Dr Lesley Uttley
BSc, PhD (Psychology)
Population Health, School of Medicine and Population Health
Senior Research Fellow
+44 114 222 0782
Full contact details
Population Health, School of Medicine and Population Health
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
- Profile
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I am a Senior Research Fellow and Career Development Award (2020-2024) and Transition Support Award (2025-2026) holder for investigating human influences in systematic reviews and meta-analyses, funded by the UKRI Medical Research Council (MRC). I obtained my BSc and PhD in Psychology at the University of Sheffield. I joined SMPH as a systematic reviewer in January 2011 for the evidence review group, SCHARR-TAG, leading technology assessments until 2019 for interventions across a range of specialities including mental health, oncology and diagnostics. I design, lead and conduct systematic reviews including a living review of the problems with systematic reviews. I am interested in how the people, or the systematic review team, can potentially influence the output of apparently objective research projects.
As well as leading Systematic Reviewlution I am also working on the ESRC funded Behavioural Research UK project (2023-2027) and the NIHR funded Sheffield Biomedical Research Centre (2024-2026).
I was invited to be an Editorial Board Member of the Journal of Clinical Epidemiology in October 2024 following my role as Guest Editor for the journal on the Special Issue "Methodological Aspects of Research Integrity and Research Culture."
- Research interests
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- Research integrity and research culture
- Positive and negative human influences in research
- Methodology of systematic reviews
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- The Problems with Systematic Reviews: A Living Systematic Review. Journal of Clinical Epidemiology.
- Invited commentary - WHO classification of tumors : how should tumours be classified? Expert consensus, systematic reviews or both?. International Journal of Cancer. View this article in WRRO
- Creutzfeldt-Jakob disease: a systematic review of global incidence, prevalence, infectivity, and incubation. The Lancet Infectious Diseases, 20(1), e2-e10. View this article in WRRO
- A review of quality of life themes in Duchenne muscular dystrophy for patients and carers.. Health and Quality of Life Outcomes, 16. View this article in WRRO
- Tofacitinib for Treating Rheumatoid Arthritis After the Failure of Disease-Modifying Anti-rheumatic Drugs: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.. Pharmacoeconomics, 36(9), 1063-1072. View this article in WRRO
- The influence of the team in conducting a systematic review.. Systematic Reviews, 6. View this article in WRRO
- Degarelix for Treating Advanced Hormone-Dependent Prostate Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 35(7), 717-726. View this article in WRRO
- Building the Evidence Base of Blood-Based Biomarkers for Early Detection of Cancer: A Rapid Systematic Mapping Review. EBioMedicine. View this article in WRRO
- Systematic review of the dry powder inhalers colistimethate sodium and tobramycin in cystic fibrosis.. Eur Respir Rev, 22(130), 476-486.
- Aripiprazole for the treatment and prevention of acute manic and mixed episodes in bipolar I disorder in children and adolescents: a NICE single technology appraisal.. Pharmacoeconomics, 31(11), 981-990.
- Minimally invasive oesophagectomy versus open surgery: is there an advantage?. Surg Endosc, 27(3), 724-731.
- Systematic review and economic modelling of the clinical effectiveness and cost-effectiveness of art therapy among people with non-psychotic mental health disorders. Health Technology Assessment, 19(18), 1-120. View this article in WRRO
All publications
Journal articles
- Research Culture’s Role in Contributing to Research Waste: Lessons from Systematic Reviewlution. Exchanges: The Interdisciplinary Research Journal, 11(3), 114-125.
- The Problems with Systematic Reviews: A Living Systematic Review. Journal of Clinical Epidemiology.
- Living health technology assessment: issues, challenges and opportunities. PharmacoEconomics, 41(3), 227-237.
- Housing with care for older people: a scoping review using the CASP assessment tool to inform optimal design. HERD: Health Environments Research & Design Journal, 15(4), 299-322.
- Clonality, mutation and kaposi sarcoma: a systematic review. Cancers, 14(5).
- A review and analysis of the components of potentially effective perinatal mental health interventions for infant development and mother-infant relationship outcomes. Development and Psychopathology.
