Professor James Catto
MB ChB PhD FRCS(Urol)
Clinical Medicine, School of Medicine and Population Health
Professor of Urology
+44 114 215 9002
Full contact details
Clinical Medicine, School of Medicine and Population Health
GU19, G Floor
The Medical School
Beech Hill Road
Sheffield
S10 2RX
- Profile
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For enquiries please contact - ClinMed-Operational@sheffield.ac.uk
James Catto is NIHR Research Professor, Professor of Urology at the University of Sheffield and an Honorary Consultant Urological Surgeon at Sheffield Teaching Hospitals NHS Trust. He holds posts as an Honorary Senior Clinical Research fellow at the University of Oxford and Honorary Clinical Professor, Division of Surgery & Interventional Science, University College London. He qualified from Leeds University in 1994 and trained in York and Sheffield, UK before a fellowship in Brisbane, Australia.
James obtained a PhD in 2004 and runs a research team investigating the biology and management of urological cancers. He was awarded the European Association of Urology Best Thesis prize and the Bard Medal from BAUS for his PhD studies. In 2007 he was EAU-AUA exchange fellow with visits to the Johns Hopkins Medical School, The University of Chicago, Loyola University and The University of California, San Francisco. In 2010, he was awarded the Crystal Matula by the EAU, the Astellas Education Foundation award in 2011 and the Golden Telescope by BAUS in 2014.
James has raised over £26 million in peer-reviewed funding, published more than 300 primary research manuscripts, and has more than 30,000 citations on Google and an H factor of 72 on Scopus. His research funding includes a NIHR Research Professorship, a GSK Clinician Scientist fellowship, an MRC Clinical Research Fellowship, and grants from NIHR/MRC, The Wellcome Trust, CRUK, European Union, Royal College of Surgeons, The Urological Foundation and Yorkshire Cancer Research.
James is Editor In Chief of European Urology (2019 Impact factor 18.728). Please see the European Urology website for further details.
- Research interests
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James leads on Urology research, encompassing NIHR Clinical Lecturers, NIHR ACFs, post-docs, technicians, research nurses and PhD students. The team research the translational application of molecular biology to urological malignancies, in particular Bladder and Prostate Cancer, and partake in clinical trials focused on improving the care of patients with these cancers. James's particular interest is in the epigenetic alterations seen within these tumours.
James is also lead for The University of Sheffield’s Cancer Research program. This multimodal data-driven patient-focussed program aims to improve survival for many common cancers across Yorkshire and create world leading expertise within Sheffield.
Current projects
James is currently Chief Investigator for i). GUSTO - Genotype of Urothelial cancer: Stratified Treatment and Oncological outcomes: Phase 2 study (funded by the MRC/NIHR), ii). iROC - A multicentre randomised controlled trial to compare the efficacy of Robotically Assisted Radical Cystectomy and intracorporeal urinary diversion with Open Radical Cystectomy in patients with bladder cancer (Funded by TUF), iii). YorkSure - Early detection of bladder cancer in Yorkshire: Feasibility assessments for implementing a targeted study in populations with high disease specific mortality risk (Funded by Yorkshire Cancer Research), iv). FINESSE - Increasing compliance with Active surveillance: A randomised trial evaluating the role of Finasteride (Funded by Yorkshire Cancer Research), v). Improving the outcomes from Bladder Cancer through the application of genomic stratification and development of novel agents (NIHR Research Professorship) and vi). Life and Bladder Cancer: The Yorkshire Cancer Research Bladder Cancer Patient Reported Outcomes Survey. (Funded by Yorkshire Cancer Research).
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Effect of robot-assisted radical cystectomy with intracorporeal urinary diversion vs open radical cystectomy on 90-day morbidity and mortality among patients with bladder cancer : a randomized clinical trial. JAMA. View this article in WRRO
- Addition of nintedanib or placebo to neoadjuvant gemcitabine and cisplatin in locally advanced muscle-invasive bladder cancer (NEOBLADE) : a double-blind, randomised, phase 2 trial. The Lancet Oncology, 23(5), 650-658. View this article in WRRO
- Comparing an Imaging-guided Pathway with the Standard Pathway for Staging Muscle-invasive Bladder Cancer: Preliminary Data from the BladderPath Study. European Urology.
- Quality of life after bladder cancer: a cross-sectional survey of patient-reported outcomes. European Urology. View this article in WRRO
- Phase I trial of DNA methyltransferase inhibitor guadecitabine combined with cisplatin and gemcitabine for solid malignancies including urothelial carcinoma (SPIRE). Clinical Cancer Research. View this article in WRRO
- Radical cystectomy against intravesical BCG for high-risk high-grade nonmuscle invasive bladder cancer: results from the randomized controlled BRAVO-feasibility study. Journal of Clinical Oncology. View this article in WRRO
- Occupational bladder cancer: A cross section survey of previous employments, tasks and exposures matched to cancer phenotypes. PLoS ONE, 15(10). View this article in WRRO
- Reporting Radical Cystectomy Outcomes Following Implementation of Enhanced Recovery After Surgery Protocols: A Systematic Review and Individual Patient Data Meta-analysis. European Urology, 78(5), 719-730.
- Safety and immunogenicity of novel 5T4 viral vectored vaccination regimens in early stage prostate cancer: a phase I clinical trial. Journal for ImmunoTherapy of Cancer, 8(1), e000928-e000928.
- Risks from Deferring Treatment for Genitourinary Cancers: A Collaborative Review to Aid Triage and Management During the COVID-19 Pandemic. European Urology, 78(1), 29-42.
- Adjuvant chemotherapy in upper tract urothelial carcinoma (the POUT trial): a phase 3, open-label, randomised controlled trial. The Lancet, 395(10232), 1268-1277. View this article in WRRO
- CALIBER - A phase II randomised feasibility trial of chemoablation with mitomycin versus surgical management in low risk non-muscle invasive bladder cancer. BJU International. View this article in WRRO
- Long term survival after radical cystectomy with respect to centralisation: Outcomes from 1110 patients treated at a single high-volume centre. European Urology Supplements, 18(1), e1134-e1134.
- Quality of life in men living with advanced and localised prostate cancer in the UK: a population-based study. The Lancet Oncology, 20(3), 436-447. View this article in WRRO
- Epidemiology of Bladder Cancer: A Systematic Review and Contemporary Update of Risk Factors in 2018. European Urology. View this article in WRRO
- Multiparametric Magnetic Resonance Imaging for Bladder Cancer: Development of VI-RADS (Vesical Imaging-Reporting And Data System). European Urology, 74(3), 294-306. View this article in WRRO
- Multidomain Quantitative Recovery Following Radical Cystectomy for Patients Within the Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion Versus Open Radical Cystectomy Randomised Controlled Trial: The First 30 Patients. European Urology, 74(4), 531-534.
- Prospective Implementation of Enhanced Recovery After Surgery Protocols to Radical Cystectomy. European Urology, 73(3), 363-371. View this article in WRRO
- Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer. Cell, 171(3), 540-556.e25.
- E-cigarettes and Urologic Health: A Collaborative Review of Toxicology, Epidemiology, and Potential Risks. European Urology, 71(6), 915-923.
- 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer. New England Journal of Medicine, 375(15), 1415-1424. View this article in WRRO
- Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer. New England Journal of Medicine, 375(15), 1425-1437. View this article in WRRO
- The Role of Tobacco Smoke in Bladder and Kidney Carcinogenesis: A Comparison of Exposures and Meta-analysis of Incidence and Mortality Risks. European Urology, 70(3), 458-466. View this article in WRRO
- The contemporary landscape of occupational bladder cancer within the United Kingdom: a meta-analysis of risks over the last 80 years. BJU International. View this article in WRRO
- Contemporary Occupational Carcinogen Exposure and Bladder Cancer. JAMA Oncology, 1(9), 1282-1290. View this article in WRRO
All publications
Books
- Preface.
- Basic Urological Sciences. CRC Press.
Journal articles
- FGFR Inhibition in Urothelial Carcinoma. European Urology.
- LBA5 A randomized phase III trial of neoadjuvant durvalumab plus chemotherapy followed by radical cystectomy and adjuvant durvalumab in muscle-invasive bladder cancer (NIAGARA). Annals of Oncology, 35, S1271-S1271.
- A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts. The Lancet Digital Health, 6(7), e507-e519.
- The psychosocial impact of prostate cancer screening for BRCA1 and BRCA2 carriers. BJU International, 134(3), 484-500.
- Use of gene expression patterns to identify unique molecular subtypes in muscle invasive bladder cancer: GUSTO.. Journal of Clinical Oncology, 42(16_suppl), TPS4621-TPS4621.
- Decision Regret Regarding Treatment Choices 1 Year After a New Diagnosis of Bladder Cancer. European Urology.
- PD36-04 REMOTE DIGITAL SURVEILLANCE AND MACHINE LEARNING MODELLING TO PREDICT SURVIVAL FOLLOWING RADICAL CYSTECTOMY FOR BLADDER CANCER—A SECONDARY OUTCOME ANALYSIS OF THE IROC TRIAL. Journal of Urology, 211(5S).
- Digital remote monitoring and Machine Learning (ML) modeling to predict survival following radical cystectomy for bladder cancer – a secondary outcome analysis of the iROC trial. European Urology, 85, S929-S930.
- SunRISe-3: TAR-200 plus cetrelimab or TAR-200 versus intravesical Bacillus Calmette–Guérin in patients with BCG-naive high-risk non–muscle-invasive bladder cancer. European Urology, 85, S1505-S1505.
- Clinical Application of Bladder MRI and Vesical Imaging-Reporting And Data System. European Urology, 85, S1874-S1875.
- UPDATED EFFICACY AND SAFETY OF ORAL ERDAFITINIB IN PATIENTS WITH BACILLUS CALMETTE-GUÉRIN–UNRESPONSIVE, HIGH-RISK NON-MUSCLE–INVASIVE BLADDER CANCER WITH FGFR3/2 ALTERATIONS IN THOR-2 COHORT 2. Urologic Oncology: Seminars and Original Investigations, 42, S53-S53.
- Gene of the month: the uroplakins. Journal of Clinical Pathology, 77(5), 291-296.
- Verification of molecular subtyping of bladder cancer in the GUSTO clinical trial. The Journal of Pathology: Clinical Research, 10(2). View this article in WRRO
- Thromboembolic events associated with neoadjuvant chemotherapy for muscle invasive cancer of the bladder.. Journal of Clinical Oncology, 42(4_suppl), 586-586.
- Real world outcomes for maintenance avelumab treatment in locally advanced/metastatic urothelial cancer after platinum-based chemotherapy.. Journal of Clinical Oncology, 42(4_suppl), 584-584.
- INVEST: A phase Ib window of opportunity study of atezolizumab administered either intravesically or direct tumour injection in patients with bladder cancer prior to radical cystectomy.. Journal of Clinical Oncology, 42(4_suppl), TPS710-TPS710.
- Interruptions in bladder cancer care during the COVID-19 public health emergency. Urologic Oncology: Seminars and Original Investigations.
- Boosting and broadening recruitment to UK cancer trials: towards a blueprint for action. BMJ Oncology, 2(1), e000092-e000092.
- Digital Tracking of Patients Undergoing Radical Cystectomy for Bladder Cancer: Daily Step Counts Before and After Surgery Within the iROC Randomised Controlled Trial. European Urology Oncology.
- Erdafitinib in BCG-treated high-risk non-muscle-invasive bladder cancer. Annals of Oncology.
- LBA102 THOR-2 cohort 1: Results of erdafitinib (ERDA) vs intravesical chemotherapy (chemo) in patients (pts) with high-risk non–muscle-invasive bladder cancer (HR NMIBC) with select fibroblast growth factor receptor alterations (FGFRALT) who received prior bacillus calmette-guérin (BCG) treatment. Annals of Oncology, 34, S1341-S1342.
