Sheffield publications in improving outcomes for cancer patients
The vision is to discover new treatments or better ways of giving current treatments, as well as develop new methodology for matching treatment to patients’ individual cancers. This theme encompasses discovery science – identifying new molecules and mechanisms; therapeutic innovation – developing novel treatments and combinations; and precision oncology – improving patient selection to optimise therapeutic response.
Publications
Journal articles
- Women in surgical oncology. European Journal of Surgical Oncology, 52(5), 111788-111788.
- Impact of gender on cancer care: a global and historic perspective. European Journal of Surgical Oncology, 52(5), 111730-111730.
- Equity impact and cost-effectiveness of a community health worker breast cancer educational programme in rural South Africa: a modelling study. BMJ Open, 16(4), e114908-e114908.
- A scoping review investigating the influence of comorbidities on the use and outcomes of biological therapies in breast cancer.. J Geriatr Oncol, 17(4), 102964.
- 459P mRNA profile to predict platin sensitivity in NSCLC: A translational analysis of the ETOP/EORTC SPLENDOUR trial. ESMO Open, 11, 106773-106773.
- Reducing tobacco supplier profits and pricing power: Modelling the impact of a tobacco price cap and tax increase on socioeconomic inequalities in England. Social Science & Medicine, 119325-119325.
- Timing of ileocolic resection for Crohn's disease: A survey of the patient perspective in the ‘biological’ era. Colorectal Disease, 28(4).
- Factors Affecting Nurses, Midwives and Allied Health Professionals' Ability to Engage With Research.. J Clin Nurs.
- Insights Into ‘Living Flat’: A Qualitative Study of Patients Who Have Mastectomy Without Reconstruction. Psycho-Oncology, 35(4).
- Exploring the effectiveness of physical health check interventions for people with severe mental illness: a systematic review of qualitative and quantitative evidence. BMC Health Services Research. View this article in WRRO
- Effectiveness of non-pharmacological interventions for fatigue in long term conditions: systematic review and network meta-analysis. BMJ Medicine, 5(1), e001746-e001746.
- An extraction pipeline for analysis of hematopoietic stem cell transplantation data.. Bone Marrow Transplant.
- Resistance to anti-PD-1 immunotherapy for stage III and IV melanoma: a global chart review study. Journal for ImmunoTherapy of Cancer, 14(3), e014564-e014564.
- The role of community pharmacies in the provision of human papillomavirus (HPV) self-testing: A range of delivery models and proof-of-concept study. Exploratory Research in Clinical and Social Pharmacy, 100729-100729.
- The SPACES feasibility trial: A co-produced physical activity intervention for people with severe mental illness. Mental Health and Physical Activity, 30, 100765-100765.
- Growth differentiation factor 15 and the risk of hip fracture in older adults. JBMR Plus, 10(4).
- Immune-adaptive pathogen variation reveals targetable mediators of gram-positive bacterial killing in macrophages.. Sci Adv, 12(9), eaea0375.
- Removal of small fibroids and polyps in patients with infertility and recurrent miscarriage: The HELP Fertility? RCT.. Health Technol Assess, 1-35.
- Variance of the Distance to the Boundary of Convex Domains in R2 and R3. Journal of Optimization Theory and Applications, 208(3).
- Expected change: a new concept for monitoring patients on oral bisphosphonates.. J Bone Miner Res.
- How did labelling provision on menus for online food delivery change after implementation of England's calorie labelling regulations?. Health & Place, 98, 103635-103635.
- Effectiveness and acceptability of interventions to improve faecal immunochemical test (FIT) return in both asymptomatic (screening) and symptomatic populations: protocol for a systematic review of qualitative and quantitative evidence. BMJ Open, 16(2). View this article in WRRO
- Beyond barriers: a qualitative evidence synthesis protocol of South Asian involvement in mental health research in high-income countries. BMJ Open, 16(2), e109567-e109567.
- Modelling the economic effects of reducing the consumption of unhealthy commodities: An inter-sectoral input-output approach.. Addiction.
- Adult survivors of sickle cell disease, transfusion-dependent beta-thalassaemia and childhood acute leukaemia in England: protocol for a mixed methods data linkage and health-related quality of life survey study. BMJ Open, 16(2), e111664-e111664.
- 3D environment favors persistent changes in cell functions and altered morphology, wrinkling, and biomechanical signature of the nucleus. Cell Reports Physical Science, 7(2), 103116-103116.
- Doxorubicin induces bone loss and modifies multiple cell populations in vivo – Implications for modelling of bone metastasis. Journal of Bone Oncology, 56, 100736-100736.
- DXA-derived three-dimensional finite element models of the femur: validation against CT-based models. Bone, 117830-117830.
- A Pilot Project to Evaluate the Benefit of Additional Support in Haematopoietic Cell Transplant (HCT) Research Data Management on Behalf of Anthony Nolan and BSBMTCT. eJHaem, 7(1).
- KG-Retailbot: A knowledge graph-based chatbot for explaining robotic scenario information in a retail setting. International Journal of Social Robotics, 18(1). View this article in WRRO
- P0635 Early surgery for ileocaecal Crohn’s disease: evidence versus reality. Journal of Crohn’s and Colitis, 20(Supplement_1).
- Response to Letter to the Editor Regarding "The relationship between treatment-related changes in total hip BMD measured after 12, 18, and 24 mo and fracture risk reduction in osteoporosis clinical trials: the FNIH-ASBMR-SABER project".. J Bone Miner Res.
