Professor Simon Heller
Clinical Medicine, School of Medicine and Population Health
Professor of Clinical Diabetes
+44 114 215 9009
Full contact details
Clinical Medicine, School of Medicine and Population Health
Room EU38, E Floor
The Medical School
Beech Hill Road
Sheffield
S10 2RX
- Profile
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For enquiries please contact - ClinMed-Operational@sheffield.ac.uk
- Research interests
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Our groups interests concern clinical research, focussing on clinical investigation involving varied topics with the common theme of immediate relevance to patients with diabetes.
These include aspects of the pathophysiology of hypoglycaemia in diabetes, the contribution of hypoglycaemia to the increased risk of sudden death in young people with Type 1 diabetes (the 'dead in bed' syndrome), the clinical benefits of insulin analogues and trials of complex interventions to enable more effective self-management in people with diabetes.
Our observation that hypoglycaemia unawareness is caused by repeated episodes of hypoglycaemia has led to programmes of unawareness reversal and restoration of hypoglycaemic symptoms in patients with Type 1 diabetes.
Recent research on profound bradycardia during hypoglycaemia in patients with type 2 diabetes and ischaemic heart disease has commanded international attention (Chow et al, Diabetes 2014) and a collaboration between the pharmaceutical industry and our research group has led to recently published guidance to advise the FDA and other agencies of important issue when assessing cardiac electrophysical safety of therapeutic agents in diabetes (Heller et al Am Heart J 2015).
We were the principal investigators for the multi-centre DAFNE trial and lead a national programme of research exploring different facets of the DAFNE education programme.
This has directly led to funded roll-out of the approach by the Department of Health, an appraisal by NICE and recent NICE recommendations that training programmes be available to all patients throughout England and Wales. NIHR awarded a £1.7m 5 year NIHR programme grant, using the DAFNE collaborative (with >30,000 UK trained adults with type 1 diabetes) as a research test-bed.
Following its successful completion (Heller et al, NIHR Journals Lib 2014), the NIHR has recently provided £2..7m programme funding over 5.5 years to continue this work, which has led to improved diabetes care with national and international impact.
Other research has also explored the potential of technology to improve blood glucose control and reduce hypoglycaemia in diabetes and work with the pharmaceutical industry in evaluating the benefit of new insulins (Heller et al Diabetes Care 1999, Heller et al Lancet 2012) and participated in multi-centre trials evaluating technology (Little et al Diabetes Care 2014) and closed loop devices (Thabit et al Lancet Diabetes Endocrinol 2014). Designed and subsequently led the recently completed REPOSE Trial, a multi-centre.£2m HTA funded RCT conducted in England and Scotland, measuring the effectiveness of insulin pump therapy in adults with type 1 diabetes."
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Hyperinsulinaemic–hypoglycaemic glucose clamps in human research: a systematic review of the literature. Diabetologia, 64(4), 727-736. View this article in WRRO
- The DAFNEplus programme for sustained type 1 diabetes self-management: Intervention development using the Behaviour Change Wheel. Diabetic Medicine. View this article in WRRO
- Nocturnal Hypoglycemia in Patients With Diabetes Discharged From ICUs: A Prospective Two-Center Cohort Study*. Critical Care Medicine, 49(4), 636-649.
- Protocol for a cluster randomised controlled trial of the DAFNEplus (Dose Adjustment for Normal Eating) intervention compared with 5x1 DAFNE : a lifelong approach to promote effective self-management in adults with type 1 diabetes. BMJ Open, 11(1). View this article in WRRO
- Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes (EASD) and of the International Society for Pediatric and Adolescent Diabetes (ISPAD) endorsed by JDRF and supported by the American Diabetes Association (ADA). Diabetologia, 63(12), 2501-2520.
- Treatment effects may remain the same even when trial participants differed from the target population. Journal of Clinical Epidemiology. View this article in WRRO
- Risk of severe hypoglycaemia and its impact in type 2 diabetes in DEVOTE. Diabetes, Obesity and Metabolism. View this article in WRRO
- Risk of hypoglycaemia with insulin degludec versus insulin glargine U300 in insulin-treated patients with type 2 diabetes : the randomised, head-to-head CONCLUDE trial. Diabetologia, 63(4), 698-710. View this article in WRRO
- What are the characteristics of the best type 1 diabetes patient education programmes (from diagnosis to long‐term care), do they improve outcomes and what is required to make them more effective?. Diabetic Medicine, 37(4), 545-554.
- Systematic review and meta‐analysis of randomized controlled trials of psychological interventions to improve glycaemic control in children and adults with type 1 diabetes. Diabetic Medicine. View this article in WRRO
- Health research systems in change: the case of ‘Push the Pace’ in the National Institute for Health Research. Health Research Policy and Systems, 17(1). View this article in WRRO
- Redefining hypoglycemia in clinical trials: validation of definitions recently adopted by the American Diabetes Association/European Association for the study of diabetes. Diabetes Care. View this article in WRRO
- Working with insulin, carbohydrates, ketones and exercise to manage diabetes (WICKED) : evaluation of a self‐management course for young people with Type 1 diabetes. Diabetic Medicine. View this article in WRRO
- Clinical targets for continuous glucose monitoring data interpretation : recommendations from the international consensus on time in range. Diabetes Care, 42(8), 1593-1603. View this article in WRRO
- Hypoglycaemia, cardiovascular disease, and mortality in diabetes: epidemiology, pathogenesis, and management. The Lancet Diabetes & Endocrinology, 7(5), 385-396. View this article in WRRO
- Effect of Hypoglycemia on Inflammatory Responses and the Response to Low Dose Endotoxemia in Humans.. Journal of Clinical Endocrinology and Metabolism, 104(4), 1187-1199. View this article in WRRO
- Prolonged Prothrombotic Effects of Antecedent Hypoglycemia in Individuals With Type 2 Diabetes. Diabetes Care, 41(12), 2625-2633. View this article in WRRO
- Experiences of self-management among young adults with type 1 diabetes in the context of a structured education programme: a qualitative study. Diabetic Medicine, 35(11), 1531-1537. View this article in WRRO
- A UK Civil Aviation Authority protocol to allow pilots with insulin-treated diabetes to fly commercial aircraft. The Lancet Diabetes & Endocrinology, 5(9), 677-679.
- Glycaemic outcomes of an Individualised treatMent aPproach for oldER vulnerable patIents: A randomised, controlled stUdy in type 2 diabetes Mellitus (IMPERIUM). Diabetes, Obesity and Metabolism. View this article in WRRO
- The role of structured education in the management of hypoglycaemia. Diabetologia. View this article in WRRO
- Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE). BMJ, 356, ---. View this article in WRRO
- Glucose concentrations of less than 3.0 mmol/l (54 mg/dl) should be reported in clinical trials: a joint position statement of the American Diabetes Association and the Europian Association for the Study of Diabetes. Diabetologia, 60(1), 3-6. View this article in WRRO
- Glucose Concentrations of Less Than 3.0 mmol/L (54 mg/dL) Should Be Reported in Clinical Trials: A Joint Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care, 40(1), 155-157.
- Counter-regulatory hormone responses to hypoglycaemia in people with type 1 diabetes after 4 weeks of treatment with liraglutide adjunct to insulin: a randomized, placebo-controlled, double-blind, crossover trial. Diabetes, Obesity and Metabolism, 17(8), 742-750.
- Follow-up of Blood-Pressure Lowering and Glucose Control in Type 2 Diabetes. New England Journal of Medicine, 371(15), 1392-1406.
- Risk of Cardiac Arrhythmias During Hypoglycemia in Patients With Type 2 Diabetes and Cardiovascular Risk. Diabetes, 63(5), 1738-1747.
- Sustained Reduction in Severe Hypoglycemia in Adults With Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia: 2-Year Follow-up in the HypoCOMPaSS Randomized Clinical Trial. Diabetes Care, dc172682-dc172682.
- Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic analysis, a cluster randomised controlled trial of different models of delivery of an educational intervention and the potential of insulin pumps and additional educator input to improve outcomes. Programme Grants for Applied Research, 2(5), 1-188. View this article in WRRO
Conference proceedings papers
- Reduced risk of hypoglycaemia and lower HbA(1c) with degludec compared to glargine U300 in insulin-treated patients with type 2 diabetes. DIABETOLOGIA, Vol. 62 (pp S47-S47)
- Hypoglycaemia is associated with increased risk of cardiovascular events: results from the EXAMINE trial. DIABETOLOGIA, Vol. 59 (pp S44-S44)
- Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes. The Lancet, Vol. 385 (pp S96-S96)
- Cardiac autonomic regulation during acute experimental hypoglycaemia in type 2 diabetes. DIABETOLOGIA, Vol. 57 (pp S260-S261)
All publications
Journal articles
- Perceptions of adults with type 1 diabetes toward diabetes-specific quality of life measures: a survey-based qualitative exploration. Health and Quality of Life Outcomes, 22(1), 70.
- Relationship Between Sensor-Detected Hypoglycemia and Patient-Reported Hypoglycemia in People With Type 1 and Insulin-Treated Type 2 Diabetes: The Hypo-METRICS Study. Diabetes Care, 47(10), 1769-1777.
- Factors Influencing Physical Activity level in Adults with Type 1 Diabetes: A Cross-Sectional Study. Canadian Journal of Diabetes.
- 833-P: Understanding Attitudes about Basal Insulin—Insights from a Global Survey of People with Type 2 Diabetes. Diabetes, 73(Supplement_1).
- 830-P: No Evidence of Increased Physical Activity–Related Hypoglycemia with Once-Weekly Insulin Icodec vs. Once-Daily Basal Insulin in Type 2 Diabetes—ONWARDS 1–5. Diabetes, 73(Supplement_1).
- The type 1 diabetes grand challenge: The potential for transformative impact from the largest ever investment, £50 million and collaborative thinking across the UK. Diabetic Medicine, 41(7).
- Association between recent exposure to continuous glucose monitoring‐recorded hypoglycaemia and counterregulatory and symptom responses to subsequent controlled hypoglycaemia in people with type 1 diabetes. Diabetes, Obesity and Metabolism.
- Clinical perspectives on the frequency of hypoglycemia in treat-to-target randomized controlled trials comparing basal insulin analogs in type 2 diabetes: a narrative review. BMJ Open Diabetes Research & Care, 12(3), e003930-e003930.
- Ongoing burden and recent trends in severe hospitalised hypoglycaemia events in people with type 1 and type 2 diabetes in Scotland: A nationwide cohort study 2016–2022. Diabetes Research and Clinical Practice, 210, 111642-111642.
- A Cross-sectional Study on the Impact of Educational Status on Physical Activity Level in Danish and English Adults With Type 1 Diabetes. Canadian Journal of Diabetes, 48(3), 204-210.e1.
- Cohort profile: post-hospitalisation COVID-19 (PHOSP-COVID) study. International Journal of Epidemiology. View this article in WRRO
- Long COVID research: an update from the PHOSP-COVID Scientific Summit. The Lancet Respiratory Medicine, 11(11), e93-e94.
- Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study. The Lancet Respiratory Medicine, 11(11), 1003-1019.
- 391-P: Individualized Optimization of Duration and Threshold of Sensor Hypoglycemia Improves Identification of Symptomatic Hypoglycemia Episodes—Hypo-METRICS Study. Diabetes, 72(Supplement_1).
- 390-P: Improving Quality of Life and Self-Efficacy through a Hypoglycemia Management Program—The HARPdoc Randomised Controlled Trial. Diabetes, 72(Supplement_1).
- Psychometric properties of an innovative smartphone application to investigate the daily impact of hypoglycemia in people with type 1 or type 2 diabetes: the Hypo-METRICS app. PLoS ONE, 18(3).
- Referral to the NHS Diabetes Prevention Programme and conversion from nondiabetic hyperglycaemia to type 2 diabetes mellitus in England: a matched cohort analysis. PLoS Medicine, 20(2).
- Integrated safety and efficacy analysis of dasiglucagon for treatment of severe hypoglycaemia in individuals with type 1 diabetes. Diabetes, Obesity and Metabolism.
- Consensus Recommendations for the Use of Automated Insulin Delivery Technologies in Clinical Practice. Endocrine Reviews, 44(2), 254-280.
- Impaired Awareness of Hypoglycemia in Type 1 Diabetes: A Report of An NIDDK Workshop in October 2021. Diabetes Care, 45(12), 2799-2805.
- The impact of hypoglycaemia on quality of life among adults with type 1 diabetes : results from “YourSAY: Hypoglycaemia”. Journal of Diabetes and its Complications. View this article in WRRO
- Hypo-METRICS: Hypoglycaemia - MEasurement, ThResholds and ImpaCtS - A multi-country clinical study to define the optimal threshold and duration of sensor-detected hypoglycaemia that impact the experience of hypoglycaemia, quality of life and health economic outcomes: the study protocol.. Diabet Med, e14892. View this article in WRRO
- The effect of a liberal approach to glucose control in critically ill patients with type 2 diabetes: a multicenter, parallel-group, open-label randomized clinical trial. American Journal of Respiratory and Critical Care Medicine, 206(7), 874-882.
