Chloe Thomas

All publications

Journal articles

• Thomas C, Heathcote L, Sun Y, Callister MEJ, Kitt J, Rossi SH, Shinkins B, Usher-Smith JA, Whyte S & Stewart GD (2025) Cost-effectiveness of one-off upper abdominal CT screening as an add-on to lung cancer screening in England. British Journal of Cancer. View this article in WRRO
• Mensah JP, Thomas C, Akparibo R & Brennan A (2025) Public health economic modelling in evaluations of salt and/or alcohol policies: a systematic scoping review. BMC Public Health, 25(1). View this article in WRRO
• Chanakira EZ, Thomas CV, Balen J & Mandrik O (2024) A systematic review of public health interventions to address breast cancer inequalities in low- and middle-income countries. Systematic Reviews, 13(1). View this article in WRRO
• Dennison RA, Clune RJ, Morris S, Thomas C & Usher‐Smith JA (2024) Understanding the Preferences and Considerations of the Public Towards Risk‐Stratified Screening for Colorectal Cancer: Insights From Think‐Aloud Interviews Based on a Discrete Choice Experiment. Health Expectations, 27(4).
• Mandrik O, Thomas C & Chilcott J (2024) Development of the Microsimulation Model in Cancers of Bladder and Kidney (MiMiC-BlaKy). HEDS Discussion Paper Series(24.03). View this article in WRRO
• Lally P, Kennedy F, Smith S, Beeken RJ, Buck C, Thomas C, Counsell N, Wyld L, Martin C, Williams S , Roberts A et al (2024) The feasibility and acceptability of an app-based intervention with brief behavioural support (APPROACH) to promote brisk walking in people diagnosed with breast, prostate and colorectal cancer in the UK. Cancer Medicine, 13(6). View this article in WRRO
• Bates S, Breeze P, Thomas C, Jackson C, Church O & Brennan A (2024) Cross-model validation of public health microsimulation models; comparing two models on estimated effects of a weight management intervention. BMC Public Health, 24. View this article in WRRO
• Mensah J, Thomas C, Akparibo R & Brennan A (2023) SA18 Public Health Economic Modelling in Evaluations of Salt and Alcohol Policies: A Scoping Review. Value in Health, 26(12), S544-S544.
• Dennison RA, Thomas CV, Morris S & Usher-Smith JA (2023) A discrete choice experiment to understand public preferences and priorities for risk-stratified bowel cancer screening programmes in the UK. Preventive Medicine, 177(107786). View this article in WRRO
• Scragg J, Morris E, Wane S, Noreik M, Jerome D, Yu L-M, Galal U, Dyson P, Tan GD, Fox R , Breeze P et al (2023) Dietary Approaches to the Management Of type 2 Diabetes (DIAMOND) in primary care: A protocol for a cluster randomised trial. Contemporary Clinical Trials, 129, 107199-107199.
• Ahern AL, Breeze P, Fusco F, Sharp SJ, Islam N, Wheeler GM, Hill AJ, Hughes CA, Duschinsky R, Thomas C , Bates S et al (2022) Effectiveness and cost-effectiveness of referral to a commercial open group behavioural weight management programme in adults with overweight and obesity: 5-year follow-up of the WRAP randomised controlled trial. The Lancet Public Health, 7(10), e866-e875.
• Thomas C, Breeze P, Cummins S, Cornelsen L, Yau A & Brennan A (2022) The health, cost and equity impacts of restrictions on the advertisement of high fat, salt and sugar products across the transport for London network: a health economic modelling study. International Journal of Behavioral Nutrition and Physical Activity, 19. View this article in WRRO
• Thomas C, Mandrik O & Whyte S (2022) Modelling cost-effective strategies for minimising socioeconomic inequalities in colorectal cancer screening outcomes in England. Preventive Medicine, 162. View this article in WRRO
• Dennison RA, Boscott RA, Thomas R, Griffin SJ, Harrison H, John SD, Moorthie SA, Morris S, Rossi SH, Stewart GD , Thomas CV et al (2022) A community jury study exploring the public acceptability of using risk stratification to determine eligibility for cancer screening. Health Expectations.
• Mandrik O, Chilcott J & Thomas C (2022) Modelling the impact of the coronavirus pandemic on bowel cancer screening outcomes in England: a decision analysis to prepare for future screening disruption. Preventive Medicine, 160. View this article in WRRO
• Smith R, Thomas C, Squires H & Goyder E (2022) A comparison of the World Health Organisation's HEAT model results using a non-linear physical activity dose response function with results from the existing tool. Wellcome Open Research, 7. View this article in WRRO
• Lally P, Miller N, Roberts A, Beeken RJ, Greenfield DM, Potts HWW, Counsell N, Latimer N, Thomas C, Smith L , Gath J et al (2022) An app with brief behavioural support to promote physical activity after a cancer diagnosis (APPROACH) : study protocol for a pilot randomised controlled trial. Pilot and Feasibility Studies, 8(1), 74-74. View this article in WRRO
