Nyasha Mafirakureva
Population Health, School of Medicine and Population Health
Research Fellow
+44 114 225 9137
Full contact details
Population Health, School of Medicine and Population Health
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
- Profile
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I joined the Health Economics and Decision Science (HEDS) section of the School of Health and Related Research (ScHARR) as Research Fellow in Health Economics and Decision Modelling in January 2019. I’m currently working on economic evaluation of clinical trials evaluating various paediatric tuberculosis interventions in lower-middle income countries (LMIC). Previously I worked at the University of Bristol, UK where I was involved in evaluating the impact and cost-effectiveness of interventions for hepatitis C virus in low and middle-income countries. Since 2011, I have been carrying out economic evaluation projects in Cambodia, Cameroon, Ireland, Kenya, Myanmar, Pakistan, Uganda, South Africa and Zimbabwe.
- Research interests
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My research interests include economic evaluations of interventions to improve infectious disease control and decision-analytic modelling for cost-effectiveness analysis.
Current Projects
- Cap-TB and TB SPEED projects on interventions for paediatric TB (UNITAID)
- Fractures in Sub-Saharan Africa: epidemiology, economic impact and ethnography (FRACTURES-E3) – Wellcome Trust
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- Cost-effectiveness of community-based household tuberculosis contact management for children in Cameroon and Uganda: a modelling analysis of a cluster-randomised trial. The Lancet Global Health, 11(12), e1922-e1930.
- Cost-effectiveness analysis of interventions to improve diagnosis and preventive therapy for paediatric tuberculosis in 9 sub-Saharan African countries: A modelling study. PLOS Medicine, 20(9). View this article in WRRO
- Xpert ultra stool testing to diagnose tuberculosis in children in Ethiopia and Indonesia: a model-based cost-effectiveness analysis. BMJ Open, 12(7). View this article in WRRO
- The global impact of household contact management for children on multidrug-resistant and rifampicin-resistant tuberculosis cases, deaths, and health-system costs in 2019: a modelling study. The Lancet Global Health. View this article in WRRO
- Cost-effectiveness of mass screening for Hepatitis C virus among all inmates in an Irish prison. International Journal of Drug Policy, 96. View this article in WRRO
- An intensive model of care for hepatitis C virus screening and treatment with direct‐acting antivirals in people who inject drugs in Nairobi, Kenya : a model‐based cost‐effectiveness analysis. Addiction.
- Cost‐effectiveness of screening and treatment using direct‐acting antivirals for chronic Hepatitis C virus in a primary care setting in Karachi, Pakistan. Journal of Viral Hepatitis.
- Cost and cost‐effectiveness of a simplified treatment model with direct‐acting antivirals for chronic hepatitis C in Cambodia. Liver International, 40(10), 2356-2366.
- Effects and cost of different strategies to eliminate hepatitis C virus transmission in Pakistan: a modelling analysis. The Lancet Global Health, 8(3), e440-e450. View this article in WRRO
- Cost effectiveness of adding nucleic acid testing to hepatitis B, hepatitis C, and human immunodeficiency virus screening of blood donations in Zimbabwe. Transfusion, 56(12), 3101-3111.
- A systematic approach for reviewing research capacity within Zimbabwe's national blood service. ISBT Science Series, 11(2), 110-117.
- The costs of producing a unit of blood in Zimbabwe. Transfusion, 56(3), 628-636.
- Health-related quality of life in HIV/AIDS patients on antiretroviral therapy at a tertiary care facility in Zimbabwe. AIDS Care, 28(7), 904-912.
- Profiles of blood and blood component transfusion recipients in Zimbabwe. Blood Transfusion, 13(4), 600-609.
- The healthcare system costs of hip fracture care in South Africa. Osteoporosis International.
Preprints
All publications
Journal articles
- Household contact management and preventive treatment for drug-resistant tuberculosis. The Lancet Global Health, 12(9), e1387-e1388.
