Professor Andy Swift
MBChB MRCP FRCR PhD
Clinical Medicine, School of Medicine and Population Health
Professor of Cardiothoracic Radiology
+44 114 215 9143
Full contact details
Clinical Medicine, School of Medicine and Population Health
University MRI Unit, C Floor
Royal Hallamshire Hospital
Glossop Road
Sheffield
S10 2JF
- Profile
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For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk
I studied medicine at Sheffield University, graduating in 2003. Following basic medical training I undertook specialist radiology training on the Hull Radiology training scheme.
I joined the University of Sheffield in 2010 as a NIHR Cardiovascular Clinical Fellow and I was awarded a NIHR Biomedical Research Fellowship to complete my PhD entitled “Developing the Role of Magnetic Resonance Imaging in Pulmonary Hypertension”. I am interested in the use of computer science in medicine to improve diagnosis and prognostication, I was employed by INSIGNEO for 5 years as a research fellow and am now a Wellcome Trust Clinical Career Development Fellow.
- Research interests
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My research interests include the clinical application of novel imaging techniques and analysis approaches in patients with cardiac and pulmonary disease.
Current projects
- Machine learning to improve disease assessment in cardiac and pulmonary disease.
- Developing MRI as diagnostic and prognostic tool - DITCH.
- Lung subtraction Iodine mapping in patients with suspected chronic emboli - INSITGATE.
- Repeatability of magnetic resonance imaging cardiopulmonary metrics in pulmonary arterial hypertension - Implications for trial design.
- Understanding the phenotype of genetic variants using magnetic resonance imaging and computed tomography - COHORT study.
- Risk stratification of patients with cardiac and pulmonary disorders.
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Identifying At-Risk Patients with Combined Pre- and Postcapillary Pulmonary Hypertension Using Interventricular Septal Angle at Cardiac MRI. Radiology, 289(1), 180120-180120. View this article in WRRO
- The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension. European Respiratory Journal, 52(3). View this article in WRRO
- Pulmonary Artery Size in Interstitial Lung Disease and Pulmonary Hypertension: Association with Interstitial Lung Disease Severity and Diagnostic Utility. Frontiers in Cardiovascular Medicine, 5. View this article in WRRO
- CT derived left atrial size identifies left heart disease in suspected pulmonary hypertension: Derivation and validation of predictive thresholds. International Journal of Cardiology, 260, 172-177. View this article in WRRO
- Phenotypic Characterisation of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically with Pulmonary Arterial Hypertension.. Circulation, 136(21), 2022-2033. View this article in WRRO
- Magnetic Resonance Imaging in the Prognostic Evaluation of Patients with Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 196(2). View this article in WRRO
- Longitudinal and Transverse Right Ventricular Function in Pulmonary Hypertension: Cardiovascular Magnetic Resonance Imaging Study from the ASPIRE Registry. Pulmonary Circulation, 5(3), 557-564.
- Right Ventricular Sex Differences in Patients with Idiopathic Pulmonary Arterial Hypertension Characterised by Magnetic Resonance Imaging: Pair-Matched Case Controlled Study. PLOS ONE, 10(5), e0127415-e0127415. View this article in WRRO
- LGE Patterns in Pulmonary Hypertension Do Not Impact Overall Mortality. JACC: Cardiovascular Imaging, 7(12), 1209-1217.
- Dynamic contrast-enhanced magnetic resonance imaging in patients with pulmonary arterial hypertension.. Pulm Circ, 4(1), 61-70. View this article in WRRO
- Prognostic value of cardiovascular magnetic resonance imaging measurements corrected for age and sex in idiopathic pulmonary arterial hypertension.. Circ Cardiovasc Imaging, 7(1), 100-106.
- Noninvasive estimation of pa pressure, flow, and resistance with CMR imaging: Derivation and prospective validation study from the aspire registry. JACC: Cardiovascular Imaging, 6(10), 1036-1047.
All publications
Journal articles
- Corrigendum to “Acute myocardial calcification demonstrated on multimodal imaging” [Journal of Cardiovascular Magnetic Resonance 26S1 (2024) 100939]. Journal of Cardiovascular Magnetic Resonance, 26(2), 101058-101058.
- Functional status is associated with mean right atrial pressure derived from cardiac MRI. European Heart Journal, 45(Supplement_1).
- Automated quantification of simple and complex aortic flow using 2D phase contrast MRI. Medicina, 60(10). View this article in WRRO
- Meta-Analysis of Interobserver Agreement in Assessment of Interstitial Lung Disease Using High-Resolution CT. Radiology, 313(1).
- The spectrum of systemic sclerosis-associated pulmonary hypertension: Insights from the ASPIRE registry. The Journal of Heart and Lung Transplantation, 43(10), 1629-1639. View this article in WRRO
- Risk factors for raised left ventricular filling pressure by cardiovascular magnetic resonance: prognostic insights. ESC Heart Failure. View this article in WRRO
- FACILITATING THE USE OF ROUTINE DATA TO EVALUATE ARTIFICIAL INTELLIGENCE SOLUTIONS: LESSONS FROM THE <BLINDED> CURATION WORKSHOP. Clinical Radiology.
- Development and validation of AI-derived segmentation of four-chamber cine cardiac magnetic resonance. European Radiology Experimental, 8(1). View this article in WRRO
- Applications of artificial intelligence in computed tomography imaging for phenotyping pulmonary hypertension. Current Opinion in Pulmonary Medicine.
- Association of risk assessment at diagnosis with healthcare resource utilization and health‐related quality of life outcomes in pulmonary arterial hypertension. Pulmonary Circulation, 14(3). View this article in WRRO
- Sex-specific cardiac magnetic resonance pulmonary capillary wedge pressure. European Heart Journal Open, 4(3). View this article in WRRO
- Age, sex, and lung volume dependence of dissolved xenon‐129 MRI gas exchange metrics. Magnetic Resonance in Medicine. View this article in WRRO
- Characterisation of the octogenarians presenting to the diagnostic heart failure clinic: SHEAF registry. Open Heart, 11. View this article in WRRO
- A systematic review of artificial intelligence tools for chronic pulmonary embolism on CT pulmonary angiography. Frontiers in Radiology, 4, 1335349.
- Diagnostic Accuracy of Automatic Tricuspid Regurgitation Jet Velocity for Detecting Pulmonary Hypertension. The Journal of Heart and Lung Transplantation, 43(4), S114-S115.
- Validation of 2D flow MRI for helical and vortical flows. Open Heart, 11(1), e002451-e002451.
- Clinical assessment of an AI tool for measuring biventricular parameters on cardiac MR. Frontiers in Cardiovascular Medicine, 11, 1279298.
- Improving Prognostication in Pulmonary Hypertension Using AI-quantified Fibrosis and Radiologic Severity Scoring at Baseline CT. Radiology, 310(2).
- Effect of Macitentan in Pulmonary Arterial Hypertension and the Relationship Between Echocardiography and cMRI Variables: REPAIR Echocardiography Sub-study Results. Cardiology and Therapy.
- Comparison of cardiac magnetic resonance imaging, functional and haemodynamic variables in pulmonary arterial hypertension: insights from REPAIR. ERJ Open Research, 10(1). View this article in WRRO
- Risk assessment and real-world outcomes in chronic thromboembolic pulmonary hypertension: insights from a UK pulmonary hypertension referral service. BMJ Open, 14(1). View this article in WRRO
- Advancing Risk Stratification in Pulmonary Arterial Hypertension Through Cardiac MRI. CHEST, 165(1), 12-13.
- Pre- and Post-treatment CMR Measurement Changes in Pulmonary Arterial Hypertension. Journal of Cardiovascular Magnetic Resonance, 26, 100242-100242.
- Acute Myocardial Calcification Demonstrated on Multimodal Imaging. Journal of Cardiovascular Magnetic Resonance, 26, 100939-100939.
- Cardiac MR modelling of systolic and diastolic blood pressure. Open Heart, 2023(10). View this article in WRRO
- Anatomical characterization of pulmonary artery and implications to pulmonary artery pressure monitor implantation. Scientific Reports, 13(1). View this article in WRRO
- Evaluating the performance of artificial intelligence software for lung nodule detection on chest radiographs in a retrospective real-world UK population. BMJ Open, 13(11), e077348-e077348.
- Abstract 13918: Improvement of Pulmonary Arterial Hypertension (PAH) Risk Assessment Model Using Cardiac Magnetic Resonance Imaging Variables. Circulation, 148(Suppl_1).
- Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. Nature Cardiovascular Research, 2, 917-936. View this article in WRRO
- Multicenter standardization of phase-resolved functional lung MRI in patients with suspected chronic thromboembolic pulmonary hypertension. Journal of Magnetic Resonance Imaging. View this article in WRRO
- Cardiac magnetic resonance left ventricular filling pressure is linked to symptoms, signs and prognosis in heart failure. ESC Heart Failure.
- Establishing minimally important differences for cardiac MRI end-points in pulmonary arterial hypertension. European Respiratory Journal, 62(2), 2202225-2202225.
- Risk factors for raised left ventricular filling pressure by cardiovascular magnetic resonance: prognostic insights from UK Biobank. European Heart Journal - Cardiovascular Imaging, 24(Supplement_1).
- Assessment of right ventricular function—a state of the art. Current Heart Failure Reports, 20(3), 194-207.
- Artificial Intelligence framework with traditional computer vision and deep learning approaches for optimal automatic segmentation of left ventricle with scar. Artificial Intelligence in Medicine, 102610-102610.
- An acute increase in left atrial volume and left ventricular filling pressure during adenosine administered myocardial hyperaemia: CMR first-pass perfusion study. BMC Cardiovascular Disorders, 23.
- Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. Chest.
- Pulmonary Artery Strain Predicts Prognosis in Pulmonary Arterial Hypertension. JACC: Cardiovascular Imaging.
- A transparent artificial intelligence framework to assess lung disease in pulmonary hypertension. Scientific Reports, 13.
- Quantifying myocardial blood flow and resistance using 4D-flow cardiac magnetic resonance imaging. Cardiology Research and Practice, 2023.
- How should studies using AI be reported? Lessons from a systematic review in cardiac MRI. Frontiers in Radiology, 3.
- Automated 4D flow cardiac MRI pipeline to derive peak mitral inflow diastolic velocities using short-axis cine stack: two centre validation study against echocardiographic pulse-wave doppler. BMC Cardiovascular Disorders, 23(1).
- Semi-automatic thresholding of RV trabeculation improves repeatability and diagnostic value in suspected pulmonary hypertension. Frontiers in Cardiovascular Medicine, 9.
- Automatic development of 3D anatomical models of border zone and core scar regions in the left ventricle. Computerized Medical Imaging and Graphics, 103, 102152-102152.
- 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Respiratory Journal, 61(1), 2200879-2200879.
- Uncertainty Estimation for Heatmap-based Landmark Localization. IEEE Transactions on Medical Imaging, 1-1.
- Abstract 14089: CT Analysis of Small Pulmonary Vessels and Its Association With Pulmonary Function Tests and Prognosis in Pulmonary Hypertension. Circulation, 146(Suppl_1), a14089-a14089.
- Quality of reporting of artificial intelligence studies: Lessons learnt from a systematic review of the literature. Clinical Radiology, 77, e21-e21.
- Now you see: Cardiac findings on general CT. Clinical Radiology, 77, e22-e22.
- A robust COVID-19 mortality prediction calculator based on lymphocyte count, urea, C-reactive protein, age and sex (LUCAS) with chest X-rays. Scientific Reports, 12(1).
- Fully automatic cardiac four chamber and great vessel segmentation on CT pulmonary angiography using deep learning. Frontiers in Cardiovascular Medicine, 9.
- Kat-ARC accelerated 4D flow CMR: clinical validation for transvalvular flow and peak velocity assessment. European Radiology Experimental, 6.
- Validation of Artificial Intelligence Cardiac MRI Measurements: Relationship to Heart Catheterization and Mortality Prediction. Radiology, 304(3), E56-E56.
- 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Heart Journal, 43(38), 3618-3731.
- Image phenotyping of preterm-born children using hyperpolarised 129Xe lung MRI and multiple-breath washout. American Journal of Respiratory and Critical Care Medicine. View this article in WRRO
- The role of artificial intelligence in predicting outcomes by cardiovascular magnetic resonance : a comprehensive systematic review. Medicina, 58(8). View this article in WRRO
- Importance of cardiac magnetic resonance imaging assessment of left ventricular filling pressure at resting state. European Heart Journal, 43(36), 3495-3495.
- Phenotyping of idiopathic pulmonary arterial hypertension: a registry analysis. The Lancet Respiratory Medicine.
- Validation of time-resolved, automated peak trans-mitral velocity tracking: Two center four-dimensional flow cardiovascular magnetic resonance study. International Journal of Cardiology. View this article in WRRO
- Validation of Artificial Intelligence Cardiac MRI Measurements: Relationship to Heart Catheterization and Mortality Prediction.. Radiology, 212929.
- Cardiovascular medication in patients with raised NT-proBNP, but no heart failure in the SHEAF registry. Open Heart, 9(1). View this article in WRRO
- Mitral regurgitation quantified by CMR 4D-flow is associated with microvascular obstruction post reperfused ST-segment elevation myocardial infarction. BMC Research Notes, 15(1).
- Right ventricular remodelling in pulmonary arterial hypertension predicts treatment response.. Heart. View this article in WRRO
- Cardiac magnetic resonance identifies raised left ventricular filling pressure: prognostic implications. European Heart Journal. View this article in WRRO
- Machine learning cardiac-MRI features predict mortality in newly diagnosed pulmonary arterial hypertension. European Heart Journal - Digital Health. View this article in WRRO
- Validation of aortic valve pressure gradient quantification using semi-automated 4D flow CMR pipeline. BMC Research Notes, 15(1).
- Training and clinical testing of artificial intelligence derived right atrial cardiovascular magnetic resonance measurements. Journal of Cardiovascular Magnetic Resonance, 24(1).
- Imaging and risk stratification in pulmonary arterial hypertension : time to include right ventricular assessment. Frontiers in Cardiovascular Medicine, 9. View this article in WRRO
- Valvular cardiomyopathy : the value of cardiovascular magnetic resonance imaging. Cardiology Research and Practice, 2022. View this article in WRRO
- Computed tomography lung parenchymal descriptions in routine radiological reporting have diagnostic and prognostic utility in patients with idiopathic pulmonary arterial hypertension and pulmonary hypertension associated with lung disease. ERJ Open Research, 8(1). View this article in WRRO
- The REPAIR Study : effects of macitentan on RV structure and function in pulmonary arterial hypertension. JACC: Cardiovascular Imaging, 15(2), 240-253. View this article in WRRO
- Mitral regurgitation quantification by cardiac magnetic resonance imaging (MRI) remains reproducible between software solutions. Wellcome Open Research, 6, 253-253.
- Myocardial inflammation and energetics by cardiac MRI : a review of emerging techniques. BMC Medical Imaging, 21(1). View this article in WRRO
- DenResCov-19: a deep transfer learning network for robust automatic classification of COVID-19, pneumonia, and tuberculosis from X-rays. Computerized Medical Imaging and Graphics, 94. View this article in WRRO
- Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood. Nature Communications, 12. View this article in WRRO
- Towards nationally curated data archives for clinical radiology image analysis at scale: Learnings from national data collection in response to a pandemic. DIGITAL HEALTH, 7, 205520762110486-205520762110486.
- Four-dimensional flow cardiovascular magnetic resonance for the assessment of mitral stenosis. European Heart Journal: Case Reports, 5(12). View this article in WRRO
- Mitral regurgitation quantification by cardiac magnetic resonance imaging (MRI) remains reproducible between software solutions. Wellcome Open Research, 6, 253.
- Unenhanced computed tomography as a diagnostic tool in suspected pulmonary hypertension: a retrospective cross-sectional pilot study. Wellcome Open Research, 6, 249.
- Xenon ventilation MRI in difficult asthma; initial experience in a clinical setting. European Respiratory Journal, 7(3). View this article in WRRO
- Diagnostic accuracy of handheld cardiac ultrasound device for assessment of left ventricular structure and function: systematic review and meta-analysis. Heart. View this article in WRRO
- Cardiovascular examination using hand-held cardiac ultrasound. Journal of Echocardiography. View this article in WRRO
- Reproducibility of left ventricular blood flow kinetic energy measured by four-dimensional flow CMR. BMC Research Notes, 14(1).
- Fully automated CMR derived stroke volume correlates with right heart catheter measurements in patients with suspected pulmonary hypertension. European Heart Journal - Cardiovascular Imaging, 22(Supplement_2).
- High interstudy repeatability of automatic deep learnt biventricular CMR measurements. European Heart Journal - Cardiovascular Imaging, 22(Supplement_2).
