Professor Dilly Anumba
MBBS, FWACS, MD, FRCOG, LLM Medical Law
Clinical Medicine, School of Medicine and Population Health
Professor of Obstetrics and Gynaecology
Chair of Obstetrics and Gynaecology
Consultant in Obstetrics and Gynaecology
Subspecialist in Fetomaternal Medicine
+44 114 215 9707
Full contact details
Clinical Medicine, School of Medicine and Population Health
JW4/40, Level 4
Jessop Wing
Tree Root Walk
Sheffield
S10 2SF
- Profile
-
For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk
I joined the University of Sheffield in 2003 as Senior Clinical Lecturer and Honorary Consultant in Obstetrics and Fetal Medicine, following research and clinical training in Newcastle University and hospitals in Yorkshire and the Northern region.
I was accredited a specialist in Obstetrics and Gynaecology in 1999, and a subspecialist in Maternal and Fetal Medicine in 2001. Since 2003, I have maintained busy clinical (Obstetrics, Fetomaternal Medicine), research and teaching roles.
- Research interests
-
I investigate the physiology of human parturition, particularly the role of immunity and inflammation in term/preterm labour and pregnancy complications such as hypertension, fetal growth restriction and stillbirth. I am also investigating new techniques to predict preterm birth by the detection of cervical remodelling changes as well as changes in the vaginal microbiome and metabolome.
I run specialist clinics in Prenatal Diagnosis and Fetal Therapy, Prematurity Prevention, and High-Risk Pregnancy, all of which have research spin-offs.
Current projects:
04/2018-2021 NIHR Global Health Grant Global Health Group for Preterm birth prevention and management (PRIME), £2million, Chief Investigator and Research Group Director.
• 07/2018-2021 EPSRC Grant, Nonlinear analysis of EIS and metabolite data for preterm birth management. Co-investigator with ZQ Lang £600k
• 04/2018-2021 NIHR Health Technology Assessment 16/16/06: COPE Randomised Control Trial, Management of postpartum haemorrhage, £1.8million. Co-investigator with Professor Andrew Weeks (Liverpool) et al
• 2017- 2020 NIHR Invention for Innovation (i4i) Scheme. Developing and testing a clinical grade magnetic impedance spectroscopy device for assessment of the cervix in pregnant women to predict preterm birth. £792,753.00. Chief and Principal Investigator, with Dr T Healey, Professor S Dixon and S Walters, Mrs. M Oppenshaw
- Publications
-
Show: Featured publications All publications
Featured publications
Journal articles
- Impact of a school‐based nutrition educational intervention on knowledge related to iron deficiency anaemia in rural Karnataka, India: A mixed methods pre–post interventional study. BJOG: An International Journal of Obstetrics & Gynaecology. View this article in WRRO
- Attention for and awareness of anemia in adolescents in Karnataka, India: a qualitative study. PLOS ONE, 18(4). View this article in WRRO
- How are hospitals in England caring for women at risk of preterm birth in 2021? The influence of national guidance on preterm birth care in England: a national questionnaire. BMC Pregnancy and Childbirth, 23(1).
- The acceptability of cervical electrical impedance spectroscopy within a multi-modal preterm birth screening package: a mixed methods study. BMC Pregnancy and Childbirth, 22. View this article in WRRO
- Cervical tissue hydration level monitoring by a resonant microwave coaxial probe. Sensors, 22(23).
- Transcriptomic analysis of the human placenta reveals trophoblast dysfunction and augmented Wnt signalling associated with spontaneous preterm birth. Frontiers in Cell and Developmental Biology, 10.
- Impaired autophagy with augmented apoptosis in a Th1/Th2-imbalanced placental micromilieu is associated with spontaneous preterm birth. Frontiers in Molecular Biosciences, 9.
- The Tommy’s Clinical Decision Tool, a device for reducing the clinical impact of placental dysfunction and preterm birth : protocol for a mixed-methods early implementation evaluation study. BMC Pregnancy and Childbirth, 22(1).
- Shifting social norms and adolescent girls' access to sexual and reproductive health services and information in a South African township. Qualitative Health Research, 32(6), 1014-1026.
- Interventions for the prevention of spontaneous preterm birth : a scoping review of systematic reviews. BMJ Open, 12(5). View this article in WRRO
- Understanding the relationship between social determinants of health and maternal mortality. BJOG: An International Journal of Obstetrics & Gynaecology, 129(7), 1211-1228. View this article in WRRO
- The value of cervical electrical impedance spectroscopy to predict spontaneous preterm delivery in asymptomatic women: the ECCLIPPx prospective cohort study. Ultrasound in Obstetrics & Gynecology, 58(2), 293-302.
- Potential incorporation of novel cervical impedance spectroscopy assessment into existing clinical algorithms for predicting preterm birth. European Journal of Obstetrics & Gynecology and Reproductive Biology, 256, 523-524.
- Research prioritisation on prevention and management of preterm birth in low and middle-income countries (LMICs) with a special focus on Bangladesh using the Child Health and Nutrition Research Initiative (CHNRI) method. Journal of Global Health, 13.
All publications
Books
- Evidence Based Global Health Manual for Preterm Birth Risk Assessment. Springer International Publishing.
- Preface.
- Preface.
- Antenatal Disorders for the MRCOG and Beyond. Cambridge University Press.
Journal articles
- Fetal lower urinary tract obstruction: international Delphi consensus on management and core outcome set. Ultrasound in Obstetrics & Gynecology, 64(5), 635-650.
- Placental lesions in stillbirth following the Amsterdam consensus: A systematic review and meta-analysis. Placenta, 158, 23-37.
- Socioeconomic and ethnic disparities in preterm births in an English maternity setting: a population-based study of 1.3 million births. BMC Medicine, 22(1). View this article in WRRO
- FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregnancy – protocol for a prospective multicentre mixed-methods feasibility study. BMJ Open, 14(8), e080021-e080021.
- Effects of warm environmental temperature on human placental transcriptomes in term and preterm births.
- Diagnosis and management of selective fetal growth restriction in monochorionic twin pregnancies: A cross‐sectional international survey. BJOG: An International Journal of Obstetrics & Gynaecology.
- EJOG. Letter to the Editor. Brief communication. Preterm birth clinics: How successful are they to reduce preterm birth?. European Journal of Obstetrics & Gynecology and Reproductive Biology.
- Techniques for detecting cervical remodeling as a predictor for spontaneous preterm birth: current evidence and future research avenues in patients with multiple pregnancies. The Journal of Maternal-Fetal & Neonatal Medicine, 36(2).
- Editorial: dialogues on preterm birth—causes and consequences, prevention and mitigation. Frontiers in Global Women's Health, 4.
- Impact of a school‐based nutrition educational intervention on knowledge related to iron deficiency anaemia in rural Karnataka, India: A mixed methods pre–post interventional study. BJOG: An International Journal of Obstetrics & Gynaecology. View this article in WRRO
- Attention for and awareness of anemia in adolescents in Karnataka, India: a qualitative study. PLOS ONE, 18(4). View this article in WRRO
- A filter-predictor polynomial feature based machine learning approach to predicting preterm birth from cervical electrical impedance spectroscopy. Biomedical Signal Processing and Control, 80, 104345.
