Dr Margaret Paggiosi

All publications

Journal articles

• Handforth C, Paggiosi MA, Jacques R, Gossiel F, Eastell R, Walsh JS & Brown JE (2024) The impact of androgen deprivation therapy on bone microarchitecture in men with prostate cancer: A longitudinal observational study (The ANTELOPE Study). Journal of Bone Oncology, 47. View this article in WRRO
• Brown J, Paggiosi M, Rathbone E, Dodwell D, Cameron D, Gregory W, Eastell R & Coleman R (2024) BoHFAB. The impact of adjuvant zoledronate therapy on bone health in postmenopausal patients with early breast cancer. Journal of Bone Oncology, 45, 100529-100529.
• Aldieri A, Paggiosi M, Eastell R, Bignardi C, Audenino AL, Bhattacharya P & Terzini M (2024) DXA-based statistical models of shape and intensity outperform aBMD hip fracture prediction: A retrospective study. Bone, 182, 117051-117051.
• Vilaca T, Evans A, Gossiel F, Paggiosi M, Eastell R & Walsh JS (2022) Fat, adipokines, bone structure and bone regulatory factors associations in obesity. European Journal of Endocrinology.
• Aldieri A, Terzini M, Audenino AL, Bignardi C, Paggiosi M, Eastell R, Viceconti M & Bhattacharya P (2022) Personalised 3D assessment of trochanteric soft tissues improves HIP fracture classification accuracy. Annals of Biomedical Engineering, 50(3), 303-313. View this article in WRRO
• Aldieri A, Bhattacharya P, Paggiosi M, Eastell R, Audenino AL, Bignardi C, Morbiducci U & Terzini M (2022) Improving the hip fracture risk prediction with a statistical shape-and-intensity model of the proximal femur. Annals of Biomedical Engineering, 50(2), 211-221.
• Vilaca T, Paggiosi M, Walsh JS, Selvarajah D & Eastell R (2021) The Effects of Type 1 Diabetes and Diabetic Peripheral Neuropathy on the Musculoskeletal System: A Case-Control Study.. J Bone Miner Res.
• Paggiosi M, Naganathan DGN, Undre U, Peel N & Eastell R (2021) Are non-fracture vertebral deformities more prevalent in patients with osteoporotic vertebral fractures?. Bone Reports, 14, 101050.
• Montefiori E, Kalkman B, Henson W, Paggiosi M, McCloskey E & Mazza C (2020) MRI-based anatomical characterisation of lower-limb muscles in older women. PLoS ONE, 15(12). View this article in WRRO
• Salam S, Gallagher O, Gossiel F, Paggiosi M, Eastell R & Khwaja A (2020) Vascular calcification relationship to vascular biomarkers and bone metabolism in advanced chronic kidney disease. Bone, 115699-115699.
• Devaraja J, Jacques R, Paggiosi M, Clark C & Dimitri P (2020) Impact of Type 1 diabetes mellitus on skeletal integrity and strength in adolescents as assessed by HRpQCT. JBMR Plus. View this article in WRRO
• Vilaca T, Paggiosi M, Walsh J, Selvarajah D & Eastell R (2020) Bone peripheral microarchitecture in type 1 diabetes with and without neuropathy; a cross-section study. Bone Reports, 13, 100642-100642.
• Paggiosi MA, Peel N, McCloskey E, Walsh JS & Eastell R (2020) Comparison of treatment responder rates for three oral bisphosphonates: The TRIO study. Bone Reports, 13, 100677-100677.
• Paggiosi MA, Debono M, Walsh JS, Peel NFA & Eastell R (2020) Quantitative computed tomography discriminates between postmenopausal women with low spine bone mineral density with vertebral fractures and those with low spine bone mineral density only: the SHATTER study. Osteoporosis International, 31(4), 667-675.
• Gossiel F, Paggiosi MA, Naylor KE, McCloskey EV, Walsh J, Peel N & Eastell R (2020) The effect of bisphosphosphonates on bone turnover and bone balance in postmenopausal women with osteoporosis: The T-score bone marker approach in the TRIO study. Bone, 131.
• Du J, Brooke-Wavell K, Paggiosi MA, Hartley C, Walsh JS, Silberschmidt VV & Li S (2019) Characterising variability and regional correlations of microstructure and mechanical competence of human tibial trabecular bone: An in-vivo HR-pQCT study.. BONE, 121, 139-148. View this article in WRRO