- Clinical translation of three-dimensional scar, diffusion tensor imaging, four-dimensional flow, and quantitative perfusion in cardiac MRI: a comprehensive review. Frontiers in Cardiovascular Medicine, 8. View this article in WRRO
- Myocardial T1-mapping and extracellular volume in pulmonary arterial hypertension : a systematic review and meta-analysis. Magnetic Resonance Imaging, 79, 66-75. View this article in WRRO
- Feasibility and validation of trans-valvular flow derived by four-dimensional flow cardiovascular magnetic resonance imaging in patients with atrial fibrillation. Wellcome Open Research, 6. View this article in WRRO
- Cardiovascular magnetic resonance predicts all-cause mortality in pulmonary hypertension associated with heart failure with preserved ejection fraction. International Journal of Cardiovascular Imaging. View this article in WRRO
- Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. Genome Medicine, 13(1), 80-80. View this article in WRRO
- COMPARISON OF STANDARDIZED TREATMENT EFFECT SIZES FOR INVASIVE AND NON-INVASIVE ENDPOINTS IN PULMONARY ARTERIAL HYPERTENSION: INSIGHTS FROM THE REPAIR STUDY. Journal of the American College of Cardiology, 77(18), 1672.
- Pulmonary Hypertension in Association with Lung Disease: Quantitative CT and Artificial Intelligence to the Rescue? State-of-the-Art Review. Diagnostics, 11(4), 679.
- Correction. JACC: Cardiovascular Imaging, 14(4), 884-884.
- Standard and emerging CMR methods for mitral regurgitation quantification. International Journal of Cardiology.
- Cardiac MRI for the prognostication of heart failure with preserved ejection fraction: A systematic review and meta-analysis. Magnetic Resonance Imaging, 76, 116-122. View this article in WRRO
- Left ventricular fibrosis and hypertrophy are associated with mortality in heart failure with preserved ejection fraction. Scientific Reports, 11(1). View this article in WRRO
- Characterisation of the patients with suspected heart failure: experience from the SHEAF registry. Open Heart, 8(1).
- Peripheral and proximal lung ventilation in asthma; short-term variation and response to bronchodilator. Journal of Allergy and Clinical Immunology. View this article in WRRO
- Cardiac Magnetic Resonance in Pulmonary Hypertension—an Update. Current Cardiovascular Imaging Reports, 13(12).
- Right Ventricular Adaptation Assessed Using Cardiac Magnetic Resonance Predicts Survival in Pulmonary Arterial Hypertension. JACC: Cardiovascular Imaging.
- Effect of macitentan on left ventricular (LV) function in pulmonary arterial hypertension (PAH): results from REPAIR. European Heart Journal, 41(Supplement_2).
- Cardiac-MRI predicts clinical worsening and mortality in pulmonary arterial hypertension: a systematic review and meta-analysis. JACC: Cardiovascular Imaging.
- Validation of four-dimensional flow cardiovascular magnetic resonance for aortic stenosis assessment. Scientific Reports, 10(1). View this article in WRRO
- Age-associated changes in 4D flow CMR derived tricuspid valvular flow and right ventricular blood flow kinetic energy. Scientific Reports, 10(1). View this article in WRRO
- Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension. European Respiratory Journal, 55(6). View this article in WRRO
- CT Pulmonary Angiography in Chronic Thromboembolic Disease: Where Do We Stand?. Radiology, 296(2), 430-431.
- Comparison of MRI and VQ-SPECT as a Screening Test for Patients With Suspected CTEPH: CHANGE-MRI Study Design and Rationale. Frontiers in Cardiovascular Medicine, 7. View this article in WRRO
- Partial anomalous pulmonary venous drainage in patients presenting with suspected pulmonary hypertension: A series of 90 patients from the ASPIRE registry. Respirology. View this article in WRRO
- The role of imaging in malignant pleural mesothelioma: an update after the 2018 BTS guidelines. Clinical Radiology, 75(6), 423-432.
- Identification of cardiac MRI thresholds for risk stratification in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine, 201(4), 458-468. View this article in WRRO
- A machine learning cardiac magnetic resonance approach to extract disease features and automate pulmonary arterial hypertension diagnosis. European Heart Journal - Cardiovascular Imaging. View this article in WRRO
- Assessment of mitral valve regurgitation by cardiovascular magnetic resonance imaging. Nature Reviews Cardiology. View this article in WRRO
- IodiNe Subtraction mapping in the diagnosis of Pulmonary chronIc thRomboEmbolic disease (INSPIRE) : rationale and methodology of a cross-sectional observational diagnostic study. Contemporary Clinical Trials Communications, 15. View this article in WRRO
- A systematic review of 4D-flow MRI derived mitral regurgitation quantification methods. Frontiers in Cardiovascular Medicine, 6. View this article in WRRO
- The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry. Pulmonary Circulation, 9(2). View this article in WRRO
- Experimental and quantitative imaging techniques in interstitial lung disease. Thorax, 74(6), 611-619. View this article in WRRO
- EXPRESS: Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI).. Pulmonary Circulation. View this article in WRRO
- A Systematic Review of Right Ventricular Diastolic Assessment by 4D Flow CMR. BioMed Research International, 2019. View this article in WRRO
- Diagnostic and prognostic significance of cardiovascular magnetic resonance native myocardial T1 mapping in patients with pulmonary hypertension. Journal of Cardiovascular Magnetic Resonance, 20. View this article in WRRO
- Diagnosis of Pulmonary Hypertension with Cardiac MRI: Derivation and Validation of Regression Models.. Radiology, 290(1). View this article in WRRO
- Drug-Induced Interstitial Lung Disease: A Systematic Review.. J Clin Med, 7(10). View this article in WRRO
- Identifying At-Risk Patients with Combined Pre- and Postcapillary Pulmonary Hypertension Using Interventricular Septal Angle at Cardiac MRI. Radiology, 289(1), 180120-180120. View this article in WRRO
- Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification. Journal of Cardiovascular Magnetic Resonance, 20(1).
- The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension. European Respiratory Journal, 52(3). View this article in WRRO
- Novel imaging techniques in pulmonary hypertension. Current Opinion in Cardiology, 33(6), 587-593.
- Magnetic resonance angiography for the primary diagnosis of pulmonary embolism: A review from the international workshop for pulmonary functional imaging. World Journal of Radiology, 10(6), 52-64. View this article in WRRO
- Pulmonary Artery Size in Interstitial Lung Disease and Pulmonary Hypertension: Association with Interstitial Lung Disease Severity and Diagnostic Utility. Frontiers in Cardiovascular Medicine, 5. View this article in WRRO
- CT derived left atrial size identifies left heart disease in suspected pulmonary hypertension: Derivation and validation of predictive thresholds. International Journal of Cardiology, 260, 172-177. View this article in WRRO
- Role of Cardiac T1 Mapping and Extracellular Volume (ECV) in the Assessment of Myocardial Infarction. The Anatolian Journal of Cardiology. View this article in WRRO
- Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5T. Journal of Magnetic Resonance Imaging, 48(3), 632-642. View this article in WRRO
- Current and emerging imaging techniques in the diagnosis and assessment of pulmonary hypertension. Expert Review of Respiratory Medicine, 12(2), 145-160. View this article in WRRO
- Phenotypic Characterisation of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically with Pulmonary Arterial Hypertension.. Circulation, 136(21), 2022-2033. View this article in WRRO
- Lung perfusion: MRI vs. SPECT for screening in suspected chronic thromboembolic pulmonary hypertension. Journal of Magnetic Resonance Imaging, 46(6), 1693-1697. View this article in WRRO
- Septal angle on MRI predicts combined pre- and post-capillary pulmonary hypertension. Clinical Radiology, 72, S1-S2.
- Commentary on: Survey of UK imaging practice for the investigation of pulmonary embolism in pregnancy. Clinical Radiology, 72(8), 702-703. View this article in WRRO
- Magnetic Resonance Imaging in the Prognostic Evaluation of Patients with Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 196(2). View this article in WRRO
- Incremental Shuttle Walking Test Distance and Autonomic Dysfunction Predict Survival in Pulmonary Arterial Hypertension. The Journal of Heart and Lung Transplantation. View this article in WRRO
- Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI. Thorax, 72(8), 760-762. View this article in WRRO
- Idiopathic and Systemic Sclerosis associated Pulmonary Arterial Hypertension: A Comparison of Demographic, Haemodynamic and Magnetic Resonance Imaging Characteristics and Outcomes.. Chest.
