Professor Simon Heller

All publications

Journal articles

• Holmes-Truscott E, Schipp J, Cooke DD, Hendrieckx C, Coates EJ, Heller SR & Speight J (2024) Perceptions of adults with type 1 diabetes toward diabetes-specific quality of life measures: a survey-based qualitative exploration. Health and Quality of Life Outcomes, 22(1), 70.
• Divilly P, Martine-Edith G, Zaremba N, Søholm U, Mahmoudi Z, Cigler M, Ali N, Abbink EJ, Brøsen J, de Galan B , Pedersen-Bjergaard U et al (2024) Relationship Between Sensor-Detected Hypoglycemia and Patient-Reported Hypoglycemia in People With Type 1 and Insulin-Treated Type 2 Diabetes: The Hypo-METRICS Study. Diabetes Care, 47(10), 1769-1777.
• Johansen RF, Caunt S, Heller S, Sander SE, Søndergaard E, Molsted S & Kristensen PL (2024) Factors Influencing Physical Activity level in Adults with Type 1 Diabetes: A Cross-Sectional Study. Canadian Journal of Diabetes.
• HELLER SR, GOPALAKRISHNAN UNNIKRISHNAN A, AKKUS O, LINJAWI S & SHAH MJ (2024) 833-P: Understanding Attitudes about Basal Insulin—Insights from a Global Survey of People with Type 2 Diabetes. Diabetes, 73(Supplement_1).
• RIDDELL MC, HELLER SR, ASONG M, CARSTENSEN L, WATT SK & WOO VC (2024) 830-P: No Evidence of Increased Physical Activity–Related Hypoglycemia with Once-Weekly Insulin Icodec vs. Once-Daily Basal Insulin in Type 2 Diabetes—ONWARDS 1–5. Diabetes, 73(Supplement_1).
• Robertson E, Sutcliffe J, Connor R & Heller SR (2024) The type 1 diabetes grand challenge: The potential for transformative impact from the largest ever investment, £50 million and collaborative thinking across the UK. Diabetic Medicine, 41(7).
• Svensson CH, Fabricius TW, Verhulst CEM, Kristensen PL, Tack CJ, Heller SR, Amiel SA, McCrimmon RJ, Evans M, Holst JJ , de Galan BE et al (2024) Association between recent exposure to continuous glucose monitoring‐recorded hypoglycaemia and counterregulatory and symptom responses to subsequent controlled hypoglycaemia in people with type 1 diabetes. Diabetes, Obesity and Metabolism.
• Rosenstock J, Bajaj HS, Lingvay I & Heller SR (2024) Clinical perspectives on the frequency of hypoglycemia in treat-to-target randomized controlled trials comparing basal insulin analogs in type 2 diabetes: a narrative review. BMJ Open Diabetes Research & Care, 12(3), e003930-e003930.
• Berthon W, McGurnaghan SJ, Blackbourn LAK, Mellor J, Gibb FW, Heller S, Kennon B, McCrimmon RJ, Philip S, Sattar N , McKeigue PM et al (2024) Ongoing burden and recent trends in severe hospitalised hypoglycaemia events in people with type 1 and type 2 diabetes in Scotland: A nationwide cohort study 2016–2022. Diabetes Research and Clinical Practice, 210, 111642-111642.
• Sander SE, Johansen RF, Caunt S, Søndergaard E, Rolver MG, Sandbæk A, Heller S, Kristensen PL & Molsted S (2024) A Cross-sectional Study on the Impact of Educational Status on Physical Activity Level in Danish and English Adults With Type 1 Diabetes. Canadian Journal of Diabetes, 48(3), 204-210.e1.
• Elneima O, McAuley HJC, Leavy OC, Chalmers JD, Horsley A, Ho L-P, Marks M, Poinasamy K, Raman B, Shikotra A , Singapuri A et al (2023) Cohort profile: post-hospitalisation COVID-19 (PHOSP-COVID) study. International Journal of Epidemiology. View this article in WRRO
• Brightling CE, Evans RA, Singapuri A, Smith N, Wain LV, Brightling CE, Evans RA, Wain LV, Chalmers JD, Harris VC , Ho LP et al (2023) Long COVID research: an update from the PHOSP-COVID Scientific Summit. The Lancet Respiratory Medicine, 11(11), e93-e94.
• Raman B, McCracken C, Cassar MP, Moss AJ, Finnigan L, Samat AHA, Ogbole G, Tunnicliffe EM, Alfaro-Almagro F, Menke R , Xie C et al (2023) Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study. The Lancet Respiratory Medicine, 11(11), 1003-1019.
• MAHMOUDI Z, DIVILLY P, MARTINE-EDITH G, BOIROUX D, ZAREMBA N, SOEHOLM U, GOMES M, VAAG AA, SPEIGHT J, DE GALAN BE , PEDERSEN-BJERGAARD U et al (2023) 391-P: Individualized Optimization of Duration and Threshold of Sensor Hypoglycemia Improves Identification of Symptomatic Hypoglycemia Episodes—Hypo-METRICS Study. Diabetes, 72(Supplement_1).
• AMIEL SA, TOSCHI E, HELLER SR, STADLER MA, CHOUDHARY P & DE ZOYSA N (2023) 390-P: Improving Quality of Life and Self-Efficacy through a Hypoglycemia Management Program—The HARPdoc Randomised Controlled Trial. Diabetes, 72(Supplement_1).
• Søholm U, Broadley M, Zaremba N, Divilly P, Nefs G, Carlton J, Mader JK, Baumann PM, Gomes M, Martine-Edith G , Pollard DJ et al (2023) Psychometric properties of an innovative smartphone application to investigate the daily impact of hypoglycemia in people with type 1 or type 2 diabetes: the Hypo-METRICS app. PLoS ONE, 18(3).
• Ravindrarajah R, Sutton M, Reeves D, Cotterill S, Mcmanus E, Meacock R, Whittaker W, Soiland-Reyes C, Heller S, Bower P & Kontopantelis E (2023) Referral to the NHS Diabetes Prevention Programme and conversion from nondiabetic hyperglycaemia to type 2 diabetes mellitus in England: a matched cohort analysis. PLoS Medicine, 20(2).
• Heller S, Battelino T, Bailey TS, Pieber TR, Hövelmann U, Plum‐Mörschel L, Melgaard AE, Aronson R, DiMeglio LA, Johansen T & Danne T (2023) Integrated safety and efficacy analysis of dasiglucagon for treatment of severe hypoglycaemia in individuals with type 1 diabetes. Diabetes, Obesity and Metabolism.
• Phillip M, Nimri R, Bergenstal RM, Barnard-Kelly K, Danne T, Hovorka R, Kovatchev BP, Messer LH, Parkin CG, Ambler-Osborn L , Amiel SA et al (2023) Consensus Recommendations for the Use of Automated Insulin Delivery Technologies in Clinical Practice. Endocrine Reviews, 44(2), 254-280.
• Seaquist ER, Teff K & Heller SR (2022) Impaired Awareness of Hypoglycemia in Type 1 Diabetes: A Report of An NIDDK Workshop in October 2021. Diabetes Care, 45(12), 2799-2805.
• Chatwin H, Broadley M, Hendrieckx C, Carlton J, Heller S, Amiel SA, de Galan B, McCrimmon RJ, Pedersen-Bjergaard U, Pouwer F & Speight J (2022) The impact of hypoglycaemia on quality of life among adults with type 1 diabetes : results from “YourSAY: Hypoglycaemia”. Journal of Diabetes and its Complications. View this article in WRRO
• Divilly P, Zaremba N, Mahmoudi Z, Søholm U, Pollard DJ, Broadley M, Abbink EJ, de Galan B, Pedersen-Bjergaard U, Renard E , Evans M et al (2022) Hypo-METRICS: Hypoglycaemia - MEasurement, ThResholds and ImpaCtS - A multi-country clinical study to define the optimal threshold and duration of sensor-detected hypoglycaemia that impact the experience of hypoglycaemia, quality of life and health economic outcomes: the study protocol.. Diabet Med, e14892. View this article in WRRO
• Poole AP, Finnis ME, Anstey J, Bellomo R, Bihari S, Biradar V, Doherty S, Eastwood G, Finfer S, French CJ , Heller S et al (2022) The effect of a liberal approach to glucose control in critically ill patients with type 2 diabetes: a multicenter, parallel-group, open-label randomized clinical trial. American Journal of Respiratory and Critical Care Medicine, 206(7), 874-882.
• Amiel SA, Potts L, Goldsmith K, Jacob P, Smith EL, Gonder-Frederick L, Heller S, Toschi E, Brooks A, Kariyawasam D , Choudhary P et al (2022) A parallel randomised controlled trial of the Hypoglycaemia Awareness Restoration Programme for adults with type 1 diabetes and problematic hypoglycaemia despite optimised self-care (HARPdoc).. Nat Commun, 13(1), 2229.
• Evans RA, Leavy OC, Richardson M, Elneima O, McCauley HJC, Shikotra A, Singapuri A, Sereno M, Saunders RM, Harris VC , Houchen-Wolloff L et al (2022) Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study. The Lancet Respiratory Medicine. View this article in WRRO
• Houchen-Wolloff L, Poinasamy K, Holmes K, Tarpey M, Hastie C, Raihani K, Rogers N, Smith N, Adams D, Burgess P , Clark J et al (2022) Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19. Thorax, 77(7), 717-720.
• Jacob P, Potts L, Maclean RH, de Zoysa N, Rogers H, Gonder-Frederick L, Smith EL, Kariyawasam D, Brooks A, Heller S , Toschi E et al (2022) Characteristics of adults with type 1 diabetes and treatment-resistant problematic hypoglycaemia: a baseline analysis from the HARPdoc RCT. Diabetologia.
• Maclean RH, Jacob P, Choudhary P, Heller SR, Toschi E, Kariyawasam D, Brooks A, Kendall M, de Zoysa N, Gonder-Frederick LA & Amiel SA (2022) Hypoglycemia subtypes in type 1 diabetes : an exploration of the Hypoglycemia Fear Survey-II. Diabetes Care.
• Heller S & Novodvorsky P (2022) Hypoglycaemia in diabetes. Medicine.
• Coolen M, Broadley M, Hendrieckx C, Chatwin H, Clowes M, Heller S, de Galan BE, Speight J & Pouwer F (2021) The impact of hypoglycemia on quality of life and related outcomes in children and adolescents with type 1 diabetes: a systematic review. PLoS ONE, 16(12). View this article in WRRO
• Heller SR, Durrant A & Tandon N (2021) Insulin, the patient, and the health professional. The Lancet, 398(10313), 1785-1786.
• Bernjak A, Iqbal A, Heller S & Clayton R (2021) Hypoglycaemia combined with mild hypokalaemia reduces the heart rate and causes abnormal pacemaker activity in a computational model of a human sinoatrial cell.. Journal of the Royal Society Interface, 18(184). View this article in WRRO
• Pieber TR, Bajaj HS, Heller SR, Jia T, Khunti K, Klonoff DC, Ladelund S, Leiter LA, Wagner L & Philis-Tsimikas A (2021) Impact of kidney function on the safety and efficacy of insulin degludec versus insulin glargine U300 in people with type 2 diabetes : a post hoc analysis of the CONCLUDE trial. Diabetes, Obesity and Metabolism.
• Matlock KA, Broadley M, Hendrieckx C, Clowes M, Sutton A, Heller SR, de Galan BE, Pouwer F, Speight J & Hypo-RESOLVE consortium (2021) Changes in quality of life following hypoglycaemia in adults with type 2 diabetes: A systematic review of longitudinal studies. Diabetic Medicine. View this article in WRRO
• Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB, Lone NI, Leavy OC , Daines L et al (2021) Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.. The Lancet Respiratory Medicine, 9(11), 1275-1287. View this article in WRRO
• Chatwin H, Broadley M, Valdersdorf Jensen M, Hendrieckx C, Carlton J, Heller S, Amiel S, de Galan B, Hermanns N, Finke-Groene K , Speight J et al (2021) ‘Never again will I be carefree’: a qualitative study of the impact of hypoglycemia on quality of life among adults with type 1 diabetes. BMJ Open Diabetes Research & Care, 9(1), e002322-e002322.
• HELLER SR, BATTELINO T, BAILEY TS, TEHRANCHI R, KLAFF LJ, PIEBER T, HÖVELMANN U, PLUM-MOERSCHEL L, MELGAARD AE, ARONSON R , DIMEGLIO L et al (2021) 344-P: Integrated Safety Analysis of Dasiglucagon for Treatment of Severe Hypoglycemia. Diabetes, 70(Supplement_1).
• SILVER RJ, ASONG M, BEGTRUP K, KOEFOED MM, HELLER SR & ROSENSTOCK J (2021) 191-OR: Similar Hypoglycemia Duration with Once-Weekly Insulin Icodec vs. Insulin Glargine U100 in Insulin Naïve or Experienced Patients with T2D. Diabetes, 70(Supplement_1).
• Nguyen TN, Harris K, Woodward M, Chalmers J, Cooper M, Hamet P, Harrap S, Heller S, MacMahon S, Mancia G , Marre M et al (2021) The Impact of Frailty on the Effectiveness and Safety of Intensive Glucose Control and Blood Pressure-Lowering Therapy for People With Type 2 Diabetes: Results From the ADVANCE Trial.. Diabetes Care.
• Moser O, Riddell MC, Eckstein ML, Adolfsson P, Rabasa-Lhoret R, van den Boom L, Gillard P, Nørgaard K, Oliver NS, Zaharieva DP , Battelino T et al (2021) Glucose management for exercise using continuous glucose monitoring: should sex and prandial state be additional considerations? Reply to Yardley JE and Sigal RJ [letter]. Diabetologia, 64, 935-938.
• Fabricius TW, Verhulst CEM, Kristensen PL, Tack CJ, McCrimmon RJ, Heller S, Evans ML, Amiel SA, Pieber TR, de Galan BE & Pedersen-Bjergaard U (2021) Hyperinsulinaemic–hypoglycaemic glucose clamps in human research: a systematic review of the literature. Diabetologia, 64(4), 727-736. View this article in WRRO
• von Herrath M, Bain SC, Bode B, Clausen JO, Coppieters K, Gaysina L, Gumprecht J, Hansen TK, Mathieu C, Morales C , Mosenzon O et al (2021) Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Diabetes and Endocrinology, 9(4), 212-224.
• Chatwin H, Broadley M, Speight J, Cantrell A, Sutton A, Heller S, de Galan B, Hendrieckx C & Pouwer F (2021) The impact of hypoglycaemia on quality of life outcomes among adults with type 1 diabetes: A systematic review. Diabetes Research and Clinical Practice, 174, 108752-108752.
• Stanton‐Fay SH, Hamilton K, Chadwick PM, Lorencatto F, Gianfrancesco C, de Zoysa N, Coates E, Cooke D, McBain H, Heller SR & Michie S (2021) The DAFNEplus programme for sustained type 1 diabetes self-management: Intervention development using the Behaviour Change Wheel. Diabetic Medicine. View this article in WRRO
• Ali Abdelhamid Y, Bernjak A, Phillips LK, Summers MJ, Weinel LM, Lange K, Chow E, Kar P, Horowitz M, Heller S & Deane AM (2021) Nocturnal Hypoglycemia in Patients With Diabetes Discharged From ICUs: A Prospective Two-Center Cohort Study*. Critical Care Medicine, 49(4), 636-649.
• Carlton J, Leaviss J, Pouwer F, Hendrieckx C, Broadley MM, Clowes M, McCrimmon RJ, Heller SR & Speight J (2021) The suitability of patient-reported outcome measures used to assess the impact of hypoglycaemia on quality of life in people with diabetes: a systematic review using COSMIN methods.. Diabetologia.
• Bernjak A, Novodvorsky P, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Marques JLB, Jacques RM, Campbell MJ , Sheridan PJ et al (2021) Cardiac arrhythmias and electrophysiologic responses during spontaneous hyperglycaemia in adults with type 1 diabetes mellitus. Diabetes & Metabolism, 101237-101237.
• Phillip M, Mathieu C, Lind M, Araki E, Bartolo P, Bergenstal R, Heller S, Hansen L, Scheerer MF, Thoren F , Arya N et al (2021) Long‐term efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes: pooled 52‐week outcomes from the DEPICT‐1 and ‐2 studies outcomes from the DEPICT‐1 and ‐2 studies. Diabetes, Obesity and Metabolism, 23(2), 549-560. View this article in WRRO
• Coates E, Amiel S, Baird W, Benaissa M, Brennan A, Campbell M, Chadwick P, Chater T, Choudhary P, Cooke D , Cooper C et al (2021) Protocol for a cluster randomised controlled trial of the DAFNEplus (Dose Adjustment for Normal Eating) intervention compared with 5x1 DAFNE : a lifelong approach to promote effective self-management in adults with type 1 diabetes. BMJ Open, 11(1). View this article in WRRO
• Moser O, Riddell MC, Eckstein ML, Adolfsson P, Rabasa-Lhoret R, van den Boom L, Gillard P, Nørgaard K, Oliver NS, Zaharieva DP , Battelino T et al (2020) Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes (EASD) and of the International Society for Pediatric and Adolescent Diabetes (ISPAD) endorsed by JDRF and supported by the American Diabetes Association (ADA). Diabetologia, 63(12), 2501-2520.
• Ravindrarajah R, Reeves D, Howarth E, Meacock R, Soiland-Reyes C, Cotterill S, Whittaker W, Heller S, Sutton M, Bower P & Kontopantelis E (2020) Epidemiology and determinants of non-diabetic hyperglycaemia and its conversion to type 2 diabetes mellitus, 2000–2015: cohort population study using UK electronic health records. BMJ Open, 10(9), e040201-e040201.
• Everett CC, Reynolds C, Fernandez C, Stocken DD, Sharples LD, Sathyapalan T, Heller S, Storey RF & Ajjan RA (2020) Rationale and design of the LIBERATES trial : protocol for a randomised controlled trial of flash glucose monitoring for optimisation of glycaemia in individuals with type 2 diabetes and recent myocardial infarction. Diabetes and Vascular Disease Research, 17(5). View this article in WRRO
• Heller SR, Peyrot M, Oates SK & Taylor AD (2020) Hypoglycemia in patient with type 2 diabetes treated with insulin: it can happen. BMJ Open Diabetes Research & Care, 8(1). View this article in WRRO
• Winkley K, Upsher R, Stahl D, Pollard D, Kasera A, Brennan A, Heller S & Ismail K (2020) Psychological interventions to improve self-management of type 1 and type 2 diabetes: a systematic review. Health Technology Assessment, 24(28). View this article in WRRO
• MACLEAN RH, JACOB P, HAYWOOD S, CHOUDHARY P, HELLER SR, TOSCHI E, KARIYAWASAM D, ANDERBRO TC & AMIEL SA (2020) 156-OR: Fear of Hypoglycemia in People with Type 1 Diabetes and Problematic Hypoglycaemia: A Mismatch between Worry and Behaviour?. Diabetes, 69(Supplement_1).
• Bradburn MJ, Lee EC, White DA, Hind D, Waugh NR, Cooke DD, Hopkins D, Mansell P & Heller SR (2020) Treatment effects may remain the same even when trial participants differed from the target population. Journal of Clinical Epidemiology. View this article in WRRO
• Winkley K, Upsher R, Stahl D, Pollard D, Brennan A, Heller SR & Ismail K (2020) Psychological interventions to improve glycemic control in adults with type 2 diabetes: a systematic review and meta-analysis. BMJ Open Diabetes Research & Care, 8(1). View this article in WRRO
• Heller S, Lingvay I, Marso SP, Philis‐Tsimikas A, Pieber TR, Poulter NR, Pratley RE, Hachmann‐Nielsen E, Kvist K, Lange M , Moses AC et al (2020) Risk of severe hypoglycaemia and its impact in type 2 diabetes in DEVOTE. Diabetes, Obesity and Metabolism. View this article in WRRO
• Philis-Tsimikas A, Klonoff DC, Khunti K, Bajaj HS, Leiter LA, Hansen MV, Troelsen LN, Ladelund S, Heller S & Pieber TR (2020) Risk of hypoglycaemia with insulin degludec versus insulin glargine U300 in insulin-treated patients with type 2 diabetes : the randomised, head-to-head CONCLUDE trial. Diabetologia, 63(4), 698-710. View this article in WRRO
• Sinclair AJ, Heller SR, Pratley RE, Duan R, Heine RJ, Festa A & Kiljański J (2020) Evaluating glucose‐lowering treatment in older people with diabetes : lessons from the IMPERIUM trial. Diabetes, Obesity and Metabolism. View this article in WRRO
• Heller SR, Gianfrancesco C, Taylor C & Elliott J (2020) What are the characteristics of the best type 1 diabetes patient education programmes (from diagnosis to long‐term care), do they improve outcomes and what is required to make them more effective?. Diabetic Medicine, 37(4), 545-554.
• Bernjak A, Chow E, Robinson EJ, Freeman J, Marques JLB, Macdonald IA, Sheridan PJ & Heller SR (2020) Influence of cardiac autonomic neuropathy on cardiac repolarisation during incremental adrenaline infusion in type 1 diabetes. Diabetologia. View this article in WRRO
