Our publications
Publications by Sheffield academics whose research interests include the theme of 'Translational and precision cancer medicine'.
Publications
Journal articles
- Malignant transformation of verrucous oral potentially malignant disorders at a tertiary referral centre: A retrospective cohort study. Oral Oncology, 180, 108040-108040.
- MOFs, COFs, and HOFs. Coordination Chemistry Reviews, 560, 217805-217805.
- Functional roles for FEN1 phosphate steering residues in multi-step substrate verification prior to reaction. Journal of Biological Chemistry, 113225-113225.
- Strong correlation between phantomless and inline phantom-based densitometric calibration of vertebral properties from CT scans of healthy volunteers. Frontiers in Bioengineering and Biotechnology, 14. View this article in WRRO
- Role of neutropenic diet in prevention of infection and graft-versus-host disease in haematopoietic stem cell transplant recipients: systematic review and meta-analysis protocol. Frontiers in Nutrition, 13. View this article in WRRO
- Development of a Cu‐Catalyzed Regioselective Hydrazidation of 1,2‐Diborylalkenes. Advanced Synthesis & Catalysis, 368(10).
- Cardio-oncology research prioritisation in the United Kingdom: national surveys of health care professionals, patients and carers. Cardio-Oncology. View this article in WRRO
- Broadening the Inherited ASXL3 Spectrum and Unveiling Molecular Mechanisms through Detailed Genotypic-Phenotypic Analyses. Genetics in Medicine Open, 104409-104409.
- A bioactive hydrogel harnessing the regenerative potential of notochordal cells serves as instructive cell carrier for nucleus pulposus repair. Biomaterials, 328, 123895-123895.
- Loss of Cathepsin Z enhances pro-inflammatory macrophage responses and promotes tissue regeneration in zebrafish. Disease Models & Mechanisms, dmm.052520.
- Multi-site validation of an AI-based biomarker test for determining ER, PR, and HER2 status from H&E-stained breast cancer slides. ESMO Real World Data and Digital Oncology, 12, 100702-100702.
- Thermal and chemical control of emission and excited-state dynamics in non-(TMS)3P-derived InP quantum dots.. J Chem Phys, 164(14).
- A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section. JOR SPINE, 9(2).
- Nonanoic acid-containing polymethyl methacrylate denture base inhibits Candida albicans growth and biofilm formation. Journal of Dentistry, 106685-106685.
- Biallelic variants in the noncoding RNA gene RNU4-2 cause a recessive neurodevelopmental syndrome with distinct white matter changes.. Nat Genet.
- A scoping review investigating the influence of comorbidities on the use and outcomes of biological therapies in breast cancer.. J Geriatr Oncol, 17(4), 102964.
- EX VIVO EXPLORATION OF PCRX-201 IN HUMAN KNEE OSTEOARTHRITIS TISSUES. Osteoarthritis and Cartilage, 34, S315-S315.
- Using Mesendoderm Progenitor Cells Seeded in Hydrogel Biomaterial as a strategy to Regenerate the Intervertebral disc. Osteoarthritis and Cartilage, 34, S316-S317.
- Acetyl-Phosphate Dependent Protein Acetylation in Neisseria gonorrhoeae.. Microbiologyopen, 15(2), e70231.
- Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro. JOR SPINE, 9(2).
- A Network-Based Approach to Understanding Key Signaling Pathways in Intervertebral Disc Biology. JOR SPINE, 9(2).
- Assessing frailty in aged zebrafish using a quick pseudo-frailty index. Biology Open. View this article in WRRO
- NICE 2026 guideline for the diagnosis and management of kidney cancer. The Lancet Oncology, 27(4), 405-408.
- An extraction pipeline for analysis of hematopoietic stem cell transplantation data.. Bone Marrow Transplant.
- A Biocompatible and Flexible medium chain length PHA, P(3HB-co-20mol%3HHx) for Neural Tissue Engineering. Journal of Biotechnology.
