Professor Nick Bishop

Clinical Medicine, School of Medicine and Population Health

Chair in Paediatric Bone Disease

Nick Bishop Staff profile
Profile picture of Nick Bishop Staff profile
n.j.bishop@sheffield.ac.uk

Full contact details

Professor Nick Bishop
Clinical Medicine, School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX
Profile

For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk

The UK's only Professor of Paediatric Bone Disease.

Trained in Manchester (clinical), Cambridge (MRC and Wellcome Fellowships) and Montreal (visiting Professor at McGill). Appointed to Chair in Sheffield in 1998.

Clinical research group focuses on the treatment of childhood bone fragility and rare bone diseases; basic science group on early life events and skeletal development, as well as the pathophysiology of childhood bone diseases.

Research interests

Our research aims to improve outcomes for children with inherited and acquired bone diseases and understand better the factors contributing to fracture in apparently healthy children.

We are working with colleagues locally and nationally to determine the phenotype-genotype relationships in early onset bone fragility disorders, and to develop a pipeline to bring forward new therapies in these disorders.

Our previous clinical studies of the use of bisphosphonates in osteogenesis imperfecta (OI) showed that bone mass increases in a dose-responsive manner in moderate-severely affected children without a clear reduction in fracture risk; and that mildly affected children can reduce fracture risk by approximately 50% when taking the oral bisphosphonate risedronate. We recruited the first UK patient to the Amgen-funded study of Denosumab in OI. We participated in the global studies of asfotase alfa, a recombinant enzyme replacement therapy for hypophosphatasia (HPP), leading in Europe initially with children travelling from other EU countries to participate.

We have developed a new biomarker to assess the acute skeletal response to mechanical stimulation that is now being used in prospective studies of children with fracture and OI.

In collaboration with colleagues nationally, we are assessing the effects of antenatal vitamin D supplementation on skeletal development and health; we have developed a model system of antenatal vitamin D depletion in which we are assessing the postnatal response to mechanical loading.

Internationally, we are developing the European Reference Network for Rare Bone Diseases that will deliver improved health care outcomes for patients with skeletal disorders such as OI and HPP, translating our research into clinical practice.


Principal funding sources:

  • MRC
  • NIHR
  • Arthritis Research Campaign
  • Sir Halley Stewart Trust
  • Amgen
  • Alexion Pharma
Publications

Show: Featured publications All publications

Journal articles

All publications

Journal articles

Chapters

  • Bishop N (2019) Osteogenesis Imperfecta, Encyclopedia of Endocrine Diseases (pp. 355-365). Elsevier RIS download Bibtex download
  • Bishop N (2015) Case 112, Diagnosis of Non-Accidental Injury: Illustrated Clinical Cases (pp. 255-256). RIS download Bibtex download
  • Bishop N (2015) Case 114, Diagnosis of Non-Accidental Injury: Illustrated Clinical Cases (pp. 259-260). RIS download Bibtex download
  • Bishop N (2015) Case 70, Diagnosis of Non-Accidental Injury: Illustrated Clinical Cases (pp. 159-160). RIS download Bibtex download
  • Bishop N (2015) Case 10, Diagnosis of Non-Accidental Injury: Illustrated Clinical Cases (pp. 19-22). RIS download Bibtex download
  • Bishop NJ & Russell G (2014) Bisphosphonates, Osteogenesis Imperfecta (pp. 495-500). Elsevier RIS download Bibtex download
  • Bishop NJ & Russell G (2013) Bisphosphonates, Osteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease (pp. 495-500). RIS download Bibtex download
  • Aiton N, Archer N, Ayling RM, Balchin I, Barth PG, Bedford Russell A, Bishop N, Blott M, Bowron A, Boylan G , Cairns P et al (2012) Contributors, Rennie & Roberton's Textbook of Neonatology (pp. ix-xv). Elsevier RIS download Bibtex download
  • Adams JE, Bachrach LK, Bastepe M, Bergwitz C, Bianchi ML, Bianco P, Bishop N, Bonewald LF, Bonjour J-P, Cameron N , Carpenter TO et al (2012) List of Contributors, Pediatric Bone (pp. xi-xiii). Elsevier RIS download Bibtex download
  • Bishop N, Fewtrell M & Harvey NC (2011) Metabolic Bone Disease in the Neonatal Period and its Later Sequelae, Pediatric Bone: Biology and Diseases (pp. 655-677). RIS download Bibtex download
  • Arundel P & Bishop NJ (2010) Osteogenesis Imperfecta, Bone and Development (pp. 215-231). Springer London RIS download Bibtex download
  • BISHOP NJ (2005) Perinatal Vitamin D Actions, Vitamin D (pp. 803-810). Elsevier RIS download Bibtex download
  • Bishop N & Fewtrell M (2003) Metabolic Bone Disease of Prematurity, Pediatric Bone: Biology & Diseases (pp. 567-581). RIS download Bibtex download
  • Palusci VJ, Nazer D & Brennan PO () Diagnosis of Non-accidental Injury CRC Press RIS download Bibtex download
  • Blake G, E. Adams J & Bishop N () DXA in Adults and Children, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism (pp. 249-263). John Wiley & Sons, Inc. RIS download Bibtex download
  • Bishop N & Glorieux FH () Juvenile Osteoporosis, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism (pp. 468-472). John Wiley & Sons, Inc. RIS download Bibtex download
  • Bishop NJ, Sawyer AJ & Leonard MB () Looking to the Future of Pediatric Bone Densitometry, Bone Densitometry in Growing Patients (pp. 173-178). Humana Press RIS download Bibtex download

