Dr Adrienn Angyal
Ph.D
Clinical Medicine, School of Medicine and Population Health
Postdoctoral Research Associate
A.Angyal@sheffield.ac.uk
+44 114 215 9579
+44 114 215 9579
The Medical School
Full contact details
Dr Adrienn Angyal
Clinical Medicine, School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX
Clinical Medicine, School of Medicine and Population Health
The Medical School
Beech Hill Road
Sheffield
S10 2RX
- Qualifications
-
- B.Sc. in Biology.
- M.Sc. in Molecular Immunology.
- Ph.D. in Molecular Immunology.
- Research interests
-
I am interested in anti-viral T cell responses, particularly in characterising the phenotype of the antigen-specific memory T cell populations that are generated in individuals upon natural viral infection with SARS-CoV-2 and/or as a consequence of the vaccination schedule.
- Publications
-
Show: Featured publications All publications
Featured publications
Journal articles
- Characterising within-hospital SARS-CoV-2 transmission events using epidemiological and viral genomic data across two pandemic waves. Nature Communications, 13(1). View this article in WRRO
- T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study. The Lancet Microbe, 3(1), e21-e31. View this article in WRRO
- The impact of viral mutations on recognition by SARS-CoV-2 specific T cells. iScience, 24(11). View this article in WRRO
- Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine. Cell, 184(23), 5699-5714.e11. View this article in WRRO
- The D614G mutations in the SARS-CoV-2 spike protein: Implications for viral infectivity, disease severity and vaccine design. Biochemical and Biophysical Research Communications, 538, 104-107.
- Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus. Cell, 182(4), 812-827.e19. View this article in WRRO
Preprints
- T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses, Cold Spring Harbor Laboratory.
All publications
Journal articles
- Publisher Correction: Characterising within-hospital SARS-CoV-2 transmission events using epidemiological and viral genomic data across two pandemic waves. Nature Communications, 13(1).
- Characterising within-hospital SARS-CoV-2 transmission events using epidemiological and viral genomic data across two pandemic waves. Nature Communications, 13(1). View this article in WRRO
- T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study. The Lancet Microbe, 3(1), e21-e31. View this article in WRRO
- The impact of viral mutations on recognition by SARS-CoV-2 specific T cells. iScience, 24(11). View this article in WRRO
- Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine. Cell, 184(23), 5699-5714.e11. View this article in WRRO
- Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature, 593(7858), 266-269. View this article in WRRO
- The impact of viral mutations on recognition by SARS-CoV-2 specific T-cells.
- T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses. Nature Communications, 12(1). View this article in WRRO
- Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data. Genome Research, 31(4), 645-658. View this article in WRRO
- The D614G mutations in the SARS-CoV-2 spike protein: Implications for viral infectivity, disease severity and vaccine design. Biochemical and Biophysical Research Communications, 538, 104-107.
- Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus. Cell, 182(4), 812-827.e19. View this article in WRRO
- An integrated national scale SARS-CoV-2 genomic surveillance network. The Lancet Microbe, 1(3), e99-e100. View this article in WRRO
- periscope: sub-genomic RNA identification in SARS-CoV-2 Genomic Sequencing Data. View this article in WRRO
- Pneumolysin is responsible for differential gene expression and modifications in the epigenetic landscape of primary monocyte derived macrophages.
- Myeloid tribbles 1 induces early atherosclerosis via enhanced foam cell expansion. Science Advances, 5(10). View this article in WRRO
- TMEM203 is a binding partner and regulator of STING-mediated inflammatory signaling in macrophages. Proceedings of the National Academy of Sciences. View this article in WRRO
- Hypoxia upregulates neutrophil degranulation and potential for tissue injury. Thorax, 71(11), 1030-1038. View this article in WRRO
- Competition between members of the tribbles pseudokinase protein family shapes their interactions with mitogen activated protein kinase pathways. Scientific Reports, 6. View this article in WRRO
- T-bet is a new synergistic meeting point for the BCR and TLR9 signaling cascades. European Journal of Immunology, 44(3), 887-893.
- Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosis.. Biology (Basel), 1(1), 43-57. View this article in WRRO
- The tribbles gene family and lipoprotein metabolism.. Curr Opin Lipidol, 23(2), 122-126.
- Tribbles-2 is a novel regulator of inflammatory activation of monocytes.. Int Immunol, 20(12), 1543-1550. View this article in WRRO
- Pneumolysin Is Responsible for Differential Gene Expression and Modifications in the Epigenetic Landscape of Primary Monocyte Derived Macrophages. Frontiers in Immunology, 12.
- T-Cell and Antibody Responses to First BNT162b2 Vaccine Dose in Previously SARS-CoV-2-Infected and Infection-Naive UK Healthcare Workers: A Multicentre, Prospective, Observational Cohort Study. SSRN Electronic Journal.
Chapters
- Tribbles, Encyclopedia of Signaling Molecules (pp. 5690-5697). Springer International Publishing
Conference proceedings papers
- Myeloid TRIB1 Controls Metabolic Tissue Resident Macrophage Phenotype Associated with Immuno-Metabolic Diseases. CARDIOVASCULAR DRUGS AND THERAPY, Vol. 33(2) (pp 271-271)
- P14 MYELOID TRIB1 PROMOTES EXPERIMENTAL ATHEROSCLEROSIS. Cardiovascular Research, Vol. 114(suppl_2) (pp S4-S4)
- Myeloid Tribbles 1 Regulates Experimental Atherosclerosis. Atherosclerosis Supplements, Vol. 32 (pp 11-11)
- 123 Myeloid TRIB1 controls experimental atherosclerosis. Basic Science
- 157 Myeloid expression of trib1 regulates the polarisation state of tissue resident macrophages that has consequences on plasma lipid and metabolic homeostasis. Heart, Vol. 103(Suppl 5) (pp A113.2-A113)
- Does myeloid expression of TRIB1 regulate plasma lipid levels?. Atherosclerosis, Vol. 241(1) (pp e34-e34)
- 223 MIRNA202 is a Novel Regulator of Tribbles-1 Expression. Heart, Vol. 101(Suppl 4) (pp A121.2-A121)
- 186 Assessment of Plaque Macrophage Phenotypein situby Multicolour Fluorescence Microscopy. Heart, Vol. 101(Suppl 4) (pp A104.2-A105)
- A NOVEL ROLE FOR THE GAS3/PMP22 FAMILY MEMBER EMP2 IN THE REGULATION OF INFLAMMATION. HEART, Vol. 99
- TRIBBLES-1 CONTRIBUTES TO MONOCYTE MIGRATION IN EXPERIMENTAL PERITONITIS. HEART, Vol. 99 (pp A126-A126)
- THE ROLE OF TRIBBLES 2 IN PI3K CASCADE REGULATION AND AKT/PKB ANTI-APOPTOTIC SIGNALLING CASCADE. HEART, Vol. 95(22)
Preprints
- Evolution of long-term hybrid immunity in healthcare workers after different COVID-19 vaccination regimens: a longitudinal observational cohort study, Cold Spring Harbor Laboratory.
- T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses, Cold Spring Harbor Laboratory.
- Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion, Cold Spring Harbor Laboratory.
- The Impact of Viral Mutations on Recognition by SARS-CoV-2 Specific T-Cells.
- T-Cell and Antibody Responses to First BNT162b2 Vaccine Dose in Previously SARS-CoV-2-Infected and Infection-Naive UK Healthcare Workers: A Multicentre, Prospective, Observational Cohort Study.
- Teaching interests
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I am involved in teaching immunology at the Molecular medicine M.Sc. course.
- Awarded greats:
COG-UK supplementary funding to 166547 (Research Project Fund)