Sheffield publications in cancer prevention and early diagnosis
The research within this theme describes and analyses the characteristics of Yorkshire populations and patients, and the cancers experienced, to help identify factors that contribute to poor outcomes. The vision is that gaining a better understanding of Yorkshire’s cancer patients, will help to develop targeted interventions and screening programmes to improve survival, primarily through earlier diagnosis.
Publications
Journal articles
- A multimodal explainable ai framework to assist in the differential diagnosis of head and neck reactive follicular hyperplasia and follicular lymphoma: an international multicentre study. Virchows Archiv. View this article in WRRO
- Thermal and chemical control of emission and excited-state dynamics in non-(TMS)3P-derived InP quantum dots.. J Chem Phys, 164(14).
- Reducing tobacco supplier profits and pricing power: Modelling the impact of a tobacco price cap and tax increase on socioeconomic inequalities in England. Social Science & Medicine, 119325-119325.
- One-Step Detection of miRNA-21 Cancer Marker in Serum using Molecularly Imprinted Nanoparticle Recognition and Surface Plasmon Resonance. Analytica Chimica Acta, 345529-345529.
- Effectiveness of non-pharmacological interventions for fatigue in long term conditions: systematic review and network meta-analysis. BMJ Medicine, 5(1), e001746-e001746.
- A Biocompatible and Flexible medium chain length PHA, P(3HB-co-20mol%3HHx) for Neural Tissue Engineering. Journal of Biotechnology.
- Innovative P(3HB)/carbon-based material composites for bone tissue regeneration: Biocompatibility, thermo-mechanical, and structural insights. Materials Today Advances, 29.
- The role of community pharmacies in the provision of human papillomavirus (HPV) self-testing: A range of delivery models and proof-of-concept study. Exploratory Research in Clinical and Social Pharmacy, 100729-100729.
- Proton-coupled electron transfer from the hydride perspective: resolving metal oxidation and protonation in a hydridocarbonyl complex by 2D-IR spectroelectrochemistry. The Journal of Physical Chemistry Letters, 17(10), 3008-3012. View this article in WRRO
- Effectiveness and acceptability of interventions to improve faecal immunochemical test (FIT) return in both asymptomatic (screening) and symptomatic populations: protocol for a systematic review of qualitative and quantitative evidence. BMJ Open, 16(2). View this article in WRRO
- British Society of Gastroenterology and Association of Coloproctology of Great Britain and Ireland position on tranexamic acid in upper and lower gastrointestinal bleeding. Colorectal Disease, 28(2).
- Modelling the economic effects of reducing the consumption of unhealthy commodities: An inter-sectoral input-output approach.. Addiction.
- Co-solute Effects Reveal the Nature of Weak Forces Governing GLP-1 Oligomers Stability. Journal of Biological Chemistry, 111223-111223.
- Reducing the exceptional affordability of hand-rolling tobacco using tax escalators: a health and economic impact modelling study for England. Tobacco Control. View this article in WRRO
- A critical comparison of polypropylene and polyurethane sling materials after implantation in a suburethral sheep model. Biomaterials, 328, 123852-123852.
- Barriers and facilitators to prostate cancer healthcare in Black men in the UK: from diagnosis to survivorship. Journal of Cancer Survivorship. View this article in WRRO
- EE383 Economic evaluation of second-generation colon capsule endoscopy for investigation of the colon through direct visualization. Value in Health, 28(12, Supplement 1), S180-S181. View this article in WRRO
- CO126 Gene Expression Profiling Tests to Guide Adjuvant Chemotherapy Decisions in Lymph Node-Positive Early Breast Cancer: A Systematic Review. Value in Health, 28(12), S67-S67.
- CO180 Pillcam COLON 2 for Investigation of the COLON Through Direct Visualization: A Systematic Review. Value in Health, 28(12), S78-S78.