- How are hospitals in England caring for women at risk of preterm birth in 2021? The influence of national guidance on preterm birth care in England: a national questionnaire. BMC Pregnancy and Childbirth, 23(1).
- The acceptability of cervical electrical impedance spectroscopy within a multi-modal preterm birth screening package: a mixed methods study. BMC Pregnancy and Childbirth, 22. View this article in WRRO
- Cervical tissue hydration level monitoring by a resonant microwave coaxial probe. Sensors, 22(23).
- Transcriptomic analysis of the human placenta reveals trophoblast dysfunction and augmented Wnt signalling associated with spontaneous preterm birth. Frontiers in Cell and Developmental Biology, 10.
- Impaired autophagy with augmented apoptosis in a Th1/Th2-imbalanced placental micromilieu is associated with spontaneous preterm birth. Frontiers in Molecular Biosciences, 9.
- The Tommy’s Clinical Decision Tool, a device for reducing the clinical impact of placental dysfunction and preterm birth : protocol for a mixed-methods early implementation evaluation study. BMC Pregnancy and Childbirth, 22(1).
- Matrix metalloproteinase-induced cervical extracellular matrix remodelling in pregnancy and cervical cancer. Reproduction and Fertility.
- Exploring the antimicrobial properties of vaginal Lactobacillus crispatus against preterm birth-associated bacteria. Reproduction and Fertility, 3(3), L6-L8.
- Shifting social norms and adolescent girls' access to sexual and reproductive health services and information in a South African township. Qualitative Health Research, 32(6), 1014-1026.
- Interventions for the prevention of spontaneous preterm birth : a scoping review of systematic reviews. BMJ Open, 12(5). View this article in WRRO
- Understanding the relationship between social determinants of health and maternal mortality. BJOG: An International Journal of Obstetrics & Gynaecology, 129(7), 1211-1228. View this article in WRRO
- Mechanistic Insights into Immune Suppression and Evasion in Bacterial Vaginosis. Current Microbiology, 79(3).
- Spectral binning of cervicovaginal fluid metabolites improves prediction of spontaneous preterm birth and Lactobacillus species dominance. Reproduction and Fertility, 2(4), L4-L6.
- Pharmacokinetics and placental transfer of dolutegravir in pregnancy.. J Antimicrob Chemother.
- Agency under constraint: Adolescent accounts of pregnancy and motherhood in informal settlements in South Africa.. Glob Public Health, 1-14.
- Placental pathology in women with HIV. Placenta, 115, 27-36.
- Parvovirus b19 infection in pregnancy – A review. European Journal of Obstetrics & Gynecology and Reproductive Biology, 264, 358-362.
- The value of cervical electrical impedance spectroscopy to predict spontaneous preterm delivery in asymptomatic women: the ECCLIPPx prospective cohort study. Ultrasound in Obstetrics & Gynecology, 58(2), 293-302.
- The effect of COVID-19 on maternal newborn and child health (MNCH) services in Bangladesh, Nigeria and South Africa: call for a contextualised pandemic response in LMICs.. Int J Equity Health, 20(1), 77.
- Acute villitis and intravascular microorganisms in fetal vessels : a case report and literature review of an unusual histopathological finding. Pediatric and Developmental Pathology.
- Differential impact of antiretroviral therapy initiated before or during pregnancy on placenta pathology in HIV-positive women. AIDS, Publish Ahead of Print.
- Diabetogenically beneficial gut microbiota alterations in third trimester of pregnancy. Reproduction and Fertility, 2(1), R1-R12.
- Applying the WHO ICD-MM classification system to maternal deaths in a tertiary hospital in Nigeria: A retrospective analysis from 2014–2018. PLOS ONE, 16(1). View this article in WRRO
- Potential incorporation of novel cervical impedance spectroscopy assessment into existing clinical algorithms for predicting preterm birth. European Journal of Obstetrics & Gynecology and Reproductive Biology, 256, 523-524.
- The transmembrane G protein-coupled CXCR3 receptor-ligand system and maternal foetal allograft rejection. Placenta.
- Placental microbial–metabolite profiles and inflammatory mechanisms associated with preterm birth. Journal of Clinical Pathology. View this article in WRRO
- Is short-term-variation of fetal-heart-rate a better predictor of fetal acidaemia in labour? A feasibility study. PLoS ONE, 15(8). View this article in WRRO
- Obesity in pregnant women: a primary care perspective on pre-conception counselling and the role of supplements. British Journal of General Practice, 70(697), 417-418. View this article in WRRO
- Microbial dysbiosis-induced obesity: role of gut microbiota in homoeostasis of energy metabolism. British Journal of Nutrition, 123(10), 1127-1137. View this article in WRRO
- Management of reduced fetal movement: A comparative analysis of two audits at a tertiary care clinical service. European Journal of Obstetrics & Gynecology and Reproductive Biology, 248, 128-132.
- Differential cytokine and metabolite production by cervicovaginal epithelial cells infected with Lactobacillus crispatus and Ureaplasma urealyticum. Anaerobe, 62, 102101-102101.
- Infection/inflammation-associated preterm delivery within 14 days of presentation with symptoms of preterm labour : A multivariate predictive model. PLOS ONE, 14(9), 222455-222455. View this article in WRRO
- Polarization-sensitive optical coherence tomography with a conical beam scan for the investigation of birefringence and collagen alignment in the human cervix. Biomedical Optics Express, 10(8), 4190-4206. View this article in WRRO
- Results of full postmortem examination in a cohort of clinically unexplained stillbirths: undetected fetal growth restriction and placental insufficiency are prevalent findings. Journal of Perinatology, 39(9), 1196-1203.
- Is portable foetal electrocardiogram monitor feasible for foetal heart rate monitoring of small for gestational age foetuses in the home environment. Journal of Obstetrics and Gynaecology, 39(8), 1081-1086.
- Fetal imaging and diagnosis services in developing countries – A call to action. Tropical Journal of Obstetrics and Gynaecology, 36(1), 1-1.
- Spectroscopic techniques as potential screening tools for preterm birth: A review and an exploratory study. Applied Spectroscopy Reviews, 54(4), 348-367.
- Psychosocial Stress, Cortisol Levels, and Maintenance of Vaginal Health. Frontiers in Endocrinology, 9. View this article in WRRO
- Can Obstetric Risk Factors Predict Fetal Acidaemia at Birth? A Retrospective Case-Control Study. Journal of Pregnancy, 2018. View this article in WRRO
- Inhibition of sialidase activity and cellular invasion by the bacterial vaginosis pathogen Gardnerella vaginalis. Archives of Microbiology, 200(7), 1129-1133. View this article in WRRO
- Women’s experience of wearing a portable fetal-electrocardiogram device to monitor small-for-gestational age fetus in their home environment. Women's Health, 14. View this article in WRRO
- A guide to the RCOG Advanced Professional Module in Clinical Research. The Obstetrician & Gynaecologist, 20(3), 201-203.
