The world’s first biological computers, powered by living human brain cells, are moving from laboratories into commercial data centres. While most attention has focused on their technical potential, cities will have to decide where these facilities are built, how they are governed and whether existing planning and regulatory systems are equipped for this entirely new kind of infrastructure.
Biocomputing data centers are facilities that use human neurons cultured from stem cells as their computing substrate. These pose a challenge to urban governance that it is not equipped to meet. Because biocomputing is assembled through data centers, biomedical precincts, energy regimes, and experimental planning environments, it is both a bioethical issue and an urban problem of siting, infrastructural regulation, and public oversight. Focusing on the emergence of facilities in Melbourne and Singapore, this paper argues that urban infrastructure studies implicitly assume the material substrate to be inert. Pipes, cables, fiber, and code do not raise questions of sentience, consent, or biological sourcing. Yet biocomputing disturbs that assumption. The paper identifies a qualitative break with people-as-infrastructure, ghost work and clinical labor, each of which retains the whole person as its unit of analysis. Biocomputing incorporates fragments of the human body that are stripped to their biological minimum. This life is present in the data center to compute, yet remains absent from urban governance. Singapore’s convergence of Smart Nation ambition, Biopolis strategy, and serious energy constraints makes it a theoretically productive first case for exploring the conceptual landscape of urban infrastructure studies post-inert turn.