- A parallel randomised controlled trial of the Hypoglycaemia Awareness Restoration Programme for adults with type 1 diabetes and problematic hypoglycaemia despite optimised self-care (HARPdoc).. Nat Commun, 13(1), 2229.
- Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study. The Lancet Respiratory Medicine. View this article in WRRO
- Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19. Thorax, 77(7), 717-720.
- Characteristics of adults with type 1 diabetes and treatment-resistant problematic hypoglycaemia: a baseline analysis from the HARPdoc RCT. Diabetologia.
- Hypoglycemia subtypes in type 1 diabetes : an exploration of the Hypoglycemia Fear Survey-II. Diabetes Care.
- Hypoglycaemia in diabetes. Medicine.
- The impact of hypoglycemia on quality of life and related outcomes in children and adolescents with type 1 diabetes: a systematic review. PLoS ONE, 16(12). View this article in WRRO
- Insulin, the patient, and the health professional. The Lancet, 398(10313), 1785-1786.
- View this article in WRRO Hypoglycaemia combined with mild hypokalaemia reduces the heart rate and causes abnormal pacemaker activity in a computational model of a human sinoatrial cell.. Journal of the Royal Society Interface, 18(184).
- Impact of kidney function on the safety and efficacy of insulin degludec versus insulin glargine U300 in people with type 2 diabetes : a post hoc analysis of the CONCLUDE trial. Diabetes, Obesity and Metabolism.
- Changes in quality of life following hypoglycaemia in adults with type 2 diabetes: A systematic review of longitudinal studies. Diabetic Medicine. View this article in WRRO
- Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.. The Lancet Respiratory Medicine, 9(11), 1275-1287. View this article in WRRO
- ‘Never again will I be carefree’: a qualitative study of the impact of hypoglycemia on quality of life among adults with type 1 diabetes. BMJ Open Diabetes Research & Care, 9(1), e002322-e002322.
- 344-P: Integrated Safety Analysis of Dasiglucagon for Treatment of Severe Hypoglycemia. Diabetes, 70(Supplement_1).
- 191-OR: Similar Hypoglycemia Duration with Once-Weekly Insulin Icodec vs. Insulin Glargine U100 in Insulin Naïve or Experienced Patients with T2D. Diabetes, 70(Supplement_1).
- The Impact of Frailty on the Effectiveness and Safety of Intensive Glucose Control and Blood Pressure-Lowering Therapy for People With Type 2 Diabetes: Results From the ADVANCE Trial.. Diabetes Care.
- Glucose management for exercise using continuous glucose monitoring: should sex and prandial state be additional considerations? Reply to Yardley JE and Sigal RJ [letter]. Diabetologia, 64, 935-938.
- Hyperinsulinaemic–hypoglycaemic glucose clamps in human research: a systematic review of the literature. Diabetologia, 64(4), 727-736. View this article in WRRO
- Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Diabetes and Endocrinology, 9(4), 212-224.
- The impact of hypoglycaemia on quality of life outcomes among adults with type 1 diabetes: A systematic review. Diabetes Research and Clinical Practice, 174, 108752-108752.
- The DAFNEplus programme for sustained type 1 diabetes self-management: Intervention development using the Behaviour Change Wheel. Diabetic Medicine. View this article in WRRO
- Nocturnal Hypoglycemia in Patients With Diabetes Discharged From ICUs: A Prospective Two-Center Cohort Study*. Critical Care Medicine, 49(4), 636-649.
- The suitability of patient-reported outcome measures used to assess the impact of hypoglycaemia on quality of life in people with diabetes: a systematic review using COSMIN methods.. Diabetologia.
- Cardiac arrhythmias and electrophysiologic responses during spontaneous hyperglycaemia in adults with type 1 diabetes mellitus. Diabetes & Metabolism, 101237-101237.
- Long‐term efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes: pooled 52‐week outcomes from the DEPICT‐1 and ‐2 studies outcomes from the DEPICT‐1 and ‐2 studies. Diabetes, Obesity and Metabolism, 23(2), 549-560. View this article in WRRO
- Protocol for a cluster randomised controlled trial of the DAFNEplus (Dose Adjustment for Normal Eating) intervention compared with 5x1 DAFNE : a lifelong approach to promote effective self-management in adults with type 1 diabetes. BMJ Open, 11(1). View this article in WRRO
- Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes (EASD) and of the International Society for Pediatric and Adolescent Diabetes (ISPAD) endorsed by JDRF and supported by the American Diabetes Association (ADA). Diabetologia, 63(12), 2501-2520.
- Epidemiology and determinants of non-diabetic hyperglycaemia and its conversion to type 2 diabetes mellitus, 2000–2015: cohort population study using UK electronic health records. BMJ Open, 10(9), e040201-e040201.
- Rationale and design of the LIBERATES trial : protocol for a randomised controlled trial of flash glucose monitoring for optimisation of glycaemia in individuals with type 2 diabetes and recent myocardial infarction. Diabetes and Vascular Disease Research, 17(5). View this article in WRRO
- Hypoglycemia in patient with type 2 diabetes treated with insulin: it can happen. BMJ Open Diabetes Research & Care, 8(1). View this article in WRRO
- Psychological interventions to improve self-management of type 1 and type 2 diabetes: a systematic review. Health Technology Assessment, 24(28). View this article in WRRO
- 156-OR: Fear of Hypoglycemia in People with Type 1 Diabetes and Problematic Hypoglycaemia: A Mismatch between Worry and Behaviour?. Diabetes, 69(Supplement_1).
- Treatment effects may remain the same even when trial participants differed from the target population. Journal of Clinical Epidemiology. View this article in WRRO
- Psychological interventions to improve glycemic control in adults with type 2 diabetes: a systematic review and meta-analysis. BMJ Open Diabetes Research & Care, 8(1). View this article in WRRO
- Risk of severe hypoglycaemia and its impact in type 2 diabetes in DEVOTE. Diabetes, Obesity and Metabolism. View this article in WRRO
- Risk of hypoglycaemia with insulin degludec versus insulin glargine U300 in insulin-treated patients with type 2 diabetes : the randomised, head-to-head CONCLUDE trial. Diabetologia, 63(4), 698-710. View this article in WRRO
- Evaluating glucose‐lowering treatment in older people with diabetes : lessons from the IMPERIUM trial. Diabetes, Obesity and Metabolism. View this article in WRRO
- What are the characteristics of the best type 1 diabetes patient education programmes (from diagnosis to long‐term care), do they improve outcomes and what is required to make them more effective?. Diabetic Medicine, 37(4), 545-554.
- Influence of cardiac autonomic neuropathy on cardiac repolarisation during incremental adrenaline infusion in type 1 diabetes. Diabetologia. View this article in WRRO
- Systematic review and meta‐analysis of randomized controlled trials of psychological interventions to improve glycaemic control in children and adults with type 1 diabetes. Diabetic Medicine. View this article in WRRO
- Reducing the burden of hypoglycaemia in people with diabetes through increased understanding : design of the Hypoglycaemia REdefining SOLutions for better liVEs (Hypo‐RESOLVE) project. Diabetic Medicine. View this article in WRRO
- The relationship between HbA1c and hypoglycaemia in patients with diabetes treated with insulin degludec versus insulin glargine 100 units/mL. Diabetes, Obesity and Metabolism. View this article in WRRO
- Hypoglycaemia is reduced with use of inhaled Technosphere ® Insulin relative to insulin aspart in type 1 diabetes mellitus. Diabetic Medicine, 37(5), 752-759.
- Predictors of Recurrent Severe Hypoglycemia in Adults With Type 1 Diabetes and Impaired Awareness of Hypoglycemia During the HypoCOMPaSS Study. Diabetes Care, 43(1), 44-52.
- Development of a hypoglycaemia risk score to identify high‐risk individuals with advanced type 2 diabetes in DEVOTE. Diabetes, Obesity and Metabolism, 22(12), 2248-2256.
- Health research systems in change: the case of ‘Push the Pace’ in the National Institute for Health Research. Health Research Policy and Systems, 17(1). View this article in WRRO
- Redefining hypoglycemia in clinical trials: validation of definitions recently adopted by the American Diabetes Association/European Association for the study of diabetes. Diabetes Care. View this article in WRRO
- Working with insulin, carbohydrates, ketones and exercise to manage diabetes (WICKED) : evaluation of a self‐management course for young people with Type 1 diabetes. Diabetic Medicine. View this article in WRRO
- Satisfaction with the Use of Different Technologies for Insulin Delivery and Glucose Monitoring Among Adults with Long-Standing Type 1 Diabetes and Problematic Hypoglycemia: 2-Year Follow-Up in the HypoCOMPaSS Randomized Clinical Trial. Diabetes Technology & Therapeutics, 21(11), 619-626.
- Clinical targets for continuous glucose monitoring data interpretation : recommendations from the international consensus on time in range. Diabetes Care, 42(8), 1593-1603. View this article in WRRO
- Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial. The Lancet Diabetes & Endocrinology, 7(7), 515-527.
- Lower rates of hypoglycaemia in older individuals with type 2 diabetes using insulin degludec versus insulin glargine U100 : results from SWITCH 2. Diabetes, Obesity and Metabolism, 21(7), 1634-1641. View this article in WRRO
- Short‐term cost‐utility of degludec versus glargine U100 for patients with type 2 diabetes at high risk of hypoglycaemia and cardiovascular events: A Canadian setting (DEVOTE 9). Diabetes, Obesity and Metabolism, 21(7), 1706-1714. View this article in WRRO
- Hypoglycaemia Awareness Restoration Programme for People with Type 1 Diabetes and Problematic Hypoglycaemia Persisting Despite Optimised Self-care (HARPdoc): protocol for a group randomised controlled trial of a novel intervention addressing cognitions. BMJ Open, 9(6), e030356-e030356.
- Robert Tattersall, a Diabetes Physician Ahead of His Time. Diabetes Care, 42(6), 1005-1008.
- Hypoglycaemia, cardiovascular disease, and mortality in diabetes: epidemiology, pathogenesis, and management. The Lancet Diabetes & Endocrinology, 7(5), 385-396. View this article in WRRO
- Disruptive illness contexts and liminality in the accounts of young people with type 1 diabetes. Sociology of Health & Illness, 41(7), 1289-1304.
- Effect of Hypoglycemia on Inflammatory Responses and the Response to Low Dose Endotoxemia in Humans.. Journal of Clinical Endocrinology and Metabolism, 104(4), 1187-1199. View this article in WRRO
- Incidence and severity of hypoglycaemia in type 2 diabetes by treatment regimen: a UK multi‐site 12‐month prospective observational study. Diabetes Obesity and Metabolism. View this article in WRRO
- International Consensus on Risk Management of Diabetic Ketoacidosis in Patients With Type 1 Diabetes Treated With Sodium–Glucose Cotransporter (SGLT) Inhibitors. Diabetes Care, 42(6), 1147-1154.
- Hypoglycaemia in diabetes. Medicine, 47(1), 52-58.
- Investigating the Association Between Baseline Characteristics (HbA1c and Body Mass Index) and Clinical Outcomes of Fast-Acting Insulin Aspart in People with Diabetes: A Post Hoc Analysis. Diabetes Therapy, 10(1), 177-188.
- Towards a better understanding of postprandial hyperglycemic episodes in people with diabetes: impact on daily functioning. Current Medical Research and Opinion, 35(3), 525-533.
- Prolonged Prothrombotic Effects of Antecedent Hypoglycemia in Individuals With Type 2 Diabetes. Diabetes Care, 41(12), 2625-2633. View this article in WRRO
- Follow-Up Support for Effective type 1 Diabetes self-management (The FUSED Model): A systematic review and meta-ethnography of the barriers, facilitators and recommendations for sustaining self-management skills after attending a structured education programme. BMC Health Services Research, 18. View this article in WRRO
- Day-to-day fasting self-monitored blood glucose variability is associated with risk of hypoglycaemia in insulin-treated patients with type 1 and type 2 diabetes: a post hoc analysis of the SWITCH trials. Diabetes, Obesity and Metabolism. View this article in WRRO
- Experiences of self-management among young adults with type 1 diabetes in the context of a structured education programme: a qualitative study. Diabetic Medicine, 35(11), 1531-1537. View this article in WRRO
- Average Clinician‐Measured Blood Pressures and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Ischemic Heart Disease in the EXAMINE Trial. Journal of the American Heart Association, 7(20).
- The effect of basal-bolus therapy varies with baseline 1,5-anhydroglucitol level in people with Type 2 diabetes: a post hoc analysis. Diabetic Medicine, 35(9), 1273-1278. View this article in WRRO
- Salbutamol-induced electrophysiological changes show no correlation with electrophysiological changes during hyperinsulinaemic-hypoglycaemic clamp in young people with Type 1 diabetes.. Diabetic Medicine, 35(9), 1264-1272. View this article in WRRO
- Insulin Degludec Has Lower Hypoglycemia Risk than Insulin Glargine U100 in Older People with Type 2 Diabetes (T2D). Diabetes, 67(Supplement_1).
