Dr Khondoker Akram
Clinical Medicine, School of Medicine and Population Health
Postdoctoral Research Associate
k.m.akram@sheffield.ac.uk
+44 114 215 9666
+44 114 215 9666
JW4/11, Level 4, Jessop Wing
Full contact details
Dr Khondoker Akram
Clinical Medicine, School of Medicine and Population Health
JW4/11, Level 4
Jessop Wing
Tree Root Walk
Sheffield
S10 2SF
Clinical Medicine, School of Medicine and Population Health
JW4/11, Level 4
Jessop Wing
Tree Root Walk
Sheffield
S10 2SF
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Transcriptomic analysis of the human placenta reveals trophoblast dysfunction and augmented Wnt signalling associated with spontaneous preterm birth. Frontiers in Cell and Developmental Biology, 10. View this article in WRRO
- Impaired autophagy with augmented apoptosis in a Th1/Th2-imbalanced placental micromilieu is associated with spontaneous preterm birth. Frontiers in Molecular Biosciences, 9. View this article in WRRO
- Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour. Nature Communications, 10(1).
- An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection. Mucosal immunology, 11(-), 71-81. View this article in WRRO
- Lung Regeneration: Endogenous and Exogenous Stem Cell Mediated Therapeutic Approaches. International Journal of Molecular Sciences, 17(1), 128-128. View this article in WRRO
- Club cells inhibit alveolar epithelial wound repair via TRAIL-dependent apoptosis.. Eur Respir J, 41(3), 683-694.
- Mesenchymal stem cells promote alveolar epithelial cell wound repair in vitro through distinct migratory and paracrine mechanisms.. Respir Res, 14, 9.
- Mesenchymal stem cell therapy and lung diseases.. Adv Biochem Eng Biotechnol, 130, 105-129.
- The Planar Polarity Component VANGL2 Is a Key Regulator of Mechanosignaling. Frontiers in Cell and Developmental Biology, 8.
All publications
Journal articles
- Effects of warm environmental temperature on human placental transcriptomes in term and preterm births.
- Transcriptomic analysis of the human placenta reveals trophoblast dysfunction and augmented Wnt signalling associated with spontaneous preterm birth. Frontiers in Cell and Developmental Biology, 10. View this article in WRRO
- Impaired autophagy with augmented apoptosis in a Th1/Th2-imbalanced placental micromilieu is associated with spontaneous preterm birth. Frontiers in Molecular Biosciences, 9. View this article in WRRO
- Time-lapse Imaging of Alveologenesis in Mouse Precision-cut Lung Slices. BIO-PROTOCOL, 9(20).
- Live imaging of alveologenesis in precision-cut lung slices reveals dynamic epithelial cell behaviour. Nature Communications, 10(1).
- Erratum: An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection. Mucosal Immunology, 11(3), 1008-1008.
- An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection. Mucosal immunology, 11(-), 71-81. View this article in WRRO
- An in vitro model of murine middle ear epithelium.. Disease Models and Mechanisms, 9, 1405-1417. View this article in WRRO
- Lung Regeneration: Endogenous and Exogenous Stem Cell Mediated Therapeutic Approaches. International Journal of Molecular Sciences, 17(1), 128-128. View this article in WRRO
- BPIFA1: A Protein with an Important Role in the Inflammatory Response to Viral Infection in the Respiratory Tract. Journal of Comparative Pathology, 154(1), 76-76.
- BMP2 repression and optimized culture conditions promote human bone marrow-derived mesenchymal stem cell isolation. Regenerative Medicine, 10(2), 109-125.
- Activin-Directed Differentiation of Human Embryonic Stem Cells Differentially Modulates Alveolar Epithelial Wound Repair via Paracrine Mechanism. Stem Cell Discovery, 04(03), 67-82.
- Hydrogels for lung tissue engineering: Biomechanical properties of thin collagen-elastin constructs.. J Mech Behav Biomed Mater, 38, 251-259.
- Alveolar epithelial cells in idiopathic pulmonary fibrosis display upregulation of TRAIL, DR4 and DR5 expression with simultaneous preferential over-expression of pro-apoptotic marker p53. International Journal of Clinical and Experimental Pathology, 7(2), 552-564.
- Club cells inhibit alveolar epithelial wound repair via TRAIL-dependent apoptosis.. Eur Respir J, 41(3), 683-694.
- Mesenchymal stem cells promote alveolar epithelial cell wound repair in vitro through distinct migratory and paracrine mechanisms.. Respir Res, 14, 9.
- Mesenchymal stem cell therapy and lung diseases.. Adv Biochem Eng Biotechnol, 130, 105-129.
- Idiopathic pulmonary fibrosis: immunohistochemical analysis provides fresh insights into lung tissue remodelling with implications for novel prognostic markers.. Int J Clin Exp Pathol, 5(1), 58-71.
- The Planar Polarity Component VANGL2 Is a Key Regulator of Mechanosignaling. Frontiers in Cell and Developmental Biology, 8.
Chapters
- Isolation and Culture of Primary Mouse Middle Ear Epithelial Cells, Methods in Molecular Biology (pp. 157-168). Springer New York
Conference proceedings papers
- Shotgun Metagenomic Sequencing Reveals Distinct Virome Profiles in Term and Preterm Human Placenta. REPRODUCTIVE SCIENCES, Vol. 30 (pp 161A-161A)
- Transcriptomic Analysis of Human Placenta Reveals a Distinct Gene Expression Pattern Associated with Dysregulated Apoptosis and Autophagy Leading to Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 274A-274A)
- LSC Abstract – A systems biology approach to aid identification of the mechanisms employed by BPIFA1/SPLUNC1 to restrict influenza A virus infection in the lung. ERS Lung Science Conference 2016
- LSC Abstract – The expression and function of BPIFA1 in the pulmonary innate immune response to influenza A virus infection. 10.1 Respiratory Infections
- An innate defence role for BPIFA1/SPLUNC1 against influenza-A virus infection. 3.2 Airway Cell Biology and Immunopathology
- S70 Mesenchymal Stem Cell Conditioned Media (MSC-CM) Suppress Wnt-3A and TGF-β1-Induced Myofibroblastic Differentiation. Thorax, Vol. 67(Suppl 2) (pp A35-A36)
- S138 Clara cells inhibit alveolar epithelial wound repair through a TRAIL-dependent apoptosis mechanism. Thorax, Vol. 65(Suppl 4) (pp A62-A63)
Preprints