Professor Jim Wild
PhD
Clinical Medicine, School of Medicine and Population Health
Professor of Magnetic Resonance Physics, Executive Director of Insigneo Institute
+44 114 215 9141
Full contact details
Clinical Medicine, School of Medicine and Population Health
Polaris
18 Claremont Crescent
Sheffield
S10 2TA
- Profile
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For enquiries, please contact - SMPH-West-Operational@sheffield.ac.uk
I joined the University of Sheffield in 2000 to set up the technology for Hyperpolarised gas lung Magnetic Resonance Imaging (MRI).
- Postdoctoral researcher at the NMR group University of Alberta (1998-2000) -high field strength imaging and spectroscopy methods
- PhD was in 1H MR spectroscopy at the University of Edinburgh (1995-1998)
- Research interests
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My research is the physics and engineering and clinical applications of hyperpolarised gas (3He and 129Xe) and proton MRI in the lungs and pulmonary vasculature.
Physics and engineering projects include:
- rapid acquisition methods for imaging of inhaled hyperpolarised gases using compressed sensing, steady state free precession and parallel imaging.
- Techniques for simultaneous imaging of 1H, 3He and 129Xe in the lungs.
- RF coil hardware engineering for 3He and 129Xe lung MRI.
- 3He and 129Xe MRI at different magnetic field strengths.
- Spin exchange optical pumping physics for polarisation of 3He and 129Xe.
- Measuring and modelling gas flow and diffusion in the lungs; physiological models of alveolar geometry and gas exchange.
These technical developments have made a clinical impact, we have performed the first clinical studies in the UK with hyperpolarised 3He and 129Xe gas MRI. Our research has demonstrated the role of these pulmonary MRI methods in Asthma, COPD, Cystic Fibrosis, Interstitial Lung Disease, Lung cancer and Pulmonary Hypertension. Using hyperpolarised gas and proton lung MRI as markers we are evaluating novel pulmonary therapies in collaboration with pharmaceutical companies.
Our lung imaging methods and models are the basis of patient specific in-silico models of lung disease – insigneo. Our pulmonary imaging methods have made a clinical impact on NHS radiological practice in the diagnosis and management of patients from the Sheffield Pulmonary Vascular Disease Unit. We are now a national and international referral centre for Clinical Pulmonary Imaging.
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Magnetic Resonance Imaging in the Prognostic Evaluation of Patients with Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 196(2). View this article in WRRO
- Prognostic value of cardiovascular magnetic resonance imaging measurements corrected for age and sex in idiopathic pulmonary arterial hypertension.. Circ Cardiovasc Imaging, 7(1), 100-106.
- (3)He pO2 mapping is limited by delayed-ventilation and diffusion in chronic obstructive pulmonary disease.. Magn Reson Med, 71(3), 1172-1178. View this article in WRRO
- Optimized production of hyperpolarized 129Xe at 2 bars for in vivo lung magnetic resonance imaging. Journal of Applied Physics, 113(4).
- Simultaneous imaging of lung structure and function with triple-nuclear hybrid MR imaging.. Radiology, 267(1), 251-255.
- The influence of lung airways branching structure and diffusion time on measurements and models of short-range 3He gas MR diffusion.. J Magn Reson, 225, 102-113.
- Incorporation of prior knowledge in compressed sensing for faster acquisition of hyperpolarized gas images.. Magn Reson Med, 69(2), 360-369.
- Lung morphology assessment with balanced steady-state free precession MR imaging compared with CT.. Radiology, 263(2), 569-577.
- Hyperpolarized 129Xe gas lung MRI-SNR and T2* comparisons at 1.5 T and 3 T.. Magn Reson Med, 68(6), 1900-1904.
- Direct visualisation of collateral ventilation in COPD with hyperpolarised gas MRI.. Thorax, 67(7), 613-617. View this article in WRRO
- Enhancement of 129Xe polarization by off-resonant spin exchange optical pumping. Journal of Applied Physics, 108(6). View this article in WRRO
Other
All publications
Journal articles
- Measurement and modeling of xenon gas transfer in the human brain with 1H and hyperpolarized 129Xe MRI. Journal of Magnetic Resonance Open, 21, 100166-100166.
- Non-local impact of distal airway constrictions on patterns of inhaled particle deposition. Royal Society Open Science, 11(11).
- Mapping the amplitude and phase of dissolved 129 Xe red blood cell signal oscillations with keyhole spectroscopic lung imaging. Magnetic Resonance in Medicine. View this article in WRRO
- Compressed sensing reconstruction for high-SNR, rapid dissolved 129Xe gas exchange MRI. Magnetic Resonance in Medicine. View this article in WRRO
- The spectrum of systemic sclerosis-associated pulmonary hypertension: Insights from the ASPIRE registry. The Journal of Heart and Lung Transplantation, 43(10), 1629-1639. View this article in WRRO
- Improving Xenon‐129 lung ventilation image SNR with deep‐learning based image reconstruction. Magnetic Resonance in Medicine.
- Diagnostic utility of electrocardiogram for screening of cardiac injury on cardiac magnetic resonance in post-hospitalised COVID-19 patients: A prospective multicenter study. International Journal of Cardiology, 132415-132415.
- Cognitive and psychiatric symptom trajectories 2–3 years after hospital admission for COVID-19: a longitudinal, prospective cohort study in the UK. The Lancet Psychiatry.
- CTEPH is an uncommon complication of COVID-19: UK national surveillance and observational screening cohort studies. European Respiratory Journal, 2301742-2301742.
- Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airway diseases in the UK: a multicentre, longitudinal cohort study – PHOSP-COVID. ERJ Open Research, 10(4). View this article in WRRO
- Association of risk assessment at diagnosis with healthcare resource utilization and health‐related quality of life outcomes in pulmonary arterial hypertension. Pulmonary Circulation, 14(3). View this article in WRRO
- Long COVID and cardiovascular disease: a prospective cohort study. Open Heart, 11(1), e002662-e002662.
- Age, sex, and lung volume dependence of dissolved xenon‐129 MRI gas exchange metrics. Magnetic Resonance in Medicine. View this article in WRRO
- 1596: The impact of dosimetric features on interpretable overall survival prediction in NSCLC radiotherapy. Radiotherapy and Oncology, 194, S4488-S4492.
- 1614: MRI V/Q for assessing radiation-induced changes in regional lung function in lung cancer patients. Radiotherapy and Oncology, 194, S5062-S5066.
- Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease. Nature Immunology, 25(4), 607-621. View this article in WRRO
- Review of Hyperpolarized Pulmonary Functional 129Xe MR for Long‐COVID. Journal of Magnetic Resonance Imaging, 59(4).
- Improving Prognostication in Pulmonary Hypertension Using AI-quantified Fibrosis and Radiologic Severity Scoring at Baseline CT. Radiology, 310(2).
- Risk assessment and real-world outcomes in chronic thromboembolic pulmonary hypertension: insights from a UK pulmonary hypertension referral service. BMJ Open, 14(1). View this article in WRRO
- Explainable deep learning-based survival prediction for non-small cell lung cancer patients undergoing radical radiotherapy. Radiotherapy and Oncology, 110084-110084.
- Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury. Brain Communications, 6(1).
- Lung functional imaging. Breathe, 19(3), 220272-220272.
- Long COVID research: an update from the PHOSP-COVID Scientific Summit. The Lancet Respiratory Medicine, 11(11), e93-e94.
- Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study. The Lancet Respiratory Medicine.
- Initial feasibility and challenges of hyperpolarized
129Xe MRI in neonates with bronchopulmonary dysplasia. Magnetic Resonance in Medicine. - PhysVENeT: a physiologically-informed deep learning-based framework for the synthesis of 3D hyperpolarized gas MRI ventilation. Scientific Reports, 13.
- Artificial Intelligence framework with traditional computer vision and deep learning approaches for optimal automatic segmentation of left ventricle with scar. Artificial Intelligence in Medicine, 102610-102610.
- Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls. The Lancet Regional Health - Europe, 29. View this article in WRRO
- Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study. The Lancet Respiratory Medicine.
- Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. Chest.
- A hybrid model‐ and deep learning‐based framework for functional lung image synthesis from multi‐inflation CT and hyperpolarized gas MRI. Medical Physics.
- Pulmonary Artery Strain Predicts Prognosis in Pulmonary Arterial Hypertension. JACC: Cardiovascular Imaging.
- Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study. eClinicalMedicine, 57, 101896-101896.
- Quantifying Myocardial Blood Flow and Resistance Using 4D-Flow Cardiac Magnetic Resonance Imaging. Cardiology Research and Practice, 2023, 1-7.
- Functional imaging in asthma and COPD: design of the NOVELTY ADPro substudy. ERJ Open Research, 9(1).
- Semi-automatic thresholding of RV trabeculation improves repeatability and diagnostic value in suspected pulmonary hypertension. Frontiers in Cardiovascular Medicine, 9.
- Investigating rubidium density and temperature distributions in a high-throughput 129Xe-Rb spin-exchange optical pumping polarizer. Molecules, 28(1).
- SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination. eBioMedicine, 87.
- Automatic development of 3D anatomical models of border zone and core scar regions in the left ventricle. Computerized Medical Imaging and Graphics, 103, 102152-102152.
- A dual-channel deep learning approach for lung cavity estimation from hyperpolarized gas and proton MRI. Journal of Magnetic Resonance Imaging.
- Imaging biomarkers of lung ventilation in interstitial lung disease from 129Xe and oxygen enhanced 1H MRI. Magnetic Resonance Imaging.
- Mapping alveolar oxygen partial pressure in COPD using hyperpolarized helium-3: the multi-ethnic study of atherosclerosis (MESA) COPD study. Tomography, 8(5), 2268-2284.
- Validation of Artificial Intelligence Cardiac MRI Measurements: Relationship to Heart Catheterization and Mortality Prediction. Radiology, 304(3), E56-E56.
- Image phenotyping of preterm-born children using hyperpolarised 129Xe lung MRI and multiple-breath washout. American Journal of Respiratory and Critical Care Medicine. View this article in WRRO
- Big data and long COVID. The Lancet Digital Health, 4(7), e477-e477.
- Quantification of lung ventilation defects on hyperpolarized MRI: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD study. Magnetic Resonance Imaging, 92, 140-149.
- Large-scale investigation of deep learning approaches for ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI. Scientific Reports, 12(1). View this article in WRRO
- Validation of Artificial Intelligence Cardiac MRI Measurements: Relationship to Heart Catheterization and Mortality Prediction.. Radiology, 212929.
- Lung abnormalities depicted with hyperpolarized Xenon MRI in patients with Long COVID. Radiology. View this article in WRRO
- Model-based Bayesian inference of the ventilation distribution in patients with cystic fibrosis from multiple breath washout, with comparison to ventilation MRI. Respiratory Physiology & Neurobiology, 302.
- Right ventricular remodelling in pulmonary arterial hypertension predicts treatment response.. Heart.
- Cardiac magnetic resonance identifies raised left ventricular filling pressure: prognostic implications.. Eur Heart J.
- Machine learning cardiac-MRI features predict mortality in newly diagnosed pulmonary arterial hypertension. European Heart Journal - Digital Health.
- Validation of aortic valve pressure gradient quantification using semi-automated 4D flow CMR pipeline. BMC Research Notes, 15(1).
- Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study. The Lancet Respiratory Medicine. View this article in WRRO
- Training and clinical testing of artificial intelligence derived right atrial cardiovascular magnetic resonance measurements. Journal of Cardiovascular Magnetic Resonance, 24(1).
- A dual center and dual vendor comparison study of automated perfusion‐weighted phase‐resolved functional lung magnetic resonance imaging with dynamic contrast‐enhanced magnetic resonance imaging in patients with cystic fibrosis. Pulmonary Circulation, 12(2).
- Prematurity-associated lung disease: looking beyond bronchopulmonary dysplasia. The Lancet Respiratory Medicine.
- Hyperpolarized 129Xe imaging of the brain : achievements and future challenges. Magnetic Resonance in Medicine. View this article in WRRO
- Effect of indacaterol/glycopyrronium on ventilation and perfusion in COPD: a randomized trial. Respiratory Research, 23(1). View this article in WRRO
- Computed tomography lung parenchymal descriptions in routine radiological reporting have diagnostic and prognostic utility in patients with idiopathic pulmonary arterial hypertension and pulmonary hypertension associated with lung disease.. ERJ Open Res, 8(1).
- Mitral regurgitation quantification by cardiac magnetic resonance imaging (MRI) remains reproducible between software solutions. Wellcome Open Research, 6, 253-253.
- Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood. Nature Communications, 12. View this article in WRRO
- Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.. The Lancet Respiratory Medicine. View this article in WRRO
- Mitral regurgitation quantification by cardiac magnetic resonance imaging (MRI) remains reproducible between software solutions. Wellcome Open Research, 6, 253.
- MA-SOCRATIS: An automatic pipeline for robust segmentation of the left ventricle and scar. Computerized Medical Imaging and Graphics, 93, 101982-101982.
- Brain energy metabolism in ALS: A phosphorus-31 magnetic resonance spectroscopy study. Journal of the Neurological Sciences, 429, 119412.
- MA06.03 Deep Learning-Based Survival Prediction for Non-Small Cell Lung Cancer Patients Undergoing Radical Radiotherapy. Journal of Thoracic Oncology, 16(10), S902-S903.
- Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID). BMJ Open Respiratory Research, 8(1). View this article in WRRO
- Protocols for multi-site trials using hyperpolarized 129 Xe MRI for imaging of ventilation, alveolar-airspace size, and gas exchange: A position paper from the 129 Xe MRI clinical trials consortium.. Magn Reson Med.
- High interstudy repeatability of automatic deep learnt biventricular CMR measurements. European Heart Journal - Cardiovascular Imaging, 22(Supplement_2).
- Fully automated CMR derived stroke volume correlates with right heart catheter measurements in patients with suspected pulmonary hypertension. European Heart Journal - Cardiovascular Imaging, 22(Supplement_2).
- Myocardial T1-mapping and extracellular volume in pulmonary arterial hypertension : a systematic review and meta-analysis. Magnetic Resonance Imaging, 79, 66-75.
- Hyperpolarized 129Xe MRI Abnormalities in Dyspneic Participants 3 Months after COVID-19 Pneumonia: Preliminary Results.. Radiology, 210033.
- Xenon MRI for Future Assessment of Lung Function and Treatment Response: A Commentary.. Journal of magnetic resonance imaging : JMRI.
- Cardiovascular magnetic resonance predicts all-cause mortality in pulmonary hypertension associated with heart failure with preserved ejection fraction. International Journal of Cardiovascular Imaging. View this article in WRRO
- Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. Genome Medicine, 13(1), 80-80. View this article in WRRO
- Deep learning in structural and functional lung image analysis.. Br J Radiol, 20201107.
- Pulmonary Hypertension in Association with Lung Disease: Quantitative CT and Artificial Intelligence to the Rescue? State-of-the-Art Review. Diagnostics, 11(4), 679.
- Correction. JACC: Cardiovascular Imaging, 14(4), 884-884.
- Left ventricular blood flow kinetic energy is associated with the six-minute walk test and left ventricular remodelling post valvular intervention in aortic stenosis. Quantitative imaging in medicine and surgery, 11(4), 1470-1482. View this article in WRRO
- MR properties of 19F C3F8 gas in the lungs of healthy volunteers: T2* and apparent diffusion coefficient at 1.5T and T2* at 3T. Magnetic Resonance in Medicine, 85(3), 1561-1570. View this article in WRRO
- Airspace Dimension Assessment (AiDA) by inhaled nanoparticles: benchmarking with hyperpolarised 129Xe diffusion-weighted lung MRI. Scientific Reports, 11.
- Reproducibility of 19F‐MR ventilation imaging in healthy volunteers. Magnetic Resonance in Medicine, 85(6), 3343-3352.
- Standard and emerging CMR methods for mitral regurgitation quantification. International Journal of Cardiology.
- Imaging of pulmonary hypertension in adults: a position paper from the Fleischner Society. European Respiratory Journal, 57(1), 2004455-2004455.
- Comparison of phase-resolved functional lung (PREFUL) MRI derived perfusion and ventilation parameters at 1.5T and 3T in healthy volunteers. PLoS ONE, 15(12).
- In Vivo Methods and Applications of Xenon-129 Magnetic Resonance. Progress in Nuclear Magnetic Resonance Spectroscopy.
- The assessment of short- and long-term changes in lung function in cystic fibrosis using 129Xe MRI. European Respiratory Journal, 56(6). View this article in WRRO
- Cardiac magnetic resonance in pulmonary hypertension - an update. Current Cardiovascular Imaging Reports, 13(12).
- Meta‐analysis of echocardiographic quantification of left ventricular filling pressure. ESC Heart Failure.
- Right Ventricular Adaptation Assessed Using Cardiac Magnetic Resonance Predicts Survival in Pulmonary Arterial Hypertension. JACC: Cardiovascular Imaging.
- Cardiac-MRI Predicts Clinical Worsening and Mortality in Pulmonary Arterial Hypertension. JACC: Cardiovascular Imaging.
- The effect of acute maximal exercise on the regional distribution of ventilation using ventilation MRI in CF. Journal of Cystic Fibrosis. View this article in WRRO
- Spectral graph theory efficiently characterizes ventilation heterogeneity in lung airway networks. Journal of the Royal Society Interface, 17(168).
- Validation of four-dimensional flow cardiovascular magnetic resonance for aortic stenosis assessment. Scientific Reports, 10(1). View this article in WRRO
- Age-associated changes in 4D flow CMR derived tricuspid valvular flow and right ventricular blood flow kinetic energy. Scientific Reports, 10(1). View this article in WRRO
- An 8-element Tx/Rx Array Utilizing MEMS Detuning Combined with 6 Rx Loops for 19F and 1H Lung Imaging at 1.5 T. Magnetic Resonance in Medicine. View this article in WRRO
- Comparison of MRI and VQ-SPECT as a Screening Test for Patients With Suspected CTEPH: CHANGE-MRI Study Design and Rationale. Frontiers in Cardiovascular Medicine, 7. View this article in WRRO
- Identification of cardiac MRI thresholds for risk stratification in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine, 201(4), 458-468. View this article in WRRO
- A machine learning cardiac magnetic resonance approach to extract disease features and automate pulmonary arterial hypertension diagnosis. European Heart Journal - Cardiovascular Imaging. View this article in WRRO
- Optimized and accelerated 19F‐MRI of inhaled perfluoropropane to assess regional pulmonary ventilation. Magnetic Resonance in Medicine, 82(4), 1301-1311. View this article in WRRO
- A magnetic resonance imaging surface coil transceiver employing a metasurface for 1.5T applications. IEEE Transactions on Medical Imaging. View this article in WRRO
- Dissolved hyperpolarized xenon‐129 MRI in human kidneys. Magnetic Resonance in Medicine, 83(1), 262-270. View this article in WRRO
- A systematic review of 4D-flow MRI derived mitral regurgitation quantification methods. Frontiers in Cardiovascular Medicine, 6. View this article in WRRO
- Express: The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry.. Pulmonary Circulation. View this article in WRRO
- Hyperpolarised xenon magnetic resonance spectroscopy for the longitudinal assessment of changes in gas diffusion in IPF. Thorax, 74(5), 500-502. View this article in WRRO
- Experimental and quantitative imaging techniques in interstitial lung disease. Thorax, 74(6), 611-619. View this article in WRRO
- EXPRESS: Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI).. Pulmonary Circulation. View this article in WRRO
- A Systematic Review of Right Ventricular Diastolic Assessment by 4D Flow CMR. BioMed Research International, 2019. View this article in WRRO
- The VAMPIRE Challenge: A Multi‐Institutional Validation Study of CT Ventilation Imaging. Medical Physics, 46(3), 1198-1217. View this article in WRRO
- New Developments in Imaging Idiopathic Pulmonary Fibrosis With Hyperpolarized Xenon Magnetic Resonance Imaging.. Journal of Thoracic Imaging, 34(2), 136-150. View this article in WRRO
- Single breath-held acquisition of co-registered 3D 129Xe lung ventilation and anatomical proton images of the human lung with compressed sensing. Magnetic Resonance in Medicine. View this article in WRRO
- Airway microstructure in idiopathic pulmonary fibrosis: Assessment at hyperpolarized 3He diffusion-weighted MRI. Radiology, 291(1). View this article in WRRO
- Assessment of brain perfusion using hyperpolarized 129Xe MRI in a subject with established stroke.. Journal of Magnetic Resonance Imaging. View this article in WRRO
- Optimization of steady‐state free precession MRI for lung ventilation imaging with 19 F C 3 F 8 at 1.5T and 3T. Magnetic Resonance in Medicine, 81(2), 1130-1142. View this article in WRRO
- Comparison of CT ventilation imaging and hyperpolarised gas MRI: effects of breathing manoeuvre.. Physics in Medicine and Biology. View this article in WRRO
- Imaging Collateral Ventilation in Patients With Advanced Chronic Obstructive Pulmonary Disease: Relative Sensitivity of 3 He and 129 Xe MRI. Journal of Magnetic Resonance Imaging, 49(4), 1195-1197. View this article in WRRO
- Comparison of in vivo lung morphometry models from 3D multiple b-value 3He and 129Xe diffusion-weighted MRI. Magnetic Resonance in Medicine. View this article in WRRO
- Diagnostic and prognostic significance of cardiovascular magnetic resonance native myocardial T1 mapping in patients with pulmonary hypertension. Journal of Cardiovascular Magnetic Resonance, 20. View this article in WRRO
- Spatial Comparison of CT-Based Surrogates of Lung Ventilation With Hyperpolarized Helium-3 and Xenon-129 Gas MRI in Patients Undergoing Radiation Therapy. International Journal of Radiation Oncology, Biology, Physics, 102(4), 1276-1286. View this article in WRRO
- Assessment of the influence of lung inflation state on the quantitative parameters derived from hyperpolarized gas lung ventilation MRI in healthy volunteers.. Journal of Applied Physiology. View this article in WRRO
- Patterns of regional lung physiology in cystic fibrosis using ventilation magnetic resonance imaging and multiple-breath washout.. European Respiratory Journal, 52(5). View this article in WRRO