- Effect of once‐weekly semaglutide on the counterregulatory response to hypoglycaemia in people with type 2 diabetes: A randomized, placebo‐controlled, double‐blind, crossover trial. Diabetes, Obesity and Metabolism, 20(11), 2565-2573.
- Reduced Glucose Variability With Glucose-Dependent Versus Glucose-Independent Therapies Despite Similar Glucose Control and Hypoglycemia Rates in a Randomized, Controlled Study of Older Patients With Type 2 Diabetes Mellitus. Journal of Diabetes Science and Technology, 12(6), 1184-1191.
- Evaluating the cost-effectiveness of insulin detemir versus neutral protamine Hagedorn insulin in patients with type 1 or type 2 diabetes in the UK using a short-term modeling approach. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 11, 217-226. View this article in WRRO
- Corrigendum: Recent updates on type 1 diabetes mellitus management for clinicians [Diabetes Metab J 2018;42:3-18] doi 10.4093/dmj.2018.42.1.3. Diabetes and Metabolism Journal, 42(2), 177-177. View this article in WRRO
- Total Cardiovascular Events Analysis of the EXAMINE Trial in Patients with Type 2 Diabetes and Recent Acute Coronary Syndrome. Clinical Cardiology. View this article in WRRO
- Cost-effectiveness of insulin pumps compared with multiple daily injections both provided with structured education for adults with type 1 diabetes: a health economic analysis of the Relative Effectiveness of Pumps over Structured Education (REPOSE) randomised controlled trial. BMJ Open, 8(4). View this article in WRRO
- Alogliptin in Patients with Type 2 Diabetes Receiving Metformin and Sulfonylurea Therapies in the EXAMINE Trial. The American Journal of Medicine, 131(7), 813-819.e5.
- Technology and chronic disease management – Authors' reply. The Lancet Diabetes & Endocrinology, 6(2), 91-92.
- Recent updates on type 1 diabetes mellitus management for clinicians. Diabetes and Metabolism Journal, 42(1), 3-18. View this article in WRRO
- Diabetes structured self-management education programmes: a narrative review and current innovations. The Lancet Diabetes & Endocrinology, 6(2), 130-142.
- International Consensus on Use of Continuous Glucose Monitoring. Diabetes Care, 40(12), 1631-1640.
- High-sensitivity C-reactive Protein, Low-Density Lipoprotein Cholesterol, and Cardiovascular Outcomes in Patients with Type 2 Diabetes in the EXAMINE (Examination of Cardiovascular Outcomes With Alogliptin Versus Standard of Care) Trial.. Diabetes, Obesity and Metabolism. View this article in WRRO
- DEVOTE 3: temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality. Diabetologia. View this article in WRRO
- A UK Civil Aviation Authority protocol to allow pilots with insulin-treated diabetes to fly commercial aircraft. The Lancet Diabetes & Endocrinology, 5(9), 677-679.
- Glycaemic outcomes of an Individualised treatMent aPproach for oldER vulnerable patIents: A randomised, controlled stUdy in type 2 diabetes Mellitus (IMPERIUM). Diabetes, Obesity and Metabolism. View this article in WRRO
- Antecedent Hypoglycemia Does Not Attenuate the Acceleration of Gastric Emptying by Hypoglycemia. The Journal of Clinical Endocrinology & Metabolism, 102(11), 3953-3960.
- The role of structured education in the management of hypoglycaemia. Diabetologia. View this article in WRRO
- Association between mild and severe hypoglycemia in people with type 2 diabetes initiating insulin. Journal of Diabetes and its Complications, 31(6), 1047-1052.
- Diurnal Differences in Risk of Cardiac Arrhythmias During Spontaneous Hypoglycemia in Young People With Type 1 Diabetes. Diabetes Care, 40(5), 655-662. View this article in WRRO
- Rates of hypoglycaemia are lower in patients treated with insulin degludec/liraglutide (IDegLira) than with IDeg or insulin glargine regardless of the hypoglycaemia definition used. Diabetes, Obesity and Metabolism. View this article in WRRO
- Fast-Acting Insulin Aspart Improves Glycemic Control in Basal-Bolus Treatment for Type 1 Diabetes: Results of a 26-Week Multicenter, Active-Controlled, Treat-to-Target, Randomized, Parallel-Group Trial (Onset 1).. Diabetes Care.
- A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial. Health Technology Assessment, 21(20), 1-278. View this article in WRRO
- Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE). BMJ, 356, ---. View this article in WRRO
- Relationship of glycated haemoglobin and reported hypoglycaemia to cardiovascular outcomes in patients with type 2 diabetes and recent acute coronary syndromes: the EXAMINE trial. Diabetes, Obesity and Metabolism. View this article in WRRO
- Staff experiences of closing out a clinical trial involving withdrawal of treatment: qualitative study. Trials, 18. View this article in WRRO
- Glucose concentrations of less than 3.0 mmol/l (54 mg/dl) should be reported in clinical trials: a joint position statement of the American Diabetes Association and the Europian Association for the Study of Diabetes. Diabetologia, 60(1), 3-6. View this article in WRRO
- Glucose Concentrations of Less Than 3.0 mmol/L (54 mg/dL) Should Be Reported in Clinical Trials: A Joint Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care, 40(1), 155-157.
- Projected Long-Term Outcomes in Patients with Type 1 Diabetes Mellitus Treated with Faster-Acting Insulin Aspart Versus Conventional Insulin Aspart in the UK Setting. Value in Health, 19(7), A671-A671.
- Estimation of individual beneficial and adverse effects of intensive glucose control for patients with type 2 diabetes. Diabetologia, 59(12), 2603-2612. View this article in WRRO
- Prandial Options to Advance Basal Insulin Glargine Therapy: Testing Lixisenatide Plus Basal Insulin Versus Insulin Glulisine Either as Basal-Plus or Basal-Bolus in Type 2 Diabetes: The GetGoal Duo-2 Trial. Diabetes Care, 39(8), 1318-1328.
- Managing hypoglycaemia. Best Practice & Research Clinical Endocrinology & Metabolism, 30(3), 413-430. View this article in WRRO
- Cardiovascular Mortality in Patients With Type 2 Diabetes and Recent Acute Coronary Syndromes From the EXAMINE Trial. Diabetes Care, 39(7), 1267-1273.
- Pharmacokinetic Properties of Liraglutide as Adjunct to Insulin in Subjects with Type 1 Diabetes Mellitus. Clinical Pharmacokinetics, 55(11), 1457-1463. View this article in WRRO
- Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON. Diabetes Care, 39(5), 694-700.
- Low–Blood Glucose Avoidance Training Improves Glycemic Variability in Adults With Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia: HypoCOMPaSS Trial. Diabetes Care, 39(4), e56-e58.
- Severe hypoglycaemia in adults with insulin-treated diabetes: impact on healthcare resources. Diabetic Medicine, 33(4), 471-477. View this article in WRRO
- A meta‐analysis of rate ratios for nocturnal confirmed hypoglycaemia with insulin degludec vs. insulin glargine using different definitions for hypoglycaemia. Diabetic Medicine, 33(4), 478-487. View this article in WRRO
- CAD-28: Optimisation de l'utilisation de l'insuline Glargine par l'ajout de lixisénatide prandial vs l'insuline glulisine une fois par jour (GLU-1), ou l'insuline glulisine 3 fois par jour (GLU-3) : GetGoal-Duo2. Diabetes & Metabolism, 42, A31-A31.
- Self-Monitoring of Blood Glucose. Diabetes Technology & Therapeutics, 18(S1).
- Blood glucose monitoring had no impact on distress or self-efficacy in people with non-insulin-treated type 2 diabetes. Evidence Based Medicine, 21(1), 20-20.
- Who gains clinical benefit from using insulin pump therapy? A qualitative study of the perceptions and views of health professionals involved in the Relative Effectiveness of Pumps over MDI and Structured Education (REPOSE) trial. Diabetic Medicine, 33(2), 243-251.
- Effectiveness of the Kids in Control of Food (KICk-OFF) structured education course for 11-16 year olds with Type 1 diabetes. Diabetic Medicine, 33(2), 192-203.
- Characterizing problematic hypoglycaemia: iterative design and preliminary psychometric validation of the Hypoglycaemia Awareness Questionnaire (HypoA-Q). Diabetic Medicine, 33(3), 376-385.
- Uncovering the emotional aspects of working on a clinical trial: a qualitative study of the experiences and views of staff involved in a type 1 diabetes trial. Trials, 16(1). View this article in WRRO
- Accuracy and Performance of continuous Glucose Monitoring with three Closed-Loop Studies with Home Phase under normal Living Conditions. WIENER KLINISCHE WOCHENSCHRIFT, 127, S145-S146.
- Hypoglycaemia, a global cause for concern. Diabetes Research and Clinical Practice, 110(2), 229-232.
- Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes. Journal of Diabetes Science and Technology, 9(6), 1346-1347. View this article in WRRO
- Accuracy of Continuous Glucose Monitoring During Three Closed-Loop Home Studies Under Free-Living Conditions. Diabetes Technology & Therapeutics, 17(11), 801-807. View this article in WRRO
- Incorporating Psychological Predictors of Treatment Response into Health Economic Simulation Models: A Case Study in Type 1 Diabetes. Medical Decision Making, 35(7), 872-887. View this article in WRRO
- Investigating the Evidence of the Real-Life Impact of Acute Hyperglycaemia. Diabetes Therapy, 6(3), 389-393. View this article in WRRO
- Minimizing Hypoglycemia in Diabetes. Diabetes Care, 38(8), 1583-1591.
- Explaining engagement in self-monitoring among participants of the DESMOND Self-monitoring Trial: a qualitative interview study. Family Practice, 32(5), 596-602.
- Developing a theoretical maintenance model for disordered eating in Type 1 diabetes. Diabetic Medicine, 32(12), 1541-1545.
- Modeling predictors of changes in glycemic control and diabetes-specific quality of life amongst adults with type 1 diabetes 1 year after structured education in flexible, intensive insulin therapy. Journal of Behavioral Medicine, 38(5), 817-829.
- An observational study of patient characteristics and mortality following hypoglycemia in the community. BMJ Open Diabetes Research & Care, 3(1). View this article in WRRO
- Unsupervised home use of an overnight closed-loop system over 3-4 weeks: A pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes. Diabetes, Obesity and Metabolism, 17(5), 452-458. View this article in WRRO
- Counter-regulatory hormone responses to hypoglycaemia in people with type 1 diabetes after 4 weeks of treatment with liraglutide adjunct to insulin: a randomized, placebo-controlled, double-blind, crossover trial. Diabetes, Obesity and Metabolism, 17(8), 742-750.
- Holistic Impact of Closed-Loop Technology on People With Type 1 Diabetes. Journal of Diabetes Science and Technology, 9(4), 932-933.
- Self-monitoring of blood glucose versus self-monitoring of urine glucose in adults with newly diagnosed Type 2 diabetes receiving structured education: a cluster randomized controlled trial. Diabetic Medicine, 32(3), 414-422.
- A cluster randomized controlled non-inferiority trial of 5-day Dose Adjustment for Normal Eating (DAFNE) training delivered over 1 week versus 5-day DAFNE training delivered over 5 weeks: the DAFNE 5 × 1-day trial. Diabetic Medicine, 32(3), 391-398. View this article in WRRO
- How standard is standard care? Exploring control group outcomes in behaviour change interventions for young people with type 1 diabetes. Psychology & Health, 30(1), 85-103. View this article in WRRO
- Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting. Diabetic Medicine, 32(5), 601-608.
- Efficacy of theory-based interventions for young people with type 1 diabetes: A systematic review and meta-analysis. British Journal of Health Psychology, 20(2), 428-446.
- Abstract 17295: Cardiovascular Biomarkers and Long-term Outcomes in Patients with Type 2 Diabetes Mellitus Treated with Alogiptin vs. Placebo in the EXAMINE Trial. Circulation, 130(suppl_2).
- Increasing capacity to deliver diabetes self-management education: results of the DESMOND lay educator non-randomized controlled equivalence trial. Diabetic Medicine, 31(11), 1431-1438.
- Follow-up of Blood-Pressure Lowering and Glucose Control in Type 2 Diabetes. New England Journal of Medicine, 371(15), 1392-1406.
- Perceptions and experiences of using automated bolus advisors amongst people with type 1 diabetes: A longitudinal qualitative investigation. Diabetes Research and Clinical Practice, 106(3), 443-450. View this article in WRRO
- Comment on Doyle et al. Closed-Loop Artificial Pancreas Systems: Engineering the Algorithms. Diabetes Care 2014;37:1191–1197. Diabetes Care, 37(10), e226-e227.
- Impact of age, age at diagnosis and duration of diabetes on the risk of macrovascular and microvascular complications and death in type 2 diabetes. Diabetologia, 57(12), 2465-2474.