- Innovative P(3HB)/carbon-based material composites for bone tissue regeneration: Biocompatibility, thermo-mechanical, and structural insights. Materials Today Advances, 29.
- Translating in vitro buccal permeation to in vivo and whole‑body exposure using in silico cell‑based and physiologically-based pharmacokinetic modelling.. Int J Pharm, 126701.
- Immune-adaptive pathogen variation reveals targetable mediators of gram-positive bacterial killing in macrophages.. Sci Adv, 12(9), eaea0375.
- Proton-coupled electron transfer from the hydride perspective: resolving metal oxidation and protonation in a hydridocarbonyl complex by 2D-IR spectroelectrochemistry. The Journal of Physical Chemistry Letters, 17(10), 3008-3012. View this article in WRRO
- Adult survivors of sickle cell disease, transfusion-dependent beta-thalassaemia and childhood acute leukaemia in England: protocol for a mixed methods data linkage and health-related quality of life survey study. BMJ Open, 16(2), e111664-e111664.
- 3D environment favors persistent changes in cell functions and altered morphology, wrinkling, and biomechanical signature of the nucleus. Cell Reports Physical Science, 7(2), 103116-103116.
- Doxorubicin induces bone loss and modifies multiple cell populations in vivo – Implications for modelling of bone metastasis. Journal of Bone Oncology, 56, 100736-100736.
- Co-solute Effects Reveal the Nature of Weak Forces Governing GLP-1 Oligomers Stability. Journal of Biological Chemistry, 111223-111223.
- A Pilot Project to Evaluate the Benefit of Additional Support in Haematopoietic Cell Transplant (HCT) Research Data Management on Behalf of Anthony Nolan and BSBMTCT. eJHaem, 7(1).
- Aptamer-mediated targeted approach to disrupt oncogenic HSP90α. International Journal of Biological Macromolecules, 347, 150576-150576.
- Complex Mechanical Loading and Pro‐Inflammatory Cytokines in Intervertebral Disc Degeneration. JOR SPINE, 9(1).
- Improving rigor and reproducibility through implementation of the ISSCR standards for human stem cell use in research. Stem Cell Reports, 102780-102780.
- Feasibility and Implementation of INTERVAL-GAP4: A Global Randomised Controlled Trial of Intense Hybrid-supervised/Self-managed Versus Self-directed Exercise for Metastatic Prostate Cancer. European Urology Open Science, 84, 29-39.
- Perspectives from the 2025 ISCBI/ISCI joint workshop on genetic stability, clonal monitoring, ethical data governance, and global inclusion in stem cell banking. Stem Cell Research and Therapy, 17(1).
- Oropharyngeal squamous cell carcinoma associated with human papilloma virus. Dental Update, 53(1), 46-52.
- Differential diagnosis of blistering disorders presenting in the oral cavity. Diagnostic Histopathology.
- Protocol to identify mechanosensitive nuclear proteins using tunable actomyosin contractility and proximity biotinylation in mammalian cells. STAR Protocols, 7(1), 104288-104288.
- Implications of genetic and epigenetic aberrations to the tumorigenicity of human pluripotent stem cells. Advanced Drug Delivery Reviews, 228, 115743-115743.
- Understanding the Physiological Behavior of Disc Cells in an In Vitro Imitation of the Healthy and Degenerated Disc Niche.. JOR Spine, 8(4), e70153.
- Re: Rebecca Voelker. What Is Prostate Cancer? JAMA. In press. https://doi.org/10.1001/jama.2025.10177. European Urology.
- Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study. European Urology Focus.
- Gene-specific growth charts for ASXL3-related disorder. American Journal of Medical Genetics Part A. View this article in WRRO
- RESECT: A Randomised Controlled Trial of Audit and Feedback in Non–muscle-invasive Bladder Cancer Surgery. European Urology.
- Exciting Times in Urological Oncology: Rapid Advances and Greater Complexity Are Changing Practice and Improving Outcomes. European Urology Focus.
