Dr Pinaki Bhattacharya

School of Mechanical, Aerospace and Civil Engineering

Senior Lecturer in Solid Biomechanics

p.bhattacharya@sheffield.ac.uk
+44 114 222 0156

Sir Frederick Mappin Building

Full contact details

Dr Pinaki Bhattacharya
School of Mechanical, Aerospace and Civil Engineering
Sir Frederick Mappin Building
Mappin Street
Sheffield
S1 3JD

Profile

Dr Pinaki Bhattacharya is a Lecturer in Solid Biomechanics in the Department of Mechanical Engineering and in the Insigneo Institute for in silico Medicine at the University of Sheffield.

Pinaki Bhattacharya obtained his doctoral degree, specialising in biomechanics (2012) from Purdue University (West Lafayette, USA). From 2012 to 2018, he further developed experimental and computational approaches in biomechanical applications during post-doctoral positions held at KU Leuven (Leuven, Belgium) and at the University of Sheffield.

Previously, he obtained his undergraduate and postgraduate degrees from India, in naval architecture (2001) and in engineering mechanics (2008) respectively, from the Indian Institute of Technology (Kharagpur) and the Jawaharlal Nehru Centre for Advanced Scientific Research (Bangalore). From 2001 to 2005, he worked in the CAE software industry (Pune) and as a research assistant in turbulent heat transfer (Indian Institute of Science, Bangalore).

His current research interest is aimed at predicting the efficacy of medical interventions in altering disease outcomes, especially in musculoskeletal diseases such as osteoporosis. To this end, he is developing mechanistic theories of disease progression, with a focus on capturing the complexity across scales of time and space.

Pinaki Bhattacharya is also teaching modules on Medical Device Regulation and Anatomy and Physiology within MEng (Mechanical Engineering with Biomechanics, Biomaterials and Bioengineering) and MSc (Computational Medicine) programmes.