- Target Trial Emulation to Incorporate Real-World Data in the Estimation of the Clinical and Cost-Effectiveness of Biologic Treatment. Medical Decision Making, 272989X251408484.
- Retraction Note: Antibodies against endogenous retroviruses promote lung cancer immunotherapy. Nature, 649(8099), 1330-1330.
- Feasibility and Implementation of INTERVAL-GAP4: A Global Randomised Controlled Trial of Intense Hybrid-supervised/Self-managed Versus Self-directed Exercise for Metastatic Prostate Cancer. European Urology Open Science, 84, 29-39.
- Reducing the exceptional affordability of hand-rolling tobacco using tax escalators: a health and economic impact modelling study for England. Tobacco Control. View this article in WRRO
- Protocol to identify mechanosensitive nuclear proteins using tunable actomyosin contractility and proximity biotinylation in mammalian cells. STAR Protocols, 7(1), 104288-104288.
- Second victim syndrome in surgeons: systematic review and meta-analysis of the impact of adverse events on surgeons. British Journal of Surgery, 113(1).
- Barriers and facilitators to prostate cancer healthcare in Black men in the UK: from diagnosis to survivorship. Journal of Cancer Survivorship. View this article in WRRO
- Re: Rebecca Voelker. What Is Prostate Cancer? JAMA. In press. https://doi.org/10.1001/jama.2025.10177. European Urology.
- Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study. European Urology Focus.
- RESECT: A Randomised Controlled Trial of Audit and Feedback in Non–muscle-invasive Bladder Cancer Surgery. European Urology.
- Exciting Times in Urological Oncology: Rapid Advances and Greater Complexity Are Changing Practice and Improving Outcomes. European Urology Focus.
- The importance of highlighting effective practice. Nursing Management, 32(6), 15-15.
- Nanoparticle platforms for encapsulation of therapeutic deep eutectic systems to target colorectal cancer cells. Journal of Drug Delivery Science and Technology, 114, 107517-107517.
- Efficacité, sécurité et immunogénicité du dénosumab biosimilaire GP2411 comparé au dénosumab de référence chez des femmes ménopausées atteintes d’ostéoporose à 78 semaines : étude ROSALIA, randomisée en double aveugle. Revue du Rhumatisme, 92, A68-A69.
- CO126 Gene Expression Profiling Tests to Guide Adjuvant Chemotherapy Decisions in Lymph Node-Positive Early Breast Cancer: A Systematic Review. Value in Health, 28(12), S67-S67.
- SA37 Effectiveness of Psychosocial Interventions for Adults With Substance Use Disorder and Co-Occurring Mental Health Disorder: An Umbrella Review. Value in Health, 28(12), S651-S651.
- HTA335 The Use of Real-World Evidence in Health Technology Assessment and the Application of the NICE RWE Framework: A Review of NICE Technology Appraisals. Value in Health, 28(12), S471-S472.
- EE383 Economic Evaluation of Second-Generation Colon Capsule Endoscopy for Investigation of the Colon Through Direct Visualization. Value in Health, 28(12), S180-S181.
- MSR68 Demonstrating the Importance of Modeling Rapid Cancer Progression in Screening Evaluations. Value in Health, 28(12), S506-S506.
- The Lucerne Toolbox 3: digital health and artificial intelligence to optimise the patient journey in early breast cancer—a multidisciplinary consensus. The Lancet Oncology, 26(12), e694-e706.
- Quantitative analysis of p21 expression and its prognostic associations in breast cancer epithelium. European Journal of Surgical Oncology, 51, 110748-110748.
- Prognostic value of senescence-associated markers in breast cancer: a systematic review. European Journal of Surgical Oncology, 51, 110727-110727.
- What makes a ‘good’ mastectomy? – A national qualitative study of Health Care Professionals opinions on mastectomy without reconstruction.. European Journal of Surgical Oncology, 111333-111333.
- Cost-effectiveness of procalcitonin-guided antibiotic duration for hospitalized patients with sepsis. Critical Care, 29(1), 508.
- Evidence-biased medicine? Applying a health equity lens to Sackett's methodological framework. British Journal of General Practice, 75(761), 574-578. View this article in WRRO
- Ras signalling at the actin cortex: Coordinating local and global changes to cell morphology. Current Opinion in Cell Biology, 97, 102600-102600.
- Advancing Cancer Vaccines: The UK’s Strategic Approach to Research and Innovation. British Journal of Hospital Medicine, 86(11), 1-6.
- Cost-effectiveness of risk-stratified blood-test monitoring strategies for adults with inflammatory conditions. Rheumatology, keaf623.
- Immune-based risk score derived from bulk and single-cell transcriptomics enhances prognostic stratification in MDS. Blood, 146(Supplement 1), 115-115.
- Inflammatory and metabolic gene signatures predict overall survival and response to venetoclax-based therapy in TP53 mutant AML. Blood, 146(Supplement 1), 1734-1734.
- Team familiarity: Renal, bladder and p;rostate cancer surgery outcomes with respect to team composition. European Urology Open Science, 81, S346-S346.
- Health-related quality of life in muscle invasive bladder cancer patients receiving radical surgery versus those who do not: A real-world survey. European Urology Open Science, 81, S413-S414.
- Non–muscle-invasive Bladder Cancer: Many New Options, If You Can Afford Them. European Urology.
- Wastewater-based epidemiology for local tobacco and nicotine use with small-area estimations. European journal of public health, 35(Suppl 4).