- Pulmonary MR angiography and perfusion imaging—A review of methods and applications. European Journal of Radiology, 86, 361-370. View this article in WRRO
- Diagnosis of Pulmonary Hypertension from Magnetic Resonance Imaging–Based Computational Models and Decision Tree Analysis. Pulmonary Circulation, 6(2), 181-190. View this article in WRRO
- Pulmonary ventilation and micro-structural findings in congenital diaphragmatic hernia. Pediatric Pulmonology, 51(5), 517-524.
- An Algorithm for the Segmentation of Highly Abnormal Hearts Using a Generic Statistical Shape Model. IEEE Transactions on Medical Imaging, 35(3), 845-859.
- Pulmonary Hypertension in Patients with Heart Failure and Preserved Ejection Fraction: Differential Diagnosis and Management. Pulmonary Circulation, 6(1), 3-14.
- Comparison of CT-based Lobar Ventilation with3He MR Imaging Ventilation Measurements. Radiology, 278(2), 585-592.
- Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension. Current Cardiovascular Imaging Reports, 8(12).
- Pulmonary Artery Denervation Reduces Pulmonary Artery Pressure and Induces Histological Changes in an Acute Porcine Model of Pulmonary Hypertension. Circulation: Cardiovascular Interventions, 8(11), e002569-e002569. View this article in WRRO
- Analysis of Published Criteria for Clinically Inactive Disease in a Large Juvenile Dermatomyositis Cohort Shows That Skin Disease Is Underestimated. Arthritis & Rheumatology, 67(9), 2495-2502.
- Longitudinal and Transverse Right Ventricular Function in Pulmonary Hypertension: Cardiovascular Magnetic Resonance Imaging Study from the ASPIRE Registry. Pulmonary Circulation, 5(3), 557-564.
- Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 192(2), 254-257. View this article in WRRO
- Right Ventricular Sex Differences in Patients with Idiopathic Pulmonary Arterial Hypertension Characterised by Magnetic Resonance Imaging: Pair-Matched Case Controlled Study. PLOS ONE, 10(5), e0127415-e0127415. View this article in WRRO
- CT features of pulmonary arterial hypertension and its major subtypes: a systematic CT evaluation of 292 patients from the ASPIRE Registry. Thorax, 70(4), 382-387. View this article in WRRO
- Native T1 myocardial tissue characterisation in patients with pulmonary hypertension: findings from International T1 Multicentre Study. Journal of Cardiovascular Magnetic Resonance, 17(S1).
- A method for quantitative analysis of regional lung ventilation using deformable image registration of CT and hybrid hyperpolarized gas/ 1 H MRI. Physics in Medicine and Biology, 59(23), 7267-7277. View this article in WRRO
- LGE Patterns in Pulmonary Hypertension Do Not Impact Overall Mortality. JACC: Cardiovascular Imaging, 7(12), 1209-1217.
- MRI model-based non-invasive differential diagnosis in pulmonary hypertension. Journal of Biomechanics, 47(12), 2941-2947. View this article in WRRO
- Magnetic Resonance Imaging of Ventilation and Perfusion Changes in Response to Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine, 190(5), e18-e19. View this article in WRRO
- Dynamic contrast-enhanced magnetic resonance imaging in patients with pulmonary arterial hypertension.. Pulm Circ, 4(1), 61-70. View this article in WRRO
- Quantitative magnetic resonance imaging of pulmonary hypertension: a practical approach to the current state of the art.. J Thorac Imaging, 29(2), 68-79.
- Prognostic value of cardiovascular magnetic resonance imaging measurements corrected for age and sex in idiopathic pulmonary arterial hypertension.. Circ Cardiovasc Imaging, 7(1), 100-106.
- Prognostic value of right ventricular function in patients with severe pulmonary hypertension associated with respiratory disease. EUROPEAN RESPIRATORY JOURNAL, 42.
- Primary pulmonary artery sarcoma and coexisting chronic thromboembolic pulmonary hypertension.. Am J Respir Crit Care Med, 188(5), e7-e8.
- Single centre prospective study of the efficacy of percutaneous cement augmentation in the treatment of vertebral compression fractures. British Journal of Neurosurgery, 27(4), 459-464.
- Noninvasive estimation of pa pressure, flow, and resistance with CMR imaging: Derivation and prospective validation study from the aspire registry. JACC: Cardiovascular Imaging, 6(10), 1036-1047.
- Pulmonary hypertension in COPD: results from the ASPIRE registry.. Eur Respir J, 41(6), 1292-1301.
- Longitudinal And Transverse Right Ventricular Function In Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187.
- CT Features Of Pulmonary Arterial Hypertension And Its Major Subtypes: A Study Of 292 Patients. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187.
- Use of a digitally reconstructed radiograph-based computer simulation for the optimisation of chest radiographic techniques for computed radiography imaging systems.. Br J Radiol, 85(1017), e630-e639.
- Diagnostic accuracy of cardiovascular magnetic resonance imaging of right ventricular morphology and function in the assessment of suspected pulmonary hypertension results from the ASPIRE registry.. J Cardiovasc Magn Reson, 14, 40. View this article in WRRO
- Comparison of the diagnostic utility of cardiac magnetic resonance imaging, computed tomography, and echocardiography in assessment of suspected pulmonary arterial hypertension in patients with connective tissue disease.. J Rheumatol, 39(6), 1265-1274.
- Lung morphology assessment with balanced steady-state free precession MR imaging compared with CT.. Radiology, 263(2), 569-577.
- Direct visualisation of collateral ventilation in COPD with hyperpolarised gas MRI.. Thorax, 67(7), 613-617. View this article in WRRO
- Intraoperative contrast-enhanced sonography of bowel blood flow: preliminary experience.. J Ultrasound Med, 31(1), 1-5.
- Black blood MRI has diagnostic and prognostic value in the assessment of patients with pulmonary hypertension.. Eur Radiol, 22(3), 695-702.
- Diagnostic accuracy of contrast-enhanced MR angiography and unenhanced proton MR imaging compared with CT pulmonary angiography in chronic thromboembolic pulmonary hypertension.. Eur Radiol, 22(2), 310-317.
- CT pulmonary angiography combined with echocardiography in suspected systemic sclerosis-associated pulmonary arterial hypertension.. Rheumatology (Oxford), 50(8), 1480-1486.
- CT Pulmonary Angiography Combined With Echocardiography In Suspected Systemic Sclerosis-Associated Pulmonary Arterial Hypertension. A60. PULMONARY HYPERTENSION: DIAGNOSIS.
- Black blood MRI has diagnostic and prognostic value in the assessment of patients with pulmonary hypertension. European Radiology, 1-8.
- Rapid lung volumetry using ultrafast dynamic magnetic resonance imaging during forced vital capacity maneuver: correlation with spirometry.. Invest Radiol, 42(1), 37-41.
- Quantitative analysis of regional airways obstruction using dynamic hyperpolarized 3He MRI-preliminary results in children with cystic fibrosis.. J Magn Reson Imaging, 22(3), 420-426.
- Emphysematous changes and normal variation in smokers and COPD patients using diffusion 3He MRI.. Eur J Radiol, 54(3), 352-358.
- Combined helium-3/proton magnetic resonance imaging measurement of ventilated lung volumes in smokers compared to never-smokers.. J Magn Reson Imaging, 21(4), 365-369.
- MRI of helium-3 gas in healthy lungs: posture related variations of alveolar size.. J Magn Reson Imaging, 20(2), 331-335.
- Hyperpolarized 3-helium MR imaging of the lungs: testing the concept of a central production facility.. Eur Radiol, 13(12), 2583-2586.
- Assessment and compensation of susceptibility artifacts in gradient echo MRI of hyperpolarized 3He gas.. Magn Reson Med, 50(2), 417-422.
- Dynamic radial projection MRI of inhaled hyperpolarized 3He gas.. Magn Reson Med, 49(6), 991-997.
- MR imaging of the lungs with hyperpolarized helium-3 gas transported by air.. Phys Med Biol, 47(13), N185-N190.
- Do Hemodynamic Definitions of Chronic Thromboembolic Pulmonary Hypertension Distinguish Between Distinct Phenotypes of Chronic Thromboembolic Pulmonary Disease?. Annals of the American Thoracic Society.
- Deep multi-metric training: the need of multi-metric curve evaluation to avoid weak learning. Neural Computing and Applications.