- The Vaginal Microenvironment: The Physiologic Role of Lactobacilli. Frontiers in Medicine, 5. View this article in WRRO
- A tale of two pregnancies: A Critical Interpretive Synthesis of women's perceptions about delayed initiation of antenatal care. Women and Birth, 31(3), 220-231. View this article in WRRO
- Influence of Gestational Age at Initiation of Antihypertensive Therapy: Secondary Analysis of CHIPS Trial Data (Control of Hypertension in Pregnancy Study).. Hypertension, 71(6), 1170-1177. View this article in WRRO
- Mid-gestational changes in cervicovaginal fluid cytokine levels in asymptomatic pregnant women are predictive markers of inflammation-associated spontaneous preterm birth. Journal of Reproductive Immunology, 126, 1-10. View this article in WRRO
- Comparison of diurnal variations, gestational age and gender related differences in fetal heart rate (FHR) parameters between appropriate-for-gestational-age (AGA) and small-for-gestational-age (SGA) fetuses in the home environment. PLoS ONE, 13(3). View this article in WRRO
- Prediction of delivering a small for gestational age infant and adverse perinatal outcome in women with suspected pre-eclampsia.. Ultrasound in Obstetrics and Gynecology, 51(3), 387-395. View this article in WRRO
- Visualisation of the insertion of a membrane for the treatment of preterm rupture of fetal membranes using a synthetic model of a pregnant uterus. Journal of Biomaterials Applications, 33(2), 234-244.
- Imbalanced Angiogenesis in Peripartum Cardiomyopathy - Diagnostic Value of Placenta Growth Factor. Circulation Journal, 81(11), 1654-1661. View this article in WRRO
- Spontaneous Preterm Birth Is Associated with Differential Expression of Vaginal Metabolites by Lactobacilli-Dominated Microflora. Frontiers in Physiology, 8. View this article in WRRO
- Ligands of toll-like receptors 2/4 differentially alter markers of inflammation, adhesion and angiogenesis by monocytes from women with pre-eclampsia in co-culture with endothelial cells. Journal of Reproductive Immunology, 121, 26-33. View this article in WRRO
- Magnetic induction spectroscopy (MIS)-probe design for cervical tissue measurements.. Physiol Meas, 38(5), 729-744.
- Estradiol alters the immune-responsiveness of cervical epithelial cells stimulated with ligands of Toll-like receptors 2 and 4.. PLoS One, 12(3). View this article in WRRO
- Use of MRI in the diagnosis of fetal brain abnormalities in utero (MERIDIAN): a multicentre, prospective cohort study. The Lancet, 389(10068), 538-546. View this article in WRRO
- Women's views and postpartum follow-up in the CHIPS Trial (Control of Hypertension in Pregnancy Study). European Journal of Obstetrics & Gynecology and Reproductive Biology, 206, 105-113.
- Second Harmonic Generation microscopy reveals collagen fibres are more organised in the cervix of postmenopausal women. Reproductive Biology and Endocrinology, 14. View this article in WRRO
- Cervicovaginal fluid acetate: a metabolite marker of preterm birth in symptomatic pregnant women. Frontiers in Medicine, 3. View this article in WRRO
- The Cost Implications of Less Tight Versus Tight Control of Hypertension in Pregnancy (CHIPS Trial). Hypertension, 2016(68), 1049-1055. View this article in WRRO
- The CHIPS Randomized Controlled Trial (Control of Hypertension in Pregnancy Study) Is Severe Hypertension Just an Elevated Blood Pressure?. Hypertension, 68, 1153-1159. View this article in WRRO
- Diagnostic Biomarkers in Women With Suspected Preeclampsia in a Prospective Multicenter Study. Obstetrics & Gynecology, 128(2), 245-252.
- 29 Fibrinogen alters the expression of markers of inflammation, adhesion and angiogenesis by monocytes from women with pre-eclampsia in co-culture with vascular endothelial cells. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 6(3), 150-151.
- Skin disorders.
- Malignancy.
- Plate Section.
- Identifying metabolite markers for preterm birth in cervicovaginal fluid by magnetic resonance spectroscopy. Metabolomics, 12(4). View this article in WRRO
- “Does short-term variation in fetal heart rate predict fetal acidaemia?” A systematic review and meta-analysis. The Journal of Maternal-Fetal and Neonatal Medicine, 29(24), 4070-4077. View this article in WRRO
- Development of an implantable synthetic membrane for the treatment of preterm premature rupture of fetal membranes. Journal of Biomaterials Applications, 30(7), 995-1003.
- Deprivation and poor psychosocial support are key determinants of late antenatal presentation and poor fetal outcomes-a combined retrospective and prospective study. BMC Pregnancy and Childbirth, 15(1). View this article in WRRO
- Why do ‘high risk’ women book late or not at all for antenatal care?. British Journal of General Practice, 65(640), 574.1-574. View this article in WRRO
- Diagnostic accuracy of placental growth factor and ultrasound parameters to predict the small-for-gestational-age infant in women presenting with reduced symphysis-fundus height. Ultrasound in Obstetrics & Gynecology, 46(2), 182-190. View this article in WRRO
- Fibrinogen altered the expression of inflammation, adhesion and angiogenic markers in pre-eclampsia monocytes co-cultured with vascular endothelial cells. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 122, 24-24.
- Toll-like receptor 2 and 4 expression in the pregnant and non-pregnant human uterine cervix. Journal of Reproductive Immunology, 107, 43-51.
- Understanding delayed access to antenatal care: a qualitative interview study.. BMC Pregnancy Childbirth, 14, 207. View this article in WRRO
- PFM.41 Obstetric cholestasis: What is the future for its diagnosis and management.. Arch Dis Child Fetal Neonatal Ed, 99 Suppl 1, A95.
- PLD.26 The ECCLIPPx study: Electrical Impedance Prediction of Preterm Birth.. Arch Dis Child Fetal Neonatal Ed, 99 Suppl 1, A113-A116.
- PLD.14 Care of women at high risk of preterm labour: Survey of UK practice.. Arch Dis Child Fetal Neonatal Ed, 99 Suppl 1, A109-A112.
- Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients.. J Reprod Immunol, 103, 23-28.
- Diagnostic accuracy of placental growth factor in women with suspected preeclampsia: a prospective multicenter study.. Circulation, 128(19), 2121-2131.
- Can we predict pregnancies requiring intervention based on the area in which a woman lives?. European Journal of Public Health, 23(suppl_1).
- Errors in prenatal diagnosis.. Best Pract Res Clin Obstet Gynaecol, 27(4), 537-548.
- PF.54 Accuracy of Fetal Imaging For the Detection of Severe Abnormalities in Early Gestation. Archives of Disease in Childhood - Fetal and Neonatal Edition, 98(Suppl 1), A19.2-A19.
- PL.89 Functional Effects of Oestradiol on Cytokine Responses of Human Ectocervical Epithelial Cells to Toll-Like Receptor 2 and 4 Ligands. Archives of Disease in Childhood - Fetal and Neonatal Edition, 98(Suppl 1), A79.2-A79.