- The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled trial. BMJ Open, 4(9), e006204-e006204. View this article in WRRO
- Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study. The Lancet Diabetes & Endocrinology, 2(9), 701-709. View this article in WRRO
- Hypoglycaemia in diabetes. Medicine, 42(12), 727-731.
- Substantial reductions in the number of diabetic ketoacidosis and severe hypoglycaemia episodes requiring emergency treatment lead to reduced costs after structured education in adults with Type 1 diabetes. Diabetic Medicine, 31(7), 847-853. View this article in WRRO
- Treatment of Type 2 Diabetes Mellitus in the Older Adult: A Review. Endocrine Practice, 20(7), 722-736.
- Cost effectiveness of group follow-up after structured education for type 1 diabetes: a cluster randomised controlled trial. Trials, 15(1).
- Recovery of Hypoglycemia Awareness in Long-standing Type 1 Diabetes: A Multicenter 2 × 2 Factorial Randomized Controlled Trial Comparing Insulin Pump With Multiple Daily Injections and Continuous With Conventional Glucose Self-monitoring (HypoCOMPaSS). Diabetes Care, 37(8), 2114-2122.
- Risk of Cardiac Arrhythmias During Hypoglycemia in Patients With Type 2 Diabetes and Cardiovascular Risk. Diabetes, 63(5), 1738-1747.
- Cognitive, behavioural and psychological barriers to the prevention of severe hypoglycaemia: A qualitative study of adults with type 1 diabetes. SAGE Open Medicine, 2. View this article in WRRO
- Assessing the cost-effectiveness of Type 1 diabetes interventions: the Sheffield Type 1 Diabetes Policy Model. Diabetic Medicine, 31(4), 477-486.
- P310 L’hypoglycémie liée à l’activité physique apparaît à une fréquence similaire avec l’insuline dégludec et l’insuline glargine. Diabetes & Metabolism, 40, A101-A101.
- A Psychoeducational Program to Restore Hypoglycemia Awareness: The DAFNE-HART Pilot Study: Table 1. Diabetes Care, 37(3), 863-866.
- The face of equipoise - delivering a structured education programme within a randomized controlled trial: qualitative study. Trials, 15(1). View this article in WRRO
- Alogliptin after acute coronary syndrome in patients with type 2 diabetes. Austrian Journal of Clinical Endocrinology and Metabolism, 7(2), 77.
- WICKED: The development and evaluation of a psycho-education programme for young people with type 1 diabetes. Journal of Diabetes Nursing, 18(6), 233-237.
- Stability and predictive utility, over 3 years, of the illness beliefs of individuals recently diagnosed with Type 2 diabetes mellitus. Diabetic Medicine, 31(10), 1260-1263.
- Insulin degludec is not associated with a delayed or diminished response to hypoglycaemia compared with insulin glargine in type 1 diabetes: a double-blind randomised crossover study. Diabetologia, 57(1), 40-49. View this article in WRRO
- Type 1 diabetes patients' experiences of, and need for, social support after attending a structured education programme: a qualitative longitudinal investigation. Journal of Clinical Nursing, 23(19-20), 2919-2927.
- Experiences, Views, and Support Needs of Family Members of People With Hypoglycemia Unawareness: Interview Study: Table 1. Diabetes Care, 37(1), 109-115.
- Experiences of hypoglycaemia unawareness amongst people with Type 1 diabetes: A qualitative investigation. Chronic Illness, 10(3), 180-191.
- Severe hypoglycaemia in type 1 diabetes mellitus: underlying drivers and potential strategies for successful prevention. Diabetes/Metabolism Research and Reviews, 30(3), 175-190.
- Medical and psychological outcomes for young adults with Type 1 diabetes: no improvement despite recent advances in diabetes care. Diabetic Medicine, 31(2), 227-231.
- Intensification of medication and glycaemic control among patients with type 2 diabetes - the ADVANCE trial. Diabetes, Obesity and Metabolism, 16(5), 426-432.
- Diabetes-Oriented Learning Family Intervention (DOLFIN): a feasibility study evaluating an intervention for carers of young persons with Type 1 diabetes. Diabetic Medicine, 31(1), 55-60.
- Restoration of Self-Awareness of Hypoglycemia in Adults With Long-Standing Type 1 Diabetes: Hyperinsulinemic-hypoglycemic clamp substudy results from the HypoCOMPaSS trial. Diabetes Care, 36(12), 4063-4070. View this article in WRRO
- Meta-analysis of insulin aspart versus regular human insulin used in a basal-bolus regimen for the treatment of diabetes mellitus (在基础-餐时糖尿病治疗方案中使用门冬胰岛素与使用常规人胰岛素对照研究的Meta分析). Journal of Diabetes, 5(4), 482-491. View this article in WRRO
- Liraglutide in Combination with Insulin in Type-1-Diabetes: glycemic Effect and Safety in a randomized, double bind Crossover-Study. WIENER KLINISCHE WOCHENSCHRIFT, 125, S14-S14.
- Alogliptin after Acute Coronary Syndrome in Patients with Type 2 Diabetes. New England Journal of Medicine, 369(14), 1327-1335.
- Insulin Pens and New Ways of Insulin Delivery. Diabetes Technology & Therapeutics, 15(S1).
- Type 1 diabetes structured education: what are the core self-management behaviours?. Diabetic Medicine, 30(6), 724-730.
- Once-weekly exenatide versus once- or twice-daily insulin detemir. Diabetes Care, 36(5), 1368-1376. View this article in WRRO
- Linguistic and Psychometric Validation of the Diabetes-Specific Quality-of-Life Scale in U.K. English for Adults With Type 1 Diabetes. Diabetes Care, 36(5), 1117-1125. View this article in WRRO
- Using the Medical Research Council framework to develop a complex intervention to improve delivery of care for young people with Type 1 diabetes. Diabetic Medicine, 30(6), e223-e228.
- The cost-effectiveness of the Dose Adjustment for Normal Eating (DAFNE) structured education programme: an update using the Sheffield Type 1 Diabetes Policy Model. Diabetic Medicine, 30(10), 1236-1244.
- Structured Type 1 Diabetes Education Delivered Within Routine Care: Impact on glycemic control and diabetes-specific quality of life. Diabetes Care, 36(2), 270-272. View this article in WRRO
- Does an intensive self-management structured education course improve outcomes for children and young people with type 1 diabetes? The Kids In Control OF Food (KICk-OFF) cluster-randomised controlled trial protocol: Table 1. BMJ Open, 3(1). View this article in WRRO
- Insulin degludec improves glycaemic control with lower nocturnal hypoglycaemia risk than insulin glargine in basal-bolus treatment with mealtime insulin aspart in Type 1 diabetes (BEGIN®Basal-Bolus Type 1): 2-year results of a randomized clinical trial. Diabetic Medicine, 30(11), 1293-1297.
- Diagnostic Accuracy of an “Amended” Insulin–Glucose Ratio for the Biochemical Diagnosis of Insulinomas. Annals of Internal Medicine, 158(6), 500-500.
- Group follow-up compared to individual clinic visits after structured education for type 1 diabetes: A cluster randomised controlled trial. Diabetes Research and Clinical Practice, 100(1), 29-38.
- Self-treating hypoglycaemia: a longitudinal qualitative investigation of the experiences and views of people with Type 1 diabetes. Diabetic Medicine, 30(2), 209-215.
- Eating problems in adolescents with Type 1 diabetes: a systematic review with meta-analysis. Diabetic Medicine, 30(2), 189-198.
- Prevalence of depression among young people with Type 1 diabetes: a systematic review. Diabetic Medicine, 30(2), 199-208.
- Morphological analysis of T-wave in vectorcardiographic leads system by a bi-Gaussian approach in patients under effect of salbutamol.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 5494-5497.
- Comparison of Optimised MDI versus Pumps with or without Sensors in Severe Hypoglycaemia (the Hypo COMPaSS trial). BMC Endocrine Disorders, 12(1). View this article in WRRO
- The 5x1 DAFNE study protocol: a cluster randomised trial comparing a standard 5 day DAFNE course delivered over 1 week against DAFNE training delivered over 1 day a week for 5 consecutive weeks. BMC Endocrine Disorders, 12(1). View this article in WRRO
- Supporting self-management after attending a structured education programme: a qualitative longitudinal investigation of type 1 diabetes patients’ experiences and views. BMC Public Health, 12. View this article in WRRO
- Improved biomedical and psychological outcomes 1 year after structured education in flexible insulin therapy for people with type 1 diabetes the U.K. DAFNE experience. Diabetes Care, 35(8), 1638-1642. View this article in WRRO
- Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care. BMJ, 344(apr26 2), e2333-e2333.
- Insulin degludec, an ultra-longacting basal insulin, versus insulin glargine in basal-bolus treatment with mealtime insulin aspart in type 1 diabetes (BEGIN Basal-Bolus Type 1): a phase 3, randomised, open-label, treat-to-target non-inferiority trial. The Lancet, 379(9825), 1489-1497.
- Experiences of using blood glucose targets when following an intensive insulin regimen: a qualitative longitudinal investigation involving patients with Type 1 diabetes. Diabetic Medicine, 29(8), 1079-1084.
- Does self monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? the DESMOND SMBG randomised controlled trial protocol. BMC Family Practice, 13. View this article in WRRO
- Working with young adults with Type 1 diabetes: Views of a multidisciplinary care team and implications for service delivery. Diabetic Medicine, 29(5), 677-681.
- Pulmonary function over 2 years in diabetic patients treated with prandial inhaled Technosphere Insulin or usual antidiabetes treatment: a randomized trial. Diabetes, Obesity and Metabolism, 14(2), 163-173.
- Let’s prevent diabetes: study protocol for a cluster randomised controlled trial of an educational intervention in a multi-ethnic UK population with screen detected impaired glucose regulation. Cardiovascular Diabetology, 11(1), 56-56. View this article in WRRO
- Morphological analysis of T-wave in vectorcardiographic leads system by a bi-Gaussian approach in patients under effect of salbutamol. 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
- Patients’ experiences of adjusting insulin doses when implementing flexible intensive insulin therapy: A longitudinal, qualitative investigation. Diabetes Research and Clinical Practice, 98(2), 236-242.
- Association of HbA1c levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds. Diabetologia, 55(3), 636-643.
- Does duration of type 1 diabetes affect the outcomes of structured education?. DIABETOLOGIA, 55, S100-S100.
- Does Glycemic Control Offer Similar Benefits Among Patients With Diabetes in Different Regions of the World?: Results from the ADVANCE trial. Diabetes Care, 34(12), 2491-2495. View this article in WRRO
- Relationship Between Interstitial and Blood Glucose During Hypoglycemia in Subjects with Type 2 Diabetes. Diabetes Technology & Therapeutics, 13(11), 1121-1127.
- Effects of perindopril-indapamide on left ventricular diastolic function and mass in patients with type 2 diabetes: The ADVANCE Echocardiography Substudy. Journal of Hypertension, 29(7), 1439-1447.
- Impaired hypoglycemia awareness. Diabetic Hypoglycemia, 4(1), 1-2.
- Impaired awareness of hypoglycemia: Commentary. Diabetic Hypoglycemia, 4(1), 15.
- How and why do patients with Type 1 diabetes sustain their use of flexible intensive insulin therapy? A qualitative longitudinal investigation of patients’ self-management practices following attendance at a Dose Adjustment for Normal Eating (DAFNE) cours. Diabetic Medicine, 28(5), 532-538.
- Hypoglycemia and Cardiovascular Risks. Diabetes Care, 34(Supplement_2), S132-S137. View this article in WRRO
- Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies. BMJ, 342(apr13 5), d1855-d1855.
- Diabetic hypoglycemia and pregnancy. Diabetic Hypoglycemia, 3(3), 1-2.
- Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: Results from the DESMOND trial. Psychology & Health, 26(3), 321-335.
- Contemporary model for cardiovascular risk prediction in people with type 2 diabetes. European Journal of Cardiovascular Prevention & Rehabilitation, 18(3), 393-398.
- Dose Adjustment for Normal Eating: A qualitative longitudinal exploration of the food and eating practices of type 1 diabetes patients converted to flexible intensive insulin therapy in the UK. Diabetes Research and Clinical Practice, 91(1), 87-93.
- Willingness to Pay for Improvements in Chronic Long-Acting Insulin Therapy in Individuals With Type 1 or Type 2 Diabetes Mellitus. Clinical Therapeutics, 33(9), 1258-1267.
- Understanding information and education gaps among people with type 1 diabetes: A qualitative investigation. Patient Education and Counseling, 83(1), 87-91.
- EXamination of CArdiovascular OutcoMes with AlogliptIN versus Standard of CarE in Patients with Type 2 Diabetes Mellitus and Acute Coronary Syndrome (EXAMINE). A cardiovascular safety study of the dipeptidyl peptidase 4 inhibitor alogliptin in patients with type 2 diabetes with acute coronary syndrome. American Heart Journal.
- EXamination of CArdiovascular OutcoMes with AlogliptIN versus Standard of CarE in Patients with Type 2 Diabetes Mellitus and Acute Coronary Syndrome (EXAMINE). American Heart Journal, 162(4), 620-626.e1.
