Assessment and prevention of bone and joint deterioration
We use multi-disciplinary approaches spanning tissue engineering, advanced imaging and multi-scale computational models to study the effect of different diseases on the biomechanical competence of the skeleton.
![Scan of a human vertebra showing local deformation](http://cdn.sheffield.ac.uk/sites/default/files/styles/mobile_single_column_1x/public/2024-07/vertebra.png.jpg?itok=7kFqtDhG)
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We aim to improve current approaches for the early diagnosis and prevention of musculoskeletal diseases.
We use our expertise in multi-scale experimental and computational biomechanics to study many research areas, including:
- Osteoarthritis, including the effects of mechanical loads, obesity or inflammation on joint function
- Back pain due to intervertebral disc degeneration or muscle weakness
- Tissue interactions and the biomechanics of the tissue interfaces
- Overload and injuries leading to the failure of soft tissues
- Fractures due to osteoporosis, sarcopenia, or overloads
- Monitoring and diagnosis, eg longitudinal imaging and modelling to monitor disease development