Presentations
Presentations by invited speakers at the 2007 Workshop.
On
Download the abstracts for the 2007 Workshop presentations (pdf, 372kb), or see Session 1 in detail here.
Session 1: Granulation - The Big Picture
| Author(s) | Affiliation(s) | Presentation |
|---|---|---|
| D. York | Procter and Gamble, UK | AGGLOMERATION AT THE SHARP END – INDUSTRIAL PRACTICE AND NEEDS |
| H. Leuenberger | Institute for Innovation in Industrial Pharmacy, Switzerland | MANUFACTURING PHARMACEUTICAL GRANULES: IS THE GRANULATION END-POINT A MYTH? |
| P. Kleinebudde and C. Reitz | Heinrich-Heine-University Duesseldorf, Germany | SOLID LIPID EXTRUSION FOR THE PRODUCTION OF SUSTAINED RELEASE PELLETS |
| L.X. Liu, R. Smith and J.D. Litster | University of Queensland, Australia | WET GRANULE BREAKAGE IN A BREAKAGE ONLY GRANULATOR: EFFECT OF FORMULATION PROPERTIES ON BREAKAGE BEHAVIOUR |
| G. Frenning, J. Hellström and G. Alderborn | Uppsala University, Sweden | COMPRESSION AND COMPACTION OF BINARY MIXTURES OF GRANULES |
| J.M. Link (1), W. Godlieb (1), P. Tripp (2), N.G. Deen (1), S. Heinrich (3), J.A.M. Kuipers (1), M. Schönherr (4) and M. Peglow (3) | 1) University of Twente, The Netherlands 2) Vibra Maschinenfabrik Schultheis GmbH, Germany 3) Otto-von-Guericke-University Magdeburg,Germany 4) BASF AG Ludwigshafen, Germany |
COMPARISON OF FIBRE OPTICAL MEASUREMENTS AND DISCRETE ELEMENT SIMULATIONS FOR THE STUDY OF GRANULATION IN A SPOUT FLUIDISED BED |
Session 2a: Compaction and Extrusion
| Author(s) | Affiliation(s) | Presentation |
|---|---|---|
| J.P.K.Seville (1), R.F. Mansa (1) and B. Gururajan (2) | 1) Centre for Formulation Engineering, The University of Birmingham 2) Pharmaceutical and Analytical R&D, AstraZeneca |
ROLL PRESSING: THEORY AND APPLICATION |
| B. Gururajan (1,2*), P. Cote (1), N. Turnbull (1), E. Razzano (1) and A.C. Bentham (1) | 1) Pfizer Global Research and Development, UK 2) Medway Sciences & AstraZeneca |
MICRO SCALE PREDICTION OF THE ROLLER COMPACTION PROCESS |
| B Van Melkebeke, C Vervaet and JP Remon | Laboratory of Pharmaceutical Technology, Ghent University, Belgium | VALIDATION OF A CONTINUOUS WET GRANULATION PROCESS USING A TWIN-SCREW EXTRUDER |
Session 2b: Fluidised Bed Processes
| Author(s) | Affiliation(s) | Presentation |
|---|---|---|
| N. Kivikero (1), M. Murtomaa (2), J. Aaltonen (1), K. Kogermann (1,3), E. Räsänen (4), J-P. Mannermaa (5) and A. Juppo (1) | 1) University of Helsinki, Finland 2) University of Turku, Finland 3) University of Tartu, Estonia 4) South Carelian Hospital Pharmacy, Finland 5) Oy Verman Ab, Finland |
FORMULATION AND POLYMORPHIC SCREENING USING MINIATURISED FLUID BED |
| M. Jacob | Glatt Ingenieurtechnik GmbH, Germany | PROCELL-TECHNOLOGY: MODELLING AND APPLICATION |
| M. Peglow (1), S. Heinrich (2) and E. Tsotsas (1) | Otto-von-Guericke University Magdeburg, Germany | TOWARDS A COMPLETE POPULATION BALANCE MODEL FOR FLUIDISED BED SPRAY GRANULATION: SIMULTANEOUS DRYING AND PARTICLE FORMATION |
Session 3a: High Shear Processes 1
| Author(s) | Affiliation(s) | Presentation |
|---|---|---|
| Y. Ouabbas, J. Dodds, A. Chamayou, L. Galet and M. Baron | Ecole Nationale Supérieure des Techniques Industrielles et des Mines d’Albi-Carmaux, France | PARTICLE-PARTICLE COATING IN A CYCLOMIX IMPACT MIXER |
| M. Oullion (1), G.K. Reynolds (2), S. Dilworth (2) and M.J. Hounslow (1) | 1) University of Sheffield, UK 2) AstraZeneca, UK |
DETECTING AND MEASURING NUCLEATION IN HIGH SHEAR GRANULATION |
| K. Saleh, L. Forny, I. Pezron L. Komunjer and P.Guigon | Université de Technologie de Compiègne, France | ENCAPSULATION PROCESS: A WAY TO PRODUCE DRY WATER! |