- 2407TiP SunRISe-3: TAR-200 plus cetrelimab (CET) or TAR-200 versus intravesical bacillus Calmette-Guérin (BCG) in patients (pts) with BCG-naive high-risk non-muscle-invasive bladder cancer (HR NMIBC). Annals of Oncology, 34, S1224-S1224.
- Protocol for the YORKSURe prospective multistage study testing the feasibility for early detection of bladder cancer in populations with high disease-specific mortality risk. BMJ Open, 13(9), e076612-e076612.
- Corrigendum to “Robot-assisted Radical Cystectomy Versus Open Radical Cystectomy: A Systematic Review and Meta-analysis of Perioperative, Oncological, and Quality of Life Outcomes Using Randomized Controlled Trials” [Eur Urol. 2023;84:393–405]. European Urology, 84(4), e98-e99.
- Cardiopulmonary exercise testing of patients with metastatic castrate-resistant prostate cancer as screening for vigorous exercise medicine prescription.. JCO Global Oncology, 9(Supplement_1), 80-80.
- Cost-effectiveness of robot-assisted radical cystectomy vs open radical cystectomy for patients with bladder cancer. JAMA Network Open, 6(6). View this article in WRRO
- Analysis of the distal urinary tract in larval and adult zebrafish reveals homology to the human system. Disease Models & Mechanisms, dmm.050110.
- Epidemiology of Bladder Cancer in 2023: A Systematic Review of Risk Factors. European Urology, 84(2), 176-190.
- Robot-assisted Radical Cystectomy Versus Open Radical Cystectomy: A Systematic Review and Meta-analysis of Perioperative, Oncological, and Quality of Life Outcomes Using Randomized Controlled Trials. European Urology, 84(4), 393-405.
- Lifestyle Factors in Patients with Bladder Cancer: A Contemporary Picture of Tobacco Smoking, Electronic Cigarette Use, Body Mass Index, and Levels of Physical Activity. European Urology Focus.
- PD36-12 MEASURING OBJECTIVE RECOVERY OF ACTIVITY LEVELS USING WEARABLE DEVICES FOLLOWING OPEN VS INTRACORPOREAL ROBOTIC CYSTECTOMY: SECONDARY OUTCOMES ANALYSIS OF THE IROC RANDOMIZED TRIAL. Journal of Urology, 209(Supplement 4).
- An Association Study of Germline Variants in Bladder Cancer-Related Genes with the Prognosis of Non-Muscle Invasive Bladder Cancer. Bladder Cancer, 9(1), 59-71.
- Patient-Reported Outcomes 12 Years after Localized Prostate Cancer Treatment. NEJM Evidence, 2(4).
- Critical appraisal of decision models used for the economic evaluation of bladder cancer screening and diagnosis: a systematic review. PharmacoEconomics, 41(6), 633-650. View this article in WRRO
- Protocol for the TRANSLATE prospective, multicentre, randomised clinical trial of prostate biopsy technique. BJU International.
- DASL-HiCaP: A randomized, phase 3, double-blind trial of darolutamide with androgen-deprivation therapy and definitive or salvage radiation for localized very high-risk prostate cancer.. Journal of Clinical Oncology, 41(6_suppl), TPS396-TPS396.
- Study EV-104: Phase 1 study of intravesical enfortumab vedotin for treatment of patients with non-muscle invasive bladder cancer (NMIBC)—Trial in progress.. Journal of Clinical Oncology, 41(6_suppl), TPS582-TPS582.
- Phase 2 study of the efficacy and safety of erdafitinib in patients (pts) with bacillus Calmette-Guérin (BCG)-unresponsive, high-risk non–muscle-invasive bladder cancer (HR-NMIBC) with FGFR3/2 alterations (alt) in THOR-2: Cohort 2 interim analysis results.. Journal of Clinical Oncology, 41(6_suppl), 503-503.
- Elicitation of health state utilities associated with progression from Bacillus Calmette-Guerin (BCG) unresponsive Non-muscle Invasive Bladder Cancer (NMIBC). PharmacoEconomics - Open.
- Comparing objective recovery of activity levels using wearable devices in open vs. intracorporeal robotic cystectomy: An analysis of the secondary outcomes of the iROC randomized trial. European Urology, 83, S219-S220.
- Patient Preferences for Treatment of Bacillus Calmette-Guérin–unresponsive Non–muscle-invasive Bladder Cancer: A Cross-country Choice Experiment. European Urology Open Science, 49, 92-99.
- Association Between Antibiotic Prophylaxis Before Cystectomy or Stent Removal and Infection Complications: A Systematic Review. European Urology Focus, 9(4), 631-636.
- The current use of the EORTC QLQ-NMIBC24 and QLQ-BLM30 questionnaires for the assessment of health-related quality of life in bladder cancer patients: a systematic review. Quality of Life Research, 32(8), 2127-2135.
- Re. Effect of Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients with Bladder Cancer: A Randomized Clinical Trial. European Urology, 83(1), 90-91.
- Hyperthermic intravesical chemotherapy with mitomycin‐C for the treatment of high‐risk non‐muscle‐invasive bladder cancer patients. BJUI Compass. View this article in WRRO
- Effect of Robot-Assisted Radical Cystectomy vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer—Reply. JAMA, 328(12), 1258-1258.
- Monkeypox and the Urologist: Playing an Important Role in This Emerging Global Outbreak. European Urology.
- Reply to Bernardo Rocco and Maria Chiara Sighinolfi’s Letter to the Editor re: James W.F. Catto, Pramit Khetrapal, Federico Ricciardi, et al. Effect of Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients with Bladder Cancer: A Randomized Clinical Trial. JAMA 2022;327:2092–103. European Urology.
- 1733MO First results from BladderPath: A randomised trial of MRI versus cystoscopic staging for newly diagnosed bladder cancer. Annals of Oncology, 33, S1330-S1330.
- Updates on bladder, kidney and prostate cancers. BJU International, 130(3), 275-276.
- Reply to Andreas Skolarikos’s Words of Wisdom re: Effect of Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients with Bladder Cancer: A Randomized Clinical Trial. Eur Urol. In press. European Urology.
- Sexual activity, function and dysfunction after a diagnosis of bladder cancer. The Journal of Sexual Medicine, 19(9), 1431-1441. View this article in WRRO
- Social deprivation and bladder cancer: cause or effect for disparities in survival for affected women. BJU International, 130(3), 301-302.
- P7 Elicitation of Health State Utilities Associated Progression from BCG-Unresponsive Non-Muscle Invasive Bladder Cancer (NMIBC) Health States. Value in Health, 25(7), S288-S288.
- Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study. American Journal of Obstetrics and Gynecology, 227(5), 735.e1-735.e25.
- Race reporting and disparities regarding clinical trials in bladder cancer: a systematic review. Cancer Causes & Control, 33(8), 1071-1081.
- DASL-HiCaP: Darolutamide augments standard therapy for localized very high-risk cancer of the prostate (ANZUP1801)—A randomized phase 3, double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation.. Journal of Clinical Oncology, 40(16_suppl), TPS5103-TPS5103.
- Case of the month from the University of Sheffield,
UK : Expediting definitive treatment in patients with invasive bladder cancer: anMRI ‐guided pathway. BJU International, 129(6), 691-694. - Effect of robot-assisted radical cystectomy with intracorporeal urinary diversion vs open radical cystectomy on 90-day morbidity and mortality among patients with bladder cancer : a randomized clinical trial. JAMA. View this article in WRRO
- Functional and quality of life outcomes of localised prostate cancer treatments (Prostate Testing for Cancer and Treatment [ProtecT] study). BJU International. View this article in WRRO
- Reply to Benjamin Davies, Keith Kowalczyk RE: Zachary Klaassen, Emily Vertosick, Andrew J. Vickers, et al. Optimal Dissemination of Scientific Manuscripts via Social Media: A Prospective Trial Comparing Visual Abstracts Versus Key Figures in Consecutive Original Manuscripts. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2022.01.041. European Urology.
- Addition of nintedanib or placebo to neoadjuvant gemcitabine and cisplatin in locally advanced muscle-invasive bladder cancer (NEOBLADE) : a double-blind, randomised, phase 2 trial. The Lancet Oncology, 23(5), 650-658. View this article in WRRO
- Measuring patient compliance with remote monitoring following discharge from hospital after major surgery (DREAMPath): protocol for a prospective observational study. JMIR Research Protocols, 11(4).
- Real-world evidence from a single U.K. cancer center for atezolizumab in second-line setting in advanced urothelial cancer: Moving beyond clinical trials.. Journal of Clinical Oncology, 40(6_suppl), 461-461.
- DASL-HiCaP: Darolutamide augments standard therapy for localized very high-risk cancer of the prostate (ANZUP1801). a randomized phase 3 double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation.. Journal of Clinical Oncology, 40(6_suppl), TPS284-TPS284.
- A phase 3, randomized, open-label, multicenter, global study of the efficacy and safety of durvalumab (D) + tremelimumab (T) + enfortumab vedotin (EV) or D + EV for neoadjuvant treatment in cisplatin-ineligible muscle-invasive bladder cancer (MIBC) (VOLGA).. Journal of Clinical Oncology, 40(6_suppl), TPS579-TPS579.
- Robot assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy: Results from the iROC prospective randomised controlled trial. European Urology, 81, S1125-S1125.
- Study EV-104: Phase 1 study of intravesical enfortumab vedotin for treatment of patients with Non-Muscle Invasive Bladder Cancer (NMIBC) (Trial in Progress). European Urology, 81, S507-S507.
- The optimal dissemination of scientific manuscripts via social media: A prospective randomized trial comparing visual abstracts with key figures using consecutive original manuscripts published in European Urology. European Urology, 81, S142-S143.
- Optimal Dissemination of Scientific Manuscripts via Social Media: A Prospective Trial Comparing Visual Abstracts Versus Key Figures in Consecutive Original Manuscripts Published in European Urology. European Urology.
- Developing a Diagnostic Multivariable Prediction Model for Urinary Tract Cancer in Patients Referred with Haematuria: Results from the IDENTIFY Collaborative Study. European Urology Focus.
- Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data. The Journal of Cardiovascular Surgery, 62(6).
- SARS‐CoV‐2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia, 77(1), 28-39.
- Genome-wide meta-analysis identifies novel genes associated with recurrence and progression in non–muscle-invasive bladder cancer. European Urology Oncology, 5(1), 70-83.
- Impact of Bacillus Calmette-Guérin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infection. BJS Open, 5(6).
- Defining factors associated with high-quality surgery following radical cystectomy : analysis of the British Association of Urological Surgeons cystectomy audit. European Urology Open Science, 33, 1-10.
- Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study.. Lancet Oncol.
- Radical cystectomy in England from 2013 to 2019 on 12,644 patients : an analysis of national trends and comparison of surgical approaches using Hospital Episode Statistics data. BJUI Compass, 2(5), 338-347.
- PD59-10 FACTORS ASSOCIATED WITH HIGH-QUALITY SURGERY FOLLOWING RADICAL CYSTECTOMY: ANALYSIS OF THE BRITISH ASSOCIATION OF UROLOGICAL SURGEONS (BAUS) CYSTECTOMY AUDIT. Journal of Urology, 206(Supplement 3).
- The Scottish Bladder Cancer Quality Performance Indicators Influencing Outcomes, Prognosis, and Surveillance (Scot BC Quality OPS) Clinical Project. European Urology Focus.
- Prostate-specific Antigen Testing as Part of a Risk-Adapted Early Detection Strategy for Prostate Cancer: European Association of Urology Position and Recommendations for 2021. European Urology.