- Evidence-biased medicine? Applying a health equity lens to Sackett's methodological framework. British Journal of General Practice, 75(761), 574-578. View this article in WRRO
- Smoking cessation after referral from hospital to community stop smoking services: an observational study. BMJ Public Health, 3(2), e001659-e001659.
- Faecal immunochemical test demonstrates modest decline in performance characteristics but additional prognostic roles: An evaluation in a symptomatic primary care cohort. Colorectal Disease, 27(11).
- Wastewater-based epidemiology for local tobacco and nicotine use with small-area estimations. European Journal of Public Health, 35(Supplement_4).
- Development of a community research link worker role to enable culturally tailored research and empower marginalised communities to participate: the IBISES model. Research Involvement and Engagement, 11. View this article in WRRO
- Vitamin D, muscle strength and function in South Asian women aged ≥ 60 years living in the North of England: a cross-sectional observational study. European Journal of Nutrition, 64(7). View this article in WRRO
- Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer. Nature Communications, 16(1). View this article in WRRO
- Scoping of policy impacts for regulating e-cigarettes (SPIRE): findings from a data and decision analytic model mapping project. NIHR Open Research. View this article in WRRO
- Purchase price of tobacco in small retailers in Great Britain: the relationships with neighbourhood deprivation and urbanicity between 2016–2021. Tobacco Control. View this article in WRRO
- Harnessing Artificial Intelligence in Head and Neck Oncology Practice. Otolaryngologic Clinics of North America.
- Tumour profiling tests to guide adjuvant chemotherapy decisions in lymph node-positive early breast cancer: a systematic review and economic evaluation. Health Technology Assessment, 29(49). View this article in WRRO
- Surgical Interventions Improve Survival in Patients with Metastatic Uveal Melanoma. Clinical Surgical Oncology, 100102-100102.
- Developing powerful PPIE partnerships in the design of an inclusive weight management service: a case study from the NewDAWN programme. Research Involvement and Engagement, 11. View this article in WRRO
- Cost-effectiveness of different HPV vaccination strategies for cervical cancer prevention in South Africa. Vaccine, 64, 127770-127770.
- Electrospun Fibers of Polyhydroxyalkanoate/Bacterial Cellulose Blends and Their Role in Nerve Tissue Engineering. Macromolecular Materials and Engineering, 310(9).
- An economic analysis of BPaL for multidrug-resistant TB in South Africa and the Philippines. IJTLD OPEN, 2(9), 535-541. View this article in WRRO
- 144P Beyond markers: Functional assays and transcriptomics reveal CSC populations in soft tissue sarcomas. ESMO Open, 10, 105721-105721.
- Quantitative faecal immunochemical tests to guide colorectal cancer pathway referral in primary care. A systematic review, meta-analysis and cost-effectiveness analysis. Health Technology Assessment, 29(46). View this article in WRRO
- Circular dichroism and multiphoton circularly polarized luminescence switching using a bis‐perylene diimide macrocycle. Chemistry – A European Journal. View this article in WRRO
- Annotating datasets in behavioural and social sciences to promote interoperability: development of the schema for ontology-based dataset annotation (SODA) version 1.0. Wellcome Open Research, 10, 455-455. View this article in WRRO
- Direct observation of two-channel photodissociation of carbon monoxide from the hemoglobin subunits. Nature Communications, 16(1). View this article in WRRO
- Assessment of vault particles in cancer cell line‐derived extracellular vesicle preparations. Journal of Extracellular Vesicles, 14(8). View this article in WRRO
- Uveal melanoma UK national guidelines: 2023 update. European Journal of Cancer, 228. View this article in WRRO
- Advancing synthetic bone tissue engineering materials: Nano-scale investigation into transitional Interface in carbon dots/ polymer composites. Journal of Colloid and Interface Science, 700(Part 3). View this article in WRRO
- Awakening the sense of the possible: the Symptoms Clinic as liminal affective technology. Social Science & Medicine, 383. View this article in WRRO
- Stakeholder perspectives on the barriers and facilitators to integrating cardiovascular disease and diabetes management at primary care in Kenya. PLOS Global Public Health, 5(7). View this article in WRRO
- Cost and effectiveness of differentiated ART service delivery strategies in Zambia: a modelling analysis using routine data. Journal of the International AIDS Society, 28(7). View this article in WRRO
- Model-based appraisal of the potential effects of minimum pricing for tobacco in Scotland. Tobacco Control. View this article in WRRO
- Experience-based co-design of an active case finding service for colorectal cancer in community pharmacies: findings from a focused ethnography. Research Involvement and Engagement, 11. View this article in WRRO
- Biosynthesis, characterisation and biocompatibility of a unique and elastomeric medium chain-length polyhydroxyalkanoates for kidney glomerular tissue engineering. Materials Today Bio, 33, 101932-101932.
