENSION REGISTRY OF THE UK AND IRELAND. THORAX, Vol. 66 (pp A35-A36)
- DIAGNOSTIC UTILITY AND PROGNOSTIC VALUE OF QUANTITATIVE CARDIAC MR INDICES IN PATIENTS WITH SUSPECTED PULMONARY HYPERTENSION. THORAX, Vol. 66 (pp A34-A34)
- ACCURACY OF CONTRAST ENHANCED MR LUNG PERFUSION COMPARED TO PERFUSION SCINTIGRAPHY IN DIAGNOSING CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION. THORAX, Vol. 66 (pp A13-A14)
- PULMONARY HYPERTENSION (PH) ASSOCIATED WITH LUNG DISEASE/HYPOXIA. THORAX, Vol. 65 (pp A93-A93)
- CHARACTERISING T CELL SUB-POPULATIONS IN PULMONARY HYPERTENSION. THORAX, Vol. 65 (pp A91-A91)
- Patients with pulmonary hypertension have higher thrombin generation compared to atrial fibrillation individuals with the same INR. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Vol. 7 (pp 1161-1161)
- INCREMENTAL SHUTTLE AND 6-MINUTE WALK TESTS: CORRELATIONS WITH PULMONARY HAEMODYNAMICS AND CARDIOPULMONARY EXERCISE TESTING IN PULMONARY HYPERTENSION. THORAX, Vol. 63 (pp A55-A55)
- Reduced incremental shuttle walking test distance is associated with a worse survival in pulmonary arterial hypertension associated with systemic sclerosis. THORAX, Vol. 62 (pp A85-A85)
- Ventricular mass index measured using magnetic resonance imaging correlates with pulmonary artery pressure in patients with systemic sclerosis and suspected pulmonary arterial hypertension. THORAX, Vol. 62 (pp A84-A84)
- A randomised controlled trial to investigate the effects of a physiotherapist-led rehabilitation programme on exercise capacity and quality of life measures in patients with pulmonary hypertension. THORAX, Vol. 62 (pp A16-A17)
- Long-term safety profile of bosentan in paediatric patients with pulmonary arterial hypertension related to congenital heart defects or other aetiologies. EUROPEAN HEART JOURNAL, Vol. 27 (pp 401-401)
- Long-term safety profile of bosentan in patients with pulmonary arterial hypertension related to mixed connective tissue disease or systemic lupus erythematosus: Results from the Tracleer post marketing surveillance database. ANNALS OF THE RHEUMATIC DISEASES, Vol. 65 (pp 389-389)
- Abnormal post-exercise systolic blood pressure response to exercise is common in patients with suspected pulmonary hypertension. THORAX, Vol. 60 (pp II88-II88)
- Long term experience with bosentan for the treatment of idiopathic pulmonary arterial hypertension under routine conditions. THORAX, Vol. 60 (pp II88-II89)
- Treatment of pulmonary arterial hypertension in association with systemic to pulmonary shunts: A retrospective review. THORAX, Vol. 60 (pp II89-II89)
- Haemolytic disorders complicated by pulmonary hypertension. THORAX, Vol. 60 (pp II87-II88)
- Clinical experience with bosentan for the treatment of pulmonary hypertension associated with congenital heart disease. EUROPEAN HEART JOURNAL, Vol. 26 (pp 215-216)
- Long-term safety profile of bosentan in patients with chronic thromboembolic pulmonary hypertension (CTEPH): results from the TRAX database. EUROPEAN HEART JOURNAL, Vol. 26 (pp 113-113)
- Long-term safety profile of bosentan in patients with systemic sclerosis and pulmonary arterial hypertension: Results from the TRAX database. ANNALS OF THE RHEUMATIC DISEASES, Vol. 64 (pp 294-294)
- Pulmonary hypertension as a complication of haemolysis. BRITISH JOURNAL OF HAEMATOLOGY, Vol. 129 (pp 47-47)
- Incremental shuttle walking test distance predicts prognosis in patients with pulmonary hypertension treated with targeted pulmonary vascular therapy. THORAX, Vol. 59(1) (pp 85-85)
- Use of nebulised iloprost therapy in early pregnancy in patients with pulmonary hypertension. THORAX, Vol. 59(1) (pp 86-86)
- Increased pulmonary artery to aortic ratio measured using magnetic resonance imaging identifies patients with pulmonary hypertension. THORAX, Vol. 59(1) (pp 8-8)
- Elevated factor VIII : C levels in patients with pulmonary hypertension. A marker of endothelial dysfunction?. BRITISH JOURNAL OF HAEMATOLOGY, Vol. 125 (pp 46-46)