- Commentary. Diabetic Hypoglycemia, 3(2), 17.
- Long-term biomedical and psychosocial outcomes following DAFNE (Dose Adjustment For Normal Eating) structured education to promote intensive insulin therapy in adults with sub-optimally controlled Type 1 diabetes. Diabetes Research and Clinical Practice, 89(1), 22-29.
- Using dynamic pupillometry as a simple screening tool to detect autonomic neuropathy in patients with diabetes: a pilot study. BIOMED ENG ONLINE, 9. View this article in WRRO
- Prospects for an artificial pancreas. Diabetic Hypoglycemia, 3(1), 1-2.
- Rate-dependent measures of repolarization predict inducibility of ventricular arrhythmias. EP Europace, 12(4), 553-560.
- Hypoglycemia in Type 1 Diabetic Pregnancy: Role of preconception insulin aspart treatment in a randomized study. Diabetes Care, 33(3), 473-477. View this article in WRRO
- Severe Hypoglycemia and Risks of Vascular Events and Death. New England Journal of Medicine, 363(15), 1410-1418.
- The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron-MR Controlled Evaluation (ADVANCE) Study. Diabetologia, 53(5), 821-831.
- Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cost effectiveness analysis. BMJ, 341(aug20 1), c4093-c4093.
- Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial. Diabetes Care, 32(11), 2068-2074. View this article in WRRO
- Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial. Diabetologia, 52(11), 2328-2336.
- A Summary of the ADVANCE Trial. Diabetes Care, 32(suppl_2), S357-S361. View this article in WRRO
- Comparison of insulin detemir and insulin glargine in a basal—bolus regimen, with insulin aspart as the mealtime insulin, in patients with type 1 diabetes: A 52-week, multinational, randomized, open-label, parallel-group, Treat-to-Target noninferiority trial. Clinical Therapeutics, 31(10), 2086-2097. View this article in WRRO
- Frequency and motives of blood glucose self-monitoring in type 1 diabetes. Diabetes Research and Clinical Practice, 85(2), 183-188.
- Comparing hormonal and symptomatic responses to experimental hypoglycaemia in insulin- and sulphonylurea-treated Type 2 diabetes. Diabetic Medicine, 26(7), 665-672.
- Evaluation and Management of Adult Hypoglycemic Disorders: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism, 94(3), 709-728.
- Structured education in type 1 diabetes. The British Journal of Diabetes & Vascular Disease, 9(6), 269-272.
- Hypoglycaemia in Type 2 diabetes. Diabetes Research and Clinical Practice, 82, S108-S111. View this article in WRRO
- Minimizing Hypoglycemia While Maintaining Glycemic Control in Diabetes. Diabetes, 57(12), 3177-3183. View this article in WRRO
- Pilot study of a novel educational programme for 11-16 year olds with type 1 diabetes mellitus: the KICk-OFF course. Archives of Disease in Childhood, 93(11), 927-931.
- Can spectral analysis of heart rate variability detect subclinical autonomic dysfunction as reliably as spontaneous baroreceptor sensitivity?. DIABETOLOGIA, 51, S500-S500.
- Continuous glucose monitoring in patients with insulinoma. Clinical Endocrinology, 68(6), 912-918.
- Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cluster randomised controlled trial. BMJ, 336(7642), 491-495. View this article in WRRO
- Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with Type 2 diabetes: baseline data from the DESMOND randomized controlled trial. Diabetic Medicine, 25(12), 1454-1461.
- The DESMOND educational intervention. Chronic Illness, 4(1), 38-40.
- Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes. New England Journal of Medicine, 358(24), 2560-2572.
- An approach to the assessment of diabetic neuropathy based on dynamic pupillometry.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 557-560.
- Insulin's 85th anniversary—An enduring medical miracle. Diabetes Research and Clinical Practice, 78(2), 149-158.
- Randomized, controlled, single-blind study on use of autologous keratinocytes on a transfer dressing to treat nonhealing diabetic ulcers. Regenerative Medicine, 2(6), 887-902.
- Self monitoring of blood glucose in type 2 diabetes. BMJ, 335(7611), 105-106.
- Risk of hypoglycaemia in types 1 and 2 diabetes: effects of treatment modalities and their duration. Diabetologia, 50(6), 1140-1147.
- Using Continuous Glucose Monitoring to Measure the Frequency of Low Glucose Values When Using Biphasic Insulin Aspart 30 Compared With Biphasic Human Insulin 30: A double-blind crossover study in individuals with type 2 diabetes. Diabetes Care, 30(5), 1044-1048.
- Maternal Glycemic Control and Hypoglycemia in Type 1 Diabetic Pregnancy: A randomized trial of insulin aspart versus human insulin in 322 pregnant women. Diabetes Care, 30(4), 771-776.
- A prospective study of the prevalence of gastrointestinal symptoms in patients with Type 1 diabetes and correlation with diabetes control and quality of life. DIABETIC MEDICINE, 24, 65-65.
- Which health-related quality of life score? A comparison of alternative utility measures in patients with Type 2 diabetes in the ADVANCE trial. Health and Quality of Life Outcomes, 5(1), 21-21. View this article in WRRO
- Gestational diabetes: aetiology and management. Obstetrics, Gynaecology & Reproductive Medicine, 17(12), 345-348.
- An Approach to the Assessment of Diabetic Neuropathy Based on Dynamic Pupillometry. 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
- Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study. Patient Education and Counseling, 64(1-3), 369-377.
- The development of an innovative education curriculum for 11?16 yr old children with type 1 diabetes mellitus (T1DM). Pediatric Diabetes, 7(6), 322-328.
- Insulin detemir lowers the risk of hypoglycaemia and provides more consistent plasma glucose levels compared with NPH insulin in Type 1 diabetes. Diabetic Medicine, 23(7), 729-735.
- Aircrew and type 1 diabetes mellitus. Aviation Space and Environmental Medicine, 77(4), 456-458.
- A knowledge-based electrocardiogram-monitoring system for detection of the onset of nocturnal hypoglycaemia in type 1 diabetic patients. Computers in Cardiology, 33, 5-8.
- Hypoglycaemia in diabetes. Medicine, 34(3), 107-110.
- Surgery in patients with diabetes. Medicine, 34(2), 80-82.
- The effect of pramlintide on hormonal, metabolic or symptomatic responses to insulin-induced hypoglycaemia in patients with type 1 diabetes. Diabetes, Obesity and Metabolism, 7(5), 504-516.
- Home blood glucose monitoring in Type 2 diabetes. Diabetic Medicine, 22(s3), 11-13.
- Effect of atenolol on QTc interval lengthening during hypoglycaemia in type 1 diabetes. Diabetologia, 48(7), 1269-1272.
- Adolescents’ and their parents’ views on the acceptability and design of a new diabetes education programme: a focus group analysis. Child: Care, Health and Development, 31(3), 283-289.
- Thoughts of a departing Editor. Diabetic Medicine, 21(12), 1261-1262.
- Severe hypoglycaemia in 1076 adult patients with type 1 diabetes: influence of risk markers and selection. Diabetes/Metabolism Research and Reviews, 20(6), 479-486.
- Prolonged cardiac repolarisation during spontaneous nocturnal hypoglycaemia in children and adolescents with type 1 diabetes. Diabetologia, 47(11), 1940-1947.
- A clinical research network in diabetes for the UK. Diabetic Medicine, 21(10), 1061-1063.
- Nateglinide alone or with metformin safely improves glycaemia to target in patients up to an age of 84. Diabetes, Obesity and Metabolism, 6(5), 344-352.
- Effect of pramlintide on symptom, catecholamine, and glucagon responses to hypoglycemia in healthy subjects. Metabolism, 53(9), 1227-1232.
- Weight gain during insulin therapy in patients with type 2 diabetes mellitus. Diabetes Research and Clinical Practice, 65, S23-S27.
- A new autologous keratinocyte dressing treatment for non-healing diabetic neuropathic foot ulcers. Diabetic Medicine, 21(7), 786-789.
- Hypoglycaemia with insulin aspart: a double-blind, randomised, crossover trial in subjects with Type 1 diabetes. Diabetic Medicine, 21(7), 769-775.
- Influence of Autonomic Neuropathy on QTc Interval Lengthening During Hypoglycemia in Type 1 Diabetes. Diabetes, 53(6), 1535-1542.
- Changes in cardiac repolarization during clinical episodes of nocturnal hypoglycaemia in adults with Type 1 diabetes. Diabetologia, 47(2), 312-315.
- Cost-effectiveness of flexible intensive insulin management to enable dietary freedom in people with Type 1 diabetes in the UK. Diabetic Medicine, 21(5), 460-467.
- Clinical evaluation of a plasma polymer surface for culture and transfer of keratinocytes for chronic wounds. Transactions - 7th World Biomaterials Congress, 1068.
- Analysis of 18F-FDG uptake patterns in PET for diagnosis of septic and aseptic loosening after total hip arthroplasty. Nuklearmedizin, 42(06), 234-239.
- Insulin lispro: a useful advance in insulin therapy. Expert Opinion on Pharmacotherapy, 4(8), 1407-1416.
- Mechanisms of Abnormal Cardiac Repolarization During Insulin-Induced Hypoglycemia. Diabetes, 52(6), 1469-1474.
- Training in flexible intensive insulin management improved glycaemic control and quality of life in type 1 diabetes. Evidence-Based Medicine, 8(3), 80-80.
- The National Service Framework for Diabetes: a glass half empty or half full?. Diabetic Medicine, 20(3), 173-174.
- Effects of adrenaline and potassium on QTc interval and QT dispersion in man. European Journal of Clinical Investigation, 33(2), 93-98.
- Cardiac arrhythmias in hypoglycaemia. Diabetes, Nutrition and Metabolism - Clinical and Experimental, 15(6), 461-467.
- Training in flexible, intensive insulin management to enable dietary freedom in people with type 1 diabetes: dose adjustment for normal eating (DAFNE) randomised controlled trial. BMJ, 325(7367), 746-746.
- What we know about counterregulation in Type 2 diabetes. Diabetes, Nutrition and Metabolism - Clinical and Experimental, 15(5), 372-376.
- Reducing hypoglycaemia with insulin analogues. International Journal of Obesity, 26(S3), S31-S36.
- Abnormalities of the electrocardiogram during hypoglycaemia: The cause of the dead in bed syndrome?. International Journal of Clinical Practice, Supplement(129), 27-32.
- Acute changes of bone turnover and PTH induced by insulin and glucose: Euglycemic and hypoglycemic hyperinsulinemic clamp studies. Journal of Clinical Endocrinology and Metabolism, 87(7), 3324-3329.
- Acute Changes of Bone Turnover and PTH Induced by Insulin and Glucose: Euglycemic and Hypoglycemic Hyperinsulinemic Clamp Studies. Journal of Clinical Endocrinology & Metabolism, 87(7), 3324-3329.
- Mistaken priorities in diabetes research. Diabetic Medicine, 19(4), 263-264.
- Does insulin lispro preserve the physiological defences to hypoglycaemia during intensive insulin therapy with a conventional basal bolus regimen?. Diabetes, Obesity and Metabolism, 4(2), 106-112.
- Insulin aspart: promising early results borne out in clinical practice. Expert Opinion on Pharmacotherapy, 3(2), 183-195.
- Surgery in Patients with Diabetes. Medicine, 30(2), 66-67.
- Hypoglycaemia in Diabetes. Medicine, 30(2), 54-57.
- Insulin Analogues. Current Medical Research and Opinion, 18(sup1), s40-s47.
- New electronic horizons for Diabetic Medicine. Diabetic Medicine, 18(9), 689-689.
- Acute hypoglycemia suppresses parathyroid hormone and bone turnover markers: An insulin clamp study.. JOURNAL OF BONE AND MINERAL RESEARCH, 16, S403-S403.
- Comparison of thyroid function in pregnant and non-pregnant Asian and western Caucasian women. Clinica Chimica Acta, 308(1-2), 91-98.
- Current perspectives and future treatment options in type 2 diabetes: Proceedings of a symposium, 20-22 October 2000, Dublin, Ireland: Chairman's introduction and commentary. Practical Diabetes International, 18(SUPPL.).
- Reflections of a new Editor. Diabetic Medicine, 17(12), 819-819.
- Effect of intravenous adrenaline on cardiac repolarization in healthy males - Increases in corrected QT duration occur independently of hypokalaemia. JOURNAL OF PHYSIOLOGY-LONDON, 528P, 42P-42P.
- Chromium supplementation improves insulin resistance in patients with Type 2 diabetes mellitus. Diabetic Medicine, 17(9), 684-685.
- Severe hypoglycaemia in unselected patients with type 1 diabetes: A cross-sectional multicentre survey. DIABETOLOGIA, 43, A194-A194.
- Does the choice of treatment for type 2 diabetes affect the physiological response to hypoglycemia?. Diabetes Care, 23(7), 1022-1023.