- Targeting metastasis in paediatric bone sarcomas. Molecular Cancer, 24. View this article in WRRO
- Electrospun fibers of polyhydroxyalkanoate/bacterial cellulose blends and their role in nerve tissue engineering. Macromolecular Materials and Engineering. View this article in WRRO
- Breast cancer screening using clinical breast examination: a cost-effectiveness analysis for South Africa. Value in Health Regional Issues, 49. View this article in WRRO
- Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma. Molecular Oncology. View this article in WRRO
- A systematic review and meta-analysis of risk factors and predictors of thyroid cancer in patients with thyroid nodules. British Journal of Surgery, 112(Supplement_9).
- Osteoporosis knowledge, health beliefs, and self-efficacy in UK men with prostate cancer: a cross-sectional primary care survey. British Journal of General Practice, 76(suppl 1), bjgp26X744969-bjgp26X744969.
- Ex vivo drug screening and clustering of bladder cancers for pre-clinical treatment prediction. Communications Medicine.
- An implementation study of text invitation, mailed at-home human papillomavirus (HPV) self-testing and telehealth management in Aotearoa New Zealand, with a nested randomised controlled trial that compared offering an incentive vs. no offer with a repeat test kit. BMC Public Health.
- Early insights from a national scheme providing vaping devices for smoking cessation: A preliminary evaluation to inform future return‐on‐investment modelling in England. Addiction.
- Innovations in biomarker stratification for precision oncology. Clinical and Experimental Medicine.
- Application of Decision-Analytic Models to Evaluate Integrated Care Interventions for Cardiometabolic Multimorbidity: A Systematic Review. International Journal of Integrated Care, 26, 7-7.
- Lung Cancer Screening in a Population from Northeast Italy Exposed to Both Asbestos and Smoking: A Cost-Effectiveness Analysis. Journal of Clinical Medicine, 15(8), 3136-3136.
- Stakeholders perspectives on the barriers and facilitators for implementing integrated primary care for cardiometabolic disease prevention and management in Kenya. International Journal of Integrated Care, 26(S1), 569-569.
- Low and no alcohol availability and sales in small retailers in Great Britain: A geographic longitudinal analysis from 2018 to 2022. Addiction.
- Mapping Epidermal Growth Factor Receptor-1 Sorting Domains in Endosomes with a Calibrated Three-Dimensional Expansion Microscopy Toolkit. ACS Nano.
- Acceptability of, and preference for, HPV self-sampling for physically Disabled women: a cross-sectional survey. Journal of Medical Screening.
- Clinician and patient experiences with opportunistic offer of HPV self-testing in Aotearoa New Zealand primary care clinics: interview and survey findings. BMC Primary Care.
- Access-related factors and e-cigarette use among 11–17-year-olds: a thematic synthesis of European studies using the five dimensions of access. BMC Public Health.
- British Society of Gastroenterology and Association of Coloproctology of Great Britain and Ireland position on tranexamic acid in upper and lower gastrointestinal bleeding. Frontline Gastroenterology.
- Public health impacts of increasing the minimum unit price for alcohol in Scotland: A model-based appraisal. PLOS Medicine, 23(1), e1004792-e1004792.