Conference proceedings papers

  • Bishop N, Rush E, Sutton VR, Sangiorgi L, Semler O, Gottesman G, Mistry A, MacKinnon A, Woo C, Wang H , Putnam W et al (2023) Orbit: A Randomized, Double-Blind, Placebo-controlled, Phase 2/3 Study to Assess the Efficacy and Safety of Setrusumab in Pediatric and Young Adult Participants with Osteogenesis Imperfecta. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 38 (pp 325-325) RIS download Bibtex download
  • Bishop N, Rush E, Sutton VR, Sangiorgi L, Semler O, Gottesman G, Cassinelli H, Mistry A, MacKinnon A, Wang H , Putnam W et al (2023) Orbit: A Randomized Phase 2/3 Study Consisting of a Phase 2 Single-Blind, Dose-Evaluation Phase and a Phase 3, Double-Blind, Placebo-controlled Phase to Assess the Efficacy and Safety of Setrusumab in Subjects with Osteogenesis Imperfecta. HORMONE RESEARCH IN PAEDIATRICS, Vol. 96(SUPPL 2) (pp 67-68) RIS download Bibtex download
  • Curtis EM, Moon RJ, D'Angelo S, Crozier SR, Bishop NJ, Gopal-Kothandapani S, Kennedy S, Papageorghiou AT, Fraser R, Gandhi SV , Schoenmakers I et al (2020) VITAMIN D SUPPLEMENTATION IN PREGNANCY RESULTS IN GREATER OFFSPRING BONE MASS AT 4 YEARS: FINDINGS FROM THE MAVIDOS TRIAL. OSTEOPOROSIS INTERNATIONAL, Vol. 31(SUPPL 1) (pp S50-S50) RIS download Bibtex download
  • Curtis EM, Moon RJ, D'Angelo S, Crozier SR, Bishop NJ, Gopal-Kothandapani S, Kennedy S, Papageorghiou AT, Fraser R, Gandhi SV , Schoenmakers I et al (2020) PREGNANCY VITAMIN D SUPPLEMENTATION LEADS TO GREATER OFFSPRING BONE MINERAL DENSITY AT 4 YEARS: THE MAVIDOS RANDOMISED PLACEBO CONTROLLED TRIAL. RHEUMATOLOGY, Vol. 59 RIS download Bibtex download
  • Alshamrani HA, Paggiosi MA, Rigby AS, Bishop NJ & Offiah AC (2020) EFFECT OF HIGH DOSE VITAMIN D AND WHOLE BODY VIBRATION ON BONE DENSITY OF THE DISTAL TIBIA AS MEASURED BY HR-PQCT, SERUM 25(OH)D AND PTH. OSTEOPOROSIS INTERNATIONAL, Vol. 31(SUPPL 1) (pp S443-S444) RIS download Bibtex download
  • Peacock A, Offiah AC, Balasubramanian M, Bishop N & Arundel P (2019) Radiographic evidence of zoledronic acid given during pregnancy - a case report. Bone Abstracts, Vol. 7. Salzburg, Austria, 22 June 2019 - 25 June 2019. View this article in WRRO RIS download Bibtex download
  • Curtis EM, Parsons C, Maslin K, D'Angelo S, Moon RJ, Crozier SR, Gossiel F, Bishop NJ, Kennedy S, Papageorghiou AT , Fraser R et al (2019) BONE TURNOVER IN PREGNANCY, MEASURED BY URINARY C-TERMINAL TELOPEPTIDE OF TYPE I COLLAGEN (CTX), IS INFLUENCED BY VITAMIN D SUPPLEMENTATION AND IS ASSOCIATED WITH MATERNAL BONE HEALTH: FINDINGS FROM THE MAVIDOS TRIAL. RHEUMATOLOGY, Vol. 58 RIS download Bibtex download
  • Curtis E, Moon R, D'Angelo S, Crozier S, Inskip H, Godfrey K, Cooper C, Harvey N, Bishop N, Gopal S , Kennedy S et al (2019) Maternal pregnancy vitamin D supplementation is associated with greater offspring bone mineral density at 4 years: findings from the MAVIDOS trial. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 34 (pp 68-68) RIS download Bibtex download
  • Curtis E, Krstic N, Cook E, D'Angelo S, Crozier SR, Moon RJ, Murray R, Garratt E, Costello P, Bishop N , Kennedy S et al (2018) VITAMIN D SUPPLEMENTATION IN PREGNANCY LEADS TO ALTERED PERINATAL RXRA DNA METHYLATION: FINDINGS FROM THE MAVIDOS TRIAL. OSTEOPOROSIS INTERNATIONAL, Vol. 29 (pp 628-628) RIS download Bibtex download