| Wei-Da Tu, A. Ingram, J. Seville | University of Birmingham, UK | RELATIONS BETWEEN SIZE DISTRIBUTION AND GROWTH BEHAVIOUR IN HIGH-SHEAR MIXER |
Session 3b: Pharmaceutical Granulation 1
| Author(s) | Affiliation(s) | Presentation |
|---|---|---|
| K.P. Hapgood and B. Khanmohammadi | Monash University, Australia | NUCLEATION AND GRANULATION OF HYDROPHOBIC POWDERS |
| G. Walker, S. Bell, M. Vann and G. Andrews | Queens University Belfast, UK | FLUIDISED BED GRANULATION OF PHARMACEUTICAL MATERIALS: CHARACTERISATION USING RAMAN SPECTROSCOPY |
| IC Sinka (1), F Motazedian (1), ACF Cocks (2) and KG Pitt (3) | ) University of Leicester, UK 2) University of Oxford, UK 3) GlaxoSmithKline, Ware, UK |
THE EFFECT OF POWDER FLOW AND DIE FILL ON TABLET PROPERTIES |
| I.N. Björn | AstraZeneca, Sweden | MECHANISTIC BASED PREDICTION OF GRANULATION OUTPUT THROUGH MULTIDIMENSIONAL POPULATION BALANCES AND PAT SENSORS |
Session 4: High Shear Processes 2
| Author(s) | Affiliation(s) | Presentation |
|---|---|---|
| P.R. Mort | Procter & Gamble, USA | SCALE-UP AND CONTROL OF BINDER AGGLOMERATION PROCESSES – BATCH AND CONTINUOUS |
| M. Ghadiri | University of Leeds, UK | EFFECT OF GRANULATION SCALE-UP ON THE STRUCTURE AND STRENGTH OF GRANULES |
| R. Boerefijn | Purac, The Netherlands | A NARROW SIZE DISTRIBUTION ON A HIGH SHEAR MIXER BY APPLYING A FLUX NUMBER APPROACH |
| K van den Dries | Organon, The Netherlands | FREEZING THE HIGH SHEAR GRANULATION PROCESS |
Session 5a: Industrial Granulation
| Author(s) | Affiliation(s) | Presentation |
|---|---|---|
| K. Ax, M. Schoenherr and H. Feise | BASF, Germany | ASPECTS OF INDUSTRIAL GRANULATION |
| S. Palzer | Nestlé Product Technology Centre, Germany | INFLUENCE OF MATERIAL PROPERTIES ON THE AGGLOMERATION OF FOOD PARTICLES |
| T.A. Nagy (1) and Z.G. Meszena (2) | 1) Gedeon Richter Ltd., Hungary 2) Budapest University of Technology, Hungary |
PROCESS PARAMETER ANALYSIS AND PROCESS UNDERSTANDING – SOME INDUSTRIAL EXAMPLES |
| G.M.H. Meesters | DSM Food Specialties, Delft, The Netherlands | DETERMINATION OF THE DRYING CONDITIONS OF STICKY FOOD POWDERS IN A SPRAY DRYER |
Session 5b: Pharmaceutical Granulation 2
| Author(s) | Affiliation(s) | Presentation |
|---|---|---|
| C. Wu and J.P.K. Seville | University of Birmingham, UK | A COMPARATIVE STUDY OF COMPACTION PROPERTIES OF BINARY AND BILAYER TABLETS |
| G.K. Reynolds (1), V.A. Chouk (2), M.J. Hounslow (2) and A.D. Salman (2) | 1) AstraZeneca, UK 2) University of Sheffield, UK |
SINGLE DROP BEHAVIOUR IN A HIGH SHEAR GRANULATOR |
| M. Adams, Siaw Fung Yap*, J. Seville and Z. Zhang | University of Birmingham, UK | COMPACTION OF BINARY MIXTURES OF PHARMACEUTICAL POWDERS |
| M.J. Adams (1), Y.S. Cheong (2), M.J. Hounslow (3) and A.D. Salman (3) | 1) University of Birmingham, UK 2) University of Cambridge, UK 3) University of Sheffield, UK |
MICROSCOPIC INTERPRETATION OF GRANULE STRENGTH IN LIQUID MEDIA |
Session 6: The Micro Scale - Granules and Smaller
| Author(s) | Affiliation(s) | Presentation |
|---|---|---|
| S. Simons (1), S. Germana' (1) and J. Bonsall (2) | 1) University College London, UK 2) Unilever, UK |
REACTIVE BINDERS: WETTABILITY AND ADHESION BEHAVIOUR IN DETERGENT GRANULATION |
| S. Dorvlo (1), M. Hartmann (2), S. Palzer (2) and A.D. Salman (1) | 1) University of Sheffield, UK 2) Nestlé, Germany |
SURFACE AND WETTING ANALYSIS: AN INSIGHT INTO THE PRODUCTS OF GRANULATION |
| F. Stepanek (1), M. Ansari (1) and P. Rajniak (2) | 1) Imperial College London, UK 2) Merck & Co, Inc., USA |
MECHANISTIC MODELING OF THE FORMATION AND DISSOLUTION OF MULTI-COMPONENT GRANULES |