• Bates SE, Thomas C, Islam N, Ahern AL, Breeze P, Griffin S & Brennan A (2022) Using health economic modelling to inform the design and development of an intervention : estimating the justifiable cost of weight loss maintenance in the UK. BMC Public Health, 22(1). View this article in WRRO
• Richards R, Jones RA, Whittle F, Hughes CA, Hill AJ, Lawlor ER, Bostock J, Bates S, Breeze PR, Brennan A , Thomas CV et al (2022) Development of a Web-Based, Guided Self-help, Acceptance and Commitment Therapy-Based Intervention for Weight Loss Maintenance: Evidence-, Theory-, and Person-Based Approach.. JMIR Form Res, 6(1), e31801.
• Smith R, Thomas C, Squires H & Goyder E (2022) A comparison of the World Health Organisation's HEAT model results using a non-linear physical activity dose response function with results from the existing tool. Wellcome Open Research, 7(2022). View this article in WRRO
• Whyte S, Thomas C, Chilcott J & Kearns B (2022) Optimizing the design of a repeated fecal immunochemical test bowel cancer screening programme with a limited endoscopy capacity from a health economic perspective. Value in Health, 25(6), 954-964. View this article in WRRO
• Thomas C, Mandrik O, Saunders CL, Thompson D, Whyte S, Griffin S & Usher-Smith JA (2021) The costs and benefits of risk-stratification for colorectal cancer screening based on phenotypic and genetic risk: a health economic analysis. Cancer Prevention Research, 14(8), 811-822. View this article in WRRO
• Smith R, Thomas C, Squires H, Götschi T, Kahlmeier S & Goyder E (2021) The price of precision: trade-offs between usability and validity in the World Health Organization Health Economic Assessment Tool for walking and cycling.. Public Health, 194, 263-269.
• Rubin G, Walter FM, Emery J, Hamilton W, Hoare Z, Howse J, Nixon C, Srivastava T, Thomas C, Ukoumunne OC , Usher-Smith JA et al (2021) Electronic clinical decision support tool for assessing stomach symptoms in primary care (ECASS): a feasibility study. BMJ Open, 11(3).
• Breeze P, Thomas C, Thokala P, LaFortune L, Brayne C & Brennan A (2020) The impact of including costs and outcomes of dementia in a health economic model to evaluate lifestyle interventions to prevent diabetes and cardiovascular disease. Medical Decision Making. View this article in WRRO
• Thomas C, Whyte S, Kearns B & Chilcott JB (2019) External Validation of a Colorectal Cancer Model Against Screening Trial Long-Term Follow-Up Data. Value in Health, 22(10), 1154-1161. View this article in WRRO
• Thomas C, Sadler S, Breeze P, Squires H, Gillett M & Brennan A (2017) Assessing the potential return on investment of the proposed UK NHS diabetes prevention programme in different population subgroups: an economic evaluation. BMJ Open, 7. View this article in WRRO
• Breeze PR, Thomas C, Squires H, Brennan A, Greaves C, Diggle P, Brunner E, Tabak A, Preston L & Chilcott J (2017) Cost‐effectiveness of population‐based, community, workplace and individual policies for diabetes prevention in the UK. Diabetic Medicine, 34(8), 1136-1144. View this article in WRRO
• Dunkley A, Tyrer F, Spong R, Gray L, Gillett MJ, Doherty Y, Martin-Stacey L, Patel N, Yates T, Bhaumik S , Chalk T et al (2017) Screening for glucose intolerance and development of a lifestyle education programme for prevention of type 2 diabetes in a population with intellectual disabilities: the STOP Diabetes research project. Programme Grants for Applied Research, 5(11). View this article in WRRO
• Breeze PR, Thomas C, Squires H, Brennan A, Greaves C, Diggle PJ, Brunner E, Tabak A, Preston L & Chilcott J (2017) The impact of Type 2 diabetes prevention programmes based on risk‐identification and lifestyle intervention intensity strategies: a cost‐effectiveness analysis. Diabetic Medicine, 34(5), 632-640. View this article in WRRO
• Angus CR, Thomas C, Anderson P, Meier P & Brennan A (2017) Estimating the cost-effectiveness of brief interventions for heavy drinking in primary health care across Europe. European Journal of Public Health, 27(2), 345-351. View this article in WRRO
• Thomas C, Breeze P, Strong M, Brennan A, Norman P, Cameron D & Epton T (2016) The cost-effectiveness of an updated theory-based online health behavior intervention for new university students: U@Uni2. Journal of Public Health & Epidemiology, 8(10), 191-203. View this article in WRRO
• (2016) Retracted:Impact of Type 2 diabetes prevention programmes based on risk identification and lifestyle intervention intensity strategies: a cost-effectiveness analysis. Diabetic Medicine, 33(8), 1155-1163.