- Identification of patients with systemic sclerosis and pulmonary hypertension on exercise using a simple screening protocol. THORAX, Vol. 58 (pp 83-83)
- Elevated factor FVIII: C levels as a marker of endothelial dysfunction in patients with pulmonary hypertension. THORAX, Vol. 58 (pp 9-9)
- Elevated pulmonary: Aortic ratio in patients with pulmonary arterial hypertension associated with systemic sclerosis. THORAX, Vol. 57
- The haemodynamic effects of "pulsed" inhaled nitric oxide in patients with pulmonary hypertension. THORAX, Vol. 57
- Compassionate treatment of pulmonary hypertension with long term inhaled nitric oxide and oral sildenafil (Viagra((R))). THORAX, Vol. 57
- The renin response to frusemide in man is nitric oxide-dependent. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol. 42(5) (pp P652-P652)
Other
- MRI Prediction of Precapillary Pulmonary Hypertension according to the Sixth World Symposium on Pulmonary Hypertension. Radiology, 294(2), 482-482. View this article in WRRO
- Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data. Scientific Reports, 8(1).
- Reply to Hou et al.: Can Magnetic Resonance Imaging Effectively Evaluate the Prognosis of Patients with Pulmonary Arterial Hypertension?. American Journal of Respiratory and Critical Care Medicine, 197(5), 676-677.
- Response to: ‘CT assessment for pulmonary hypertension requires systematic assessment of cardiac, vascular and parenchymal signs’ by Marloeset al. Thorax, 70(11), 1087.2-1088.
- 3D contrast-enhanced lung perfusion MRI is an effective screening tool for chronic thromboembolic pulmonary hypertension: results from the ASPIRE Registry.. Thorax, 68(7), 677-678.
Preprints
- Pulmonary Hypertension: Intensification and Personalisation of Combination Rx (PHoenix): A phase IV randomised trial for the evaluation of dose-response and clinical efficacy of riociguat and selexipag using implanted technologies, Cold Spring Harbor Laboratory.
- Remote evaluation of risk and physiological response to therapeutic escalation and clinical worsening in patients with pulmonary hypertension, Cold Spring Harbor Laboratory.
- First genotype-phenotype study in TBX4 syndrome: gain-of-function mutations causative for lung disease, Cold Spring Harbor Laboratory.
- Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension, Cold Spring Harbor Laboratory.
- Genetic determinants of risk and survival in pulmonary arterial hypertension, Cold Spring Harbor Laboratory.
- Identification of novel rare sequence variation underlying heritable pulmonary arterial hypertension, Cold Spring Harbor Laboratory.
- Autoimmunity is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension.
- Teaching interests
-
I am involved in undergraduate and post-graduate teaching of students and deliver invited lectures at national and international meetings.
- Professional activities and memberships
-
- Fellow American College of Chest Physicians (2000), Fellow Royal College of Physicians (2009), Fellow European Society of Cardiology (2010), Fellow of Pulmonary Vascular Research Institute (2011)
- Director of National Pulmonary Hypertension Centre Sheffield (2001 onwards)
- Board member of International Workshop on Pulmonary Functional Imaging (2009 onwards)
- Board member of the National Pulmonary Hypertension Audit Reference Group (2013 onwards)
- Member of the Insigneo Institute for in silico medicine (2013 onwards)
- Board member of the Clinical Reference Group for Specialist Respiratory Medicine (2016 onwards)
- Lead of the PVRI Imaging Task force and a member of PVRI Task Force on Women’s Health (2016 onwards)
- Board member of Clinical Reference Group (CRG) for Pulmonary Hypertension (2012-2016)
- Chair of the UK and Ireland Pulmonary Hypertension Physicians Committee (April 2013-2016)
- Chair of the Pulmonary Vascular Specialist Advisory Group to the British Thoracic Society (2009-2012)