- New clothes for Diabetic Medicine. Diabetic Medicine, 17(6), 413-413.
- The quality of clinical care in diabetes in Britain - could do better. Diabetic Medicine, 17(5), 335-335.
- Measurement of high resolution ECG QT interval during controlled euglycaemia and hypoglycaemia. Physiological Measurement, 21(2), 295-303.
- Hypoglycaemia and associated hypokalaemia in diabetes: mechanisms, clinical implications and prevention. Diabetes, Obesity and Metabolism, 2(2), 75-82.
- The last editor of Diabetic Medicine?. Diabetic Medicine, 17(1), 1-1.
- Association of elevated insulin-like growth factor binding protein-1 with insulin resistance in hyperthyroidism. Clinical Endocrinology, 52(2), 187-187.
- Sudden cardiac death in young people with diabetes. CME Bulletin Endocrinology and Diabetes, 3(1), 4-7.
- Effect of the fast-acting insulin analog lispro on the risk of nocturnal hypoglycemia during intensified insulin therapy. U.K. Lispro Study Group. Diabetes Care, 22(10), 1607-1611.
- Dead in bed. Diabetic Medicine, 16(9), 782-785.
- Sudden death in young patients with Type 1 diabetes: a consequence of disease, treatment or both?. Diabetic Medicine, 16(8), 623-625.
- A comparison of the metabolic and cardiac electrophysiophysiological changes during experimental and clinical hypoglycaemia.. DIABETOLOGIA, 42, A71-A71.
- Soluble insulin and the rapid -acting analogue insulin aspart have similar effects upon ventricular repolarization.. DIABETOLOGIA, 42, A237-A237.
- Chromium Homeostasis in Patients with Type II (NIDDM) Diabetes. Journal of Trace Elements in Medicine and Biology, 13(1-2), 57-61.
- Diabetic hypoglycaemia. Best Practice & Research Clinical Endocrinology & Metabolism, 13(2), 279-294.
- The Shindig project: some lessons in implementing the GEHR architecture. Health Informatics Journal, 5(4), 200-204.
- Glucose Metabolism, 4-26.
- Population-based modeling to demonstrate extrapancreatic effects of tolbutamide. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 274(4), E758-E771.
- Population-based modeling to demonstrate extrapancreatic effects of tolbutamide. American Journal of Physiology-Endocrinology and Metabolism, 274(4), E758-E771.
- Analysis of antibodies against components of the autonomic nervous system in diabetes mellitus. QJM, 90(9), 577-585.
- Altered ventricular repolarization during hypoglycaemia in patients with diabetes. Diabetic Medicine, 14(8), 648-654.
- Preservation of Physiological Responses to Hypoglycemia 2 Days After Antecedent Hypoglycemia in Patients With IDDM. Diabetes Care, 20(8), 1293-1298.
- Further evidence for a high incidence of nocturnal hypoglycaemia in IDDM: no effect of dose for dose transfer between human and porcine insulins. Diabetic Medicine, 14(6), 442-448.
- Diabetes in the Undergraduate Medical Curriculum: A Response to ‘Tomorrow's’ Doctors'. Diabetic Medicine, 14(4), 275-278.
- The Use of Tolbutamide-Induced Hypoglycemia to Examine the Intraislet Role of Insulin in Mediating Glucagon Release in Normal Humans. Journal of Clinical Endocrinology & Metabolism, 82(5), 1458-1461.
- The insulinergic effect of tolbutamide during euglycaemic clamp in non-diabetic subjects: Pharmacokinetic-pharmacodynamic modelling. British Journal of Clinical Pharmacology, 41(5).
- A portable system for monitoring physiological responses to hypoglycaemia. Journal of Medical Engineering & Technology, 20(6), 196-202.
- Training and professional development in diabetes care. Diabetic Medicine, 13(SUPPL. 4).
- Training and professional development in diabetes care.. Diabet Med, 13(9 Suppl 4), S65-S76.
- Abnormalities on the ECG during spontaneous overnight hypoglycaemia in patients with type 1 diabetes. DIABETOLOGIA, 39, 824-824.
- In search of a hypoglycaemic alarm. DIABETOLOGIA, 39, 832-832.
- Impaired peripheral physiological responses to hypoglycaemia in insulin treated type II diabetes. DIABETOLOGIA, 39, 243-243.
- Fasting insulin predicts the acute insulinergic effect of tolbutamide, which is not related to hypoglycaemic effect.. DIABETOLOGIA, 39, 870-870.
- Tolbutamide enhances glucose effectiveness following acute administration in non-diabetic subjects.. DIABETOLOGIA, 39, 869-869.
- Experimentally induced hypoglycaemia. The Lancet, 348(9019), 60-61.
- Similar Physiological and Symptomatic Responses to Sulphonylurea and Insulin Induced Hypoglycaemia in Normal Subjects. Diabetic Medicine, 13(7), 634-641.
- The Measurement of Cognitive Function During Acute Hypoglycaemia: Experimental Limitations and Their Effect on the Study of Hypoglycaemia Unawareness. Diabetic Medicine, 13(7), 607-615.
- Asian women are at increased risk of gestational thyrotoxicosis. Journal of Clinical Endocrinology & Metabolism, 81(3), 1160-1163.
- Prolonged but partial impairment of the hypoglycaemic physiological response following short-term hypoglycaemia in normal subjects. Diabetologia, 38(10), 1183-1190.
- Prolonged but partial impairment of the hypoglycaemic physiological response following short-term hypoglycaemia in normal subjects. Diabetologia, 38(10), 1183-1190.
- QTC INTERVAL PROLONGATION DURING HYPOGLYCEMIA IN PATIENTS WITH IDDM - A POSSIBLE MECHANISM OF SUDDEN-DEATH. DIABETOLOGIA, 38, A18-A18.
- PHYSIOLOGICAL-RESPONSES TO HYPOGLYCEMIA ARE NOT REDUCED 2 DAYS AFTER ANTECEDENT HYPOGLYCEMIA IN IDDM. DIABETOLOGIA, 38, A18-A18.
- Unreliability of reports of hypoglycaemia by diabetic patients. BMJ, 310(6977), 440-440.
- HYPOGLYCEMIA ATTENUATES PHYSIOLOGICAL-RESPONSES TO FURTHER HYPOGLYCEMIA UP TO ONE, WEEK LATER. DIABETOLOGIA, 37, A165-A165.
- Neurologic consequences of hypoglycemia and pathogenic mechanisms involved in diabetic neuropathy. Current Opinion in Neurology and Neurosurgery, 6(3), 423-428.
- Brittle diabetes in the young. Practitioner, 236(1521), 1126-1129.
- Book reviews. Diabetologia, 35(10), 1009-1010.
- A multicentre trial of the aldose-reductase inhibitor tolrestat, in patients with symptomatic diabetic peripheral neuropathy. Diabete et Metabolisme, 18(1), 14-20.
- Hypoinsulinemia is not critical to glucose recovery from hypoglycemia in humans. American Journal of Physiology-Endocrinology and Metabolism, 261(1), E41-E48.
- Physiological disturbances in hypoglycaemia: Effect on subjective awareness. Clinical Science, 81(1), 1-9.
- Increased symptoms of hypoglycaemia in the standing position in insulin-dependent diabetes mellitus. Clinical Science, 80(6), 583-586.
- Course of brittle diabetes: 12 year follow up.. BMJ, 302(6787), 1240-1243.
- Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans. Diabetes, 40(2), 223-226.
- Reduced Neuroendocrine and Symptomatic Responses to Subsequent Hypoglycemia After 1 Episode of Hypoglycemia in Nondiabetic Humans. Diabetes, 40(2), 223-226.
- Double-Blind Evaluation of Efficacy and Tolerability of Metformin in NIDDM. Diabetes Care, 14(4), 342-344.
- Beta-adrenoceptor blockade and hypoglycaemia. A randomised, double- blind, placebo controlled comparison of metoprolol CR, atenolol and propranolol LA in normal subjects.. British Journal of Clinical Pharmacology, 29(6), 685-693.
- Alcohol causes hypoglycaemic unawareness in healthy volunteers and patients with Type 1 (insulin-dependent) diabetes. Diabetologia, 33(4), 216-221.
- Group Education for Obese Patients with Type 2 Diabetes: Greater Success at Less Cost. Diabetic Medicine, 5(6), 552-556.
- Optic Disc Swelling in Young Diabetic Patients: a Diagnostic Dilemma. Diabetic Medicine, 4(3), 260-264.
- Counterregulation in Type 2 (non-insulin-dependent) diabetes mellitus. Normal endocrine and glycaemic responses, up to ten years after diagnosis. Diabetologia, 30(12), 924-929.
- INFLUENCE OF SYMPATHETIC NERVOUS SYSTEM ON HYPOGLYCAEMIC WARNING SYMPTOMS. The Lancet, 330(8555), 359-363.
- Starting Insulin Treatment as an Outpatient. JAMA, 256(7), 877-877.
- Starting insulin treatment as an outpatient. Report of 100 consecutive patients followed up for at least one year. JAMA: The Journal of the American Medical Association, 256(7), 877-880.
- Renal handling of calcium and sodium in metastatic and non-metastatic malignancy.. BMJ, 292(6520), 583-586.
- Quantitation of the renal effect of calcitonin in the hypercalcaemia of malignancy. European Journal of Clinical Pharmacology, 31(1), 27-31.
- MICROALBUMINURIA AND RETINOPATHY. The Lancet, 326(8448), 212-212.
- Insulin Dependence: Problems with the Classification of 100 Consecutive Patients. Diabetic Medicine, 2(3), 167-172.
- The chemical information system and spectral databases. Journal of Chemical Information and Modeling, 25(3), 224-231.
- Vertebral and Paravertebral Sepsis in Diabetes: An Easily Missed Cause of Backache. Diabetic Medicine, 2(5), 395-397.
- Seven Years Experience of Home Management in Pregnancy in Women with Insulin-dependent Diabetes. Diabetic Medicine, 1(3), 199-204.
- Non-steroidal anti-inflammatory drugs and benign oesophageal stricture.. BMJ, 285(6336), 167-168.
- Acceptability and psychometric properties of four scales assessing the impact of Type 2 diabetes on quality of life—Results of ‘
YourSAY : Quality of Life’. Diabetic Medicine. - The impact of hypoglycaemia on daily functioning among adults with diabetes: a prospective observational study using the Hypo-METRICS app. Diabetologia.
- Estimating risk of consequences following hypoglycaemia exposure using the Hypo-RESOLVE cohort: a secondary analysis of pooled data from insulin clinical trials. Diabetologia.
- From educator to facilitator: Healthcare professionals' experiences of, and views about, delivering a type 1 diabetes structured education programme (
DAFNEplus ) informed by behavioural science. Diabetic Medicine. - Sustaining the benefits of structured education: Participants' experiences of receiving structured individual support during a programme (
DAFNE plus) informed by behavioural science. Diabetic Medicine. - Risk factors and prediction of hypoglycaemia using the Hypo-RESOLVE cohort: a secondary analysis of pooled data from insulin clinical trials. Diabetologia.
- Development of a new health-related quality of life measure for people with diabetes who experience hypoglycaemia: the Hypo-RESOLVE QoL. Diabetologia.
- Associations of clinical, psychological, and sociodemographic characteristics and ecological momentary assessment completion in the 10‐week
Hypo‐METRICS study: HypoglycaemiaMEasurements ThResholds andImpaCtS . Diabetic Medicine. - Diabetic autonomic neuropathy does not impede improvement in hypoglycaemia awareness in adults: Sub‐study results from the
HypoCOMPaSS trial. Diabetic Medicine. - Mitigating Severe Hypoglycemia in Users of Advanced Diabetes Technologies: Impaired Awareness of Hypoglycemia and Unhelpful Hypoglycemia Beliefs as Targets for Interventions. Diabetes Technology & Therapeutics.
- Associations between hypoglycemia awareness status and symptoms of hypoglycemia among adults with type 1 or insulin-treated type 2 diabetes using the Hypo-METRICS smartphone application. Diabetes Technology & Therapeutics.
- Cost‐effectiveness of a Novel Hypoglycaemia Programme: The ‘HARPdoc vs BGAT’ RCT. Diabetic Medicine.
- A comparison of the rates of clock-based nocturnal hypoglycemia and hypoglycemia whilst asleep among people living with diabetes: findings from the Hypo-METRICS study. Diabetes Technology & Therapeutics.
- Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study. Acta Diabetologica.
- Participants' experiences of attending a structured education course (DAFNEplus) informed by behavioural science. Diabetic Medicine.
- Assessing the Content Validity, Acceptability, and Feasibility of the Hypo-METRICS App: Survey and Interview Study. JMIR Diabetes, 8, e42100-e42100.
- Diabetes prevention at scale: narrative review of findings and lessons from the
DIPLOMA evaluation of theNHS Diabetes Prevention Programme in England. Diabetic Medicine. - CONTINUOUS GLUCOSE MONITORING BY INSULIN-TREATED PILOTS FLYING COMMERCIAL AIRCRAFT WITHIN THE ARA.MED.330 DIABETES PROTOCOL: A PRELIMINARY FEASIBILITY STUDY. Diabetes Technology & Therapeutics.