- Electronic patient-reported adverse event monitoring in academic early-phase clinical trials: A feasibility study.. Clin Trials, 17407745251378668.
- Application of the socio-ecological model to understand the drivers of excessive alcohol and salt consumption: a qualitative study in Ghana. BMJ Open, 15(10), e100490-e100490.
- Oncogenic Ras activation in permissive somatic cells triggers rapid-onset phenotypic plasticity and elicits a tumor-promoting neutrophil response. Cell Reports, 44(11), 116478-116478.
- SUN-744 Family mapping of previously identified patients with pathogenic or likely pathogenic ALPL variants using predictive genotyping and detailed phenotyping approach: the FAME case-control study. Journal of the Endocrine Society, 9(Supplement_1). View this article in WRRO
- SAT-779 Monte Carlo Resampling Validates Use of Bone Mineral Density as Surrogate to Replace Fracture in Future Randomized Trials of Osteoporosis Treatments: Results From SABRE. Journal of the Endocrine Society, 9(Supplement_1).
- SAT-808 Treatment-Related Changes In Total Hip Bone Mineral Density And Fracture Risk Reduction For Trials With Active Control And Sequential Therapy: The Fnih-Asbmr-Sabre Project. Journal of the Endocrine Society, 9(Supplement_1).
- MON-790 The Use Of Microrna Ratios To Predict Fractures In Older Women: The Opus Study. Journal of the Endocrine Society, 9(Supplement_1).
- Correction: A subset of neutrophil phagosomes is characterised by pulses of Class I PI3K activity. Disease Models & Mechanisms, 18(10).
- Development of a community research link worker role to enable culturally tailored research and empower marginalised communities to participate: the IBISES model. Research Involvement and Engagement, 11. View this article in WRRO
- Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics. The FEBS Journal. View this article in WRRO
- Hysteresis-assisted shape morphing for soft continuum robots.. Sci Adv, 11(42), eadx3024.
- Cancer cell dormancy in the bone microenvironment. Current Osteoporosis Reports, 23(1). View this article in WRRO
- 36International neoadjuvant kidney cancer consortium guidelines on assessing pathological response after neoadjuvant therapy in kidney cancer. The Oncologist, 30(Supplement_2).
- Vitamin D, muscle strength and function in South Asian women aged ≥ 60 years living in the North of England: a cross-sectional observational study. European Journal of Nutrition, 64(7). View this article in WRRO
- Treatment decision-making and quality of life versus length of life preferences of older patients with early stage cancer: A systematic review. Journal of Geriatric Oncology, 16(8), 102773-102773.
- Revisiting Neoadjuvant Chemotherapy in Cisplatin-eligible Muscle-invasive Bladder Cancer. European Urology Oncology.
- Erdafitinib in Patients with High- and Intermediate-risk Non–muscle-invasive Bladder Cancer: Final Analysis of THOR-2 Study. European Urology.
- Scoping of policy impacts for regulating e-cigarettes (SPIRE): findings from a data and decision analytic model mapping project. NIHR Open Research. View this article in WRRO
- My Diabetes & Me: study protocol for a randomised controlled trial to test the clinical and cost-effectiveness of a diabetes self-management education programme for adults with intellectual disabilities.. NIHR open research, 5, 93.
- Interventions for patients with prostate cancer on active surveillance: a narrative review. BJU International. View this article in WRRO
- My Diabetes & Me: study protocol for a randomised controlled trial to test the clinical and cost-effectiveness of a diabetes self-management education programme for adults with intellectual disabilities. [version 1; peer review: awaiting peer review]. NIHR Open Research, 5. View this article in WRRO
- Purchase price of tobacco in small retailers in Great Britain: the relationships with neighbourhood deprivation and urbanicity between 2016–2021. Tobacco Control. View this article in WRRO
- How is missing data handled in cluster randomized controlled trials? A review of trials published in the NIHR Journals Library 1997–2024. Clinical Trials. View this article in WRRO
- P12.58.A ROLE OF IL-33/ST2 AXIS IN GLIOBLASTOMA DEVELOPMENT AND ITS RESPONSE TO TREATMENT. Neuro-Oncology, 27(Supplement_3), iii130-iii130.
- Harnessing Artificial Intelligence in Head and Neck Oncology Practice. Otolaryngologic Clinics of North America.
- Ward AdmiSsion of Haematuria, an Observational mUlticentre sTudy: patient-level analysis (WASHOUT). European Urology Open Science, 80, S8-S8.
- Tumour profiling tests to guide adjuvant chemotherapy decisions in lymph node-positive early breast cancer: a systematic review and economic evaluation. Health Technology Assessment, 29(49). View this article in WRRO
- Cost-effectiveness and equity impact of complex primary care interventions for disadvantaged populations. BJGP Open. View this article in WRRO
- Surgical Interventions Improve Survival in Patients with Metastatic Uveal Melanoma. Clinical Surgical Oncology, 100102-100102.
- Developing powerful PPIE partnerships in the design of an inclusive weight management service: a case study from the NewDAWN programme. Research Involvement and Engagement, 11. View this article in WRRO
- Results from a UK consensus via Delphi on practical considerations surrounding risk assessment and patient monitoring for a prompt diagnosis of severe veno‐occlusive disease (VOD) in adults post‐HSCT. eJHaem, 6(5). View this article in WRRO
- إنهاء الأسلحة النووية قبل أن تنهي حياتنا. Arabian Journal of Scientific Research-المجلة العربية للبحث العلمي, 2025(2).