- Nanoparticle platforms for encapsulation of therapeutic deep eutectic systems to target colorectal cancer cells. Journal of Drug Delivery Science and Technology, 114, 107517-107517.
- Analysis of mRNA multimerisation (aggregation) using non-denaturing ion-pair reversed-phase liquid chromatography. Journal of Chromatography A, 466653-466653.
- Intracellular Detection of
C. acnes
and
S. aureus
in Non‐Herniated Human Intervertebral Discs: Implications for Catabolic Signaling Pathways. JOR SPINE, 8(4).
- Editorial: In vitro transcription (IVT) reaction – the gateway to new therapeutic modalities. Frontiers in Molecular Biosciences, 12. View this article in WRRO
- Turning the tide: harnessing vaccines and viruses to fight cancer. Immunotherapy Advances. View this article in WRRO
- Immune-based risk score derived from bulk and single-cell transcriptomics enhances prognostic stratification in MDS. Blood, 146(Supplement 1), 115-115.
- Inflammatory and metabolic gene signatures predict overall survival and response to venetoclax-based therapy in TP53 mutant AML. Blood, 146(Supplement 1), 1734-1734.
- Team familiarity: Renal, bladder and p;rostate cancer surgery outcomes with respect to team composition. European Urology Open Science, 81, S346-S346.
- Health-related quality of life in muscle invasive bladder cancer patients receiving radical surgery versus those who do not: A real-world survey. European Urology Open Science, 81, S413-S414.
- Non–muscle-invasive Bladder Cancer: Many New Options, If You Can Afford Them. European Urology.
- Base-Mediated Annulation Strategy to Naphthol Boronic Ester Derivatives.. J Org Chem.
- DEVELOPMENT OF AN EX VIVO OSTEOARTHRITIC KNEE MODEL. Orthopaedic Proceedings, 107-B(SUPP_9), 82-82.
- SUN-744 Family mapping of previously identified patients with pathogenic or likely pathogenic ALPL variants using predictive genotyping and detailed phenotyping approach: the FAME case-control study. Journal of the Endocrine Society, 9(Supplement_1). View this article in WRRO
- Correction: A subset of neutrophil phagosomes is characterised by pulses of Class I PI3K activity. Disease Models & Mechanisms, 18(10).
- SIMULATING INTRACELLULAR SIGNALLING PATHWAYS IN INTERVERTEBRAL DISC HOMEOSTASIS AND DEGENERATION. Orthopaedic Proceedings, 107-B(SUPP_9), 54-54.
- Development of a community research link worker role to enable culturally tailored research and empower marginalised communities to participate: the IBISES model. Research Involvement and Engagement, 11. View this article in WRRO
- Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics. The FEBS Journal. View this article in WRRO
- Cancer cell dormancy in the bone microenvironment. Current Osteoporosis Reports, 23(1). View this article in WRRO
- The LMSz method - an automatable scalable approach to constructing gene-specific growth charts in rare disorders. European Journal of Human Genetics. View this article in WRRO
- 36International neoadjuvant kidney cancer consortium guidelines on assessing pathological response after neoadjuvant therapy in kidney cancer. The Oncologist, 30(Supplement_2).
- Revisiting Neoadjuvant Chemotherapy in Cisplatin-eligible Muscle-invasive Bladder Cancer. European Urology Oncology.
- Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer. Nature Communications, 16(1). View this article in WRRO
- Erdafitinib in Patients with High- and Intermediate-risk Non–muscle-invasive Bladder Cancer: Final Analysis of THOR-2 Study. European Urology.
- Interventions for patients with prostate cancer on active surveillance: a narrative review. BJU International. View this article in WRRO
- Revisiting the genetics of hypophosphatasia. Journal of Inherited Metabolic Disease, 48(6). View this article in WRRO
- P12.58.A ROLE OF IL-33/ST2 AXIS IN GLIOBLASTOMA DEVELOPMENT AND ITS RESPONSE TO TREATMENT. Neuro-Oncology, 27(Supplement_3), iii130-iii130.