Publications

Journal articles

Moraiti S, Cheong VS, Dall’Ara E, Kadirkamanathan V & Bhattacharya P (2024) A novel framework for elucidating the effect of mechanical loading on the geometry of ovariectomized mouse tibiae using principal component analysis. Frontiers in Bioengineering and Biotechnology, 12. View this article in WRRO
Aldieri A, Paggiosi M, Eastell R, Bignardi C, Audenino AL, Bhattacharya P & Terzini M (2024) DXA-based statistical models of shape and intensity outperform aBMD hip fracture prediction: A retrospective study. Bone, 182, 117051-117051.
Li J, Viceconti M, Li X, Bhattacharya P, Naimark DMJ & Osseyran A (2023) Cost-Effectiveness Analysis of CT-Based Finite Element Modeling for Osteoporosis Screening in Secondary Fracture Prevention: An Early Health Technology Assessment in the Netherlands. MDM Policy & Practice, 8(2).
Gupta A, Maslen C, Vindlacheruvu M, Abel RL, Bhattacharya P, Bromiley PA, Clark EM, Compston JE, Crabtree N, Gregory JS , Kariki EP et al (2022) Digital health interventions for osteoporosis and post-fragility fracture care. Therapeutic Advances in Musculoskeletal Disease, 14.
Aldieri A, Terzini M, Audenino AL, Bignardi C, Paggiosi M, Eastell R, Viceconti M & Bhattacharya P (2022) Personalised 3D assessment of trochanteric soft tissues improves HIP fracture classification accuracy. Annals of Biomedical Engineering, 50(3), 303-313.
Aldieri A, Bhattacharya P, Paggiosi M, Eastell R, Audenino AL, Bignardi C, Morbiducci U & Terzini M (2022) Improving the Hip Fracture Risk Prediction with a Statistical Shape-and-Intensity Model of the Proximal Femur. Annals of Biomedical Engineering.
Harvey NC, Poole KE, Ralston SH, McCloskey EV, Sangan CB, Wiggins L, Jones C, Gittoes N, Compston J, Abrahamsen B , Gregson C et al (2022) Towards a cure for osteoporosis: the UK Royal Osteoporosis Society (ROS) Osteoporosis Research Roadmap. Archives of Osteoporosis, 17(1).
Benemerito I, Griffiths W, Allsopp J, Furnass W, Bhattacharya P, Li X, Marzo A, Wood S, Viceconti M & Narracott A (2021) Delivering computationally-intensive digital patient applications to the clinic: An exemplar solution to predict femoral bone strength from CT data. Computer Methods and Programs in Biomedicine, 208. View this article in WRRO
Taylor M, Viceconti M, Bhattacharya P & Li X (2021) Finite element analysis informed variable selection for femoral fracture risk prediction. Journal of the Mechanical Behavior of Biomedical Materials.
Aggarwal V, Maslen C, Abel RL, Bhattacharya P, Bromiley PA, Clark EM, Compston JE, Crabtree N, Gregory JS, Kariki EP , Harvey NC et al (2021) Opportunistic diagnosis of osteoporosis, fragile bone strength and vertebral fractures from routine CT scans; a review of approved technology systems and pathways to implementation. Therapeutic Advances in Musculoskeletal Disease, 13, 1759720X2110240-1759720X2110240.
Subramani R, Izquierdo-Alvarez A, Bhattacharya P, Meerts M, Moldenaers P, Ramon H & Van Oosterwyck H (2020) The influence of swelling on elastic properties of polyacrylamide hydrogels. Frontiers in Materials, 7. View this article in WRRO
Shuaib A, Motan D, Bhattacharya P, McNabb A, Skerry TM & Lacroix D (2019) Heterogeneity in the mechanical properties of integrins determines mechanotransduction dynamics in bone osteoblasts. Scientific Reports, 9(1). View this article in WRRO
Bhattacharya P, Altai Z, Qasim M & Viceconti M (2019) A multiscale model to predict current absolute risk of femoral fracture in a postmenopausal population. Biomechanics and Modeling in Mechanobiology, 18(2), 301-318. View this article in WRRO
Viceconti M, Qasim M, Bhattacharya P & Li X (2018) Correction to: Are CT-Based Finite Element Model Predictions of Femoral Bone Strength Clinically Useful?. Current Osteoporosis Reports.
Bhattacharya P, Betts D & van Lenthe GH (2018) A novel contact interaction formulation for voxel‐based micro‐finite‐element models of bone. International Journal for Numerical Methods in Engineering, 115(4), 411-426. View this article in WRRO
Viceconti M, Qasim M, Bhattacharya P & Li X (2018) Are CT-Based Finite Element Model Predictions of Femoral Bone Strengthening Clinically Useful?. Current Osteoporosis Reports, 16(3), 216-223. View this article in WRRO
Heck T, Smeets B, Vanmaercke S, Bhattacharya P, Odenthal T, Ramon H, Van Oosterwyck H & Van Liedekerke P (2017) Modeling extracellular matrix viscoelasticity using smoothed particle hydrodynamics with improved boundary treatment. Computer Methods in Applied Mechanics and Engineering, 322, 515-540. View this article in WRRO
Bhattacharya P & Viceconti M (2017) Multiscale modelling methods in biomechanics. Wiley Interdisciplinary Reviews: Systems Biology and Medicine. View this article in WRRO
Leonidakis KA, Bhattacharya P, Patterson J, Vos BE, Koenderink GH, Vermant J, Lambrechts D, Roeffaers M & Van Oosterwyck H (2017) Fibrin structural and diffusional analysis suggests that fibers are permeable to solute transport. Acta Biomaterialia, 47, 25-39. View this article in WRRO
Bhattacharya P, Kelleher JE & Siegmund T (2015) Role of gradients in vocal fold elastic modulus on phonation. Journal of Biomechanics, 48(12), 3356-3363. View this article in WRRO
Camargos GV, Bhattacharya P, van Lenthe GH, Del Bel Cury AA, Naert I, Duyck J & Vandamme K (2015) Mechanical competence of ovariectomy-induced compromised bone after single or combined treatment with high-frequency loading and bisphosphonates. Scientific Reports, 5(1). View this article in WRRO
Bhattacharya P & Siegmund T (2015) The role of glottal surface adhesion on vocal folds biomechanics. Biomechanics and Modeling in Mechanobiology, 14(2), 283-295. View this article in WRRO
Jugdaohsingh R, Watson AIE, Bhattacharya P, van Lenthe H & Powell JJ (2015) Positive association between serum silicon levels and bone mineral density in female rats following oral silicon supplementation with monomethylsilanetriol. Osteoporosis International, 26(4), 1405-1415. View this article in WRRO
Bhattacharya P & Siegmund T (2014) A computational study of systemic hydration in vocal fold collision. Computer Methods in Biomechanics and Biomedical Engineering, 17(16), 1835-1852. View this article in WRRO
Bhattacharya P & Siegmund T (2014) Computational modeling of vibration-induced systemic hydration of vocal folds over a range of phonation conditions. International Journal for Numerical Methods in Biomedical Engineering, 30(10), 1019-1043. View this article in WRRO
Bhattacharya P & Siegmund T (2014) Validation of a flow-structure-interaction computation model of phonation. Journal of Fluids and Structures, 48, 169-187. View this article in WRRO
Bhattacharya P & Siegmund T (2014) Computational modeling of vibration-induced systemic hydration of vocal folds over a range of phonation conditions. International Journal for Numerical Methods in Biomedical Engineering, 30(10), 1019-1043.
Bhattacharya P & Siegmund TH (2012) A Canonical Biomechanical Vocal Fold Model. Journal of Voice, 26(5), 535-547. View this article in WRRO
BHATTACHARYA P, MANOHARAN MP, GOVINDARAJAN R & NARASIMHA R (2006) The critical Reynolds number of a laminar incompressible mixing layer from minimal composite theory. Journal of Fluid Mechanics, 565, 105-105.
Bhattacharya P, Li Q, Lacroix D, Kadirkamanathan V & Viceconti M () A systematic approach to the scale separation problem in the development of multiscale models. PLOS ONE, 16(5), e0251297-e0251297.
Pascoletti G, Aldieri A, Terzini M, Bhattacharya P, Calì M & Zanetti EM () Stochastic PCA-Based Bone Models from Inverse Transform Sampling: Proof of Concept for Mandibles and Proximal Femurs. Applied Sciences, 11(11), 5204-5204.