  • Curtis E, Parsons C, Maslin K, D'Angelo S, Moon R, Crozier S, Gossiel F, Bishop N, Kennedy S, Papageorghiou A , Fraser R et al (2018) URINE C-TERMINAL TELOPEPTIDE OF TYPE I COLLAGEN (CTX) IN PREGNANCY IS INFLUENCED BY VITAMIN D SUPPLEMENTATION AND IS ASSOCIATED WITH MATERNAL BONE HEALTH: FINDINGS FROM THE MAVIDOS TRIAL. OSTEOPOROSIS INTERNATIONAL, Vol. 29 (pp 606-606) RIS download Bibtex download
  • Curtis E, Parsons C, Maslin K, D'Angelo S, Moon R, Crozier S, Gossiel F, Bishop N, Kennedy S, Papageorghiou A , Fraser R et al (2018) Natural history of maternal urinary beta-C-terminal telopeptide of type I collagen (CTX) in pregnancy, and response to cholecalciferol supplementation: findings from the MAVIDOS trial. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 33 (pp 109-109) RIS download Bibtex download
  • Schoenmakers I, Jones K, Assar S, D'Angelo S, Prentice A, Bishop N, Kennedy S, Papageorghiou A, Fraser R, Gandhi S , Curtis E et al (2018) Dynamics of Vitamin D Metabolism in the Maternal-Fetal Dyad in Response to Vitamin D Supplementation. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 33 (pp 356-356) RIS download Bibtex download
  • Curtis EM, Maslin K, D'Angelo S, Moon RJ, Crozier SR, Gossiel F, Bishop NJ, Kennedy S, Papageorghiou AT, Fraser R , Gandhi SV et al (2018) PLASMA CTX IN PREGNANCY IS ALTERED BY CHOLECALCIFEROL SUPPLEMENTATION AND IS ASSOCIATED WITH MATERNAL BONE INDICES: THE MAVIDOS TRIAL. OSTEOPOROSIS INTERNATIONAL, Vol. 29 (pp S70-S71) RIS download Bibtex download
  • Bishop N (2018) OSTEOGENESIS IMPERFECTA: PATHOPHYSIOLOGY AND TREATMENT IN CHILDHOOD. RHEUMATOLOGY, Vol. 57 RIS download Bibtex download
  • Bishop N (2018) Hypophosphatasia: Disease and Treatment. HORMONE RESEARCH IN PAEDIATRICS, Vol. 90 (pp 9-9) RIS download Bibtex download
  • Moon R, Harvey N, Cooper C, D'Angelo S, Curtis E, Crozier S, Barton S, Robinson S, Godfrey K, Graham N , Holloway J et al (2017) The response to antenatal cholecalciferol supplementation is associated with common vitamin D related genetic variants: findings from the MAVIDOS trial.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 32 (pp S208-S208) RIS download Bibtex download
  • Curtis E, Krstic N, Cook E, D'Angelo S, Crozier S, Moon R, Murray R, Garratt E, Costello P, Bishop N , Kennedy S et al (2017) Maternal gestational vitamin D supplementation alters perinatal RXRA DNA methylation: findings from the MAVIDOS trial.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 32 (pp S61-S61) RIS download Bibtex download
  • Hogler W, Bishop N, Arundel P, Scott J, Mughal Z, Padidela R, Nightingale P, Shaw N & Crabtree N (2017) The effect of whole body vibration training on bone and muscle function in children with osteogenesis imperfecta and limited mobility: a randomized controlled pilot trial. Bone Abstracts, Vol. 6, 10 June 2017 - 13 June 2017. View this article in WRRO RIS download Bibtex download
  • Balasubramanian M, Hurst J, DeVile C, Bishop N, Arundel P, Offiah A, Pollitt R, Hughes D, Longman D, Caceres J & Skerry T (2017) NBAS variants causing a novel form of inherited bone fragility. Bone Abstracts, Vol. 6(2017). Bristol, UK, 10 June 2017 - 13 June 2017. View this article in WRRO RIS download Bibtex download
  • Curtis E, Cook E, Krstic N, D'Angelo S, Crozier S, Moon R, Murray R, Garratt E, Costello P, Bishop NJ , Kennedy S et al (2017) DNA METHYLATION AT THE RXRA PROMOTER AT BIRTH IS ASSOCIATED WITH GESTATIONAL VITAMIN D SUPPLEMENTATION: RESULTS FROM THE MAVIDOS TRIAL. OSTEOPOROSIS INTERNATIONAL, Vol. 28 (pp S72-S73) RIS download Bibtex download