• Winkley K, Upsher R, Stahl D, Pollard D, Brennan A, Heller S & Ismail K (2020) Systematic review and meta‐analysis of randomized controlled trials of psychological interventions to improve glycaemic control in children and adults with type 1 diabetes. Diabetic Medicine. View this article in WRRO
• Galan BE, McCrimmon RJ, Ibberson M, Heller SR, Choudhary P, Pouwer F, Speight J, Carlton J, Pieber TR, Rosilio M , Tack CJ et al (2020) Reducing the burden of hypoglycaemia in people with diabetes through increased understanding : design of the Hypoglycaemia REdefining SOLutions for better liVEs (Hypo‐RESOLVE) project. Diabetic Medicine. View this article in WRRO
• Philis‐Tsimikas A, Lane W, Pedersen‐Bjergaard U, Wysham C, Bardtrum L, Harring S & Heller S (2020) The relationship between HbA1c and hypoglycaemia in patients with diabetes treated with insulin degludec versus insulin glargine 100 units/mL. Diabetes, Obesity and Metabolism. View this article in WRRO
• Seaquist ER, Blonde L, McGill JB, Heller SR, Kendall DM, Bumpass JB, Pompilio FM & Grant ML (2020) Hypoglycaemia is reduced with use of inhaled Technosphere ® Insulin relative to insulin aspart in type 1 diabetes mellitus. Diabetic Medicine, 37(5), 752-759.
• Flatt AJS, Little SA, Speight J, Leelarathna L, Walkinshaw E, Tan HK, Bowes A, Lubina-Solomon A, Holmes-Truscott E, Chadwick TJ , Wood R et al (2020) Predictors of Recurrent Severe Hypoglycemia in Adults With Type 1 Diabetes and Impaired Awareness of Hypoglycemia During the HypoCOMPaSS Study. Diabetes Care, 43(1), 44-52.
• Heller S, Lingvay I, Marso SP, Philis‐Tsimikas A, Pieber TR, Poulter NR, Pratley RE, Hachmann‐Nielsen E, Kvist K, Lange M , Moses AC et al (2020) Development of a hypoglycaemia risk score to identify high‐risk individuals with advanced type 2 diabetes in DEVOTE. Diabetes, Obesity and Metabolism, 22(12), 2248-2256.
• Moran R, Butt J, Heller S, Hinks J, Kerridge L, Samuels M & Hanney S (2019) Health research systems in change: the case of ‘Push the Pace’ in the National Institute for Health Research. Health Research Policy and Systems, 17(1). View this article in WRRO
• Heller SR, Buse JB, Ratner R, Seaquist E, Bardtrum L, Hansen CT, Tutkunkardas D & Moses AC (2019) Redefining hypoglycemia in clinical trials: validation of definitions recently adopted by the American Diabetes Association/European Association for the study of diabetes. Diabetes Care. View this article in WRRO
• Johnson B, Norman P, Sanders T, Elliott J, Whitehead V, Campbell F, Hammond P, Ajjan R & Heller S (2019) Working with insulin, carbohydrates, ketones and exercise to manage diabetes (WICKED) : evaluation of a self‐management course for young people with Type 1 diabetes. Diabetic Medicine. View this article in WRRO
• Speight J, Holmes-Truscott E, Little SA, Leelarathna L, Walkinshaw E, Tan HK, Bowes A, Kerr D, Flanagan D, Heller SR , Evans ML et al (2019) Satisfaction with the Use of Different Technologies for Insulin Delivery and Glucose Monitoring Among Adults with Long-Standing Type 1 Diabetes and Problematic Hypoglycemia: 2-Year Follow-Up in the HypoCOMPaSS Randomized Clinical Trial. Diabetes Technology & Therapeutics, 21(11), 619-626.
• Battelino T, Danne T, Bergenstal RM, Amiel SA, Beck R, Biester T, Bosi E, Buckingham BA, Cefalu WT, Close KL , Cobelli C et al (2019) Clinical targets for continuous glucose monitoring data interpretation : recommendations from the international consensus on time in range. Diabetes Care, 42(8), 1593-1603. View this article in WRRO
• Mosenzon O, Blicher TM, Rosenlund S, Eriksson JW, Heller S, Hels OH, Pratley R, Sathyapalan T, Desouza C, Abramof R , Alpenidze D et al (2019) Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial. The Lancet Diabetes & Endocrinology, 7(7), 515-527.
• Heller SR, DeVries JH, Wysham C, Hansen CT, Hansen MV & Frier BM (2019) Lower rates of hypoglycaemia in older individuals with type 2 diabetes using insulin degludec versus insulin glargine U100 : results from SWITCH 2. Diabetes, Obesity and Metabolism, 21(7), 1634-1641. View this article in WRRO
• Pollock RF, Heller S, Pieber TR, Woo V, Gundgaard J, Hallén N, Luckevich M, Tutkunkardas D & Zinman B (2019) Short‐term cost‐utility of degludec versus glargine U100 for patients with type 2 diabetes at high risk of hypoglycaemia and cardiovascular events: A Canadian setting (DEVOTE 9). Diabetes, Obesity and Metabolism, 21(7), 1706-1714. View this article in WRRO
• Amiel SA, Choudhary P, Jacob P, Smith EL, De Zoysa N, Gonder-Frederick L, Kendall M, Heller S, Brooks A, Toschi E , Kariyawasam D et al (2019) Hypoglycaemia Awareness Restoration Programme for People with Type 1 Diabetes and Problematic Hypoglycaemia Persisting Despite Optimised Self-care (HARPdoc): protocol for a group randomised controlled trial of a novel intervention addressing cognitions. BMJ Open, 9(6), e030356-e030356.
• Heller SR (2019) Robert Tattersall, a Diabetes Physician Ahead of His Time. Diabetes Care, 42(6), 1005-1008.
• Group TIHS, Amiel SA, Aschner P, Childs B, Cryer PE, de Galan BE, Frier BM, Gonder-Frederick L, Heller SR, Jones T , Khunti K et al (2019) Hypoglycaemia, cardiovascular disease, and mortality in diabetes: epidemiology, pathogenesis, and management. The Lancet Diabetes & Endocrinology, 7(5), 385-396. View this article in WRRO
• Sanders T, Elliott J, Norman P, Johnson B & Heller S (2019) Disruptive illness contexts and liminality in the accounts of young people with type 1 diabetes. Sociology of Health & Illness, 41(7), 1289-1304.
• Iqbal A, Prince LR, Novodvorsky P, Bernjak A, Thomas MR, Birch L, Lambert D, Kay LJ, Wright FJ, Macdonald IA , Jacques RM et al (2019) Effect of Hypoglycemia on Inflammatory Responses and the Response to Low Dose Endotoxemia in Humans.. Journal of Clinical Endocrinology and Metabolism, 104(4), 1187-1199. View this article in WRRO
• Dunkley AJ, Fitzpatrick C, Gray LJ, Waheed G, Heller SR, Frier BM, Davies MJ, Khunti K & Group OBOTPCDS (2019) Incidence and severity of hypoglycaemia in type 2 diabetes by treatment regimen: a UK multi‐site 12‐month prospective observational study. Diabetes Obesity and Metabolism. View this article in WRRO
• Danne T, Garg S, Peters AL, Buse JB, Mathieu C, Pettus JH, Alexander CM, Battelino T, Ampudia-Blasco FJ, Bode BW , Cariou B et al (2019) International Consensus on Risk Management of Diabetic Ketoacidosis in Patients With Type 1 Diabetes Treated With Sodium–Glucose Cotransporter (SGLT) Inhibitors. Diabetes Care, 42(6), 1147-1154.
• Heller S & Novodvorsky P (2019) Hypoglycaemia in diabetes. Medicine, 47(1), 52-58.
• Bowering K, Rodbard HW, Russell-Jones D, Bode B, Harris S, Piletic M, Heller S, Woo V, Babu V, Dethlefsen C & Mathieu C (2019) Investigating the Association Between Baseline Characteristics (HbA1c and Body Mass Index) and Clinical Outcomes of Fast-Acting Insulin Aspart in People with Diabetes: A Post Hoc Analysis. Diabetes Therapy, 10(1), 177-188.
• Heller S, Meneghini L, Nikolajsen A, Kragh N, Lewis HB, Saretsky T, Kosmas CE & Lloyd A (2019) Towards a better understanding of postprandial hyperglycemic episodes in people with diabetes: impact on daily functioning. Current Medical Research and Opinion, 35(3), 525-533.
• Chow E, Iqbal A, Walkinshaw E, Phoenix F, Macdonald IA, Storey RF, Ajjan R & Heller SR (2018) Prolonged Prothrombotic Effects of Antecedent Hypoglycemia in Individuals With Type 2 Diabetes. Diabetes Care, 41(12), 2625-2633. View this article in WRRO
• Campbell F, Lawton J, Rankin D, Clowes M, Coates E, Heller S, De Zoysa N, Elliott J & Breckenridge J (2018) Follow-Up Support for Effective type 1 Diabetes self-management (The FUSED Model): A systematic review and meta-ethnography of the barriers, facilitators and recommendations for sustaining self-management skills after attending a structured education programme. BMC Health Services Research, 18. View this article in WRRO
• DeVries JH, Bailey TS, Bhargava A, Gerety G, Gumprecht J, Heller S, Lane W, Wysham CH, Zinman B, Bak BA , Hachmann-Nielsen E et al (2018) Day-to-day fasting self-monitored blood glucose variability is associated with risk of hypoglycaemia in insulin-treated patients with type 1 and type 2 diabetes: a post hoc analysis of the SWITCH trials. Diabetes, Obesity and Metabolism. View this article in WRRO
• Sanders T, Elliott J, Norman P, Johnson B & Heller S (2018) Experiences of self-management among young adults with type 1 diabetes in the context of a structured education programme: a qualitative study. Diabetic Medicine, 35(11), 1531-1537. View this article in WRRO
• White WB, Jalil F, Cushman WC, Bakris GL, Bergenstal R, Heller SR, Liu Y, Mehta C, Zannad F & Cannon CP (2018) Average Clinician‐Measured Blood Pressures and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Ischemic Heart Disease in the EXAMINE Trial. Journal of the American Heart Association, 7(20).
• Heller S, Bowering K, Raskin P, Liebl A, Buchholtz K, Gorst-Rasmussen A & Pieber TR (2018) The effect of basal-bolus therapy varies with baseline 1,5-anhydroglucitol level in people with Type 2 diabetes: a post hoc analysis. Diabetic Medicine, 35(9), 1273-1278. View this article in WRRO
• Novodvorsky P, Bernjak A, Robinson EJ, Iqbal A, Macdonald IA, Jacques RM, Marques JLB, Sheridan PJ & Heller SR (2018) Salbutamol-induced electrophysiological changes show no correlation with electrophysiological changes during hyperinsulinaemic-hypoglycaemic clamp in young people with Type 1 diabetes.. Diabetic Medicine, 35(9), 1264-1272. View this article in WRRO
• HELLER SR, HANS DEVRIES J, WYSHAM CH, HANSEN CT, HANSEN MV & FRIER BM (2018) Insulin Degludec Has Lower Hypoglycemia Risk than Insulin Glargine U100 in Older People with Type 2 Diabetes (T2D). Diabetes, 67(Supplement_1).
• Korsatko S, Jensen L, Brunner M, Sach‐Friedl S, Tarp MD, Holst AG, Heller SR & Pieber TR (2018) Effect of once‐weekly semaglutide on the counterregulatory response to hypoglycaemia in people with type 2 diabetes: A randomized, placebo‐controlled, double‐blind, crossover trial. Diabetes, Obesity and Metabolism, 20(11), 2565-2573.
• Pratley RE, Rosenstock J, Heller SR, Sinclair A, Heine RJ, Kiljański J, Brusko CS, Duan R & Festa A (2018) Reduced Glucose Variability With Glucose-Dependent Versus Glucose-Independent Therapies Despite Similar Glucose Control and Hypoglycemia Rates in a Randomized, Controlled Study of Older Patients With Type 2 Diabetes Mellitus. Journal of Diabetes Science and Technology, 12(6), 1184-1191.
• Pollock RF, Chubb B, Valentine WJ & Heller S (2018) Evaluating the cost-effectiveness of insulin detemir versus neutral protamine Hagedorn insulin in patients with type 1 or type 2 diabetes in the UK using a short-term modeling approach. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 11, 217-226. View this article in WRRO
• Iqbal A, Novodvorsky P & Heller SR (2018) Corrigendum: Recent updates on type 1 diabetes mellitus management for clinicians [Diabetes Metab J 2018;42:3-18] doi 10.4093/dmj.2018.42.1.3. Diabetes and Metabolism Journal, 42(2), 177-177. View this article in WRRO
• Cavender MA, White WB, Liu Y, Massaro JM, Bergenstal RM, Mehta CR, Zannad F, Heller S, Cushman WC & Cannon CP (2018) Total Cardiovascular Events Analysis of the EXAMINE Trial in Patients with Type 2 Diabetes and Recent Acute Coronary Syndrome. Clinical Cardiology. View this article in WRRO
• Pollard DJ, Brennan A, Dixon S, Waugh N, Elliott J, Heller S, Lee E, Campbell M, Basarir H & White D (2018) Cost-effectiveness of insulin pumps compared with multiple daily injections both provided with structured education for adults with type 1 diabetes: a health economic analysis of the Relative Effectiveness of Pumps over Structured Education (REPOSE) randomised controlled trial. BMJ Open, 8(4). View this article in WRRO
• White WB, Heller SR, Cannon CP, Howitt H, Khunti K & Bergenstal RM (2018) Alogliptin in Patients with Type 2 Diabetes Receiving Metformin and Sulfonylurea Therapies in the EXAMINE Trial. The American Journal of Medicine, 131(7), 813-819.e5.
• Chatterjee S, Davies MJ, Heller S, Speight J, Snoek FJ & Khunti K (2018) Technology and chronic disease management – Authors' reply. The Lancet Diabetes & Endocrinology, 6(2), 91-92.
• Iqbal A, Novodvorsky P & Heller SR (2018) Recent updates on type 1 diabetes mellitus management for clinicians. Diabetes and Metabolism Journal, 42(1), 3-18. View this article in WRRO
• Chatterjee S, Davies MJ, Heller S, Speight J, Snoek FJ & Khunti K (2018) Diabetes structured self-management education programmes: a narrative review and current innovations. The Lancet Diabetes & Endocrinology, 6(2), 130-142.
• Danne T, Nimri R, Battelino T, Bergenstal RM, Close KL, DeVries JH, Garg S, Heinemann L, Hirsch I, Amiel SA , Beck R et al (2017) International Consensus on Use of Continuous Glucose Monitoring. Diabetes Care, 40(12), 1631-1640.
• Hwang Y-C, Morrow DA, Cannon CP, Liu Y, Bergenstal R, Heller S, Mehta C, Cushman W, Bakris GL, Zannad F & White WB (2017) High-sensitivity C-reactive Protein, Low-Density Lipoprotein Cholesterol, and Cardiovascular Outcomes in Patients with Type 2 Diabetes in the EXAMINE (Examination of Cardiovascular Outcomes With Alogliptin Versus Standard of Care) Trial.. Diabetes, Obesity and Metabolism. View this article in WRRO
• Pieber TR, Marso SP, McGuire DK, Zinman B, Poulter NR, Emerson SS, Pratley RE, Woo V, Heller S, Lange M , Brown-Frandsen K et al (2017) DEVOTE 3: temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality. Diabetologia. View this article in WRRO
• Mitchell SJ, Hine J, Vening J, Montague J, Evans S, Shaw KM, Frier BM, Heller SR & Russell-Jones DL (2017) A UK Civil Aviation Authority protocol to allow pilots with insulin-treated diabetes to fly commercial aircraft. The Lancet Diabetes & Endocrinology, 5(9), 677-679.
• Heller SR, Pratley RE, Sinclair A, Festa A, Kiljanski J, Brusko CS, Duan R & Heine RJ (2017) Glycaemic outcomes of an Individualised treatMent aPproach for oldER vulnerable patIents: A randomised, controlled stUdy in type 2 diabetes Mellitus (IMPERIUM). Diabetes, Obesity and Metabolism. View this article in WRRO
• Kar P, Jones KL, Plummer MP, Ali Abdelhamid Y, Giersch EJ, Summers MJ, Hatzinikolas S, Heller S, Horowitz M & Deane AM (2017) Antecedent Hypoglycemia Does Not Attenuate the Acceleration of Gastric Emptying by Hypoglycemia. The Journal of Clinical Endocrinology & Metabolism, 102(11), 3953-3960.
• Iqbal A & Heller SR (2017) The role of structured education in the management of hypoglycaemia. Diabetologia. View this article in WRRO
• Festa A, Heller SR, Seaquist E, Duan R, Hadjiyianni I & Fu H (2017) Association between mild and severe hypoglycemia in people with type 2 diabetes initiating insulin. Journal of Diabetes and its Complications, 31(6), 1047-1052.
• Novodvorsky P, Bernjak A, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Parekh B, Jacques RM, Marques JLB , Sheridan PJ et al (2017) Diurnal Differences in Risk of Cardiac Arrhythmias During Spontaneous Hypoglycemia in Young People With Type 1 Diabetes. Diabetes Care, 40(5), 655-662. View this article in WRRO
• Norwood P, Chen R, Jaeckel E, Lingvay I, Jarlov H, Lehmann L & Heller S (2017) Rates of hypoglycaemia are lower in patients treated with insulin degludec/liraglutide (IDegLira) than with IDeg or insulin glargine regardless of the hypoglycaemia definition used. Diabetes, Obesity and Metabolism. View this article in WRRO
• Russell-Jones D, Bode BW, De Block C, Franek E, Heller SR, Mathieu C, Philis-Tsimikas A, Rose L, Woo VC, Østerskov AB , Graungaard T et al (2017) Fast-Acting Insulin Aspart Improves Glycemic Control in Basal-Bolus Treatment for Type 1 Diabetes: Results of a 26-Week Multicenter, Active-Controlled, Treat-to-Target, Randomized, Parallel-Group Trial (Onset 1).. Diabetes Care.
• Heller S, White D, Lee E, Lawton J, Pollard D, Waugh N, Amiel S, Barnard K, Beckwith A, Brennan A , Campbell M et al (2017) A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial. Health Technology Assessment, 21(20), 1-278. View this article in WRRO
• Heller S, Amiel S, Campbell M, Choudhary P, Cooper C, Dimairo M, Elliott J, Hammond P, Lee E, Lindsay R , Waugh N et al (2017) Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE). BMJ, 356, ---. View this article in WRRO
• Heller SR, Bergenstal RM, White WB, Kupfer S, Bakris GL, Cushman WC, Mehta CR, Nissen SE, Wilson CA, Zannad F , Liu Y et al (2017) Relationship of glycated haemoglobin and reported hypoglycaemia to cardiovascular outcomes in patients with type 2 diabetes and recent acute coronary syndromes: the EXAMINE trial. Diabetes, Obesity and Metabolism. View this article in WRRO
• Lawton J, White D, Rankin D, Elliott J, Taylor C, Cooper C, Heller S & Hallowell N (2017) Staff experiences of closing out a clinical trial involving withdrawal of treatment: qualitative study. Trials, 18. View this article in WRRO
• The International Hypoglycaemia Study GroupEmail (2017) Glucose concentrations of less than 3.0 mmol/l (54 mg/dl) should be reported in clinical trials: a joint position statement of the American Diabetes Association and the Europian Association for the Study of Diabetes. Diabetologia, 60(1), 3-6. View this article in WRRO
• International Hypoglycaemia Study Group (2017) Glucose Concentrations of Less Than 3.0 mmol/L (54 mg/dL) Should Be Reported in Clinical Trials: A Joint Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care, 40(1), 155-157.
• Russell-Jones D, Buchs S, Jensen MM, Hunt B, Valentine WJ & Heller S (2016) Projected Long-Term Outcomes in Patients with Type 1 Diabetes Mellitus Treated with Faster-Acting Insulin Aspart Versus Conventional Insulin Aspart in the UK Setting. Value in Health, 19(7), A671-A671.
• van der Leeuw J, Visseren FLJ, Woodward M, van der Graaf Y, Grobbee DE, Harrap S, Heller S, Mancia G, Marre M, Poulter N , Zoungas S et al (2016) Estimation of individual beneficial and adverse effects of intensive glucose control for patients with type 2 diabetes. Diabetologia, 59(12), 2603-2612. View this article in WRRO
• Rosenstock J, Guerci B, Hanefeld M, Gentile S, Aronson R, Tinahones FJ, Roy-Duval C, Souhami E, Wardecki M, Ye J , Perfetti R et al (2016) Prandial Options to Advance Basal Insulin Glargine Therapy: Testing Lixisenatide Plus Basal Insulin Versus Insulin Glulisine Either as Basal-Plus or Basal-Bolus in Type 2 Diabetes: The GetGoal Duo-2 Trial. Diabetes Care, 39(8), 1318-1328.
• Iqbal A & Heller S (2016) Managing hypoglycaemia. Best Practice & Research Clinical Endocrinology & Metabolism, 30(3), 413-430. View this article in WRRO