- Diagnosis of Pulmonary Hypertension with Cardiac MRI: Derivation and Validation of Regression Models.. Radiology, 290(1). View this article in WRRO
- Drug-Induced Interstitial Lung Disease: A Systematic Review.. J Clin Med, 7(10). View this article in WRRO
- 129 Xe-Rb Spin-Exchange Optical Pumping with High Photon Efficiency. Physical Review Letters, 121(15). View this article in WRRO
- Identifying At-Risk Patients with Combined Pre- and Postcapillary Pulmonary Hypertension Using Interventricular Septal Angle at Cardiac MRI. Radiology, 289(1), 180120-180120. View this article in WRRO
- The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension. European Respiratory Journal, 52(3). View this article in WRRO
- Comparison of Quantitative Multiple Breath Specific Ventilation Imaging Using Co-localized 2D Oxygen Enhanced MRI and Hyperpolarized 3He MRI.. Journal of Applied Physiology. View this article in WRRO
- Magnetic resonance angiography for the primary diagnosis of pulmonary embolism: A review from the international workshop for pulmonary functional imaging. World Journal of Radiology, 10(6), 52-64. View this article in WRRO
- Pulmonary Artery Size in Interstitial Lung Disease and Pulmonary Hypertension: Association with Interstitial Lung Disease Severity and Diagnostic Utility. Frontiers in Cardiovascular Medicine, 5. View this article in WRRO
- Effect of upper airway on tracheobronchial fluid dynamics. International Journal for Numerical Methods in Biomedical Engineering, 34(9), e3112-e3112. View this article in WRRO
- CT derived left atrial size identifies left heart disease in suspected pulmonary hypertension: Derivation and validation of predictive thresholds. International Journal of Cardiology, 260, 172-177. View this article in WRRO
- Imaging Lung Function Abnormalities in Primary Ciliary Dyskinesia Using Hyperpolarized Gas Ventilation MRI. Annals of the American Thoracic Society, 15(12), 1487-1490. View this article in WRRO
- Role of Cardiac T1 Mapping and Extracellular Volume (ECV) in the Assessment of Myocardial Infarction. The Anatolian Journal of Cardiology. View this article in WRRO
- 3D phase contrast MRI in models of human airways: Validation of computational fluid dynamics simulations of steady inspiratory flow. Journal of Magnetic Resonance Imaging, 48(5), 1400-1409. View this article in WRRO
- Comparison of MEMS switches and PIN diodes for switched dual tuned RF coils. Magnetic Resonance in Medicine, 80(4), 1746-1753. View this article in WRRO
- Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5T. Journal of Magnetic Resonance Imaging, 48(3), 632-642. View this article in WRRO
- Current and emerging imaging techniques in the diagnosis and assessment of pulmonary hypertension. Expert Review of Respiratory Medicine, 12(2), 145-160. View this article in WRRO
- Longitudinal Assessment of Children with Mild CF Using Hyperpolarised Gas Lung MRI and LCI. American Journal of Respiratory and Critical Care Medicine, 197(3). View this article in WRRO
- Imaging pathophysiological changes in the lungs in IPF with xenon magnetic resonance imaging. Thorax, 73(1), 1-1. View this article in WRRO
- 3D diffusion-weighted 129 Xe MRI for whole lung morphometry. Magnetic Resonance in Medicine, 79(6), 2986-2995. View this article in WRRO
- Supine posture changes lung volumes and increases ventilation heterogeneity in cystic fibrosis. PLoS ONE, 12(11). View this article in WRRO
- Lung perfusion: MRI vs. SPECT for screening in suspected chronic thromboembolic pulmonary hypertension. Journal of Magnetic Resonance Imaging, 46(6), 1693-1697. View this article in WRRO
- Comparison of in-vivo lung morphometry models from multiple b-value diffusion-weighted MRI in healthy controls, IPF and COPD patients. European Respiratory Journal, 50(Suppl 61). View this article in WRRO
- Impact of field number and beam angle on functional image-guided lung cancer radiotherapy planning.. Physics in Medicine and Biology, 62(17), 7114-7130. View this article in WRRO
- Regional Ventilation Changes in the Lung: Treatment Response Mapping by Using Hyperpolarized Gas MR Imaging as a Quantitative Biomarker. Radiology, 284(3). View this article in WRRO
- Septal angle on MRI predicts combined pre- and post-capillary pulmonary hypertension. Clinical Radiology, 72, S1-S2.
- Imaging Human Brain Perfusion with Inhaled Hyperpolarized (129)Xe MR Imaging.. Radiology, 286(2). View this article in WRRO
- Magnetic Resonance Imaging in the Prognostic Evaluation of Patients with Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 196(2). View this article in WRRO
- Spatial fuzzy c-means thresholding for semiautomated calculation of percentage lung ventilated volume from hyperpolarized gas and (1) H MRI. Journal of Magnetic Resonance Imaging. View this article in WRRO
- The VAMPIRE Challenge: Results of An International Multi-Institutional Validation Study to Evaluate CT Ventilation Imaging Algorithms. MEDICAL PHYSICS, 44(6), 3311-3311.
- Incremental Shuttle Walking Test Distance and Autonomic Dysfunction Predict Survival in Pulmonary Arterial Hypertension. The Journal of Heart and Lung Transplantation. View this article in WRRO
- Whole lung morphometry with 3D multiple b‐value hyperpolarized gas MRI and compressed sensing. Magnetic Resonance in Medicine, 77(5), 1916-1925. View this article in WRRO
- 129 Xe chemical shift in human blood and pulmonary blood oxygenation measurement in humans using hyperpolarized 129 Xe NMR. Magnetic Resonance in Medicine, 77(4), 1399-1408. View this article in WRRO
- Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI. Thorax, 72(8), 760-762. View this article in WRRO
- Pulmonary MR angiography and perfusion imaging—A review of methods and applications. European Journal of Radiology, 86, 361-370. View this article in WRRO
- Hyperpolarized (13) C,(15) N2 -Urea MRI for assessment of the urea gradient in the porcine kidney.. Magnetic Resonance in Medicine, 76(6), 1895-1899. View this article in WRRO
- Functional Image-guided Radiotherapy Planning for Normal Lung Avoidance. Clin Oncol (R Coll Radiol), 28(11), 695-707. View this article in WRRO
- Finite element modeling of 129Xe diffusive gas exchange NMR in the human alveoli. Journal of Magnetic Resonance, 271, 21-33. View this article in WRRO
- Enhancement of radio frequency magnetic field for a 1.5 T magnetic resonance system using a high impedance surface. IET Microwaves, Antennas and Propagation, 10(13), 1378-1383. View this article in WRRO
- Chronic Obstructive Pulmonary Disease: Lobar Analysis with Hyperpolarized (129)Xe MR Imaging.. Radiology, 152299-152299. View this article in WRRO
- Multiple breath washout of hyperpolarized (129) Xe and (3) He in human lungs with three-dimensional balanced steady-state free-precession imaging.. Magn Reson Med. View this article in WRRO
- Reproducibility of quantitative indices of lung function and microstructure from 129Xe chemical shift saturation recovery (CSSR) MR spectroscopy. Magnetic Resonance in Medicine. View this article in WRRO
- Diagnosis of Pulmonary Hypertension from Magnetic Resonance Imaging–Based Computational Models and Decision Tree Analysis. Pulmonary Circulation, 6(2), 181-190. View this article in WRRO
- High resolution spectroscopy and chemical shift imaging of hyperpolarized 129Xe dissolved in the human brain in vivo at 1.5 tesla. Magnetic Resonance in Medicine, 75(6), 2227-2234. View this article in WRRO
- Pulmonary ventilation and micro-structural findings in congenital diaphragmatic hernia. Pediatric Pulmonology, 51(5), 517-524.
- RF instrumentation for same-breath triple nuclear lung MR imaging of 1 H and hyperpolarized 3 He and 129 Xe at 1.5T. Magnetic Resonance in Medicine, 75(4), 1841-1848. View this article in WRRO
- An Algorithm for the Segmentation of Highly Abnormal Hearts Using a Generic Statistical Shape Model. IEEE Transactions on Medical Imaging, 35(3), 845-859.
- Comparison of CT-based Lobar Ventilation with3He MR Imaging Ventilation Measurements. Radiology, 278(2), 585-592.
- Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension. Current Cardiovascular Imaging Reports, 8(12).
- Magnetic resonance imaging in children: common problems and possible solutions for lung and airways imaging. Pediatric Radiology, 45(13), 1901-1915. View this article in WRRO
- Observation of cardiogenic flow oscillations in healthy subjects with hyperpolarized 3 He MRI. Journal of Applied Physiology, 119(9), 1007-1014. View this article in WRRO
- Ventilation heterogeneity and the benefits and challenges of multiple breath washout testing in patients with cystic fibrosis. Paediatric Respiratory Reviews, 16, 15-18.
- Longitudinal and Transverse Right Ventricular Function in Pulmonary Hypertension: Cardiovascular Magnetic Resonance Imaging Study from the ASPIRE Registry. Pulmonary Circulation, 5(3), 557-564.
- Directing cell therapy to anatomic target sites in vivo with magnetic resonance targeting. Nature Communications, 6. View this article in WRRO
- Feasibility of human lung ventilation imaging using highly polarized naturally abundant xenon and optimized three-dimensional steady-state free precession. Magnetic Resonance in Medicine, 74(2), 346-352. View this article in WRRO
- Relaxation and exchange dynamics of hyperpolarized129Xe in human blood. Magnetic Resonance in Medicine, 74(2), 303-311.
- Experimental validation of the hyperpolarized 129 Xe chemical shift saturation recovery technique in healthy volunteers and subjects with interstitial lung disease. Magnetic Resonance in Medicine, 74(1), 196-207. View this article in WRRO
- In vivo measurement of gas flow in human airways with hyperpolarized gas MRI and compressed sensing.. Magn Reson Med, 73(6), 2255-2261. View this article in WRRO
- Right Ventricular Sex Differences in Patients with Idiopathic Pulmonary Arterial Hypertension Characterised by Magnetic Resonance Imaging: Pair-Matched Case Controlled Study. PLOS ONE, 10(5), e0127415-e0127415. View this article in WRRO
- CT features of pulmonary arterial hypertension and its major subtypes: a systematic CT evaluation of 292 patients from the ASPIRE Registry. Thorax, 70(4), 382-387. View this article in WRRO
- Respiratory tract exacerbations revisited: Ventilation, inflammation, perfusion, and structure (VIPS) monitoring to redefine treatment. Pediatric Pulmonology, 50(S40), S57-S65.
- Dedicated receiver array coil for1H lung imaging with same-breath acquisition of hyperpolarized3He and129Xe gas. Magnetic Resonance in Medicine, 74(1), 291-299.
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- Detection of radiation-induced lung injury in non-small cell lung cancer patients using hyperpolarized helium-3 magnetic resonance imaging. Radiotherapy and Oncology, 97(2), 244-248.
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- Slice profile effects in 2D slice-selective MRI of hyperpolarized nuclei.. J Magn Reson, 202(2), 180-189.
- Assessment of hyperpolarized 3He lung MRI for regional evaluation of interventional therapy: a pilot study in pediatric cystic fibrosis.. J Magn Reson Imaging, 30(5), 981-988.