- Effects of pre‐operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia, 76(11), 1454-1464.
- The European Urology Commitment to Gender Equity and Diversity: Expanding Cognitive Diversity through Inclusivity at the Podium. European Urology.
- Using a remote monitoring kit to predict re-admissions for patients discharged following radical cystectomy. European Urology, 79, S1385-S1385.
- Defining factors associated with high-quality surgery following radical cystectomy: Analysis of the British Association of Urological Surgeons (BAUS) cystectomy audit. European Urology, 79, S1151-S1151.
- Reply to Trey Durdin, Alvin Goh, and Eugene Pietzak. Can an Imaging-guided Pathway Replace the Current Paradigm for Muscle-invasive Bladder Cancer? Eur Urol. In press. https://doi.org/10.1016/j.eururo.2021.03.018. European Urology.
- Prehabilitation Exercise Before Urologic Cancer Surgery: A Systematic and Interdisciplinary Review. European Urology.
- Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study. The Journal of Thoracic and Cardiovascular Surgery, 162(2), e355-e372.
- SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. British Journal of Surgery, 108(9), 1056-1063.
- Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study. Anaesthesia, 76(6), 748-758.
- Comparing an Imaging-guided Pathway with the Standard Pathway for Staging Muscle-invasive Bladder Cancer: Preliminary Data from the BladderPath Study. European Urology.
- A phase III, randomized, open-label, multicenter, global study of efficacy and safety of durvalumab in combination with gemcitabine plus cisplatin for neoadjuvant treatment followed by durvalumab alone for adjuvant treatment in muscle-invasive bladder cancer (NIAGARA).. Journal of Clinical Oncology, 39(6_suppl), TPS505-TPS505.
- DASL-HiCaP: Darolutamide augments standard therapy for localized very high-risk cancer of the prostate (ANZUP1801)—A randomized phase III double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation.. Journal of Clinical Oncology, 39(6_suppl), TPS266-TPS266.
- Updated outcomes of POUT: A phase III randomized trial of peri-operative chemotherapy versus surveillance in upper tract urothelial cancer (UTUC).. Journal of Clinical Oncology, 39(6_suppl), 455-455.
- Quality of life after bladder cancer: a cross-sectional survey of patient-reported outcomes. European Urology. View this article in WRRO
- Phase I trial of DNA methyltransferase inhibitor guadecitabine combined with cisplatin and gemcitabine for solid malignancies including urothelial carcinoma (SPIRE). Clinical Cancer Research. View this article in WRRO
- Men’s experiences of radiotherapy treatment for localized prostate cancer and its long-term treatment side effects: a longitudinal qualitative study. Cancer Causes & Control, 32(3), 261-269.
- Radical cystectomy against intravesical BCG for high-risk high-grade nonmuscle invasive bladder cancer: results from the randomized controlled BRAVO-feasibility study. Journal of Clinical Oncology. View this article in WRRO
- Re: Helena Vila-Reyes, G. Joel DeCastro, and James M. McKiernan’s Letter to the Editor re: Yunjin Bai, Yubo Yang, and Yin Tang’s Letter to the Editor re: Andrea Necchi, Marco Bandini, Giuseppina Calareso, et al. Multiparametric Magnetic Resonance Imaging as a Noninvasive Assessment of Tumor Response to Neoadjuvant Pembrolizumab in Muscle-invasive Bladder Cancer: Preliminary Findings from the PURE-01 Study. Eur Urol 2020; 77:636–43. Eur Urol 2020;77:e158: Can mpMRI Replace Conventional Transurethral Resection of Bladder Cancer? Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.08.006. European Urology.
- Telemedicine and smart working: Spanish adaptation of the European Association of Urology recommendations. Actas Urológicas Españolas (English Edition), 44(10), 644-652.
- Occupational bladder cancer: A cross section survey of previous employments, tasks and exposures matched to cancer phenotypes. PLoS ONE, 15(10). View this article in WRRO
- Systematic review and meta-analysis of vesical imaging-reporting and data system (VI-RADS) inter-observer reliability : an added value for muscle invasive bladder cancer detection. Cancers, 12(10).
- Corrigendum to ‘Diagnostic Performance of Vesical Imaging Reporting and Data System for the Prediction of Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis’ [European Urology Oncology 3 (2020) 306-315]. European Urology Oncology, 3(6), 811-811.
- The ProtecT randomised trial cost-effectiveness analysis comparing active monitoring, surgery, or radiotherapy for prostate cancer. British Journal of Cancer, 123(7), 1063-1070.
- The Impact of the COVID-19 Pandemic on Genitourinary Cancer Care: Re-envisioning the Future. European Urology.
- Strategies adopted by men to deal with uncertainty and anxiety when following an active surveillance/monitoring protocol for localised prostate cancer and implications for care: a longitudinal qualitative study embedded within the ProtecT trial. BMJ Open, 10(9).
- TELEMEDICINA Y TRABAJO INTELIGENTE: ADAPTACIÓN AL ESPAÑOL DE LAS RECOMENDACIONES DE LA ASOCIACIÓN EUROPEA DE UROLOGÍA. Actas Urológicas Españolas.
- 694TiP DASL-HiCaP: Darolutamide augments standard therapy for localised very high-risk cancer of the prostate (ANZUP1801). A randomised phase III double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation. Annals of Oncology, 31, S548-S549.
- Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer : the ProtecT three-arm RCT. Health Technology Assessment, 24(37), 1-175.
- Survey of the Impact of COVID-19 on Oncologists’ Decision Making in Cancer. JCO Global Oncology(6), 1248-1257.
- Reply to Gianluca Giannarini, Vincenzo Ficarra, and Claudio Valotto’s Letter to the Editor re: Stephen B. Williams, Marcus G.K. Cumberbatch, Ashish M. Kamat, et al. Reporting Radical Cystectomy Outcomes Following Implementation of Enhanced Recovery After Surgery Protocols: A Systematic Review and Individual Patient Data Meta-analysis. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.06.039. European Urology.
- Best Practices to Optimise Quality and Outcomes of Transurethral Resection of Bladder Tumours. European Urology Oncology.
- Reporting Radical Cystectomy Outcomes Following Implementation of Enhanced Recovery After Surgery Protocols: A Systematic Review and Individual Patient Data Meta-analysis. European Urology, 78(5), 719-730.
- Erratum to ‘Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received’ [European Urology 77 (2020) 320–330]. European Urology, 78(3), e139-e143.
- Open science and open publishing: A new paradigm for the European urology family. European Urology Open Science, 19, 1-2. View this article in WRRO
- Comparison of wearable device measured mobility with patient-reported mobility during peri-operative recovery following radical cystectomy. European Urology Open Science, 19, e1999-e1999.
- Radical cystectomy (open, laparoscopic and robotic) in 12625 patients in England: National trends and peri-operative outcomes from Hospital Episode Statistics data. European Urology Open Science, 19, e2281-e2282.
- Reporting radical cystectomy outcomes following implementation of Enhanced Recovery after Surgery (ERAS) protocols: A systematic review and individual patient data meta-analysis. European Urology Open Science, 19, e2280-e2280.
- Meta-analysis of six genome-wide association studies identifies novel loci associated with recurrence and progression of non-muscle invasive bladder cancer. European Urology Open Science, 19, e1369-e1369.
- Replacing TURBT with mpMRI for staging MIBC: Pilot data from the BladderPath trial. European Urology Open Science, 19, e824-e825.
- Molecular Characterization of Upper Tract Urothelial Carcinoma in the Era of Next-generation Sequencing: A Systematic Review of the Current Literature. European Urology, 78(2), 209-220.
- The Impact of Centralised Services on Metric Reflecting High-quality Performance: Outcomes from 1110 Consecutive Radical Cystectomies at a Single Centre. European Urology Focus.
- Safety and immunogenicity of novel 5T4 viral vectored vaccination regimens in early stage prostate cancer: a phase I clinical trial. Journal for ImmunoTherapy of Cancer, 8(1), e000928-e000928.
- Phase I/II open label nonrandomized safety and efficacy study of the viral vectored ChAdOx1-MVA 5T4 immunotherapy in combination with PD-1 checkpoint blockade in intermediate-risk localized or locally advanced prostate cancer and advanced metastatic prostate cancer.. Journal of Clinical Oncology, 38(15_suppl), TPS3170-TPS3170.
- Risks from Deferring Treatment for Genitourinary Cancers: A Collaborative Review to Aid Triage and Management During the COVID-19 Pandemic. European Urology, 78(1), 29-42.
- Comparing open-radical cystectomy and robot-assisted radical cystectomy. Current Opinion in Urology, 30(3), 400-406.
- Biomarkers predicting oncological outcomes of high-risk non-muscle-invasive bladder cancer. Minerva Urologica e Nefrologica, 72(3).
- Considerations in the Triage of Urologic Surgeries During the COVID-19 Pandemic. European Urology, 77(6), 663-666.
- PD51-11 REPORTING RADICAL CYSTECTOMY OUTCOMES FOLLOWING IMPLEMENTATION OF ENHANCED RECOVERY AFTER SURGERY (ERAS) PROTOCOLS. The Journal of Urology, 203, e1087-e1088.
- VI-RADS Scoring Criteria for Alternative Risk-adapted Strategies in the Management of Bladder Cancer During the COVID-19 Pandemic. European Urology, 78(1), e18-e20.
- The Use of Nonsteroidal Anti-inflammatory Drugs in Urological Practice in the COVID-19 Era: Is “Safe Better than Sorry”?. European Urology, 78(2), 134-135.
- Adjuvant chemotherapy in upper tract urothelial carcinoma (the POUT trial): a phase 3, open-label, randomised controlled trial. The Lancet, 395(10232), 1268-1277. View this article in WRRO
- CALIBER - A phase II randomised feasibility trial of chemoablation with mitomycin versus surgical management in low risk non-muscle invasive bladder cancer. BJU International. View this article in WRRO
- Transurethral Resection of Bladder Tumour: The Neglected Procedure in the Technology Race in Bladder Cancer. European Urology, 77(6), 669-670.
- Diagnostic Performance of Vesical Imaging Reporting and Data System for the Prediction of Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis. European Urology Oncology, 3(3), 306-315.
- IDENTIFY : The investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer: A multicentre cohort study. International Journal of Surgery Protocols, 21, 8-12. View this article in WRRO
- Replacing TURBT with mpMRI for staging MIBC: Pilot data from the BladderPath study.. Journal of Clinical Oncology, 38(6_suppl), 446-446.
- DASL-HiCAP (ANZUP1801): The impact of darolutamide on standard therapy for localized very high-risk cancer of the prostate—A randomized phase III double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation in very high-risk, clinically localized prostate cancer.. Journal of Clinical Oncology, 38(6_suppl), TPS385-TPS385.
- A randomized phase II study of erdafitinib (ERDA) versus intravesical chemotherapy (IC) in patients with high-risk nonmuscle invasive bladder cancer (HR-NMIBC) with FGFR mutations or fusions, who recurred after Bacillus Calmette-Guérin (BCG) therapy.. Journal of Clinical Oncology, 38(6_suppl), TPS603-TPS603.
- Reply to Charalampos Fragkoulis, Georgios Papadopoulos, and Konstantinos Ntoumas’s Letter to the Editor re: Francesco Del Giudice, Giovanni Barchetti, Ettore De Berardinis, et al. Prospective Assessment of Vesical Imaging Reporting and Data System (VI-RADS) and its Clinical Impact on the Management of High-risk Non–muscle-invasive Bladder Cancer Patients Candidate for Repeated Transurethral Resection. Eur Urol 2020;77:101–9. European Urology, 77(4), e94-e95.