- Invited commentary - WHO classification of tumors : how should tumours be classified? Expert consensus, systematic reviews or both?. International Journal of Cancer. View this article in WRRO
- Interventions to reduce the risk of surgically transmitted Creutzfeldt–Jakob disease: a cost-effective modelling review. Health Technology Assessment, 24(11), 1-150. View this article in WRRO
- Creutzfeldt-Jakob disease: a systematic review of global incidence, prevalence, infectivity, and incubation. The Lancet Infectious Diseases, 20(1), e2-e10. View this article in WRRO
- Sex Categorization of Faces: The Effects of Age and Experience. i-Perception, 10(1). View this article in WRRO
- A review of quality of life themes in Duchenne muscular dystrophy for patients and carers.. Health and Quality of Life Outcomes, 16. View this article in WRRO
- Routine thyroglobulin, neck ultrasound and physical examination in the routine follow up of patients with differentiated thyroid cancer—Where is the evidence?. Endocrine, 62(1), 26-33. View this article in WRRO
- Tofacitinib for Treating Rheumatoid Arthritis After the Failure of Disease-Modifying Anti-rheumatic Drugs: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.. Pharmacoeconomics, 36(9), 1063-1072. View this article in WRRO
- The evidence base for circulating tumour DNA blood-based biomarkers for the early detection of cancer: a systematic mapping review. BMC Cancer, 17, 697-697. View this article in WRRO
- The influence of the team in conducting a systematic review.. Systematic Reviews, 6. View this article in WRRO
- Degarelix for Treating Advanced Hormone-Dependent Prostate Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 35(7), 717-726. View this article in WRRO
- A qualitative systematic review of service user and service provider perspectives on the acceptability, relative benefits, and potential harms of art therapy for people with non‐psychotic mental health disorders. Psychology and Psychotherapy: Theory, Research and Practice, 90(1), 25-43. View this article in WRRO
- Systematic Review of Trends in the Incidence Rates of Thyroid Cancer.. Thyroid, 26(11), 1541-1552. View this article in WRRO
- Building the Evidence Base of Blood-Based Biomarkers for Early Detection of Cancer: A Rapid Systematic Mapping Review. EBioMedicine. View this article in WRRO
- Sepsis: the LightCycler SeptiFast Test MGRADE®, SepsiTest™ and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi - a systematic review and economic evaluation.. Health Technology Assessment, 20(46), 1-246. View this article in WRRO
- The clinical and cost effectiveness of group art therapy for people with non-psychotic mental health disorders: a systematic review and cost-effectiveness analysis. BMC Psychiatry, 15. View this article in WRRO
- Psychotherapeutic benefits of compassion-focused therapy: an early systematic review. Psychological Medicine, 45(05), 927-945. View this article in WRRO
- Erratum to: The clinical and cost effectiveness of group art therapy for people with non-psychotic mental health disorders: a systematic review and cost-effectiveness analysis. BMC Psychiatry, 15(1). View this article in WRRO
- Effectiveness of Preventative and Other Surgical Measures on Hypocalcemia Following Bilateral Thyroid Surgery: A Systematic Review and Meta-Analysis. Thyroid, 25(1), 95-106.
- Reprint of: Effectiveness of preventative and other surgical measures on hypocalcaemia following bilateral thyroid surgery: A systematic review and meta-analysis. European Journal of Surgical Oncology (EJSO), 40(12), 1802-1802.
- Dry powder inhalers in cystic fibrosis. Current Opinion in Pulmonary Medicine, 20(6), 607-612.
- Effectiveness of preventative and other surgical measures on hypocalcaemia following bilateral thyroid surgery: A systematic review and meta-analysis. European Journal of Surgical Oncology (EJSO), 40, S5-S6.
- Female face preference in 4-month-olds: The importance of hairline. Infant Behavior and Development, 37(4), 676-681. View this article in WRRO
- Authors' reply: Systematic review and meta-analysis of predictors of post-thyroidectomy hypocalcaemia (Br J Surg 2014; 101: 307-320).. Br J Surg, 101(7), 883-884.