- Functional image-based radiotherapy planning for non-small cell lung cancer: A simulation study. RADIOTHER ONCOL, 93(1), 32-36. View this article in WRRO
- Ventricular mass index correlates with pulmonary artery pressure and predicts survival in suspected systemic sclerosis-associated pulmonary arterial hypertension.. Rheumatology (Oxford), 48(9), 1137-1142.
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- Rapid Prototyping Raw Models on the Basis of High Resolution Computed Tomography Lung Data for Respiratory Flow Dynamics. ACAD RADIOL, 16(4), 495-498.
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- Asymmetric quadrature split birdcage coil for hyperpolarized He-3 lung MRI at 1.5T. MAGN RESON MED, 60(2), 431-438.
- Strongly coupled versus uncoupled spin response to radio frequency interference effects: application to glutamate and glutamine in spectroscopic imaging. NMR BIOMED, 21(4), 402-409.
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- Design and evaluation of a low field system for hyperpolarized 3-He gas imaging of neonatal lungs. CONCEPT MAGN RESON B, 31B(4), 209-217.
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- Feasibility of image registration and intensity-modulated radiotherapy planning with hyperpolarized helium-3 magnetic resonance imaging for non-small-cell lung cancer.. Int J Radiat Oncol Biol Phys, 68(1), 273-281.
- Assessment of lung disease in children with cystic fibrosis using hyperpolarized 3-Helium MRI: comparison with Shwachman score, Chrispin-Norman score and spirometry.. Eur Radiol, 17(4), 1018-1024.
- Radiation-damping effects in a birdcage resonator with hyperpolarised 3He gas NMR at 1.5 T.. J Magn Reson, 185(1), 164-172.
- Rapid lung volumetry using ultrafast dynamic magnetic resonance imaging during forced vital capacity maneuver: correlation with spirometry.. Invest Radiol, 42(1), 37-41.
- Steady-state free precession with hyperpolarized 3He: experiments and theory.. J Magn Reson, 183(1), 13-24.
- Combined simulated annealing and Shinnar-Le Roux pulse design of slice-multiplexed RF pulses for multi-slice imaging.. J Magn Reson, 182(1), 133-142.
- Simultaneous parallel inclined readout image technique.. Magn Reson Imaging, 24(5), 557-562.
- Parallel imaging of hyperpolarized helium-3 with simultaneous slice excitation.. Magn Reson Med, 55(2), 258-262.
- Hyperpolarized 3helium magnetic resonance ventilation imaging of the lung in cystic fibrosis: Comparison with high resolution CT and spirometry. European Radiology, 16(11), 2483-2490.
- Simultaneous multislice imaging with slice-multiplexed RF pulses.. Magn Reson Med, 54(4), 755-760.
- Quantitative analysis of regional airways obstruction using dynamic hyperpolarized 3He MRI-preliminary results in children with cystic fibrosis.. J Magn Reson Imaging, 22(3), 420-426.
- The effects of dehydration on brain volume -- preliminary results.. Int J Sports Med, 26(6), 481-485.
- Method of generalized projections algorithm for image-based reduction of artifacts in radial imaging.. Magn Reson Med, 54(1), 246-250.
- Emphysematous changes and normal variation in smokers and COPD patients using diffusion 3He MRI.. Eur J Radiol, 54(3), 352-358.
- 3D volume-localized pO2 measurement in the human lung with 3He MRI.. Magn Reson Med, 53(5), 1055-1064.
- Measurements and modeling of long range 3He diffusion in the lung using a "slice-washout" method.. J Magn Reson, 174(1), 28-33.
- Combined helium-3/proton magnetic resonance imaging measurement of ventilated lung volumes in smokers compared to never-smokers.. J Magn Reson Imaging, 21(4), 365-369.
- Functional MRI of the lung using hyperpolarized 3-helium gas.. J Magn Reson Imaging, 20(4), 540-554.
- Finite-difference simulations of 3He diffusion in 3D alveolar ducts: comparison with the "cylinder model".. Magn Reson Med, 52(4), 917-920.
- Comparison between 2D and 3D gradient-echo sequences for MRI of human lung ventilation with hyperpolarized 3He.. Magn Reson Med, 52(3), 673-678.
- MRI of helium-3 gas in healthy lungs: posture related variations of alveolar size.. J Magn Reson Imaging, 20(2), 331-335.
- Investigating 3He diffusion NMR in the lungs using finite difference simulations and in vivo PGSE experiments.. J Magn Reson, 167(1), 1-11.
- Strategy for the Spectral Filtering of Myo-Inositol and Other Strongly Coupled Spins. Magnetic Resonance in Medicine, 51(2), 263-272.
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- Hyperpolarized 3-helium MR imaging of the lungs: testing the concept of a central production facility.. Eur Radiol, 13(12), 2583-2586.
- Neurovascular MRI with dynamic contrast-enhanced subtraction angiography.. Neuroradiology, 45(12), 843-850.
- MRI for the diagnosis of pulmonary embolism.. J Magn Reson Imaging, 18(6), 627-640.
- Assessment and compensation of susceptibility artifacts in gradient echo MRI of hyperpolarized 3He gas.. Magn Reson Med, 50(2), 417-422.
- Functional magnetic resonance imaging of the lung.. Br J Anaesth, 91(1), 16-30.
- B1AC-MAMBA: B1 array combined with multiple-acquisition micro B0 array parallel magnetic resonance imaging.. Magn Reson Med, 49(6), 1196-1200.
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- Multiple gradient echo sequence optimized for rapid, single-scan mapping of R(2)(*) at high B0.. Magn Reson Med, 48(5), 867-876.
- Traumatic brain injury and subarachnoid hemorrhage: in vivo occult pathology demonstrated by magnetic resonance spectroscopy may not be "ischaemic". A primary study and review of the literature.. Acta Neurochir (Wien), 144(9), 853-862.
- MR imaging of the lungs with hyperpolarized helium-3 gas transported by air.. Phys Med Biol, 47(13), N185-N190.
- k-space filtering in 2D gradient-echo breath-hold hyperpolarized 3He MRI: spatial resolution and signal-to-noise ratio considerations.. Magn Reson Med, 47(4), 687-695.
- N-acetylaspartate distribution in proton spectroscopic images of ischemic stroke: relationship to infarct appearance on T2-weighted magnetic resonance imaging.. Stroke, 31(12), 3008-3014.
- Quantitative head injury assessment: Magnetic resonance spectroscopy and intensive care management during MR. Clinical Intensive Care, 11(4), 187-193.
- Accuracy of a miniature intracranial pressure monitor, its function during magnetic resonance scanning, and assessment of image artifact generation.. Neurosurgery, 45(1), 188-192.
- 1H spectroscopic imaging of acute head injury--evidence of diffuse axonal injury.. MAGMA, 8(2), 109-115.
- Artifacts introduced by zero order phase correction in proton NMR spectroscopy and a method of elimination by phase filtering.. J Magn Reson, 137(2), 430-436.
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- In vivo lactate editing in single voxel proton spectroscopy and proton spectroscopic imaging by homonuclear polarization transfer. Magnetic Resonance Imaging, 17(1), 131-139.
- USING AN ICP MONITOR DURING MR IMAGING. Journal of Neurosurgical Anesthesiology, 10(4), 295-295.
- ACCURATE BRAIN INJURY DIAGNOSIS USING CHEMICAL SHIFT MAGNETIC RESONANCE IMAGING IN ACUTE BRAIN INJURY. Journal of Neurosurgical Anesthesiology, 10(4), 294-294.
- Studies of acute ischemic stroke with proton magnetic resonance spectroscopy: relation between time from onset, neurological deficit, metabolite abnormalities in the infarct, blood flow, and clinical outcome.. Stroke, 29(8), 1618-1624.
- A systematic study of the lactate lineshape in PRESS-localized proton spectroscopy.. Magn Reson Med, 40(1), 72-78.
- Normalisation of metabolite images in 1H NMR spectroscopic imaging.. Magn Reson Imaging, 15(9), 1057-1066.
- Calculations and experimental studies of the lineshape of the lactate doublet in PRESS-localized 1H MRS.. Magn Reson Med, 38(3), 415-419.
- A framework for modelling whole-lung and regional TLCOusing hyperpolarised129Xe lung MRI. ERJ Open Research, 00442-2024.
- State of the art review | Advances in COPD imaging using CT and MRI: Linkage with lung physiology and clinical outcomes. European Respiratory Journal, 2301010-2301010.
- Systematic pulmonary embolism follow-up increases diagnostic rates of chronic thromboembolic pulmonary hypertension and identifies less severe disease: results from the ASPIRE Registry. European Respiratory Journal, 2300846-2300846.
- Unsupervised machine learning to investigate trajectory patterns of COVID-19 symptoms and physical activity measured via the MyHeart Counts App and smart devices. npj Digital Medicine, 6(1).
- Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study. International Journal of Epidemiology.
- Voxel-Wise Comparison of Co-Registered Quantitative CT and Hyperpolarised Gas Diffusion-Weighted MRI Measurements in IPF. Diagnostics, 13(23), 3497-3497.
- The Left Atrial Area Derived Cardiovascular Magnetic Resonance Left Ventricular Filling Pressure Equation Shows Superiority over Integrated Echocardiography. Medicina, 59(11), 1952-1952.
- Multicenter Standardization of Phase‐Resolved Functional Lung
MRI in Patients With Suspected Chronic Thromboembolic Pulmonary Hypertension. Journal of Magnetic Resonance Imaging. - A Framework for Predicting X-Nuclei Transmitter Gain Using 1H Signal. Tomography, 9(5), 1603-1616.
- Review of Hyperpolarized Pulmonary Functional
129Xe MR forLong‐COVID . Journal of Magnetic Resonance Imaging. - Establishing minimally important differences for cardiac MRI endpoints in pulmonary arterial hypertension. European Respiratory Journal, 2202225-2202225.
- Hyperpolarised 129-Xenon Diffusion-weighted MRI for Assessing Lung Microstructure in IPF. ERJ Open Research, 00048-2023.
- Personalising airway clearance in chronic suppurative lung diseases: a scoping review.. ERJ Open Research, 00010-2023.
- Non-invasive detection of severe PH in lung disease using magnetic resonance imaging. Frontiers in Cardiovascular Medicine, 10.
- Implementable Deep Learning for Multi‐sequence Proton
MRI Lung Segmentation: A Multi‐center, Multi‐vendor, and Multi‐disease Study. Journal of Magnetic Resonance Imaging. - Imaging gas‐exchange lung function and brain tissue uptake of hyperpolarized
129 Xe using sampling density‐weighted MRSI. Magnetic Resonance in Medicine. - Residual Lung Abnormalities Following COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID Study. American Journal of Respiratory and Critical Care Medicine.
129 Xe and Free‐Breathing1 H VentilationMRI in Patients With Cystic Fibrosis: A Dual‐Center Study. Journal of Magnetic Resonance Imaging.- Quality of reporting in AI cardiac MRI segmentation studies – A systematic review and recommendations for future studies. Frontiers in Cardiovascular Medicine, 9.
- Quantitative CT Evaluation of Small Pulmonary Vessels Has Functional and Prognostic Value in Pulmonary Hypertension. Radiology.