- PL.84 Short-Term Culture of Human Ecto-Cervical Epithelial Cells for Genomic, Proteomic and Functional Studies. Archives of Disease in Childhood - Fetal and Neonatal Edition, 98(Suppl 1), A78.1-A78.
- PP.21 The Effect of Factors of Social Exclusion on Access to Antenatal Care and the Subsequent Impact on Fetal Outcomes. Archives of Disease in Childhood - Fetal and Neonatal Edition, 98(Suppl 1), A87.3-A87.
- Dilemmas regarding the use of CMV-specific immunoglobulin in pregnancy.. J Clin Virol, 57(2), 95-97.
- OS006. Functional expression of endogenous ligands of Toll like receptor4 on monocytes and placentae from women during normal pregnancy andpre-eclampsia. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2(3), 178-178.
- Monocyte subpopulations in pregnancy complicated by pre-eclampsia demonstrate a pro-inflammatory phenotype and upregulated expression of Toll-like receptors 2 and 4. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 119(6), e2-e2.
- Why do women attend late for antenatal booking? a qualitative interview study exploring the perspectives of service users and stakeholders. part 1: the service users. Archives of Disease in Childhood - Fetal and Neonatal Edition, 97(Suppl 1), A113.3-A113.
- Why do women attend late for antenatal booking? a qualitative interview study exploring the perspectives of maternity health and social care stakeholders. Archives of Disease in Childhood - Fetal and Neonatal Edition, 97(Suppl 1), A117.4-A118.
- Prostaglandin-induced cervical remodelling in humans in the first trimester is associated with increased expression of specific tight junction, but not gap junction proteins.. J Transl Med, 10, 40. View this article in WRRO
- Monocyte Subpopulations in Pregnancy Complicated by Pre-Eclampsia Demonstrate a Pro-Inflammatory Phenotype and Altered Angiogenesis, Chemotaxis and Migration.. REPRODUCTIVE SCIENCES, 19(S3), 316A-316A.
- Monocyte subpopulations from pre-eclamptic patients are abnormally skewed and exhibit exaggerated responses to Toll-like receptor ligands.. PLoS One, 7(7), e42217. View this article in WRRO
- Routine antenatal anti-D prophylaxis in women who are Rh(D) negative: meta-analyses adjusted for differences in study design and quality.. PLoS One, 7(2), e30711. View this article in WRRO
- WHY DO WOMEN ATTEND LATE FOR ANTENATAL BOOKING? A QUALITATIVE INTERVIEW STUDY EXPLORING THE PERSPECTIVES OF SERVICE USERS AND STAKEHOLDERS. J EPIDEMIOL COMMUN H, 65.
- The effect of stress and anxiety associated with maternal prenatal diagnosis on feto-maternal attachment.. BMC Womens Health, 11, 33. View this article in WRRO
- Management Challenges of a Live 12-Week Sub-hepatic Intra-abdominal Pregnancy. Obstetric Anesthesia Digest, 31(2), 132-132.
- Structured review of validity of clinical definitions of hypoxic-ischaemic encephalopathy (HIE). Archives of Disease in Childhood - Fetal and Neonatal Edition, 96(Supplement 1), Fa26-Fa26.
- Training to scan: a national trainers ultrasound training survey. Archives of Disease in Childhood - Fetal and Neonatal Edition, 96(Supplement 1), Fa63-Fa63.
- Scanning for all: a national trainees ultrasound training survey. Archives of Disease in Childhood - Fetal and Neonatal Edition, 96(Supplement 1), Fa68-Fa68.
- The second twin: inter-twin delivery time, umbilical arterial PH and apgar scores. Archives of Disease in Childhood - Fetal and Neonatal Edition, 96(Supplement 1), Fa76-Fa76.
- Cervical Electrical Impedance Spectroscopy May Predict Preterm Delivery in Women at Risk. REPROD SCI, 18(3), 301A-301A.
- The Contribution of Cervical Histology and Matrix Proteins to Tissue Electrical Resistivity Derived by Impedance Spectroscopy. REPROD SCI, 18(3), 273A-273A.
- The development of two postnatal health instruments: one for mothers (M-PHI) and one for fathers (F-PHI) to measure health during the first year of parenting.. Qual Life Res, 20(7), 1011-1022.
- Infective endocarditis affecting the pulmonary valves in pregnant intravenous drug users.. J Obstet Gynaecol, 31(1), 78-80.
- P11 Toll-like receptors expression on monocyte subpopulations dysregulated in pre-eclampsia. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 1, S45-S45.
- P12 Service review of computerised CTG monitoring in a fetomaternal day care unit in the United Kingdom. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 1, S45-S45.
- The effect of stress and anxiety associated with maternal prenatal diagnosis on feto-maternal attachment. JOURNAL OF PSYCHOSOMATIC OBSTETRICS AND GYNECOLOGY, 31, 86-86.
- Circulating levels of matrix proteases and their inhibitors in pregnant women with and without a history of recurrent pregnancy loss.. Reprod Biol Endocrinol, 8, 62. View this article in WRRO
- Retrospective analysis of cytogenetic services in North Trent 1999-2009: meeting the challenges of the National Down's Syndrome Screening Programme. Archives of Disease in Childhood - Fetal and Neonatal Edition, 95(Supplement 1), Fa95-Fa96.
- Reproductive outcome after hysteroscopic septoplasty in patients with septate uterus - a retrospective cohort study and systematic review of the literature. Reproductive Biology and Endocrinology, 8(1).
- Management challenges of a live 12-week sub-hepatic intra-abdominal pregnancy.. BJOG, 117(3), 365-368.
- Predictive value of clinical and laboratory indices at first assessment in women referred with suspected gestational hypertension.. Hypertens Pregnancy, 29(2), 163-179.
- Serum relaxin levels are reduced in pregnant women with a history of recurrent miscarriage, and correlate with maternal uterine artery Doppler indices in first trimester.. Eur J Obstet Gynecol Reprod Biol, 147(1), 41-45. View this article in WRRO
- The role of cervical Electrical Impedance Spectroscopy in the prediction of the course and outcome of induced labour. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 116(10), 1410-1410.
- Serum Relaxin Levels Are Reduced in Pregnant Women with a History of Recurrent Miscarriage, and Correlate with Maternal Uterine Artery Doppler Indices. REPRODUCTIVE SCIENCES, 16(3), 255A-255A.
- Cranial vault defects: the description of three cases that illustrate a spectrum of anomalies.. Pediatr Dev Pathol, 12(2), 96-102.
- The role of cervical Electrical Impedance Spectroscopy in the prediction of the course and outcome of induced labour.. BMC Pregnancy Childbirth, 9, 40. View this article in WRRO
- Reproducibility and repeatability of measuring the electrical impedance of the pregnant human cervix-the effect of probe size and applied pressure.. Biomed Eng Online, 8, 10. View this article in WRRO
- Semi-quantitative analysis of TLR2 and TLR4 expression in the non-pregnant and pregnant cervix and the potential role of oestrogen. BJOG-INT J OBSTET GY, 115(1), 123-123.