- Multicenter Randomized Trial of Intermittently Scanned Continuous Glucose Monitoring Versus Self-Monitoring of Blood Glucose in Individuals With Type 2 Diabetes and Recent-Onset Acute Myocardial Infarction: Results of the LIBERATES Trial. Diabetes Care.
- Producing a preference‐based quality of life measure to quantify the impact of hypoglycaemia on people living with diabetes: a mixed‐methods research protocol. Diabetic Medicine.
- Breaking Barriers With Basal Insulin Biosimilars in Type 2 Diabetes. Clinical Diabetes.
- Consistent Effects of Hypoglycemia on Cognitive Function in People With or Without Diabetes. Diabetes Care.
- Glycaemic thresholds for counterregulatory hormone and symptom responses to hypoglycaemia in people with and without type 1 diabetes: a systematic review. Diabetologia.
- The impact of hypoglycaemia in children and adolescents with type 1 diabetes on parental quality of life and related outcomes: A systematic review. Pediatric Diabetes.
- A higher non-severe hypoglycaemia rate is associated with an increased risk of subsequent severe hypoglycaemia and major adverse cardiovascular events in individuals with type 2 diabetes in the LEADER study. Diabetologia.
- Optimising the use of technology to support people with diabetes: research recommendations from Diabetes UK’s 2019 diabetes and technology workshop. Diabetic Medicine.
- A comparison of the acceptability and psychometric properties of scales assessing the impact of type 1 diabetes on quality of life – Results of ‘YourSAY: Quality of Life’. Diabetic Medicine.
- Sustained type 1 diabetes self‐management: Specifying the behaviours involved and their influences. Diabetic Medicine.
- Glucose management for exercise using continuous glucose monitoring ( CGM ) and intermittently scanned CGM ( isCGM ) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes ( EASD ) and of the International Society for Pediatric and Adolescent Diabetes ( ISPAD ) endorsed by JDRF and supported by the American Diabetes Association ( ADA ). Pediatric Diabetes.
- How has psycho‐behavioural research advanced our understanding of hypoglycaemia in type 1 diabetes?. Diabetic Medicine.
- Sustained Reduction in Severe Hypoglycemia in Adults With Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia: 2-Year Follow-up in the HypoCOMPaSS Randomized Clinical Trial. Diabetes Care, dc172682-dc172682.
- Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic analysis, a cluster randomised controlled trial of different models of delivery of an educational intervention and the potential of insulin pumps and additional educator input to improve outcomes. Programme Grants for Applied Research, 2(5), 1-188. View this article in WRRO
- Frequency of biochemical hypoglycaemia in adults with Type 1 diabetes with and without impaired awareness of hypoglycaemia: no identifiable differences using continuous glucose monitoring. Diabetic Medicine, 27(6), 666-672.
- Depressive symptoms in the first year from diagnosis of Type 2 diabetes: results from the DESMOND trial. Diabetic Medicine, 27(8), 965-967.
- ‘Educator talk’ and patient change: some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial. Diabetic Medicine, 25(9), 1117-1120.
- Editorial. Diabetic Medicine, 21(9), 961-961.
- Classification of SAECG by autoregressive modelling and neural networks. 2004 IEEE Africon. 7th Africon Conference in Africa (IEEE Cat. No.04CH37590).
- Comparative effect of human soluble insulin and insulin aspart upon hypoglycaemia-induced alterations in cardiac repolarization. British Journal of Clinical Pharmacology, 55(3), 246-251.
- An Evaluation of the Safety of Pilots With Insulin-Treated Diabetes in Europe Flying Commercial and Noncommercial Aircraft. Diabetes Care, dc200277-dc200277.
- A systematic review of interventions to improve outcomes for young adults with Type 1 diabetes.. Diabet Med. View this article in WRRO
- A Bittersweet Response to Infection in Diabetes; Targeting Neutrophils to Modify Inflammation and Improve Host Immunity. Frontiers in Immunology, 12.
- Blood Glucose Monitoring by Insulin‐Treated Pilots of Commercial and Private Aircraft: An Analysis of Out‐of‐Range Values. Diabetes, Obesity and Metabolism.
- The impact of hypoglycaemia on the quality of life of family members of adults with type 1 or type 2 diabetes – a qualitative systematic review. Diabetic Medicine.
- Unmet support needs relating to hypoglycaemia among adults with type 1 diabetes: Results of a multi‐country web‐based qualitative study. Diabetic Medicine.
Chapters
- Hypoglycaemia in Diabetes (pp. 579-601). Wiley
- Chapter 49 Hypoglycemia, insulin resistance, and cardiovascular disease: A possible link, Metabolic Syndrome (pp. 597-608). Elsevier
- Hypoglycemia, insulin resistance, and cardiovascular disease: A possible link, Metabolic Syndrome (pp. 597-608). Elsevier
- Hypoglycaemia in Diabetes, Endocrinology and Diabetes (pp. 375-386). Springer International Publishing
- Hypoglycaemia in Diabetes, Endocrinology and Diabetes (pp. 429-443). Springer New York
- Preface In Frier B, Heller S & McCrimmon R (Ed.), Hypoglycaemia in Clinical Diabetes, (pp. x-xi). Wiley
- Pathophysiology of the effects of hypoglycemia on the cardiovascular system (pp. 3-8).
- Does diabetic control matter? (pp. 553-563).
- The Neurosciences and the Practice of Aviation Medicine CRC Press
- Clinical management of type 1 diabetes, Advanced Nutrition and Dietetics in Diabetes (pp. 60-66). John Wiley & Sons, Ltd
- Mortality, Cardiovascular Morbidity and Possible Effects of Hypoglycaemia on Diabetic Complications, Hypoglycaemia in Clinical Diabetes (pp. 263-284). John Wiley & Sons, Ltd
- Nocturnal Hypoglycaemia, Hypoglycaemia in Clinical Diabetes (pp. 96-113). John Wiley & Sons, Ltd
- How Should Hypoglycaemia Unawareness be Managed?, Difficult Diabetes (pp. 168-187). Blackwell Science Ltd
- Mortality, Cardiovascular Morbidity and Possible Effects of Hypoglycaemia on Diabetic Complications, Hypoglycaemia in Clinical Diabetes (pp. 265-283). John Wiley & Sons, Ltd
- Nocturnal Hypoglycaemia, Hypoglycaemia in Clinical Diabetes (pp. 83-99). John Wiley & Sons, Ltd
Conference proceedings papers
- 233-OR: Impact of Nocturnal Hypoglycemia on Daily Sleep Quality, Mood, and Alertness among Adults with Type 1 Diabetes: The Hypo-METRICS (Hypoglycaemia Measurement, Thresholds, and Impacts) Study. Diabetes, Vol. 71(Supplement_1)
- PDB65 PRETRIAL MODELLING METHODS TO JUSTIFY AND INFORM THE DESIGN OF LARGE RCTS - EXPECTED VALUE OF SAMPLE INFORMATION FOR THE DAFNEPLUS DIABETES EDUCATION CLUSTER RCT. Value in Health, Vol. 22 (pp S584-S584)
- Reduced risk of hypoglycaemia and lower HbA(1c) with degludec compared to glargine U300 in insulin-treated patients with type 2 diabetes. DIABETOLOGIA, Vol. 62 (pp S47-S47)
- Non-severe hypoglycaemia predicts increased risk of subsequent severe events in patients with type 2 diabetes. DIABETOLOGIA, Vol. 62 (pp S418-S418)
- Analysis of patients in the dapagliflozin DEPICT-1 and-2 trials in type 1 diabetes according to HbA(1c) subgroup. DIABETOLOGIA, Vol. 62 (pp S347-S347)
- Can computational modelling explain the dead in bed syndrome?. DIABETOLOGIA, Vol. 62 (pp S46-S46)
- An audit on multidisciplinary team-lead 'Impaired Awareness of Hypoglycaemia' clinic: Outcomes, challenges and experience from Sheffield. DIABETIC MEDICINE, Vol. 36 (pp 79-79)
- Design and implementation of a hypoglycaemia toolkit for use in primary care settings. DIABETIC MEDICINE, Vol. 36 (pp 95-95)
- Asymptomatic Hypoglycemia Is Prevalent and Associated with Cardiac Rhythm Disturbances in Survivors of Critical Illness with Insulin-Treated Type 2 Diabetes. C103. CRITICAL CARE: THE LONG WALK - ELUCIDATING OUTCOMES: DEATH, FUNCTIONAL STATUS AND COGNITION
- 1,5-Anhydroglucitol korreliert bei Patienten mit Typ 1 Diabetes unabhängig vom HbA1c-Responderstatus mit der postprandialen Glucose. „Wissenschaft und klinischer Fortschritt – gemeinsam in die Zukunft“ – www.diabeteskongress.de, 9 May 2018 - 12 May 2018.
- Pharmacological autonomic blockade during experimental hypoglycaemia exacerbates cardiac repolarisation abnormalities. DIABETOLOGIA, Vol. 60 (pp S74-S74)
- Risk of cardiac arrhythmias and electrophysiological responses during spontaneous hyperglycaemia in young people with type 1 diabetes. DIABETOLOGIA, Vol. 60 (pp S534-S534)
- Satisfaction with insulin delivery and glucose monitoring modalities among adults with long-standing Type 1 diabetes and problematic hypoglycaemia: results from the HypoCOMPaSS study. DIABETIC MEDICINE, Vol. 34 (pp 30-30)
- Sustained improvement in diabetes-specific quality of life in adults with long-standing Type 1 diabetes and problematic hypoglycaemia: two year results from the HypoCOMPaSS study. DIABETIC MEDICINE, Vol. 34 (pp 13-13)
- Projected long‐term outcomes in patients with type 1 diabetes treated with fast‐acting insulin aspart vs conventional insulin aspart in the UK setting. Diabetes, Obesity and Metabolism, Vol. 19(12) (pp 1773-1780) View this article in WRRO
- Psychometric properties of a new scale assessing the impact of acute postprandial hyperglycaemia: the aPPHG-Q. QUALITY OF LIFE RESEARCH, Vol. 25 (pp 132-133)
- Comparison of two treatment approaches in older patients with type 2 diabetes (IMPERIUM). DIABETOLOGIA, Vol. 59 (pp S395-S396)
- Effect of once-weekly semaglutide on the counter-regulatory response to hypoglycaemia in subjects with type 2 diabetes. DIABETOLOGIA, Vol. 59 (pp S363-S364)
- Hypoglycaemia is associated with increased risk of cardiovascular events: results from the EXAMINE trial. DIABETOLOGIA, Vol. 59 (pp S44-S44)
- Effects of antecedent hypoglycaemia on gastric and cardiac responses to subsequent hypoglycaemia in health. DIABETOLOGIA, Vol. 59 (pp S405-S405)
- Cardiac autonomic regulation during experimental hypoglycaemia in type 1 diabetes with impaired awareness of hypoglycaemia. DIABETOLOGIA, Vol. 58 (pp S63-S63)
- Major cardiovascular outcomes in the EXAMINE trial according to ACE inhibitor use. DIABETOLOGIA, Vol. 58 (pp S395-S396)
- Hypoglycaemia avoidance training improves glucose variability in Type 1 diabetes (HypoCOMPaSS Study). DIABETIC MEDICINE, Vol. 32 (pp 7-7)
- Nocturnal confirmed hypoglycaemia with insulin degludec vs insulin glargine: rate ratios for different definitions. DIABETIC MEDICINE, Vol. 32 (pp 67-67)
- Associations with hyperglycaemia avoidance among adults with long-standing Type 1 diabetes and impaired awareness of hypoglycaemia: baseline characteristics from the HypoCOMPaSS Study. DIABETIC MEDICINE, Vol. 32 (pp 186-186)
- Effect of sleep on cardiac autonomic tone during nocturnal hypoglycaemia in adults with Type 1 diabetes. DIABETIC MEDICINE, Vol. 32 (pp 21-21)
- Cardiac autonomic regulation during experimental hypoglycaemia in Type 1 diabetes with impaired awareness of hypoglycaemia (IAH). DIABETIC MEDICINE, Vol. 32 (pp 61-61)
- Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes. The Lancet, Vol. 385 (pp S96-S96)
- PERFORMANCE DURING UNSUPERVISED CLOSED LOOP IN CHILDREN AND ADULTS WITH TYPE 1 DIABETES: WHAT MAKES THE DIFFERENCE?. DIABETES TECHNOLOGY & THERAPEUTICS, Vol. 17 (pp A100-A101)
- Accuracy of Continuous Glucose Monitoring (CGM) under free-living conditions during three home closed loop studies. DIABETOLOGIA, Vol. 57 (pp S406-S407)
- Effects of baseline glycaemic HbA1c on CV outcomes and blood glucose control during the EXAMINE trial in patients with type 2 diabetes and recent acute coronary syndrome. DIABETOLOGIA, Vol. 57 (pp S357-S357)
- Factors predictive of overnight closed loop performance during free living in children and adults with type 1 diabetes. DIABETOLOGIA, Vol. 57 (pp S414-S414)
- Severe hypoglycaemia often results in hospital visits and ambulance calls regardless of insulin regimen. DIABETOLOGIA, Vol. 57 (pp S204-S204)