- 129Xe Pulmonary MRI for Individuals with Post-Acute COVID-19 Syndrome. Radiology.
- Severe pulmonary hypertension associated with lung disease is characterised by a loss of small pulmonary vessels on quantitative CT. ERJ Open Research, 00503-2021.
- Imaging and Risk Stratification in Pulmonary Arterial Hypertension: Time to Include Right Ventricular Assessment. Frontiers in Cardiovascular Medicine, 9.
- CMR Measures of Left Atrial Volume Index and Right Ventricular Function Have Prognostic Value in Chronic Thromboembolic Pulmonary Hypertension. Frontiers in Medicine, 9.
- Standalone portable xenon-129 hyperpolariser for multicentre clinical magnetic resonance imaging of the lungs. The British Journal of Radiology.
- Abnormal Gas Exchange in Nonspecific Interstitial Pneumonia at Xenon MRI. Radiology, 211524-211524.
- Lung MRI with hyperpolarised gases: current & future clinical perspectives. The British Journal of Radiology, 20210207-20210207.
- Repeatability and sensitivity to change of non-invasive end points in PAH: the RESPIRE study. Thorax.
- Finite element simulations of hyperpolarized gas DWI in micro‐CT meshes of acinar airways: validating the cylinder and stretched exponential models of lung microstructural length scales. Magnetic Resonance in Medicine.
- Imaging of Pulmonary Hypertension in Adults: A Position Paper from the Fleischner Society. Radiology, 203108-203108.
- Bayesian Inference Associates Rare KDR Variants with Specific Phenotypes in Pulmonary Arterial Hypertension. Circulation: Genomic and Precision Medicine.
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- Current state of the art MRI for the longitudinal assessment of cystic fibrosis. Journal of Magnetic Resonance Imaging.
- Free breathing lung T1 mapping using image registration in patients with idiopathic pulmonary fibrosis. Magnetic Resonance in Medicine. View this article in WRRO
- Spectral graph theory efficiently characterises ventilation heterogeneity in lung airway networks.
- Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension. European Radiology. View this article in WRRO
- Editorial : pulmonary hypertension : mechanisms and management, history and future. Frontiers in Medicine, 7. View this article in WRRO
- Magnetic resonance spectroscopy reveals mitochondrial dysfunction in amyotrophic lateral sclerosis. Brain.
- View this article in WRRO Quantification of pulmonary perfusion in idiopathic pulmonary fibrosis with first pass dynamic contrast enhanced perfusion MRI. Thorax.
- Dissolved 129Xe lung MRI with 4-echo 3D radial spectroscopic imaging: quantification of regional gas transfer in idiopathic pulmonary fibrosis. Magnetic Resonance in Medicine. View this article in WRRO
- Peripheral and proximal lung ventilation in asthma; short-term variation and response to bronchodilator. JACI.
- Measuring 129Xe transfer across the blood brain barrier using magnetic resonance spectroscopy. Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine.
- EXPRESS: Patterns of Thromboembolic Pulmonary Vascular Disease in COVID-19. Pulmonary Circulation, 204589402097919-204589402097919.
- Integrated Cardiopulmonary MRI Assessment of Pulmonary Hypertension. Journal of Magnetic Resonance Imaging.
- An asymmetrical whole‐body birdcage RF coil without RF shield for hyperpolarized 129 Xe lung MR imaging at 1.5 T. Magnetic Resonance in Medicine.
- Assessment of the Precision in Measuring Glutathione at 3 T With a MEGA‐PRESS Sequence in Primary Motor Cortex and Occipital Cortex. Journal of Magnetic Resonance Imaging.
- View this article in WRRO Xenon ventilation MRI in difficult asthma; initial experience in a clinical setting. European Respiratory Journal.
Chapters
- Hyperpolarised Helium-3 (3He) MRI: Physical Methods for Imaging Human Lung Function, MRI of the Lung (pp. 69-97). Springer International Publishing
- List of Contributors, Hyperpolarized and Inert Gas MRI (pp. xi-xii). Elsevier
- Hyperpolarized Gases in NMR, Methods and Applications, Encyclopedia of Spectroscopy and Spectrometry (pp. 163-169). Elsevier
- Dynamic Imaging of Lung Ventilation and Gas Flow With Hyperpolarized Gas MRI, Hyperpolarized and Inert Gas MRI (pp. 47-59). Elsevier
- Brain Imaging Using Hyperpolarized Xenon MRI, Hyperpolarized and Inert Gas MRI (pp. 251-262). Elsevier
- Hyperpolarized gases in NMR, methods and applications, Encyclopedia of Spectroscopy and Spectrometry (pp. 163-169).
- 129Xe chemical shift and spin-lattice relaxation dependences on blood oxygenation (pp. 365-391).
- Xe-129 Chemical Shift and Spin-Lattice Relaxation Dependences on Blood Oxygenation, HYPERPOLARIZED XENON-129 MAGNETIC RESONANCE: CONCEPTS, PRODUCTION, TECHNIQUES AND APPLICATIONS (pp. 365-391).
- Hyperpolarized Gases in NMR, Methods and Applications In Lindon J (Ed.), Encyclopedia of Spectroscopy and Spectrometry (pp. 971-978).
- Imaging of the Cardiovascular System, Thorax, and Abdomen CRC Press
- MRI methods for structural and functional assessment of the lungs: proton and multinuclear, Imaging (pp. 1-19). European Respiratory Society View this article in WRRO
- Chapter 20. 129Xe Chemical Shift and Spin–Lattice Relaxation Dependences on Blood Oxygenation, Hyperpolarized Xenon-129 Magnetic Resonance (pp. 365-391). Royal Society of Chemistry
- MRI of Pulmonary Ventilation, MRI of the Lung (pp. 35-90). Springer Berlin Heidelberg
Conference proceedings papers
- OP2 Identification of high-risk patients and treatment targets in pulmonary arterial hypertension using artificial intelligence-derived right ventricular remodelling patterns. OP2 Identification of high-risk patients and treatment targets in pulmonary arterial hypertension using artificial intelligence-derived right ventricular remodelling patterns (pp A1.2-A1)
- Regional Lung Perfusion of Computed Tomography Emphysema Subtypes on Co-registered Computed Tomography and Magnetic Resonance Imaging Scans: The MESA COPD Study. A29. WHAT IS YOUR DAMAGE? IMAGING-BASED PHENOTYPES OF COPD
- The EXPLAIN (Hyperpolarised Xenon Magnetic Resonance Pulmonary Imaging in Patients With Long-COVID) Study: The Primary Outcome. C75. STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF COVID
- Six-month Longitudinal Changes in 129-XE and HRCT Imaging Metrics Tend to Associate With On-study COPD Exacerbations. A29. WHAT IS YOUR DAMAGE? IMAGING-BASED PHENOTYPES OF COPD
- S81 Assessment of endothelial function in Long-COVID and in patients with residual lung abnormalities after COVID-19. ‘Bad blood’ – Biomarkers and mechanisms in long COVID
- S20 Long-COVID: a multi-faceted syndrome explored in the EXPLAIN study (HypErpolarised xenon magnetic resonance PuLmonary ImAging In PatieNts with Long-COVID). ‘Shake it off’ – Recovery from COVID-19
- S19 Gas exchange imaging using dissolved-phase 129Xe MRI in post COVID cohorts. ‘Shake it off’ – Recovery from COVID-19
- P177 129Xe MRI phenotyping and longitudinal change in patients with asthma and/or COPD and normal pulmonary function tests. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
- P176 Bronchodilator response discordance in patients with asthma and/or COPD assessed by 129Xe-MRI and spirometry. ‘You ain’t seen nothing yet’ – Imaging across COPD, nodules and lung cancer screening
- Age, sex and lung volume dependence of 129Xe MRI gas exchange metrics. Clinical respiratory physiology, exercise and functional imaging
- Impaired xenon gas transfer observed two years after COVID-19 hospitalisation in patients with signs of interstitial lung disease. Imaging
- Assessing personalised airway clearance techniques in Primary Ciliary Dyskinesia with 129Xe ventilation MRI. Physiotherapists
- Xe-MRI bronchodilator response to assess disease severity in patients with asthma and/or COPD. Respiratory function technologists/scientists
- Bronchodilator response discordance in patients with asthma and/or COPD using Xe-MRI and spirometry. Respiratory function technologists/scientists
- Longitudinal change in lung physiology and 129Xe MRI over 1 year in patients with asthma and/or COPD. Clinical respiratory physiology, exercise and functional imaging
- Artificial Intelligence and Computed Tomography to improve quantification and prognostication of lung disease in precapillary pulmonary hypertension. Pulmonary hypertension
- Lung physiology and 129Xe MRI data driven clustering of patients with asthma and/or COPD. Clinical respiratory physiology, exercise and functional imaging
- Unexplained lung function differences in dyspnoeic non-hospitalised Long-COVID (NHLC) patients and asymptomatic fully recovered COVID-19 controls - the EXPLAIN study. Clinical respiratory physiology, exercise and functional imaging
- Multisite implementation of 129Xe-MRI assessment of COPD disease progression: XeCITE early results. Imaging
- Lung Microstructure and Regional Function of Quantitative Emphysema Subtypes on Coregistered Computed Tomography and Hyperpolarized Gas Magnetic Resonance Imaging Scans: The M E S A - C O P D Study. D97. IMPACT OF COPD ACROSS THE LIFESPAN
- Systematic Follow-up of Patients Following Acute Pulmonary Embolism Identifies High Incidence of Chronic Thromboembolic Pulmonary Hypertension: ASPIRE CTEPH. D106. HOT OFF THE PRESSES! LATE BREAKERS IN PULMONARY VASCULAR DISEASE
- 33 Cardiac MRI thresholds for improvement in pulmonary arterial hypertension. Abstracts
- Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. 14.02 - Imaging
- Physiological assessment of patients with airways dysanapsis using 129Xe MRI. 09.01 - Respiratory function technologists/scientists
- 129Xe-MRI and lung function to phenotype ventilation heterogeneity in asthma and/or COPD. 05.02 - Monitoring airway disease
- Prognostic importance of centrilobular ground glass changes in patients with Idiopathic Pulmonary Arterial Hypertension. 13.01 - Pulmonary hypertension
- Personalising airway clearance in PCD, exploring expert physiotherapist decision making.. 09.02 - Physiotherapists
- Hyperpolarised 129Xe MR imaging of lung ventilation in neonates with bronchopulmonary dysplasia: initial experience. 14.02 - Imaging
- Comparison of 19F-MRI, CT and spirometry in a patient with airways disease. 14.02 - Imaging
- CMR assessed maladaptive right ventricular remodelling predicts treatment failure in pulmonary arterial hypertension. 13.01 - Pulmonary hypertension
- S90 Right ventricular remodelling assessed using cardiac magnetic resonance predicts survival and treatment response in pulmonary arterial hypertension. ‘The Sixth Sense’ – Prognostication in pulmonary vascular disease
- S93 Systematic follow-up of patients following acute pulmonary embolism is associated with an increased incidence of chronic thromboembolic pulmonary hypertension and less severe disease. ‘The Sixth Sense’ – Prognostication in pulmonary vascular disease
- P39 Establishing minimally important differences for cardiac MRI endpoints in pulmonary arterial hypertension. ‘Mission (Im)possible I’ – Pulmonary vascular disease
- S68 Assessing pulmonary ventilation and treatment response in patients with asthma and COPD using 19F-MRI: results from the LIFT study. ‘Back to the Future’ – Novel technology of the airways
- Training and Clinical Validation of Artificial Intelligence Derived Right Atrial Cardiovascular Magnetic Resonance Measurements. A105. YOU CAN PREDICT ALL YOU WANT, BUT EVERYONE KNOWS... (pp a2285-a2285)
- Physiological Phenotypes of Patients with Asthma and/or COPD Using 129Xe MRI. A99. LOOK AT THAT! NEW FINDINGS FROM LUNG IMAGING (pp a2175-a2175)
- Computed Tomography (CT) Features Are of Diagnostic Utility in Pre Diagnosis Idiopathic Pulmonary Arterial Hypertension (IPAH): A Case Controlled Study. B106. UNION SQUARE: OBSERVATIONAL STUDIES AND CLINICAL TRIALS IN PULMONARY HYPERTENSION (pp a3605-a3605)
- Initial Experience with Hyperpolarized Xenon-129 Gas MRI in Neonates with Bronchopulmonary Dysplasia. C51. TRACHEOSTOMIES AND BPD (pp a4356-a4356)
- A comparison of 129Xe MRI and advanced lung function testing in patients with asthma and /or COPD: The NOVELTY ADPro substudy. Imaging
- A fully automated cardiac magnetic resonance (CMR) assessment improves the evaluation of patients with pulmonary arterial hypertension (PAH). Imaging
- MRI metric lung parenchyma T1 indicates lung pathology in patients with pulmonary hypertension. Pulmonary hypertension
- Estimation of the Alveolar Partial Pressure of Oxygen using Hyperpolarized Helium-3: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study. Imaging
- 19 Cardiac magnetic resonance to identify raised left ventricular filling pressure. Abstracts
- S75 Hyperpolarised 129-xenon MRI in differentiating between fibrotic and inflammatory interstitial lung disease and assessing longitudinal change. Basic science in ILD: what drives progression?