Chapters

(2015) 9 Biomechanics of Trabecular and Cortical Bone, Experimental Research Methods in Orthopedics and Trauma Georg Thieme Verlag
van Lenthe GH & Bhattacharya P (2015) Biomechanics of trabecular and cortical bone In Simpson H & Augat P (Ed.), Experimental research methods: a guidebook for studies in trauma care (pp. 64-64). Stuttgart: Thieme Medical Publishers.
Bhattacharya P & Van Lenthe GH (2014) Experimental quantification of bone mechanics, Bone Substitute Biomaterials (pp. 30-71). Elsevier

Conference proceedings papers

Gupta A, Maslen C, Vindlacheruvu M, Abel R, Bhattacharya P, Bromiley P, Clark E, Compston J, Crabtree N, Gregory J , Kairki E et al (2022) Digital Health Interventions for Osteoporosis and Post-Fragility Fracture Care. JOURNAL OF BONE AND MINERAL RESEARCH, Vol. 37 (pp 184-184)
Bhattacharya P & Siegmund TH (2011) Determination of Mechanical Stresses in Vibration and Contact During Flow-Structure-Interaction in Vocal Folds. ASME 2011 Summer Bioengineering Conference, Parts A and B, 22 June 2011 - 25 June 2011.
Bhattacharya P, Govindarajan R, Narasimha R, Siddiqi AH, Brokate M & Gupta AK (2009) In What Sense is a Low-Reynolds Mixing Layer Stable?. AIP Conference Proceedings

Datasets

Bhattacharya P, Viceconti M & Tai ZA Data for paper "A multiscale model to predict current absolute risk of femoral fracture in a postmenopausal population".
Bhattacharya P, Li Q, Lacroix D, Kadirkamanathan V & Viceconti M Data for manuscript titled "A systematic approach to the scale separation problem in the development of multiscale models".