- Demonstration of an intrinsic circadian rhythm in bone resorption. Scientific Reports, 15(1). View this article in WRRO
- Ending nuclear weapons, before they end us. Internal and Emergency Medicine, 20(6), 1667-1670.
- Cost-effectiveness of different HPV vaccination strategies for cervical cancer prevention in South Africa. Vaccine, 64, 127770-127770.
- Genetic susceptibility and environmental risk factors in bladder cancer: evidence from the UK biobank. Bladder Cancer, 11(3). View this article in WRRO
- Potential cost-effectiveness of childhood screening for type 1 diabetes: Examining reducing Diabetic Ketoacidosis at diagnosis and long-term outcomes to assess the justifiable cost per child screened. [version 1; peer review: awaiting peer review]. NIHR Open Research, 5. View this article in WRRO
- DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution. Nature Genetics, 57(9), 2226-2237.
- An economic analysis of BPaL for multidrug-resistant TB in South Africa and the Philippines. IJTLD OPEN, 2(9), 535-541. View this article in WRRO
- UK recommendations for chimerism testing and monitoring following allogeneic haematopoietic stem cell transplantation (HSCT): best practice consensus guidelines from the British Society for Blood and Marrow Transplant and Cellular Therapies (BSBMTCT), NHS England Genomic Laboratory Hub (GLH) Haematological Malignancies Working Group, UK Cancer Genetics Group (UKCGG) and the UK National External Quality Assessment Service for Leucocyte Immunophenotyping (UK NEQAS LI).. Br J Haematol. View this article in WRRO
- Indications for haematopoietic cell transplantation and CAR-T for haematological diseases, solid tumours and immune disorders: 2025 EBMT practice recommendations.. Bone Marrow Transplant. View this article in WRRO
- AHL-based QS signalling promotes uropathogenic Escherichia coli settlement through the de-repression of biofilm formation by SdiA. PLOS One, 20(9). View this article in WRRO
- Mesenteric excision and Kono‐S anastomosis trial (MEErKAT): A study protocol for a multicentre, 2 × 2 factorial, randomised controlled, open‐label superiority trial. Colorectal Disease, 27(9). View this article in WRRO
- Real-world effectiveness of autologous haematopoietic stem cell transplantation for multiple sclerosis in the UK. Journal of Neurology, Neurosurgery & Psychiatry. View this article in WRRO
- Renal, bladder and prostate cancer surgery outcomes with respect to team familiarity. BJU International. View this article in WRRO
- RACE AND ‘OMIC’ DATA IN GLIOMA: A SYSTEMATIC REVIEW OF CONTEMPORARY RESEARCH TO EXPLORE THE DIGITAL DIVIDE. Neuro-Oncology, 27(Supplement_2), ii29-ii29.
- Using agent-based models to explore dietary policy mechanisms. Appetite, 213, 108071-108071.
- 1700eTiP SCOPE phase II clinical trial program evaluating off-the-shelf DNA plasmid vaccines, SCIB1 and iSCIB1+ administered in combination with checkpoint inhibitors in advanced unresectable melanoma. Annals of Oncology, 36, S1001-S1002.
- 1023eTiP Two-part, first-in-human study on Novel Pan-TEAD inhibitor ODM-212 in subjects with selected advanced solid tumours (TEADES). Annals of Oncology, 36, S665-S665.
- 144P Beyond markers: Functional assays and transcriptomics reveal CSC populations in soft tissue sarcomas. ESMO Open, 10, 105721-105721.
- 3069MO Health-related quality of life (HRQoL) outcomes from the NIAGARA trial of perioperative durvalumab (D) plus neoadjuvant chemotherapy (NAC) in muscle-invasive bladder cancer (MIBC). Annals of Oncology, 36, S1588-S1588.
- Quantitative faecal immunochemical tests to guide colorectal cancer pathway referral in primary care. A systematic review, meta-analysis and cost-effectiveness analysis. Health Technology Assessment, 29(46). View this article in WRRO
- LBA111 Randomized comparison of upfront magnetic resonance imaging versus transurethral resection for staging new bladder cancers: Final survival analysis from the BladderPath trial. Annals of Oncology, 36, S1767-S1767.
- Self‐Assessment Organisational Readiness Tool (SORT) for nursing research capacity development: results of a UK Delphi study. International Nursing Review, 72(3). View this article in WRRO
- 1046P Outcome of UK germ cell patients treated with high dose chemotherapy: A 20-year review of the BSBMTCT registry. Annals of Oncology, 36, S705-S705.
- The immunotherapy landscape in AML: Defining knowledge gaps toward rational combinatorial strategies. Seminars in Hematology, 62(3), 209-217. View this article in WRRO
- SP9.04 ‘Early’ surgery for ileocaecal Crohn’s disease: a study of the patient perspective. British Journal of Surgery, 112(Supplement_13).
- Definition of relapse criteria in patients with rapidly progressive systemic sclerosis treated with autologous haemopoietic stem cell transplantation.. Bone Marrow Transplant, 1-4. View this article in WRRO
- Testing a New Diabetes Adaptive Weight management Network (NewDAWN): A protocol for a randomised controlled trial. Contemporary Clinical Trials, 157, 108050-108050.