- Cardiac autonomic regulation during acute experimental hypoglycaemia in type 2 diabetes. DIABETOLOGIA, Vol. 57 (pp S260-S261)
- Three to four weeks of overnight closed loop insulin delivery during free living: analysis of randomised crossover studies in adults and adolescents with type 1 diabetes. DIABETOLOGIA, Vol. 57 (pp S89-S89)
- Psychosocial impact of closed loop therapy for adults with Type 1 diabetes: overnight closed loop at home study. DIABETIC MEDICINE, Vol. 31 (pp 151-151)
- Effect of hypoglycaemia on thrombosis and inflammation in patients with type 2 diabetes. The Lancet, Vol. 383 (pp S35-S35)
- PSYCHOSOCIAL IMPACT OF CLOSED LOOP THERAPY - ADULTS WITH TYPE 1 DIABETES: OVERNIGHT CLOSED LOOP AT HOME STUDY. DIABETES TECHNOLOGY & THERAPEUTICS, Vol. 16 (pp A102-A102)
- Positive effects of liraglutide as adjunct to insulin in type 1 diabetes: glycaemic control and safety in a randomised, double blind, placebo controlled crossover trial. DIABETOLOGIA, Vol. 56 (pp S7-S8)
- Treatment with liraglutide as adjunct to insulin in type 1 diabetes; effects on counter regulatory response to hypoglycaemia: a randomised, double blind, crossover trial. DIABETOLOGIA, Vol. 56 (pp S404-S405)
- A cross country qualitative investigation of structured education programmes for adults with type 1 diabetes. DIABETOLOGIA, Vol. 56 (pp S452-S453)
- Experimental hypoglycaemia decreases cardiac vagal function for between 7 to 30 days in patients with type 2 diabetes. DIABETOLOGIA, Vol. 56 (pp S243-S243)
- Hypoglycaemia promotes thrombosis and inflammation for at least one week in patients with type 2 diabetes. DIABETOLOGIA, Vol. 56 (pp S243-S243)
- Do high fasting glucose levels suggest nocturnal hypoglycaemia? The Somogyi effect-more fiction than fact?. Diabetic Medicine, Vol. 30(8) (pp 914-917)
- A higher counter-regulatory hormone response is seen with insulin degludec than insulin glargine in response to induced hypoglycaemia in type 1 diabetes. DIABETOLOGIA, Vol. 54 (pp S261-S261)
- Basal-bolus therapy with insulin degludec improves long-term glycaemic control with less nocturnal hypoglycaemia compared with insulin. DIABETOLOGIA, Vol. 54 (pp S425-S425)
- Impaired awareness of hypoglycemia: Commentary. Diabetic Hypoglycemia, Vol. 3(3) (pp 9)
- Meta-Analysis of Overnight Closed-Loop Randomized Studies in Children and Adults with Type 1 Diabetes: The Cambridge Cohort. Journal of Diabetes Science and Technology, Vol. 5(6) (pp 1352-1362)
- Hypoglycemia and clinical islet transplantation. Diabetic Hypoglycemia, Vol. 3(2) (pp 11-12)
- Nature of association between severe hypoglycaemia and risks of vascular events and death in ADVANCE. DIABETOLOGIA, Vol. 53
- Overnight closed-loop glucose control following consumption of alcohol in adults with type 1 diabetes. DIABETOLOGIA, Vol. 53 (pp S25-S26)
- Targeting acute hyperglycaemia in clinical practice. Diabetes Research and Clinical Practice, Vol. 78(3) (pp S40-S46) View this article in WRRO
- Do high fasting glucose levels suggest nocturnal hypoglycaemia? The Somogyi effect - fact or fiction?. DIABETOLOGIA, Vol. 50 (pp S335-S336)
- Frequency and motives of blood glucose self-monitoring in type I diabetes: association with glycaemic control, complications, and patient characteristics. DIABETOLOGIA, Vol. 49 (pp 494-494)
- Maternal hypoglycaemia and glycaemic control in pregnancy: a randomised trial comparing insulin aspart with human insulin in 322 subjects with type 1 diabetes. DIABETOLOGIA, Vol. 49 (pp 576-577)
- Sensitivity and specificity of CGMS for identifying clinially relevant symptomatic hypoglycaemia. DIABETOLOGIA, Vol. 49 (pp 507-508)
- Improved glycaemic control with insulin glargine plus insulin lispro: a multicentre, randomized, cross-over trial in people with Type 1 diabetes. Diabetic Medicine, Vol. 23(3) (pp 285-292)
- Feature extraction and classification of electrocardiogram (ECG) signals related to hypoglycaemia. Computers in Cardiology, 2003, 24 September 2003 - 24 September 2003.
- Effect of atenolol on QTc interval lengthening during hypoglycaemia in Type 1 diabetes. DIABETOLOGIA, Vol. 45 (pp A78-A78)
- A pharmacokinetic-pharmacodynamic model to explain the biphasic insulinergic effect of tolbutamide and the suppressive role of lowering blood glucose on this effect. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol. 42(5) (pp P675-P676)
- Incorporating psychosocial characteristics in cost-effectiveness modelling of Type 1 diabetes
- Can changes in QT interval be used to predict the onset of hypoglycemia in type 1 diabetes?. Computers in Cardiology 2000. Vol.27 (Cat. 00CH37163)
- QT measurement for TU fused ECG morphology as exhibited during hypoglycaemia. Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)
Reports
- Considerations for assessing the potential effects of antidiabetes drugs on cardiac ventricular repolarization: A report from the Cardiac Safety Research Consortium
- Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society View this article in WRRO
- Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society
- Organizing and delivering diabetes education and self-care support: Findings of scoping project
Posters
- The Cost-Effectiveness of 5-week versus 1-week DAFNE Structured Education in Type 1 Diabetes: A Preliminary Evaluation Using the Sheffield Type 1 Diabetes Policy Model (Diabetes UK Professional Conference 13-15 March 2013).
- The Cost-Effectiveness of Dose Adjustment For Normal Eating (DAFNE) Structured Education in Type 1 Diabetes: An Update using the Sheffield Type 1 Diabetes Policy Model (Diabetes UK Professional Conference 13-15 March 2013).
Other
- Correction to: The suitability of patient-reported outcome measures used to assess the impact of hypoglycaemia on quality of life in people with diabetes: a systematic review using COSMIN methods.. Diabetologia.
- Response to Comment on Novodvorsky et al. Diurnal Differences in Risk of Cardiac Arrhythmias During Spontaneous Hypoglycemia in Young People With Type 1 Diabetes. Diabetes Care 2017;40:655–662. Diabetes Care, 41(4), e65-e66.
- Response to Comment on Little et al. Recovery of Hypoglycemia Awareness in Long-standing Type 1 Diabetes: A Multicenter 2 × 2 Factorial Randomized Controlled Trial Comparing Insulin Pump With Multiple Daily Injections and Continuous With Conventional Glucose Self-monitoring (HypoCOMPaSS). Diabetes Care 2014;37:2114–2122. Diabetes Care, 37(12), e272-e273.
- Lifecourse: management of type 1 diabetes. The Lancet Diabetes & Endocrinology, 2(3), 194-195.
- Self-monitoring of blood glucose: a promise still unfulfilled?. Diabetologia, 57(5), 847-849.
- How to reduce the risk of failing to reach recruitment targets: lessons learnt from a pump pilot trial. Diabetic Medicine, 29(12), 1600-1601.
- Diversity in diabetes: the role of insulin aspart. Diabetes/Metabolism Research and Reviews, 28(1), 50-61.
- Hypoglycaemia unawareness. Practical Diabetes International, 28(5), 227-232.
- Hypoglycaemia: Its pathophysiology in insulin treated diabetes and hypoglycaemia unawareness. The British Journal of Diabetes & Vascular Disease, 11(1_suppl), 6-9.
- Hypoglycaemia in diabetes. Medicine, 38(12), 671-675.
- Self-destructive behavior - A case of recurrent severe hypoglycemia. Diabetic Hypoglycemia, 2(3), 17-18.
Preprints
- The collaborative working group method for pre-trial knowledge mobilisation: a qualitative evaluation of a structured process for iteratively refining a complex intervention (DAFNEplus), Research Square Platform LLC.
- One year health outcomes associated with systemic corticosteroids for COVID-19: a longitudinal cohort study, Cold Spring Harbor Laboratory.
- Cohort Profile: Post-hospitalisation COVID-19 study (PHOSP-COVID), Cold Spring Harbor Laboratory.
- Physical, cognitive and mental health impacts of COVID-19 following hospitalisation – a multi-centre prospective cohort study, Cold Spring Harbor Laboratory.
- Grants
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National Institute of Health Research, Programme Grant October 2007-April 2013. Improving management of Type 1 diabetes in the UK: the DAFNE programme as a research test-bed. Principal
Investigator in collaboration with Dr J Lawton, Dr M Clarke, Ms G Thompson, Prof S Amiel, Prof M Campbell, Dr P Mansell, Dr I Lawrence, Ms C Taylor, Ms L Oliver (Chief Investigator) £1.8m
Diabetes UK. Jan 2009-July 2013. KICk-OFF: A multi-centre, randomised controlled trial comparing intensive structured education with standard education in 11-16 year olds on intensive insulin therapy.
Dr K Price, Prof C Eiser Dr J Wales, Dr J Freeman (co-investigator) £1.35m
Diabetes UK. April 2008-March 2011. Overnight hypoglycaemia prevention in adult subjects with type 1 diabetes: Closing the loop
Dr R Hovorka, Prof S Amiel Dr M Evans, (co-investigator) £750k
Diabetes UK. Sep 2009-March 2012. Prevention of recurrent severe hypoglycaemia: a definitive RCT comparing optimised MDI and CSII with or without adjunctive real-time continuous glucose monitoring
Dr J Shaw, Prof D Kerr, Dr D Flanagan, Dr M Evans, Dr J Speight (co-investigator) £1.4m
South Yorkshire Research Collaborations for Leadership in Applied Health Research and Care October 2008- September 2013 Diabetes Theme Adolescent Project to develop a structured training programme and other interventions to improve outcomes in young people with Type 1 diabetes aged 16-21years.
Prof C Eiser, Dr A Scott, (Chief Investigator) £900k
Health Technology Assessment Grant. June 2011-Dec 2015 The REPOSE (Relative Effectiveness of Pumps Or Structured Education) Trial.
Prof N Waugh, Dr C Cooper, Prof M Campbell, Prof S Amiel, Dr P Hammond, Ms C Taylor, Dr R Lindsay, Dr J Lawton, Dr K Barnard, Dr M Evans, Dr F Green, Dr A Jaap, Ms C Taylor, Prof S Dixon, (Chief Investigator). £2.0m
Health Technology Assessment Grant. 14/213/10 January 2016 – June 2017 A systematic review of psychological interventions to improve motivation for self-management in people with type 1 and type 2 diabetes
Dr K Winkley, Prof Khalida Ismail, Prof A Brennan (co-investigator) £176.74k
National Institute of Health Research, Programme Grant March 2016- September 2021. Developing and trialling the DAFNEplus (Dose for Adjustment for Normal Eating) intervention. A lifelong approach to promote effective self-management in adults with type 1 diabetes.
Chief Investigator in collaboration with Professor J Lawton, Professor S Michie, Ms G Thompson, Prof S Amiel, Prof M Campbell, Dr P Mansell, Dr D Hopkins, Ms C Taylor, Dr J Elliott, Mr S Fisher, Prof L Yardley, Prof A Brennan, Dr J Cohen, Dr D Cooke, Prof W Baird. (Chief Investigator) £2.75m
- Professional activities and memberships
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Activities and Distinctions
- Diabetes UK Research Committee 2005 – 2015. Professional Advisory Council 2003-2008. Scientific and Research Advisory Group. 2009- present, Arnold Bloom Lecture, Diabetes UK, 2012
- Member of NICE/RCP working groups developing national guidelines for the management of adult Type 1 (2002) and Type 2 diabetes (2000).
- Deputy Chair Joint DoH/MRC Research Advisory Committee on Diabetes 2002
- Member of MRC College of Experts 2005-2009
- Acting Portfolio Director in Diabetes, Dept of Health, Sept – Dec 2004
- I chaired the Clinical Studies Advisory Group (2008-2014) and sit on the Management Committee of the UK Diabetes Clinical Research Network. I am currently the acting National Speciality Lead for Diabetes in the NIHR Clinical Research Network.
- NIHR Senior Investigator (since 2012)
- Regional Diabetes Specialty Lead, Yorks/Humber CRN, 2014 to present
- National Diabetes Speciality Lead, NIHR CRN, 2015 to present