Dr Erin Cutts
School of Biosciences
Early Career Research Fellow - The Physics of Life and Quantitative Biology
Full contact details
School of Biosciences
Firth Court
Western Bank
Sheffield
S10 2TN
- Profile
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2024-Present: Early Career Research Fellow -The Physics of Life and Quantitative Biology, School of Biosciences, University of Sheffield, Sheffield, UK
2020-2024: Post-doctoral researcher, MRC Laboratory of
Medical Sciences, London, UK
2016-2020: Post-doctoral training fellow, The Institute of
Cancer Research, London, UK
2012-2016: Wellcome Trust Structural Biology D.Phil, the University of Oxford, Oxford, UK
- Research interests
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When cells divide, DNA is packaged into chromosomes to help ensure faithful segregation. To aid this process two families of molecule machine act on the DNA, SMC complexes and Topoisomerases. SMC complexes make DNA loops and can bridge two pieces of DNA, enabling DNA to a spooled up and each copy of the replicated genome to be held together until the division machinery is assembled. Topoisomerase resolve entanglements in the DNA, ensuring it can be divided.
My research focuses on how these enzymes work, both independently and together, and how they are regulated in time and space. I use multidisciplinary approaches, using purified the protein complexes to perform biochemical and single molecule assays, combined with modelling.
- Research group
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I'm always keen to hear from prospective students and post-docs. Current opportunities will be posted here or on my person website.