- Harnessing Artificial Intelligence in Head and Neck Oncology Practice. Otolaryngologic Clinics of North America.
- Ward AdmiSsion of Haematuria, an Observational mUlticentre sTudy: patient-level analysis (WASHOUT). European Urology Open Science, 80, S8-S8.
- Surgical Interventions Improve Survival in Patients with Metastatic Uveal Melanoma. Clinical Surgical Oncology, 100102-100102.
- Results from a UK consensus via Delphi on practical considerations surrounding risk assessment and patient monitoring for a prompt diagnosis of severe veno‐occlusive disease (VOD) in adults post‐HSCT. eJHaem, 6(5). View this article in WRRO
- Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer. Science Signaling, 18(906).
- Novel polyhydroxyalkanoate–graphene oxide composites with potential for clinical application against bacterial implant-associated infections in septic surgery. Frontiers in Bioengineering and Biotechnology, 13. View this article in WRRO
- The potential role of misfolded wild-type SOD1 protein in sporadic amyotrophic lateral sclerosis (ALS): a review of the evidence. Neurobiology of Disease, 216, 107124-107124.
- Genetic susceptibility and environmental risk factors in bladder cancer: evidence from the UK biobank. Bladder Cancer, 11(3). View this article in WRRO
- Mutations on the surface of HDAC1 reveal molecular determinants of specific complex assembly and their requirement for gene regulation. Nucleic Acids Research, 53(17). View this article in WRRO
- Electrospun Fibers of Polyhydroxyalkanoate/Bacterial Cellulose Blends and Their Role in Nerve Tissue Engineering. Macromolecular Materials and Engineering, 310(9).
- Mechanisms of breast cancer dormancy in bone metastasis. Clinical & Experimental Metastasis, 43(3).
- Atmospheric-Pressure Plasma Jet Interacting with Saline and Non-saline Medium: Plasma Characteristics & Liquid-Phase Chemistry. Journal of Physics D: Applied Physics.
- Refining Prognosis in Advanced Renal Cell Carcinoma: International Real-World Validation of the Meet-URO Score in First-Line Immunotherapy Combinations. The Oncologist.
- Heat Shock Proteins as Cancer Biomarkers: From Mechanism to Clinical Application. Molecular Diagnosis & Therapy.
- Author Correction: Biallelic variants in the noncoding RNA gene RNU4-2 cause a recessive neurodevelopmental syndrome with distinct white matter changes. Nature Genetics.
- A detailed methodology for developing and applying a 3D polyHIPE scaffold to model myeloma cell dormancy in vitro. F1000Research, 15, 733-733.
- Osteoporosis knowledge, health beliefs, and self-efficacy in UK men with prostate cancer: a cross-sectional primary care survey. British Journal of General Practice, 76(suppl 1), bjgp26X744969-bjgp26X744969.
- ESR1 fusion proteins in breast cancer: distinguishing oncogenic drivers from passenger events. Oncogene.
- Ex vivo drug screening and clustering of bladder cancers for pre-clinical treatment prediction. Communications Medicine.
- A multimodal explainable ai framework to assist in the differential diagnosis of head and neck reactive follicular hyperplasia and follicular lymphoma: an international multicentre study. Virchows Archiv.
- Innovations in biomarker stratification for precision oncology. Clinical and Experimental Medicine.
- ‘
BJUI
Clinical Dilemma’: Recurrent high‐grade non‐muscle‐invasive bladder cancer in 2026. BJU International.
- Generation of biologically responsive colon-like intestinal tissue patches from human induced pluripotent stem cells using a rapid co-differentiation platform. Stem Cell Research & Therapy.
- Exercise Boosts the Immune System and Enhances Immunotherapy Responses in Pancreatic Cancer and Mesothelioma. Biomolecules, 16(4), 493-493.
- TNF-α/PAD4 axis drives hyperhomocysteine-induced white matter injury after acute ischemic stroke. Acta Pharmacologica Sinica.