• Cameron D, Norman P, Epton T, Sheeran P, Harris PR, Webb TL, Julious SA, Brennan A, Thomas C, Petroczi A , Naughton D et al (2015) A theory-based online health behaviour intervention for new university students (U@Uni:LifeGuide): Results from a repeat randomized controlled trial. Trials, 16. View this article in WRRO
• Kruger J, Brennan A, Strong M, Thomas C, Norman P & Epton T (2014) The cost-effectiveness of a theory-based online health behaviour intervention for new university students: an economic evaluation. BMC Public Health, 14(1). View this article in WRRO
• Thomas C & Strutt D (2014) Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster.. Dev Biol, 385(1), 107-121. View this article in WRRO
• Brittle A, Thomas C & Strutt D (2012) Planar Polarity Specification through Asymmetric Subcellular Localization of Fat and Dachsous. Current Biology.
• Thomas C & Strutt D (2011) The roles of the cadherins Fat and Dachsous in planar polarity specification in Drosophila. Developmental Dynamics, 192(4).
• Thomas C, Rousset R & Noselli S (2009) JNK signalling influences intracellular trafficking during Drosophila morphogenesis through regulation of the novel target gene Rab30. Developmental Biology, 331(2), 250-260.
• Nakano Y, Nystedt S, Shivdasani AA, Strutt H, Thomas C & Ingham PW (2004) Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila.. Mech Dev, 121(6), 507-518.
• Thomas C & Ingham PW (2003) Hedgehog signaling in the Drosophila eye and head: an analysis of the effects of different patched trans-heterozygotes.. Genetics, 165(4), 1915-1928.
• Strutt H, Thomas C, Nakano Y, Stark D, Neave B, Taylor AM & Ingham PW (2001) Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation.. Curr Biol, 11(8), 608-613.
• Strutt H, Thomas C, Nakano Y, Stark D, Neave B, Taylor AM & Ingham PW (2001) Erratum: Mutations in the sterol sensing domain of patched suggest a role for vesicular trafficking in Smoothened regulation (current biology (2001) 11:8 (608-613)). Current Biology, 11(14), 1153.
• Thomas C, Mandrik O, Chilcott J, Crooks C, Humes D, Hamilton W & Rees C () Cost-effectiveness of FIT and a FIT-based model to optimise symptomatic diagnosis of colorectal cancer: health economic modelling for the COLOFIT project. BMJ Public Health. View this article in WRRO
• Breeze P, Pidd K, Pollard D, Ren S, Bates S, Thomas C, Ahern A, Griffin S & Brennan A () Assessing the value for money, from a policy maker perspective, of 24 randomised controlled trial designs for an online weight maintenance guided self-help intervention: an expected value of sample information analysis. International Journal of Obesity.
• Mandrik O, Thomas C, Akpan E, Catto JWF & Chilcott J () Home Urine Dipstick Screening for Bladder and Kidney Cancer in High-Risk Populations in England: A Microsimulation Study of Long-Term Impact and Cost-Effectiveness. PharmacoEconomics.
• Taylor LC, Dennison RA, Griffin SJ, John SD, Lansdorp-Vogelaar I, Thomas CV, Thomas R & Usher-Smith JA () Implementation of risk stratification within bowel cancer screening: a community jury study exploring public acceptability and communication needs. BMC Public Health, 23(1).
• Breeze P, Gray LA, Thomas C, Bates SE & Brennan A () Estimating the impact of changes in weight and BMI on EQ-5D-3L: a longitudinal analysis of a behavioural group-based weight loss intervention. Quality of Life Research.
• Tew M, Willis M, Asseburg C, Bennett H, Brennan A, Feenstra T, Gahn J, Gray A, Heathcote L, Herman WH , Isaman D et al () Exploring Structural Uncertainty and Impact of Health State Utility Values on Lifetime Outcomes in Diabetes Economic Simulation Models: Findings from the Ninth Mount Hood Diabetes Quality-of-Life Challenge. Medical Decision Making, 0272989X2110654-0272989X2110654.
• Thomas C, Mandrik O, Whyte S, Saunders C, Griffin S & Usher-Smith J () Should colorectal cancer screening start at different ages for men and women? Cost-effectiveness analysis for a resource constrained service. Cancer Reports.
• Thomas C, Brennan A, Squires H, Brenner G, Bagguley D, Woods H, Gillett M, Leaviss J, Clowes M, Heathcote L , Cooper K et al () What are the cost-savings and health benefits of improving detection and management for six high cardiovascular risk conditions in England? An economic evaluation. BMJ Open. View this article in WRRO
• Kearns B, Cooper K, Cantrell A & Thomas C () Schizophrenia treatment with second-generation antipsychotics: a multi-country comparison of the costs of cardiovascular and metabolic adverse events and weight gain. Neuropsychiatric Disease and Treatment.
• Mandrik O, Thomas C, Whyte S & Chilcott J () CALIBRATING NATURAL HISTORY OF CANCER MODELS IN THE PRESENCE OF DATA INCOMPATIBILITY; PROBLEMS AND SOLUTIONS. PharmacoEconomics.