- Hyperpolarized Gas MRI Ventilation Synthesis From CT: Comparison of Conventional and Deep Learning Methods. MEDICAL PHYSICS, Vol. 48(6)
- Comparison of 3D Deep Convolutional Neural Networks and Training Strategies for Ventilated Lung Segmentation Using Multi-Nuclear Hyperpolarized Gas MRI. MEDICAL PHYSICS, Vol. 48(6)
- Deep Learning-Based Survival Prediction for Non-Small Cell Lung Cancer Patients Undergoing Radical Radiotherapy. JOURNAL OF THORACIC ONCOLOGY, Vol. 16(10) (pp S902-S903)
- 3D deep convolutional neural network-based ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI. Thoracic Image Analysis, Vol. 12502 (pp 24-35). Lima, Peru, 8 October 2020 - 8 October 2020. View this article in WRRO
- Lung perfusion in pulmonary hypertension – results from the RESPIRE study. Pulmonary hypertension
- Ventilation defect quantification on 3He MRI through deep learning: the MESA COPD Study. Imaging
- Assessing bronchodilator response in patients with asthma and COPD using 19F-MRI. Imaging
- Reproducibility of 3He-MRI acquisition assessed by a deep learning approach: ventilation defects in the VaPE-Tox pilot study. Imaging
- Benchmarking inhaled nanoparticle measurements of airspace dimension with hyperpolarised 129Xe diffusion-weighted MRI. Imaging
- Regional hyperpolarised 129-xenon diffusion-weighted MRI in patients with IPF. Imaging
- Oxygen enhanced MRI biomarkers of lung function in interstitial lung disease. Imaging
- Cardiac MRI right atrial area measurement thresholds for risk stratification in patients with PAH. Pulmonary hypertension
- Percent-predicted incremental shuttle walking test distance stratifies risk in pulmonary arterial hypertension. Pulmonary hypertension
- Sex bias exists in diagnosing pulmonary arterial hypertension via machine learning. Pulmonary hypertension
- Cardiac MRI for Prognosis in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis. Imaging
- Serial cardiac MRI for assessment of cardiac morphology and function in CTEPH patients after PEA or vasodilator therapy. Pulmonary hypertension
- Interpretation of multiple breath washout (MBW) measurements of lung function using mathematical modelling and hyperpolarised 3He gas MRI. Respiratory infections
- MR LV Systolic Eccentricity Index (SEI) Compared To Established Cardiac Mr Parameters For The Diagnosis Of PH: Correlation With Right Heart Catheterization. D26. PULMONARY VASCULAR AND RIGHT HEART PHYSIOLOGY
- NOVEL METHODS IN THE ASSESSMENT OF AORTIC STENOSIS. Journal of the American College of Cardiology, Vol. 75(11) (pp 1684-1684)
- ALTERED LEFT VENTRICULAR BLOOD FLOW PATTERN AND KINETIC ENERGY IN PATIENTS UNDERGOING AORTIC VALVE INTERVENTION. Journal of the American College of Cardiology, Vol. 75(11) (pp 1763-1763)
- S125 Quantitative CT and hyperpolarised 129-xenon diffusion-weighted MRI in interstitial lung disease. ‘Under your skin’ – imaging in lung disease
- S124 Multi-centre reproducibility of 19F-MR ventilation imaging in healthy volunteers. ‘Under your skin’ – imaging in lung disease
- Compressed sensing to reduce breath-hold duration in 19F-MR ventilation imaging. Imaging
- HELIUM MRI. PEDIATRIC PULMONOLOGY, Vol. 54 (pp S70-S71)
- 1H and 129Xe MRI to detect functional and structural lung disease in sub-clinical cystic fibrosis. Cystic fibrosis
- Clinical applicability of 3He and 129Xe ventilation MRI in cystic fibrosis: longitudinal follow up. Cystic fibrosis
- A prospective study comparing the repeatability and sensitivity to change of non-invasive endpoints in pulmonary arterial hypertension: the RESPIRE study. Pulmonary hypertension
- Repeatability and Sensitivity to change of right ventricular analysis methods using cardiac magnetic resonance imaging in PAH: results from the RESPIRE Study. Imaging
- Imaging functional and microstructural changes in the lungs of children born prematurely. Imaging
- Hyperpolarised 129-xenon diffusion-weighted MRI in interstitial lung disease. Imaging
- Correlations of ventilation heterogeneity and spirometry in asthma; initial experience with hyperpolarised gas MRI in a clinical setting. Imaging
- Longitudinal change in hyperpolarised 129-xenon MR spectroscopy in interstitial lung disease. Imaging
- Diagnostic and prognostic value of a diagnostic CT regression model in suspected pulmonary hypertension. Pulmonary hypertension
- Diagnostic accuracy of right ventricular trabecular mass measurements as measured on cardiac MRI in suspected pulmonary hypertension. Pulmonary hypertension
- Validation of nitric oxide transfer factor predicted equations. Respiratory function technologists/scient.
- Free breathing lung MRI T1 in patients with idiopathic pulmonary fibrosis and healthy volunteers. Imaging
- Predicting multiple breath washout outcomes from hyperpolarised gas magnetic resonance imaging (MRI). Imaging
- P212 Ventilation MRI tracks longitudinal lung function changes in patients with cystic fibrosis and clinically stable FEV1 and Lung Clearance Index. Journal of Cystic Fibrosis, Vol. 18 (pp S117-S117)
- WS17-2 The sensitivity of MRI to detect both functional and structural lung abnormalities in sub-clinical cystic fibrosis. Journal of Cystic Fibrosis, Vol. 18 (pp S32-S32)
- P213 A comparison of ventilation MRI using hyperpolarised 3He and 129Xe to assess cystic fibrosis lung disease. Journal of Cystic Fibrosis, Vol. 18 (pp S117-S117)
- P211 129Xe ventilation MRI and LCI to assess acute maximal exercise as a method of airway clearance. Journal of Cystic Fibrosis, Vol. 18 (pp S116-S117)
- 284An accurate, multi-parametric cardiovascular magnetic resonance model to predict mean pulmonary artery pressure in pulmonary hypertension. European Heart Journal - Cardiovascular Imaging, Vol. 20(Supplement_2)
- P165A novel cardiac magnetic resonance imaging model to predict level of mixed venous oxygen levels in pulmonary hypertension. European Heart Journal - Cardiovascular Imaging, Vol. 20(Supplement_2) View this article in WRRO
- P612Averaged, diastolic mitral inflow velocity mapping versus peak velocity for the assessment of left ventricular haemodynamics. European Heart Journal - Cardiovascular Imaging, Vol. 20(Supplement_2) View this article in WRRO
- OC-0523 3He MRI for functional lung avoidance VMAT treatment planning in lung cancer. Radiotherapy and Oncology, Vol. 133 (pp S274-S275) View this article in WRRO
- A Metasurface for Multi-Nuclear Magnetic Resonance Imaging Applications at 1.5T. 13th European Conference on Antennas and Propagation, EuCAP 2019
- Cardiac MRI: Identifying Thresholds to Predict Mortality in Pulmonary Arterial Hypertension. B27. HEARTBREAKER: HEART FAILURE AND PULMONARY HYPERTENSION
- Late Breaking Abstract - Apparent diffusion coefficient by 3He MRI and quantitative emphysema subtypes by CT. EUROPEAN RESPIRATORY JOURNAL, Vol. 54
- Averaged, diastolic mitral inflow velocity mapping versus peak velocity for the assessment of left ventricular haemodynamics. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol. 20 (pp 494-495)
- A novel cardiac magnetic resonance imaging model to predict level of mixed venous oxygen levels in pulmonary hypertension. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol. 20 (pp 121-121)
- S90 Assessing regional lung ventilation in patients and healthy volunteers using 19F-MRI of inhaled perfluoropropane. It’s all about your image: new approaches to thoracic imaging
- P16 Identifying partial anomalous pulmonary venous drainage (PAPVD) in patients presenting with suspected pulmonary hypertension (PH). Under pressure: an update in pulmonary vascular disease
- Probing diffusion and perfusion in idiopathic pulmonary fibrosis with hyperpolarised xenon and dynamic contrast-enhanced magnetic resonance imaging. Thorax, Vol. 73(Suppl 4) (pp A44-A45). London, UK, 5 December 2018 - 7 December 2018. View this article in WRRO
- A Single Unit Cell Metasurface for Magnetic Resonance Imaging Applications. 2018 12th International Congress on Artificial Materials for Novel Wave Phenomena (Metamaterials), 27 August 2018 - 1 September 2018.