- Autologous haematopoietic stem cell transplantation for rheumatic diseases: best practice recommendations from the EBMT practice harmonization and guidelines committee. Bone Marrow Transplantation. View this article in WRRO
- Annotating datasets in behavioural and social sciences to promote interoperability: development of the schema for ontology-based dataset annotation (SODA) version 1.0. Wellcome Open Research, 10, 455-455. View this article in WRRO
- Microultrasonography-Guided vs MRI-Guided Biopsy for Prostate Cancer Diagnosis. JAMA, 334(7), 641-641.
- Ward AdmiSsion of Haematuria: an Observational mUlticentre sTudy (WASHOUT) – study protocol. BMJ Open, 15(8). View this article in WRRO
- Corrigendum to “The Totality of Evidence for SDZ-deno: A Biosimilar to Reference Denosumab” [Clin Ther. 2024;46:916-926]. Clinical Therapeutics, 47(10), 954-955.
- Paired and solitary ionocytes in the zebrafish olfactory epithelium. Chemical Senses, 50. View this article in WRRO
- Pectin extraction from citrus waste: structural quality and yield with mineral and organic acids. Physchem, 5(3). View this article in WRRO
- A meta-ethnography of women’s intimate and sexual experiences across the menopause continuum. International Journal of Women's Health, 17, 2465-2491. View this article in WRRO
- Determining the importance of the stringent response for methicillin-resistant staphylococcus aureus virulence in vivo. The Journal of Infectious Diseases. View this article in WRRO
- Advancing the integration of ‘basic/fundamental’ and translational cellular and gene therapy science within the EBMT: Accelerating the pathway to progress. Bone Marrow Transplantation. View this article in WRRO
- Saudi women's experiences of sexual and relational changes during the menopause transition. Journal of Advanced Nursing. View this article in WRRO
- Assessment of vault particles in cancer cell line‐derived extracellular vesicle preparations. Journal of Extracellular Vesicles, 14(8). View this article in WRRO
- ATM inhibition increases the anti-tumor efficacy of radium-223 (Ra-223) against prostate cancer bone metastasis in preclinical models. JBMR Plus, 9(10). View this article in WRRO
- Haematopoietic stem cell transplant versus immune-reconstitution therapy in relapsing multiple sclerosis. Brain. View this article in WRRO
- Modeling the impact of multicancer early detection tests: a review of natural history of disease models. Medical Decision Making, 45(8), 1013-1024. View this article in WRRO
- Uveal melanoma UK national guidelines: 2023 update. European Journal of Cancer, 228. View this article in WRRO
- Corrigendum to “Mental health burden for NHS healthcare staff during the COVID-19 pandemic: First results of a longitudinal survey” [Heliyon Volume 9, Issue 3, March 2023, Article e13765]. Heliyon, 11(13), e43296-e43296.
- The impact of age on survival and excess mortality after autologous hematopoietic cell transplantation in newly diagnosed multiple myeloma patients. Haematologica. View this article in WRRO
- Loss of Cathepsin Z enhances pro-inflammatory macrophage responses and promotes tissue regeneration in zebrafish. Disease Models & Mechanisms.
- Health-related Quality of Life in People with Autosomal Dominant Polycystic Kidney Disease: A Systematic Review. Clinical Kidney Journal.
- Lung Cancer Screening in a Population from Northeast Italy Exposed to Both Asbestos and Smoking: A Cost-Effectiveness Analysis. Journal of Clinical Medicine, 15(8), 3136-3136.
- ‘Surgery is a last resort measure’: a qualitative study of patient views on treatment for ileocaecal Crohn’s disease. Frontline Gastroenterology.
- Efficacy, pharmacodynamics, pharmacokinetics, safety, and immunogenicity of Bmab 1000 versus reference denosumab: 78-wk results from a randomized, double-blind, multicenter, parallel-arm phase 3 trial (DEVOTE) in women with postmenopausal osteoporosis. JBMR Plus.
- Generation of biologically responsive colon-like intestinal tissue patches from human induced pluripotent stem cells using a rapid co-differentiation platform. Stem Cell Research & Therapy.
- Monte Carlo Resampling Validates Use of Bone Mineral Density Change as Surrogate to Replace Fracture in Future Randomized Trials of Osteoporosis Treatments: Results From SABER. Journal of Bone and Mineral Research.
- Evaluating Digital Twin Visualizations for Safety and Trust in Robot-Assisted Dressing. ACM Transactions on Human-Robot Interaction.
- Improvement of Bone Mineral Density in Patients with Type 1 Gaucher Disease Treated with Velaglucerase Alfa: Results from Clinical Studies. Journal of Clinical Medicine, 15(7), 2537-2537.
- Exercise Boosts the Immune System and Enhances Immunotherapy Responses in Pancreatic Cancer and Mesothelioma. Biomolecules, 16(4), 493-493.
- Decreased Chronic
GvHD With Post‐Transplant Cyclophosphamide VersusATG in Patients With Myelofibrosis Allografted With an Unrelated Donor: A Study From the Chronic Malignancies Working Party of theEBMT . American Journal of Hematology.
- Sample size calculations for pilot cluster-randomised controlled trial: a review 2010–2020. Pilot and Feasibility Studies.
- Acceptability of, and preference for, HPV self-sampling for physically Disabled women: a cross-sectional survey. Journal of Medical Screening.
- Tissue Damage in Rheumatoid Arthritis is Genetically linked to Low Peptidylglycine Alpha‐Amidating Monooxygenase Activity in Synovial Fibroblasts. Arthritis & Rheumatology.