• White WB, Kupfer S, Zannad F, Mehta CR, Wilson CA, Lei L, Bakris GL, Nissen SE, Cushman WC, Heller SR , Bergenstal RM et al (2016) Cardiovascular Mortality in Patients With Type 2 Diabetes and Recent Acute Coronary Syndromes From the EXAMINE Trial. Diabetes Care, 39(7), 1267-1273.
• Mader JK, Jensen L, Ingwersen SH, Christiansen E, Heller S & Pieber TR (2016) Pharmacokinetic Properties of Liraglutide as Adjunct to Insulin in Subjects with Type 1 Diabetes Mellitus. Clinical Pharmacokinetics, 55(11), 1457-1463. View this article in WRRO
• Wong MG, Perkovic V, Chalmers J, Woodward M, Li Q, Cooper ME, Hamet P, Harrap S, Heller S, MacMahon S , Mancia G et al (2016) Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON. Diabetes Care, 39(5), 694-700.
• Tan HK, Little SA, Leelarathna L, Walkinshaw E, Lubina-Solomon A, Hosking J, Speight J, Kerr D, Heller SR, Evans ML , Shaw JAM et al (2016) Low–Blood Glucose Avoidance Training Improves Glycemic Variability in Adults With Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia: HypoCOMPaSS Trial. Diabetes Care, 39(4), e56-e58.
• Heller SR, Frier BM, Hersløv ML, Gundgaard J & Gough SCL (2016) Severe hypoglycaemia in adults with insulin-treated diabetes: impact on healthcare resources. Diabetic Medicine, 33(4), 471-477. View this article in WRRO
• Heller S, Mathieu C, Kapur R, Wolden ML & Zinman B (2016) A meta‐analysis of rate ratios for nocturnal confirmed hypoglycaemia with insulin degludec vs. insulin glargine using different definitions for hypoglycaemia. Diabetic Medicine, 33(4), 478-487. View this article in WRRO
• Guerci B, Hanefeld M, Gentile S, Aronson R, Tinahones F, Roy-duval C, Souhami E, Wardecki M, Ye J, Heller S & Rosenstock J (2016) CAD-28: Optimisation de l'utilisation de l'insuline Glargine par l'ajout de lixisénatide prandial vs l'insuline glulisine une fois par jour (GLU-1), ou l'insuline glulisine 3 fois par jour (GLU-3) : GetGoal-Duo2. Diabetes & Metabolism, 42, A31-A31.
• Garg SK & Hirsch IB (2016) Self-Monitoring of Blood Glucose. Diabetes Technology & Therapeutics, 18(S1).
• Heller SR (2016) Blood glucose monitoring had no impact on distress or self-efficacy in people with non-insulin-treated type 2 diabetes. Evidence Based Medicine, 21(1), 20-20.
• Lawton J, Kirkham J, Rankin D, White DA, Elliott J, Jaap A, Smithson WH, Heller S, Gianfrancesco C, Gordon V , Greaves L et al (2016) Who gains clinical benefit from using insulin pump therapy? A qualitative study of the perceptions and views of health professionals involved in the Relative Effectiveness of Pumps over MDI and Structured Education (REPOSE) trial. Diabetic Medicine, 33(2), 243-251.
• Price KJ, Knowles JA, Fox M, Wales JKH, Heller S, Eiser C, Freeman JV, Brennan A, Basirir H, Stevens K & McPherson A (2016) Effectiveness of the Kids in Control of Food (KICk-OFF) structured education course for 11-16 year olds with Type 1 diabetes. Diabetic Medicine, 33(2), 192-203.
• Speight J, Barendse SM, Singh H, Little SA, Inkster B, Frier BM, Heller SR, Rutter MK & Shaw JAM (2016) Characterizing problematic hypoglycaemia: iterative design and preliminary psychometric validation of the Hypoglycaemia Awareness Questionnaire (HypoA-Q). Diabetic Medicine, 33(3), 376-385.
• Lawton J, Kirkham J, White D, Rankin D, Cooper C & Heller S (2015) Uncovering the emotional aspects of working on a clinical trial: a qualitative study of the experiences and views of staff involved in a type 1 diabetes trial. Trials, 16(1). View this article in WRRO
• Kojzar H, Thabit H, Leelarathna L, Wilinska ME, Elleri D, Allen JM, Lubina-Solomon A, Walkinshaw E, Stadler M, Choudhary P , Holzer M et al (2015) Accuracy and Performance of continuous Glucose Monitoring with three Closed-Loop Studies with Home Phase under normal Living Conditions. WIENER KLINISCHE WOCHENSCHRIFT, 127, S145-S146.
• Heller S, Amiel SA & Khunti K (2015) Hypoglycaemia, a global cause for concern. Diabetes Research and Clinical Practice, 110(2), 229-232.
• Tauschmann M, Thabit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P , Wilinska ME et al (2015) Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes. Journal of Diabetes Science and Technology, 9(6), 1346-1347. View this article in WRRO
• Thabit H, Leelarathna L, Wilinska ME, Elleri D, Allen JM, Lubina-Solomon A, Walkinshaw E, Stadler M, Choudhary P, Mader JK , Dellweg S et al (2015) Accuracy of Continuous Glucose Monitoring During Three Closed-Loop Home Studies Under Free-Living Conditions. Diabetes Technology & Therapeutics, 17(11), 801-807. View this article in WRRO
• Kruger J, Pollard DJ, Basarir H, Thokala P, Cooke D, Clark M, Bond R, Heller S & Brennan A (2015) Incorporating Psychological Predictors of Treatment Response into Health Economic Simulation Models: A Case Study in Type 1 Diabetes. Medical Decision Making, 35(7), 872-887. View this article in WRRO
• Heller S, Houwing N, Kragh N, Ploug UJ, Nikolajsen A & Alleman CJM (2015) Investigating the Evidence of the Real-Life Impact of Acute Hyperglycaemia. Diabetes Therapy, 6(3), 389-393. View this article in WRRO
• (2015) Minimizing Hypoglycemia in Diabetes. Diabetes Care, 38(8), 1583-1591.
• Eborall HC, Dallosso HM, McNicol S, Speight J, Khunti K, Davies MJ & Heller SR (2015) Explaining engagement in self-monitoring among participants of the DESMOND Self-monitoring Trial: a qualitative interview study. Family Practice, 32(5), 596-602.
• Treasure J, Kan C, Stephenson L, Warren E, Smith E, Heller S & Ismail K (2015) Developing a theoretical maintenance model for disordered eating in Type 1 diabetes. Diabetic Medicine, 32(12), 1541-1545.
• Cooke D, Bond R, Lawton J, Rankin D, Heller S, Clark M & Speight J (2015) Modeling predictors of changes in glycemic control and diabetes-specific quality of life amongst adults with type 1 diabetes 1 year after structured education in flexible, intensive insulin therapy. Journal of Behavioral Medicine, 38(5), 817-829.
• Elwen FR, Huskinson A, Clapham L, Bottomley MJ, Heller SR, James C, Abbas A, Baxter P & Ajjan RA (2015) An observational study of patient characteristics and mortality following hypoglycemia in the community. BMJ Open Diabetes Research & Care, 3(1). View this article in WRRO
• Thabit H, Elleri D, Leelarathna L, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska ME , Barnard KD et al (2015) Unsupervised home use of an overnight closed-loop system over 3-4 weeks: A pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes. Diabetes, Obesity and Metabolism, 17(5), 452-458. View this article in WRRO
• Pieber TR, Deller S, Korsatko S, Jensen L, Christiansen E, Madsen J & Heller SR (2015) Counter-regulatory hormone responses to hypoglycaemia in people with type 1 diabetes after 4 weeks of treatment with liraglutide adjunct to insulin: a randomized, placebo-controlled, double-blind, crossover trial. Diabetes, Obesity and Metabolism, 17(8), 742-750.
• Young AJ, Thabit H, Heller SR, Evans ML, Amiel SA, Hovorka R & Barnard KD (2015) Holistic Impact of Closed-Loop Technology on People With Type 1 Diabetes. Journal of Diabetes Science and Technology, 9(4), 932-933.
• Dallosso HM, Bodicoat DH, Campbell M, Carey ME, Davies MJ, Eborall HC, Hadjiconstantinou M, Khunti K, Speight J & Heller S (2015) Self-monitoring of blood glucose versus self-monitoring of urine glucose in adults with newly diagnosed Type 2 diabetes receiving structured education: a cluster randomized controlled trial. Diabetic Medicine, 32(3), 414-422.
• Elliott J, Rankin D, Jacques RM, Lawton J, Emery CJ, Campbell MJ, Dixon S & Heller SR (2015) A cluster randomized controlled non-inferiority trial of 5-day Dose Adjustment for Normal Eating (DAFNE) training delivered over 1 week versus 5-day DAFNE training delivered over 5 weeks: the DAFNE 5 × 1-day trial. Diabetic Medicine, 32(3), 391-398. View this article in WRRO
• Ayling K, Brierley S, Johnson B, Heller S & Eiser C (2015) How standard is standard care? Exploring control group outcomes in behaviour change interventions for young people with type 1 diabetes. Psychology & Health, 30(1), 85-103. View this article in WRRO
• Barnard KD, Wysocki T, Thabit H, Evans ML, Amiel S, Heller S, Young A & Hovorka R (2015) Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting. Diabetic Medicine, 32(5), 601-608.
• Ayling K, Brierley S, Johnson B, Heller S & Eiser C (2015) Efficacy of theory-based interventions for young people with type 1 diabetes: A systematic review and meta-analysis. British Journal of Health Psychology, 20(2), 428-446.
• Morrow DA, Cannon CP, Zannad F, Cushman WC, Bakris GL, Nissen SE, Heller SR, Bergenstal RM, Perez AT, Fleck PR , Mehta CR et al (2014) Abstract 17295: Cardiovascular Biomarkers and Long-term Outcomes in Patients with Type 2 Diabetes Mellitus Treated with Alogiptin vs. Placebo in the EXAMINE Trial. Circulation, 130(suppl_2).
• Carey ME, Mandalia PK, Daly H, Gray LJ, Hale R, Martin Stacey L, Taub N, Skinner TC, Stone M, Heller S , Khunti K et al (2014) Increasing capacity to deliver diabetes self-management education: results of the DESMOND lay educator non-randomized controlled equivalence trial. Diabetic Medicine, 31(11), 1431-1438.
• Zoungas S, Chalmers J, Neal B, Billot L, Li Q, Hirakawa Y, Arima H, Monaghan H, Joshi R, Colagiuri S , Cooper ME et al (2014) Follow-up of Blood-Pressure Lowering and Glucose Control in Type 2 Diabetes. New England Journal of Medicine, 371(15), 1392-1406.
• Lawton J, Kirkham J, Rankin D, Barnard K, Cooper CL, Taylor C, Heller S & Elliott J (2014) Perceptions and experiences of using automated bolus advisors amongst people with type 1 diabetes: A longitudinal qualitative investigation. Diabetes Research and Clinical Practice, 106(3), 443-450. View this article in WRRO
• Oliver NS, Evans ML, Hovorka R, Heller S, Johnston DG, Amiel SA & Barnard K (2014) Comment on Doyle et al. Closed-Loop Artificial Pancreas Systems: Engineering the Algorithms. Diabetes Care 2014;37:1191–1197. Diabetes Care, 37(10), e226-e227.
• Zoungas S, Woodward M, Li Q, Cooper ME, Hamet P, Harrap S, Heller S, Marre M, Patel A, Poulter N , Williams B et al (2014) Impact of age, age at diagnosis and duration of diabetes on the risk of macrovascular and microvascular complications and death in type 2 diabetes. Diabetologia, 57(12), 2465-2474.
• White D, Waugh N, Elliott J, Lawton J, Barnard K, Campbell MJ, Dixon S & Heller S (2014) The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled trial. BMJ Open, 4(9), e006204-e006204. View this article in WRRO
• Thabit H, Lubina-Solomon A, Stadler M, Leelarathna L, Walkinshaw E, Pernet A, Allen JM, Iqbal A, Choudhary P, Kumareswaran K , Nodale M et al (2014) Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study. The Lancet Diabetes & Endocrinology, 2(9), 701-709. View this article in WRRO
• Heller S & Chow E (2014) Hypoglycaemia in diabetes. Medicine, 42(12), 727-731.
• Elliott J, Jacques RM, Kruger J, Campbell MJ, Amiel SA, Mansell P, Speight J, Brennan A & Heller SR (2014) Substantial reductions in the number of diabetic ketoacidosis and severe hypoglycaemia episodes requiring emergency treatment lead to reduced costs after structured education in adults with Type 1 diabetes. Diabetic Medicine, 31(7), 847-853. View this article in WRRO
• Pratley R, Heller S & Miller M (2014) Treatment of Type 2 Diabetes Mellitus in the Older Adult: A Review. Endocrine Practice, 20(7), 722-736.
• Gillespie P, O'Shea E, O’Hara MC & Dinneen SF (2014) Cost effectiveness of group follow-up after structured education for type 1 diabetes: a cluster randomised controlled trial. Trials, 15(1).
• Little SA, Leelarathna L, Walkinshaw E, Tan HK, Chapple O, Lubina-Solomon A, Chadwick TJ, Barendse S, Stocken DD, Brennand C , Marshall SM et al (2014) Recovery of Hypoglycemia Awareness in Long-standing Type 1 Diabetes: A Multicenter 2 × 2 Factorial Randomized Controlled Trial Comparing Insulin Pump With Multiple Daily Injections and Continuous With Conventional Glucose Self-monitoring (HypoCOMPaSS). Diabetes Care, 37(8), 2114-2122.
• Chow E, Bernjak A, Williams S, Fawdry RA, Hibbert S, Freeman J, Sheridan PJ & Heller SR (2014) Risk of Cardiac Arrhythmias During Hypoglycemia in Patients With Type 2 Diabetes and Cardiovascular Risk. Diabetes, 63(5), 1738-1747.
• Speight J, Barendse SM, Singh H, Little SA, Rutter MK, Heller SR & Shaw JA (2014) Cognitive, behavioural and psychological barriers to the prevention of severe hypoglycaemia: A qualitative study of adults with type 1 diabetes. SAGE Open Medicine, 2. View this article in WRRO
• Thokala P, Kruger J, Brennan A, Basarir H, Duenas A, Pandor A, Gillett M, Elliott J & Heller S (2014) Assessing the cost-effectiveness of Type 1 diabetes interventions: the Sheffield Type 1 Diabetes Policy Model. Diabetic Medicine, 31(4), 477-486.
• Gouet D, Heller S, Gough S, Oyer D, Jensen K, Kinduryte O & Philis-Tsimikas A (2014) P310 L’hypoglycémie liée à l’activité physique apparaît à une fréquence similaire avec l’insuline dégludec et l’insuline glargine. Diabetes & Metabolism, 40, A101-A101.
• de Zoysa N, Rogers H, Stadler M, Gianfrancesco C, Beveridge S, Britneff E, Choudhary P, Elliott J, Heller S & Amiel SA (2014) A Psychoeducational Program to Restore Hypoglycemia Awareness: The DAFNE-HART Pilot Study: Table 1. Diabetes Care, 37(3), 863-866.
• Eborall HC, Dallosso HM, Daly H, Martin-Stacey L & Heller SR (2014) The face of equipoise - delivering a structured education programme within a randomized controlled trial: qualitative study. Trials, 15(1). View this article in WRRO
• White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, Perez AT, Fleck PR, Mehta CR, Kupfer S , Wilson C et al (2014) Alogliptin after acute coronary syndrome in patients with type 2 diabetes. Austrian Journal of Clinical Endocrinology and Metabolism, 7(2), 77.
• Beer R, Eiser C, Johnson B, Bottrell K, Whitehead V, Elliott J, Gibson C & Heller S (2014) WICKED: The development and evaluation of a psycho-education programme for young people with type 1 diabetes. Journal of Diabetes Nursing, 18(6), 233-237.
• Skinner TC, Khunti K, Carey ME, Dallosso H, Heller S & Davies MJ (2014) Stability and predictive utility, over 3 years, of the illness beliefs of individuals recently diagnosed with Type 2 diabetes mellitus. Diabetic Medicine, 31(10), 1260-1263.
• Koehler G, Heller S, Korsatko S, Roepstorff C, Rasmussen S, Haahr H & Pieber TR (2014) Insulin degludec is not associated with a delayed or diminished response to hypoglycaemia compared with insulin glargine in type 1 diabetes: a double-blind randomised crossover study. Diabetologia, 57(1), 40-49. View this article in WRRO
• Rankin D, Barnard K, Elliott J, Cooke D, Heller S, Gianfrancesco C, Taylor C & Lawton J (2014) Type 1 diabetes patients' experiences of, and need for, social support after attending a structured education programme: a qualitative longitudinal investigation. Journal of Clinical Nursing, 23(19-20), 2919-2927.
• Lawton J, Rankin D, Elliott J, Heller SR, Rogers HA, De Zoysa N & Amiel S (2014) Experiences, Views, and Support Needs of Family Members of People With Hypoglycemia Unawareness: Interview Study: Table 1. Diabetes Care, 37(1), 109-115.
• Rankin D, Elliott J, Heller S, Amiel S, Rogers H, DeZoysa N & Lawton J (2014) Experiences of hypoglycaemia unawareness amongst people with Type 1 diabetes: A qualitative investigation. Chronic Illness, 10(3), 180-191.
• Little SA, Leelarathna L, Barendse SM, Walkinshaw E, Tan HK, Lubina Solomon A, de Zoysa N, Rogers H, Choudhary P, Amiel SA , Heller SR et al (2014) Severe hypoglycaemia in type 1 diabetes mellitus: underlying drivers and potential strategies for successful prevention. Diabetes/Metabolism Research and Reviews, 30(3), 175-190.
• Johnson B, Elliott J, Scott A, Heller S & Eiser C (2014) Medical and psychological outcomes for young adults with Type 1 diabetes: no improvement despite recent advances in diabetes care. Diabetic Medicine, 31(2), 227-231.
• van Dieren S, Kengne AP, Chalmers J, Beulens JWJ, Davis TME, Fulcher G, Heller SR, Patel A, Colagiuri S, Hamet P , Mancia G et al (2014) Intensification of medication and glycaemic control among patients with type 2 diabetes - the ADVANCE trial. Diabetes, Obesity and Metabolism, 16(5), 426-432.
• Ridge K, Thomas S, Jackson P, Pender S, Heller S, Treasure J & Ismail K (2014) Diabetes-Oriented Learning Family Intervention (DOLFIN): a feasibility study evaluating an intervention for carers of young persons with Type 1 diabetes. Diabetic Medicine, 31(1), 55-60.
• Leelarathna L, Little SA, Walkinshaw E, Tan HK, Lubina-Solomon A, Kumareswaran K, Lane AP, Chadwick T, Marshall SM, Speight J , Flanagan D et al (2013) Restoration of Self-Awareness of Hypoglycemia in Adults With Long-Standing Type 1 Diabetes: Hyperinsulinemic-hypoglycemic clamp substudy results from the HypoCOMPaSS trial. Diabetes Care, 36(12), 4063-4070. View this article in WRRO
• Heller S, Bode B, Kozlovski P & Svendsen AL (2013) Meta-analysis of insulin aspart versus regular human insulin used in a basal-bolus regimen for the treatment of diabetes mellitus (在基础-餐时糖尿病治疗方案中使用门冬胰岛素与使用常规人胰岛素对照研究的Meta分析). Journal of Diabetes, 5(4), 482-491. View this article in WRRO
• Urschitz M, Korsatko S, Deller S, Gurban J, Wolf M, Brunner M, Heller SR, Jensen L, Kiyomi F, Christiansen E & Pieber TR (2013) Liraglutide in Combination with Insulin in Type-1-Diabetes: glycemic Effect and Safety in a randomized, double bind Crossover-Study. WIENER KLINISCHE WOCHENSCHRIFT, 125, S14-S14.
• White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, Perez AT, Fleck PR, Mehta CR, Kupfer S , Wilson C et al (2013) Alogliptin after Acute Coronary Syndrome in Patients with Type 2 Diabetes. New England Journal of Medicine, 369(14), 1327-1335.
• Heinemann L (2013) Insulin Pens and New Ways of Insulin Delivery. Diabetes Technology & Therapeutics, 15(S1).
• Grant L, Lawton J, Hopkins D, Elliott J, Lucas S, Clark M, MacLellan I, Davies M, Heller S & Cooke D (2013) Type 1 diabetes structured education: what are the core self-management behaviours?. Diabetic Medicine, 30(6), 724-730.
• Davies M, Heller S, Sreenan S, Sapin H, Adetunji O, Tahbaz A & Vora J (2013) Once-weekly exenatide versus once- or twice-daily insulin detemir. Diabetes Care, 36(5), 1368-1376. View this article in WRRO