- Investigating Exercise Induced Laryngeal Obstruction (EILO): A review of a specialist paediatric service. Respiratory function technologists/scient
- The effect of inhaled lung volume on ventilation heterogeneity in CF using 3He MRI. Cystic fibrosis
- Indacaterol/glycopyrronium increases lung ventilation in COPD patients as measured by hyperpolarized 3He MRI. Airway pharmacology and treatment
- Drug induced interstitial lung disease : a systematic review. European Respiratory Journal, Vol. 52(Suppl 62). Paris, France, 15 September 2018 - 19 September 2018. View this article in WRRO
- Comparison of 1H MRI and 3He MRI ventilation images in patients with cystic fibrosis and patients with lung cancer. Imaging
- Assessing regional lung ventilation with 19F-MRI of inhaled perfluoropropane. Imaging
- Anomalous pulmonary venous drainage (APVD) in patients with suspected pulmonary hypertension (PH). Pulmonary hypertension
- Comparison of inhaled 19F C3F8 and hyperpolarized 129Xe lung ventilation MRI. Imaging
- OC-0182: A comparison of CT ventilation with 3He and 129Xe MRI for functional avoidance treatment planning. Radiotherapy and Oncology, Vol. 127(Supplement 1) (pp S96-S97). Barcelona, Spain, 20 April 2018 - 24 April 2018. View this article in WRRO
- Low and Absent Ventilation Percent on He-3 MRI and Cardiac Function: The Mesa COPD Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Endothelial and Platelet Activation in the Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Dynamic Contrast-Enhanced Magnetic Resonance Imaging for the Evaluation of Perfusion Heterogeneity in Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Prognostic Value of T1 Mapping in Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Diastolic Septal Angle Is an Independent Predictor of Right Ventricular Insertion Point T1 in Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Hyperpolarised Gas MRI Shows Reversibility of Lung Ventilation Defects at Increased Inspiratory Lung Volumes in Cystic Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Diagnostic Accuracy and Reproducibility of Unenhanced Computed Tomography in Suspected Pulmonary Hypertension: Pulmonary Arterial and Cardiac Metrics. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Cardiac MRI Measured Left Atrial Function Can Identify Patient with Pulmonary Hypertension Due to Left Heart Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Assessment of Suitable Patients and Targets for Lung Volume Reduction with Endobronchial Valves in COPD. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 197
- Septal angle on MRI predicts combined pre and post capillary pulmonary hypertension. Thorax, Vol. 72(Suppl 3) (pp A31-A32), 6 December 2017 - 8 December 2017. View this article in WRRO
- P177 Computed tomography diagnostic model for diagnosis of pulmonary hypertension. Pulmonary vascular disease: monitoring and managing
- P183 Impact of patient choice on survival in patients with chronic thromboembolic pulmonary hypertension offered pulmonary endarterectomy. Pulmonary vascular disease: monitoring and managing
- S52 Computed tomography in the diagnosis of left heart disease in patients with suspected pulmonary hypertension. Diagnosing and treating pulmonary vascular disease
- Longitudinal monitoring of lung microstructure with HP gas diffusion-weighted MRI in mild cystic fibrosis children. Cystic Fibrosis View this article in WRRO
- Hyperpolarised gas ventilation MRI detects early lung ventilation heterogeneity in children with primary ciliary dyskinesia. Paediatric Respiratory Physiology and Sleep
- Late breaking abstract - Hyperpolarised gas MRI demonstrates sub-clinical progression in IPF over 6 months. European Respiratory Journal, Vol. 50(Suppl 61). Milan, Italy, 9 September 2017 - 13 September 2017. View this article in WRRO
- Ventilation heterogeneity assessed in patients with mild cystic fibrosis and asthma using Hyperpolarised gas MRI histogram analysis. Imaging
- New Disagreement Metrics Incorporating Spatial Detail – Applications to Lung Imaging (pp 804-814) View this article in WRRO
- A Reconfigurable Capacitive Impedance Surface for 1.5T Magnetic Resonance Imaging Applications. Loughborough Antennas & Propagation Conference (LAPC 2017)
- P2.05-032 CT-Based Surrogates of Pulmonary Ventilation in Lung Cancer: A Voxel-Level Comparison with HP Gas MRI. Journal of Thoracic Oncology, Vol. 12(1) (pp S1050-S1050)
- Three Element Windkessel Model to Non-Invasively Assess PAH Patients: One Year Follow-up (pp 151-154)
- A reflective capacitive impedance surface for 1.5 Tesla magnetic resonance imaging applications. 2016 Loughborough Antennas & Propagation Conference (LAPC), 14 November 2016 - 15 November 2016.
- S111 Differences in characteristics and outcomes in systemic sclerosis-associated and idiopathic pulmonary arterial hypertension. Thorax, Vol. 71(Suppl 3) (pp A66-A67)
- Non-invasive methods for the estimation of MPAP in COPD patients using cardiac MRI. Thorax, Vol. 71(Suppl 3) (pp A106-A107), 7 December 2016 - 9 December 2016. View this article in WRRO
- P28 Chronic thromboembolic pulmonary hypertension: long term outcomes in surgical and non-surgical patients. Thorax, Vol. 71(Suppl 3) (pp A98.1-A98)
- LONGITUDINAL MONITORING OF DISEASE PROGRESSION IN CHILDREN WITH MILD CF USING 3-HELIUM MRI AND LCI. Pediatric Pulmonology, Vol. 51 (pp 348-348) View this article in WRRO
- Regional phase III slope measurement using hyperpolarized gas MR imaging. 1.3 Imaging View this article in WRRO
- Response to treatment assessment in patients with PAH by MRI based computational modelling. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Idiopathic and systemic sclerosis-associated PAH: A comprehensive haemodynamic and radiological comparison. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- MRI derived left atrial volume index predicts treatment response in patients with PAH. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- Diffusion-weighted hyperpolarised gas MRI in idiopathic pulmonary fibrosis : reproducibility and clinical significance. ERS International Congress 2016 abstracts, Vol. 48(Suppl 60). London, UK, 3 September 2016 - 7 September 2016. View this article in WRRO
- Longitudinal monitoring of disease progression in children with mild CF using hyperpolarised gas MRI and LCI. 9.1 Respiratory Function Technologists/Scientists View this article in WRRO
- Ventilation CT : voxel-level comparison with HP gas MRI. European Respiratory Journal, Vol. 48(Suppl 60). Estoril, Portugal, 10 March 2016 - 13 March 2016. View this article in WRRO
- Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5 T. European Respiratory Journal, Vol. 48(suppl 60), 3 September 2016 - 7 September 2016. View this article in WRRO
- Change in right atrial minimal volume is a prognostic marker in pulmonary arterial hypertension (PAH). 1.3 Imaging
- Comparison of phase III slope analysis from MBW with hyperpolarised gas MRI in children with mild CF. 9.1 Respiratory Function Technologists/Scientists
- Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- Idiopathic and systemic sclerosis-associated PAH: A comprehensive haemodynamic and radiological comparison. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- Chronic thrombo-embolic pulmonary hypertension: Long-term outcomes in operated and non-operated patients. 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases
- WE-AB-202-07: Ventilation CT: Voxel-Level Comparison with Hyperpolarized Helium-3 & Xenon-129 MRI. Medical Physics, Vol. 43(6) (pp 3795-3796), 31 July 2016 - 4 August 2016. View this article in WRRO
- WS15.2 Multiple breath washout and imaging with 3 He MRI and CT scans to monitor early-stage lung disease in patients with cystic fibrosis. Journal of Cystic Fibrosis, Vol. 15 (pp S24-S25)
- Evaluation of High Impedance Surfaces for MRI RF coil applications - simulations of RF field and Specific Absorption Rate. 2016 10th European Conference on Antennas and Propagation (EuCAP), 10 April 2016 - 15 April 2016. View this article in WRRO
- Response to treatment assessment in patients with PAH by MRI based computational modelling. EUROPEAN RESPIRATORY JOURNAL, Vol. 48
- A high impedance surface for improving the radio frequency magnetic field for a 1.5 Tesla Magnetic Resonance system. 2015 Loughborough Antennas & Propagation Conference (LAPC), 2 November 2015 - 3 November 2015.
- P286 Correlations of functional multi-nuclear MR imaging indices with pulmonary function tests in the assessment of idiopathic pulmonary fibrosis. Thorax, Vol. 70(Suppl 3) (pp A223.1-A223)
- P285 Helium Magnetic Resonance Imaging Identifies Regional Ventilation, Perfusion and Microstructure Abnormalities in a Case of “Horse-shoe” Lung. Thorax, Vol. 70(Suppl 3) (pp A222-A223)
- P283 Hyperpolarised Gas MRI – a pathway to Clinical Diagnostic Imaging. Thorax, Vol. 70(Suppl 3) (pp A220.3-A221)
- Tricuspid deceleration time predicts right atrial pressure in patients with suspected pulmonary hypertension: Preliminary experience with cardiac magnetic resonance imaging. 1.3 Imaging
- Paediatric paradoxical vocal cord dysfunction: Diagnosis and treatment in a multidisciplinary clinic. 9.2 Physiotherapists
- Prognostic value of MRI in pulmonary arterial hypertension: Early and late predictors. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Lobar comparison of CT densitometry and3He diffusion MRI models of lung microstructure in asthmatics. 1.3 Imaging
- Multi nuclear 3D multiple breath washout imaging with hyperpolarised3He and129Xe MRI. 1.3 Imaging
- Repeatability of129Xe MR methods for quantification of interstitial thickness. 4.1 Clinical respiratory physiology, exercise and functional imaging
- Hyperpolarised gas MR lung imaging – Breaks through to clinical practice. 1.3 Imaging
- Effect of posture on lung clearance index (LCI) and lung volumes in children with early stage cystic fibrosis lung disease. 9.1 Respiratory Function Technologists/Scientists
- Assessment of lung microstructure in ILD with3He and129Xe MRI. 4.1 Clinical respiratory physiology, exercise and functional imaging
- Comparison of ventilation heterogeneity (VH) measured with multiple breath washout (MBW) imaging to whole lung MBW LCI and FEV1in asthma and cystic fibrosis (CF). 4.1 Clinical respiratory physiology, exercise and functional imaging
- Estimation of mPAP with MRI in pulmonary hypertension subgroups: Comparison with echocardiography. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Improved diagnostic accuracy of MRI in patients with suspected pulmonary hypertension with combined right ventricle and pulmonary artery metrics. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Diagnosis of pulmonary hypertension from MR image based computational models of pulmonary vascular haemodynamics and decision tree analysis. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Myocardial T1 mapping MRI in patients with PH and age-matched healthy volunteers. 4.3 Pulmonary Circulation and Pulmonary Vascular Disease
- Cardiac Hemodynamics In COPD And Emphysema Estimated By Magnetic Resonance Imaging. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 191
- Joint Clustering and Component Analysis of Correspondenceless Point Sets: Application to Cardiac Statistical Modeling (pp 98-109)
- Reusability of Statistical Shape Models for the Segmentation of Severely Abnormal Hearts (pp 257-264)
- S120 Right Ventricular Dysfunction In Pulmonary Hypertension With Combined Pulmonary Fibrosis And Emphysema Syndrome. Thorax, Vol. 69(Suppl 2) (pp A64-A65)
- P273 Assessment Of Lung Microstructure In Interstitial Lung Disease With Hyperpolarised Gas Mri. Thorax, Vol. 69(Suppl 2) (pp A192-A193)
