Dr Vee San Cheong

School of Mechanical, Aerospace and Civil Engineering

Lecturer in Biomechanics

v.cheong@sheffield.ac.uk
+44 114 2220159

Pam Liversidge Building

Full contact details

Dr Vee San Cheong
School of Mechanical, Aerospace and Civil Engineering
Pam Liversidge Building
Mappin Street
Sheffield
S1 3JD

Profile

I am a bioengineer by training, graduating with a BEng (Hons) first class and a minor in Economics from Nanyang Technological University (NTU), Singapore.

I completed my PhD in Bioengineering from Imperial College London, and my thesis won the runners’ up prize for the JRI Best Medical Engineering PhD from the Institution of Mechanical Engineers (IMechE).

I then spent time as a postdoctoral research associate at UCL/Royal National Orthopaedic Hospital, University of Sheffield and Singapore-ETH Centre (ETH Singapore), before taking up my current position.

I have developed innovative methodologies and predictive models to understand implant success/failure, assess fracture risk across diverse populations, and to optimise treatment interventions in orthopaedic diseases.

My work has won several awards including the Insigneo Post Doc Bridging Fund and the British Orthopaedic Research Society (BORS) Young Investigators’ Award.

Research interests

My research interests include multiscale modelling of musculoskeletal tissues in response to novel biomaterials, and optimisation of implant designs and treatment interventions for orthopaedic diseases, in collaboration with other academic, clinical and industrial partners.

I use a multidisciplinary approach that combines imaging, mechanical testing, biological experiments and computational (hybrid mechanistic-artificial intelligence) modelling.

Publications

Journal articles

Moraiti S, Cheong VS, Dall’Ara E, Kadirkamanathan V & Bhattacharya P (2024) A novel framework for elucidating the effect of mechanical loading on the geometry of ovariectomized mouse tibiae using principal component analysis. Frontiers in Bioengineering and Biotechnology, 12. View this article in WRRO
Zou Z, Cheong VS & Fromme P (2024) Bone remodelling prediction using mechanical stimulus with bone connectivity theory in porous implants. Journal of the Mechanical Behavior of Biomedical Materials, 153, 106463-106463.
Farage-O’Reilly SM, Cheong VS, Pickering E, Pivonka P, Bellantuono I, Kadirkamanathan V & Dall’Ara E (2024) The loading direction dramatically affects the mechanical properties of the mouse tibia. Frontiers in Bioengineering and Biotechnology, 12. View this article in WRRO
Roberts BC, Cheong VS, Oliviero S, Arredondo Carrera HM, Wang N, Gartland A & Dall'Ara E (2024) Combining PTH(1‐34) and mechanical loading has increased benefit to tibia bone mechanics in ovariectomised mice. Journal of Orthopaedic Research, 42(6), 1254-1266. View this article in WRRO
Omer M, Ngo C, Ali H, Orlovskaya N, Cheong VS, Ballesteros A, Garner MT, Wynn A, Martyniak K, Wei F , Collins BE et al (2023) The effect of omega-9 on bone viscoelasticity and strength in an ovariectomized diet-fed murine model. Nutrients, 15(5).
Wei F, Neal CJ, Sakthivel TS, Fu Y, Omer M, Adhikary A, Ward S, Ta KM, Moxon S, Molinari M , Asiatico J et al (2023) A novel approach for the prevention of ionizing radiation-induced bone loss using a designer multifunctional cerium oxide nanozyme. Bioactive Materials, 21, 547-565.
Omer M, Ali H, Orlovskaya N, Ballesteros A, Cheong VS, Martyniak K, Wei F, Collins BE, Yarmolenko SN, Asiatico J , Kinzel M et al (2022) Omega-9 modifies viscoelasticity and augments bone strength and architecture in a high-fat diet-fed murine model. Nutrients, 14(15).
Oliviero S, Cheong VS, Roberts BC, Orozco Diaz CA, Griffiths W, Bellantuono I & Dall’Ara E (2022) Reproducibility of densitometric and biomechanical assessment of the mouse tibia from in vivo micro-CT images. Frontiers in Endocrinology, 13. View this article in WRRO
Cheong VS, Roberts BC, Kadirkamanathan V & Dall'Ara E (2021) Positive interactions of mechanical loading and PTH treatments on spatio-temporal bone remodelling.. Acta Biomater, 136, 291-305. View this article in WRRO
Liu Z, Tamaddon M, Chen S-M, Wang H, Cheong VS, Gang F, Sun X & Liu C (2021) Determination of an initial stage of the bone tissue ingrowth into titanium matrix by cell adhesion model. Frontiers in Bioengineering and Biotechnology, 9. View this article in WRRO
Cheong VS, Kadirkamanathan V & Dall’Ara E (2021) The role of the loading condition in predictions of bone adaptation in a mouse tibial loading model. Frontiers in Bioengineering and Biotechnology, 9. View this article in WRRO
Roberts B, Cheong VS, Oliviero S, Carrera HA, Wang N, Gartland A & Dall'Ara E (2021) Oral Communications & Poster Abstracts. JBMR PLUS, 5.
Cheong VS, Roberts BC, Kadirkamanathan V & Dall'Ara E (2020) Bone remodelling in the mouse tibia is spatio-temporally modulated by oestrogen deficiency and external mechanical loading: A combined in vivo/in silico study. Acta Biomaterialia, 116, 302-317. View this article in WRRO
Cheong VS, Campos Marin A, Lacroix D & Dall’Ara E (2020) A novel algorithm to predict bone changes in the mouse tibia properties under physiological conditions. Biomechanics and Modeling in Mechanobiology, 19(3), 985-1001. View this article in WRRO
Mumith A, Cheong VS, Fromme P, Coathup MJ & Blunn GW (2020) The effect of strontium and silicon substituted hydroxyapatite electrochemical coatings on bone ingrowth and osseointegration of selective laser sintered porous metal implants.. PLoS One, 15(1).

Chapters

San Cheong V, Palanca M & Dall'Ara E (2023) Bone strength, bone remodeling, and Biomechanics of fracture, Digital Human Modeling and Medicine (pp. 515-546). Elsevier
Dall’Ara E & Cheong VS (2022) Bone biomechanics, Human Orthopaedic Biomechanics (pp. 97-120). Elsevier

Datasets

Preprints

Roberts BC, Cheong VS, Oliviero S, Carrera HMA, Wang N, Gartland A & Dall’Ara E (2022) Combining PTH(1-34) and mechanical loading has increased benefit to tibia bone mechanics in ovariectomised mice, Research Square Platform LLC.