- Decreased Chronic
GvHD With Post‐Transplant Cyclophosphamide VersusATG in Patients With Myelofibrosis Allografted With an Unrelated Donor: A Study From the Chronic Malignancies Working Party of theEBMT . American Journal of Hematology.
- Mapping Epidermal Growth Factor Receptor-1 Sorting Domains in Endosomes with a Calibrated Three-Dimensional Expansion Microscopy Toolkit. ACS Nano.
- Tissue Damage in Rheumatoid Arthritis is Genetically linked to Low Peptidylglycine Alpha‐Amidating Monooxygenase Activity in Synovial Fibroblasts. Arthritis & Rheumatology.
- Anti-thymocyte globulin (ATG)- or alemtuzumab-based graft-versus-host disease prophylaxis in reduced-intensity conditioning allogeneic hematopoietic cell transplantation (HCT) for patients 40 years and older with acute lymphoblastic leukemia in first complete remission: a study from the EBMT Acute Leukemia Working Party. Bone Marrow Transplantation.
- Reclassification of variants of uncertain significance in type I collagen genes: a national reference laboratory experience. Journal of Medical Genetics.
- Mutational insights and in silico characterization of NEK family kinases in OSCC patients from the Pakistani population. Frontiers in Bioinformatics, 5.
- Nervous System-on-Chip: Innovative Microfluidic Platform to Compartmentalize hiPSC-Derived Neural Networks. Micromachines, 17(2), 199-199.
- Spatially resolved single-cell analysis of transcriptomic changes linked with neuropathic pain in human neuromas. Pain. View this article in WRRO
- How do clinician and parent-reported data differ? An analysis of similarity and difference in the datasets from a cross-syndrome genetics cohort study (GenROC). Journal of Medical Genetics.
- Interruption of cross-communication pathways alters the immune cell signature of pancreatic cancer and decreases tumor growth. Cell Communication and Signaling, 24(1).
- Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England. Frontline Gastroenterology.
- Resolving consecutive excited-state evolution in Fe-amido chromophores by wide-band optical transient absorption spectroscopy. Chemical Science.
- Combined electrospun fibre-microneedle patches for enhanced transmucosal delivery of benzodiazepines and proteins. Biomaterials Science.
- Independent Multicentre Validation of the ‘Six‐Point’ Model for Malignant Transformation Risk in Oral Epithelial Dysplasia. Oral Diseases.
- Are H&E-based computational models transforming molecular pathology diagnostics in cancer?. Academia Oncology, 2(4).
- Twelve-Month Results From the CISTO Study Comparing Radical Cystectomy Versus Bladder-Sparing Therapy for Recurrent High-Grade Non–Muscle-Invasive Bladder Cancer. Journal of Clinical Oncology.
- Downregulation of the CCK-B Receptor in Pancreatic Stellate Cells Blocks Molecular Proliferative Pathways and Increases Apoptosis to Decrease Pancreatic Cancer Growth In Vitro. International Journal of Molecular Sciences, 26(23), 11699-11699.
- Typhoid toxin of Salmonella Typhi elicits host antimicrobial response during acute typhoid fever. EMBO Molecular Medicine.
- Effect of a Peripheral Substituent on the Ultrafast Dynamics and the rate of Intersystem Crossing in charge-transfer states of Platinum(II) acetylides. Physical Chemistry Chemical Physics.
- Position statement from the British Society of Blood and Marrow Transplantation and Cellular Therapy on insertional oncogenesis in gene‐engineered advanced cell therapy products for treatment of haematological disorders. British Journal of Haematology.
- Neglected tropical diseases (NTDs) and related infections in hematopoietic cellular therapy (HCT) in adults and children: a survey from the Infectious Diseases Working Party (IDWP) of the European Society of Blood and Marrow Transplantation (EBMT). Bone Marrow Transplantation.
- DPSCs-Exos promote OPCs differentiation and white matter repair via Myl9-mediated PRMT5 nucleation after ischemic stroke. Journal of Cerebral Blood Flow & Metabolism.