- Fetal megalourethra associated with hypoplastic left heart and imperforate anus: a previously unreported association.. Clin Dysmorphol, 17(1), 47-51.
- Cervical weakness causing recurrent premature births: could this be familial?. J Obstet Gynaecol, 27(4), 430-431.
- PLUTO trial protocol: Percutaneous shunting for lower urinary tract obstruction randomised controlled trial. BJOG: An International Journal of Obstetrics and Gynaecology, 114(7).
- Management of women with a previous preterm birth. Obstetrics, Gynaecology and Reproductive Medicine, 17(6), 188-191.
- Electrical impedance spectroscopy of the cervix in non-pregnant and pregnant women.. Eur J Obstet Gynecol Reprod Biol, 129(2), 145-149.
- The OEIS complex: two case reports that illustrate the spectrum of abnormalities and a review of the literature.. Prenat Diagn, 26(3), 267-272.
- Critical appraisal of the literature - Its role in CPD. European Clinics in Obstetrics and Gynaecology, 1(4), 245-250.
- Comparison of human uterine cervical electrical impedance measurements derived using two tetrapolar probes of different sizes.. Biomed Eng Online, 5, 62. View this article in WRRO
- The costs to the NHS of multiple births after IVF treatment in the UK.. BJOG, 113(1), 21-25.
- Expression of the GTP-binding protein (Galphas) is repressed by the nuclear factor kappaB RelA subunit in human myometrium.. Endocrinology, 146(11), 4994-5002.
- Characterization of Toll-like receptors in the female reproductive tract in humans.. Hum Reprod, 20(5), 1372-1378.
- The small baby on gestational ultrasound. Current Obstetrics and Gynaecology, 15(5), 334-342.
- Placental mesenchymal dysplasia associated with fetal aneuploidy.. Prenat Diagn, 25(3), 187-192.
- Diagnosis and outcome of fetal lower urinary tract obstruction in the northern region of England.. Prenat Diagn, 25(1), 7-13.
- The small baby on gestational ultrasound scan. Current Obstetrics & Gynaecology, 12(5), 286-292.
- Flow-mediated nitric oxide activity in the forearm vasculature of premenopausal women.. Br J Clin Pharmacol, 53(3), 332-336.
- The small baby on gestational ultrasound scan. Current Obstetrics and Gynaecology, 12(5), 286-292.
- Nitric oxide signaling mechanisms in the forearm vasculature of pregnant women.. Am J Obstet Gynecol, 185(2), 420.
- Nitric oxide activity in the peripheral vasculature during normotensive and preeclamptic pregnancy.. Am J Physiol, 277(2), H848-H854.
- Management of pre-eclampsia and haemolysis, elevated liver enzymes, and low platelets syndrome.. Curr Opin Obstet Gynecol, 11(2), 149-156.
- Contribution of nitric oxide to beta2-adrenoceptor mediated vasodilatation in human forearm arterial vasculature.. Br J Clin Pharmacol, 47(2), 173-177.
- Stimulated nitric oxide release and nitric oxide sensitivity in forearm arterial vasculature during normotensive and preeclamptic pregnancy.. Am J Obstet Gynecol, 181(6), 1479-1484.
- Nitric oxide contributes to beta(2)-adrenoceptor mediated vasodilatation in human forearm.. CLINICAL PHARMACOLOGY & THERAPEUTICS, 61(2), PIV48-PIV48.
- The role of nitric oxide in the modulation of vascular tone in normal pregnancy and preeclampsia. American Journal of Obstetrics and Gynecology, 176(1), S14-S14.
2 -adrenoceptor mediated vasodilatation in human forearm. Clinical Pharmacology and Therapeutics, 61(2), 230.
Nitric oxide contributes to β- Reproductive performance of two generations of women with marfan's syndrome. Journal of Obstetrics and Gynaecology, 14(6), 401-404.
- Developing a logistic regression model to predict spontaneous preterm birth from maternal socio-demographic and obstetric history at initial pregnancy registration. BMC Pregnancy and Childbirth, 24(1).
- Gestation-dependent increase in cervicovaginal pro-inflammatory cytokines and cervical extracellular matrix proteins is associated with spontaneous preterm delivery within 2 weeks of index assessment in South African women. Frontiers in Immunology, 15.
FIGO good practice recommendations on optimizing models of care for the prevention and mitigation of preterm birth. International Journal of Gynecology & Obstetrics.- Perception and experiences of adolescent mothers and communities in caring for their preterm babies: findings from an in-depth study in rural Bangladesh. BMC Pregnancy and Childbirth, 24(1).
- Research prioritisation on prevention and management of preterm birth in low and middle-income countries (LMICs) with a special focus on Bangladesh using the Child Health and Nutrition Research Initiative (CHNRI) method. Journal of Global Health, 13.
- Maternal obesity-related placental dysfunction: From peri-conception to late gestation. Placenta and Reproductive Medicine, 2.
- Ureaplasma parvum infection induces inflammatory changes in vaginal epithelial cells independent of sialidase. Molecular Biology Reports.
- A socio-ecological approach to understanding the factors influencing the uptake of intermittent preventive treatment of malaria in pregnancy (IPTp) in South-Western Nigeria. PLOS ONE, 16(3), e0248412-e0248412.
- Female Gut and Genital Tract Microbiota-Induced Crosstalk and Differential Effects of Short-Chain Fatty Acids on Immune Sequelae. Frontiers in Immunology, 11.
- Associating antiretroviral therapy initiated before or during pregnancy with placenta pathology in HIV infected women..
- Differential vaginal Lactobacillus species metabolism of glucose, L and D-lactate by 13C-nuclear magnetic resonance spectroscopy.
- Postnatal pelvic floor muscle stiffness measured by vaginal elastometry in women with obstetric anal sphincter injury : a pilot study. International Urogynecology Journal. View this article in WRRO
- A Combination of Cervicovaginal Fluid Glutamate, Acetate and D-Lactate Identified Asymptomatic Low-Risk Women Destined to Deliver Preterm: a Prospective Cohort Study. Reproductive Sciences.
- .