• Cooke D, O'Hara MC, Beinart N, Heller S, La Marca R, Byrne M, Mansell P, Dinneen SF, Clark M, Bond R & Speight J (2013) Linguistic and Psychometric Validation of the Diabetes-Specific Quality-of-Life Scale in U.K. English for Adults With Type 1 Diabetes. Diabetes Care, 36(5), 1117-1125. View this article in WRRO
• Eiser C, Johnson B, Brierley S, Ayling K, Young V, Bottrell K, Whitehead V, Elliott J, Scott A & Heller S (2013) Using the Medical Research Council framework to develop a complex intervention to improve delivery of care for young people with Type 1 diabetes. Diabetic Medicine, 30(6), e223-e228.
• Kruger J, Brennan A, Thokala P, Basarir H, Jacques R, Elliott J, Heller S & Speight J (2013) The cost-effectiveness of the Dose Adjustment for Normal Eating (DAFNE) structured education programme: an update using the Sheffield Type 1 Diabetes Policy Model. Diabetic Medicine, 30(10), 1236-1244.
• Cooke D, Bond R, Lawton J, Rankin D, Heller S, Clark M & Speight J (2013) Structured Type 1 Diabetes Education Delivered Within Routine Care: Impact on glycemic control and diabetes-specific quality of life. Diabetes Care, 36(2), 270-272. View this article in WRRO
• Price KJ, Wales J, Eiser C, Knowles J, Heller S, Freeman J, Brennan A, McPherson A & Wellington J (2013) Does an intensive self-management structured education course improve outcomes for children and young people with type 1 diabetes? The Kids In Control OF Food (KICk-OFF) cluster-randomised controlled trial protocol: Table 1. BMJ Open, 3(1). View this article in WRRO
• Bode BW, Buse JB, Fisher M, Garg SK, Marre M, Merker L, Renard E, Russell-Jones DL, Hansen CT, Rana A & Heller SR (2013) Insulin degludec improves glycaemic control with lower nocturnal hypoglycaemia risk than insulin glargine in basal-bolus treatment with mealtime insulin aspart in Type 1 diabetes (BEGIN®Basal-Bolus Type 1): 2-year results of a randomized clinical trial. Diabetic Medicine, 30(11), 1293-1297.
• Cryer PE (2013) Diagnostic Accuracy of an “Amended” Insulin–Glucose Ratio for the Biochemical Diagnosis of Insulinomas. Annals of Internal Medicine, 158(6), 500-500.
• Dinneen SF, O’Hara MC, Byrne M, Smith D, Courtney CH, McGurk C, Heller SR, Newell J, Coffey N, Breen C , O'Scannail M et al (2013) Group follow-up compared to individual clinic visits after structured education for type 1 diabetes: A cluster randomised controlled trial. Diabetes Research and Clinical Practice, 100(1), 29-38.
• Lawton J, Rankin D, Cooke DD, Elliott J, Amiel S & Heller S (2013) Self-treating hypoglycaemia: a longitudinal qualitative investigation of the experiences and views of people with Type 1 diabetes. Diabetic Medicine, 30(2), 209-215.
• Young V, Eiser C, Johnson B, Brierley S, Epton T, Elliott J & Heller S (2013) Eating problems in adolescents with Type 1 diabetes: a systematic review with meta-analysis. Diabetic Medicine, 30(2), 189-198.
• Johnson B, Eiser C, Young V, Brierley S & Heller S (2013) Prevalence of depression among young people with Type 1 diabetes: a systematic review. Diabetic Medicine, 30(2), 199-208.
• Perdomo OJ, Robinson EJ, Suzuki DOH, Heller SR & Marques JLB (2012) Morphological analysis of T-wave in vectorcardiographic leads system by a bi-Gaussian approach in patients under effect of salbutamol.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 5494-5497.
• Little S, Chadwick T, Choudhary P, Brennand C, Stickland J, Barendse S, Olateju T, Leelarathna L, Walkinshaw E, Tan HK , Marshall SM et al (2012) Comparison of Optimised MDI versus Pumps with or without Sensors in Severe Hypoglycaemia (the Hypo COMPaSS trial). BMC Endocrine Disorders, 12(1). View this article in WRRO
• Elliott J, Lawton J, Rankin D, Emery C, Campbell M, Dixon S & Heller S (2012) The 5x1 DAFNE study protocol: a cluster randomised trial comparing a standard 5 day DAFNE course delivered over 1 week against DAFNE training delivered over 1 day a week for 5 consecutive weeks. BMC Endocrine Disorders, 12(1). View this article in WRRO
• Rankin D, Cooke D, Elliott J, Heller S, Lawton J & Amiel S (2012) Supporting self-management after attending a structured education programme: a qualitative longitudinal investigation of type 1 diabetes patients’ experiences and views. BMC Public Health, 12. View this article in WRRO
• Hopkins D, Lawrence IAN, Mansell P, Thompson G, Amiel S, Campbell M & Heller S (2012) Improved biomedical and psychological outcomes 1 year after structured education in flexible insulin therapy for people with type 1 diabetes the U.K. DAFNE experience. Diabetes Care, 35(8), 1638-1642. View this article in WRRO
• Khunti K, Gray LJ, Skinner T, Carey ME, Realf K, Dallosso H, Fisher H, Campbell M, Heller S & Davies MJ (2012) Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care. BMJ, 344(apr26 2), e2333-e2333.
• Heller S, Buse J, Fisher M, Garg S, Marre M, Merker L, Renard E, Russell-Jones D, Philotheou A, Francisco AMO , Pei H et al (2012) Insulin degludec, an ultra-longacting basal insulin, versus insulin glargine in basal-bolus treatment with mealtime insulin aspart in type 1 diabetes (BEGIN Basal-Bolus Type 1): a phase 3, randomised, open-label, treat-to-target non-inferiority trial. The Lancet, 379(9825), 1489-1497.
• Rankin D, Cooke DD, Heller S, Elliott J, Amiel S & Lawton J (2012) Experiences of using blood glucose targets when following an intensive insulin regimen: a qualitative longitudinal investigation involving patients with Type 1 diabetes. Diabetic Medicine, 29(8), 1079-1084.
• Dallosso HM, Eborall HC, Daly H, Martin-Stacey L, Speight J, Realf K, Carey ME, Campbell MJ, Dixon S, Khunti K , Davies MJ et al (2012) Does self monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? the DESMOND SMBG randomised controlled trial protocol. BMC Family Practice, 13. View this article in WRRO
• Brierley S, Eiser C, Johnson B, Young V & Heller S (2012) Working with young adults with Type 1 diabetes: Views of a multidisciplinary care team and implications for service delivery. Diabetic Medicine, 29(5), 677-681.
• Raskin P, Heller S, Honka M, Chang P-C, Boss AH, Richardson PC & Amin N (2012) Pulmonary function over 2 years in diabetic patients treated with prandial inhaled Technosphere Insulin or usual antidiabetes treatment: a randomized trial. Diabetes, Obesity and Metabolism, 14(2), 163-173.
• Gray LJ, Khunti K, Williams S, Goldby S, Troughton J, Yates T, Gray A & Davies MJ (2012) Let’s prevent diabetes: study protocol for a cluster randomised controlled trial of an educational intervention in a multi-ethnic UK population with screen detected impaired glucose regulation. Cardiovascular Diabetology, 11(1), 56-56. View this article in WRRO
• Perdomo OJ, Robinson EJ, Suzuki DOH, Heller SR & Marques JLB (2012) Morphological analysis of T-wave in vectorcardiographic leads system by a bi-Gaussian approach in patients under effect of salbutamol. 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
• Lawton J, Rankin D, Cooke D, Elliott J, Amiel S & Heller S (2012) Patients’ experiences of adjusting insulin doses when implementing flexible intensive insulin therapy: A longitudinal, qualitative investigation. Diabetes Research and Clinical Practice, 98(2), 236-242.
• Zoungas S, Chalmers J, Ninomiya T, Li Q, Cooper ME, Colagiuri S, Fulcher G, de Galan BE, Harrap S, Hamet P , Heller S et al (2012) Association of HbA1c levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds. Diabetologia, 55(3), 636-643.
• Elliott J, Heller SR, Hopkinson HE & Mansell P (2012) Does duration of type 1 diabetes affect the outcomes of structured education?. DIABETOLOGIA, 55, S100-S100.
• Woodward M, Patel A, Zoungas S, Liu L, Pan C, Poulter N, Januszewicz A, Tandon N, Joshi P, Heller S , Neal B et al (2011) Does Glycemic Control Offer Similar Benefits Among Patients With Diabetes in Different Regions of the World?: Results from the ADVANCE trial. Diabetes Care, 34(12), 2491-2495. View this article in WRRO
• Choudhary P, Lonnen K, Emery CJ, Freeman JV, McLeod KM & Heller SR (2011) Relationship Between Interstitial and Blood Glucose During Hypoglycemia in Subjects with Type 2 Diabetes. Diabetes Technology & Therapeutics, 13(11), 1121-1127.
• Doughty RN, Whalley GA, Gamble GD, Baker J, Chalmers J, Cooper M, Cruickshank K, Dixon P, Dunne P, Eccleston D , Jerums G et al (2011) Effects of perindopril-indapamide on left ventricular diastolic function and mass in patients with type 2 diabetes: The ADVANCE Echocardiography Substudy. Journal of Hypertension, 29(7), 1439-1447.
• Heller S (2011) Impaired hypoglycemia awareness. Diabetic Hypoglycemia, 4(1), 1-2.
• Heller S (2011) Impaired awareness of hypoglycemia: Commentary. Diabetic Hypoglycemia, 4(1), 15.
• Rankin D, Cooke DD, Clark M, Heller S, Elliott J & Lawton J (2011) How and why do patients with Type 1 diabetes sustain their use of flexible intensive insulin therapy? A qualitative longitudinal investigation of patients’ self-management practices following attendance at a Dose Adjustment for Normal Eating (DAFNE) cours. Diabetic Medicine, 28(5), 532-538.
• Frier BM, Schernthaner G & Heller SR (2011) Hypoglycemia and Cardiovascular Risks. Diabetes Care, 34(Supplement_2), S132-S137. View this article in WRRO
• Hovorka R, Kumareswaran K, Harris J, Allen JM, Elleri D, Xing D, Kollman C, Nodale M, Murphy HR, Dunger DB , Amiel SA et al (2011) Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies. BMJ, 342(apr13 5), d1855-d1855.
• Heller S (2011) Diabetic hypoglycemia and pregnancy. Diabetic Hypoglycemia, 3(3), 1-2.
• Skinner TC, Carey ME, Cradock S, Dallosso HM, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K, Oliver L & on behalf of The DESMOND Collaborat (2011) Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: Results from the DESMOND trial. Psychology & Health, 26(3), 321-335.
• Kengne AP, Patel A, Marre M, Travert F, Lievre M, Zoungas S, Chalmers J, Colagiuri S, Grobbee DE, Hamet P , Heller S et al (2011) Contemporary model for cardiovascular risk prediction in people with type 2 diabetes. European Journal of Cardiovascular Prevention & Rehabilitation, 18(3), 393-398.
• Lawton J, Rankin D, Cooke DD, Clark M, Elliot J & Heller S (2011) Dose Adjustment for Normal Eating: A qualitative longitudinal exploration of the food and eating practices of type 1 diabetes patients converted to flexible intensive insulin therapy in the UK. Diabetes Research and Clinical Practice, 91(1), 87-93.
• Lloyd A, Nafees B, Barnett AH, Heller S, Ploug UJ, Lammert M & Bøgelund M (2011) Willingness to Pay for Improvements in Chronic Long-Acting Insulin Therapy in Individuals With Type 1 or Type 2 Diabetes Mellitus. Clinical Therapeutics, 33(9), 1258-1267.
• Rankin D, Heller S & Lawton J (2011) Understanding information and education gaps among people with type 1 diabetes: A qualitative investigation. Patient Education and Counseling, 83(1), 87-91.
• White WB, Bakris GL, Bergenstal RM, Cannon CP, Cushman WC, Fleck P, Heller S, Mehta C, Nissen SE, Perez A , Wilson C et al (2011) EXamination of CArdiovascular OutcoMes with AlogliptIN versus Standard of CarE in Patients with Type 2 Diabetes Mellitus and Acute Coronary Syndrome (EXAMINE). A cardiovascular safety study of the dipeptidyl peptidase 4 inhibitor alogliptin in patients with type 2 diabetes with acute coronary syndrome. American Heart Journal.
• White WB, Bakris GL, Bergenstal RM, Cannon CP, Cushman WC, Fleck P, Heller S, Mehta C, Nissen SE, Perez A , Wilson C et al (2011) EXamination of CArdiovascular OutcoMes with AlogliptIN versus Standard of CarE in Patients with Type 2 Diabetes Mellitus and Acute Coronary Syndrome (EXAMINE). American Heart Journal, 162(4), 620-626.e1.
• Heller S (2010) Commentary. Diabetic Hypoglycemia, 3(2), 17.
• Speight J, Amiel SA, Bradley C, Heller S, Oliver L, Roberts S, Rogers H, Taylor C & Thompson G (2010) Long-term biomedical and psychosocial outcomes following DAFNE (Dose Adjustment For Normal Eating) structured education to promote intensive insulin therapy in adults with sub-optimally controlled Type 1 diabetes. Diabetes Research and Clinical Practice, 89(1), 22-29.
• Ferrari GL, Marques JLB, Gandhi RA, Heller SR, Schneider FK, Tesfaye S & Gamba HR (2010) Using dynamic pupillometry as a simple screening tool to detect autonomic neuropathy in patients with diabetes: a pilot study. BIOMED ENG ONLINE, 9. View this article in WRRO
• Heller S (2010) Prospects for an artificial pancreas. Diabetic Hypoglycemia, 3(1), 1-2.
• Sheridan PJ, Marques JLB, Newman CMH, Heller SR & Clayton RH (2010) Rate-dependent measures of repolarization predict inducibility of ventricular arrhythmias. EP Europace, 12(4), 553-560.
• Heller S, Damm P, Mersebach H, Skjoth TV, Kaaja R, Hod M, Duran-Garcia S, McCance D & Mathiesen ER (2010) Hypoglycemia in Type 1 Diabetic Pregnancy: Role of preconception insulin aspart treatment in a randomized study. Diabetes Care, 33(3), 473-477. View this article in WRRO
• Zoungas S, Patel A, Chalmers J, de Galan BE, Li Q, Billot L, Woodward M, Ninomiya T, Neal B, MacMahon S , Grobbee DE et al (2010) Severe Hypoglycemia and Risks of Vascular Events and Death. New England Journal of Medicine, 363(15), 1410-1418.
• Kengne AP, Patel A, Colagiuri S, Heller S, Hamet P, Marre M, Pan CY, Zoungas S, Grobbee DE, Neal B , Chalmers J et al (2010) The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron-MR Controlled Evaluation (ADVANCE) Study. Diabetologia, 53(5), 821-831.
• Gillett M, Dallosso HM, Dixon S, Brennan A, Carey ME, Campbell MJ, Heller S, Khunti K, Skinner TC & Davies MJ (2010) Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cost effectiveness analysis. BMJ, 341(aug20 1), c4093-c4093.
• Zoungas S, De Galan BE, Ninomiya T, Grobbee D, Hamet P, Heller S, MacMahon S, Marre M, Neal B, Patel A , Woodward M et al (2009) Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial. Diabetes Care, 32(11), 2068-2074. View this article in WRRO
• de Galan BE, Zoungas S, Chalmers J, Anderson C, Dufouil C, Pillai A, Cooper M, Grobbee DE, Hackett M, Hamet P , Heller SR et al (2009) Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial. Diabetologia, 52(11), 2328-2336.
• Heller SR (2009) A Summary of the ADVANCE Trial. Diabetes Care, 32(suppl_2), S357-S361. View this article in WRRO
• Heller S, Koenen C & Bode B (2009) Comparison of insulin detemir and insulin glargine in a basal—bolus regimen, with insulin aspart as the mealtime insulin, in patients with type 1 diabetes: A 52-week, multinational, randomized, open-label, parallel-group, Treat-to-Target noninferiority trial. Clinical Therapeutics, 31(10), 2086-2097. View this article in WRRO
• Hansen MV, Pedersen-Bjergaard U, Heller SR, Wallace TM, Rasmussen ÅK, Jørgensen HV, Pramming S & Thorsteinsson B (2009) Frequency and motives of blood glucose self-monitoring in type 1 diabetes. Diabetes Research and Clinical Practice, 85(2), 183-188.
• Choudhary P, Lonnen K, Emery CJ, MacDonald IA, MacLeod KM, Amiel SA & Heller SR (2009) Comparing hormonal and symptomatic responses to experimental hypoglycaemia in insulin- and sulphonylurea-treated Type 2 diabetes. Diabetic Medicine, 26(7), 665-672.
• Cryer PE, Axelrod L, Grossman AB, Heller SR, Montori VM, Seaquist ER & Service FJ (2009) Evaluation and Management of Adult Hypoglycemic Disorders: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism, 94(3), 709-728.
• Heller SR (2009) Structured education in type 1 diabetes. The British Journal of Diabetes & Vascular Disease, 9(6), 269-272.
• Heller SR (2008) Hypoglycaemia in Type 2 diabetes. Diabetes Research and Clinical Practice, 82, S108-S111. View this article in WRRO
• Heller SR (2008) Minimizing Hypoglycemia While Maintaining Glycemic Control in Diabetes. Diabetes, 57(12), 3177-3183. View this article in WRRO
• Waller H, Eiser C, Knowles J, Rogers N, Wharmby S, Heller S, Hall C, Greenhalgh S, Tinklin T, Metcalfe C , Millard E et al (2008) Pilot study of a novel educational programme for 11-16 year olds with type 1 diabetes mellitus: the KICk-OFF course. Archives of Disease in Childhood, 93(11), 927-931.
• Robinson EJ, Marques JLB & Heller SR (2008) Can spectral analysis of heart rate variability detect subclinical autonomic dysfunction as reliably as spontaneous baroreceptor sensitivity?. DIABETOLOGIA, 51, S500-S500.
• Munir A, Choudhary P, Harrison B, Heller S & Newell-Price J (2008) Continuous glucose monitoring in patients with insulinoma. Clinical Endocrinology, 68(6), 912-918.
• Davies MJ, Heller S, Skinner TC, Campbell MJ, Carey ME, Cradock S, Dallosso HM, Daly H, Doherty Y, Eaton S , Fox C et al (2008) Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cluster randomised controlled trial. BMJ, 336(7642), 491-495. View this article in WRRO
• Khunti K, Skinner TC, Heller S, Carey ME, Dallosso HM & Davies MJ (2008) Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with Type 2 diabetes: baseline data from the DESMOND randomized controlled trial. Diabetic Medicine, 25(12), 1454-1461.
• Davies MJ, Heller S, Khunti K & Skinner TC (2008) The DESMOND educational intervention. Chronic Illness, 4(1), 38-40.
• (2008) Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes. New England Journal of Medicine, 358(24), 2560-2572.
• Ferrari GL, Marques JLB, Gandhi RA, Emery CJ, Tesfaye S, Heller SR, Schneider FK & Gamba HR (2007) An approach to the assessment of diabetic neuropathy based on dynamic pupillometry.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 557-560.
• Heller S, Kozlovski P & Kurtzhals P (2007) Insulin's 85th anniversary—An enduring medical miracle. Diabetes Research and Clinical Practice, 78(2), 149-158.
• Moustafa M, Bullock AJ, Creagh FM, Heller S, Jeffcoate W, Game F, Amery C, Tesfaye S, Ince Z, Haddow DB & MacNeil S (2007) Randomized, controlled, single-blind study on use of autologous keratinocytes on a transfer dressing to treat nonhealing diabetic ulcers. Regenerative Medicine, 2(6), 887-902.
• Heller SR (2007) Self monitoring of blood glucose in type 2 diabetes. BMJ, 335(7611), 105-106.
• (2007) Risk of hypoglycaemia in types 1 and 2 diabetes: effects of treatment modalities and their duration. Diabetologia, 50(6), 1140-1147.
• McNally PG, Dean JD, Morris AD, Wilkinson PD, Compion G & Heller SR (2007) Using Continuous Glucose Monitoring to Measure the Frequency of Low Glucose Values When Using Biphasic Insulin Aspart 30 Compared With Biphasic Human Insulin 30: A double-blind crossover study in individuals with type 2 diabetes. Diabetes Care, 30(5), 1044-1048.