  • Moon RJ, Harvey NC, Cooper C, D'Angelo S, Curtis EM, Crozier SR, Robinson SM, Graham NJ, Holloway JW, Bishop NJ , Kennedy S et al (2017) 25-HYDROXYVITAMIN D RESPONSE TO GESTATIONAL CHOLECALCIFEROL SUPPLEMENTATION IS ASSOCIATED WITH COMMON VITAMIN D RELATED GENETIC VARIANTS: FINDINGS FROM THE MAVIDOS TRIAL. OSTEOPOROSIS INTERNATIONAL, Vol. 28 (pp S70-S71) RIS download Bibtex download
  • Lewis LB, Alison L & Bishop N (2017) G70(P) Biochemical bone profiling in children with fractures suspicious of non-accidental injury (NAI). Archives of Disease in Childhood, Vol. 102(Suppl 1) (pp a29-a29), 24 May 2017 - 26 May 2017. View this article in WRRO RIS download Bibtex download
  • Moon RJ, Harvey NC, Cooper C, D'Angelo S, Curtis EM, Crozier SR, Robinson SM, Graham NJ, Holloway JW, Bishop NJ , Kennedy S et al (2017) 25-HYDROXYVITAMIN D RESPONSE TO GESTATIONAL CHOLECALCIFEROL SUPPLEMENTATION IS ASSOCIATED WITH COMMON VITAMIN D RELATED GENETIC VARIANTS: FINDINGS FROM THE MAVIDOS TRIAL. RHEUMATOLOGY, Vol. 56 (pp 153-153) RIS download Bibtex download
  • Cook E, Curtis EM, Krstic N, D'Angelo S, Crozier SR, Moon RJ, Murray R, Garratt E, Costello P, Bishop NJ , Kennedy S et al (2017) PERINATAL DNA METHYLATION AT THE RXRA PROMOTER IS ASSOCIATED WITH GESTATIONAL VITAMIN D SUPPLEMENTATION: RESULTS FROM THE MAVIDOS TRIAL. RHEUMATOLOGY, Vol. 56 (pp 112-112) RIS download Bibtex download
  • Hogler W, Scott J, Bishop NJ, Arundel P, Nightingale P, Mughal Z, Padidela R, Shaw NJ & Crabtree N (2017) THE EFFECT OF WHOLE BODY VIBRATION TRAINING ON BONE AND MUSCLE FUNCTION IN CHILDREN WITH OSTEOGENESIS IMPERFECTA. HORMONE RESEARCH IN PAEDIATRICS, Vol. 88 (pp 444-444) RIS download Bibtex download
  • Harvey N, Moon R, D'Angelo S, Crozier S, Inskip H, Schoenmakers I, Bishop N, Kennedy S, Papageorghiou A, Fraser R , Gandhi S et al (2016) PREDICTORS OF MATERNAL 25(OH)-VITAMIN D RESPONSE TO ANTENATAL VITAMIN D SUPPLEMENTATION: RESULTS FROM THE MAVIDOS TRIAL. OSTEOPOROSIS INTERNATIONAL, Vol. 27 (pp 628-629) RIS download Bibtex download
  • Harvey NC, Moon RJ, D'Angelo S, Crozier S, Schoenmakers I, Bishop NJ, Kennedy S, Papageorghiou AT, Fraser R, Gandhi SV , Prentice A et al (2016) DETERMINANTS OF THE MATERNAL RESPONSE TO VITAMIN D SUPPLEMENTATION DURING PREGNANCY: THE MAVIDOS TRIAL. OSTEOPOROSIS INTERNATIONAL, Vol. 27 (pp S49-S50) RIS download Bibtex download
  • Harvey NC, Bishop NJ, Kennedy S, Papageorghiou AT, Schoenmakers I, Fraser R, Gandhi SV, Carr A, D'Angelo S, Crozier SR , Moon RJ et al (2016) MATERNAL GESTATIONAL VITAMIN D SUPPLEMENTATION RESULTS IN GREATER BONE MASS FOR OFFSPRING BORN DURING WINTER MONTHS: THE MAVIDOS MULTICENTRE RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL. RHEUMATOLOGY, Vol. 55 (pp 41-41) RIS download Bibtex download
  • Cooper C, Harvey NC, Javaid MK, Bishop NJ, Kennedy S, Papageorghiou AT, Fraser R, Gandhi SV, D'angelo S, Crozier SR , Moon RJ et al (2015) EFFECTIVENESS OF MATERNAL VITAMIN D SUPPLEMENTATION: A MULTICENTRE RANDOMISED, DOUBLE-BLIND, PLACEBO CONTROLLED TRIAL (MAVIDOS). OSTEOPOROSIS INTERNATIONAL, Vol. 26 (pp S40-S40) RIS download Bibtex download
  • Razaghi H, Saatchi R, Huggins T, Bishop N, Burke D & Offiah AC (2014) Correlation analysis of bone vibration frequency and bone mineral density in children. 2014 9th International Symposium on Communication Systems, Networks & Digital Sign (CSNDSP), 23 July 2014 - 25 July 2014. RIS download Bibtex download