- The ProtecT trial: analysis of the patient cohort, baseline risk stratification and disease progression. BJU International, 125(4), 506-514.
- Negative Predictive Value of Multiparametric Magnetic Resonance Imaging in the Detection of Clinically Significant Prostate Cancer in the Prostate Imaging Reporting and Data System Era: A Systematic Review and Meta-analysis. European Urology.
- Telemedicine and Smart Working: Recommendations of the European Association of Urology. European Urology.
- Festschrift in Honor of Professor Margaret Anne Knowles. Bladder Cancer, 6(4), 537-548.
- Non-visible haematuria for the Detection of Bladder, Upper Tract, and Kidney Cancer: An Updated Systematic Review and Meta-analysis. European Urology, 77(5), 583-598.
- Complication rate after cystectomy following pelvic radiotherapy: an international, multicenter, retrospective series of 682 cases. World Journal of Urology, 38(8), 1959-1968.
- Prospective Assessment of Vesical Imaging Reporting and Data System (VI-RADS) and Its Clinical Impact on the Management of High-risk Non–muscle-invasive Bladder Cancer Patients Candidate for Repeated Transurethral Resection. European Urology, 77(1), 101-109.
- Is Social Media Worth the Risk for Health Care Professionals?. European Urology Focus, 6(3), 427-429.
- Do Not Learn a Technique, Learn the Biology Underlying the Disease: Techniques Evolve, Biology Prevails. European Urology, 77(1), 1-2.
- Ten-year mortality, disease progression, and treatment-related side effects in men with localised prostate cancer from the ProtecT randomised controlled trial according to treatment received. European Urology. View this article in WRRO
- EAU-EANM-ESTRO-ESUR-SIOG Prostate Cancer Guideline Panel Consensus Statements for Deferred Treatment with Curative Intent for Localised Prostate Cancer from an International Collaborative Study (DETECTIVE Study). European Urology, 76(6), 790-813.
- Quality indicators for bladder cancer services : a collaborative review. European Urology. View this article in WRRO
- How to treat a patient with T1 high-grade disease and no tumour on repeat transurethral resection of the bladder?. European Urology Oncology. View this article in WRRO
- Correction:Robot-assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy (iROC): protocol for a randomised controlled trial with internal feasibility study. BMJ Open, 9(8), e020500corr1-e020500corr1.
- Outcomes of radical cystectomy following implementation of enhanced recovery after surgery protocols: A systematic review. Clinical Nutrition ESPEN, 31, 142-142.
- Life and bladder cancer: protocol for a longitudinal and cross-sectional patient-reported outcomes study of Yorkshire (UK) patients. BMJ Open, 9(6), e030850-e030850.
- Factors associated with trial recruitment, preferences, and treatments received were elucidated in a comprehensive cohort study. Journal of Clinical Epidemiology, 113, 200-213.
- Safe Use of Immune Checkpoint Inhibitors in the Multidisciplinary Management of Urological Cancer: The European Association of Urology Position in 2019. European Urology, 76(3), 368-380.
- A phase III, randomized, open label, multicenter, global study of efficacy and safety of durvalumab in combination with gemcitabine+cisplatin (G+C) for neoadjuvant treatment followed by durvalumab alone for adjuvant treatment in muscle-invasive bladder cancer (MIBC) (NIAGARA).. Journal of Clinical Oncology, 37(15_suppl), TPS4592-TPS4592.
- Reply from Authors re: Peter Albers. Volume Matters: Can We Rely on the Evidence? Eur Urol Oncol 2019;2:274–5. European Urology Oncology, 2(3), 276-276.
- Structured Population-based Prostate-specific Antigen Screening for Prostate Cancer: The European Association of Urology Position in 2019. European Urology, 76(2), 142-150.
- Regional Variations in Quality of Survival Among Men with Prostate Cancer Across the United Kingdom. European Urology, 76(2), 228-237.
- MP24-19 NEGATIVE PREDICTIVE VALUE OF MULTI-PARAMETRIC MRI IN DETECTION OF CLINICALLY SIGNIFICANT PROSTATE CANCER: A SYSTEMATIC REVIEW AND META-ANALYSIS. Journal of Urology, 201(Supplement 4).
- Should We Perform Multiparametric Magnetic Resonance Imaging of the Bladder Before Transurethral Resection of Bladder? Time to Reconsider the Rules. European Urology, 76(1), 57-58.
- MP29-12 COMPARATIVE COST-EFFECTIVENESS OF ACTIVE SURVEILLANCE, RADICAL PROSTATECTOMY, AND EXTERNAL BEAM RADIOTHERAPY: LESSONS FROM PROTECT. Journal of Urology, 201(Supplement 4).
- Long term survival after radical cystectomy with respect to centralisation: Outcomes from 1110 patients treated at a single high-volume centre. European Urology Supplements, 18(1), e1134-e1134.
- 12 month results of CALIBER: A phase II randomised feasibility trial of chemoablation with MMC versus surgical management in low risk (LR) non-muscle invasive bladder cancer (NMIBC). European Urology Supplements, 18(1), e762-e763.
- Online professionalism - 2018 update of European Association of Urology (@Uroweb) commendations on the appropriate use of social media. European Urology Supplements, 18(1), e2147-e2148.
- The iROC trial: An RCT comparing intracorporeal robot-assisted vs open radical cystectomy for bladder cancer. European Urology Supplements, 18(1), e1844-e1844.
- Bladder-sparing treatment in MIBC: where do we stand?. Minerva Urologica e Nefrologica, 71(2).
- Multiparametric MRI of the bladder: inter-observer agreement and accuracy with the Vesical Imaging-Reporting and Data System (VI-RADS) at a single reference center. European Radiology, 29(10), 5498-5506.
- Specificity of the metallothionein-1 response by cadmium-exposed normal human urothelial cells. International Journal of Molecular Sciences, 20(6). View this article in WRRO
- Quality of life in men living with advanced and localised prostate cancer in the UK: a population-based study. The Lancet Oncology, 20(3), 436-447. View this article in WRRO
- Robot-assisted versus open cystectomy in the RAZOR trial. The Lancet, 393(10172), 644-645.
- A three-gene methylation marker panel for the nodal metastatic risk assessment of muscle-invasive bladder cancer. Journal of Cancer Research and Clinical Oncology, 145(4), 811-820.
- Re: Enzalutamide with Standard First-line Therapy in Metastatic Prostate Cancer. European Urology, 76(6), 872-873.
- The Immune Landscape of Cancer. Immunity, 51(2), 411-412.
- Management of Patients with Normal Cystoscopy but Positive Cytology or Urine Markers. European Urology Oncology.
- Impact of Anaesthetist Volume on Radical Cystectomy Outcomes. European Urology Focus.
- Innovations in Statistical Review at European Urology. European Urology, 75(1), 1-2.
- Reply to Jeremy Y.C. Teoh, Thomas R.W. Herrmann, and Marek Babjuk's Letter to the Editor re: Valeria Panebianco, Yoshifumi Narumi, Ersan Altun, et al. Multiparametric Magnetic Resonance Imaging for Bladder Cancer: Development of VI-RADS (Vesical Imaging-Reporting and Data System). Eur Urol 2018;74:294–306. European Urology, 75(2), e29-e30.
- Impact of Centralizing Care for Genitourinary Malignancies to High-volume Providers: A Systematic Review. European Urology Oncology, 2(3), 265-273.
- Does the robot have a role in radical cystectomy?. BJU International, 123(3), 380-382.
- Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations. BJU International, 123(2), 284-292.
- Long-term Outcomes from Re-resection for High-risk Non–muscle-invasive Bladder Cancer: A Potential to Rationalize Use. European Urology Focus, 5(4), 650-657.
- Molecular characterization and clinical relevance of metabolic expression subtypes in human cancers. Cell Reports, 23(1), 255-269.e4. View this article in WRRO
- Carcinome urothélial au sein d’un diverticule de vessie : étude multicentrique des caractéristiques cliniques, anatomopathologiques et des résultats oncologiques. Progrès en Urologie, 28(13), 718-718.
- Comprehensive molecular characterization of the hippo signaling pathway in cancer. Cell Reports, 25(5), 1304-1317.e5. View this article in WRRO
- A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily. Cell Systems, 7(4), 422-437.e7.
- Epidemiology of Bladder Cancer: A Systematic Review and Contemporary Update of Risk Factors in 2018. European Urology. View this article in WRRO
- Staging the Host: Personalizing Risk Assessment for Radical Cystectomy Patients. European Urology Oncology, 1(4), 292-304.
- Multiparametric Magnetic Resonance Imaging for Bladder Cancer: Development of VI-RADS (Vesical Imaging-Reporting And Data System). European Urology, 74(3), 294-306. View this article in WRRO
- Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients. Cancer Cell, 34(2), 211-224.e6.
- Robot-assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy (iROC): protocol for a randomised controlled trial with internal feasibility study. BMJ Open, 8(8), e020500-e020500. View this article in WRRO
- Reply to Andrea Necchi, Antonella Messina, and Alberto Briganti's Letter to the Editor re: Valeria Panebianco, Yoshifumi Narumi, Ersan Altun, et al. Multiparametric Magnetic Resonance Imaging for Bladder Cancer: Development of VI-RADS (Vesical Imaging-Reporting and Data System). Eur Urol 2018;74:294–306. European Urology, 74(5), e109-e109.
- Corrigendum: A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype. Carcinogenesis, 39(8), 1094-1094.
- An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment. Journal of Clinical Epidemiology, 99, 75-83.
- Active Surveillance for Low-risk Prostate Cancer: The European Association of Urology Position in 2018. European Urology, 74(3), 357-368.
- The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports, 23(12), 3698-3698.
- Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer. BJU International, 122(6), 970-977.
- Reply to Mark C. Kendall's Letter to the Editor re: Karl H. Pang, Ruth Groves, Suresh Venugopal, Aidan P. Noon, James W.F. Catto. Prospective Implementation of Enhanced Recovery After Surgery Protocols to Radical Cystectomy. Eur Urol 2018;73:363–71. European Urology, 74(3), e66-e66.
- Repeat Transurethral Resection in Non–muscle-invasive Bladder Cancer: A Systematic Review [Figure presented]. European Urology, 73(6), 925-933. View this article in WRRO
- A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype. Carcinogenesis, 39(6), 798-807. View this article in WRRO
- Multidomain Quantitative Recovery Following Radical Cystectomy for Patients Within the Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion Versus Open Radical Cystectomy Randomised Controlled Trial: The First 30 Patients. European Urology, 74(4), 531-534.
- VANCE: First-in-human phase I study of a novel ChAdOx1-MVA 5T4 vaccine in low and intermediate risk prostate cancer.. Journal of Clinical Oncology, 36(15_suppl), 3018-3018.
- Intense Exercise for Survival among Men with Metastatic Castrate-Resistant Prostate Cancer (INTERVAL-GAP4): a multicentre, randomised, controlled phase III study protocol. BMJ Open, 8(5), e022899-e022899.
- Health-related quality of life after treatment for bladder cancer in England. British Journal of Cancer. View this article in WRRO
- Evaluating patient-reported outcome measures (PROMs) for bladder cancer: a systematic review using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist. BJU International. View this article in WRRO
- Genomic and Functional Approaches to Understanding Cancer Aneuploidy. Cancer Cell, 33(4), 676-689.e3.
- A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer Cell, 33(4), 690-705.e9.
- Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. Cancer Cell, 33(4), 721-735.e8.
- lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. Cancer Cell, 33(4), 706-720.e9.
- Pathogenic Germline Variants in 10,389 Adult Cancers. Cell, 173(2), 355-370.e14.
- Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell, 173(2), 305-320.e10.
- Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell, 173(2), 371-385.e18.
- Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell, 173(2), 291-304.e6.