- Validation of Left Atrial Volume Correction for Single Plane Method on Four-Chamber Cine Cardiac MRI. Tomography, 10(4), 459-470.
- Aortic flow is abnormal in HFpEF. Wellcome Open Research, 8, 577-577.
- Systematic pulmonary embolism follow-up increases diagnostic rates of chronic thromboembolic pulmonary hypertension and identifies less severe disease: results from the ASPIRE Registry. European Respiratory Journal, 2300846-2300846.
- Advancements in cardiac structures segmentation: a comprehensive systematic review of deep learning in CT imaging. Frontiers in Cardiovascular Medicine, 11, 1323461.
- The Left Atrial Area Derived Cardiovascular Magnetic Resonance Left Ventricular Filling Pressure Equation Shows Superiority over Integrated Echocardiography. Medicina, 59(11), 1952-1952.
- Author Correction: Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes. Scientific Reports, 13(1).
- External validation, radiological evaluation, and development of deep learning automatic lung segmentation in contrast-enhanced chest CT. European Radiology.
- Hyperpolarised 129-Xenon Diffusion-weighted MRI for Assessing Lung Microstructure in IPF. ERJ Open Research, 00048-2023.
- Tensor-based multimodal learning for prediction of pulmonary arterial wedge pressure from cardiac MRI. Medical Image Computing and Computer Assisted Intervention – MICCAI 2023: 26th International Conference, Vancouver, October 8-12, 2023, Proceedings.
- Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans. Thorax.
- Non-invasive detection of severe PH in lung disease using magnetic resonance imaging. Frontiers in Cardiovascular Medicine, 10.
- Artificial Intelligence as a Diagnostic Tool in Non-Invasive Imaging in the Assessment of Coronary Artery Disease. Medical Sciences, 11(1), 20-20.
- Medical artificial intelligence is as much social as it is technological. Nature Machine Intelligence.
- The Importance of Mitral Valve Prolapse Doming Volume in the Assessment of Left Ventricular Stroke Volume with Cardiac MRI. Medical Sciences, 11(1), 13-13.
- Cardiovascular magnetic resonance can improve the precision for left ventricular filling pressure assessment. European Heart Journal.
- The reproducibility of manual RV/LV ratio measurement on CT pulmonary angiography. BJR|Open.
- First Genotype-Phenotype Study in TBX4 Syndrome: Gain-of-Function Mutations Causative for Lung Disease. American Journal of Respiratory and Critical Care Medicine.
- Quality of reporting in AI cardiac MRI segmentation studies – A systematic review and recommendations for future studies. Frontiers in Cardiovascular Medicine, 9.
- Quantitative CT Evaluation of Small Pulmonary Vessels Has Functional and Prognostic Value in Pulmonary Hypertension. Radiology.
- Development of a Mortality Prediction Model in Hospitalised SARS-CoV-2 Positive Patients Based on Routine Kidney Biomarkers. International Journal of Molecular Sciences, 23(13), 7260-7260.
- Severe pulmonary hypertension associated with lung disease is characterised by a loss of small pulmonary vessels on quantitative CT. ERJ Open Research, 00503-2021.
- CMR Measures of Left Atrial Volume Index and Right Ventricular Function Have Prognostic Value in Chronic Thromboembolic Pulmonary Hypertension. Frontiers in Medicine, 9.
- Lung MRI with hyperpolarised gases: current & future clinical perspectives. The British Journal of Radiology, 20210207-20210207.
- Repeatability and sensitivity to change of non-invasive end points in PAH: the RESPIRE study. Thorax.
- Feasibility and safety of a telemetric pulmonary artery pressure monitoring system in acute and chronic porcine models of pulmonary hypertension.
- Bayesian Inference Associates Rare KDR Variants with Specific Phenotypes in Pulmonary Arterial Hypertension. Circulation: Genomic and Precision Medicine.
- Meta‐analysis of echocardiographic quantification of left ventricular filling pressure. ESC Heart Failure.
- EXPRESS: Role of Biomarkers in Evaluation, Treatment and Clinical Studies of PAH. Pulmonary Circulation, 204589402095723-204589402095723.
- Maximal Exercise Testing Using the Incremental Shuttle Walking Test Can Be Used to Risk Stratify Patients with Pulmonary Arterial Hypertension. Annals of the American Thoracic Society.
- Left Ventricular Blood Flow Kinetic Energy Assessment by 4D Flow Cardiovascular Magnetic Resonance: A Systematic Review of the Clinical Relevance. Journal of Cardiovascular Development and Disease, 7(3), 37-37.
- The cardiopulmonary unit, 207-215.
- Free breathing lung T1 mapping using image registration in patients with idiopathic pulmonary fibrosis. Magnetic Resonance in Medicine. View this article in WRRO
- Clinical predictors of all‐cause mortality in patients presenting to specialist heart failure clinic with raised NT‐proBNP and no heart failure. ESC Heart Failure. View this article in WRRO
- Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension. European Radiology. View this article in WRRO
- View this article in WRRO Left ventricular blood flow kinetic energy is associated with the six-minute walk test and LV remodelling post valvular intervention in aortic stenosis.. Quantitative imaging in medicine and surgery.
- EXPRESS: Patterns of Thromboembolic Pulmonary Vascular Disease in COVID-19. Pulmonary Circulation, 204589402097919-204589402097919.
- Integrated Cardiopulmonary MRI Assessment of Pulmonary Hypertension. Journal of Magnetic Resonance Imaging.
Chapters
- Noninvasive Estimation of Mean Pulmonary Artery Pressure Using MRI, Computer Models, and Machine Learning, Computational Science – ICCS 2022 (pp. 14-27). Springer International Publishing
- Multimodality Imaging of Pulmonary Hypertension: Prognostication of Therapeutic Outcomes, Medical Radiology (pp. 225-257). Springer International Publishing
- Functional Assessment of Pulmonary Venous Thromboembolism, Medical Radiology (pp. 207-223). Springer International Publishing
- Imaging of the Cardiovascular System, Thorax, and Abdomen CRC Press
Conference proceedings papers
- TabMixer: Noninvasive Estimation of the Mean Pulmonary Artery Pressure via Imaging and Tabular Data Mixing (pp 670-680)
- Optimising Thresholds for the Detection of Pulmonary Hypertension (PH) and Pre-capillary PH Using Automatic Measurement of TRJV on Echocardiography. D109. NOW WE GOT BAD BLOOD: RSF/PC JOINT SESSION ON PULMONARY VASCULAR DISEASE
- 17 Cardiovascular magnetic resonance pressure-volume loops are feasible and have prognostic implications in heart failure: a multicentre UK study. Abstracts
- Improved quantification and prognostication of lung disease on CT in pulmonary hypertension by combining the strengths of deep learning and radiologists: a retrospective multicentre study with external validation. The Royal College of Radiologists Open, Vol. 1 (pp 100096-100096)
- P177 129Xe MRI phenotyping and longitudinal change in patients with asthma and/or COPD and normal pulmonary function tests. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
- P176 Bronchodilator response discordance in patients with asthma and/or COPD assessed by 129Xe-MRI and spirometry. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
- Xe-MRI bronchodilator response to assess disease severity in patients with asthma and/or COPD. Respiratory function technologists/scientists
- Lung physiology and 129Xe MRI data driven clustering of patients with asthma and/or COPD. Clinical respiratory physiology, exercise and functional imaging
- Longitudinal change in lung physiology and 129Xe MRI over 1 year in patients with asthma and/or COPD. Clinical respiratory physiology, exercise and functional imaging
- Interobserver variability of the ATS/ERS/JRS/ALAT diagnostic CT criteria for idiopathic pulmonary fibrosis: a systematic review and meta-analysis. Idiopathic interstitial pneumonias
- Impaired xenon gas transfer observed two years after COVID-19 hospitalisation in patients with signs of interstitial lung disease. Imaging
- Bronchodilator response discordance in patients with asthma and/or COPD using Xe-MRI and spirometry. Respiratory function technologists/scientists
- Artificial Intelligence and Computed Tomography to improve quantification and prognostication of lung disease in precapillary pulmonary hypertension. Pulmonary hypertension
- Age, sex and lung volume dependence of 129Xe MRI gas exchange metrics. Clinical respiratory physiology, exercise and functional imaging
- P10 Defining cardiac MRI change thresholds based on how a patient feels, functions and survives post pulmonary arterial hypertension treatment. Scientific poster abstracts
- 170 Non-invasive assessment of stroke work using cardiac magnetic resonance imaging. Imaging
- 196 The relationship of physical activity, heart rate variability, and night heart rate to established measures of clinical risk in patients with pulmonary arterial hypertension (pah). Stable IHD/Prevention/Hypertension/Lipids
- 158 Remote personalisation of pulmonary arterial hypertension therapy and application of a remote physiological risk score. Heart Failure
- 155 Effect of covid-19 infection and preventive public health measures on haemodynamics, activity and quality of life in patients with pulmonary arterial hypertension. Heart Failure
- 154 Stability of daily physical activity as a remote measure of clinical risk in pulmonary arterial hypertension (pah). Heart Failure
- 153 Differences in physical activity, heart rate and heart variability during clinical worsening events in patients with pulmonary arterial hypertension (pah). Heart Failure
- 138 Physiological detection of clinical worsening and therapeutic response using implanted remote technologies in pah. Heart Failure
- 137 Design and validation of a physiological risk score for pulmonary arterial hypertension (pah). Heart Failure
- BS74 Assessment of fluid status in porcine models of heart failure and pulmonary hypertension. Basic Science
- Quantitative Computed Tomography Lung Parenchymal Features Can Aid in Phenotyping of Group 1 and Group 3 Pulmonary Hypertension. B60. LIFE MOVES FAST! LATE BREAKERS IN PULMONARY HYPERTENSION
- Systematic Follow-up of Patients Following Acute Pulmonary Embolism Identifies High Incidence of Chronic Thromboembolic Pulmonary Hypertension: ASPIRE CTEPH. D106. HOT OFF THE PRESSES! LATE BREAKERS IN PULMONARY VASCULAR DISEASE
- 33 Cardiac MRI thresholds for improvement in pulmonary arterial hypertension. Abstracts
- Heritable pulmonary hypertension: first genotypephenotype study in TBX4 syndrome. EUROPEAN JOURNAL OF HUMAN GENETICS, Vol. 31 (pp 30-31)
- Multimodal Learning for Predicting Mortality in Patients with Pulmonary Arterial Hypertension. 2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 6 December 2022 - 8 December 2022.
