Bone and joint interventions

We use multi-disciplinary approaches including cell cultures, animal models, and predictive computational models to study the effects of biomechanical and biochemical treatments on the competence of musculoskeletal tissues and organs, to move towards a personalised medicine-oriented approach.

3D diagram of pedicle screws in a vertebra
Effect of size of pedicle screws on the deformation of the human vertebra
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We use our expertise in multi-scale experimental and computational biomechanics to study many research areas that are covered by this priority, including

  • orthopaedic biomechanics and the testing and development of medical devices 
  • characterization and testing of biomaterials like scaffolds, injectables, and coatings, both alone and in combination with cell and gene therapy approaches
  • developing intact tissue models and maintaining cellular cross-talk
  • monitoring the effect of combined pharmacological and lifestyle interventions
  • patient stratification and personalised medicine

Centres of excellence

The University's cross-faculty research centres harness our interdisciplinary expertise to solve the world's most pressing challenges.