- The role of circulating tumor DNA as a prognostic biomarker in plasma of patients with oral squamous cell carcinoma. Odontology.
- Targeting angiogenesis and white matter repair for enhanced functional recovery after acute ischemic stroke: A focus on the roles of glial cells. Journal of Cerebral Blood Flow & Metabolism.
- Cancer-Associated Fibroblasts Move and Interact More with Triple-Negative Breast Cancer Cells and Stimulate Their Proliferation in a Hyaluronan-Dependent Manner. Cells, 14(21), 1663-1663.
- Familial NSD1 Exon 3 Deletion Associated with Phenotypic and Epigenetic Variability. Genes, 16(10), 1190-1190.
- Surgical familiarity: many questions but the benefits are clear. BJU International.
Book chapters
- The Role of Artificial Intelligence to Aid Early Detection of Oral Cancer, Technology in Head & Neck Surgery (pp. 12-24). CRC Press
- Extracellular ATP and the bone, ATP (pp. 521-543). Elsevier
Conference proceedings
- Extended multi-centre review of adjuvant pembrolizumab for renal cell carcinoma.. Journal of Clinical Oncology, Vol. 44(7_suppl) (pp 458-458)
- 37 What does the neurologist need to know about thrombotic thrombocytopenic purpura?. 37 What does the neurologist need to know about thrombotic thrombocytopenic purpura? (pp A12.1-A12)
- LATE EFFECTS IN MULTIPLE MYELOMA: A SINGLE-CENTRE FOCUSED CLINIC EXPERIENCE. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 786-787)
- PATIENT REPORTED OUTCOMES IN AUTOLOGOUS ARANSPLANT IN MULTIPLE MYELOMA PATIENTS, PROSMM. SINGLE CENTRE PILOT STUDY. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 780-781)
- LONG-TERM OUTCOMES AND LATE COMPLICATIONS OF ALLOGENEIC STEM CELL TRANSPLANTATION WITH T-CELL DEPLETION: EX VIVO (CD34+POSITIVE SELECTION) VS IN VIVO (ALEMTUZUMAB-BASED CONDITIONING). BONE MARROW TRANSPLANTATION, Vol. 60 (pp 156-157)
- DECREASED CHRONIC GVHD WITH PTCY COMPARED TO ATG IN PATIENTS WITH MYELOFIBROSIS ALLOGRAFTED WITH AN UNRELATED DONOR: A STUDY FROM THE CMWP OF THE EBMT. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 148-149)
- NEGLECTED TROPICAL DISEASES (NTD) AND RELATED INFECTIONS IN HAEMATOPOIETIC CELLULAR THERAPY (HCT) IN ADULTS AND CHILDREN: A SURVEY FROM THE EBMT INFECTIOUS DISEASES WORKING PARTY. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 571-572)
- LATE COMPLICATIONS AFTER AUTOLOGOUS HSCT FOR AUTOIMMUNE DISEASES: A RETROSPECTIVE SURVEY FROM THE AUTOIMMUNE DISEASES WP (ADWP) AND TRANSPLANT COMPLICATIONS WP (TCWP) OF THE EBMT. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 16-16)
- Genotype-phenotype correlation and familial inheritance of ASXL3-related disorder. EUROPEAN JOURNAL OF HUMAN GENETICS, Vol. 33 (pp 751-751)
- Variant spectrum and genotype-phenotype correlations in HNRNPK-related disorder (Au-Kline-Okamoto syndrome). EUROPEAN JOURNAL OF HUMAN GENETICS, Vol. 33 (pp 837-837)
- Analysis of R-loop forming regions discovers RNU2-2P and RNU5B-1 as non-coding neurodevelopmental disorder genes. EUROPEAN JOURNAL OF HUMAN GENETICS, Vol. 33 (pp 46-46)
- Investigating the effect of missense variants in HNRNPU-related neurodevelopmental disorder. EUROPEAN JOURNAL OF HUMAN GENETICS, Vol. 33 (pp 760-760)
- Body Size and Non-Muscle Invasive Bladder Cancer Outcome: What Do the Genes Say?. GENETIC EPIDEMIOLOGY, Vol. 49(7)
- Machine Learning-Based Electrical Impedance Spectroscopy Classification for Oral Cancer. 2025 International Workshop on Impedance Spectroscopy (IWIS) (pp 2-6), 23 September 2025 - 26 September 2025.