• Mathiesen ER, Kinsley B, Amiel SA, Heller S, McCance D, Duran S, Bellaire S & Raben A (2007) Maternal Glycemic Control and Hypoglycemia in Type 1 Diabetic Pregnancy: A randomized trial of insulin aspart versus human insulin in 322 pregnant women. Diabetes Care, 30(4), 771-776.
• Leeds JS, Sanders DS, Mackie AD, Song SH, Creagh FM, Hardisty CA, Scott AR, Heller SR, Caddick SL & Tesfaye S (2007) A prospective study of the prevalence of gastrointestinal symptoms in patients with Type 1 diabetes and correlation with diabetes control and quality of life. DIABETIC MEDICINE, 24, 65-65.
• Glasziou P, Alexander J, Beller E & Clarke P (2007) Which health-related quality of life score? A comparison of alternative utility measures in patients with Type 2 diabetes in the ADVANCE trial. Health and Quality of Life Outcomes, 5(1), 21-21. View this article in WRRO
• Fraser R & Heller SR (2007) Gestational diabetes: aetiology and management. Obstetrics, Gynaecology & Reproductive Medicine, 17(12), 345-348.
• Ferrari GL, Marques JLB, Gandhi RA, Emery CJ, Tesfaye S, Heller SR, Schneider FK & Gamba HR (2007) An Approach to the Assessment of Diabetic Neuropathy Based on Dynamic Pupillometry. 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
• Skinner TC, Carey ME, Cradock S, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K & Oliver L (2006) Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study. Patient Education and Counseling, 64(1-3), 369-377.
• Knowles J, Waller H, Eiser C, Heller S, Roberts J, Lewis M, Wilson K, Hutchinson T, Willan M, Bavelja P , Bennet G et al (2006) The development of an innovative education curriculum for 11?16 yr old children with type 1 diabetes mellitus (T1DM). Pediatric Diabetes, 7(6), 322-328.
• Kolendorf K, Ross GP, Pavlic-Renar I, Perriello G, Philotheou A, Jendle J, Gall M-A & Heller SR (2006) Insulin detemir lowers the risk of hypoglycaemia and provides more consistent plasma glucose levels compared with NPH insulin in Type 1 diabetes. Diabetic Medicine, 23(7), 729-735.
• Heller SR & Nicholson AN (2006) Aircrew and type 1 diabetes mellitus. Aviation Space and Environmental Medicine, 77(4), 456-458.
• Alexakis C, Rodrigues M, Saatchi R, Nyongesa HO, Davies C, Ireland RH, Harris ND & Heller SR (2006) A knowledge-based electrocardiogram-monitoring system for detection of the onset of nocturnal hypoglycaemia in type 1 diabetic patients. Computers in Cardiology, 33, 5-8.
• Heller SR (2006) Hypoglycaemia in diabetes. Medicine, 34(3), 107-110.
• Heller SR & Dinneen SF (2006) Surgery in patients with diabetes. Medicine, 34(2), 80-82.
• Amiel SA, Heller SR, Macdonald IA, Schwartz SL, Klaff LJ, Ruggles JA, Weyer C, Kolterman OG & Maggs DG (2005) The effect of pramlintide on hormonal, metabolic or symptomatic responses to insulin-induced hypoglycaemia in patients with type 1 diabetes. Diabetes, Obesity and Metabolism, 7(5), 504-516.
• Heller S (2005) Home blood glucose monitoring in Type 2 diabetes. Diabetic Medicine, 22(s3), 11-13.
• Lee SP, Harris ND, Robinson RT, Davies C, Ireland R, Macdonald IA & Heller SR (2005) Effect of atenolol on QTc interval lengthening during hypoglycaemia in type 1 diabetes. Diabetologia, 48(7), 1269-1272.
• Waller H, Eiser C, Heller S, Knowles J & Price K (2005) Adolescents’ and their parents’ views on the acceptability and design of a new diabetes education programme: a focus group analysis. Child: Care, Health and Development, 31(3), 283-289.
• Heller S (2004) Thoughts of a departing Editor. Diabetic Medicine, 21(12), 1261-1262.
• Pedersen-Bjergaard U, Pramming S, Heller SR, Wallace TM, Rasmussen ÅK, Jørgensen HV, Matthews DR, Hougaard P & Thorsteinsson B (2004) Severe hypoglycaemia in 1076 adult patients with type 1 diabetes: influence of risk markers and selection. Diabetes/Metabolism Research and Reviews, 20(6), 479-486.
• Murphy NP, Ford-Adams ME, Ong KK, Harris ND, Keane SM, Davies C, Ireland RH, MacDonald IA, Knight EJ, Edge JA , Heller SR et al (2004) Prolonged cardiac repolarisation during spontaneous nocturnal hypoglycaemia in children and adolescents with type 1 diabetes. Diabetologia, 47(11), 1940-1947.
• Heller S & Kinmonth AL (2004) A clinical research network in diabetes for the UK. Diabetic Medicine, 21(10), 1061-1063.
• Weaver JU, Robertson D & Atkin SL (2004) Nateglinide alone or with metformin safely improves glycaemia to target in patients up to an age of 84. Diabetes, Obesity and Metabolism, 6(5), 344-352.
• Heise T, Heinemann L, Heller S, Weyer C, Wang Y, Strobel S, Kolterman O & Maggs D (2004) Effect of pramlintide on symptom, catecholamine, and glucagon responses to hypoglycemia in healthy subjects. Metabolism, 53(9), 1227-1232.
• Heller S (2004) Weight gain during insulin therapy in patients with type 2 diabetes mellitus. Diabetes Research and Clinical Practice, 65, S23-S27.
• Moustafa M, Simpson C, Glover M, Dawson RA, Tesfaye S, Creagh FM, Haddow D, Short R, Heller S & MacNeil S (2004) A new autologous keratinocyte dressing treatment for non-healing diabetic neuropathic foot ulcers. Diabetic Medicine, 21(7), 786-789.
• Heller SR, Colagiuri S, Vaaler S, Wolffenbuttel BHR, Koelendorf K, Friberg HH, Windfeld K & Lindholm A (2004) Hypoglycaemia with insulin aspart: a double-blind, randomised, crossover trial in subjects with Type 1 diabetes. Diabetic Medicine, 21(7), 769-775.
• Lee SP, Yeoh L, Harris ND, Davies CM, Robinson RT, Leathard A, Newman C, Macdonald IA & Heller SR (2004) Influence of Autonomic Neuropathy on QTc Interval Lengthening During Hypoglycemia in Type 1 Diabetes. Diabetes, 53(6), 1535-1542.
• Robinson RTCE, Harris ND, Ireland RH, Macdonald IA & Heller SR (2004) Changes in cardiac repolarization during clinical episodes of nocturnal hypoglycaemia in adults with Type 1 diabetes. Diabetologia, 47(2), 312-315.
• Shearer A, Bagust A, Sanderson D, Heller S & Roberts S (2004) Cost-effectiveness of flexible intensive insulin management to enable dietary freedom in people with Type 1 diabetes in the UK. Diabetic Medicine, 21(5), 460-467.
• MacNeil S, Moustafa M, Short RD, Haddow DB, Jarmalowicz M, Simpson C, Warner R, Glover M, Creagh FM, Heller S , Ralston D et al (2004) Clinical evaluation of a plasma polymer surface for culture and transfer of keratinocytes for chronic wounds. Transactions - 7th World Biomaterials Congress, 1068.
• Mumme T, Reinartz P, Wirtz D, Niethard FU, Büll U & Cremerius U (2003) Analysis of 18F-FDG uptake patterns in PET for diagnosis of septic and aseptic loosening after total hip arthroplasty. Nuklearmedizin, 42(06), 234-239.
• Heller S (2003) Insulin lispro: a useful advance in insulin therapy. Expert Opinion on Pharmacotherapy, 4(8), 1407-1416.
• Robinson RTCE, Harris ND, Ireland RH, Lee S, Newman C & Heller SR (2003) Mechanisms of Abnormal Cardiac Repolarization During Insulin-Induced Hypoglycemia. Diabetes, 52(6), 1469-1474.
• Evans AT (2003) Training in flexible intensive insulin management improved glycaemic control and quality of life in type 1 diabetes. Evidence-Based Medicine, 8(3), 80-80.
• Heller S (2003) The National Service Framework for Diabetes: a glass half empty or half full?. Diabetic Medicine, 20(3), 173-174.
• Lee S, Harris ND, Robinson RT, Yeoh L, Macdonald IA & Heller SR (2003) Effects of adrenaline and potassium on QTc interval and QT dispersion in man. European Journal of Clinical Investigation, 33(2), 93-98.
• Heller SR (2002) Cardiac arrhythmias in hypoglycaemia. Diabetes, Nutrition and Metabolism - Clinical and Experimental, 15(6), 461-467.
• DAFNE Study Group (2002) Training in flexible, intensive insulin management to enable dietary freedom in people with type 1 diabetes: dose adjustment for normal eating (DAFNE) randomised controlled trial. BMJ, 325(7367), 746-746.
• Heller SR (2002) What we know about counterregulation in Type 2 diabetes. Diabetes, Nutrition and Metabolism - Clinical and Experimental, 15(5), 372-376.
• Heller S (2002) Reducing hypoglycaemia with insulin analogues. International Journal of Obesity, 26(S3), S31-S36.
• Heller SR (2002) Abnormalities of the electrocardiogram during hypoglycaemia: The cause of the dead in bed syndrome?. International Journal of Clinical Practice, Supplement(129), 27-32.
• Clowes JA, Robinson RT, Heller SR, Eastell R & Blumsohn A (2002) Acute changes of bone turnover and PTH induced by insulin and glucose: Euglycemic and hypoglycemic hyperinsulinemic clamp studies. Journal of Clinical Endocrinology and Metabolism, 87(7), 3324-3329.
• Clowes JA (2002) Acute Changes of Bone Turnover and PTH Induced by Insulin and Glucose: Euglycemic and Hypoglycemic Hyperinsulinemic Clamp Studies. Journal of Clinical Endocrinology & Metabolism, 87(7), 3324-3329.
• Heller S (2002) Mistaken priorities in diabetes research. Diabetic Medicine, 19(4), 263-264.
• Heller SR, Amiel SA, Evans ML, Kong M-F, Macdonald IA & Peacey SR (2002) Does insulin lispro preserve the physiological defences to hypoglycaemia during intensive insulin therapy with a conventional basal bolus regimen?. Diabetes, Obesity and Metabolism, 4(2), 106-112.
• Heller S, Kurtzhals P, Verge D & Lindholm A (2002) Insulin aspart: promising early results borne out in clinical practice. Expert Opinion on Pharmacotherapy, 3(2), 183-195.
• Heller SR & Dinneen SF (2002) Surgery in Patients with Diabetes. Medicine, 30(2), 66-67.
• Heller SR (2002) Hypoglycaemia in Diabetes. Medicine, 30(2), 54-57.
• Heller SR (2002) Insulin Analogues. Current Medical Research and Opinion, 18(sup1), s40-s47.
• Heller SR (2001) New electronic horizons for Diabetic Medicine. Diabetic Medicine, 18(9), 689-689.
• Clowes JA, Robinson RT, Eagleton A, Heller SR, Eastell R & Blumsohn A (2001) Acute hypoglycemia suppresses parathyroid hormone and bone turnover markers: An insulin clamp study.. JOURNAL OF BONE AND MINERAL RESEARCH, 16, S403-S403.
• Price A, Obel O, Cresswell J, Catch I, Rutter S, Barik S, Heller SR & Weetman AP (2001) Comparison of thyroid function in pregnant and non-pregnant Asian and western Caucasian women. Clinica Chimica Acta, 308(1-2), 91-98.
• Heller S (2001) Current perspectives and future treatment options in type 2 diabetes: Proceedings of a symposium, 20-22 October 2000, Dublin, Ireland: Chairman's introduction and commentary. Practical Diabetes International, 18(SUPPL.).
• Heller SR (2000) Reflections of a new Editor. Diabetic Medicine, 17(12), 819-819.
• Lee SPC, Harris ND, Yeoh LS, Macdonald IA & Heller SR (2000) Effect of intravenous adrenaline on cardiac repolarization in healthy males - Increases in corrected QT duration occur independently of hypokalaemia. JOURNAL OF PHYSIOLOGY-LONDON, 528P, 42P-42P.
• Morris BW, Kouta S, Robinson R, MacNeil S & Heller S (2000) Chromium supplementation improves insulin resistance in patients with Type 2 diabetes mellitus. Diabetic Medicine, 17(9), 684-685.
• Pramming S, Pedersen-Bjergaard U, Heller SR, Wallace T, Rasmussen AK, Jorgensen HV, Matthews DR & Thorsteinsson B (2000) Severe hypoglycaemia in unselected patients with type 1 diabetes: A cross-sectional multicentre survey. DIABETOLOGIA, 43, A194-A194.
• Peacey SR, Robinson R, Bedford C, Harris ND, Macdonald IA, Holman RR & Heller SR (2000) Does the choice of treatment for type 2 diabetes affect the physiological response to hypoglycemia?. Diabetes Care, 23(7), 1022-1023.
• (2000) New clothes for Diabetic Medicine. Diabetic Medicine, 17(6), 413-413.
• (2000) The quality of clinical care in diabetes in Britain - could do better. Diabetic Medicine, 17(5), 335-335.
• Ireland RH, Robinson RTCE, Heller SR, Marques JLB & Harris ND (2000) Measurement of high resolution ECG QT interval during controlled euglycaemia and hypoglycaemia. Physiological Measurement, 21(2), 295-303.
• Heller SR & Robinson RTCE (2000) Hypoglycaemia and associated hypokalaemia in diabetes: mechanisms, clinical implications and prevention. Diabetes, Obesity and Metabolism, 2(2), 75-82.
• (2000) The last editor of Diabetic Medicine?. Diabetic Medicine, 17(1), 1-1.
• Jenkins RC (2000) Association of elevated insulin-like growth factor binding protein-1 with insulin resistance in hyperthyroidism. Clinical Endocrinology, 52(2), 187-187.
• Heller SR (2000) Sudden cardiac death in young people with diabetes. CME Bulletin Endocrinology and Diabetes, 3(1), 4-7.
• Heller SR, Amiel SA & Mansell P (1999) Effect of the fast-acting insulin analog lispro on the risk of nocturnal hypoglycemia during intensified insulin therapy. U.K. Lispro Study Group. Diabetes Care, 22(10), 1607-1611.
• Heller S (1999) Dead in bed. Diabetic Medicine, 16(9), 782-785.
• (1999) Sudden death in young patients with Type 1 diabetes: a consequence of disease, treatment or both?. Diabetic Medicine, 16(8), 623-625.
• Robinson RTCE, Ireland NH, Harris ND, Bedford C, Fairclough E, Hudson S & Heller SR (1999) A comparison of the metabolic and cardiac electrophysiophysiological changes during experimental and clinical hypoglycaemia.. DIABETOLOGIA, 42, A71-A71.
• Heller SR, Robinson RTCE, Harris ND, Ireland RH & Lindholm A (1999) Soluble insulin and the rapid -acting analogue insulin aspart have similar effects upon ventricular repolarization.. DIABETOLOGIA, 42, A237-A237.
• Morris BW, MacNeil S, Hardisty CA, Heller S, Burgin C & Gray TA (1999) Chromium Homeostasis in Patients with Type II (NIDDM) Diabetes. Journal of Trace Elements in Medicine and Biology, 13(1-2), 57-61.
• Heller SR (1999) Diabetic hypoglycaemia. Best Practice & Research Clinical Endocrinology & Metabolism, 13(2), 279-294.
• Dixon RM, Heller S, Harris N, Camplin DA & Grubb PA (1999) The Shindig project: some lessons in implementing the GEHR architecture. Health Informatics Journal, 5(4), 200-204.
• Heller SR & Robinson RTC (1999) Glucose Metabolism, 4-26.
• Rostami-Hodjegan A, Peacey SR, George E, Heller SR & Tucker GT (1998) Population-based modeling to demonstrate extrapancreatic effects of tolbutamide. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 274(4), E758-E771.
• Rostami-Hodjegan A, Peacey SR, George E, Heller SR & Tucker GT (1998) Population-based modeling to demonstrate extrapancreatic effects of tolbutamide. American Journal of Physiology-Endocrinology and Metabolism, 274(4), E758-E771.
• Stroud CR, Heller SR, Ward JD, Hardisty CA & Weetman AP (1997) Analysis of antibodies against components of the autonomic nervous system in diabetes mellitus. QJM, 90(9), 577-585.
• Marques JLB, George E, Peacey SR, Harris ND, Macdonald IA, Cochrane T & Heller SR (1997) Altered ventricular repolarization during hypoglycaemia in patients with diabetes. Diabetic Medicine, 14(8), 648-654.
• George E, Marques JL, Harris ND, Macdonald IA, Hardisty CA & Heller SR (1997) Preservation of Physiological Responses to Hypoglycemia 2 Days After Antecedent Hypoglycemia in Patients With IDDM. Diabetes Care, 20(8), 1293-1298.
• George E, Bedford C, Peacey SR, Hardisty CA & Heller SR (1997) Further evidence for a high incidence of nocturnal hypoglycaemia in IDDM: no effect of dose for dose transfer between human and porcine insulins. Diabetic Medicine, 14(6), 442-448.
• Dornan TL, Grenfell A, Heller SR, Morrish N, Scarpello J & Tooke J (1997) Diabetes in the Undergraduate Medical Curriculum: A Response to ‘Tomorrow's’ Doctors'. Diabetic Medicine, 14(4), 275-278.
• Peacey SR (1997) The Use of Tolbutamide-Induced Hypoglycemia to Examine the Intraislet Role of Insulin in Mediating Glucagon Release in Normal Humans. Journal of Clinical Endocrinology & Metabolism, 82(5), 1458-1461.
• Rostami-Hodjegan A, Peacey SR, George E, Heller SR & Tucker GT (1996) The insulinergic effect of tolbutamide during euglycaemic clamp in non-diabetic subjects: Pharmacokinetic-pharmacodynamic modelling. British Journal of Clinical Pharmacology, 41(5).
• Harris ND, Baykouchev SB, Marques JLB, Cochrane T, George E, Heller SR & Ward JD (1996) A portable system for monitoring physiological responses to hypoglycaemia. Journal of Medical Engineering & Technology, 20(6), 196-202.
• Apfel J, Coles C, Crace C, Cradock S, Day J, Durrant S, Elster B, Felton AM, Finn L, Hatcher T , Heller S et al (1996) Training and professional development in diabetes care. Diabetic Medicine, 13(SUPPL. 4).
• Apfel J, Coles C, Crace C, Cradock S, Day J, Durrant S, Elster B, Felton AM, Finn L, Hatcher T , Heller S et al (1996) Training and professional development in diabetes care.. Diabet Med, 13(9 Suppl 4), S65-S76.
• Marques JLB, Harris ND, Marlow S, Bedford C, Cochrane T & Heller SR (1996) Abnormalities on the ECG during spontaneous overnight hypoglycaemia in patients with type 1 diabetes. DIABETOLOGIA, 39, 824-824.
• Harris ND, Marques JLB, George E, Bedford C & Heller SR (1996) In search of a hypoglycaemic alarm. DIABETOLOGIA, 39, 832-832.
• Peacey SR, Bedford C, Marlow S, Harris N, Hardisty CA, Macdonald IA & Heller SR (1996) Impaired peripheral physiological responses to hypoglycaemia in insulin treated type II diabetes. DIABETOLOGIA, 39, 243-243.
• Heller SR, Rostamihodjegan A, Peacy SA & Tucker GT (1996) Fasting insulin predicts the acute insulinergic effect of tolbutamide, which is not related to hypoglycaemic effect.. DIABETOLOGIA, 39, 870-870.
• RostamiHodjegan A, Peacy SA, Heller SR & Tucker GT (1996) Tolbutamide enhances glucose effectiveness following acute administration in non-diabetic subjects.. DIABETOLOGIA, 39, 869-869.
• Amiel SA & Heller SR (1996) Experimentally induced hypoglycaemia. The Lancet, 348(9019), 60-61.
• Peacey SR, George E, Rostami-Hodjegan A, Bedford C, Harris N, Hardisty CA, Tucker GT, Macdonald IA & Heller SR (1996) Similar Physiological and Symptomatic Responses to Sulphonylurea and Insulin Induced Hypoglycaemia in Normal Subjects. Diabetic Medicine, 13(7), 634-641.
• Heller SR & Macdonald IA (1996) The Measurement of Cognitive Function During Acute Hypoglycaemia: Experimental Limitations and Their Effect on the Study of Hypoglycaemia Unawareness. Diabetic Medicine, 13(7), 607-615.
• Price A (1996) Asian women are at increased risk of gestational thyrotoxicosis. Journal of Clinical Endocrinology & Metabolism, 81(3), 1160-1163.
• George E, Harris N, Bedford C, Macdonald IA, Hardisty CA & Heller SR (1995) Prolonged but partial impairment of the hypoglycaemic physiological response following short-term hypoglycaemia in normal subjects. Diabetologia, 38(10), 1183-1190.
• George E, Harris N, Bedford C, Macdonald IA, Hardisty CA & Heller SR (1995) Prolonged but partial impairment of the hypoglycaemic physiological response following short-term hypoglycaemia in normal subjects. Diabetologia, 38(10), 1183-1190.