  • Arshad F, Hinton S, Bishop N & Arundel P (2014) G67(P) Variation in response to vitamin D therapy in a series of children referred to a paediatric bone disease service. Archives of Disease in Childhood, Vol. 99(Suppl 1) (pp A29-A29) RIS download Bibtex download
  • Whyte M, Simmons JH, Lutz RE, Moseley S, Melian A, Odrljin T & Bishop N (2014) Enzyme-Replacement Therapy in Life-Threatening Hypophosphatasia: The 3-Year Experience with Asfotase Alfa.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 29 (pp S120-S120) RIS download Bibtex download
  • Harvey N, Holroyd C, Ntani G, Javaid K, Cooper P, Moon R, Cole Z, Tinati T, Bishop N, Godfrey K , Dennison E et al (2013) MATERNAL VITAMIN D STATUS IN PREGNANCY AND OFFSPRING BONE HEALTH: A SYSTEMATIC REVIEW AND META-ANALYSIS. OSTEOPOROSIS INTERNATIONAL, Vol. 24 (pp S33-S33) RIS download Bibtex download
  • Harvey N, Holroyd C, Ntani G, Javaid K, Cooper P, Moon R, Cole Z, Tinati T, Bishop N, Godfrey K , Dennison E et al (2013) Maternal Pregnancy Vitamin D Status and Offspring Bone Health: A Systematic Review and Meta-analysis. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 28 RIS download Bibtex download
  • Forestier-Zhang L, Grabowski PS, Gallagher O, Patel A, Madan S, Arundel P & Bishop N (2013) Assessing bone quality and fracture resistance in children using microindentation. Bone Abstracts, Vol. 2 (pp P86-P86) RIS download Bibtex download
  • Foster S, Grabowski PS, Gallagher O, Besio R, Rossi A, Bishop N & Forlino A (2013) Prolidase deficient mice are osteoporotic in early life. Bone Abstracts, Vol. 2 (pp OC22-OC22) RIS download Bibtex download
  • Forbes M, Bishop N & Grabowski PS (2013) Reference point indentation testing detects age-related changes in tissue mechanical properties in mice. Bone Abstracts, Vol. 2 (pp P81-P81) RIS download Bibtex download
  • Fewtrell MS, Edmonds CJ, Isaacs E, Bishop NJ & Lucas A (2011) Aluminium exposure from parenteral nutrition in preterm infants and later health outcomes during childhood and adolescence. PROCEEDINGS OF THE NUTRITION SOCIETY, Vol. 70(3) (pp 299-304) RIS download Bibtex download
  • Bishop N (2011) Determinants and associations of fracture in children. BONE, Vol. 48 (pp S58-S58) RIS download Bibtex download
  • Bishop N, Greenberg C, Craig S, McGinn M, Simmons J, Russell W, Bauer M, Taylor J, Salman N, Hamdan M , Bober M et al (2011) Life-threatening hypophosphatasia (HPP): Results of up to two years bone-targeted Enzyme Replacement Therapy (ERT) in infants and young children. BONE, Vol. 48 (pp S82-S82) RIS download Bibtex download
  • Harrison RC, Ward K, Horne C & Bishop NJ (2011) Acute bone response to whole body vibration in pre-pubertal boys. BONE, Vol. 48 (pp S270-S270) RIS download Bibtex download
  • Dimitri P, Wales JK & Bishop N (2009) Osteoprotegerin may be a key determinant of low total body and regional bone mass in obese children. BONE, Vol. 45 (pp S71-S71) RIS download Bibtex download
  • Fewtrell MS, Bishop NJ, Edmonds CJ, Isaacs EB & Lucas A (2009) Aluminium exposure from intravenous feeding solutions and later bone health: 15 year follow-up of a randomised trial in preterm infants. BONE, Vol. 45 (pp S97-S98) RIS download Bibtex download
