Mr Matthew Fisher

BSc (Hons)

School of Medicine and Population Health

Technical Specialist – BSU

matthew.fisher@sheffield.ac.uk
+44 114 215 9067

GU36, The Medical School

Full contact details

Mr Matthew Fisher
School of Medicine and Population Health
GU36
The Medical School
Beech Hill Road
Sheffield
S10 2RX

Research interests: The TMG study the blood vessels that supply tumours with oxygen and nutrients and their role in cancer therapy. Tumours require a blood supply to grow and the blood vessels provide a route for the spread of tumour cells to other sites in the body. Therefore, targeting treatment to the blood vessels rather than the tumour cells is a potential means of killing tumours. Much of the research involves using vascular disrupting agents (VDAs) e.g. CA4P, and the susceptibility of tumour vessels to vascular shutdown.

Publications

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Mironov A, Fisher M, Narayanan P, Elsayed R, Karabulutoglu M & Akhtar N (2023) Rac1 controls cell turnover and reversibility of the involution process in postpartum mammary glands. PLoS Biology, 21(1).
English WR, Lunt SJ, Fisher M, Lefley DV, Dhingra M, Lee Y-C, Bingham K, Hurrell JE, Lyons SK, Kanthou C & Tozer GM (2017) Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma. Cancer Research, 77(10). View this article in WRRO

Valluru MK, Mukherjee D, Fisher M, Madrigal-Esquivel C, Bradford J, Kanthou C, Tozer GM & English WR (2019) VEGFA isoform switching in soft tissue sarcoma is associated with decreased survival. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 100(4) (pp A41-A41)

Mironov A, Fisher M, Elsayed R, Karabulutoglu M & Akhtar N (2022) Rac1 controls cell turnover and mammary gland reversibility in post-partum involution, Cold Spring Harbor Laboratory.