• Naylor KE, McCloskey EV, Jacques RM, Peel NFA, Paggiosi MA, Gossiel F, Walsh JS & Eastell R (2019) Clinical utility of bone turnover markers in monitoring the withdrawal of treatment with oral bisphosphonates in postmenopausal osteoporosis. Osteoporosis International. View this article in WRRO
• Naylor KE, Bradburn M, Paggiosi MA, Gossiel F, Peel NFA, McCloskey EV, Walsh JS & Eastell R (2018) Effects of discontinuing oral bisphosphonate treatments for postmenopausal osteoporosis on bone turnover markers and bone density. Osteoporosis International, 29(6), 1407-1417. View this article in WRRO
• Salam S, Gallagher O, Gossiel F, Paggiosi M, Khwaja A & Eastell R (2018) Diagnostic Accuracy of Biomarkers and Imaging for Bone Turnover in Renal Osteodystrophy.. Journal of the American Society of Nephrology. View this article in WRRO
• Paggiosi MA, Yang L, Blackwell D, Walsh JS, McCloskey E, Peel N & Eastell R (2018) Teriparatide treatment exerts differential effects on the central and peripheral skeleton: results from the MOAT study. Osteoporosis International, 29(6), 1367-1378. View this article in WRRO
• Gossiel F, Scott JR, Paggiosi MA, Naylor KE, McCloskey EV, Peel NFA, Walsh JS & Eastell R (2018) The effect of teriparatide treatment on circulating periostin and its relationship to regulators of bone formation and BMD in postmenopausal women with osteoporosis.. Journal of Clinical Endocrinology and Metabolism. View this article in WRRO
• Metcalf LM, Dall'Ara E, Paggiosi MA, Rochester JR, Vilayphiou N, Kemp GJ & McCloskey EV (2018) Validation of calcaneus trabecular microstructure measurements by HR-pQCT. Bone, 106, 69-77. View this article in WRRO
• Walsh JS, Gossiel F, Scott JR, Paggiosi MA & Eastell R (2017) Effect of age and gender on serum periostin: Relationship to cortical measures, bone turnover and hormones. Bone, 99, 8-13. View this article in WRRO
• Digby MG, Bishop NJ, Paggiosi MA & Offiah AC (2016) HR-pQCT: a non-invasive 'biopsy' to assess bone structure and strength.. Arch Dis Child Educ Pract Ed, 101, 268-270. View this article in WRRO
• Gregson CL, Wheeler L, Hardcastle SA, Appleton LH, Addison KA, Brugmans M, Clark GR, Ward KA, Paggiosi M, Stone M , Thomas J et al (2016) Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass Cases. Journal of Bone and Mineral Research, 31(3), 640-649. View this article in WRRO
• Naylor KE, Jacques RM, Paggiosi M, Gossiel F, Peel NFA, McCloskey EV, Walsh JS & Eastell R (2016) Response of bone turnover markers to three oral bisphosphonate therapies in postmenopausal osteoporosis: the TRIO study. Osteoporosis International, 27(1), 21-31. View this article in WRRO
• Naylor KE, Jacques RM, Paggiosi M, Gossiel F, Peel NF, McCloskey EV, Walsh JS & Eastell R (2016) Bone turnover markers: response to comments by Seeman and Nguyen. Osteoporosis International, 27(1), 37-37. View this article in WRRO
• Evans AL, Paggiosi MA, Eastell R & Walsh JS (2015) Bone Density, Microstructure and Strength in Obese and Normal Weight Men and Women in Younger and Older Adulthood. Journal of Bone and Mineral Research, 30(5), 920-928. View this article in WRRO
• Paggiosi MA, Peel NFA & Eastell R (2015) The impact of glucocorticoid therapy on trabecular bone score in older women. Osteoporosis International, 26(6), 1773-1780. View this article in WRRO
• Dimitri P, Jacques RM, Paggiosi M, King D, Walsh J, Taylor ZA, Frangi AF, Bishop N & Eastell R (2015) Leptin May Play a Role in Bone Microstructural Alterations in Obese Children. The Journal of Clinical Endocrinology & Metabolism, 100(2), 594-602. View this article in WRRO
• Paggiosi MA, Peel N, McCloskey E, Walsh JS & Eastell R (2014) Comparison of the effects of three oral bisphosphonate therapies on the peripheral skeleton in postmenopausal osteoporosis: the TRIO study. Osteoporosis International, 25(12), 2729-2741.