  • Arundel P, Blades Z, Carlino W, Dimitri PJ, Harrison R, Crook J & Bishop NJ (2009) Relationship between COL1A1 Sp1 and COL1A2 PvuII SNPs and fractures in childhood. BONE, Vol. 45 (pp S53-S53) RIS download Bibtex download
  • Bishop N (2009) OSTEOPOROSIS IN CHILDREN. OSTEOPOROSIS INTERNATIONAL, Vol. 20 (pp S257-S257) RIS download Bibtex download
  • Gossiel F, Hannon RA, Bishop NJ, Dimitri P & Eastell R (2008) The Relationship of Urinary Excretion of C-Telopeptides to Growth in Children. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 23 (pp S110-S110) RIS download Bibtex download
  • Dimitri PJ, Arundel P, Wales JKW & Bishop NJ (2008) Fat children, thin bones. BONE, Vol. 42 (pp S48-S49) RIS download Bibtex download
  • Bishop NJ (2008) Therapy of paediatric bone conditions. BONE, Vol. 42 (pp S68-S68) RIS download Bibtex download
  • Briggs T, Abdel-Salam GMH, Baxter P, Bishop N, Chityat D, Chong WK, Hughes I, Nischall KK, Rice GI, Stephenson JBP , Surtees R et al (2007) Cerebroretinal microangiopathy with calcification and cysts (CRMCC). JOURNAL OF MEDICAL GENETICS, Vol. 44 (pp S49-S49) RIS download Bibtex download
  • Scott DI, Coxon FP, Sobacchi C, Frattini A, Pangrazio A, Guerrini M, Susani L, Teti A, Messina C, Errigo G , Abinun M et al (2007) RANKL mutations are responsible for the defective osteoclast formation seen in six patients with osteoclast-poor osteopetrosis. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 22(7) (pp 1111-1112) RIS download Bibtex download
  • Bishop N (2007) Steroid-induced osteoporosis in children. BONE, Vol. 40(6) (pp S9-S9) RIS download Bibtex download
  • Dimitri P, Crook J & Bishop N (2007) Changes in body composition following 3 years of pamidronate therapy in osteogenesis imperfecta. BONE, Vol. 40(6) (pp S39-S40) RIS download Bibtex download
  • Patel A, Pollitt R, Dalton A, Saarinen A & Bishop NJ (2007) Children with recurrent fractures and low bone mass or idiopathic juvenile osteoporosis may have abnormalities in the canonical Wnt-signalling pathway through LRP5. BONE, Vol. 40(6) (pp S71-S72) RIS download Bibtex download
  • Blades HZ, Carlino W, Durkie M, Dalton A & Bishop NJ (2007) Genetic polymorphisms and fracture risk in children. BONE, Vol. 40(6) (pp S28-S29) RIS download Bibtex download
  • Carlino W, Hangartner TN, Blades HZ, Vickers Y & Bishop NJ (2007) Bone mass and architecture in children with and without fractures. BONE, Vol. 40(6) (pp S32-S33) RIS download Bibtex download
  • Sobacchi C, Coxon F, Frattini A, Scott D, Pangrazio A, Guerrini M, Susani L, Teti A, Messina C, Errigo G , Abinun M et al (2007) Identification of novel mutations in rankl as a cause of osteoclast-poor osteopetrosis. CALCIFIED TISSUE INT, Vol. 80 (pp S35-S35) RIS download Bibtex download
  • Still K, Grabowski P, Perry M & Bishop NJ (2006) The peroxisome proliferator activator receptor Alpha/Delta (PPARa/d) agonists linoleic acid and bezafibrate upregulate osteoblast differentiation and induce periosteal bone formation in vivo.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 21 (pp S204-S204) RIS download Bibtex download
  • Clark EM, Ness AR, Bishop NJ & Tobias JH (2006) The association between bone mass and fractures in childhood: A prospective cohort study.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 21 (pp S19-S19) RIS download Bibtex download
