Dr Henry H. Roehl

All publications

Journal articles

• Greaves S, Marsay KS, Monk PN, Roehl H & Partridge LJ (2022) Tetraspanin Cd9b plays a role in fertility in zebrafish. PLOS ONE, 17(11). View this article in WRRO
• Marsay KS, Greaves S, Mahabaleshwar H, Ho CM, Roehl H, Monk PN, Carney TJ & Partridge LJ (2021) Tetraspanin Cd9b and Cxcl12a/Cxcr4b have a synergistic effect on the control of collective cell migration. PLoS ONE, 16(11). View this article in WRRO
• Garcia Romero MM, McCathie G, Jankun P & Roehl HH (2018) Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells. Nature Communications, 9(1), ---. View this article in WRRO
• Roehl HH (2018) Linking wound response and inflammation to regeneration in the zebrafish larval fin.. The International Journal of Developmental Biology, 62(6-8), 473-477. View this article in WRRO
• Felber K, Elks PM, Lecca M & Roehl HH (2015) Expression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast Differentiation. PLOS ONE, 10(12). View this article in WRRO
• Dyer C, Blanc E, Hanisch A, Roehl H, Otto GW, Yu T, Basson MA & Knight R (2014) A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain.. Development, 141(1), 63-72.
• Gray C, Bratt D, Lees J, daCosta M, Plant K, Watson OJ, Solaymani-Kohal S, Tazzyman S, Serbanovic-Canic J, Crossman DC , Keavney BD et al (2013) Loss of function of parathyroid hormone receptor 1 induces Notch-dependent aortic defects during zebrafish vascular development.. Arterioscler Thromb Vasc Biol, 33(6), 1257-1263.
• Luo L, Shamsudin S, Twyman L, Cecchin D, Battaglia G, Hua P, Roehl H & Chen B (2012) Delivery systems for small molecule antiprion drug candidates. PRION, 6, 99-99. View this article in WRRO
• Wiweger MI, Zhao Z, van Merkesteyn RJP, Roehl HH & Hogendoorn PCW (2012) HSPG-deficient zebrafish uncovers dental aspect of multiple osteochondromas. PLoS ONE, 7(1). View this article in WRRO
• Sousa S, Afonso N, Bensimon-Brito A, Fonseca M, Simões M, Leon J, Roehl H, Cancela ML & Jacinto A (2011) Differentiated skeletal cells contribute to blastema formation during zebrafish fin regeneration. Development, 138(18), 3897-3905.
• Trikic MZ, Monk P, Roehl H & Partridge LJ (2011) Regulation of Zebrafish Hatching by Tetraspanin cd63, 6. View this article in WRRO
• Knight RD, Mebus K, d'Angelo A, Yokoya K, Heanue T & Roehl H (2011) Ret signalling integrates a craniofacial muscle module during development. Development, 138(10), 2015-2024.
• Thompson MJ, Louth JC, Ferrara S, Jackson MP, Sorrell FJ, Cochrane EJ, Gever J, Baxendale S, Silber BM, Roehl HH & Chen B (2011) Discovery of 6-substituted indole-3-glyoxylamides as lead antiprion agents with enhanced cell line activity, improved microsomal stability and low toxicity.. Eur J Med Chem, 46(9), 4125-4132.
• Felber K, Croucher P & Roehl HH (2011) Hedgehog signalling is required for perichondral osteoblast differentiation in zebrafish.. Mech Dev, 128(1-2), 141-152.
• Roehl HH & Pacifici M (2010) Shop talk: Sugars, bones, and a disease called multiple hereditary exostoses.. Dev Dyn, 239(6), 1901-1904.
• Li N, Kelsh RN, Croucher P & Roehl HH (2010) Regulation of neural crest cell fate by the retinoic acid and Pparg signalling pathways.. Development, 137(3), 389-394.
• Knight R, Mebus K & Roehl H (2009) Ret tyrosine kinase signalling is required for the development of a functionally related set of zebrafish head muscles. MECHANISMS OF DEVELOPMENT, 126, S161-S161.
• Li N, Felber K, Elks P, Croucher P & Roehl HH (2009) Tracking gene expression during zebrafish osteoblast differentiation. Developmental Dynamics, 238(3), spcone-spcone.
• Wiweger M, Roehl H & Hogendoorn PCW (2009) Zebrafish Model for Studies on Bone Defects in Multiple Osteochondromas. MODERN PATHOLOGY, 22, 25A-25A.
• Wiweger M, Roehl H & Hogendoorn PCW (2009) Zebrafish Model for Studies on Bone Defects in Multiple Osteochondromas. LABORATORY INVESTIGATION, 89, 25A-25A.
• Li N, Felber K, Elks P, Croucher P & Roehl HH (2009) Tracking gene expression during zebrafish osteoblast differentiation.. Dev Dyn, 238(2), 459-466.
• Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA , Zhou Y et al (2008) montalcino, A zebrafish model for variegate porphyria. Experimental Hematology, 36(9), 1132-1142.
• Laue K, Daujat S, Crump JG, Plaster N, Roehl HH, Kimmel CB, Schneider R, Hammerschmidt M & Tuebingen 2000 Screen Consortium (2008) The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. DEVELOPMENT, 135(11), 1935-1946.