- An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. Cell, 173(2), 400-416.e11.
- A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples. Cell, 173(2), 386-399.e12.
- Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell, 173(2), 321-337.e10.
- Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell, 173(2), 338-354.e15.
- Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types. Cell Reports, 23(1), 282-296.e4.
- Systematic Analysis of Splice-Site-Creating Mutations in Cancer. Cell Reports, 23(1), 270-281.e3. View this article in WRRO
- Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Reports, 23(1), 239-254.e6.
- Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images. Cell Reports, 23(1), 181-193.e7.
- Driver fusions and their implications in the development and treatment of human cancers. Cell Reports, 23(1), 227-238.e3. View this article in WRRO
- Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. Cell Reports, 23(1), 297-312.e12.
- The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports, 23(1), 313-326.e5.
- SPIRE - combining SGI-110 with cisplatin and gemcitabine chemotherapy for solid malignancies including bladder cancer: Study protocol for a phase Ib/randomised IIa open label clinical trial. Trials, 19(1). View this article in WRRO
- MP18-03 RESULTS OF POUT - A PHASE III RANDOMISED TRIAL OF PERI-OPERATIVE CHEMOTHERAPY VERSUS SURVEILLANCE IN UPPER TRACT UROTHELIAL CANCER (UTUC). Journal of Urology, 199(4S).
- MP41-14 UROTHELIAL CARCINOMA IN BLADDER DIVERTICULA: A MULTICENTER ANALYSIS OF CHARACTERISTICS AND TREATMENT OUTCOME. Journal of Urology, 199(4S).
- MP08-08 DISCHARGE OF LOW RISK NON MUSCLE INVASIVE BLADDER CANCER AFTER ONE YEAR: RESULTS OF A BAUS/BAUN NATIONAL SURVEY OF THE ADOPTION OF THE NICE BLADDER CANCER GUIDELINES RECOMMENDATIONS IN THE UK. Journal of Urology, 199(4S).
- PD66-04 RESULTS OF CALIBER: A PHASE II RANDOMISED FEASIBILITY TRIAL OF CHEMOABLATION VERSUS SURGICAL MANAGEMENT IN LOW RISK NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC). Journal of Urology, 199(4S).
- MP71-18 THE USE OF FITNESS TRACKER IN MONITORING FUNCTIONAL ACTIVITY OF PATIENTS UNDERGOING RADICAL CYSTECTOMY FOR BLADDER CANCER: A FEASIBILITY REPORT AND ANALYSIS AS PART OF THE MULTI-CENTRE RANDOMISED IROC TRIAL. Journal of Urology, 199(4S). View this article in WRRO
- A prospective cohort and extended comprehensive-cohort design provided insights about the generalizability of a pragmatic trial: the ProtecT prostate cancer trial. Journal of Clinical Epidemiology, 96, 35-46.
- Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Systems, 6(3), 271-281.e7.
- Urinary, bowel and sexual health in older men from Northern Ireland. BJU International. View this article in WRRO
- Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality. JAMA, 319(9), 883-883.
- Disease and patient’s characteristics in elderly (≥75 years) treated with radical cystectomy: results of a large multicentre retrospective series. European Urology Supplements, 17(2), e1024-e1025.
- Discharge of low risk non muscle invasive bladder cancer after one year: Results of a national survey of the adoption of the NICE bladder cancer guidelines recommendations in the UK. European Urology Supplements, 17(2), e1068-e1068.
- Urothelial carcinoma in bladder diverticula: A multicenter analysis of characteristics and treatment outcome in 110 patients. European Urology Supplements, 17(2), e532-e533.
- Results of CALIBER: A phase II randomised feasibility trial of chemoablation versus surgical management in low risk non-muscle invasive bladder cancer. European Urology Supplements, 17(2), e1062-e1063.
- Results of POUT - a phase III randomised trial of peri-operative chemotherapy versus surveillance in upper tract urothelial cancer (UTUC). European Urology Supplements, 17(2), e1431-e1432.
- Response to Claire Vale, David Fisher, Jayne Tierney, Ian White, Matthew Sydes, and James Carpenter's Letter to the Editor re: Christopher J.D. Wallis, Zachary Klaassen, Bimal Bhindi, et al. Comparison of Abiraterone Acetate and Docetaxel with Androgen Deprivation Therapy in High-risk and Metastatic Hormone-naïve Prostate Cancer: A Systematic Review and Network Meta-analysis. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2017.10.002. European Urology, 73(3), e51-e51.
- Prospective Implementation of Enhanced Recovery After Surgery Protocols to Radical Cystectomy. European Urology, 73(3), 363-371. View this article in WRRO
- Improving Standards of Care through the Publication of Surgeon Identifiable Outcome Data in Urology. European Urology, 74(1), 1-3.
- Correction to: Meeting abstracts from the 4th International Clinical Trials Methodology Conference (ICTMC) and the 38th Annual Meeting of the Society for Clinical Trials. Trials, 19(1).
- Online Professionalism—2018 Update of European Association of Urology (@Uroweb) Recommendations on the Appropriate Use of Social Media. European Urology, 74(5), 644-650.
- Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell, 174(4), 1034-1035.
- Treatment Strategy for Newly Diagnosed T1 High-grade Bladder Urothelial Carcinoma: New Insights and Updated Recommendations. European Urology, 74(5), 597-608.
- Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports, 23(1), 194-212.e6.
- Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. Cell Reports, 23(1), 213-226.e3.
- Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. Cell Reports, 23(1), 172-180.e3.
- The Immune Landscape of Cancer. Immunity, 48(4), 812-830.e14.
- Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Systems, 6(3), 282-300.e2.
- Re: Comprehensive Molecular Characterization of Muscle Invasive Bladder Cancer. European Urology, 73(3), 479-480. View this article in WRRO
- Predicting Response to Intravesical Bacillus Calmette-Guérin Immunotherapy: Are We There Yet? A Systematic Review. European Urology, 73(5), 738-748.
- Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer. Cell, 171(3), 540-556.e25.
- A New Fuzzy Modeling Framework for Integrated Risk Prognosis and Therapy of Bladder Cancer Patients. IEEE Transactions on Fuzzy Systems, 26(3), 155-1577. View this article in WRRO
- Radical cystectomy (bladder removal) against intravesical BCG immunotherapy for high-risk non-muscle invasive bladder cancer (BRAVO): A protocol for a randomised controlled feasibility study. BMJ Open, 7(8). View this article in WRRO
- Speeding up recovery from radical cystectomy: how low can we go?. BJU International, 120(2), 162-163. View this article in WRRO
- Changing current practice in urology: Improving guideline development and implementation through stakeholder engagement. European Urology, 72(2), 161-163. View this article in WRRO
- E-cigarettes and Urologic Health: A Collaborative Review of Toxicology, Epidemiology, and Potential Risks. European Urology, 71(6), 915-923.
- A core outcome set for localised prostate cancer effectiveness trials. BJU International.
- Evaluation of a short RNA within Prostate Cancer Gene 3 in the predictive role for future cancer using non-malignant prostate biopsies. PLOS ONE, 12(4). View this article in WRRO
- A phase III study comparing partial prostate ablation versus radical prostatectomy (PART) in intermediate risk prostate cancer – initial data from the feasibility study. European Urology Supplements, 16(3), e1316-e1318.
- The application of ERAS pathways to radical cystectomy: Outcomes from 482 consecutive cases. European Urology Supplements, 16(3), e1023-e1023.
- What is #urology tweeting about? Strategic assessment of Twitter communication in urology. European Urology Supplements, 16(3), e1440-e1442.
- Mortality Among Men with Advanced Prostate Cancer Excluded from the ProtecT Trial. European Urology. View this article in WRRO
- Update of the ICUD-SIU consultation on upper tract urothelial carcinoma 2016: treatment of low-risk upper tract urothelial carcinoma. World Journal of Urology, 35(3), 355-365. View this article in WRRO
- Precision surgery and genitourinary cancers. European Journal of Surgical Oncology (EJSO). View this article in WRRO
- The patients’ experience of a bladder cancer diagnosis: a systematic review of the qualitative evidence. Journal of Cancer Survivorship. View this article in WRRO
- An evaluation of morphological and functional multi-parametric MRI sequences in classifying non-muscle and muscle invasive bladder cancer. European Radiology.
- Robotic intracorporeal urinary diversion: Practical review of current surgical techniques. Minerva Urologica e Nefrologica, 69(1), 14-25.
- In Defense of Randomized Clinical Trials in Surgery: Let Us Not Forget Archie Cochrane's Legacy. European Urology. View this article in WRRO
- Quantification of Urology Related Twitter Traffic Activity through a Standardized List of Social Media Communication Descriptors. Urology Practice, 4(4), 349-354.
- Kidney Cancer: Many Important Advances but Still a Lot to Debate. European Urology Focus, 2(6), 565-566.
- In Reply to Samaratunga et al. International Journal of Radiation Oncology*Biology*Physics, 96(5), 1127-1128.
- Life after prostate cancer diagnosis: protocol for a UK-wide patient-reported outcomes study. BMJ Open, 6(12). View this article in WRRO
- The Use of Biomarkers to Manage Men with Metastatic Prostate Cancer: One Day, But Not Yet. European Urology Focus, 2(5), 467-468.
- Reply to letter to editor about new Gleason grading system: Statement from the editors of six journals. Urologic Oncology: Seminars and Original Investigations, 34(11), 481-481.
- Altered RECQL5 expression in urothelial bladder carcinoma increases cellular proliferation and makes RECQL5 helicase activity a novel target for chemotherapy.. Oncotarget. View this article in WRRO
- 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer. New England Journal of Medicine, 375(15), 1415-1424. View this article in WRRO
- Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer. New England Journal of Medicine, 375(15), 1425-1437. View this article in WRRO
- Consensus Guidelines for Reporting Prostate Cancer Gleason Grade Reply. JOURNAL OF UROLOGY, 196(4), 1322-1323.
- Beware of Bugs! Hot Issues in Urinary Tract Infections and Inflammation. European Urology Focus, 2(4), 339-340.
- The Problem Is Not What to Do with Indolent and Harmless Prostate Cancer—The Problem Is How to Avoid Finding These Cancers. European Urology, 70(4), 547-548.
- Reply to Wentao Liu, Xiaokun Zhao, Zhaohui Zhong's Letter to the Editor re: Marcus G. Cumberbatch, Matteo Rota, James W.F. Catto, Carlo La Vecchia. The Role of Tobacco Smoke in Bladder and Kidney Carcinogenesis: A Comparison of Exposures and Meta-analysis of Incidence and Mortality Risks. Eur Urol 2016;70:458–66. European Urology, 70(4), e106-e107.
- Enhanced recovery after robot-assisted radical cystectomy: EAU Robotic Urology Section (ERUS) scientific working group consensus statement view. European Urology Supplements, 15(7), 225-225.
- Consensus guidelines for reporting prostate cancer Gleason Grade Reply. BJU INTERNATIONAL, 118(3), E2-E2.
- Radiotherapy for Prostate Cancer: is it ‘what you do’ or ‘the way that you do it’? A UK Perspective on Technique and Quality Assurance. Clinical Oncology, 28(9), e92-e100.
- The Role of Tobacco Smoke in Bladder and Kidney Carcinogenesis: A Comparison of Exposures and Meta-analysis of Incidence and Mortality Risks. European Urology, 70(3), 458-466. View this article in WRRO
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- Mitogen-activated protein kinase signaling is activated in prostate tumors but not mediated by B-RAF mutations - Editorial comment. EUROPEAN UROLOGY, 50(5), 1109-1110.
- The changing face of prostate cancer: can gains in epigenetic knowledge translate into improvements in clinical care?. J Mol Med (Berl), 84(11), 883-885.