• Paggiosi MA, Eastell R & Walsh JS (2014) Precision of high-resolution peripheral quantitative computed tomography measurement variables: influence of gender, examination site, and age.. Calcif Tissue Int, 94(2), 191-201.
• Gregson CL, Paggiosi MA, Crabtree N, Steel SA, McCloskey E, Duncan EL, Fan B, Shepherd JA, Fraser WD, Smith GD & Tobias JH (2013) Analysis of body composition in individuals with high bone mass reveals a marked increase in fat mass in women but not men.. J Clin Endocrinol Metab, 98(2), 818-828.
• Finigan J, Naylor K, Paggiosi MA, Peel NF & Eastell R (2013) Adherence to raloxifene therapy: assessment methods and relationship with efficacy. OSTEOPOROSIS INTERNATIONAL, 24(11), 2879-2886.
• Walsh JS, Paggiosi MA & Eastell R (2012) Cortical consolidation of the radius and tibia in young men and women.. J Clin Endocrinol Metab, 97(9), 3342-3348.
• Paggiosi MA, Finigan J, Peel N, Eastell R & Ferrar L (2012) Supine vs decubitus lateral patient positioning in vertebral fracture assessment.. J Clin Densitom, 15(4), 454-460.
• Paggiosi MA, Barkmann R, Glüer CC, Roux C, Reid DM, Felsenberg D, Bradburn M & Eastell R (2012) A European multicenter comparison of quantitative ultrasound measurement variables: the OPUS study.. Osteoporos Int, 23(12), 2815-2828.
• Paggiosi MA, Glueer CC, Roux C, Reid DM, Felsenberg D, Barkmann R & Eastell R (2011) International variation in proximal femur bone mineral density.. Osteoporos Int, 22(2), 721-729.
• Naylor KE, Clowes JA, Finigan J, Paggiosi MA, Peel NFA & Eastell R (2010) The effect of cessation of raloxifene treatment on bone turnover in postmenopausal women.. Bone, 46(3), 592-597.
• Paggiosi MA, Clowes JA, Finigan J, Naylor KE & Peel NF (2010) Performance of quantitative ultrasound measurements of bone for monitoring raloxifine therapy. Journal of Clinical Densitometry, 13(4), 441-450.
• Paggiosi MA, Blumsohn A, Barkmann R & Eastell R (2005) Effect of temperature on the longitudinal variability of quantitative ultrasound variables.. J Clin Densitom, 8(4), 436-444.
• Walle M, Duseja A, Whittier DE, Vilaca T, Paggiosi M, Eastell R, Müller R & Collins CJ () Bone remodelling and responsiveness to mechanical stimuli in individuals with type 1 diabetes mellitus. Journal of Bone and Mineral Research.
• Brown J, Paggiosi MA, Rathbone E, Gregory W, Bertelli G, Din O, McCloskey E, Dodwell D, Cameron D, Eastell R & Coleman R () Adjuvant bisphosphonate therapy and bone health. Journal of Bone and Mineral Research.
• Altai Z, Montefiori E, van Veen B, A. Paggiosi M, McCloskey EV, Viceconti M, Mazzà C & Li X () Femoral neck strain prediction during level walking using a combined musculoskeletal and finite element model approach. PLOS ONE, 16(2), e0245121-e0245121.
• Du J, Hartley C, Brooke-Wavell K, Paggiosi MA, Walsh JS, Li S & Silberschmidt VV () High-impact exercise stimulated localised adaptation of microarchitecture across distal tibia in postmenopausal women. Osteoporosis International.
• Dimitri P, Paggiosi M, King D, Bishop N & Eastell R () Leptin is associated with bone microstructural changes in obese children. Endocrine Abstracts.
• Naylor K, Paggiosi M, Gossiel F, McCloskey E, Peel N, Walsh J & Eastell R () Determinants of bone turnover marker response to three oral bisphosphonate therapies in postmenopausal osteoporosis: the TRIO study. Bone Abstracts.
• Gossiel F, Naylor K, McCloskey E, Peel N, Walsh J, Paggiosi M & Eastell R () The effect of bisphosphonate treatment on sclerostin levels in postmenopausal osteoporosis: the TRIO study. Bone Abstracts.
• Paggiosi M, Peel N & Eastell R () Diagnostic discrimination of TBS and spine BMD in glucocorticoid-induced and postmenopausal osteoporosis. Bone Abstracts.
• Fennimore DJ, Digby M, Paggiosi M, Arundel P, Bishop NJ, Dimitri P & Offiah AC () High-resolution peripheral quantitative computed tomography in children with osteogenesis imperfecta. Pediatric Radiology. View this article in WRRO