• HELLER SR, MARQUES JLB, GEORGE E, HARRIS ND & COCHRANE T (1995) QTC INTERVAL PROLONGATION DURING HYPOGLYCEMIA IN PATIENTS WITH IDDM - A POSSIBLE MECHANISM OF SUDDEN-DEATH. DIABETOLOGIA, 38, A18-A18.
• GEORGE E, MARQUES J, HARRIS N, HARDISTY CA & HELLER SR (1995) PHYSIOLOGICAL-RESPONSES TO HYPOGLYCEMIA ARE NOT REDUCED 2 DAYS AFTER ANTECEDENT HYPOGLYCEMIA IN IDDM. DIABETOLOGIA, 38, A18-A18.
• Heller S, Chapman J, McCloud J & Ward J (1995) Unreliability of reports of hypoglycaemia by diabetic patients. BMJ, 310(6977), 440-440.
• GEORGE E, PEACEY SR, BEDFORD C & HELLER SR (1994) HYPOGLYCEMIA ATTENUATES PHYSIOLOGICAL-RESPONSES TO FURTHER HYPOGLYCEMIA UP TO ONE, WEEK LATER. DIABETOLOGIA, 37, A165-A165.
• Heller S & Ward JD (1993) Neurologic consequences of hypoglycemia and pathogenic mechanisms involved in diabetic neuropathy. Current Opinion in Neurology and Neurosurgery, 6(3), 423-428.
• Heller S, Mathers N & Mackinnon M (1992) Brittle diabetes in the young. Practitioner, 236(1521), 1126-1129.
• Yudkin J, Heller SR & Tattersall R (1992) Book reviews. Diabetologia, 35(10), 1009-1010.
• Macleod AF, Boulton AJM, Owens DR, Van Rooy P, Van Gerven JMA, Macrury S, Scarpello JHB, Segers O, Heller SR, Van Der Veen EA , Sonksen PH et al (1992) A multicentre trial of the aldose-reductase inhibitor tolrestat, in patients with symptomatic diabetic peripheral neuropathy. Diabete et Metabolisme, 18(1), 14-20.
• Heller SR & Cryer PE (1991) Hypoinsulinemia is not critical to glucose recovery from hypoglycemia in humans. American Journal of Physiology-Endocrinology and Metabolism, 261(1), E41-E48.
• Heller SR & MacDonald IA (1991) Physiological disturbances in hypoglycaemia: Effect on subjective awareness. Clinical Science, 81(1), 1-9.
• Hirsch IB, Heller SR & Cryer PE (1991) Increased symptoms of hypoglycaemia in the standing position in insulin-dependent diabetes mellitus. Clinical Science, 80(6), 583-586.
• Tattersall R, Gregory R, Selby C, Kerr D & Heller S (1991) Course of brittle diabetes: 12 year follow up.. BMJ, 302(6787), 1240-1243.
• Heller SR & Cryer PE (1991) Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans. Diabetes, 40(2), 223-226.
• Heller SR & Cryer PE (1991) Reduced Neuroendocrine and Symptomatic Responses to Subsequent Hypoglycemia After 1 Episode of Hypoglycemia in Nondiabetic Humans. Diabetes, 40(2), 223-226.
• Dornan TL, Heller SR, Peck GM & Tattersal RB (1991) Double-Blind Evaluation of Efficacy and Tolerability of Metformin in NIDDM. Diabetes Care, 14(4), 342-344.
• Kerr D, MacDonald IA, Heller SR & Tattersall RB (1990) Beta-adrenoceptor blockade and hypoglycaemia. A randomised, double- blind, placebo controlled comparison of metoprolol CR, atenolol and propranolol LA in normal subjects.. British Journal of Clinical Pharmacology, 29(6), 685-693.
• Kerr D, Macdonald IA, Heller SR & Tattersall RB (1990) Alcohol causes hypoglycaemic unawareness in healthy volunteers and patients with Type 1 (insulin-dependent) diabetes. Diabetologia, 33(4), 216-221.
• Heller SR, Clarke P, Daly H, Davis I, McCulloch DK, Allison SP & Tattersall RB (1988) Group Education for Obese Patients with Type 2 Diabetes: Greater Success at Less Cost. Diabetic Medicine, 5(6), 552-556.
• Heller SR & Tattersall RB (1987) Optic Disc Swelling in Young Diabetic Patients: a Diagnostic Dilemma. Diabetic Medicine, 4(3), 260-264.
• Heller SR, Macdonald IA & Tattersall RB (1987) Counterregulation in Type 2 (non-insulin-dependent) diabetes mellitus. Normal endocrine and glycaemic responses, up to ten years after diagnosis. Diabetologia, 30(12), 924-929.
• Heller SR, Herbert M, Macdonald IA & Tattersall RB (1987) INFLUENCE OF SYMPATHETIC NERVOUS SYSTEM ON HYPOGLYCAEMIC WARNING SYMPTOMS. The Lancet, 330(8555), 359-363.
• Wilson RM (1986) Starting Insulin Treatment as an Outpatient. JAMA, 256(7), 877-877.
• Wilson RM (1986) Starting insulin treatment as an outpatient. Report of 100 consecutive patients followed up for at least one year. JAMA: The Journal of the American Medical Association, 256(7), 877-880.
• Heller SR & Hosking DJ (1986) Renal handling of calcium and sodium in metastatic and non-metastatic malignancy.. BMJ, 292(6520), 583-586.
• Hosking DJ & Heller SR (1986) Quantitation of the renal effect of calcitonin in the hypercalcaemia of malignancy. European Journal of Clinical Pharmacology, 31(1), 27-31.
• Dornan TL & Heller SR (1985) MICROALBUMINURIA AND RETINOPATHY. The Lancet, 326(8448), 212-212.
• Wilson RM, Minne P, Deverill I, Heller SR, Gelsthorpe K, Reeves WG & Tattersall RB (1985) Insulin Dependence: Problems with the Classification of 100 Consecutive Patients. Diabetic Medicine, 2(3), 167-172.
• Heller SR (1985) The chemical information system and spectral databases. Journal of Chemical Information and Modeling, 25(3), 224-231.
• Baldwin N, Scott AR, Heller SR, O'Donoghue D & Tattersall RB (1985) Vertebral and Paravertebral Sepsis in Diabetes: An Easily Missed Cause of Backache. Diabetic Medicine, 2(5), 395-397.
• Heller SR, Lowe JM, Johnson IR, O'Brien PMS, Clarke P, Symonds EM & Tattersall RB (1984) Seven Years Experience of Home Management in Pregnancy in Women with Insulin-dependent Diabetes. Diabetic Medicine, 1(3), 199-204.
• Heller SR, Fellows IW, Ogilvie AL & Atkinson M (1982) Non-steroidal anti-inflammatory drugs and benign oesophageal stricture.. BMJ, 285(6336), 167-168.
• Garden GL, Fan KS, Paterson M, Shojaee-Moradie F, Borg Inguanez M, Manoli A, Edwards V, Lee V, Frier BM, Hutchison EJ , Maher D et al () Effects of atmospheric pressure change during flight on insulin pump delivery and glycaemic control of pilots with insulin-treated diabetes: an in vitro simulation and a retrospective observational real-world study. Diabetologia.
• Holmes‐Truscott E, Broadley MM, Søholm U, Cooke DD, Hendrieckx C, Coates EJ, Heller SR & Speight J () Acceptability and psychometric properties of four scales assessing the impact of Type 2 diabetes on quality of life—Results of ‘YourSAY: Quality of Life’. Diabetic Medicine.
• Søholm U, Broadley M, Zaremba N, Divilly P, Baumann PM, Mahmoudi Z, Martine-Edith G, Mader JK, Cigler M, Brøsen JMB , Vaag A et al () The impact of hypoglycaemia on daily functioning among adults with diabetes: a prospective observational study using the Hypo-METRICS app. Diabetologia.
• Mellor J, Kuznetsov D, Heller S, Gall M-A, Rosilio M, Amiel SA, Ibberson M, McGurnaghan S, Blackbourn L, Berthon W , Salem A et al () Estimating risk of consequences following hypoglycaemia exposure using the Hypo-RESOLVE cohort: a secondary analysis of pooled data from insulin clinical trials. Diabetologia.
• Lawton J, Rankin D, Scott E, Lorencatto F, Gericke C, Heller SR & de Zoysa N () From educator to facilitator: Healthcare professionals' experiences of, and views about, delivering a type 1 diabetes structured education programme (DAFNEplus ) informed by behavioural science. Diabetic Medicine.
• Hart RI, Rankin D, Chadwick PM, de Zoysa N, Heller S, Cooke D, Elliott J & Lawton J () Sustaining the benefits of structured education: Participants' experiences of receiving structured individual support during a programme (DAFNEplus) informed by behavioural science. Diabetic Medicine.
• Mellor J, Kuznetsov D, Heller S, Gall M-A, Rosilio M, Amiel SA, Ibberson M, McGurnaghan S, Blackbourn L, Berthon W , Salem A et al () Risk factors and prediction of hypoglycaemia using the Hypo-RESOLVE cohort: a secondary analysis of pooled data from insulin clinical trials. Diabetologia.
• Carlton J, Powell PA, Broadley M, de Galan BE, Heller S, Comins J, Rosilio M, Pouwer F, Gall M-A, Child CJ , McCrimmon RJ et al () Development of a new health-related quality of life measure for people with diabetes who experience hypoglycaemia: the Hypo-RESOLVE QoL. Diabetologia.
• Zaremba N, Martine‐Edith G, Divilly P, Søholm U, Broadley M, Ali N, Abbink EJ, de Galan B, Cigler M, Mader JK , Brosen J et al () Associations of clinical, psychological, and sociodemographic characteristics and ecological momentary assessment completion in the 10‐week Hypo‐METRICS study: Hypoglycaemia MEasurements ThResholds and ImpaCtS. Diabetic Medicine.
• Arshad MF, Walkinshaw E, Solomon AL, Bernjak A, Rombach I, Little SA, Shaw JAM, Heller SR & Iqbal A () Diabetic autonomic neuropathy does not impede improvement in hypoglycaemia awareness in adults: Sub‐study results from the HypoCOMPaSS trial. Diabetic Medicine.
• Lin YK, Ye W, Rogers H, Brooks A, Toschi E, Kariyawasam D, Heller S, de Zoysa N & Amiel SA () Mitigating Severe Hypoglycemia in Users of Advanced Diabetes Technologies: Impaired Awareness of Hypoglycemia and Unhelpful Hypoglycemia Beliefs as Targets for Interventions. Diabetes Technology & Therapeutics.
• Martine-Edith G, Zaremba N, Divilly P, Søholm U, Broadley M, Baumann PM, Mahmoudi Z, Gomes M, Ali N, Abbink EJ , de Galan BE et al () Associations between hypoglycemia awareness status and symptoms of hypoglycemia among adults with type 1 or insulin-treated type 2 diabetes using the Hypo-METRICS smartphone application. Diabetes Technology & Therapeutics.
• Healey A, Soukup T, Sevdalis N, Bakolis I, Cross S, Heller SR, Brooks A, Kariyawasam D, Toschi E, Gonder‐Frederick L , Stadler M et al () Cost‐effectiveness of a Novel Hypoglycaemia Programme: The ‘HARPdoc vs BGAT’ RCT. Diabetic Medicine.
• Martine-Edith G, Divilly P, Zaremba N, Søholm U, Broadley M, Baumann PM, Mahmoudi Z, Gomes M, Ali N, Abbink EJ , de Galan BE et al () A comparison of the rates of clock-based nocturnal hypoglycemia and hypoglycemia whilst asleep among people living with diabetes: findings from the Hypo-METRICS study. Diabetes Technology & Therapeutics.
• Fabricius TW, Verhulst CEM, Kristensen PL, Holst JJ, Tack CJ, McCrimmon RJ, Heller SR, Evans ML, de Galan BE & Pedersen-Bjergaard U () Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study. Acta Diabetologica.
• Lawton J, Chadwick PM, de Zoysa N, Stanton‐Fay S, Heller SR & Rankin D () Participants' experiences of attending a structured education course (DAFNEplus) informed by behavioural science. Diabetic Medicine.
• Søholm U, Zaremba N, Broadley M, Axelsen JL, Divilly P, Martine-Edith G, Amiel SA, Mader JK, Pedersen-Bjergaard U, McCrimmon RJ , Renard E et al () Assessing the Content Validity, Acceptability, and Feasibility of the Hypo-METRICS App: Survey and Interview Study. JMIR Diabetes, 8, e42100-e42100.
• Bower P, Soiland‐Reyes C, Heller S, Wilson P, Cotterill S, French D & Sutton M () Diabetes prevention at scale: narrative review of findings and lessons from the DIPLOMA evaluation of the NHS Diabetes Prevention Programme in England. Diabetic Medicine.
• Garden GL, Shojaee-Moradie F, Hutchison E, Frier BM, Shaw K, Heller S, Koehler G, Mader JK, Maher D, Roberts G & Russell-Jones D () CONTINUOUS GLUCOSE MONITORING BY INSULIN-TREATED PILOTS FLYING COMMERCIAL AIRCRAFT WITHIN THE ARA.MED.330 DIABETES PROTOCOL: A PRELIMINARY FEASIBILITY STUDY. Diabetes Technology & Therapeutics.
• Ajjan RA, Heller SR, Everett CC, Vargas-Palacios A, Higham R, Sharples L, Gorog DA, Rogers A, Reynolds C, Fernandez C , Rodrigues P et al () Multicenter Randomized Trial of Intermittently Scanned Continuous Glucose Monitoring Versus Self-Monitoring of Blood Glucose in Individuals With Type 2 Diabetes and Recent-Onset Acute Myocardial Infarction: Results of the LIBERATES Trial. Diabetes Care.
• Carlton J, Powell P, Rowen D, Broadley M, Pouwer F, Speight J, Heller S, Gall M, Rosilio M, Child CJ , Comins J et al () Producing a preference‐based quality of life measure to quantify the impact of hypoglycaemia on people living with diabetes: a mixed‐methods research protocol. Diabetic Medicine.
• Heller S, Raposo JF, Tofé S, Hanif W, Schroner Z, Down S & Blevins T () Breaking Barriers With Basal Insulin Biosimilars in Type 2 Diabetes. Clinical Diabetes.
• Verhulst CEM, Fabricius TW, Nefs G, Kessels RPC, Pouwer F, Teerenstra S, Tack CJ, Broadley MM, Kristensen PL, McCrimmon RJ , Heller S et al () Consistent Effects of Hypoglycemia on Cognitive Function in People With or Without Diabetes. Diabetes Care.
• Verhulst CEM, Fabricius TW, Teerenstra S, Kristensen PL, Tack CJ, McCrimmon RJ, Heller S, Evans ML, Amiel SA, Pedersen-Bjergaard U & de Galan BE () Glycaemic thresholds for counterregulatory hormone and symptom responses to hypoglycaemia in people with and without type 1 diabetes: a systematic review. Diabetologia.
• Jensen MV, Broadley M, Speight J, Chatwin H, Scope A, Cantrell A, Heller S, Galan BE, Hendrieckx C & Pouwer F () The impact of hypoglycaemia in children and adolescents with type 1 diabetes on parental quality of life and related outcomes: A systematic review. Pediatric Diabetes.
• Heller SR, Geybels MS, Iqbal A, Liu L, Wagner L & Chow E () A higher non-severe hypoglycaemia rate is associated with an increased risk of subsequent severe hypoglycaemia and major adverse cardiovascular events in individuals with type 2 diabetes in the LEADER study. Diabetologia.
• Wylie TAF, Shah C, Burgess L, Robertson E, Dupont D, Swindell R, Hovorka R, Murphy HR & Heller SR () Optimising the use of technology to support people with diabetes: research recommendations from Diabetes UK’s 2019 diabetes and technology workshop. Diabetic Medicine.
• Holmes‐Truscott E, Cooke DD, Hendrieckx C, Coates EJ, Heller SR & Speight J () A comparison of the acceptability and psychometric properties of scales assessing the impact of type 1 diabetes on quality of life – Results of ‘YourSAY: Quality of Life’. Diabetic Medicine.
• Hamilton K, Stanton‐Fay SH, Chadwick PM, Lorencatto F, de Zoysa N, Gianfrancesco C, Taylor C, Coates E, Breckenridge JP, Cooke D , Heller SR et al () Sustained type 1 diabetes self‐management: Specifying the behaviours involved and their influences. Diabetic Medicine.
• Moser O, Riddell MC, Eckstein ML, Adolfsson P, Rabasa‐Lhoret R, Boom L, Gillard P, Nørgaard K, Oliver NS, Zaharieva DP , Battelino T et al () Glucose management for exercise using continuous glucose monitoring ( CGM ) and intermittently scanned CGM ( isCGM ) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes ( EASD ) and of the International Society for Pediatric and Adolescent Diabetes ( ISPAD ) endorsed by JDRF and supported by the American Diabetes Association ( ADA ). Pediatric Diabetes.
• Hendrieckx C, Gonder‐Frederick L, Heller SR, Snoek FJ & Speight J () How has psycho‐behavioural research advanced our understanding of hypoglycaemia in type 1 diabetes?. Diabetic Medicine.
• Little SA, Speight J, Leelarathna L, Walkinshaw E, Tan HK, Bowes A, Lubina-Solomon A, Chadwick TJ, Stocken DD, Brennand C , Marshall SM et al () Sustained Reduction in Severe Hypoglycemia in Adults With Type 1 Diabetes Complicated by Impaired Awareness of Hypoglycemia: 2-Year Follow-up in the HypoCOMPaSS Randomized Clinical Trial. Diabetes Care, dc172682-dc172682.
• Heller S, Lawton J, Amiel S, Cooke D, Mansell P, Brennan A, Elliott J, Boote J, Emery C, Baird W , Basarir H et al () Improving management of type 1 diabetes in the UK: the Dose Adjustment For Normal Eating (DAFNE) programme as a research test-bed. A mixed-method analysis of the barriers to and facilitators of successful diabetes self-management, a health economic analysis, a cluster randomised controlled trial of different models of delivery of an educational intervention and the potential of insulin pumps and additional educator input to improve outcomes. Programme Grants for Applied Research, 2(5), 1-188. View this article in WRRO
• Choudhary P, Geddes J, Freeman JV, Emery CJ, Heller SR & Frier BM () Frequency of biochemical hypoglycaemia in adults with Type 1 diabetes with and without impaired awareness of hypoglycaemia: no identifiable differences using continuous glucose monitoring. Diabetic Medicine, 27(6), 666-672.
• Skinner TC, Carey ME, Cradock S, Dallosso HM, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K & Oliver L () Depressive symptoms in the first year from diagnosis of Type 2 diabetes: results from the DESMOND trial. Diabetic Medicine, 27(8), 965-967.
• Skinner TC, Carey ME, Cradock S, Dallosso HM, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K & Oliver L () ‘Educator talk’ and patient change: some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial. Diabetic Medicine, 25(9), 1117-1120.
• Heller S () Editorial. Diabetic Medicine, 21(9), 961-961.
• Nyongesa HO, Alexakis C, Saatchi R, Rodrigues M, Harris ND, Heller SR, Davies C, Emery C & Ireland RH () Classification of SAECG by autoregressive modelling and neural networks. 2004 IEEE Africon. 7th Africon Conference in Africa (IEEE Cat. No.04CH37590).
• Robinson RTCE, Harris ND, Ireland RH, Lindholm A & Heller SR () Comparative effect of human soluble insulin and insulin aspart upon hypoglycaemia-induced alterations in cardiac repolarization. British Journal of Clinical Pharmacology, 55(3), 246-251.
• Garden GL, Hine JL, Mitchell SJ, Hutchison EJ, Gaffney TP, Hofmann V, Frier BM, Shaw KM, Heller SR, Koehler G , Roberts GA et al () An Evaluation of the Safety of Pilots With Insulin-Treated Diabetes in Europe Flying Commercial and Noncommercial Aircraft. Diabetes Care, dc200277-dc200277.
• O'Hara MC, Hynes L, O'Donnell M, Nery N, Byrne M, Heller SR, Dinneen SF & Irish Type 1 Diabetes Young Adult Study Group () A systematic review of interventions to improve outcomes for young adults with Type 1 diabetes.. Diabet Med. View this article in WRRO
• Dowey R, Iqbal A, Heller SR, Sabroe I & Prince LR () A Bittersweet Response to Infection in Diabetes; Targeting Neutrophils to Modify Inflammation and Improve Host Immunity. Frontiers in Immunology, 12.
• Garden GL, Frier BM, Hine JL, Hutchison EJ, Mitchell SJ, Shaw KM, Heller SR, Koehler G, Hofmann V, Gaffney TP , Maher D et al () Blood Glucose Monitoring by Insulin‐Treated Pilots of Commercial and Private Aircraft: An Analysis of Out‐of‐Range Values. Diabetes, Obesity and Metabolism.
• Jensen MV, Broadley M, Speight J, Scope A, Preston L, Heller S, de Galan BE, Pouwer F & Hendrieckx C () The impact of hypoglycaemia on the quality of life of family members of adults with type 1 or type 2 diabetes – a qualitative systematic review. Diabetic Medicine.
• Chatwin H, Broadley M, Hendrieckx C, Carlton J, Heller S, Amiel SA, Galan BE, Hermanns N, Finke‐Groene K, Speight J & Pouwer F () Unmet support needs relating to hypoglycaemia among adults with type 1 diabetes: Results of a multi‐country web‐based qualitative study. Diabetic Medicine.