Chapters
- Electrical Impedance Spectroscopy Based Preterm Birth Prediction with Machine Learning, Lecture Notes in Computer Science (pp. 85-97). Springer Nature Switzerland
- Pregnancy Dating Guidance, Evidence Based Global Health Manual for Preterm Birth Risk Assessment (pp. 25-29). Springer International Publishing
- Prenatal Risk Assessment for Preterm Birth in Low-Resource Settings: Demographics and Obstetric History, Evidence Based Global Health Manual for Preterm Birth Risk Assessment (pp. 15-23). Springer International Publishing
- Global Antenatal Care Coverage and Content, Evidence Based Global Health Manual for Preterm Birth Risk Assessment (pp. 1-5). Springer International Publishing
- Ethics, Liability, and Risk Management in Obstetrics and Gynaecology, Contemporary Obstetrics and Gynecology for Developing Countries (pp. 723-736). Springer International Publishing
- Prenatal Screening and Diagnosis, Medicolegal Issues in Obstetrics and Gynaecology (pp. 85-87). Springer International Publishing
- The 20-Week Anomaly Scan, Medicolegal Issues in Obstetrics and Gynaecology (pp. 89-92). Springer International Publishing
- Common medical disorders in pregnancy, Antenatal Disorders for the MRCOG and Beyond (pp. 93-142). Cambridge University Press
- Antepartum haemorrhage, Antenatal Disorders for the MRCOG and Beyond (pp. 13-26). Cambridge University Press
- Drug and alcohol misuse in pregnancy, Antenatal Disorders for the MRCOG and Beyond (pp. 169-188). Cambridge University Press
- Endocrine disorders Cambridge University Press
- Gastrointestinal and hepatic disease Cambridge University Press
- Haematological disorders Cambridge University Press
- Kidney disease Cambridge University Press
- Maternal mental health disorders, Antenatal Disorders for the MRCOG and Beyond (pp. 159-168). Cambridge University Press
- Obesity Cambridge University Press
- Previous caesarean section, Antenatal Disorders for the MRCOG and Beyond (pp. 81-92). Cambridge University Press
- Alloimmunization in pregnancy, Antenatal Disorders for the MRCOG and Beyond (pp. 149-158). Cambridge University Press
- Cardiac disease in pregnancy, Antenatal Disorders for the MRCOG and Beyond (pp. 143-148). Cambridge University Press
- Multiple pregnancy, Antenatal Disorders for the MRCOG and Beyond (pp. 27-38). Cambridge University Press
- Hypertensive disorders in pregnancy, Antenatal Disorders for the MRCOG and Beyond (pp. 39-62). Cambridge University Press
- Antenatal Disorders for the MRCOG and Beyond Second Edition Preface, ANTENATAL DISORDERS FOR THE MRCOG AND BEYOND, 2ND EDITION (pp. IX-IX).
- Prematurity, Antenatal Disorders for the MRCOG and Beyond (pp. 63-80). Cambridge University Press
- Screening for fetal anomalies, Antenatal Disorders for the MRCOG and Beyond (pp. 189-196). Cambridge University Press
- Antenatal care and risk assessment, Antenatal Disorders for the MRCOG and Beyond (pp. 1-12). Cambridge University Press
Conference proceedings papers
- Optical design and simulation of a cervical scanning probe for polarization-sensitive optical coherence tomography using Ansys Zemax OpticStudio. Optical Coherence Imaging Techniques and Imaging in Scattering Media V, 25 July 2023 - 30 July 2023.
- Category ‐ Innovation. BJOG: An International Journal of Obstetrics & Gynaecology, Vol. 130(S2) (pp 101-109)
- Near-miss audit of SGA babies not detected during antenatal surveillance. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 130 (pp 209-210)
- Elevated Cervicovaginal Fluid Pro-Inflammatory Cytokines Predict Spontaneous Preterm Labour in Multiple Pregnancies. REPRODUCTIVE SCIENCES, Vol. 30 (pp 108A-109A)
- Metabolic Characteristics of Vaginal Dysbiosis Associated Bacteria: Mobiluncus curtisii and Lactobacillus iners. REPRODUCTIVE SCIENCES, Vol. 30 (pp 192A-192A)
- Cervicovaginal Fluid Markers of Inflammation and Extracellular Matrix Remodelling in Pregnant South African Women at High Risk of Spontaneous Preterm Birth. REPRODUCTIVE SCIENCES, Vol. 30 (pp 47A-47A)
- Ureaplasma parvum Infection Induces Inflammatory Changes in Vaginal Epithelial Cells Independent of Sialidase. REPRODUCTIVE SCIENCES, Vol. 30 (pp 190A-190A)
- Shotgun Metagenomic Sequencing Reveals Distinct Virome Profiles in Term and Preterm Human Placenta. REPRODUCTIVE SCIENCES, Vol. 30 (pp 161A-161A)
- Preterm birth clinic: Improved neonatal outcomes with better targeted interventions. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 130 (pp 175-175)
- Tommy's Clinical Decision Tool (Tommy's App): Early adopter implementation evaluation. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 130 (pp 101-102)
- Prediction of spontaneous preterm birth from routinely collected clinical data. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 130 (pp 209-210)
- High Stage and Grade of Maternal and Fetal Inflammatory Responses Are Associated with Low Placental CXCL10.. REPRODUCTIVE SCIENCES, Vol. 29(SUPPL 1) (pp 253-253)
- Increasing Cervicovaginal CXCL10 Across Mid-Trimester Predicted Women Destined to Deliver Preterm. REPRODUCTIVE SCIENCES, Vol. 29(SUPPL 1) (pp 200-201)
- Asymptomatic Women with Preterm Birth Have Distinct Cervicovaginal Metabolite Profile Across the Second Trimester. REPRODUCTIVE SCIENCES, Vol. 29(SUPPL 1) (pp 194-194)
- Metabolic Profiling of Gardenerella vaginalis: A Vaginal Dysbiosis and Preterm Birth-Associated Bacteria.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 215A-216A)
- Differential Vaginal Lactobacillus Species Metabolism of Glucose, L- and D-lactate by(13)C-Nuclear Magnetic Resonance Spectroscopy.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 216A-216A)
- Mid-Trimester Changes in Cervicovaginal Metabolites Are Distinct in Women with and without Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 114A-114A)
- Full Length Sequencing of Cervicovaginal Microbiota Associated with Spontaneous Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 213A-213A)
- Research priority-setting: prevention and treatment of pre-eclampsia/eclampsia in resource limited settings. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 128 (pp 99-100)
- Transcriptomic Analysis of Human Placenta Reveals a Distinct Gene Expression Pattern Associated with Dysregulated Apoptosis and Autophagy Leading to Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 28(SUPPL 1) (pp 274A-274A)
- Differential Metabolic Profiles of Lactobacillus Species and Preterm Birth-associated Bacteria.. REPRODUCTIVE SCIENCES, Vol. 27(SUPPL 1) (pp 122A-122A)
- Multivariate predictive model for infection/inflammation-associated preterm birth within 12 weeks of presentation with symptoms of preterm labour. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 126 (pp 132-132)
- Prediction of spontaneous preterm delivery within two weeks of presentation with symptoms of threatened preterm labour: utility of cervicovaginal fluid pro-inflammatory mediators. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 126 (pp 133-134)
- Discriminative Capacity of H-1-MRS Spectrum Binning for Preterm Delivery-Associated Lactobacilli-Dominated Vaginal Microbiota.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 212A-212A)
- A midtrimester combination of cervicovaginal fluid glutamate, acetate, and D-lactate identified asymptomatic low-risk women destined to deliver preterm: a prospective cohort study. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 126 (pp 126-126)
- The Role of Human Endothelial Colony Forming Cells in the Vascular Supply and Expansion of SKOV3-cells in a Murine Artificial Organ Xenograft Model.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 109A-110A)
- Prognostic Utility of Cervicovaginal Fluid Pro-Inflammatory Cytokines for Risk of Preterm Delivery within Two Weeks of Presentation with Symptoms of Threatened Preterm Labour.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 301A-302A)
- Infection/ Inflammation-Associated Preterm Delivery within 7-14 Days of Presentation with Symptoms of Preterm Labour: A Bimodal Predictive Model.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 301A-301A)
- Polarisation-Sensitive Optical Coherence Tomography as a Potential Tool for Assessing the Orientation of Collagen Fibres in the Human Cervix.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 128A-128A)
- Differential Cytokine and Metabolite Expression by Cervicovaginal Epithelial Cells Infected with Lactobacillus Crispatus and Preterm Birth-Associated Bacteria.. REPRODUCTIVE SCIENCES, Vol. 26 (pp 212A-212A)
- In vitro characterization of collagen organization in the human cervix using polarization-sensitive optical coherence tomography (PS-OCT). Diseases in the Breast and Reproductive System V, 2 February 2019 - 7 February 2019.