- The effect of parenchymal lung disease on patient characteristics and outcome in SSc-PH: Insights from the ASPIRE registry. 13.01 - Pulmonary hypertension
- Prognostic importance of centrilobular ground glass changes in patients with Idiopathic Pulmonary Arterial Hypertension. 13.01 - Pulmonary hypertension
- Physiological assessment of patients with airways dysanapsis using 129Xe MRI. 09.01 - Respiratory function technologists/scientists
- New diagnostic criteria and PVR thresholds in SSc-associated PH: Insights from the ASPIRE registry. 13.01 - Pulmonary hypertension
- Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. 14.02 - Imaging
- Fully automatic deep learning pulmonary hypertension diagnosis using CT pulmonary angiography. 13.01 - Pulmonary hypertension
- Correlation of emPHasis-10 with clinical tests: insights from the ASPIRE registry. 13.01 - Pulmonary hypertension
- 129Xe-MRI and lung function to phenotype ventilation heterogeneity in asthma and/or COPD. 05.02 - Monitoring airway disease
- CMR assessed maladaptive right ventricular remodelling predicts treatment failure in pulmonary arterial hypertension. 13.01 - Pulmonary hypertension
- S93 Systematic follow-up of patients following acute pulmonary embolism is associated with an increased incidence of chronic thromboembolic pulmonary hypertension and less severe disease. ‘The Sixth Sense’ – Prognostication in pulmonary vascular disease
- S92 Remote monitoring enabled evaluation of risk and physiological response to therapeutic escalation and clinical worsening in patients with pulmonary hypertension. ‘The Sixth Sense’ – Prognostication in pulmonary vascular disease
- S91 Remote monitored physical activity is related to established measures of clinical risk in patients with pulmonary arterial hypertension. ‘The Sixth Sense’ – Prognostication in pulmonary vascular disease
- S90 Right ventricular remodelling assessed using cardiac magnetic resonance predicts survival and treatment response in pulmonary arterial hypertension. ‘The Sixth Sense’ – Prognostication in pulmonary vascular disease
- P81 Effect of COVID-19 infection and preventive public health measures on haemodynamics, activity and quality of life in patients with pulmonary arterial hypertension. ‘Contagion’ – The impact of COVID-19
- P41 CT lung parenchymal appearances in chronic thromboembolic pulmonary hypertension (CTEPH). ‘Mission (Im)possible I’ – Pulmonary vascular disease
- P39 Establishing minimally important differences for cardiac MRI endpoints in pulmonary arterial hypertension. ‘Mission (Im)possible I’ – Pulmonary vascular disease
- P37 Correlation of emPHasis-10 with clinical tests: insights from the ASPIRE registry. ‘Mission (Im)possible I’ – Pulmonary vascular disease
- Abstract 13527: The Development of a Remote Pulmonary Arterial Hypertension Risk Score Utilising Remote Monitoring Technology to Monitor Parameters Associated With Mortality in Pulmonary Arterial Hypertension. Circulation, Vol. 146(Suppl_1) (pp a13527-a13527)
- P12 Cardiac findings on body CT: a review of 275,000 CT reports over the past 14 years. Scientific poster presentations
- The quality of reporting in cardiac MRI artificial intelligence segmentation studies - a systematic review. European Heart Journal - Cardiovascular Imaging, Vol. 23(Supplement_2)
- Training and Clinical Validation of Artificial Intelligence Derived Right Atrial Cardiovascular Magnetic Resonance Measurements. A105. YOU CAN PREDICT ALL YOU WANT, BUT EVERYONE KNOWS...
- Physiological Phenotypes of Patients with Asthma and/or COPD Using 129Xe MRI. A99. LOOK AT THAT! NEW FINDINGS FROM LUNG IMAGING
- Lung Subtraction Iodine Mapping in Breathless Patients After COVID-19. C30. LIFE AND LUNGS AFTER COVID: FUNCTIONAL RECOVERY AND OUTCOMES FOLLOWING SARS-CoV2 INFECTION
- Fully Automatic Cardiac and Great Vessel Segmentation on CT Pulmonary Angiography (CTPA) Using Deep Learning. D106. NOE VALLEY: CLOTS, COVID, AND LUNG VASCULAR DISEASES
- Deep Learning Approaches to Classify Lung Parenchymal Disease on CT Images. D106. NOE VALLEY: CLOTS, COVID, AND LUNG VASCULAR DISEASES
- Computed Tomography (CT) Features Are of Diagnostic Utility in Pre Diagnosis Idiopathic Pulmonary Arterial Hypertension (IPAH): A Case Controlled Study. B106. UNION SQUARE: OBSERVATIONAL STUDIES AND CLINICAL TRIALS IN PULMONARY HYPERTENSION
- The Development of a Remote Pulmonary Arterial Hypertension Risk Score Utilising Remote Monitoring Technology to Monitor Parameters Associated With Mortality in Pulmonary Arterial Hypertension. CIRCULATION, Vol. 146
- MRI metric lung parenchyma T1 indicates lung pathology in patients with pulmonary hypertension. Pulmonary hypertension
- A fully automated cardiac magnetic resonance (CMR) assessment improves the evaluation of patients with pulmonary arterial hypertension (PAH). Imaging
- 19 Cardiac magnetic resonance to identify raised left ventricular filling pressure. Abstracts
- 121 Effect of UK COVID-19 public health measures on activity and quality of life in patients with pulmonary arterial hypertension. Heart, Vol. 107(Suppl 1) (pp a91-a91)
- Confidence-quantifying landmark localisation for cardiac MRI. Proceedings of the IEEE International Symposium on Biomedical Imaging (ISBI 2021) (pp 985-988). Virtual conference, 13 April 2021 - 16 April 2021. View this article in WRRO
- Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency: A Randomized Crossover Study (pp a2269-a2269)
- S75 Hyperpolarised 129-xenon MRI in differentiating between fibrotic and inflammatory interstitial lung disease and assessing longitudinal change. Basic science in ILD: what drives progression?