- Re: Novel Blood Biomarkers of Human Urinary Bladder Cancer. European Urology, 50(4), 862-862.
- Evidence for the early onset of aberrant promoter methylation in urothelial carcinoma.. J Pathol, 209(3), 336-343.
- Multifocal urothelial cancers with the mutator phenotype are of monoclonal origin and require panurothelial treatment for tumor clearance.. J Urol, 175(6), 2323-2330.
- Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer.. Oncogene, 25(20), 2953-2960.
- A GENE-PROMOTER HYPERMETHYLATION PANEL TO DETECT TRANSITIONAL CELL CARCINOMA OF THE BLADDER. European Urology Supplements, 5(2), 37-37.
- MICROSATELLITE INSTABILITY AS PREDICTOR OF SURVIVAL IN PATIENTS WITH INVASIVE UPPER URINARY TRACT TRANSITIONAL CELL CARCINOMA. European Urology Supplements, 5(2), 114-114.
- Methylational urinalysis: a prospective study of bladder cancer patients and age stratified benign controls.. Oncogene, 25(13), 1984-1988.
- 23 DNA promoter methylation in urothelial cancer: a feature of the invasive phenotype and a novel therapeutic target. BJU International, 97, 7-7.
- 22 A gene promoter hypermethylation panel to detect transitional cell carcinoma of the bladder. BJU International, 97, 6-7.
- 21 Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer. BJU International, 97, 6-6.
- Neuro-fuzzy modeling: an accurate and interpretable method for predicting bladder cancer progression.. J Urol, 175(2), 474-479.
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- Mutation of the FGFR3 oncogene is an independent and favorable prognostic factor for tumor-specific survival in patients with urothelial carcinoma of the upper urinary tract. Verhandlungen der Deutschen Gesellschaft für Pathologie, 90, 244-252.
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- Promoter hyper-methylation of calcium binding proteins S100A6 and S100A2 in human prostate cancer.. Prostate, 65(4), 322-330.
- The laparoscopic nephrectomy learning curve: a single centre's development of a de novo practice.. Postgrad Med J, 81(959), 599-603.
- Effects of deworming of cow-calf beef herds in brazilian savannas. Pesquisa Veterinaria Brasileira, 25(3), 188-194.
- Characterization of the specificity of the humoral response to Pythium insidiosum antigens. Journal de Mycologie Médicale, 15(2), 63-68.
- Aberrant promoter methylation in pre-malignant and invasive tumours of the urinary bladder. BJU INTERNATIONAL, 95, 65-65.
- Comparing gene promoter methylation frequencies in urine from patients with bladder cancer with urine from non-cancerous young and elderly control patients. BJU INTERNATIONAL, 95, 63-64.
- Microsatellite instability as predictor of survival in patients with invasive upper urinary tract transitional cell carcinoma.. Urology, 65(6), 1233-1237.
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- Haematuria. Surgery (Oxford), 23(3), 114-116.
- 64 Promoter methylation and microsatellite mutation reveals the clonal relationship of multiple transitional cell carcinoma with the mutator phenotype. European Urology Supplements, 4(3), 18-18.
- Urological diagnosis: history, examination and investigations. Surgery (Oxford), 23(3), 108-113.
- Assessing the patient with a urological problem. Foundation Years, 1(3), 1-7.
- Promoter methylation and microsatellite mutation reveals the clonal relationship of multiple urothelial carcinomas with mutator phenotype. Verhandlungen der Deutschen Gesellschaft für Pathologie, 89, 225-233.
- The road to cystectomy: Who, when and why?. EAU Update Series, 3(3 SPEC. ISS.), 118-128.
- The role of genetic instability in the pathogenesis and progression of urothelial carcinoma. EAU Update Series, 3(4), 180-188.
- The use of proteomics in urological research. EAU Update Series, 3(4), 171-179.
- [Promoter methylation and microsatellite mutation reveals the clonal relationship of multiple urothelial carcinomas with mutator phenotype].. Verh Dtsch Ges Pathol, 89, 225-233.
- Less is more: artificial intelligence and gene-expression arrays.. Lancet, 364(9450), 2003-2004.
- Proteomic analysis of voided urine after prostatic massage from patients with prostate cancer: a pilot study.. Urology, 64(6), 1238-1243.
- Dysregulated expression of S100A11 (calgizzarin) in prostate cancer and precursor lesions.. Hum Pathol, 35(11), 1385-1391.
- S100A6 (Calcyclin) is a prostate basal cell marker absent in prostate cancer and its precursors.. Br J Cancer, 91(4), 739-744. View this article in WRRO
- Microsatellite instability as indicator of MSH2 gene mutation in patients with upper urinary tract transitional cell carcinoma. Journal of Medical Genetics, 41(7), e91-e91.
- 1083: Proteomic Analysis of Voided Urine following Prostatic Massage Reveals Tumour Specific Alterations. Journal of Urology, 171(4S), 286-286.
- 854 Association of cytochrome P450 1B1 VAL432LEU polymorphism and prostate cancer risk. European Urology Supplements, 3(2), 216-216.
- 76 Proteomic analysis of voided urine following prostatic massage reveals tumour specific alterations. European Urology Supplements, 3(2), 21-21.
- 205 Proteomics and immunohistochemistry identify loss of nucleophosmin (B23) expression in bladder transitional cell carcinomas. European Urology Supplements, 3(2), 54-54.
- 452 Calgizzarin (S100A11) immunostaining pattern is altered in prostate cancer suggesting a role in tumourigenesis. European Urology Supplements, 3(2), 115-115.
- Artificial intelligence for the prediction bladder cancer. Biomedical Engineering - Applications, Basis and Communications, 16(2), 49-58.
- Genetic instability and transitional cell carcinoma of the bladder.. BJU Int, 93(1), 19-24.
- Distinct patterns of microsatellite instability are seen in tumours of the urinary tract.. Oncogene, 22(54), 8699-8706.
- Artificial intelligence in predicting bladder cancer outcome: a comparison of neuro-fuzzy modeling and artificial neural networks.. Clin Cancer Res, 9(11), 4172-4177.
- Differential expression of hMLH1 and hMSH2 is related to bladder cancer grade, stage and prognosis but not microsatellite instability.. Int J Cancer, 105(4), 484-490.
- Instability at selected microsatellite tetra-nucleotide repeats in prostate cancer. European Urology Supplements, 2(1), 60-60.
- The application of artificial intelligence in predicting outcome of bladder cancer: A comparison of neuro-fuzzy modelling and artificial neural networks. European Urology Supplements, 2(1), 66-66.
- Effectiveness and cost-effectiveness of prognostic markers in prostate cancer.. Br J Cancer, 88(1), 31-35. View this article in WRRO
- Proteomics and immunohistochemistry identify loss of nucleophosmin (B23) expression in bladder transitional cell carcinomas. European Urology, Supplements, 2(6), 69.
- Proteomic analysis of voided urine following prostatic massage reveals tumour specific alterations. European Urology, Supplements, 2(6), 70.
- Calgizzarin (S100A11) immunostaining pattern is altered in prostate cancer suggesting a role in tumourigenesis. European Urology, Supplements, 2(6), 68.
- Haematuria. Surgery (Oxford), 20(11), 255-257.
- Urological Diagnosis: History and Investigations. Surgery (Oxford), 20(11), 249-254.
- Pancreatic debridement in a district general hospital--viable or vulnerable?. Ann R Coll Surg Engl, 84(5), 309-313.
- Differential expression of mismatch repair proteins, MLH1 and MSH2, in Transitional Cell Carcinoma (TCC) of the bladder. European Urology Supplements, 1(1), 22-22.
- Equine pythiosis in the Brazilian Pantanal region: Clinical and pathological findings of typical and atypical cases. Pesquisa Veterinaria Brasileira, 21(4), 151-156.
- Prostate specific antigen: biology, biochemistry and available commercial assays.. Ann Clin Biochem, 38(Pt 6), 633-651.
- Natality rate of cows and development of calves submitted to early weaning in the Pantanal region, Brazil. Pesquisa Agropecuaria Brasileira, 36(9), 1205-1211.
- Alternative management for weaned Nelore calves in the Pantanal's native pastures. Pesquisa Agropecuaria Brasileira, 35(10), 2099-2105.
- Spontaneous Transpyloric Migration of a Ballooned Nasojejunal Tube: A Randomized Controlled Trial. Journal of Parenteral and Enteral Nutrition, 24(4), 240-243.
- Hepatobiliary cystadenoma presenting with intermittent inferior vena caval obstruction.. J Hepatobiliary Pancreat Surg, 6(3), 324-326.
- . Mycopathologia, 141(3), 123-125.
- An abdominal mass following a road traffic accident.. Postgrad Med J, 74(874), 501-502.
- Recurrence of adult groin hernias five years after repair in a district general hospital. BRITISH JOURNAL OF SURGERY, 85, 17-17.
- Topical glyceryl trinitrate cream for anal fissure.. Br J Surg, 85(6), 874-875.
- Closed drainage versus open packing of infected pancreatic necrosis. American Surgeon, 61(7), 612-618.
- Helminth parasites of capybaras (Hydrochaeris hydrochaeris) on sub-region of Nhecolândia, Pantanal, Mato Grosso do Sul. Revista brasileira de biologia, 54(1), 39-48.
- Stoma care. Prescribers' Journal, 33(3), 111-121.
- Angiolipoma of the stomach as a cause of chronic upper gastrointestinal bleeding. Surgical Endoscopy, 3(2), 106-108.
- Spontaneous Dissecting Intramural Haematoma of the Oesophagus: A Rare Cause of Haematemesis and Dysphagia. Endoscopy, 13(03), 128-130.
- Cecal Volvulus. Archives of Surgery, 115(3), 273-273.
- Hepatobiliary Scanning in the Diagnosis of Acute Cholecystitis. Archives of Surgery, 115(4), 540-540.
- IDEAS AND EXPERIENCE IN THE POLITICAL THOUGHT OF AQUINAS. Past and Present, 71(1), 3-21.
- A case of duodenal tuberculosis. The American Journal of Digestive Diseases, 19(6), 575-579.
- An alleged Great Council of 1374. The English Historical Review, LXXXII(CCCXXV), 764-771.
- Multiple Liver Abscesses in Hydatid Disease. The British Journal of Radiology, 37(443), 859-860.
- Toxic Epidermal Necrolysis Occurring in a Child. BMJ, 2(5151), 544-545.
- SCHISTOSOMA CATTOI, A NEW BLOOD FLUKE OF MAN. BMJ, 1(2297), 11-26.
- Understanding the long‐term impact of the COVID‐19 pandemic on non‐muscle‐invasive bladder cancer outcomes: 12‐Month follow‐up data from the international, prospective COVIDSurg Cancer study. BJUI Compass.
- Real‐word outcomes for high‐risk non‐muscle‐invasive bladder cancer: screened patients for the
BRAVO trial. BJU International. - Perioperative Durvalumab with Neoadjuvant Chemotherapy in Operable Bladder Cancer. New England Journal of Medicine.
- National audit of patient reported experience of radical cystectomy for bladder cancer pathways. BJUI Compass.
- Image directed redesign of bladder cancer treatment pathways: the BladderPath RCT. Health Technology Assessment, 1-65.
- Blood Transfusion, Radical Cystectomy, and Cancer Recurrence: A New Look at an Old Story. Comment on Ladner et al. Perioperative Blood Transfusion Is Associated with Worse Survival in Patients Undergoing Radical Cystectomy after Neoadjuvant Chemotherapy for Muscle-Invasive Bladder Cancer. Soc. Int. Urol. J. 2024, 5, 202–213. Société Internationale d’Urologie Journal, 5(3), 244-246.