- The Cost Effectiveness of Dry Powder Antibiotics for the Treatment of Pseudomonas aeruginosa in Patients with Cystic Fibrosis. PHARMACOECONOMICS, 32(2), 159-172.
- Systematic review and meta-analysis of predictors of post-thyroidectomy hypocalcaemia.. Br J Surg, 101(4), 307-320.
- Systematic review of the dry powder inhalers colistimethate sodium and tobramycin in cystic fibrosis.. Eur Respir Rev, 22(130), 476-486.
- Colistimethate sodium powder and tobramycin powder for inhalation for the treatment of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis: systematic review and economic model.. Health Technol Assess, 17(56), v-181.
- Minimally invasive esophagectomy versus open surgery: is there an advantage?. Surgical Endoscopy, 27(11), 4401-4402.
- Aripiprazole for the treatment and prevention of acute manic and mixed episodes in bipolar I disorder in children and adolescents: a NICE single technology appraisal.. Pharmacoeconomics, 31(11), 981-990.
- Six-month-old infants match other-race faces with a non-native language.. International Journal of Behavioural Development..
- Minimally invasive oesophagectomy versus open surgery: is there an advantage?. Surg Endosc, 27(3), 724-731.
- Infant preference for female faces occurs for same-but not other-race faces. J NEUROPSYCHOL, 2, 15-26.
- Systematic review and economic modelling of the clinical effectiveness and cost-effectiveness of art therapy among people with non-psychotic mental health disorders. Health Technology Assessment, 19(18), 1-120. View this article in WRRO
- Systematic review and modelling of the cost-effectiveness of cardiac magnetic resonance imaging compared with current existing testing pathways in ischaemic cardiomyopathy. Health Technology Assessment, 18(59), 1-120.
Chapters
- Surgery versus surveillance for asymptomatic (mild) primary hyperparathyroidism in adults 50 years or older John Wiley & Sons, Ltd
Conference proceedings papers
- Understanding bias, conflicts of interest and researcher allegiance in systematic reviews. BMJ Evidence-Based Medicine, Vol. 24(Suppl 1) (pp a33-a34). Oxford, UK, 15 July 2019 - 17 July 2019. View this article in WRRO
- Effectiveness of routine thyroglobulin, ultrasound and physical examination in follow-up of patients with differentiated thyroid cancer – A systematic review. European Journal of Surgical Oncology, Vol. 43(12) (pp 2396-2397)
- The Cost Effectiveness of Group Art Therapy for Patients with Non-Psychotic Mental Health Disorders in England And Wales. Value in Health, Vol. 17(7) (pp A458-A459)
- The Cost-Effectiveness of Dry Powder Antibiotics for the Treatment of Pseudomonas Aeruginosa in Patients with Cystic Fibrosis. Value in Health, Vol. 16(7) (pp A372-A372)
- SYSTEMATIC REVIEW OF COLISTIMETHATE SODIUM DRY POWDER AND TOBRAMYCIN DRY POWDER ANTIBIOTICS FOR PSEUDOMONAS AERUGINOSA LUNG INFECTION IN CYSTIC FIBROSIS. VALUE IN HEALTH, Vol. 16(7) (pp A367-A367)
- SHOULD THERE BE AN OPTION TO "UNREFER" NICE SINGLE TECHNOLOGY APPRAISALS: CASE STUDY OF ARIPIPRAZOLE FOR BIPOLAR I DISORDER IN ADOLESCENTS. VALUE IN HEALTH, Vol. 16(7) (pp A615-A616)
Reports
Posters
- Teaching activities
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- Supervisor to PhD students on systematic review topics
- Supervisor to masters student dissertation involving systematic reviews
- Deliver lectures and workshops in systematic review and meta-analysis
- Professional activities and memberships
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Internal
- EDI Fellow for NIHR Sheffield BRC
- UoS Open Research Champion
- Co-chair for ScHARR Systematic Reviewers academic development group
External
- Invited Editorial Board Member for The Journal of Clinical Epidemiology
- Invited Visiting Scientist to the World Health Organisation (WHO) International Agency for Research on Cancer (IARC)
- Member of the ESRC funded Behavioural Research UK Leadership Hub