- S93 REPAIR: long-term effects of macitentan on the right ventricle (RV) in pulmonary arterial hypertension (PAH). Pulmonary arterial hypertension: drugs, sox and cytokines
- Abstract 15636: Effect of COVID-19 Public Health Measures on Activity and Quality of Life in Patients With Pulmonary Arterial Hypertension. Circulation, Vol. 142(Suppl_3) View this article in WRRO
- Lung perfusion in pulmonary hypertension – results from the RESPIRE study. Pulmonary hypertension
- REPAIR: long-term effects of macitentan on the right ventricle (RV) in pulmonary arterial hypertension (PAH). Pulmonary hypertension
- New rare variant associations with distinct phenotypes in patients with pulmonary arterial hypertension revealed with Bayesian inference. Pulmonary hypertension
- Cardiac MRI for Prognosis in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis. Imaging
- Sex bias exists in diagnosing pulmonary arterial hypertension via machine learning. Pulmonary hypertension
- Serial cardiac MRI for assessment of cardiac morphology and function in CTEPH patients after PEA or vasodilator therapy. Pulmonary hypertension
- Percent-predicted incremental shuttle walking test distance stratifies risk in pulmonary arterial hypertension. Pulmonary hypertension
- Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension. Pulmonary hypertension
- Cardiac MRI right atrial area measurement thresholds for risk stratification in patients with PAH. Pulmonary hypertension
- Cardiovascular Correlates of Machine-Learned Quantitative Emphysema Subtypes. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study. D76. COPD: CLINICAL STUDIES
- Geodesically Smoothed Tensor Features for Pulmonary Hypertension Prognosis Using the Heart and Surrounding Tissues (pp 253-262) View this article in WRRO
- S125 Quantitative CT and hyperpolarised 129-xenon diffusion-weighted MRI in interstitial lung disease. ‘Under your skin’ – imaging in lung disease
- Diagnostic accuracy of right ventricular trabecular mass measurements as measured on cardiac MRI in suspected pulmonary hypertension. Pulmonary hypertension
- Free breathing lung MRI T1 in patients with idiopathic pulmonary fibrosis and healthy volunteers. Imaging
- Diagnostic and prognostic value of a diagnostic CT regression model in suspected pulmonary hypertension. Pulmonary hypertension
- Repeatability and Sensitivity to change of right ventricular analysis methods using cardiac magnetic resonance imaging in PAH: results from the RESPIRE Study. Imaging
- Longitudinal change in hyperpolarised 129-xenon MR spectroscopy in interstitial lung disease. Imaging
- Imaging functional and microstructural changes in the lungs of children born prematurely. Imaging
- Hyperpolarised 129-xenon diffusion-weighted MRI in interstitial lung disease. Imaging
- Thoracic CT features of patients with BMPR2 mutation: preliminary analysis from the UK National Cohort Study of Idiopathic and Heritable PAH. Pulmonary hypertension
- A prospective study comparing the repeatability and sensitivity to change of non-invasive endpoints in pulmonary arterial hypertension: the RESPIRE study. Pulmonary hypertension
- CT pulmonary angiography-derived right atrial area can risk stratify patients with PAH and PH. Imaging
- Correlations of ventilation heterogeneity and spirometry in asthma; initial experience with hyperpolarised gas MRI in a clinical setting. Imaging
- P165A novel cardiac magnetic resonance imaging model to predict level of mixed venous oxygen levels in pulmonary hypertension. European Heart Journal - Cardiovascular Imaging, Vol. 20(Supplement_2) View this article in WRRO
- P612Averaged, diastolic mitral inflow velocity mapping versus peak velocity for the assessment of left ventricular haemodynamics. European Heart Journal - Cardiovascular Imaging, Vol. 20(Supplement_2) View this article in WRRO
- 284An accurate, multi-parametric cardiovascular magnetic resonance model to predict mean pulmonary artery pressure in pulmonary hypertension. European Heart Journal - Cardiovascular Imaging, Vol. 20(Supplement_2)
- Atrial and Ventricular Axis in COPD and Sub-Phenotypes: The MESA COPD Study. A41. COPD: EPIDEMIOLOGY
- The Incremental Shuttle Walking Test Can Be Used to Risk Stratify Patients with Pulmonary Hypertension as Per the European Respiratory/Cardiac Society Guidelines. A105. GLORY DAYS: THE LATEST CLINICAL RESEARCH IN PAH
- Cardiac MRI: Identifying Thresholds to Predict Mortality in Pulmonary Arterial Hypertension. B27. HEARTBREAKER: HEART FAILURE AND PULMONARY HYPERTENSION
- Averaged, diastolic mitral inflow velocity mapping versus peak velocity for the assessment of left ventricular haemodynamics. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol. 20 (pp 494-495)
- A novel cardiac magnetic resonance imaging model to predict level of mixed venous oxygen levels in pulmonary hypertension. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol. 20 (pp 121-121)
- P16 Identifying partial anomalous pulmonary venous drainage (PAPVD) in patients presenting with suspected pulmonary hypertension (PH). Under pressure: an update in pulmonary vascular disease
- Drug induced interstitial lung disease : a systematic review. European Respiratory Journal, Vol. 52(Suppl 62). Paris, France, 15 September 2018 - 19 September 2018. View this article in WRRO
- Anomalous pulmonary venous drainage (APVD) in patients with suspected pulmonary hypertension (PH). Pulmonary hypertension
- Diagnostic Accuracy and Reproducibility of Unenhanced Computed Tomography in Suspected Pulmonary Hypertension: Pulmonary Arterial and Cardiac Metrics. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Prognostic Value of T1 Mapping in Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Diastolic Septal Angle Is an Independent Predictor of Right Ventricular Insertion Point T1 in Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Cardiac MRI Measured Left Atrial Function Can Identify Patient with Pulmonary Hypertension Due to Left Heart Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Assessment of Suitable Patients and Targets for Lung Volume Reduction with Endobronchial Valves in COPD. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Sinus Rhythm Restoration is Safe and Leads to Clinical Improvement in Patients With Severe Pulmonary Hypertension.. CIRCULATION, Vol. 138
- P183 Impact of patient choice on survival in patients with chronic thromboembolic pulmonary hypertension offered pulmonary endarterectomy. Pulmonary vascular disease: monitoring and managing
- S52 Computed tomography in the diagnosis of left heart disease in patients with suspected pulmonary hypertension. Diagnosing and treating pulmonary vascular disease
- Septal angle on MRI predicts combined pre and post capillary pulmonary hypertension. Thorax, Vol. 72(Suppl 3) (pp A31-A32), 6 December 2017 - 8 December 2017. View this article in WRRO
- P177 Computed tomography diagnostic model for diagnosis of pulmonary hypertension. Pulmonary vascular disease: monitoring and managing
- Three Element Windkessel Model to Non-Invasively Assess PAH Patients: One Year Follow-up (pp 151-154)
- P28 Chronic thromboembolic pulmonary hypertension: long term outcomes in surgical and non-surgical patients. Thorax, Vol. 71(Suppl 3) (pp A98.1-A98)
- S111 Differences in characteristics and outcomes in systemic sclerosis-associated and idiopathic pulmonary arterial hypertension. Thorax, Vol. 71(Suppl 3) (pp A66-A67)
- Non-invasive methods for the estimation of MPAP in COPD patients using cardiac MRI. Thorax, Vol. 71(Suppl 3) (pp A106-A107), 7 December 2016 - 9 December 2016. View this article in WRRO
- Response to treatment assessment in patients with PAH by MRI based computational modelling. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Idiopathic and systemic sclerosis-associated PAH: A comprehensive haemodynamic and radiological comparison. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- MRI derived left atrial volume index predicts treatment response in patients with PAH. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Change in right atrial minimal volume is a prognostic marker in pulmonary arterial hypertension (PAH). 1.3 Imaging
- Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- Idiopathic and systemic sclerosis-associated PAH: A comprehensive haemodynamic and radiological comparison. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- Chronic thrombo-embolic pulmonary hypertension: Long-term outcomes in operated and non-operated patients. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- WS15.2 Multiple breath washout and imaging with 3 He MRI and CT scans to monitor early-stage lung disease in patients with cystic fibrosis. Journal of Cystic Fibrosis, Vol. 15 (pp S24-S25)