- Improved Disease-Free Survival With Adjuvant Chemotherapy After Nephroureterectomy for Upper Tract Urothelial Cancer: Final Results of the POUT Trial. Journal of Clinical Oncology.
- Clinical application of bladder MRI and the Vesical Imaging-Reporting And Data System. Nature Reviews Urology.
- Quality of life after a diagnosis of Bladder Cancer: Longitudinal survey over the first year. BJU International.
- Functional Follow-Up After Cystectomy and Urinary Diversion: A Narrative Review. JU Open Plus, 1(11).
- Oncological Surveillance After Radical Cystectomy: a Narrative Review of the Enhanced Recovery After Surgery Cystectomy Committee. JU Open Plus, 1(10).
- Diagnosis, treatment, and survival from kidney cancer: real‐world
NHS England data between 2013‐2019. BJU International. - Current policies on early detection of prostate cancer create overdiagnosis and inequity with minimal benefit. BMJ, e071082-e071082.
- Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer. New England Journal of Medicine.
- Diagnosis, treatment and survival from bladder, upper urinary tract and urethral cancers: Real world findings from
NHS England between 2013 and 2019. BJU International. - Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection. Scientific Reports, 13(1).
- Gene of the month: NKX3.1. Journal of Clinical Pathology.
- Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score. British Journal of Surgery.
- The development of the C‐PAT: a concise tool to assess the quality of care in the cystectomy pathway. BJU International.
- Bladder cancer: shedding light on the most promising investigational drugs in clinical trials. Expert Opinion on Investigational Drugs.
- The IDENTIFY Study: The Investigation and Detection of Urological Neoplasia in Patients Referred with Suspected Urinary Tract Cancer; A multicentre observational study. BJU International.
- Safety and exceptional immunogenicity of novel 5T4 viral vectored vaccination regimes in early stage prostate cancer: a phase I clinical trial.
- Urethral recurrence after radical cystoprostatectomy: Experience from a high-volume tertiary referral centre. Journal of Clinical Urology, 205141582092051-205141582092051.
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- Exercise interventions for men with prostate cancer.
- Telomere Length Shows No Association with BRCA1 and BRCA2 Mutation Status. PLoS ONE, 9(1), e86659-e86659. View this article in WRRO
- A global evaluation of fronts and precipitation in the ACCESS model. Australian Meteorological and Oceanographic Journal, 63(1), 191-203.
Chapters
- Muscle-invasive bladder cancer In Pang KH, Catto JWF, Myat A & Haldar S (Ed.), Challenging Cases in Urological Surgery (pp. C12-C12.P147). Oxford University PressOxford
- Imaging in Bladder Cancer Surgery, Robotic Urologic Surgery (pp. 627-637). Springer International Publishing
- Prostate Cancer, Basic Urological Sciences (pp. 208-217). CRC Press
- Urothelial and Urethral Cancer, Basic Urological Sciences (pp. 189-207). CRC Press
- Haematuria: Evaluation and Management, Urologic Principles and Practice (pp. 281-286). Springer International Publishing
- How Do I Publish a Scientific Urological Paper?, Practical Tips in Urology (pp. 323-329). Springer London
- Genitourinary malignancies, Oxford Textbook of Fundamentals of Surgery (pp. 373-377). Oxford University Press
- Epidemiology and Risk Factors for Upper Urinary Urothelial Cancers, Upper Tract Urothelial Carcinoma (pp. 1-30). Springer New York
- Hematuria: Evaluation and Management, Practical Urology: Essential Principles and Practice (pp. 351-359). Springer London
- 1349–1412: culture and history, The Cambridge Companion to Medieval English Mysticism (pp. 113-132). Cambridge University Press
- The Cambridge History of the Book in Britain Cambridge University Press
- The epigenetic profile of bladder cancer, Epigenomics (pp. 323-337). Cambridge University Press
Conference proceedings papers
- REMOTE DIGITAL SURVEILLANCE AND MACHINE LEARNING MODELLING TO PREDICT SURVIVAL FOLLOWING RADICAL CYSTECTOMY FOR BLADDER CANCER-A SECONDARY OUTCOME ANALYSIS OF THE IROC TRIAL. JOURNAL OF UROLOGY, Vol. 211(5) (pp E793-E794)
- Use of gene expression patterns to identify unique molecular subtypes in muscle invasive bladder cancer: GUSTO. JOURNAL OF CLINICAL ONCOLOGY, Vol. 42(16)
- MEASURING OBJECTIVE RECOVERY OF ACTIVITY LEVELS USING WEARABLE DEVICES FOLLOWING OPEN VS INTRACORPOREAL ROBOTIC CYSTECTOMY: SECONDARY OUTCOMES ANALYSIS OF THE IROC RANDOMIZED TRIAL. JOURNAL OF UROLOGY, Vol. 209 (pp E985-E985)
- Pathology Against the Clock: Verification of Gene Expression Subtyping for the GUSTO Clinical Trial. JOURNAL OF PATHOLOGY, Vol. 261(SUPPL1) (pp S49-S49)
- ELICITATION OF HEALTH STATE UTILITIES ASSOCIATED PROGRESSION FROM BCG-UNRESPONSIVE NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC) HEALTH STATES. VALUE IN HEALTH, Vol. 25(7) (pp S288-S288)
- RESULTS OF THE INTRACORPOREAL ROBOTIC VS OPEN CYSTECTOMY (IROC) MULTI-CENTRE RANDOMISED TRIAL. JOURNAL OF UROLOGY, Vol. 207(5) (pp E695-E695)
- DASL-HiCaP: Darolutamide augments standard therapy for localized very high-risk cancer of the prostate (ANZUP1801)-A randomized phase 3, double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation. JOURNAL OF CLINICAL ONCOLOGY, Vol. 40(16)
- FACTORS ASSOCIATED WITH HIGH-QUALITY SURGERY FOLLOWING RADICAL CYSTECTOMY: ANALYSIS OF THE BRITISH ASSOCIATION OF UROLOGICAL SURGEONS (BAUS) CYSTECTOMY AUDIT. JOURNAL OF UROLOGY, Vol. 206 (pp E1057-E1058)
- MP61-06 THE ROLE OF WEARABLE DEVICES AND CPET IN PREDICTING MAJOR COMPLICATIONS AFTER RADICAL CYSTECTOMY. The Journal of Urology, Vol. 203 (pp e937-e937)
- Response to guadecitabine (SGI-110) combined with cisplatin and gemcitabine (GCG) in platinum refractory germ cell tumors (GCTs).. JOURNAL OF CLINICAL ONCOLOGY, Vol. 38(15)
- DASL-HiCaP: Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate (ANZUP1801). A randomised phase 3 double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, Vol. 16 (pp 204-204)
- DASL-HiCAP (ANZUP1801): The impact of darolutamide on standard therapy for localized very high-risk cancer of the prostate-A randomized phase III double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation in very high-risk, clinically localized prostate cancer. JOURNAL OF CLINICAL ONCOLOGY, Vol. 38(6)
- A Phase 3, Randomized, Open-Label, Multicenter, Global Study of Efficacy and Safety of Durvalumab in Combination with Gemcitabine plus CiSPLATiN (G plus C) for Neoadjuvant Treatment Followed By Durvalumab Alone for Adjuvant Treatment in Muscle-Invasive Bladder Cancer (MiBC) (NiAGARA). ONCOLOGY RESEARCH AND TREATMENT, Vol. 43 (pp 82-82)
- Phase I/II open label nonrandomized safety and efficacy study of the viral vectored ChAdOx1-MVA 5T4 immunotherapy in combination with PD-1 checkpoint blockade in intermediate-risk localized or locally advanced prostate cancer and advanced metastatic prostate cancer.. JOURNAL OF CLINICAL ONCOLOGY, Vol. 38(15)
- A randomized phase II study of erdafitinib (ERDA) versus intravesical chemotherapy (IC) in patients with high-risk nonmuscle invasive bladder cancer (HR-NMIBC) with FGFR mutations or fusions, who recurred after Bacillus Calmette-Guerin (BCG) therapy. JOURNAL OF CLINICAL ONCOLOGY, Vol. 38(6)
- THE ROLE OF WEARABLE DEVICES AND CPET IN PREDICTING MAJOR COMPLICATIONS AFTER RADICAL CYSTECTOMY. JOURNAL OF UROLOGY, Vol. 203 (pp E937-E937)
- REPORTING RADICAL CYSTECTOMY OUTCOMES FOLLOWING IMPLEMENTATION OF ENHANCED RECOVERY AFTER SURGERY (ERAS) PROTOCOLS: A SYSTEMATIC REVIEW AND INDIVIDUAL PATIENT DATA META-ANALYSIS. JOURNAL OF UROLOGY, Vol. 203 (pp E1087-E1088)
- Low Levels of Intra-Tumour Heterogeneity in Non-Muscle Invasive Bladder Cancer. JOURNAL OF PATHOLOGY, Vol. 249 (pp S12-S12)
- NEGATIVE PREDICTIVE VALUE OF MULTI-PARAMETRIC MRI IN DETECTION OF CLINICALLY SIGNIFICANT PROSTATE CANCER: A SYSTEMATIC REVIEW AND META-ANALYSIS. JOURNAL OF UROLOGY, Vol. 201(4) (pp E341-E341)
- COMPARATIVE COST-EFFECTIVENESS OF ACTIVE SURVEILLANCE, RADICAL PROSTATECTOMY, AND EXTERNAL BEAM RADIOTHERAPY: LESSONS FROM PROTECT. JOURNAL OF UROLOGY, Vol. 201(4) (pp E417-E418)
- Islam and the Urinary Stoma: A Contemporary Theological and Urological Dilemma. European Urology Focus, Vol. 5(2) (pp 301-305)
- Results of POUT - A phase III randomised trial of perioperative chemotherapy versus surveillance in upper tract urothelial cancer (UTUC). BRITISH JOURNAL OF CANCER, Vol. 119(11) (pp 44-45)
- Patient-reported outcomes in men with advanced and localised disease: Results from the UK-wide Life After Prostate Cancer Diagnosis study. BRITISH JOURNAL OF CANCER, Vol. 119(11) (pp 11-11)
- Results of CALIBER: A phase II randomised feasibility trial of chemoablation with MMC versus surgical management in low risk non-muscle invasive bladder cancer (NMIBC). BRITISH JOURNAL OF CANCER, Vol. 119(11) (pp 39-39)
- SPIRE: A phase Ib/ randomised IIa open label clinical trial combining guadecitabine with cisplatin and gemcitabine chemotherapy for solid malignancies including bladder cancer. ANNALS OF ONCOLOGY, Vol. 29
- SPIRE: A phase Ib/ randomised IIa open label clinical trial combining guadecitabine with cisplatin and gemcitabine chemotherapy for solid malignancies including bladder cancer. Annals of Oncology, Vol. 29 (pp viii139-viii139)
- SPIRE: A phase Ib/randomised IIa open label clinical trial combining guadecitabine (SGI-110) with cisplatin and gemcitabine chemotherapy for solid malignancies including bladder cancer.. Journal of Clinical Oncology, Vol. 36(15_suppl) (pp TPS4594-TPS4594)
- RESULTS OF CALIBER: A PHASE II RANDOMISED FEASIBILITY TRIAL OF CHEMOABLATION VERSUS SURGICAL MANAGEMENT IN LOW RISK NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC). JOURNAL OF UROLOGY, Vol. 199(4) (pp E1231-E1231)
- Urothelial Carcinoma in Bladder Diverticula: A Multicenter Analysis of Characteristics and Clinical Outcomes. European Urology Focus