- Polarization-sensitive swept-source optical coherence tomography for investigating depth, birefringence, depolarization and orientation of collagen structure of human cervix tissue. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII, 2 February 2019 - 7 February 2019.
- Digital Twins as the Next Phase of Cyber-Physical Systems in Construction. COMPUTING IN CIVIL ENGINEERING 2019: DATA, SENSING, AND ANALYTICS (pp 256-264)
- Combining cervicovaginal fluid metabolite and cervical electrical impedance spectroscopy assessments in mid-trimester improves prediction of preterm birth in asymptomatic pregnant women - towards multimodality screening. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 92-92)
- Vaginal epithelial cells co-cultured with Lactobacillus and anaerobes differentially express acetate and CXCL8. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 90-90)
- Cervical electrical impedance spectroscopy predicts preterm delivery in asymptomatic women - the ECCLIPPx (TM) studies. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 12-12)
- Raman spectroscopic analysis of cervicovaginal fluid as a predictive tool for spontaneous preterm birth. BJOG: An International Journal of Obstetrics and Gynaecology, Vol. 125(S2) (pp 108-109), 19 April 2018 - 20 April 2018. View this article in WRRO
- Towards "Multimodality Screening" for Preterm Birth - Cervicovaginal Fluid Metabolites May Enhance the Prediction of Preterm Birth by Cervical Electrical Impedance Spectroscopy. REPRODUCTIVE SCIENCES, Vol. 25 (pp 254A-254A)
- Women's Experiences of Incorporating Cervical Electrical Impedance Spectroscopy into Conventional Clinical Assessment of Risk of Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 186A-186A)
- Analysing Cervicovaginal Fluid Using Raman Spectroscopy as a Predictive Tool for Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 123A-123A)
- Electrical Impedance Spectroscopy Predicts Preterm Delivery in Asymptomatic Women.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 63A-63A)
- Nonlinear Logistic Regression Analysis of Electrical Impedance Spectroscopy Data Improves the Accuracy of Prediction of Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 113A-113A)
- Cervicovaginal Epithelial Cells Differentially Express Acetate and CXCL8 in Co-Culture with Preterm Birth-Associated Bacteria and Protective Lactobacillus Species.. REPRODUCTIVE SCIENCES, Vol. 25 (pp 187A-187A)
- Prevalence and clinical outcome of patients presenting with reduced fetal movements (RFM). BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 73-73)
- Can antenatal risk factors predict fetal acidaemia at birth? A retrospective case control study. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 10-11)
- Cervical electrical impedance spectroscopy and cervicovaginal fluid metabolite assays may offer a multi-modal approach to improved screening for preterm birth in midtrimester. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 92-92)
- What factors militate against the antenatal detection of serious fetal anomalies in a UK tertiary antenatal care centre - a service review.. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 125 (pp 43-43)
- The Mid-Gestational Changes in Cervicovaginal RANTES and IL-1 beta Correlate with Fetal Fibronectin in Asymptomatic Pregnant Women and Are Predictive Markers of Inflammation-Associated Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 24 (pp 108A-109A)
- Do Small for Gestational Age (SGA) Fetuses Also Exhibit Circadian Changes in Fetal Heart Rate Parameters as Do Appropriate for Gestational Age (AGA) Fetuses?. REPRODUCTIVE SCIENCES, Vol. 24 (pp 200A-200A)
- Mid-Trimester Changes in Cervicovaginal Fluid Cytokine Profile of Asymptomatic Women as Early Indicators of Preterm Birth.. REPRODUCTIVE SCIENCES, Vol. 24 (pp 237A-237A)
- Predictive markers of inflammation-associated preterm birth in asymptomatic pregnant women: correlation of mid-gestational changes in cervicovaginal RANTES and IL-1 beta with fetal fibronectin. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 124 (pp 126-127)
- High Pelvic Floor Muscle Stiffness Measured by Vaginal Elastometry Is a Risk Factor for Delayed Second Stage of Labour, Instrumental Vaginal Delivery and Pelvic Floor Damage. REPRODUCTIVE SCIENCES, Vol. 24 (pp 124A-124A)
- Prognostic Capacity of Cervicovaginal Fluid Acetate-Glutamate Ratio for Risk of Preterm Delivery within Two Weeks of Presentation with Symptoms of Preterm Labor.. REPRODUCTIVE SCIENCES, Vol. 24 (pp 175A-175A)
- Decreased cervicovaginal fluid glutamate improves the predictive value of acetate for risk of preterm delivery within two weeks of presentation with threatened preterm labour. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 124 (pp 127-127)
- Mid-trimester changes in cervicovaginal fluid cytokine profile of asymptomatic women at risk of preterm birth correlate with gestational changes in prevalence of bacterial vaginosis - associated organisms. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 124 (pp 131-131)
- A quantitative longitudinal cohort study of mothers' and their partners' health and well-being in the first year postpartum. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 123 (pp 42-42)
- Does short-term variation of the fetal heart rate accurately predict fetal acidaemia?. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 123 (pp 43-43)
- The Effect of Relaxin-2 and Tissue Inhibitors of Matrix Metalloproteinase-2 (TIMP-2) on the Expression Levels of Matrix Metalloproteinase-2 (MMP-2) by Co-Incubation of Endometrial Stromal and Trophoblast Cell Lines.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 335A-335A)
- The Association of Cervicovaginal Fluid Metabolites at 20-22 Weeks Gestation with Quantitative Fetal Fibronectin, Ultrasound Cervical Length and Gestational Age at Delivery in Asymptomatic Pregnant Women.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 190A-191A)
- The Use of Second-Harmonic-Generation (SHG) to Assess the Impact of Menopause on the Orientation of Collagen Fibres in the Human Cervix.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 214A-214A)
- Prognostic Microbiomial and Metabolite Markers of Preterm Birth in Second Trimester Cervicovaginal Fluid from Women at Risk.. REPRODUCTIVE SCIENCES, Vol. 23 (pp 128A-128A)
- Predicting Preterm Birth - The Performance of Ultrasound Cervical Length, Quantitative Fetal Fibronectin and Vaginal Fluid pH Differs by Risk of Preterm Birth and Symptoms of Preterm Labour. REPRODUCTIVE SCIENCES, Vol. 23 (pp 106A-106A)