  • Clark EM, Ness AR, Bishop NJ & Tobias JH (2006) Skeletal fragility is an important determinant of fracture risk in children, even in the presence of significant trauma.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 21 (pp S30-S30) RIS download Bibtex download
  • Still K, Perry MJ, Grabowski P & Bishop NJ (2006) Activation of peroxisome proliferator activated receptor delta (PPARdelta) increases periosteal bone formation. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 21(7) (pp 1152-1152) RIS download Bibtex download
  • Pollitt R, McMahon R, Nunn J, Bamford R, Afifi A, Bishop N & Dalton A (2005) Mutation analysis of COL1A1 and COL1A2 in a cohort of patients with osteogenesis imperfecta type I-IV. JOURNAL OF MEDICAL GENETICS, Vol. 42 (pp S91-S91) RIS download Bibtex download
  • Thompson GA, Burgio DE, Russell DA, Sun LA & Bishop N (2005) Risedronate pharmacokinetics in children with osteogenesis imperfecta. BONE, Vol. 36 (pp S223-S224) RIS download Bibtex download
  • Grabowski PS, Shaw NJ, Darbyshire PJ, Hughes D & Bishop NJ (2005) Failure of a successful bone marrow transplant to rescue osteoclast deficient autosomal recessive osteopetrosis. BONE, Vol. 36 (pp S226-S226) RIS download Bibtex download
  • Conroy KA, Hill C, Bishop N, Knowles L, Ford D, Scott D & Walker E (2005) Development of a specific assessment tool for children with osteogenesis imperfecta. BONE, Vol. 36 (pp S51-S51) RIS download Bibtex download
  • Thompson GA, Burgio DE, Bishop N, Russell DA & Sun LA (2005) Risedronate pharmacokinetics in children with osteogenesis imperfecta. BONE, Vol. 36 (pp S82-S82) RIS download Bibtex download
  • Afifi A, Grabowski P, Olpin S, Bishop N & Dalton A (2005) Chimeraplasty for gene repair in carnitine palmitoyl transferase II deficiency. BONE, Vol. 36 (pp S28-S28) RIS download Bibtex download
  • Manias K & Bishop NJ (2005) Phalangeal ultrasound and fracture risk in childhood. BONE, Vol. 36 (pp S100-S100) RIS download Bibtex download
  • Crabtree NJ, Oldroyd B, Bishop NJ, Shaw NJ, Adams JE, Ward KA, Fewtrell M, Gordon I & Truscott J (2005) A paediatric lumbar spine phantom for inter-site and inter-machine cross-calibration. BONE, Vol. 36 (pp S44-S44) RIS download Bibtex download
  • Senthilnathan S, Walker E, Cousins R, Silverwood B & Bishop NJ (2005) Pamidronate for infants with osteogenesis imperfecta; comparison of different doses. BONE, Vol. 36 (pp S82-S82) RIS download Bibtex download
  • Grabowski PS, Smith S, Jenkins N, Moore H & Bishop NJ (2005) Observations on cell fusion in RAW264.7 cells stimulated with RANK ligand using time lapse videomicroscopy and expression microarrays. BONE, Vol. 36 (pp S25-S26) RIS download Bibtex download
  • Oldroyd B, Milner R, Marsden AJ, Crabtree NJ, Bishop NJ & Truscott JG (2004) Pediatric spine phantom for use in DXA pediatric bone studies. OSTEOPOROSIS INTERNATIONAL, Vol. 15 (pp S21-S21) RIS download Bibtex download
  • Afifi A, McMahon R, Dalton A, Bishop NJ & Grabowski PS (2004) COL3A1: An unsuitable comparator for measuring collagen mRNA expression levels in bone of patients with osteogenesis imperfecta. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 19(6) (pp 1039-1039) RIS download Bibtex download
  • Crow Y, Philippart M, Surtees R, Nischall K, Abdel-Salam G, Baxter P, Bishop N, Talbot J, Kurian M, Kumar J & Stephenson JBP (2004) Further examples of Coats' plus; expanding the phenotype. JOURNAL OF MEDICAL GENETICS, Vol. 41 (pp S43-S43) RIS download Bibtex download