Conference proceedings papers

• Duseja A, Gossiel F, Paggiosi M, Walsh J, Frost M, Hermann P & Eastell R (2023) Bone turnover and bone balance in type 2 diabetes. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 38 (pp 312-312)
• Alshamrani HA, Paggiosi MA, Rigby AS, Bishop NJ & Offiah AC (2020) EFFECT OF HIGH DOSE VITAMIN D AND WHOLE BODY VIBRATION ON BONE DENSITY OF THE DISTAL TIBIA AS MEASURED BY HR-PQCT, SERUM 25(OH)D AND PTH. OSTEOPOROSIS INTERNATIONAL, Vol. 31(SUPPL 1) (pp S443-S444)
• Vilaca T, Paggiosi M, Gossiel F, Selvarajah D, Walsh J & Eastell R (2020) Bone Health in Type 1 Diabetes with and without Neuropathy; a Cross-Section Study. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 35 (pp 51-51)
• Salam S, Paggiosi M, Gallagher O, Eastell R & Khwaja A (2019) FP610 Vascular calcification in advanced CKD and its relationship with bone microstructures. Nephrology Dialysis Transplantation, Vol. 34(Supplement_1). Budapest, Hungary, 13 June 2019 - 16 June 2019. View this article in WRRO
• Salam S, Paggiosi M, Gallagher O, Eastell R & Khwaja A (2019) VASCULAR CALCIFICATION IN ADVANCED CKD AND ITS RELATIONSHIP WITH BONE MICROSTRUCTURES. NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol. 34
• Devaraja J, Dimitri P, Paggiosi M, Clark C, Jacques R & Bishop N () Impact of type 1 diabetes mellitus on skeletal integrity and strength in adolescents aged 12 to 16 years; as assessed by High Resolution peripheral Quantitative Computed Tomography (HRpQCT). Bone Abstracts

Datasets

• Tai ZA, Montefiori E, Veen BV, Paggiosi M, McCloskey E, Viceconti M, Mazza C & Li X Femoral neck strain prediction during level walking using a combined musculoskeletal and finite element model approach.
• Montefiori E, Kalkman B, Mazza C, Paggiosi M, McCloskey E & Henson W Data for paper "MRI-based anatomical characterisation of lower-limb muscles in older women".