- Response to treatment assessment in patients with PAH by MRI based computational modelling. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- P285 Helium Magnetic Resonance Imaging Identifies Regional Ventilation, Perfusion and Microstructure Abnormalities in a Case of “Horse-shoe” Lung. Thorax, Vol. 70(Suppl 3) (pp A222-A223)
- P283 Hyperpolarised Gas MRI – a pathway to Clinical Diagnostic Imaging. Thorax, Vol. 70(Suppl 3) (pp A220.3-A221)
- Improved diagnostic accuracy of MRI in patients with suspected pulmonary hypertension with combined right ventricle and pulmonary artery metrics. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Hyperpolarised gas MR lung imaging – Breaks through to clinical practice. 1.3 Imaging
- Prognostic value of MRI in pulmonary arterial hypertension: Early and late predictors. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Myocardial T1 mapping MRI in patients with PH and age-matched healthy volunteers. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Estimation of mPAP with MRI in pulmonary hypertension subgroups: Comparison with echocardiography. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Diagnosis of pulmonary hypertension from MR image based computational models of pulmonary vascular haemodynamics and decision tree analysis. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Cardiac Hemodynamics In COPD And Emphysema Estimated By Magnetic Resonance Imaging. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 191
- Joint Clustering and Component Analysis of Correspondenceless Point Sets: Application to Cardiac Statistical Modeling (pp 98-109)
- Reusability of Statistical Shape Models for the Segmentation of Severely Abnormal Hearts (pp 257-264)
- S120 Right Ventricular Dysfunction In Pulmonary Hypertension With Combined Pulmonary Fibrosis And Emphysema Syndrome. Thorax, Vol. 69(Suppl 2) (pp A64-A65)
- Automatic, Simultaneous, Non-invasive Measurements of Flow and Area in the Human Pulmonary Arteries from MRI Images (pp 259-264)
- HEPATOCYTE GROWTH FACTOR CONCENTRATION CORRELATES WITH HAEMODYNAMIC SEVERITY IN CONNECTIVE TISSUE DISEASE-ASSOCIATED PULMONARY ARTERIAL HYPERTENSION. THORAX, Vol. 68 (pp A146-A147)
- Analysis of flow vortices in the pulmonary artery of healthy volunteers and patients with pulmonary hypertension. EUROPEAN RESPIRATORY JOURNAL, Vol. 42
- (HE)-H-3 MRI IN YOUNG ADULTS WITH CONGENITAL DIAPHRAGMATIC HERNIA: ALVEOLAR SIZE DIFFERENCES BETWEEN THE IPSI- AND CONTRALATERAL LUNG. INTENSIVE CARE MEDICINE, Vol. 39 (pp S107-S107)
- Non-invasive estimation of pulmonary artery pressure and resistance with CMR imaging: Derivation and prospective validation cohort study. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- He-3 MRI in young adults with congenital diaphragmatic hernia: Alveolar size differences between lungs. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- MRI assessment of right atrial volume and function in pulmonary hypertension. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Prognostic value of ventricular volumes and function in patients with pulmonary hypertension due to chronic obstructive pulmonary disease. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Direct Imaging Of Delayed And Collateral Ventilation In COPD Using Hyperpolarised Gas MRI. D100. THE BIG ROLE OF SMALL AIRWAYS
- Imaging V/Q In Chronic Thromboembolic Pulmonary Hypertension With 3He And 1H MRI. B98. NOVEL APPROACHES TO LUNG IMAGING
- Evaluation Of MR Lung Perfusion In The Assessment Of Chronic Thromboembolic Pulmonary Hypertension. C28. DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION
- Characteristics And Outcomes In Pulmonary Hypertension Associated With COPD/ Emphysema: Results From The ASPIRE Registry. B107. BIOMARKERS AND PREDICTORS OF OUTCOMES IN PULMONARY HYPERTENSION
- MR LV Systolic Eccentricity Index (SEI) Compared To Established Cardiac Mr Parameters For The Diagnosis Of PH: Correlation With Right Heart Catheterization. D26. PULMONARY VASCULAR AND RIGHT HEART PHYSIOLOGY
- ACCURACY OF CONTRAST ENHANCED MR LUNG PERFUSION COMPARED TO PERFUSION SCINTIGRAPHY IN DIAGNOSING CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION. THORAX, Vol. 66 (pp A13-A14)
- TIME-RESOLVED CT PULMONARY ANGIOGRAPHY CONTRAST TRANSIT TIME IN PATIENTS WITH PULMONARY EMBOLISM: A NOVEL FUNCTIONAL CT METRIC OF RIGHT HEART STRAIN?. THORAX, Vol. 66 (pp A12-A12)
- S118 Direct visualisation of collateral ventilation in COPD with hyperpolarised Gas MRI. Thorax, Vol. 66(Suppl 4) (pp A54-A55)
- DIAGNOSTIC UTILITY AND PROGNOSTIC VALUE OF QUANTITATIVE CARDIAC MR INDICES IN PATIENTS WITH SUSPECTED PULMONARY HYPERTENSION. THORAX, Vol. 66 (pp A34-A34)
- Assessment of bowel preparation efficacy using oral barium in 'prepless' CT virtual colonoscopy. GASTROENTEROLOGY, Vol. 126(4) (pp A202-A202)
- Assessment of bowel preparation efficacy using oral barium in "prepless" CT virtual colonoscopy. GUT, Vol. 53 (pp A80-A80)
- Real time imaging of air trapping in COPD with hyperpolarized helium-3 MRI. THORAX, Vol. 58 (pp 73-73)
- Dissolved 129Xe spectroscopy in the lungs of preterm-born children. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- 129Xe MRI patterns of lung function in patients with asthma and/or COPD in the NOVELTY study. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- Multinuclear lung MRI assessment of COVID-19 patients at 6 and 12 weeks after hospital admission. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
Other
- MRI prediction of precapillary pulmonary hypertension according to the sixth world symposium on pulmonary hypertension. Radiology. View this article in WRRO
- Reply to Hou et al.: Can Magnetic Resonance Imaging Effectively Evaluate the Prognosis of Patients with Pulmonary Arterial Hypertension?. American Journal of Respiratory and Critical Care Medicine, 197(5), 676-677.
- Response to: ‘CT assessment for pulmonary hypertension requires systematic assessment of cardiac, vascular and parenchymal signs’ by Marloeset al. Thorax, 70(11), 1087.2-1088.
- 3D contrast-enhanced lung perfusion MRI is an effective screening tool for chronic thromboembolic pulmonary hypertension: results from the ASPIRE Registry.. Thorax, 68(7), 677-678.
Preprints
- Interpretable Multimodal Learning for Cardiovascular Hemodynamics Assessment, arXiv.
- Multimodal Variational Autoencoder for Low-cost Cardiac Hemodynamics Instability Detection, arXiv.
- MeDSLIP: Medical Dual-Stream Language-Image Pre-training for Fine-grained Alignment, arXiv.
- Noninvasive Estimation of Mean Pulmonary Artery Pressure Using MRI, Computer Models, and Machine Learning, arXiv.
- Remote evaluation of risk and physiological response to therapeutic escalation and clinical worsening in patients with pulmonary hypertension, Cold Spring Harbor Laboratory.
- Deep learning automated quantification of lung disease in pulmonary hypertension on CT pulmonary angiography: A preliminary clinical study with external validation, arXiv.
- Tensor-based Multimodal Learning for Prediction of Pulmonary Arterial Wedge Pressure from Cardiac MRI, arXiv.
- Uncertainty Estimation for Heatmap-based Landmark Localization, arXiv.
- DenResCov-19: A deep transfer learning network for robust automatic classification of COVID-19, pneumonia, and tuberculosis from X-rays, arXiv.
- Pulmonary Artery Anatomical Characterization: Relevance to Pulmonary Artery Pressure Sensors, Research Square Platform LLC.
- Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI, Cold Spring Harbor Laboratory.
- First genotype-phenotype study in TBX4 syndrome: gain-of-function mutations causative for lung disease, Cold Spring Harbor Laboratory.
- LUCAS: A highly accurate yet simple risk calculator that predicts survival of COVID-19 patients using rapid routine tests, Cold Spring Harbor Laboratory.
- Feasibility and validation of trans-valvular flow derived by four-dimensional flow cardiovascular magnetic resonance imaging in patients with atrial fibrillation.
- LUCAS: Development and Validation of a Simple Mortality Risk Calculator that Predicts 60-Day Survival of Adult SARS-CoV-2 Positive Patients at Hospital Admission Using Rapid Routine Tests.
- Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension, Cold Spring Harbor Laboratory.
- Teaching interests
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- Undergraduate and post graduate research skills training.
- Radiology teaching for registrars.
- Cluster leader for BMedSci course.
- Professional activities and memberships
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- Member of the Royal College of Physicians 2006.
- Fellow of the Royal College of Radiologists 2010.
- Member of the Pulmonary Vascular Research Institute (PVRI) 2013.
- Associate editor Clinical Radiology 2015.
- PVRI imaging workgroup co-founder with Professor David Kiely 2015.
- Collaborator - Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research 2015.