- Engineering molecularly imprinted polymers for receptor-specific cancer therapeutics. Nanoscale.
- Resolving consecutive excited-state evolution in Fe-amido chromophores by wide-band optical transient absorption spectroscopy. Chemical Science.
- Independent Multicentre Validation of the ‘Six‐Point’ Model for Malignant Transformation Risk in Oral Epithelial Dysplasia. Oral Diseases.
- The PRAMS (Perinatal Redesign for Accessing Mental Health Services) Study: a research protocol. BJGP Open, BJGPO.2025.0206-BJGPO.2025.0206.
- Opportunistic offer of human papillomavirus (HPV) self-testing in ethnically diverse primary care clinics in Aotearoa New Zealand: an implementation study. BMC Primary Care.
- Effect of a Peripheral Substituent on the Ultrafast Dynamics and the rate of Intersystem Crossing in charge-transfer states of Platinum(II) acetylides. Physical Chemistry Chemical Physics.
- Understanding mechanisms of colorectal cancer chemoprevention using seAFOod polyp prevention trial outcomes and its Biobank: STOP-ADENOMA synopsis. Efficacy and Mechanism Evaluation, 1-20.
- Correction to “Electrospun Fibers of Polyhydroxyalkanoate/Bacterial Cellulose Blends and Their Role in Nerve Tissue Engineering”. Macromolecular Materials and Engineering.
- Setting a vision for British Society of Gastroenterology guidelines: embracing innovation while preserving methodological excellence and clinical utility. Gut.
Book chapters
- Qualitative evidence synthesis In Facey KM, Holtorf A-P & Single ANV (Ed.), Patient Involvement in Health Technology Assessment (pp. 177-194). Springer Nature Switzerland View this article in WRRO
- Extracellular ATP and the bone, ATP (pp. 521-543). Elsevier
Conference proceedings
- ECONOMIC EVALUATION OF SECOND-GENERATION COLON CAPSULE ENDOSCOPY FOR INVESTIGATION OF THE COLON THROUGH DIRECT VISUALIZATION. VALUE IN HEALTH, Vol. 28(12)
- GENE EXPRESSION PROFILING TESTS TO GUIDE ADJUVANT CHEMOTHERAPY DECISIONS IN LYMPH NODE-POSITIVE EARLY BREAST CANCER: A SYSTEMATIC REVIEW. VALUE IN HEALTH, Vol. 28(12)
- PILLCAM COLON 2 FOR INVESTIGATION OF THE COLON THROUGH DIRECT VISUALIZATION: A SYSTEMATIC REVIEW. VALUE IN HEALTH, Vol. 28(12)
- (ID: 231) ‘Mystery shopper’ blood pressure checks in pharmacies: the patient experience. International Journal of Pharmacy Practice, Vol. 33(Supplement_1) (pp i63-i63)
- Mailed At-Home Human Papillomavirus (HPV) Self-Testing and Telehealth Management in Aotearoa New Zealand: An Implementation Study. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, Vol. 21
- Experience-based Co-design of an Active Case Finding Service for Colorectal Cancer in Community Pharmacies: Findings From a Focused Ethnography. INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE, Vol. 32(SUPPL1) (pp 176-176)
Other
Preprints
- Bone Recovery After Treatment Study (BRATS) - A Protocol for a Prospective, Observational Study in Multiple Myeloma, openRxiv.
- Clinician and patient experiences with opportunistic offer of HPV self-testing in Aotearoa New Zealand primary care clinics: interview and survey findings, Springer Science and Business Media LLC.
- Acceptability of, and preference for, HPV self-sampling for physically Disabled women: a cross-sectional survey, Springer Science and Business Media LLC.
- Mapping EGFR1 sorting domains in endosomes with a calibrated 3D expansion microscopy toolkit, Cold Spring Harbor Laboratory.
- Effectiveness of non-pharmacological Interventions For Fatigue in Long term conditions (EIFFEL)-systematic review and network meta-analysis, Cold Spring Harbor Laboratory.