- Integration of HIV Testing in a Community Intervention for Tuberculosis Screening Among Household Contacts of Patients with Tuberculosis in Cameroon and Uganda. JAIDS Journal of Acquired Immune Deficiency Syndromes, 95(5), 431-438.
- Cost-effectiveness and budget impact of decentralising childhood tuberculosis diagnosis in six high tuberculosis incidence countries: a mathematical modelling study. EClinicalMedicine, 102528.
- Effectiveness of a community-based approach for the investigation and management of children with household tuberculosis contact in Cameroon and Uganda: a cluster-randomised trial. The Lancet Global Health, 11(12), e1911-e1921.
- Cost-effectiveness of community-based household tuberculosis contact management for children in Cameroon and Uganda: a modelling analysis of a cluster-randomised trial. The Lancet Global Health, 11(12), e1922-e1930.
- Cost-effectiveness analysis of interventions to improve diagnosis and preventive therapy for paediatric tuberculosis in 9 sub-Saharan African countries: A modelling study. PLOS Medicine, 20(9). View this article in WRRO
- Evaluating change in a pressured healthcare system: a cross-sectional study of implementation outcomes using routine data indicators and proxies. Implementation Science Communications, 4(1). View this article in WRRO
- Fractures in sub-Saharan Africa: epidemiology, economic impact and ethnography (Fractures-E3): study protocol. Wellcome Open Research, 8. View this article in WRRO
- Modelling the impact of HIV and hepatitis C virus prevention and treatment interventions among people who inject drugs in Kenya. AIDS, 36(15), 2191-2201. View this article in WRRO
- Xpert ultra stool testing to diagnose tuberculosis in children in Ethiopia and Indonesia: a model-based cost-effectiveness analysis. BMJ Open, 12(7). View this article in WRRO
- The global impact of household contact management for children on multidrug-resistant and rifampicin-resistant tuberculosis cases, deaths, and health-system costs in 2019: a modelling study. The Lancet Global Health. View this article in WRRO
- Feasibility of a randomized clinical trial evaluating a community intervention for household tuberculosis child contact management in Cameroon and Uganda. Pilot and Feasibility Studies, 8. View this article in WRRO
- Cost-effectiveness of mass screening for Hepatitis C virus among all inmates in an Irish prison. International Journal of Drug Policy, 96. View this article in WRRO
- An intensive model of care for hepatitis C virus screening and treatment with direct‐acting antivirals in people who inject drugs in Nairobi, Kenya : a model‐based cost‐effectiveness analysis. Addiction.
- Progress on the elimination of viral hepatitis in Zimbabwe: A review of the policies, strategies and challenges. Journal of Viral Hepatitis, 28(7), 994-1002.
- Cost and cost-effectiveness of a real-world HCV treatment program among HIV-infected individuals in Myanmar. BMJ Global Health, 6(2).
- Cost‐effectiveness of screening and treatment using direct‐acting antivirals for chronic Hepatitis C virus in a primary care setting in Karachi, Pakistan. Journal of Viral Hepatitis.
- Cost and cost‐effectiveness of a simplified treatment model with direct‐acting antivirals for chronic hepatitis C in Cambodia. Liver International, 40(10), 2356-2366.
- Modelling the cost of hepatitis C virus transmission in Pakistan. Journal of Hepatology, 73, S791-S791.
- Cost-effectiveness of screening and treatment using direct-acting antivirals for chronic hepatitis C virus in low- and middle-income settings. Journal of Hepatology, 73, S812-S813.
- Cost-effectiveness of mass screening for HCV in an Irish prison. Journal of Hepatology, 73, S832-S832.
- Comparison of costs of different HCV screening and linkage to care interventions across Europe. Journal of Hepatology, 73, S825-S825.
- Integrating pediatric TB services into child healthcare services in Africa: study protocol for the INPUT cluster-randomized stepped wedge trial. BMC Public Health, 20(1).