• Clément A, Wiweger M, von der Hardt S, Rusch MA, Selleck SB, Chien C-B & Roehl HH (2008) Regulation of zebrafish skeletogenesis by ext2/dackel and papst1/pinscher.. PLoS Genet, 4(7), e1000136. View this article in WRRO
• Schorpp M, Bialecki M, Diekhoff D, Walderich B, Odenthal J, Maischein HM, Zapata AG, Boehm T, van Bebber F, Busch-Nentwich E , Dahm R et al (2006) Conserved functions of Ikaros in vertebrate lymphocyte development: Genetic evidence for distinct larval and adult phases of T cell development and two lineages of B cells in zebrafish. Journal of Immunology, 177(4), 2463-2476.
• Wingert RA, Galloway JL, Barut B, Foott H, Fraenkel P, Axe JL, Weber GJ, Dooley K, Davidson AJ, Schmidt B , Paw BH et al (2005) Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature, 436(7053), 1035-1039.
• Jülich D, Chiaw HL, Round J, Nicolaije C, Schroeder J, Davies A, Van Bebber F, Busch-Nentwich E, Dahm R, Frank O , Fronhöfer HG et al (2005) beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation. Developmental Biology, 286(2), 391-404.
• Jülich D, Geisler R, Holley SA, Van Bebber F, Busch-Nentwich E, Dahm R, Frank O, Fronhöfer HG, Geiger H, Gilmour D , Hooge J et al (2005) Integrinα5 and delta/notch signaling have complementary spatiotemporal requirements during zebrafish somitogenesis. Developmental Cell, 8(4), 575-586.
• SOLLNER C, RAUCH G, SIEMENS J, GEISLER R, SCHUSTER S, MULLER U, NICOLSON T & CONSORTIUM T (2004) Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells, 428, 955-959.
• Wingert RA, Brownlie A, Galloway JL, Dooley K, Fraenkel P, Axe JL, Davidson AJ, Barut B, Noriega L, Sheng X , Zhou Y et al (2004) The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development, 131(24), 6225-6235.
• Busch-Nentwich E, Söllner C, Roehl H & Nicolson T (2004) The deafness gene dfna5 is crucial for ugdh expression and HA production in the developing ear in zebrafish. Development, 131(4), 943-951.
• Lee JS, Von Der Hardt S, Rusch MA, Stringer SE, Stickney HL, Talbot WS, Geisler R, Nüsslein-Volhard C, Selleck SB, Chien CB & Roehl H (2004) Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer). Neuron, 44(6), 947-960.
• Herzog W, Sonntag C, von der Hardt S, Roehl HH, Varga ZM & Hammerschmidt M (2004) Fgf3 signaling from the ventral diencephalon is required for early specification and subsequent survival of the zebrafish adenohypophysis. Development, 131(15), 3681-3692.
• Ulrich F, Concha ML, Heid PJ, Voss E, Witzel S, Roehl H, Tada M, Wilson SW, Adams RJ, Soll DR & Heisenberg CP (2003) Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development, 130(22), 5375-5384.
• Knaut H, Werz C, Geisler R, Busch-Nentwich E, Dahm R, Frohnhöfer HG, Geiger H, Gilmour D, Holley S, Hooge J , Jülich D et al (2003) A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature, 421(6920), 279-282.
• Habeck H, Odenthal J, Walderich B, Maischein HM, Bebber van F, Busch-Nentwich E, Dahm R, Frohnhöfer HG, Geiger H, Gilmour D , Holley S et al (2002) Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Current Biology, 12(16), 1405-1412.
• Roehl H & Nüsslein-Volhard C (2001) Zebrafish pea3 and erm are general targets of FGF8 signaling. Current Biology, 11(7), 503-507.
• Geisler R, Rauch G-J, Baier H, van Bebber F, Broβ L, Dekens MPS, Finger K, Fricke C, Gates MA, Geiger H , Geiger-Rudolph S et al (1999) A radiation hybrid map of the zebrafish genome. Nature Genetics, 23(1), 86-89.
• Panganiban G, Irvine SM, Lowe C, Roehl H, Corley LS, Sherbon B, Grenier JK, Fallon JF, Kimble J, Walker M , Wray GA et al (1997) The origin and evolution of animal appendages. Proceedings of the National Academy of Sciences of the United States of America, 94(10), 5162-5166.
• Roehl H, Bosenberg M, Blelloch R & Kimble J (1996) Roles of the RAM and ANK domains in signaling by the C.elegans GLP-1 receptor. EMBO Journal, 15(24), 7002-7012.
• Roehl H & Kimble J (1993) Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats. Nature, 364(6438), 632-635.
• Tzung K-W, Lalonde RL, Prummel KD, Mahabaleshwar H, Moran HR, Stundl J, Cass AN, Le Y, Lea R, Dorey K , Tomecka MJ et al () A median fin derived from the lateral plate mesoderm and the origin of paired fins. Nature.
• Balasubramanian M, Baxendale S & Roehl H () Identifying the role of NBAS in bone fragility using zebrafish and exploring therapeutic targets to reverse NBAS activity. Bone Abstracts.
• Tomecka MJ, Ethiraj LP, Sánchez LM, Roehl HH & Carney TJ () Clinical pathologies of bone fracture modelled in zebrafish. Disease Models & Mechanisms.