- DISCHARGE OF LOW RISK NON MUSCLE INVASIVE BLADDER CANCER AFTER ONE YEAR: RESULTS OF A BAUS/BAUN NATIONAL SURVEY OF THE ADOPTION OF THE NICE BLADDER CANCER GUIDELINES RECOMMENDATIONS IN THE UK. JOURNAL OF UROLOGY, Vol. 199(4) (pp E98-E99)
- RESULTS OF POUT - A PHASE III RANDOMISED TRIAL OF PERI-OPERATIVE CHEMOTHERAPY VERSUS SURVEILLANCE IN UPPER TRACT UROTHELIAL CANCER (UTUC). JOURNAL OF UROLOGY, Vol. 199(4) (pp E213-E214)
- Life after prostate cancer diagnosis: One step beyond.. Journal of Clinical Oncology, Vol. 36(6_suppl) (pp 40-40)
- Results of POUT: A phase III randomised trial of perioperative chemotherapy versus surveillance in upper tract urothelial cancer (UTUC).. Journal of Clinical Oncology, Vol. 36(6_suppl) (pp 407-407)
- Exercise medicine for metastatic castrate-resistant prostate cancer: a supervised, periodised, progressive and autoregulated program combining resistance and aerobic exercise - the INTERVAL-MCRPC prescription. BJU INTERNATIONAL, Vol. 120 (pp 14-14)
- Evaluation of a short RNA within PCA3 in the predictive role for future cancer using non-malignant prostate biopsies. INTERNATIONAL JOURNAL OF UROLOGY, Vol. 24 (pp 144-144)
- MP21-02 THE LONG TERM OUTCOMES FROM EARLY RE-RESECTION IN PATIENTS WITH HIGH-RISK NON-MUSCLE INVASIVE BLADDER CANCER. Journal of Urology, Vol. 197(4S)
- PD56-08 THE PART TRIAL - A PHASE III STUDY COMPARING PARTIAL PROSTATE ABLATION VERSUS RADICAL PROSTATECTOMY (PART) IN INTERMEDIATE RISK PROSTATE CANCER – EARLY DATA FROM THE FEASIBILITY STUDY. Journal of Urology, Vol. 197(4S)
- Recruitment aids for a phase II randomised trial in low risk bladder cancer. European Journal of Surgical Oncology (EJSO), Vol. 42(11) (pp S244-S244)
- Identification of N6-adenosine methylated RNAs by m6A-seq within prostate cancer. INTERNATIONAL JOURNAL OF UROLOGY, Vol. 23 (pp 131-131)
- Acute toxicity data from POUT: A phase III randomized trial of peri-operative chemotherapy versus surveillance in upper tract urothelial cancer.. Journal of Clinical Oncology, Vol. 34(15_suppl) (pp e16138-e16138)
- Intense exercise for survival among men with metastatic castrate-resistant prostate cancer (INTERVAL – MCRPC): A Movember funded multicenter, randomized, controlled phase III study.. Journal of Clinical Oncology, Vol. 34(15_suppl) (pp TPS5092-TPS5092)
- Workplace patterns and urothelial bladder cancer phenotype - can occupation increase the risk of developing advanced disease?. BJU INTERNATIONAL, Vol. 115 (pp 11-11)
- Workplace patterns and urothelial bladder cancer phenotype - can occupation increase the risk of developing advanced disease?. BJU INTERNATIONAL, Vol. 115 (pp 8-8)
- MP58-03 IDENTIFICATION OF SPECIFIC METHYLATION-BASED BIOMARKERS FOR THE ASSESSMENT OF THE METASTATIC RISK OF MUSCLE INVASIVE BLADDER CANCER. Journal of Urology, Vol. 193(4S)
- MP68-05 RESOLVING INTER-PATHOLOGIST VARIATION IN THE ASSIGNMENT OF GRADE USING WHOLE TRANSCRIPTOME ANALYSIS FOR PATIENTS WITH UROTHELIAL BLADDER CANCER. Journal of Urology, Vol. 193(4S)
- Abstract 1358: Promoter hypermethylation of KISS1R, KiSS1, SEPT9 and CSAD as a prognostic biomarker panel to assess the metastatic potential of muscle invasive bladder tumors. Molecular and Cellular Biology
- 411: Epigenetic mechanisms of cadmium urothelial carcinogenesis. European Journal of Cancer, Vol. 50 (pp S98-S98)
- MP28-06 PROMOTER HYPERMETHYLATION OF KISS1R, KISS1, SEPT9 AND CSAD AS A PROGNOSTIC BIOMARKER PANEL TO ASSESS THE METASTATIC POTENTIAL OF MUSCLE INVASIVE BLADDER TUMORS. Journal of Urology, Vol. 191(4S)
- 1139 SPECIFIC CHANGES IN THE DNA METHYLATION PATTERN ENABLE AN EARLY ASSESSMENT OF THE METASTATIC RISK OF PRIMARY BLADDER TUMOURS. Journal of Urology, Vol. 189(4S)
- 1295 SNAPSHOT OF TRANSURETHRAL RESECTION OF NEW BLADDER TUMOURS IN THE UK AUDIT (STUKA). Journal of Urology, Vol. 189(4S)
- Radial basis function neural-fuzzy model for microarray signature identification. BIOINFORMATICS 2013 - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (pp 134-139)
- 359 MicroRNA-145 Inhibits Myofibroblast Transdifferentiation by Regulating Extracellular Proteoglycan Versican. European Journal of Cancer, Vol. 48 (pp S87-S87)
- Snapshot of transurethral resection in the UK audit (STUKA). BJU INTERNATIONAL, Vol. 109 (pp 34-34)
- Hypoxia regulated miRNAs in bladder cancer. BJU INTERNATIONAL, Vol. 109 (pp 25-25)
- 1058 DIFFERENCES IN DNA METHYLATION PATTERN OF PRIMARY BLADDER TUMOURS CORRELATE WITH THEIR METASTATIC POTENTIAL. Journal of Urology, Vol. 187(4S)
- The utilisation of microrna in urine samples as a potential diagnostic and prognostic biomarker in bladder cancer. BRITISH JOURNAL OF SURGERY, Vol. 98(6) (pp E1-E2)
- Role of expression of microrna machinery in bladder cancer. BRITISH JOURNAL OF SURGERY, Vol. 98(6) (pp E2-E2)
- PREOPERATIVE HYPERGLYCEMIA AND DIABETES AS RISK FACTORS FOR ANASTOMOTIC LEAK FOLLOWING COLECTOMY: ANALYSIS FROM THE MICHIGAN SURGICAL QUALITY COLLABORATIVE (MSQC).. DISEASES OF THE COLON & RECTUM, Vol. 54(5) (pp E43-E44)
- 869 A SPECIFIC DNA METHYLATION PATTERN DISTINGUISHES BETWEEN METASTATIC AND NON-METASTATIC BLADDER CANCERS. Journal of Urology, Vol. 185(4S)
- Urinary MicroRNAs as a diagnostic biomarker in bladder cancer. BRITISH JOURNAL OF SURGERY, Vol. 98 (pp 52-52)
- Optimisation of microRNA extraction from urine samples with a view for a diagnostic and prognostic test for bladder cancer. BJU INTERNATIONAL, Vol. 106(1) (pp 55-55)
- Differential expression of microRNA processing machinery in Urothelial Carcinoma. BJU INTERNATIONAL, Vol. 106(1) (pp 54-54)
- Molecular diagnosis of localized prostate cancer by quantitative methylation-specific PCR gene patterns in urine cells obtained by prostate massage. JOURNAL OF UROLOGY, Vol. 177(4) (pp 95-95)
- Development of a prognostic marker panel in bladder cancer using aberrant promoter methylation. JOURNAL OF UROLOGY, Vol. 177(4) (pp 295-296)
- Compared performance of microsatellite and methylation urinalysis in predicting recurrence in transitional cell carcinoma and definition of a diagnostic panel of markers by bayesian network analysis. JOURNAL OF UROLOGY, Vol. 177(4) (pp 296-296)
- Artificial intelligence re-analysis of gene array data identifies novel markers of urothelial cancer progression. JOURNAL OF UROLOGY, Vol. 177(4) (pp 297-298)
- FGFR3 mutations have different effects on disease course in tumors from the bladder, ureter, and renal pelvis. CANCER RESEARCH, Vol. 66(8)
- FGFR3 mutations in upper urinary tract tumors are independent from microsatellite instability and associated with favorable outcome and a lower rate of bladder cancer recurrence. CANCER RESEARCH, Vol. 66(8)
- A gene promoter hypermethylation panel to detect transitional cell carcinoma (TCC) of the bladder. CANCER RESEARCH, Vol. 66(8)
- Epigenetic changes in urothelial cancer: A feature of the invasive phenotype and a novel therapeutic target. JOURNAL OF UROLOGY, Vol. 175(4) (pp 197-197)
- Artificial intelligence technique for gene expression profiling of urinary bladder cancer. 2006 3RD INTERNATIONAL IEEE CONFERENCE INTELLIGENT SYSTEMS, VOLS 1 AND 2 (pp 634-639)
- beta-dystroglycan is constitutively expressed at the intercellular junctions of epithelial cells and this expression is frequently absent in common cancers. JOURNAL OF PATHOLOGY, Vol. 205 (pp 6-6)
- Proteomic analysis of voided urine following prostatic massage reveals tumour specific alterations. JOURNAL OF UROLOGY, Vol. 171(4) (pp 286-286)
- Increasing aircraft survivability through explosives detection. Aircraft Engineering, Technology, and Operations Congress
- Shorter hospital stay with robotic surgery versus open surgery in bladder cancer. Medicom Conference Report EAU 2022, 1 July 2022 - 1 July 2022.
Posters
- PD42-02 RESULTS OF THE INTRACORPOREAL ROBOTIC VS OPEN CYSTECTOMY (IROC) MULTI-CENTRE RANDOMISED TRIAL.
- Comparing the ability of wearable devices and CPET to predict major complications following radical cystectomy.
Preprints
- Analysis of the Distal Urinary Tract in Larval and Adult Zebrafish Reveals Unrecognized Homology to the Human System, Cold Spring Harbor Laboratory.
- Domiciliary recovery after medicalization pathway (DREAMPath): a protocol for a prospective observational study to measure patient compliance with remote monitoring following discharge from hospital after major surgery. (Preprint), JMIR Publications Inc..
- Teaching activities
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James teaches undergraduate medical students weekly and organises various uro-oncology study days for post-graduate urologists and surgeons. James is an educational supervisor to three trainee urologist and PhD mentor to 8 students.
- Professional activities and memberships
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James is a member of the NCRI-CSG for Bladder and Kidney cancer, the EAU Scientific Congress Office and specialises in Uro-Oncology. He was part of the NICE Bladder Cancer Guideline development panel.
James is on the Trial Steering Groups for numerous trials including i). Life after prostate cancer (Funded by Prostate cancer UK and Movember – see https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30780-0/fulltext). ii). VANCE01 - A randomized phase I study to determine the safety and immunogenicity of ChAd-MVA vaccination compared to MVA alone with and without low dose cyclophosphamide in low and intermediate risk localised prostate cancer (Funded by European Union – see https://jitc.bmj.com/content/8/1/e000928), iii). POUT - A phase III randomised trial of peri-operative chemotherapy versus surveillance in upper tract urothelial cancer (Funded by CRUK – see https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30415-3/fulltext), iv). BladderPath - Image directed Redesign of Bladder Cancer Treatment Pathways (Funded by NIHR-HTA – see https://www.europeanurology.com/article/S0302-2838(21)00141-X/fulltext), and v). CALIBER - A phase II randomised feasibility study of Chemoresection and surgicAl management in Low rIsk non muscle invasive Bladder cancer (Funded by CRUK – see https://bjui-journals.onlinelibrary.wiley.com/doi/full/10.1111/bju.15038).