- Effects and cost of different strategies to eliminate hepatitis C virus transmission in Pakistan: a modelling analysis. The Lancet Global Health, 8(3), e440-e450. View this article in WRRO
- Fragility fractures in sub-Saharan Africa : time to break the myth. The Lancet Global Health, 7(1), e26-e27.
- Cost effectiveness of adding nucleic acid testing to hepatitis B, hepatitis C, and human immunodeficiency virus screening of blood donations in Zimbabwe. Transfusion, 56(12), 3101-3111.
- A systematic approach for reviewing research capacity within Zimbabwe's national blood service. ISBT Science Series, 11(2), 110-117.
- Erratum. Transfusion, 56(7), 1920-1920.
- The costs of producing a unit of blood in Zimbabwe. Transfusion, 56(3), 628-636.
- Health-related quality of life in HIV/AIDS patients on antiretroviral therapy at a tertiary care facility in Zimbabwe. AIDS Care, 28(7), 904-912.
- Profiles of blood and blood component transfusion recipients in Zimbabwe. Blood Transfusion, 13(4), 600-609.
- Incidence and pattern of 12 years of reported transfusion adverse events in Zimbabwe: A retrospective analysis. Blood Transfusion, 12(3), 362-367.
- Population Pharmacokinetic-Pharmacodynamic Modeling of Haloperidol in Patients With Schizophrenia Using Positive and Negative Syndrome Rating Scale. Journal of Clinical Psychopharmacology, 33(6), 731-739.
- A cost analysis of a simplified model for HCV screening and treatment at a tertiary hospital in Zimbabwe. Expert Review of Pharmacoeconomics & Outcomes Research, 1-9.
- A SITUATIONAL AND STAKEHOLDER ANALYSIS OF HEALTH TECHNOLOGY ASSESSMENT IN ZIMBABWE. International Journal of Technology Assessment in Health Care, 1-26.
- Household costs incurred under community- and facility-based service-delivery models of tuberculosis preventive therapy for children: a survey in Cameroon and Uganda. Journal of Global Health Reports, 7.
- Household costs incurred when seeking and receiving paediatric tuberculosis services: a survey in Cameroon and Kenya. Journal of Global Health Reports, 7.
- The healthcare system costs of hip fracture care in South Africa. Osteoporosis International.
- Integrating Hepatitis C Care for Opioid Substitution Treatment Patients Attending General Practice: Feasibility, Clinical, and Cost-Effectiveness Analysis. Interactive Journal of Medical Research, 11(2), e35300-e35300.
Chapters
Conference proceedings papers
- Assessment of the Costs and outcomes of Antiretroviral Therapy In Adult Outpatients at a Tertiary Hospital In Harare, Zimbabwe. Value in Health, Vol. 18(3) (pp A236-A236)
Preprints
- Cost-effectiveness and budget impact of decentralising childhood tuberculosis diagnosis: a mathematical modelling study in six high tuberculosis incidence countries, Cold Spring Harbor Laboratory.
- Evaluating Change in a Degraded Healthcare System: A Cross-Sectional Study of Implementation Outcomes using Routine Data Indicators and Proxies., Research Square Platform LLC.
- Modelling the Impact of Prevention and Treatment Interventions on HIV and Hepatitis C Virus Transmission Among People Who Inject Drugs in Kenya, Cold Spring Harbor Laboratory.
- Cost-effectiveness of community-based household tuberculosis contact management for children in Cameroon and Uganda: a modelling analysis of a cluster-randomised trial. The Lancet Global Health, 11(12), e1922-e1930.
- Teaching interests
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Economic Evaluation and Health Care Financing
Dissertation supervision
- Professional activities and memberships
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Member of International Society for Pharmacoeconomics and Outcome Research (ISPOR).
Member of International Society for Pharmacoeconomics and Outcome Research (ISPOR) South African Chapter.
Member of Public Health Association of South Africa.