- Elucidating Potential Metabolite Markers of Preterm Birth in Cervicovaginal Secretions By Nuclear Magnetic Resonance Spectroscopy. REPRODUCTIVE SCIENCES, Vol. 22 (pp 130A-130A)
- Using 3-D Models To Investigate Trophoblast-Endometrial Interactions In Vitro. REPRODUCTIVE SCIENCES, Vol. 22 (pp 226A-226A)
- Oestradiol Modulates Expression Levels of Toll-Like Receptor 2 and 4 in Human Ectocervical Epithelial Cells.. REPRODUCTIVE SCIENCES, Vol. 22 (pp 329A-329A)
- Assessing the Risk of Spontaneous Premature Birth By Electrical Impedance Spectroscopy of the Cervix: The ECCLIPPx Study.. REPRODUCTIVE SCIENCES, Vol. 22 (pp 331A-331A)
- Estrogen and hypoxia regulate expression of vascular endothelial growth factor and its receptors in uterine cervix of mice, which are localized in multiple cells of the tissue in mice and human. FASEB JOURNAL, Vol. 27
- Fibrinogen Attenuates sFlt-Induced Dys-Angiogenesis and Increases Vascular Adhesion Molecule Expression in Pre-Eclampsia.. REPRODUCTIVE SCIENCES, Vol. 20(S3) (pp 114A-114A)
- Monocytes of Women with Pre-Eclampsia Alter the Inflammatory Response of Human Vascular Endothelial Cells in Co-Culture. REPRODUCTIVE SCIENCES, Vol. 20(S3) (pp 114A-114A)
- The effect of factors of social exclusion on access to antenatal care and the subsequent impact on foetal outcomes. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol. 208(1) (pp S345-S346)
- Differential Expression of Tight Junction Proteins Occurs in the Pregnant Human Cervix. REPRODUCTIVE SCIENCES, Vol. 17(3) (pp 73A-73A)
- Gap Junction Protein Expression Is Down-Regulated during Pregnancy in the Human Cervix. REPRODUCTIVE SCIENCES, Vol. 17(3) (pp 73A-73A)
- Prostaglandins Induce Expression of Tight Junction but Not Gap Junction Proteins in the Pregnant Human Cervix. REPRODUCTIVE SCIENCES, Vol. 17(3) (pp 74A-74A)
- Expression Levels of Matrix Proteases and Their Inhibitors in the Serum of Pregnant Women: TIMP-2 and Relaxin Levels in 1st Trimester Are Potential Markers of Recurrent Pregnancy Loss.. REPRODUCTIVE SCIENCES, Vol. 17(3) (pp 72A-73A)
- Identifying Regulatory Gene Networks in the Myometrium Governed by NF-kappa B. REPRODUCTIVE SCIENCES, Vol. 16(3) (pp 113A-113A)
- Expression of toll-like receptor 2 in human uterine cervical epithelial cells and their cytokine responses to toll2 ligands.. REPRODUCTIVE SCIENCES, Vol. 15(2) (pp 189A-190A)
- Semi-quantitative analysis of TLR2 and TLR4 expression in the non-pregnant and pregnant cervix and the potential role of oestrogen.. REPRODUCTIVE SCIENCES, Vol. 15(2) (pp 188A-188A)
- Analysis of 22q11 deletion in foetuses with increased nuchal translucency using the Vysis TUPLE1 probe. JOURNAL OF MEDICAL GENETICS, Vol. 44 (pp S110-S110)
- Temporal expression of the membrane-bound estrogen receptor, GPR30, in lower and upper segment human myometrium.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Vol. 13(2) (pp 240A-240A)
- Subpopulations of cultured amniotic fluid cells display characteristics of pluripotent stem cells.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Vol. 13(2) (pp 163A-163A)
- Mesenchymal stem cells derived from human amniotic fluid.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Vol. 13(2) (pp 186A-186A)
- Lipopolysaccharide-induced ultra-structural changes and cytokine expression in human cervical tissue.. JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, Vol. 13(2) (pp 139A-139A)
- Placental mesenchymal dysplasia in association with Klinefelter syndrome. JOURNAL OF MEDICAL GENETICS, Vol. 41 (pp S48-S48)
- The role of prostanoids in the modulation of vascular tone in normal human pregnancy.. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 103(11) (pp 1170-1170)
- The role of nitric oxide in beta(2)-adrenoceptor-mediated vasodilatation in forearm arterial vasculature. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol. 42(5) (pp P652-P653)
- The role of nitric oxide in the modulation of vascular tone in normal pregnancy.. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol. 103(11) (pp 1169-1170)
Preprints
- Impact of a school-based nutrition educational intervention on knowledge related to iron deficiency anaemia in rural Karnataka, India: A mixed methods pre-post interventional study, Authorea, Inc..
- Ureaplasma parvum infection induces inflammatory changes in vaginal epithelial cells independent of sialidase, Research Square Platform LLC.
- The acceptability of cervical electrical impedance spectroscopy: A mixed methods study examining women’s experiences of a novel test to predict preterm birth, Research Square.
- The acceptability of cervical electrical impedance spectroscopy: A mixed methods study examining women’s experiences of a novel test to predict preterm birth, Research Square Platform LLC.
- Transcriptomic Analysis of the Human Placenta Reveals Trophoblast Dysfunction and Augmented Wnt Signalling Associated with Spontaneous Preterm Birth.
- A Socio-Ecological Approach To Understanding The Factors Influencing The Uptake Of Intermittent Preventive Treatment Of Malaria In Pregnancy (IPTp) In South Western Nigeria..
- Research group
-
Current Collaborators
- Professor (Emeritus) Brian Brown
- Dr Graham Stafford
- Dr Craig Murdoch
- Department of Medical Physics and Clinical Engineering STHFT
- Professor Adrian Porch
- Professor Zi-Qiang Lang, ACSE
- Professor Sheila MacNeil
PhD Students
- Dr Victoria Stern
- Ms Adannaya Achinanya
- Dr Brenda Narice
- Ms Megan Cavanagh
- Ms Kerry Paris
Post Doctoral Research Associates
- Dr Emmanuel Amabebe
- Dr Jill Tozer
- Dr Khundoker Akram
- Dr Shumona Salam
- Dr Bronwen Gillespie
- Ms Siobhan Gillespie
- Teaching interests
-
My main interest is postgraduate medical training and teaching.
I am Faculty of Medicine and South Yorkshire Director for Clinical Academic Training, and also Undergraduate Module Lead for Phase 3A Women´s Health, and Postgraduate Lead for the Pregnancy and Fetus Module of the MSc programme in Reproductive and Developmental Medicine.
I am Training Programme Supervisor for the Maternal and Fetal Medicine subspecialty training programme, Sheffield and serve on the South Yorkshire Foundation Training School Board, Clinical Academic Working Group, and Specialty Training Committee in Obstetrics and Gynaecology.
- Professional activities and memberships
-
I am Vice Chair of the Academic Board of the Royal College of Obstetricians and Gynaecologists and serve on several other related organs. I am Lead Clinician of the Fetal Medicine Unit, Sheffield. I served on the NICE Medical Technologies Advisory Committee (MTAC).