Conference proceedings papers

• Misra J, Misra J, Mohanty ST, Madan S, Fernandes JA, Ebetino FH, Roehl H, Russell RG & Bellantuono I (2013) Can Bisphosphonates extend Life Span? Effects on Stem Cell survival, DNA Repair and Tissue Regeneration. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 28
• Felber K, Elks P, Croucher P & Roehl H (2009) FGF signalling is regulating bone development in zebrafish. MECHANISMS OF DEVELOPMENT, Vol. 126 (pp S209-S209)
• Knight RD, Mebus K & Roehl HH (2008) Mandibular arch muscle identity is regulated by a conserved molecular process during vertebrate development. JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION, Vol. 310B(4) (pp 355-369)
• Elks PM, Li N, Roehl HH & Croucher PI (2007) WNT signalling upregulates osteoblast differentiation in zebrafish: A novel model for studies in osteoblastogenesis. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 22(7) (pp 1115-1115)

Preprints

• Greaves S, Marsay KS, Monk PN, Roehl H & Partridge LJ () Tetraspanin Cd9b plays a role in fertility in zebrafish, Cold Spring Harbor Laboratory.
• Marsay KS, Greaves S, Mahabaleshwar H, Ho CM, Roehl H, Monk PN, Carney TJ & Partridge LJ () Tetraspanin Cd9b and Cxcl12a/Cxcr4b have a synergistic effect on the control of collective cell migration, Cold Spring Harbor Laboratory.
• Romero MMG, McCathie G, Jankun P & Roehl HH () Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells, Cold Spring Harbor Laboratory.