- Anti-thymocyte globulin (ATG)- or alemtuzumab-based graft-versus-host disease prophylaxis in reduced-intensity conditioning allogeneic hematopoietic cell transplantation (HCT) for patients 40 years and older with acute lymphoblastic leukemia in first complete remission: a study from the EBMT Acute Leukemia Working Party. Bone Marrow Transplantation.
- Ten Recommendations for Modelling Cost Effectiveness of Screening: Perspectives of an International Stakeholder Group. PharmacoEconomics.
- Clinician and patient experiences with opportunistic offer of HPV self-testing in Aotearoa New Zealand primary care clinics: interview and survey findings. BMC Primary Care.
- Bone turnover markers in the management of CKD-associated osteoporosis – a European consensus. Nephrology Dialysis Transplantation.
- Precision nutrition must consider cost-effectiveness to deliver benefits to patients. Nature Medicine.
- Bracing AdoleScent Idiopathic Scoliosis after skeletal maturity (BASIS 2): study protocol for a randomized controlled trial within a larger trial. Bone & Joint Open, 7(1), 130-137.
- Online information on bowel resection for Crohn’s disease. The Annals of The Royal College of Surgeons of England.
- Public health impacts of increasing the minimum unit price for alcohol in Scotland: A model-based appraisal. PLOS Medicine, 23(1), e1004792-e1004792.
- Independent Multicentre Validation of the ‘Six‐Point’ Model for Malignant Transformation Risk in Oral Epithelial Dysplasia. Oral Diseases.
- Anti-Mullerian Hormone and Collagen Type I C-telopeptide Predict Fast, Imminent Bone Loss in Early Perimenopause: SWAN. The Journal of Clinical Endocrinology & Metabolism.
- Twelve-Month Results From the CISTO Study Comparing Radical Cystectomy Versus Bladder-Sparing Therapy for Recurrent High-Grade Non–Muscle-Invasive Bladder Cancer. Journal of Clinical Oncology.
- Design, synthesis and biological activity of glycoconjugated ADAMTS5 exosite inhibitors: applications in osteoarthritis and ovarian cancer models. Scientific Reports.
- The PRAMS (Perinatal Redesign for Accessing Mental Health Services) Study: a research protocol. BJGP Open, BJGPO.2025.0206-BJGPO.2025.0206.
- Ten tips on performing economic evaluation in kidney disease. Clinical Kidney Journal.
- Multiplicity adjustment approaches in publicly funded multi-arm trials: a comprehensive review of the National Institute for Health and Care Research (NIHR) Journals Library. Trials.
- Effect of Childhood Exposure to Domestic Violence and Abuse on Adult Relationships: A Mental Health Nurse Perspective. Journal of Psychosocial Nursing and Mental Health Services, 1-8.
- Opportunistic offer of human papillomavirus (HPV) self-testing in ethnically diverse primary care clinics in Aotearoa New Zealand: an implementation study. BMC Primary Care.
- Development, Validation and Effectiveness of Postnatal Care Module for Confinement Ladies: A concept paper. Environment-Behaviour Proceedings Journal, 10(SI35), 177-183.
- A Consensus Statement on the management of Vertebral Fractures in CKD stages G4-G5D. Nephrology Dialysis Transplantation.
- The DIAMONDS intervention for type 2 diabetes for people with severe mental illness: findings from a single-group feasibility study. Frontiers in Health Services, 5.
- Position statement from the British Society of Blood and Marrow Transplantation and Cellular Therapy on insertional oncogenesis in gene‐engineered advanced cell therapy products for treatment of haematological disorders. British Journal of Haematology.
- Neglected tropical diseases (NTDs) and related infections in hematopoietic cellular therapy (HCT) in adults and children: a survey from the Infectious Diseases Working Party (IDWP) of the European Society of Blood and Marrow Transplantation (EBMT). Bone Marrow Transplantation.
- The UK Vaccine Innovation Pathway. Immunotherapy Advances.
- Methotrexate oral or subcutaneous for rheumatoid arthritis (MOOSE): study protocol for a multi-centre randomised trial. Trials, 26(1).
- Turning the Tide: Harnessing Vaccines and Viruses to Fight Cancer. Immunotherapy Advances.
- Randomized controlled trial of an oral Gastrin Receptor Antagonist for the treatment of postmenopausal osteoporosis. Journal of Bone and Mineral Research.
- Religious and cultural influences on domestic violence attitudes and responses in UK ethnic minority and migrant communities: A qualitative inquiry. Violence: An International Journal.
- Understanding mechanisms of colorectal cancer chemoprevention using seAFOod polyp prevention trial outcomes and its Biobank: STOP-ADENOMA synopsis. Efficacy and Mechanism Evaluation, 1-20.
- Using inverse probability of censoring weighting to estimate hypothetical estimands in clinical trials: Should we implement stabilisation, and if so how?. Statistical Methods in Medical Research.
- A core outcome set for locoregional treatment reporting in neoadjuvant systemic breast cancer treatment trials. npj Breast Cancer, 11(1).
- Cancer-Associated Fibroblasts Move and Interact More with Triple-Negative Breast Cancer Cells and Stimulate Their Proliferation in a Hyaluronan-Dependent Manner. Cells, 14(21), 1663-1663.
- Surgical familiarity: many questions but the benefits are clear. BJU International.
- Integrating Intersectionality Theory for Informing Health Policymaking. World Medical & Health Policy.
- Augmented two-stage estimation for treatment switching in oncology trials: Leveraging external data for improved precision. Statistical Methods in Medical Research.
- Acute effect of impact and resistance exercise on Wnt signaling modulators, bone and cartilage metabolism. Journal of Bone and Mineral Research.