  • Bishop N (2003) Osteoporosis in children with rheumatic disease. ANNALS OF THE RHEUMATIC DISEASES, Vol. 62 (pp 14-14) RIS download Bibtex download
  • Holmes SG, Buttle DJ, Bishop NJ & Grabowski PS (2003) Matrix metalloproteinase inhibition does not recapitulate the action of chemically modified tetracyclines on osteoclast lineage cells. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 18(7) (pp 1359-1359) RIS download Bibtex download
  • Bishop NJ (2003) Growing bones - A famework for the future. PEDIATRIC RESEARCH, Vol. 53(6) (pp 5A-5A) RIS download Bibtex download
  • McMahon R, Holden MJ, Afafi A, Bishop N & Dalton A (2002) A diagnostic assay for COL1A1 expression levels in Osteogenesis Imperfecta patients.. JOURNAL OF MEDICAL GENETICS, Vol. 39 (pp S81-S81) RIS download Bibtex download
  • van Staa TP, Cooper C, Leufkens HGM & Bishop N (2002) Children and the risk of fractures due to oral corticosteroids.. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 17 (pp S171-S171) RIS download Bibtex download
  • Ladele A, Arikoski P, Grabowski PS & Bishop NJ (2002) Heterogeneity of RANK-L expression in bone marrow of patients with acute lymphoblastic leukaemia. BONE, Vol. 30(3) (pp 29S-29S) RIS download Bibtex download
  • Edwards TP, Bishop NJ & Grabowski PS (2002) Failure of osteoclast induction from peripheral blood in a child with osteopetrosis. BONE, Vol. 30(3) (pp 16S-16S) RIS download Bibtex download
  • Holmes SG, Still K, Reading L, Bishop NJ & Grabowski PS (2002) Inhibition of osteoclast and CFU-f development in culture with chemically modified tetracyclines. BONE, Vol. 30(3) (pp 18S-18S) RIS download Bibtex download
  • Salle BL, Delvin EE, Lapillonne A, Bishop NJ & Glorieux FH (2000) Perinatal metabolism of vitamin D. AMERICAN JOURNAL OF CLINICAL NUTRITION, Vol. 71(5) (pp 1317S-1324S) RIS download Bibtex download
  • Bishop NJ (1995) Skeletal growth and development in infants born preterm: Effect of early diet. Monatsschrift fur Kinderheilkunde, Vol. 143(7 SUPPL. 2) RIS download Bibtex download
  • Bishop NJ (1992) Aluminium in infant feeding: Is it a problem?. European Journal of Clinical Nutrition, Vol. 46(SUPPL. 4) RIS download Bibtex download
  • Bishop NJ (1992) Bone growth and mineralisation in preterm infants. Pediatric Reviews and Communications, Vol. 6(3) (pp 181-183) RIS download Bibtex download
  • Devaraja J, Dimitri P, Paggiosi M, Clark C, Jacques R & Bishop N () Impact of type 1 diabetes mellitus on skeletal integrity and strength in adolescents aged 12 to 16 years; as assessed by High Resolution peripheral Quantitative Computed Tomography (HRpQCT). Bone Abstracts RIS download Bibtex download
  • Bishop N, Kalajzic I, Arshad F, Lefley D, Gossiel F & Ottewell P () Losartan reduces circulating TGFb and CTX and increases vertebral bone mass in the OIM mouse. Bone Abstracts RIS download Bibtex download
  • Arshad F, Lefley D, Madan S, Fernandes J, Bishop N & Ottewell P () Developing a human-mouse hybrid model of osteogenesis imperfecta for investigating new therapies for children. Bone Abstracts RIS download Bibtex download
  • Gopal KJS, Sritharan S, Jacques R, Bishop N & Dimitri P () Increase in lean mass may augment gains in bone mass and size in patients with osteogenesis imperfecta treated with bisphosphonates. Endocrine Abstracts RIS download Bibtex download

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