Conference proceedings papers

• Mensah J, Thomas C, Akparibo R & Brennan A (2023) PUBLIC HEALTH ECONOMIC MODELLING IN EVALUATIONS OF SALT AND ALCOHOL POLICIES: A SCOPING REVIEW. VALUE IN HEALTH, Vol. 26(12) (pp S544-S544)
• Kennedy F, Miller N, Roberts A, Beeken RJ, Greenfield D, Potts HWW, Counsell N, Latimer N, Thomas C, Smith L , Gath J et al (2022) Promoting physical activity via a smartphone application in people living with breast, prostate or colorectal cancer: study protocol for a randomised pilot trial (APPROACH). PSYCHO-ONCOLOGY, Vol. 31 (pp 20-20)
• Thomas C, Watson P, Squires H, Chilcott J & Brennan A (2014) Validation of the SPHR Diabetes Prevention Model. Value in Health, Vol. 17(7) (pp A556-A556)
• Thomas C, Watson P, Greaves C, Squires H, Chilcott J & Brennan A (2014) Layering Interventions for Type-2 Diabetes Prevention Using The Sphr Diabetes Model. Value in Health, Vol. 17(7) (pp A347-A347)

Reports

• Srivastava T, Chambers D, Thomas C & Whyte S (2019) ECASS health economic feasibility study View this article in WRRO
• Whyte S, Thomas C, Kearns B, Webster M & Chilcott J (2017) Optimising Bowel Cancer Screening Phase 1: Optimising the cost effectiveness of repeated FIT screening and screening strategies combining bowel scope and FIT screening View this article in WRRO

Other

• Thomas C, Mandrik O, Saunders CL, Thompson D, Whyte S, Griffin S & Usher-Smith JA (2023) Supplementary Data from The Costs and Benefits of Risk Stratification for Colorectal Cancer Screening Based On Phenotypic and Genetic Risk: A Health Economic Analysis.
• Thomas C, Mandrik O, Saunders CL, Thompson D, Whyte S, Griffin S & Usher-Smith JA (2023) Supplementary Data from The Costs and Benefits of Risk Stratification for Colorectal Cancer Screening Based On Phenotypic and Genetic Risk: A Health Economic Analysis.
• Thomas C, Mandrik O, Saunders CL, Thompson D, Whyte S, Griffin S & Usher-Smith JA (2023) Data from The Costs and Benefits of Risk Stratification for Colorectal Cancer Screening Based On Phenotypic and Genetic Risk: A Health Economic Analysis.
• Thomas C, Mandrik O, Saunders CL, Thompson D, Whyte S, Griffin S & Usher-Smith JA (2023) Data from The Costs and Benefits of Risk Stratification for Colorectal Cancer Screening Based On Phenotypic and Genetic Risk: A Health Economic Analysis.

Preprints

• Mandrik O, Thomas C, Strong M & Whyte S (2021) Calibration and Validation of the Microsimulation Model in Cancer of the Bowel (MiMiC-Bowel), an Individual Patient Simulation Model for Investigation of the Cost-effectiveness of Personalised Screening and Surveillance Strategies.. View this article in WRRO
• Scragg J, Morris E, Wane S, Noreik M, Jerome D, Yu L-M, Galal U, Dyson P, Tan GD, Fox R , Breeze P et al () Dietary Approaches to the Management of Type 2 Diabetes (DIAMOND) in Primary Care: A Protocol for a Cluster Randomised Trial.
• Lally P, Miller N, Roberts A, Beeken RJ, Greenfield DM, Potts HWW, Counsell N, Latimer N, Thomas C, Smith L , Gath J et al () An App With Brief Behavioural Support to Promote Physical Activity After a Cancer Diagnosis (APPROACH): Study Protocol for a Pilot Randomised Controlled Trial, Research Square Platform LLC.
• Richards R, Jones RA, Whittle F, Hughes CA, Hill AJ, Lawlor ER, Bostock J, Bates S, Breeze PR, Brennan A , Thomas CV et al () Development of a Web-Based, Guided Self-help, Acceptance and Commitment Therapy–Based Intervention for Weight Loss Maintenance: Evidence-, Theory-, and Person-Based Approach (Preprint), JMIR Publications Inc..