- Preanalytical variables and analytes in liquid biopsy approach for brain tumors: A comprehensive review and recommendations from the RANO Group and the Brain Liquid Biopsy Consortium. Neuro-Oncology.
- Ending Nuclear Weapons, Before They End Us. The National Medical Journal of India, 38, 129-132.
Book chapters
- Marker density of optical tactile sensor for moving object tracking In Cavalcanti A, Foster S & Richardson R (Ed.), Towards Autonomous Robotic Systems (pp. 54-67). Springer Nature Switzerland View this article in WRRO
- Educational and training harmonization in breast cancer In Verhoeven D, Kaufman CS, Roy PG & Siesling S (Ed.), Breast Cancer (pp. 79-92). Oxford University PressOxford
- Qualitative evidence synthesis In Facey KM, Holtorf A-P & Single ANV (Ed.), Patient Involvement in Health Technology Assessment (pp. 177-194). Springer Nature Switzerland View this article in WRRO
- Extracellular ATP and the bone, ATP (pp. 521-543). Elsevier
- Development of the semicircular canals and otolithic organs of the vertebrate inner ear In Richardson GP & Wu DK (Ed.), Development of Sensory Organs (pp. 125-184). Elsevier View this article in WRRO
- Shared decision making in breast cancer surgery In Elwyn G, Joseph-Williams N & Edwards A (Ed.), Oxford Textbook of Shared Decision Making in Healthcare (pp. 192-198). Oxford University PressOxford
Conference proceedings
- Extended multi-centre review of adjuvant pembrolizumab for renal cell carcinoma.. Journal of Clinical Oncology, Vol. 44(7_suppl) (pp 458-458)
- Symbolic Runtime Verification and Adaptive Decision-Making for Robot-Assisted Dressing (pp 290-308)
- SA90 Systematic Review of Doubly Robust Methods for Population-Adjusted Indirect Comparisons. Value in Health, Vol. 28(12) (pp S663-S664)
- MSR214 Using Directed Acyclic Graphs in Matching-Adjusted Indirect Comparison and Simulated Treatment Comparison: Systematic Review and Methodological Insights. Value in Health, Vol. 28(12) (pp S537-S538)
- EFFECTIVENESS OF PSYCHOSOCIAL INTERVENTIONS FOR ADULTS WITH SUBSTANCE USE DISORDER AND CO-OCCURRING MENTAL HEALTH DISORDER: AN UMBRELLA REVIEW. VALUE IN HEALTH, Vol. 28(12)
- USING DIRECTED ACYCLIC GRAPHS IN MATCHING-ADJUSTED INDIRECT COMPARISON AND SIMULATED TREATMENT COMPARISON: SYSTEMATIC REVIEW AND METHODOLOGICAL INSIGHTS. VALUE IN HEALTH, Vol. 28(12)
- ECONOMIC EVALUATION OF SECOND-GENERATION COLON CAPSULE ENDOSCOPY FOR INVESTIGATION OF THE COLON THROUGH DIRECT VISUALIZATION. VALUE IN HEALTH, Vol. 28(12)
- THE USE OF REAL-WORLD EVIDENCE IN HEALTH TECHNOLOGY ASSESSMENT AND THE APPLICATION THE NICE RWE FRAMEWORK: A REVIEW OF NICE TECHNOLOGY APPRAISALS. VALUE IN HEALTH, Vol. 28(12)
- GENE EXPRESSION PROFILING TESTS TO GUIDE ADJUVANT CHEMOTHERAPY DECISIONS IN LYMPH NODE-POSITIVE EARLY BREAST CANCER: A SYSTEMATIC REVIEW. VALUE IN HEALTH, Vol. 28(12)
- DEMONSTRATING THE IMPORTANCE OF MODELING RAPID CANCER PROGRESSION IN SCREENING EVALUATIONS. VALUE IN HEALTH, Vol. 28(12)
- SYSTEMATIC REVIEW OF DOUBLY ROBUST METHODS FOR POPULATION-ADJUSTED INDIRECT COMPARISONS. VALUE IN HEALTH, Vol. 28(12)
- 37 What does the neurologist need to know about thrombotic thrombocytopenic purpura?. 37 What does the neurologist need to know about thrombotic thrombocytopenic purpura? (pp A12.1-A12)
- (ID: 231) ‘Mystery shopper’ blood pressure checks in pharmacies: the patient experience. International Journal of Pharmacy Practice, Vol. 33(Supplement_1) (pp i63-i63)
- LATE EFFECTS IN MULTIPLE MYELOMA: A SINGLE-CENTRE FOCUSED CLINIC EXPERIENCE. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 786-787)
- PATIENT REPORTED OUTCOMES IN AUTOLOGOUS ARANSPLANT IN MULTIPLE MYELOMA PATIENTS, PROSMM. SINGLE CENTRE PILOT STUDY. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 780-781)
- LONG-TERM OUTCOMES AND LATE COMPLICATIONS OF ALLOGENEIC STEM CELL TRANSPLANTATION WITH T-CELL DEPLETION: EX VIVO (CD34+POSITIVE SELECTION) VS IN VIVO (ALEMTUZUMAB-BASED CONDITIONING). BONE MARROW TRANSPLANTATION, Vol. 60 (pp 156-157)
- DECREASED CHRONIC GVHD WITH PTCY COMPARED TO ATG IN PATIENTS WITH MYELOFIBROSIS ALLOGRAFTED WITH AN UNRELATED DONOR: A STUDY FROM THE CMWP OF THE EBMT. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 148-149)
- NEGLECTED TROPICAL DISEASES (NTD) AND RELATED INFECTIONS IN HAEMATOPOIETIC CELLULAR THERAPY (HCT) IN ADULTS AND CHILDREN: A SURVEY FROM THE EBMT INFECTIOUS DISEASES WORKING PARTY. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 571-572)
- LATE COMPLICATIONS AFTER AUTOLOGOUS HSCT FOR AUTOIMMUNE DISEASES: A RETROSPECTIVE SURVEY FROM THE AUTOIMMUNE DISEASES WP (ADWP) AND TRANSPLANT COMPLICATIONS WP (TCWP) OF THE EBMT. BONE MARROW TRANSPLANTATION, Vol. 60 (pp 16-16)