Chapters

• Iqbal A, Chow EYK, Jones TW & Heller SR (2024) Hypoglycaemia in Diabetes (pp. 579-601). Wiley
• Iqbal A, Chaudhury & Heller S (2024) Chapter 49 Hypoglycemia, insulin resistance, and cardiovascular disease: A possible link, Metabolic Syndrome (pp. 597-608). Elsevier
• Iqbal A, Chaudhury T & Heller S (2024) Hypoglycemia, insulin resistance, and cardiovascular disease: A possible link, Metabolic Syndrome (pp. 597-608). Elsevier
• Chow EYK & Heller S (2022) Hypoglycaemia in Diabetes, Endocrinology and Diabetes (pp. 375-386). Springer International Publishing
• Chow EYK & Heller S (2014) Hypoglycaemia in Diabetes, Endocrinology and Diabetes (pp. 429-443). Springer New York
• Frier BM, Heller SR & McCrimmon RJ (2013) Preface In Frier B, Heller S & McCrimmon R (Ed.), Hypoglycaemia in Clinical Diabetes, (pp. x-xi). Wiley
• Chow E & Heller SR (2012) Pathophysiology of the effects of hypoglycemia on the cardiovascular system (pp. 3-8).
• Heller SR & Tattersall RB (1983) Does diabetic control matter? (pp. 553-563).
• () The Neurosciences and the Practice of Aviation Medicine CRC Press
• Iqbal A & Heller S () Clinical management of type 1 diabetes, Advanced Nutrition and Dietetics in Diabetes (pp. 60-66). John Wiley & Sons, Ltd
• Chow E, Fisher M & Heller SR () Mortality, Cardiovascular Morbidity and Possible Effects of Hypoglycaemia on Diabetic Complications, Hypoglycaemia in Clinical Diabetes (pp. 263-284). John Wiley & Sons, Ltd
• Chow E & Heller SR () Nocturnal Hypoglycaemia, Hypoglycaemia in Clinical Diabetes (pp. 96-113). John Wiley & Sons, Ltd
• Heller SR () How Should Hypoglycaemia Unawareness be Managed?, Difficult Diabetes (pp. 168-187). Blackwell Science Ltd
• Fisher M & Heller SR () Mortality, Cardiovascular Morbidity and Possible Effects of Hypoglycaemia on Diabetic Complications, Hypoglycaemia in Clinical Diabetes (pp. 265-283). John Wiley & Sons, Ltd
• Heller SR () Nocturnal Hypoglycaemia, Hypoglycaemia in Clinical Diabetes (pp. 83-99). John Wiley & Sons, Ltd