- Quantitative lung T-1 mapping and oxygen enhanced MRI in IPF. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- Delayed gas filling imaged in asthma patients using hyperpolarised He-3 MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- Visualising regional ventilation heterogeneity by linking multiple breath washout to He-3 MRI imaging. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- Feasibility of high quality lung MRI with naturally abundant hyperpolarised Xe-129. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- Age-dependent changes in whole-lung septal thickness measured by Xe-129 MRI: A comparison of healthy volunteers and subjects with IPF. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- Age-dependent changes in whole-lung septal thickness measured by Xe-129 MRI: A comparison of healthy volunteers and subjects with IPF. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- Detection of early-stage lung disease in cystic fibrosis; comparing the sensitivity of He-3 and H-1 MRI, CT and LCI. EUROPEAN RESPIRATORY JOURNAL, Vol. 44
- WS13.5 Visualising ventilation heterogeneity in mild CF using hyperpolarised 3He MRI, and comparison with lung clearance index (LCI). Journal of Cystic Fibrosis, Vol. 13 (pp S28-S28)
- Mutli-Nuclear Mr Imaging Of Vq Distribution Response To Bronchodilator In Asthma. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
- Quantitative Mapping Of Treatment Response In The Lungs Of Asthmatics Using Hyperpolarized Ventilation Helium-3 Mri. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
- Dissolved 129xe Mri - Delayed Gas Uptake Indicates Septal Thickening In Patients With Idiopathic Pulmonary Fibrosis And Systemic Sclerosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
- Reproducibility Of Lung Ventilation Volume From Helium-3 And Proton Mri In Asthmatics. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
- Linking Helium-3 Mri Washout Imaging To Multiple Breath Washout - First Steps To Understanding Regional Lung Ventilation Heterogeneity. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
- Assessment Of Structural And Functional Changes In Early Stage Cf With Helium-3 Mri, CT And Multi-Breath Washout. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
- Mapping The Microscopic Distribution Of Acinar Airway Length Scales Using Fractal Exponential Analysis Of Helium-3 Diffusion Mri. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 189
- Automatic, Simultaneous, Non-invasive Measurements of Flow and Area in the Human Pulmonary Arteries from MRI Images (pp 259-264)
- P157 Hepatocyte growth factor concentration correlates with haemodynamic severity in connective tissue disease-associated pulmonary arterial hypertension. Thorax, Vol. 68(Suppl 3) (pp A146.2-A147)
- HYPERPOLARISED 3HE MRI IS SUPERIOR TO LUNG CLEARANCE INDEX IN DETECTION OF VENTILATION ABNORMALITIES IN YOUNG CHILDREN WITH MILD CF. THORAX, Vol. 68 (pp A7-A8)
- (HE)-H-3 MRI IN YOUNG ADULTS WITH CONGENITAL DIAPHRAGMATIC HERNIA: ALVEOLAR SIZE DIFFERENCES BETWEEN THE IPSI- AND CONTRALATERAL LUNG. INTENSIVE CARE MEDICINE, Vol. 39 (pp S107-S107)
- Imaging The Effect Of Airway Opening In Asthma Due To Inflation State With 3he Mri. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol. 187
- Measuring red blood cell oxygenation in vivo using hyperpolarized 129Xe MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- He-3 MRI in young adults with congenital diaphragmatic hernia: Alveolar size differences between lungs. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Quantifying lung function in COPD with hyperpolarised He-3 MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Simultaneous imaging of lung structure and function with triple nuclear MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Modelling of hyperpolarized gas diffusion in lungs of COPD patients and healthy volunteers using a fractional dynamics approach. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Non-invasive estimation of pulmonary artery pressure and resistance with CMR imaging: Derivation and prospective validation cohort study. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- MRI of delayed-ventilation perfusion matching in COPD. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- MRI assessment of right atrial volume and function in pulmonary hypertension. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Simultaneous imaging of lung structure and function with triple nuclear MRI. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Prognostic value of ventricular volumes and function in patients with pulmonary hypertension due to chronic obstructive pulmonary disease. EUROPEAN RESPIRATORY JOURNAL, Vol. 40
- Direct Imaging Of Delayed And Collateral Ventilation In COPD Using Hyperpolarised Gas MRI. D100. THE BIG ROLE OF SMALL AIRWAYS
- Evaluation Of MR Lung Perfusion In The Assessment Of Chronic Thromboembolic Pulmonary Hypertension. C28. DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION
- Imaging V/Q In Chronic Thromboembolic Pulmonary Hypertension With 3He And 1H MRI. B98. NOVEL APPROACHES TO LUNG IMAGING
- Characteristics And Outcomes In Pulmonary Hypertension Associated With COPD/ Emphysema: Results From The ASPIRE Registry. B107. BIOMARKERS AND PREDICTORS OF OUTCOMES IN PULMONARY HYPERTENSION
- S20 Time-resolved CT pulmonary angiography contrast transit time in patients with pulmonary embolism: a novel functional CT metric of right heart strain?. Thorax, Vol. 66(Suppl 4) (pp A12-A12)
- 1290 poster IMAGE REGISTRATION OF LUNG CT AND HYPERPOLARIZED HELIUM-3 MRI VIA PROTON MRI FOR PATIENTS WITH NSCLC. Radiotherapy and Oncology, Vol. 99 (pp S481-S482)
- USING HYPERPOLARISED HELlUM-3 MRI TO DETECT CHANGES IN VENTILATION AFTER RADICAL LUNG RADIOTHERAPY. RADIOTHERAPY AND ONCOLOGY, Vol. 88 (pp S292-S292)
- IMAGE REGISTRATION OF HYPERPOLARIZED 3HE MRI AND X-RAY CT IMAGES OF THE LUNG VIA 1H MRI AND MUTUAL INFORMATION. RADIOTHERAPY AND ONCOLOGY, Vol. 88 (pp S372-S372)
- Implementation of dissolved 129Xe lung MRI with 4-echo 3D radial spectroscopic imaging at 3T: comparing with results at 1.5T in healthy volunteers. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
- Differentiating patients with asthma and/or chronic obstructive pulmonary disease using lung T1 and M0. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
- Investigating Rb vapor density and temperature distributions in a high throughput 129Xe-Rb polarizer. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
- Longitudinal 129Xe MRI assessment of lung gas transfer and microstructure over 1 year in patients with asthma and/or COPD. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
- Batch-mode production of hyperpolarised xenon gas with a continuous-flow polariser for preclinical and clinical human lung ventilation images. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
- Improving Xenon-129 Lung Ventilation Image Quality with a Commercial Deep-Learning Based Image Reconstruction. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
- Modelling Whole-Lung and Regional Carbon Monoxide Transfer Factor with Hyperpolarized 129Xe MRI in Asthma and COPD Patients. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
- 129Xe gas transfer lung MRI before and after bronchodilator inhalation in patients with asthma and/or COPD. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
- Impaired xenon gas transfer observed one year after hospitalisation due to COVID-19 in patients with signs of interstitial lung disease.. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
- Age and lung volume dependence of dissolved xenon-129 imaging parameters. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- Longitudinal comparison of quantitative UTE lung MRI and CT biomarkers in interstitial lung disease. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- Hyperpolarized 129Xe MR Imaging in Neonates with Bronchopulmonary Dysplasia: Feasibility and Challenges. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- 129Xe chemical shift mapping in the lungs with 3D density-weighted MRSI. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- Dissolved 129Xe spectroscopy in the lungs of preterm-born children. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- 129Xe MRI patterns of lung function in patients with asthma and/or COPD in the NOVELTY study. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- Multinuclear lung MRI assessment of COVID-19 patients at 6 and 12 weeks after hospital admission. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- Multi-modal assessment of dose-related changes in regional lung function in non-small cell lung cancer patients receiving radiotherapy. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- Deep learning-based synthesis of hyperpolarized gas MRI ventilation from 3D multi-inflation proton MRI. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
- A multi-channel deep learning approach for lung cavity estimation from hyperpolarized gas and proton MRI. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.
Other
- MRI Prediction of Precapillary Pulmonary Hypertension according to the Sixth World Symposium on Pulmonary Hypertension. Radiology, 294(2), 482-482. View this article in WRRO
- Reply to Hou et al.: Can Magnetic Resonance Imaging Effectively Evaluate the Prognosis of Patients with Pulmonary Arterial Hypertension?. American Journal of Respiratory and Critical Care Medicine, 197(5), 676-677.
- Commentaries on Viewpoint: Could lobar flow sequencing account for convection-dependent ventilation heterogeneity in normal humans?. Journal of Applied Physiology, 121(2), 592-592. View this article in WRRO
- Response to: ‘CT assessment for pulmonary hypertension requires systematic assessment of cardiac, vascular and parenchymal signs’ by Marloeset al. Thorax, 70(11), 1087.2-1088.
- Reply to Verbanck and Paiva.. J Appl Physiol (1985), 116(9), 1258.
- On the use of 3He diffusion magnetic resonance as evidence of neo-alveolarization during childhood and adolescence.. Am J Respir Crit Care Med, 189(4), 501-502.
- Response to Commentary on "The influence of lung airways branching structure and diffusion time on measurements and models of short-range 3He gas MR diffusion".. J Magn Reson, 239, 143-146.
- 3D contrast-enhanced lung perfusion MRI is an effective screening tool for chronic thromboembolic pulmonary hypertension: results from the ASPIRE Registry.. Thorax, 68(7), 677-678.
- Authors' response to assessment of intraparenchymal lung collateral ventilation. Thorax.
Preprints
- Interstitial lung damage following COVID-19 hospitalisation: an interim analysis of the UKILD Post-COVID study, Cold Spring Harbor Laboratory.
- The Investigation of Pulmonary Abnormalities using Hyperpolarised Xenon Magnetic Resonance Imaging in Patients with Long-COVID, Cold Spring Harbor Laboratory.
- Model-based Bayesian inference of the ventilation distribution in patients with Cystic Fibrosis from multiple breath washout, with comparison to ventilation MRI, Cold Spring Harbor Laboratory.
- Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension, Cold Spring Harbor Laboratory.
- Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI, Cold Spring Harbor Laboratory.
- Research group
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I currently supervise 5 PhD students
Graduated PhD students: Anderson Mon (2004), Kevin Teh (2006), Hoonsin Cheong (2008), Neil Woodhouse (2007), Martin Deppe (2010), Salma Ajraoui (2010), Andrew Swift (2012), Smitha Rajaram (2013), Xiaoxun Xu (2015), Felix Horn (2015), Graham Norquay (2015) , Madhwesha Rao (2016), Angela Lungu (2016), Neil Stewart (2016), Bilal Tahir (2016), Paul Hughes (2017), Ho Fung Chan (2018), Chris Johns (2018), Nick Weatherley (2018).
I am involved in international teaching in MR physics and pulmonary imaging:
- Grants
- Professional activities and memberships
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- Deputy Editor Journal of Magnetic Resonance Imaging.
- Member of the Fleischner Society.
- Director of Research Insigneo.
- NIHR Research Professor 2013-2018.
- EPSRC Advanced Research Fellow 2006-2011.
- EPSRC peer review college member.
- Medical Futures Award for Translational Respiratory Innovation 2011.
- Chairman (2008-2011) and Secretary (2005-2008) of the BRSG the Magnetic Resonance Group of the Institute of Physics.
- 2008-2009 Chairman ISMRM study group of hyperpolarised MRI.
- 2011-2014 Chair of the European Society of Thoracic Imaging Research Committee.
- Member of European Respiratory Society Imaging workgroup.
- MHRA QP licence holder for manufacture of hyperpolarised contrast agents (3He and 129Xe).
- Honorary Chair in MR Physics at the University of Oxford.