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  • cetuximab_final_200309

    https://sheffield.ac.uk/media/33905/download?attachment
    11. Table 5 - Manufacturers revised estimate of the cost of liver resection surgery. ... provide additional economic analyses for the use of cetuximab as first line treatment. ... of metastatic colorectal cancer. The committee also asked for...

  • Tocilizumab Final DSU Report

    https://sheffield.ac.uk/media/33944/download?attachment
    evaluated from a cost-effectiveness perspective. Roche have argued that the lifetime costs. ... argued that the mixed treatment comparison (MTC) of ACR response rates demonstrates that. ... by the Committee and tocilizumab was not recommended....

  • REPORT2 OsteoSR DRAFT with NICE comments 22 09 10 KRA AW

    https://sheffield.ac.uk/media/33926/download?attachment
    QUESTIONS TO BE ADDRESSED The questions to be addressed in this report are;. ... between the placebo and treated groups will be biased (Yusuf et al, 1991). ... Secondly, the argument of statistical power/significance for a RR analysis is fallacious.

  • Innovation - final DSU report

    https://sheffield.ac.uk/media/34159/download?attachment
    It examines. how the current approach to appraisal rewards valuable innovations and provides. ... 4. protected by patents. Section 3 describes the general principles of patent protection. ... whether the current methods employed by NICE adequately...
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  • Final DSU report - Alzheimers disease v2 100309

    https://sheffield.ac.uk/media/33895/download?attachment
    1. DONEPEZIL, RIVASTIGMINE, GALANTAMINE AND MEMANTINE FOR THE TREATMENT OF ALZHEIMER’S DISEASE:. ... A REVIEW OF COMMENTS SUBMITTED BY CONSULTEES ON. THE RELIABILITY OF ECONOMIC MODEL. ... disease was published in September 2007. An economic model...

  • Azacitidine FINAL submitted to NICE 28.09.10

    https://sheffield.ac.uk/media/33922/download?attachment
    incorporated into the Celgene economic model. The DSU considers that the utility values. ... effectiveness analysis. In addition, the incorporation of the new utility data does not. ... practice patterns and the characteristics of patients receiving...

  • DSU report v7

    https://sheffield.ac.uk/media/33900/download?attachment
    preliminary recommendations and referred to in section 4.3.9 of the ACD. ... and monitoring cost differs. 2. REPLICATION OF STATED CORRECTIONS TO THE MANUFACTURER MODELS. ... The LRiG assessment report identified that there is no BASFI progression...

  • Comments on Mixed Treatment Comparison with cover

    https://sheffield.ac.uk/media/33915/download?attachment
    Or to justify the non standard approach to modelling they take (discussed below)? ... which generalises to the full MTC model that has been used more recently. ... comments) outlines what further trials are available to include in the MTC network....

  • Sheffield Economic Research Paper Series

    https://sheffield.ac.uk/media/4011/download?attachment
    stationary process. While the seminal overlapping wage contract model of Phelps (1978) and. ... The standard overlapping wage-contracting model assumes wage and price stickiness is the. ... Interestingly, the issue of inflation rate dispersion and...

  • DSU report v7

    https://sheffield.ac.uk/media/33899/download?attachment
    The Wyeth model gave results of £20k for etanercept and £39k for infliximab. ... These ICERs were very different from those reported by the independent assessment group. ... FINAL REPORT. 9. 3. Comparison of the Abbott and LRiG models for...