Conference proceedings papers

• SOEHOLM U, BROADLEY MM, ZAREMBA N, DIVILLY P, MARTINE-EDITH G, NEFS G, MAHMOUDI Z, MADER JK, CIGLER M, RENARD E , ABBINK EJ et al (2022) 233-OR: Impact of Nocturnal Hypoglycemia on Daily Sleep Quality, Mood, and Alertness among Adults with Type 1 Diabetes: The Hypo-METRICS (Hypoglycaemia Measurement, Thresholds, and Impacts) Study. Diabetes, Vol. 71(Supplement_1)
• Pollard D, Brennan A, Coates L & Heller S (2019) PDB65 PRETRIAL MODELLING METHODS TO JUSTIFY AND INFORM THE DESIGN OF LARGE RCTS - EXPECTED VALUE OF SAMPLE INFORMATION FOR THE DAFNEPLUS DIABETES EDUCATION CLUSTER RCT. Value in Health, Vol. 22 (pp S584-S584)
• Philis-Tsimikas A, Klonoff DC, Khunti K, Bajaj HS, Leiter LA, Tutkunkardas D, Troelsen LN, Bak BA, Heller SR & Pieber TR (2019) Reduced risk of hypoglycaemia and lower HbA(1c) with degludec compared to glargine U300 in insulin-treated patients with type 2 diabetes. DIABETOLOGIA, Vol. 62 (pp S47-S47)
• Heller SR, Hachmann-Nielsen E & Kvist K (2019) Non-severe hypoglycaemia predicts increased risk of subsequent severe events in patients with type 2 diabetes. DIABETOLOGIA, Vol. 62 (pp S418-S418)
• Gillard P, Dandona P, Mathieu C, Phillip M, Heller SR, Scheerer MF, Xu J, Thoren F, Iqbal N, Investigator D & Investigator D (2019) Analysis of patients in the dapagliflozin DEPICT-1 and-2 trials in type 1 diabetes according to HbA(1c) subgroup. DIABETOLOGIA, Vol. 62 (pp S347-S347)
• Bernjak A, Heller SR & Clayton RH (2019) Can computational modelling explain the dead in bed syndrome?. DIABETOLOGIA, Vol. 62 (pp S46-S46)
• Novodvorsky P, Oprescu A, Elliott J & Heller SR (2019) An audit on multidisciplinary team-lead 'Impaired Awareness of Hypoglycaemia' clinic: Outcomes, challenges and experience from Sheffield. DIABETIC MEDICINE, Vol. 36 (pp 79-79)
• Jamieson T, Heller SR, Ajjan RA & Kavanagh S (2019) Design and implementation of a hypoglycaemia toolkit for use in primary care settings. DIABETIC MEDICINE, Vol. 36 (pp 95-95)
• Ali Abdelhamid Y, Bernjak A, Summers M, Weinel L, Chow E, Kar P, Phillips L, Horowitz M, Heller S & Deane A (2019) Asymptomatic Hypoglycemia Is Prevalent and Associated with Cardiac Rhythm Disturbances in Survivors of Critical Illness with Insulin-Treated Type 2 Diabetes. C103. CRITICAL CARE: THE LONG WALK - ELUCIDATING OUTCOMES: DEATH, FUNCTIONAL STATUS AND COGNITION
• Jaeckel E, Heller S, Bowering K, Raskin P, Liebl A, Buchholtz K, Demissie M & Pieber TR (2018) 1,5-Anhydroglucitol korreliert bei Patienten mit Typ 1 Diabetes unabhängig vom HbA1c-Responderstatus mit der postprandialen Glucose. „Wissenschaft und klinischer Fortschritt – gemeinsam in die Zukunft“ – www.diabeteskongress.de, 9 May 2018 - 12 May 2018.
• Bernjak A, Chow E, Lee J, Iqbal A, Lubina-Solomon A, Walkinshaw E, Macdonald IA, Heller SR, Clayton RH & Sheridan PJ (2017) Pharmacological autonomic blockade during experimental hypoglycaemia exacerbates cardiac repolarisation abnormalities. DIABETOLOGIA, Vol. 60 (pp S74-S74)
• Novodvorsky P, Bernjak A, Chow E, Iqbal A, Sellors L, Williams S, Fawdry RA, Jacques RM, Sheridan PJ & Heller SR (2017) Risk of cardiac arrhythmias and electrophysiological responses during spontaneous hyperglycaemia in young people with type 1 diabetes. DIABETOLOGIA, Vol. 60 (pp S534-S534)
• Speight J, Holmes-Truscott E, Kerr D, Flanagan D, Heller SR, Evans ML & Shaw JAM (2017) Satisfaction with insulin delivery and glucose monitoring modalities among adults with long-standing Type 1 diabetes and problematic hypoglycaemia: results from the HypoCOMPaSS study. DIABETIC MEDICINE, Vol. 34 (pp 30-30)
• Holmes-Truscott E, Speight J, Kerr D, Flanagan D, Heller SR, Evans ML & Shaw JAM (2017) Sustained improvement in diabetes-specific quality of life in adults with long-standing Type 1 diabetes and problematic hypoglycaemia: two year results from the HypoCOMPaSS study. DIABETIC MEDICINE, Vol. 34 (pp 13-13)
• Russell‐Jones D, Heller SR, Buchs S, Sandberg A, Valentine WJ & Hunt B (2017) Projected long‐term outcomes in patients with type 1 diabetes treated with fast‐acting insulin aspart vs conventional insulin aspart in the UK setting. Diabetes, Obesity and Metabolism, Vol. 19(12) (pp 1773-1780) View this article in WRRO
• Lloyd AJ, Meneghini L, Kragh N, Nikolajsen A, Lewis HB & Heller SR (2016) Psychometric properties of a new scale assessing the impact of acute postprandial hyperglycaemia: the aPPHG-Q. QUALITY OF LIFE RESEARCH, Vol. 25 (pp 132-133)
• Sinclair A, Heller SR, Pratley RE, Weitgasser R, Festa A, Kiljanski J, Brusko CS, Duan R & Heine RJ (2016) Comparison of two treatment approaches in older patients with type 2 diabetes (IMPERIUM). DIABETOLOGIA, Vol. 59 (pp S395-S396)
• Korsatko S, Brunner M, Sach-Friedl S, Jensen L, Tarp M, Holst AG, Heller SR & Pieber TR (2016) Effect of once-weekly semaglutide on the counter-regulatory response to hypoglycaemia in subjects with type 2 diabetes. DIABETOLOGIA, Vol. 59 (pp S363-S364)
• Heller SR, Bergenstal R, Cannon CP, Kupfer S, Wilson C, White WB & Investigators EXAMINE (2016) Hypoglycaemia is associated with increased risk of cardiovascular events: results from the EXAMINE trial. DIABETOLOGIA, Vol. 59 (pp S44-S44)
• Kar P, Plummer MP, Giersch E, Summers MJ, Hatzinikolas S, Horowitz M, Chapman MJ, Jones KL, Heller SR & Deane A (2016) Effects of antecedent hypoglycaemia on gastric and cardiac responses to subsequent hypoglycaemia in health. DIABETOLOGIA, Vol. 59 (pp S405-S405)
• Walkinshaw E, Little SA, Bernjak A, Lubina-Solomon A, Chow E, Shaw JAM & Heller SR (2015) Cardiac autonomic regulation during experimental hypoglycaemia in type 1 diabetes with impaired awareness of hypoglycaemia. DIABETOLOGIA, Vol. 58 (pp S63-S63)
• White WB, Wilson CA, Bakris GL, Bergenstal RM, Cannon CP, Cushman WC, Fleck PR, Heller SR, Kupfer S, Mehta CR , Menon V et al (2015) Major cardiovascular outcomes in the EXAMINE trial according to ACE inhibitor use. DIABETOLOGIA, Vol. 58 (pp S395-S396)
• Tan HK, Little SA, Leelarathna L, Walkinshaw E, Lubina-Solomon A, Kerr D, Heller SR, Evans ML, Shaw JA, Flanagan D & Speight J (2015) Hypoglycaemia avoidance training improves glucose variability in Type 1 diabetes (HypoCOMPaSS Study). DIABETIC MEDICINE, Vol. 32 (pp 7-7)
• Heller SR, Mathieu C, Kapur R, Wolden ML & Zinman B (2015) Nocturnal confirmed hypoglycaemia with insulin degludec vs insulin glargine: rate ratios for different definitions. DIABETIC MEDICINE, Vol. 32 (pp 67-67)
• Speight J, Singh H, Little SA, Flanagan D, Kerr D, Evans ML, Heller SR & Shaw JA (2015) Associations with hyperglycaemia avoidance among adults with long-standing Type 1 diabetes and impaired awareness of hypoglycaemia: baseline characteristics from the HypoCOMPaSS Study. DIABETIC MEDICINE, Vol. 32 (pp 186-186)
• Sellors L, Parekh B, Bernjak A, Chow E, Sheridan P & Heller SR (2015) Effect of sleep on cardiac autonomic tone during nocturnal hypoglycaemia in adults with Type 1 diabetes. DIABETIC MEDICINE, Vol. 32 (pp 21-21)
• Walkinshaw E, Little SA, Bernjak A, Lubina-Solomon A, Chow E, Shaw JA & Heller SR (2015) Cardiac autonomic regulation during experimental hypoglycaemia in Type 1 diabetes with impaired awareness of hypoglycaemia (IAH). DIABETIC MEDICINE, Vol. 32 (pp 61-61)
• Thabit H, Elleri D, Leelarathna L, Allen J, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska M , Barnard K et al (2015) Unsupervised overnight closed loop insulin delivery during free living: analysis of randomised cross-over home studies in adults and adolescents with type 1 diabetes. The Lancet, Vol. 385 (pp S96-S96)
• Tauschmann M, Thabit H, Elleri D, Lubina-Solomon A, Stadler M, Heller SR, Amiel SA, Evans ML, Dunger DB & Hovorka R (2015) PERFORMANCE DURING UNSUPERVISED CLOSED LOOP IN CHILDREN AND ADULTS WITH TYPE 1 DIABETES: WHAT MAKES THE DIFFERENCE?. DIABETES TECHNOLOGY & THERAPEUTICS, Vol. 17 (pp A100-A101)
• Leelarathna L, Thabit H, Elleri D, Allen JM, Lubina-Solomon A, Mader JK, Benesch C, Stadler M, Pieber TR, Arnolds S , Heller SR et al (2014) Accuracy of Continuous Glucose Monitoring (CGM) under free-living conditions during three home closed loop studies. DIABETOLOGIA, Vol. 57 (pp S406-S407)
• White WB, Heller SR, Bergenstal RM, Wilson C & Oh R (2014) Effects of baseline glycaemic HbA1c on CV outcomes and blood glucose control during the EXAMINE trial in patients with type 2 diabetes and recent acute coronary syndrome. DIABETOLOGIA, Vol. 57 (pp S357-S357)
• Tauschmann M, Thabit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P , Heller SR et al (2014) Factors predictive of overnight closed loop performance during free living in children and adults with type 1 diabetes. DIABETOLOGIA, Vol. 57 (pp S414-S414)
• Heller SR, Frier BM, Herslov ML, Gundgaard J & Gough S (2014) Severe hypoglycaemia often results in hospital visits and ambulance calls regardless of insulin regimen. DIABETOLOGIA, Vol. 57 (pp S204-S204)
• Chow E, Bernjak A, Sheridan PJ & Heller SR (2014) Cardiac autonomic regulation during acute experimental hypoglycaemia in type 2 diabetes. DIABETOLOGIA, Vol. 57 (pp S260-S261)
• Habit H, Leelarathna L, Elleri D, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska ME , Heller SR et al (2014) Three to four weeks of overnight closed loop insulin delivery during free living: analysis of randomised crossover studies in adults and adolescents with type 1 diabetes. DIABETOLOGIA, Vol. 57 (pp S89-S89)
• Thabit H, Hovorka R, Walkinshaw E, Lubina-Solomon A, Stadler M, Tinati T, Heller SR, Amiel SA, Evans ML & Barnard KD (2014) Psychosocial impact of closed loop therapy for adults with Type 1 diabetes: overnight closed loop at home study. DIABETIC MEDICINE, Vol. 31 (pp 151-151)
• Chow E, Iqbal A, Bernjak A, Ajjan R & Heller SR (2014) Effect of hypoglycaemia on thrombosis and inflammation in patients with type 2 diabetes. The Lancet, Vol. 383 (pp S35-S35)
• Barnard KD, Thabit H, Walkinshaw E, Lubina-Solomon A, Stadler M, Tinati T, Heller SR, Amiel SA, Evans M & Hovorka R (2014) PSYCHOSOCIAL IMPACT OF CLOSED LOOP THERAPY - ADULTS WITH TYPE 1 DIABETES: OVERNIGHT CLOSED LOOP AT HOME STUDY. DIABETES TECHNOLOGY & THERAPEUTICS, Vol. 16 (pp A102-A102)
• Heller SR, Korsatko S, Gurban J, Jensen L, Christiansen E, Kiyomi F & Pieber TR (2013) Positive effects of liraglutide as adjunct to insulin in type 1 diabetes: glycaemic control and safety in a randomised, double blind, placebo controlled crossover trial. DIABETOLOGIA, Vol. 56 (pp S7-S8)
• Pieber TR, Deller S, Brunner M, Jensen L, Christiansen E, Kiyomi F & Heller SR (2013) Treatment with liraglutide as adjunct to insulin in type 1 diabetes; effects on counter regulatory response to hypoglycaemia: a randomised, double blind, crossover trial. DIABETOLOGIA, Vol. 56 (pp S404-S405)
• O' Hara M, Byrne M, Lawton J, Mueller U, Mueller N, Zillich F, Mansell P, Lawrence I, Heller SR, Dinneen SF , O' Shea E et al (2013) A cross country qualitative investigation of structured education programmes for adults with type 1 diabetes. DIABETOLOGIA, Vol. 56 (pp S452-S453)
• Bernjak A, Chow EYK, Walkinshaw E, Lubina-Solomon A, Sheridan PJ & Heller SR (2013) Experimental hypoglycaemia decreases cardiac vagal function for between 7 to 30 days in patients with type 2 diabetes. DIABETOLOGIA, Vol. 56 (pp S243-S243)
• Chow EYK, Iqbal A, Phoenix F, Heller SR & Ajjan R (2013) Hypoglycaemia promotes thrombosis and inflammation for at least one week in patients with type 2 diabetes. DIABETOLOGIA, Vol. 56 (pp S243-S243)
• Choudhary P, Davies C, Emery CJ & Heller SR (2013) Do high fasting glucose levels suggest nocturnal hypoglycaemia? The Somogyi effect-more fiction than fact?. Diabetic Medicine, Vol. 30(8) (pp 914-917)
• Heller SR, Pieber T, Korsatko S, Kohler G, Deller S, Bock G, Zahiragic S, Mader J, Roepstorff C, Rasmussen S & Haahr H (2011) A higher counter-regulatory hormone response is seen with insulin degludec than insulin glargine in response to induced hypoglycaemia in type 1 diabetes. DIABETOLOGIA, Vol. 54 (pp S261-S261)
• Russell-Jones DL, Francisco AO, Pei H & Heller SR (2011) Basal-bolus therapy with insulin degludec improves long-term glycaemic control with less nocturnal hypoglycaemia compared with insulin. DIABETOLOGIA, Vol. 54 (pp S425-S425)
• Heller S (2011) Impaired awareness of hypoglycemia: Commentary. Diabetic Hypoglycemia, Vol. 3(3) (pp 9)
• Kumareswaran K, Elleri D, Allen JM, Harris J, Xing D, Kollman C, Nodale M, Murphy HR, Amiel SA, Heller SR , Wilinska ME et al (2011) Meta-Analysis of Overnight Closed-Loop Randomized Studies in Children and Adults with Type 1 Diabetes: The Cambridge Cohort. Journal of Diabetes Science and Technology, Vol. 5(6) (pp 1352-1362)
• Heller S (2010) Hypoglycemia and clinical islet transplantation. Diabetic Hypoglycemia, Vol. 3(2) (pp 11-12)
• De Galan BE, Zoungas S, Patel A, Li Q, Billot L, Woodward M, Chalmers J, Neal B, MacMahon S, Grobbee D & Heller SR (2010) Nature of association between severe hypoglycaemia and risks of vascular events and death in ADVANCE. DIABETOLOGIA, Vol. 53
• Kumareswaran K, Harris J, Elleri D, Allen JM, Nodale M, Wilinska ME, Dunger DB, Amiel SA, Heller SR, Evans ML & Hovorka R (2010) Overnight closed-loop glucose control following consumption of alcohol in adults with type 1 diabetes. DIABETOLOGIA, Vol. 53 (pp S25-S26)
• Heller S (2007) Targeting acute hyperglycaemia in clinical practice. Diabetes Research and Clinical Practice, Vol. 78(3) (pp S40-S46) View this article in WRRO
• Choudhary P, Emery CJ & Heller SR (2007) Do high fasting glucose levels suggest nocturnal hypoglycaemia? The Somogyi effect - fact or fiction?. DIABETOLOGIA, Vol. 50 (pp S335-S336)
• Hansen MV, Pedersen-Bjergaard U, Heller SR, Wallace TM, Rasmussen AK, Jorgensen HV, Matthews DR, Hougaard P, Pramming S & Thorsteinsson B (2006) Frequency and motives of blood glucose self-monitoring in type I diabetes: association with glycaemic control, complications, and patient characteristics. DIABETOLOGIA, Vol. 49 (pp 494-494)
• Heller SR, Mathiesen E, Kinsley B, McCance D, Duran S, Bellaire S & Raben A (2006) Maternal hypoglycaemia and glycaemic control in pregnancy: a randomised trial comparing insulin aspart with human insulin in 322 subjects with type 1 diabetes. DIABETOLOGIA, Vol. 49 (pp 576-577)
• Choudhary P, Davies CM, Emery CJ, Freeman JV & Heller SR (2006) Sensitivity and specificity of CGMS for identifying clinially relevant symptomatic hypoglycaemia. DIABETOLOGIA, Vol. 49 (pp 507-508)
• Ashwell SG, Amiel SA, Bilous RW, Dashora U, Heller SR, Hepburn DA, Shutler SD, Stephens JW & Home PD (2006) Improved glycaemic control with insulin glargine plus insulin lispro: a multicentre, randomized, cross-over trial in people with Type 1 diabetes. Diabetic Medicine, Vol. 23(3) (pp 285-292)
• Alexakis C, Nyongesa HO, Saatchi R, Harris ND, Davies C, Emery C, Ireland RH & Heller SR (2003) Feature extraction and classification of electrocardiogram (ECG) signals related to hypoglycaemia. Computers in Cardiology, 2003, 24 September 2003 - 24 September 2003.
• Lee SP, Robinson RT, Harris ND, Davies CM, Cunningham M, Hudson S, Macdonald IA & Heller SR (2002) Effect of atenolol on QTc interval lengthening during hypoglycaemia in Type 1 diabetes. DIABETOLOGIA, Vol. 45 (pp A78-A78)
• RostamiHodjegan A, Peacey SR, Heller SR & Tucker GT (1996) A pharmacokinetic-pharmacodynamic model to explain the biphasic insulinergic effect of tolbutamide and the suppressive role of lowering blood glucose on this effect. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Vol. 42(5) (pp P675-P676)
• Kruger J, Brennan A, Thokala P, Fitzgerald P & Heller S () Incorporating psychosocial characteristics in cost-effectiveness modelling of Type 1 diabetes
• Harris ND, Ireland RH, Marques JLB, Hudson S, Davies C, Lee S, Robinson RT & Heller SR () Can changes in QT interval be used to predict the onset of hypoglycemia in type 1 diabetes?. Computers in Cardiology 2000. Vol.27 (Cat. 00CH37163)
• Ireland RH, Robinson RTCE, Heller SR & Harris ND () QT measurement for TU fused ECG morphology as exhibited during hypoglycaemia. Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)

Reports

• Heller S, Darpö B, Mitchell MI, Linnebjerg H, Leishman DJ, Mehrotra N, Zhu H, Koerner J, Fiszman ML, Balakrishnan S , Xiao S et al (2015) Considerations for assessing the potential effects of antidiabetes drugs on cardiac ventricular repolarization: A report from the Cardiac Safety Research Consortium
• Seaquist ER, Anderson J, Childs B, Cryer P, Dagogo-Jack S, Fish L, Heller SR, Rodriguez H, Rosenzweig J & Vigersky R (2013) Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society View this article in WRRO
• Seaquist ER, Anderson J, Childs B, Cryer P, Dagogo-Jack S, Fish L, Heller SR, Rodriguez H, Rosenzweig J & Vigersky R (2013) Hypoglycemia and Diabetes: A Report of a Workgroup of the American Diabetes Association and The Endocrine Society
• Forbes A, While A, Griffiths P, Ismail K & Heller S (2011) Organizing and delivering diabetes education and self-care support: Findings of scoping project

Posters

• Basarir H, Kruger J, Brennan A, Thokala P, Jacques R, Dixon S, Elliott J, Heller S & Mansell P The Cost-Effectiveness of 5-week versus 1-week DAFNE Structured Education in Type 1 Diabetes: A Preliminary Evaluation Using the Sheffield Type 1 Diabetes Policy Model (Diabetes UK Professional Conference 13-15 March 2013).
• Kruger J, Brennan A, Thokala P, Basarir H & Heller S The Cost-Effectiveness of Dose Adjustment For Normal Eating (DAFNE) Structured Education in Type 1 Diabetes: An Update using the Sheffield Type 1 Diabetes Policy Model (Diabetes UK Professional Conference 13-15 March 2013).

Other

• Carlton J, Leaviss J, Pouwer F, Hendrieckx C, Broadley MM, Clowes M, McCrimmon RJ, Heller SR & Speight J (2022) Correction to: The suitability of patient-reported outcome measures used to assess the impact of hypoglycaemia on quality of life in people with diabetes: a systematic review using COSMIN methods.. Diabetologia.
• Campbell M, Heller SR & Jacques RM (2018) Response to Comment on Novodvorsky et al. Diurnal Differences in Risk of Cardiac Arrhythmias During Spontaneous Hypoglycemia in Young People With Type 1 Diabetes. Diabetes Care 2017;40:655–662. Diabetes Care, 41(4), e65-e66.
• Little SA, Leelarathna L, Walkinshaw E, Kai Tan H, Chapple O, Lubina-Solomon A, Chadwick TJ, Barendse S, Stocken DD, Brennand C , Marshall SM et al (2014) Response to Comment on Little et al. Recovery of Hypoglycemia Awareness in Long-standing Type 1 Diabetes: A Multicenter 2 × 2 Factorial Randomized Controlled Trial Comparing Insulin Pump With Multiple Daily Injections and Continuous With Conventional Glucose Self-monitoring (HypoCOMPaSS). Diabetes Care 2014;37:2114–2122. Diabetes Care, 37(12), e272-e273.
• Hattersley AT, Marcovecchio ML, Chiarelli F, Silverstein J, Heller S, Damm P, Mathiesen ER, Zinman B & Sinclair A (2014) Lifecourse: management of type 1 diabetes. The Lancet Diabetes & Endocrinology, 2(3), 194-195.
• Heller SR (2014) Self-monitoring of blood glucose: a promise still unfulfilled?. Diabetologia, 57(5), 847-849.
• Barnard KD, Campbell MJ, Emery C, Young AJ & Heller S (2012) How to reduce the risk of failing to reach recruitment targets: lessons learnt from a pump pilot trial. Diabetic Medicine, 29(12), 1600-1601.
• Heller S, McCance DR, Moghissi E, Nazeri A & Kordonouri O (2012) Diversity in diabetes: the role of insulin aspart. Diabetes/Metabolism Research and Reviews, 28(1), 50-61.
• Elliott J & Heller S (2011) Hypoglycaemia unawareness. Practical Diabetes International, 28(5), 227-232.
• Heller SR (2011) Hypoglycaemia: Its pathophysiology in insulin treated diabetes and hypoglycaemia unawareness. The British Journal of Diabetes & Vascular Disease, 11(1_suppl), 6-9.
• Heller S (2010) Hypoglycaemia in diabetes. Medicine, 38(12), 671-675.
• Heller S (2010) Self-destructive behavior - A case of recurrent severe hypoglycemia. Diabetic Hypoglycemia, 2(3), 17-18.

Preprints

• Breckenridge J, Gossage-Worrall R, Chadwick P, de Zoysa N, Elliott J, Gianfrancesco C, Hamilton K, Heller S, Lawton J, Rankin D , Stanton-Fay S et al (2024) The collaborative working group method for pre-trial knowledge mobilisation: a qualitative evaluation of a structured process for iteratively refining a complex intervention (DAFNEplus), Research Square Platform LLC.
• Leavy OC, Russell RJ, Harrison EM, Lone NI, Kerr S, Docherty AB, Sheikh A, Richardson M, Elneima O, Greening NJ , Harris VC et al (2023) One year health outcomes associated with systemic corticosteroids for COVID-19: a longitudinal cohort study, Cold Spring Harbor Laboratory.
• Elneima O, McAuley HJC, Leavy OC, Chalmers JD, Horsley A, Ho L-P, Marks M, Poinasamy K, Raman B, Shikotra A , Singapuri A et al (2023) Cohort Profile: Post-hospitalisation COVID-19 study (PHOSP-COVID), Cold Spring Harbor Laboratory.
• Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB, Lone NI, Leavy OC , Daines L et al () Physical, cognitive and mental health impacts of COVID-19 following hospitalisation – a multi-centre prospective cohort study, Cold Spring Harbor Laboratory.