- BEAM/ATG or cyclophosphamide/ATG as conditioning regimen in autologous haemopoietic stem cell transplantation for multiple sclerosis: a retrospective analysis of the EBMT autoimmune diseases working party. Bone Marrow Transplantation
Other
- Kidney cancer: diagnosis and management.
- Roadmap for the European Virtual Human Twin.
Preprints
- Single-nucleus multiomic atlas of ALS primary motor cortex nominates neuroprotective WDR49-expressing astrocytes, Springer Science and Business Media LLC.
- Isolation Strategy Shapes the Matrisome Landscape of Cancer-Associated Fibroblast Extracellular Vesicles, openRxiv.
- Mitochondrial activity directs nutrient uptake and patterning in human gastrula models, openRxiv.
- Dynamic modelling of human neural crest development using a bioengineered stem cell organoid system, openRxiv.
- Notch signalling governs human enteric nervous system progenitor dynamics, openRxiv.
- Estrogen prevents anti-tumor effects of Zoledronic acid in breast cancer through the NK and CD8+T cell PD-1/PD-L1 axes, Springer Science and Business Media LLC.
- Generation of human hindlimb/genital tubercle progenitors from pluripotent stem cells, openRxiv.
- DNA Damage Driven Viability Loss and Transcriptional Reprogramming in Chinese Hamster Ovary Cell Perfusion Culture, openRxiv.
- A bipartite mechanism for condensin II activation in mitosis, openRxiv.
- Bone Recovery After Treatment Study (BRATS) - A Protocol for a Prospective, Observational Study in Multiple Myeloma, openRxiv.
- Strong correlation between phantomless and inline phantom-based densitometric calibration of vertebral properties from CT scans of healthy volunteers, openRxiv.
- Binding Kinetics Oppositely Regulates type II Topoisomerase Relaxation and Decatenation Activities, openRxiv.
- Understanding the physiological behaviour of disc cells in an
in vitro
imitation of the healthy and degenerated disc niche, openRxiv.
- Myosin VI orchestrates estrogen-driven gene expression in breast cancer cells, Cold Spring Harbor Laboratory.
- Siglec-engaging immunosuppressive sialoglycans are upregulated in prostate cancer and are targetable to suppress bone metastasis, openRxiv.
- Reduced penetrance of
COL1A1/2
pathogenic variants linked with osteogenesis imperfecta: analysis of a large population cohort, Cold Spring Harbor Laboratory.
- Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England, Cold Spring Harbor Laboratory.
- Functional and molecular rescue of aganglionic colon by human enteric nervous system progenitor transplantation in Hirschsprung disease, Cold Spring Harbor Laboratory.
- Analysis of mRNA multimerisation (aggregation) using non-denaturing ion-pair reversed-phase HPLC, American Chemical Society (ACS).
- Verapamil limits inflammation by restoring VGCC-driven epithelial Ca2+ in models of cystic fibrosis, Cold Spring Harbor Laboratory.
- Mapping EGFR1 sorting domains in endosomes with a calibrated 3D expansion microscopy toolkit, Cold Spring Harbor Laboratory.
- Secondary nucleation of α-Synuclein drives Mitochondria dysfunctions and Lewy body formation in Parkinson’s Disease, Springer Science and Business Media LLC.
- An unbiased screening approach for identifying proteins with a mechanosensitive nuclear localization, Cold Spring Harbor Laboratory.
- Secondary nucleation of α-Synuclein drives Mitochondria dysfunctions and Lewy body formation in Parkinson’s Disease, Cold Spring Harbor Laboratory.