- 1325 SCOPE, an open label phase 2 parallel multi cohort clinical trial evaluating an off-the-shelf DNA plasmid vaccine in first line advanced melanoma combined with checkpoint blockade – interim read-out. Late-Breaking Abstracts (pp A1564-A1565)
- 609 Restoring immune responsiveness in periphery and tumor with mRNA-4359, an mRNA-based therapy encoding PD-L1 and IDO1 peptides, plus pembrolizumab in checkpoint inhibitor resistant/refractory melanoma. Regular and Young Investigator Award Abstracts (pp A694-A694)
- Mailed At-Home Human Papillomavirus (HPV) Self-Testing and Telehealth Management in Aotearoa New Zealand: An Implementation Study. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, Vol. 21
- Body Size and Non-Muscle Invasive Bladder Cancer Outcome: What Do the Genes Say?. GENETIC EPIDEMIOLOGY, Vol. 49(7)
- Robotic colonoscopy: can high fidelity simulation optimize robot design and validation?. 2025 IEEE International Conference on Robotics and Automation (ICRA) (pp 2954-2960). Atlanta, GA, USA, 19 May 2025 - 19 May 2025. View this article in WRRO
- Effectiveness of autologous haematopoietic stem cell transplant in comparison with anti-CD20 therapies in relapsing-remitting multiple sclerosis. MULTIPLE SCLEROSIS JOURNAL, Vol. 31(3) (pp 714-717)
- BEAM/ATG or cyclophosphamide/ATG as conditioning regimen in autologous haemopoietic stem cell transplantation for multiple sclerosis: a retrospective analysis of the EBMT autoimmune diseases working party. Bone Marrow Transplantation
Preprints
- Estrogen prevents anti-tumor effects of Zoledronic acid in breast cancer through the NK and CD8+T cell PD-1/PD-L1 axes, Springer Science and Business Media LLC.
- Oncogenic RAS-driven α2 integrin induction under nutrient stress promotes cancer cell motility, openRxiv.
- During an inflammatory response, zebrafish tnfa and tnfb are expressed by different cell types and have distinct expression kinetics, eLife Sciences Publications, Ltd.
- During an inflammatory response, zebrafish tnfa and tnfb are expressed by different cell types and have distinct expression kinetics, eLife Sciences Publications, Ltd.
- DNA Damage Driven Viability Loss and Transcriptional Reprogramming in Chinese Hamster Ovary Cell Perfusion Culture, openRxiv.
- Metal-catalysed Hydroboration of Amide-containing Styrenes, American Chemical Society (ACS).
- Bone Recovery After Treatment Study (BRATS) - A Protocol for a Prospective, Observational Study in Multiple Myeloma, openRxiv.
- A health economic evaluation of calorie labelling in the out-of-home sector in England: A modelling study, openRxiv.
- GPU acceleration of cell-based simulations in Chaste using FLAME GPU 2, openRxiv.
- Strong correlation between phantomless and inline phantom-based densitometric calibration of vertebral properties from CT scans of healthy volunteers, openRxiv.
- Barriers and Facilitators to Prostate Cancer Healthcare in Black Men in the UK: From Diagnosis to Survivorship, Springer Science and Business Media LLC.
- Clinician and patient experiences with opportunistic offer of HPV self-testing in Aotearoa New Zealand primary care clinics: interview and survey findings, Springer Science and Business Media LLC.
- Collagen I promotes cancer cell survival via amino acid import and mTORC1 activation, Cold Spring Harbor Laboratory.
- Myosin VI orchestrates estrogen-driven gene expression in breast cancer cells, Cold Spring Harbor Laboratory.
- Siglec-engaging immunosuppressive sialoglycans are upregulated in prostate cancer and are targetable to suppress bone metastasis, openRxiv.
- During an inflammatory response, zebrafish
tnfa
and
tnfb
are expressed by different cell types and have distinct expression kinetics, Cold Spring Harbor Laboratory.
- Acceptability of, and preference for, HPV self-sampling for physically Disabled women: a cross-sectional survey, Springer Science and Business Media LLC.
- Verapamil limits inflammation by restoring VGCC-driven epithelial Ca2+ in models of cystic fibrosis, Cold Spring Harbor Laboratory.
- Beyond pulling: microtubule pushing forces contribute to robust spindle orientation in regular and irregular cell shapes, Cold Spring Harbor Laboratory.
- An unbiased screening approach for identifying proteins with a mechanosensitive nuclear localization, Cold Spring Harbor Laboratory.
- Global abuse of older people: A mega‐map of systematic reviews on prevalence, consequences, risk and protective factors and interventions, Center for Open Science.